Danio rerio

0 known processes

cops3

COP9 constitutive photomorphogenic homolog subunit 3

(Aliases: zgc:77615,wu:fk59f01,zgc:55643,wu:fc32a02,zgc:111903)

cops3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.706
cellular macromolecule metabolic processGO:00442603910.580
embryo development ending in birth or egg hatchingGO:00097922710.425
regulation of metabolic processGO:00192223590.356
protein modification processGO:00362111000.296
regulation of macromolecule metabolic processGO:00602553170.271
mitotic g2 dna damage checkpointGO:000709530.247
protein metabolic processGO:00195381830.224
regulation of cellular metabolic processGO:00313233200.210
lateral inhibitionGO:004633110.192
heterocycle metabolic processGO:00464832900.184
locomotionGO:00400113130.184
modification dependent protein catabolic processGO:001994130.172
protein polyubiquitinationGO:000020940.169
regulation of gene expressionGO:00104682650.166
organic cyclic compound metabolic processGO:19013603010.148
gene expressionGO:00104672520.146
cellular nitrogen compound metabolic processGO:00346412900.145
agingGO:000756820.142
single fertilizationGO:000733830.138
regulation of primary metabolic processGO:00800903110.138
nucleic acid metabolic processGO:00903042440.137
nitrogen compound metabolic processGO:00068073190.133
cellular aromatic compound metabolic processGO:00067252950.132
organic substance biosynthetic processGO:19015762890.132
cellular response to nutrient levelsGO:003166920.124
regulation of nitrogen compound metabolic processGO:00511712510.123
positive regulation of biological processGO:00485182530.121
negative regulation of cellular processGO:00485232830.118
modification dependent macromolecule catabolic processGO:004363230.118
positive regulation of cellular processGO:00485222010.111
cellular protein metabolic processGO:00442671290.110
regulation of nucleobase containing compound metabolic processGO:00192192500.109
negative regulation of biological processGO:00485193040.103
signal transductionGO:00071654550.100
neuron developmentGO:00486662620.098
apoptotic processGO:00069151160.096
reproductionGO:0000003400.094
cellular response to external stimulusGO:007149620.094
response to stressGO:00069502630.094
aromatic compound biosynthetic processGO:00194382170.093
pronuclear migrationGO:003504610.092
biosynthetic processGO:00090582940.092
regulation of rna metabolic processGO:00512522240.091
single organism metabolic processGO:00447102170.091
fertilizationGO:000956630.089
protein acetylationGO:000647320.088
positive regulation of nitrogen compound metabolic processGO:0051173690.088
cellular component assemblyGO:00226071700.085
nucleobase containing compound metabolic processGO:00061392740.083
cytokinesisGO:000091030.083
regulation of transcription dna templatedGO:00063552130.081
single organism organelle organizationGO:19025891990.081
response to external stimulusGO:00096052640.081
regulation of cell cycleGO:0051726520.080
cellular response to extracellular stimulusGO:003166820.079
regulation of cellular macromolecule biosynthetic processGO:20001122220.077
cellular protein catabolic processGO:004425740.076
mitotic dna integrity checkpointGO:004477440.075
cellular component biogenesisGO:00440851780.075
ubiquitin dependent protein catabolic processGO:000651130.074
protein modification by small protein conjugation or removalGO:0070647140.072
rna metabolic processGO:00160702190.071
regulation of biological qualityGO:00650082630.071
autophagyGO:000691440.069
cellular component morphogenesisGO:00329893360.069
macromolecule biosynthetic processGO:00090592270.068
cell surface receptor signaling pathwayGO:00071663250.067
mitotic g2 m transition checkpointGO:004481830.067
nucleic acid templated transcriptionGO:00976591810.066
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.066
regionalizationGO:00030022740.066
mitotic dna damage checkpointGO:004477340.065
multi organism processGO:00517041340.065
regulation of signal transductionGO:00099662250.063
positive regulation of cellular metabolic processGO:0031325940.061
