Danio rerio

24 known processes

cops6

COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)

(Aliases: zgc:112075)

cops6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of primary metabolic processGO:00800903110.110
gene expressionGO:00104672520.101
cellular macromolecule metabolic processGO:00442603910.091
regulation of cellular biosynthetic processGO:00313262450.086
signal transductionGO:00071654550.079
small molecule metabolic processGO:0044281770.077
heart developmentGO:00075073130.077
heterocycle metabolic processGO:00464832900.076
larval developmentGO:000216420.076
phagocytosisGO:000690930.075
organic cyclic compound metabolic processGO:19013603010.075
nitrogen compound metabolic processGO:00068073190.074
generation of neuronsGO:00486993850.071
cellular nitrogen compound metabolic processGO:00346412900.071
biosynthetic processGO:00090582940.070
regulation of nitrogen compound metabolic processGO:00511712510.070
regulation of establishment of protein localizationGO:007020140.068
cell morphogenesisGO:00009022890.067
regulation of cellular metabolic processGO:00313233200.065
regulation of metabolic processGO:00192223590.064
multicellular organism growthGO:003526440.063
regulation of protein transportGO:005122330.061
cellular component morphogenesisGO:00329893360.060
nucleobase containing compound metabolic processGO:00061392740.058
cell migration involved in gastrulationGO:0042074790.057
regulation of biosynthetic processGO:00098892500.057
agingGO:000756820.056
cellular macromolecule biosynthetic processGO:00346452240.056
locomotionGO:00400113130.054
maintenance of locationGO:005123540.054
guanosine containing compound metabolic processGO:190106840.053
establishment of protein localization to organelleGO:007259440.052
stem cell divisionGO:001714510.052
single organism metabolic processGO:00447102170.052
positive regulation of cellular component biogenesisGO:004408930.051
cell surface receptor signaling pathwayGO:00071663250.051
negative regulation of protein phosphorylationGO:000193340.050
regulation of nucleobase containing compound metabolic processGO:00192192500.049
single organism organelle organizationGO:19025891990.049
nucleic acid metabolic processGO:00903042440.049
macromolecule biosynthetic processGO:00090592270.048
cognitionGO:005089010.048
regulation of signalingGO:00230512350.048
cellular aromatic compound metabolic processGO:00067252950.048
protein import into nucleusGO:000660630.048
cell projection organizationGO:00300302840.048
regulation of cell shapeGO:000836010.047
nucleobase containing compound biosynthetic processGO:00346542050.047
guanosine containing compound catabolic processGO:190106920.047
positive regulation of transportGO:005105020.047
single organism nuclear importGO:190259330.046
positive regulation of catabolic processGO:000989640.046
regulation of protein localization to nucleusGO:190018020.046
response to chemicalGO:00422213200.046
amine metabolic processGO:000930820.045
protein localization to nucleusGO:003450430.045
neuron differentiationGO:00301823530.045
organic substance biosynthetic processGO:19015762890.044
somatic muscle developmentGO:000752540.044
organic acid metabolic processGO:0006082310.044
organonitrogen compound metabolic processGO:1901564740.043
cellular amine metabolic processGO:004410620.043
protein importGO:001703830.043
protein targeting to nucleusGO:004474430.043
aromatic compound biosynthetic processGO:00194382170.042
stem cell maintenanceGO:001982740.042
cellular ketone metabolic processGO:0042180110.042
regulation of intracellular protein transportGO:003315730.041
autophagyGO:000691440.041
heterocycle biosynthetic processGO:00181302150.041
cellular protein metabolic processGO:00442671290.041
organelle organizationGO:00069962270.041
gtp metabolic processGO:004603940.041
establishment of localizationGO:00512342440.040
meiotic nuclear divisionGO:000712640.040
nuclear transportGO:005116940.040
negative regulation of biological processGO:00485193040.040
negative regulation of protein transportGO:005122430.040
single organism localizationGO:19025782250.039
cellular biosynthetic processGO:00442492860.039
positive regulation of cellular catabolic processGO:003133130.039
digestive system developmentGO:00551232890.039
single organism transportGO:00447652060.039
cytokinesisGO:000091030.038
nucleocytoplasmic transportGO:000691340.038
regulation of nucleotide catabolic processGO:003081120.038
macromolecule modificationGO:00434121110.038
blood vessel developmentGO:00015682460.038