macromolecule modificationGO:00434121110.061
rna biosynthetic processGO:00327741810.060
heterocycle biosynthetic processGO:00181302150.059
sensory organ developmentGO:00074233930.058
protein acylationGO:004354330.057
nuclear migrationGO:000709730.057
nucleobase containing compound biosynthetic processGO:00346542050.057
regulation of rna biosynthetic processGO:20011412130.056
regulation of signalingGO:00230512350.054
stem cell divisionGO:001714510.054
response to nutrientGO:000758430.053
cell morphogenesis involved in neuron differentiationGO:00486671630.052
proteolysis involved in cellular protein catabolic processGO:005160330.052
organelle organizationGO:00069962270.052
eye developmentGO:00016542770.052
neuron differentiationGO:00301823530.051
peptidyl lysine acetylationGO:001839420.051
cellular protein modification processGO:00064641000.051
regulation of developmental processGO:00507932470.050
neuron projection morphogenesisGO:00488121610.050
regulation of multicellular organism growthGO:004001440.049
cell proliferationGO:0008283800.049
regulation of cell communicationGO:00106462320.049
proteasomal protein catabolic processGO:001049820.049
cellular macromolecule biosynthetic processGO:00346452240.049
cell deathGO:00082191210.048
protein stabilizationGO:005082120.047
establishment of localizationGO:00512342440.047
meiotic nuclear divisionGO:000712640.047
response to chemicalGO:00422213200.046
cellular component disassemblyGO:002241110.045
regulation of meiotic cell cycleGO:005144510.045
positive regulation of cellular catabolic processGO:003133130.045
cell morphogenesis involved in differentiationGO:00009041950.045
cellular nitrogen compound biosynthetic processGO:00442712180.044
mitotic cell cycleGO:0000278640.044
regulation of response to stimulusGO:00485832690.044
macromolecular complex disassemblyGO:003298410.044
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.044
pole plasm assemblyGO:000731540.044
generation of neuronsGO:00486993850.044
single organism reproductive processGO:0044702400.043
transcription from rna polymerase ii promoterGO:0006366800.042
taxisGO:00423301090.042
double strand break repairGO:000630230.042
programmed cell deathGO:00125011190.042
multicellular organism growthGO:003526440.041
phosphate containing compound metabolic processGO:00067961080.040
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.040
cellular amine metabolic processGO:004410620.040
small molecule metabolic processGO:0044281770.040
positive regulation of metabolic processGO:00098931080.039
muscle structure developmentGO:00610611960.039
multi organism cellular processGO:004476420.039
double strand break repair via homologous recombinationGO:000072410.038
gtp metabolic processGO:004603940.038
regulation of multicellular organismal processGO:00512392770.038
cell fate commitmentGO:0045165990.038
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.037
g2 dna damage checkpointGO:003157230.037
developmental process involved in reproductionGO:0003006270.037
positive regulation of catabolic processGO:000989640.036
regulation of nucleotide catabolic processGO:003081120.036
cell morphogenesisGO:00009022890.036
dna templated transcription elongationGO:000635430.036
negative regulation of metabolic processGO:0009892860.035
mitochondrion organizationGO:000700540.035
female sex differentiationGO:004666040.035
positive regulation of transcription dna templatedGO:0045893570.034
cell projection organizationGO:00300302840.034
internal protein amino acid acetylationGO:000647520.034
neuron projection developmentGO:00311751800.034
gtp catabolic processGO:000618420.034
reproductive processGO:0022414400.034
catabolic processGO:0009056320.034
phagocytosisGO:000690930.033
deathGO:00162651210.033
chordate embryonic developmentGO:00430092710.033
regulation of macromolecule biosynthetic processGO:00105562250.033
protein modification by small protein conjugationGO:0032446130.033
transportGO:00068102200.032
cell migrationGO:00164772370.032
cell projection morphogenesisGO:00488582440.032