gtp catabolic processGO:000618420.038
protein metabolic processGO:00195381830.037
regulation of rna metabolic processGO:00512522240.037
regulation of signal transductionGO:00099662250.037
stem cell proliferationGO:007208940.037
mitochondrion organizationGO:000700540.037
response to external stimulusGO:00096052640.037
oxoacid metabolic processGO:0043436310.037
organic cyclic compound biosynthetic processGO:19013622230.037
regulation of developmental processGO:00507932470.036
cellular protein modification processGO:00064641000.036
immune system processGO:00023762410.036
regulation of cellular amine metabolic processGO:003323800.036
regulation of macromolecule metabolic processGO:00602553170.036
nucleic acid templated transcriptionGO:00976591810.035
negative regulation of cellular processGO:00485232830.035
regulation of protein targetingGO:190353320.035
regulation of multicellular organism growthGO:004001440.035
cellular nitrogen compound biosynthetic processGO:00442712180.034
lipid storageGO:001991510.034
regulation of protein import into nucleusGO:004230620.034
determination of left right symmetryGO:00073681790.034
regulation of transcription dna templatedGO:00063552130.034
regulation of synapse organizationGO:005080730.034
regulation of synaptic growth at neuromuscular junctionGO:000858210.034
regulation of cellular ketone metabolic processGO:001056570.033
regulation of rna biosynthetic processGO:20011412130.033
carboxylic acid metabolic processGO:0019752220.033
erk1 and erk2 cascadeGO:007037140.033
positive regulation of biological processGO:00485182530.032
regulation of gtp catabolic processGO:003312420.032
positive regulation of cell cycleGO:004578730.032
tube morphogenesisGO:00352393490.032
transcription dna templatedGO:00063511810.032
skeletal system developmentGO:00015011810.032
localization of cellGO:00516742440.032
regulation of nucleoside metabolic processGO:000911820.032
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.032
gastrulationGO:00073692080.032
cell part morphogenesisGO:00329902460.032
cellular component movementGO:00069283350.031
cell projection morphogenesisGO:00488582440.031
rna metabolic processGO:00160702190.031
positive regulation of epithelial cell proliferationGO:005067910.031
cellular localizationGO:0051641970.031
neuron projection developmentGO:00311751800.031
phosphorus metabolic processGO:00067931090.031
proteasomal protein catabolic processGO:001049820.031
phosphate containing compound metabolic processGO:00067961080.030
cellular response to external stimulusGO:007149620.030
digestive tract developmentGO:00485652650.030
hemopoiesisGO:00300971830.030
digestive tract morphogenesisGO:00485462310.030
positive regulation of neuron apoptotic processGO:004352510.030
regulation of biological qualityGO:00650082630.030
vasculature developmentGO:00019442780.029
specification of symmetryGO:00097992040.029
neuron developmentGO:00486662620.029
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.029
regulation of nucleic acid templated transcriptionGO:19035062130.029
transportGO:00068102200.028
regulation of protein catabolic processGO:004217610.028
negative regulation of protein serine threonine kinase activityGO:007190120.028
regulation of cellular amino acid metabolic processGO:000652100.028
neuroblast proliferationGO:000740520.028
cell morphogenesis involved in neuron differentiationGO:00486671630.028
cellular response to nutrient levelsGO:003166920.028
cell motilityGO:00488702440.028
protein modification processGO:00362111000.028
cell substrate adhesionGO:003158940.028
regulation of cell communicationGO:00106462320.028
negative regulation of kinase activityGO:003367340.028
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.028
regulation of cellular macromolecule biosynthetic processGO:20001122220.027
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.027
regulation of multicellular organismal processGO:00512392770.027
hematopoietic or lymphoid organ developmentGO:00485341910.027
wnt signaling pathwayGO:0016055800.027
response to nutrientGO:000758430.027
renal system developmentGO:0072001940.027
regulation of purine nucleotide catabolic processGO:003312120.027
cell migrationGO:00164772370.026
determination of bilateral symmetryGO:00098552040.026
negative regulation of protein kinase activityGO:000646940.026
regulation of meiotic cell cycleGO:005144510.026
nuclear importGO:005117030.026
cellular response to extracellular stimulusGO:003166820.026
cellular component biogenesisGO:00440851780.026
exocytosisGO:000688710.026
extrinsic apoptotic signaling pathwayGO:009719130.026
macroautophagyGO:001623610.026
regulation of peptidyl tyrosine phosphorylationGO:005073010.026
chordate embryonic developmentGO:00430092710.026
positive regulation of cellular processGO:00485222010.026
organelle fusionGO:004828430.025
secondary metabolic processGO:001974830.025
regulation of autophagyGO:001050630.025
regulation of nucleocytoplasmic transportGO:004682220.025
embryonic heart tube developmentGO:00350501330.025
negative regulation of protein localization to nucleusGO:190018120.025
urogenital system developmentGO:0001655970.025
actin polymerization or depolymerizationGO:000815420.025
protein secretionGO:000930610.025
regulation of cytokine productionGO:000181730.025
positive regulation of map kinase activityGO:004340630.025
system processGO:00030081850.024
regulation of response to stimulusGO:00485832690.024
neuron projection morphogenesisGO:00488121610.024
negative regulation of nucleocytoplasmic transportGO:004682320.024
rna biosynthetic processGO:00327741810.024
g1 s transition of mitotic cell cycleGO:000008210.024
negative regulation of mapk cascadeGO:004340940.024
positive regulation of stress activated mapk cascadeGO:003287430.023
regionalizationGO:00030022740.023
regulation of cytoplasmic transportGO:190364940.023
osteoclast differentiationGO:003031610.023
regulation of gene expressionGO:00104682650.023
immune system developmentGO:00025201910.023
positive regulation of nitrogen compound metabolic processGO:0051173690.023
actin cytoskeleton organizationGO:0030036630.023
embryonic organ morphogenesisGO:00485622740.022
regulation of bindingGO:005109830.022
negative regulation of intracellular transportGO:003238730.022
cellular amino acid metabolic processGO:000652070.022
morphogenesis of an epitheliumGO:00020093330.022
post embryonic organ developmentGO:004856940.022
response to stressGO:00069502630.022
regulation of protein complex assemblyGO:004325430.022
synaptic growth at neuromuscular junctionGO:005112420.022
regulation of exocytosisGO:001715710.022
liver developmentGO:0001889960.022
phosphorylationGO:0016310690.022
positive regulation of dna metabolic processGO:005105410.022
membrane fusionGO:006102520.022
regulation of synapse assemblyGO:005196330.021
response to other organismGO:0051707970.021
negative regulation of cytoplasmic transportGO:190365020.021
regulation of multicellular organismal developmentGO:20000262230.021
cellular response to starvationGO:000926710.021
heart morphogenesisGO:00030071560.021
regulation of fibroblast growth factor receptor signaling pathwayGO:0040036200.021
phagocytosis engulfmentGO:000691110.021
small gtpase mediated signal transductionGO:000726480.021
cellular response to biotic stimulusGO:007121630.021
cellular carbohydrate metabolic processGO:004426240.021
cell cycle g1 s phase transitionGO:004484310.021
b cell differentiationGO:003018310.021
regulation of epithelial cell proliferationGO:005067830.021
somatic stem cell maintenanceGO:003501910.021
cell matrix adhesionGO:000716040.021
negative regulation of secretionGO:005104820.021
cilium organizationGO:0044782710.021
negative regulation of gene expressionGO:0010629650.020
embryo development ending in birth or egg hatchingGO:00097922710.020
symbiosis encompassing mutualism through parasitismGO:004440340.020
carbohydrate derivative metabolic processGO:1901135610.020
mitotic cell cycleGO:0000278640.020
chemosensory behaviorGO:000763510.020
kidney developmentGO:0001822920.020
axonogenesisGO:00074091520.020
angiogenesisGO:00015251580.020
regulation of gtpase activityGO:004308720.020
positive regulation of canonical wnt signaling pathwayGO:009026340.020
spermatid differentiationGO:004851520.020
lateral inhibitionGO:004633110.020
cellular component assemblyGO:00226071700.020
establishment of localization in cellGO:0051649770.020
convergent extensionGO:00600261180.020
membrane invaginationGO:001032410.020
negative regulation of cell communicationGO:0010648960.019
embryonic organ developmentGO:00485683810.019
myeloid cell differentiationGO:0030099860.019
ameboidal type cell migrationGO:00016671430.019
centrosome organizationGO:005129710.019
somite developmentGO:0061053960.019
proteolysis involved in cellular protein catabolic processGO:005160330.019
modification dependent macromolecule catabolic processGO:004363230.019
meiotic cell cycle processGO:190304630.019
spermatid developmentGO:000728620.019
i kappab kinase nf kappab signalingGO:000724940.019
cellular response to chemical stimulusGO:00708871570.019