positive regulation of macromolecule metabolic processGO:0010604930.032
positive regulation of transportGO:005105020.032
cellular process involved in reproduction in multicellular organismGO:0022412280.032
intracellular mrna localizationGO:000829810.032
organonitrogen compound metabolic processGO:1901564740.032
internal peptidyl lysine acetylationGO:001839320.032
regulation of protein modification by small protein conjugation or removalGO:190332030.032
maintenance of locationGO:005123540.032
regulation of cellular biosynthetic processGO:00313262450.031
regulation of nucleic acid templated transcriptionGO:19035062130.031
cellular response to stressGO:0033554620.031
positive regulation of nucleobase containing compound metabolic processGO:0045935690.031
regulation of cellular amine metabolic processGO:003323800.031
localization of cellGO:00516742440.031
phosphorus metabolic processGO:00067931090.030
organic cyclic compound biosynthetic processGO:19013622230.030
dna metabolic processGO:0006259270.030
positive regulation of cellular biosynthetic processGO:0031328680.030
regulation of cellular amino acid metabolic processGO:000652100.029
locomotor rhythmGO:004547530.029
protein polymerizationGO:005125840.029
mitotic cell cycle processGO:1903047480.029
oxoacid metabolic processGO:0043436310.029
organic acid metabolic processGO:0006082310.029
transcription dna templatedGO:00063511810.029
regulation of transcription from rna polymerase ii promoterGO:00063571140.029
negative regulation of cell communicationGO:0010648960.028
protein modification by small protein removalGO:007064610.028
symbiosis encompassing mutualism through parasitismGO:004440340.028
macromolecular complex subunit organizationGO:0043933740.028
amine metabolic processGO:000930820.028
guanosine containing compound metabolic processGO:190106840.028
regulation of nucleoside metabolic processGO:000911820.028
rna localizationGO:000640340.027
negative regulation of mitotic cell cycleGO:0045930110.027
regulation of proteolysisGO:0030162240.027
development of primary female sexual characteristicsGO:004654540.027
regulation of gtp catabolic processGO:003312420.027
muscle organ developmentGO:00075171010.027
cellular biosynthetic processGO:00442492860.027
cellular response to dna damage stimulusGO:0006974240.027
regulation of mitotic cell cycleGO:0007346250.027
gamete generationGO:0007276330.026
positive regulation of purine nucleotide catabolic processGO:003312310.026
production of molecular mediator of immune responseGO:000244020.026
dna templated transcription initiationGO:000635210.026
meiotic chromosome segregationGO:004513230.026
stem cell proliferationGO:007208940.026
neuron projection guidanceGO:0097485860.026
dendrite guidanceGO:007098300.026
lipid storageGO:001991510.026
multicellular organismal reproductive processGO:0048609350.026
cell cycleGO:0007049930.026
cell motilityGO:00488702440.026
chemotaxisGO:00069351040.025
viral processGO:001603210.025
cellular amino acid metabolic processGO:000652070.025
chromosome organizationGO:0051276310.025
regulation of protein ubiquitinationGO:003139630.025
regulation of dna templated transcription elongationGO:003278430.024
positive regulation of cellular component biogenesisGO:004408930.024
regulation of purine nucleotide catabolic processGO:003312120.024
cellular component movementGO:00069283350.024
cellular response to chemical stimulusGO:00708871570.024
organic substance catabolic processGO:1901575280.024
dorsal ventral pattern formationGO:00099531250.024
positive regulation of macromolecule biosynthetic processGO:0010557590.024
establishment of organelle localizationGO:0051656450.024
positive regulation of cell cycleGO:004578730.024
cytoskeleton organizationGO:0007010960.023
regulation of establishment of protein localizationGO:007020140.023
regulation of molecular functionGO:0065009700.023
female gonad developmentGO:000858540.023
regulation of biosynthetic processGO:00098892500.023
positive regulation of rna biosynthetic processGO:1902680570.023
central nervous system developmentGO:00074173870.023
regulation of cellular ketone metabolic processGO:001056570.023
negative regulation of macromolecule metabolic processGO:0010605760.023
cellular response to starvationGO:000926710.023
interspecies interaction between organismsGO:004441940.023
organelle localizationGO:0051640490.023
positive regulation of nucleoside metabolic processGO:004597910.023
positive regulation of cellular amino acid metabolic processGO:004576400.023
regulation of stem cell proliferationGO:007209120.022
regulation of protein complex assemblyGO:004325430.022
neuroblast proliferationGO:000740520.022
meiosis iGO:000712710.022
positive regulation of molecular functionGO:0044093330.022
ovulation cycleGO:004269820.022
chromatin modificationGO:0016568210.022
recombinational repairGO:000072510.022
positive regulation of nucleotide catabolic processGO:003081310.022
protein localization to plasma membraneGO:007265910.022
nuclear transportGO:005116940.021
regulation of chromosome segregationGO:005198310.021
cellular ketone metabolic processGO:0042180110.021
positive regulation of chromosome organizationGO:200125210.021
cellular localizationGO:0051641970.021
carboxylic acid metabolic processGO:0019752220.021
negative regulation of ras protein signal transductionGO:004658010.021
cell part morphogenesisGO:00329902460.021
oocyte anterior posterior axis specificationGO:000731440.021
growthGO:00400071740.021
regulation of cell activationGO:005086510.021
regulation of cellular protein metabolic processGO:0032268520.020
nuclear importGO:005117030.020
developmental growthGO:00485891660.020
regulation of protein metabolic processGO:0051246560.020
anterior posterior pattern specificationGO:00099521520.020
glial cell differentiationGO:0010001420.020
regulation of protein transportGO:005122330.020
cellular catabolic processGO:0044248270.020
positive regulation of cellular amine metabolic processGO:003324000.020
single organism localizationGO:19025782250.020
regulation of alternative mrna splicing via spliceosomeGO:000038110.020
cell divisionGO:0051301200.020
cell cell signalingGO:0007267520.019
regulation of cell cycle processGO:0010564200.019
regulation of protein catabolic processGO:004217610.019
response to abiotic stimulusGO:00096281220.019
synaptic growth at neuromuscular junctionGO:005112420.019
axon developmentGO:00615641660.019
intracellular signal transductionGO:0035556850.019
negative regulation of protein phosphorylationGO:000193340.019
protein import into nucleusGO:000660630.019
negative regulation of cell cycle processGO:001094890.019
embryonic organ morphogenesisGO:00485622740.019
regulation of cellular component organizationGO:0051128860.018
behaviorGO:0007610740.018
embryonic organ developmentGO:00485683810.018
positive regulation of gtp catabolic processGO:003312610.018
regulation of neural precursor cell proliferationGO:200017730.018
negative regulation of gene expressionGO:0010629650.018
protein dephosphorylationGO:000647030.018
response to topologically incorrect proteinGO:003596620.018
gastrulationGO:00073692080.018
centrosome organizationGO:005129710.018
regulation of cell shapeGO:000836010.018
regulation of cell deathGO:00109411030.018
compound eye developmentGO:004874920.018
regulation of mitotic cell cycle phase transitionGO:190199080.018
regulation of gtpase activityGO:004308720.017
positive regulation of protein complex assemblyGO:003133420.017
positive regulation of nucleic acid templated transcriptionGO:1903508570.017
positive regulation of gene expressionGO:0010628710.017
immune system processGO:00023762410.017
establishment of protein localization to organelleGO:007259440.017
meiotic cell cycle processGO:190304630.017
regulation of cell cycle phase transitionGO:190198780.017
purine ribonucleoside monophosphate catabolic processGO:000916940.017
ribosomal small subunit biogenesisGO:004227420.017
regulation of synapse organizationGO:005080730.017
protein heterooligomerizationGO:005129110.017
response to drugGO:004249330.017
gliogenesisGO:0042063450.017
protein localization to nucleusGO:003450430.017
regulation of apoptotic processGO:0042981980.016
regulation of gene expression epigeneticGO:0040029110.016
regulation of glial cell differentiationGO:004568540.016
negative regulation of response to stimulusGO:00485851040.016
ribonucleoside monophosphate catabolic processGO:000915840.016
endocrine processGO:005088620.016
protein complex assemblyGO:0006461300.016
sexual reproductionGO:0019953360.016
protein complex disassemblyGO:004324110.016
regulation of peptidyl tyrosine phosphorylationGO:005073010.016
protein complex subunit organizationGO:0071822460.016
skin developmentGO:0043588540.016
centrosome cycleGO:000709810.016
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.016
camera type eye developmentGO:00430102220.015
mitotic cell cycle phase transitionGO:004477290.015
macroautophagyGO:001623610.015
cell cycle g2 m phase transitionGO:004483940.015
negative regulation of cell cycle phase transitionGO:190198850.015
phosphorylationGO:0016310690.015
regulation of synaptic growth at neuromuscular junctionGO:000858210.015
carbohydrate derivative metabolic processGO:1901135610.015
stem cell maintenanceGO:001982740.014
positive regulation of histone modificationGO:003105810.014
ovulation cycle processGO:002260220.014
regulation of anatomical structure morphogenesisGO:00226031300.014
developmental programmed cell deathGO:001062340.014
microtubule polymerization or depolymerizationGO:003110930.014
transcription elongation from rna polymerase ii promoterGO:000636830.014
protein targeting to nucleusGO:004474430.014
protein complex biogenesisGO:0070271300.014
regulation of nuclear divisionGO:005178390.014
nucleocytoplasmic transportGO:000691340.014
microtubule cytoskeleton organization involved in mitosisGO:190285010.014
circadian sleep wake cycle processGO:002241020.014
positive regulation of secretion by cellGO:190353210.014
cell cycle processGO:0022402530.014
negative regulation of nitrogen compound metabolic processGO:0051172590.014
atp catabolic processGO:000620040.014
neuron neuron synaptic transmissionGO:000727010.014
regulation of bindingGO:005109830.014
positive regulation of gtpase activityGO:004354710.014
positive regulation of biosynthetic processGO:0009891680.014
cytoskeleton dependent cytokinesisGO:006164030.013
positive regulation of response to stimulusGO:0048584800.013
regulation of multicellular organismal developmentGO:20000262230.013
negative regulation of synapse assemblyGO:005196420.013
g2 m transition of mitotic cell cycleGO:000008640.013
regulation of extrinsic apoptotic signaling pathwayGO:200123630.013
cell cycle g1 s phase transitionGO:004484310.013
negative regulation of stem cell differentiationGO:200073720.013
single organism nuclear importGO:190259330.013
proteolysisGO:0006508380.013
oocyte constructionGO:000730850.013
positive regulation of signal transductionGO:0009967560.013
positive regulation of dna metabolic processGO:005105410.013
regulation of protein localization to nucleusGO:190018020.013
positive regulation of apoptotic signaling pathwayGO:200123510.013
response to glucoseGO:000974930.013
positive regulation of cell activationGO:005086710.013
protein importGO:001703830.013
multi organism reproductive processGO:0044703360.013
carbohydrate homeostasisGO:003350010.013
meiotic spindle organizationGO:000021210.013
response to hexoseGO:000974630.013
renal system developmentGO:0072001940.013
odontogenesis of dentin containing toothGO:004247510.013
response to monosaccharideGO:003428430.013
regulation of cellular protein catabolic processGO:190336210.013
positive regulation of stem cell proliferationGO:200064810.013
negative regulation of programmed cell deathGO:0043069580.013
axonogenesisGO:00074091520.013
nucleoside monophosphate catabolic processGO:000912540.013
organelle fissionGO:0048285230.012
regulation of synapse assemblyGO:005196330.012
translational initiationGO:000641330.012
ncrna catabolic processGO:003466110.012
ovarian follicle developmentGO:000154120.012
g1 s transition of mitotic cell cycleGO:000008210.012
spindle assemblyGO:005122520.012
negative regulation of cell cycleGO:0045786140.012
regulation of cell proliferationGO:0042127370.012
positive regulation of rna metabolic processGO:0051254590.012
tube morphogenesisGO:00352393490.012
maternal determination of anterior posterior axis embryoGO:000835840.012
wnt signaling pathwayGO:0016055800.012
sex determinationGO:000753010.012
macromolecular complex assemblyGO:0065003350.012
posttranscriptional regulation of gene expressionGO:0010608140.012
negative regulation of developmental processGO:0051093650.012
adult behaviorGO:003053420.012
morphogenesis of an epitheliumGO:00020093330.012
neuromuscular synaptic transmissionGO:000727420.011
cell agingGO:000756920.011
smoothened signaling pathwayGO:0007224300.011
protein depolymerizationGO:005126110.011
cell cell recognitionGO:000998810.011
positive regulation of signalingGO:0023056560.011
negative regulation of cellular metabolic processGO:0031324770.011
extrinsic apoptotic signaling pathwayGO:009719130.011
epidermis developmentGO:0008544480.011
glucose homeostasisGO:004259310.011
erk1 and erk2 cascadeGO:007037140.011
cellular carbohydrate metabolic processGO:004426240.011
dna biosynthetic processGO:007189730.011
regulation of sequence specific dna binding transcription factor activityGO:005109090.011
positive regulation of chromatin modificationGO:190331010.011
negative regulation of small gtpase mediated signal transductionGO:005105810.011
microtubule organizing center organizationGO:003102310.011
axis specificationGO:0009798430.011
positive regulation of multi organism processGO:004390230.011
blood vessel developmentGO:00015682460.011
response to woundingGO:00096111160.011
b cell mediated immunityGO:001972430.011
response to biotic stimulusGO:0009607970.011
regulation of erk1 and erk2 cascadeGO:007037240.011
microtubule polymerizationGO:004678520.011
response to corticosteroidGO:003196010.011
response to other organismGO:0051707970.011
oligodendrocyte differentiationGO:0048709230.011
regulation of phosphorus metabolic processGO:0051174430.011
establishment of synaptic vesicle localizationGO:009748010.011
negative regulation of defense responseGO:003134820.011
regulation of protein import into nucleusGO:004230620.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.011
somitogenesisGO:0001756870.011
establishment of localization in cellGO:0051649770.011
positive regulation of canonical wnt signaling pathwayGO:009026340.011
purine nucleoside monophosphate catabolic processGO:000912840.011
glycerolipid biosynthetic processGO:004501710.011
response to extracellular stimulusGO:0009991100.010
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.010
hatchingGO:003518840.010
negative regulation of catabolic processGO:000989530.010
cell substrate junction assemblyGO:000704420.010
response to endogenous stimulusGO:0009719830.010
positive regulation of notch signaling pathwayGO:004574730.010
regulation of rho protein signal transductionGO:003502320.010
dna integrity checkpointGO:003157060.010
circadian sleep wake cycleGO:004274520.010
regulation of catalytic activityGO:0050790550.010
heart developmentGO:00075073130.010
positive regulation of cell communicationGO:0010647560.010
leukocyte proliferationGO:007066110.010
negative regulation of signal transductionGO:0009968940.010
positive regulation of small gtpase mediated signal transductionGO:005105710.010
response to hydrogen peroxideGO:004254230.010
urogenital system developmentGO:0001655970.010
negative regulation of apoptotic processGO:0043066550.010
protein secretionGO:000930610.010
membrane fusionGO:006102520.010

cops3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.031
cancerDOID:16200.031
disease of cellular proliferationDOID:1456600.031
disease of anatomical entityDOID:700.030
musculoskeletal system diseaseDOID:1700.018
nervous system diseaseDOID:86300.015
muscular diseaseDOID:008000000.014
muscle tissue diseaseDOID:6600.013
myopathyDOID:42300.012