cellular component disassemblyGO:002241110.019
regulation of cell activationGO:005086510.019
germ line stem cell maintenanceGO:003071820.019
developmental growthGO:00485891660.019
negative regulation of intracellular protein transportGO:009031730.019
positive regulation of cellular amino acid metabolic processGO:004576400.019
central nervous system developmentGO:00074173870.019
regulation of dna replicationGO:000627530.018
actin filament polymerizationGO:003004120.018
rna localizationGO:000640340.018
negative regulation of protein import into nucleusGO:004230820.018
regulation of reproductive processGO:200024140.018
tissue remodelingGO:004877140.018
response to external biotic stimulusGO:0043207970.018
positive regulation of purine nucleotide catabolic processGO:003312310.018
negative regulation of map kinase activityGO:004340720.018
positive regulation of cellular amine metabolic processGO:003324000.018
negative regulation of signalingGO:0023057960.018
regulation of macromolecule biosynthetic processGO:00105562250.018
regulation of cell substrate adhesionGO:001081010.018
glycoprotein metabolic processGO:0009100230.018
regulation of stem cell differentiationGO:200073640.017
positive regulation of nucleoside metabolic processGO:004597910.017
regulation of molecular functionGO:0065009700.017
single organism cellular localizationGO:1902580460.017
cell morphogenesis involved in differentiationGO:00009041950.017
protein phosphorylationGO:0006468470.017
sequestering of metal ionGO:005123830.017
cellular response to xenobiotic stimulusGO:0071466350.017
b cell activationGO:004211320.017
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.017
convergent extension involved in gastrulationGO:0060027710.017
muscle structure developmentGO:00610611960.017
blood vessel morphogenesisGO:00485142160.017
regulation of mrna processingGO:005068430.017
modification dependent protein catabolic processGO:001994130.017
positive regulation of gtp catabolic processGO:003312610.017
ubiquitin dependent protein catabolic processGO:000651130.017
response to biotic stimulusGO:0009607970.017
negative regulation of defense responseGO:003134820.017
positive regulation of cell divisionGO:005178120.017
meiotic chromosome segregationGO:004513230.017
positive regulation of neuron deathGO:190121610.017
extracellular structure organizationGO:0043062270.017
macromolecule localizationGO:0033036540.016
microtubule based processGO:0007017600.016
response to organic substanceGO:00100331530.016
sensory organ developmentGO:00074233930.016
canonical wnt signaling pathwayGO:0060070480.016
cellular protein catabolic processGO:004425740.016
epithelial cell differentiationGO:00308551160.016
establishment of protein localization to plasma membraneGO:009000210.016
single organism membrane fusionGO:004480120.016
reflexGO:006000420.016
axon developmentGO:00615641660.016
chemotaxisGO:00069351040.016
regulation of cellular component organizationGO:0051128860.016
positive regulation of nucleotide catabolic processGO:003081310.016
eye developmentGO:00016542770.016
cytoskeleton dependent cytokinesisGO:006164030.016
regulation of cell matrix adhesionGO:000195210.016
response to carbohydrateGO:000974330.015
cilium morphogenesisGO:0060271850.015
heart loopingGO:0001947940.015
regulation of cellular protein catabolic processGO:190336210.015
spindle assemblyGO:005122520.015
peptide transportGO:001583310.015
carbohydrate homeostasisGO:003350010.015
regulation of anatomical structure morphogenesisGO:00226031300.015
protein localization to plasma membraneGO:007265910.015
centrosome cycleGO:000709810.015
protein complex localizationGO:003150310.015
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.015
female meiotic divisionGO:000714320.015
regulation of erk1 and erk2 cascadeGO:007037240.015
negative regulation of epithelial cell proliferationGO:005068010.015
enzyme linked receptor protein signaling pathwayGO:00071671060.015
growthGO:00400071740.015
negative regulation of response to stimulusGO:00485851040.015
negative regulation of secretion by cellGO:190353120.015
negative regulation of metabolic processGO:0009892860.015
positive regulation of cytokine productionGO:000181920.015
protein polymerizationGO:005125840.015
negative regulation of macromolecule metabolic processGO:0010605760.015
positive regulation of metabolic processGO:00098931080.015
organelle assemblyGO:00709251100.015
intracellular signal transductionGO:0035556850.015
dorsal ventral pattern formationGO:00099531250.015
gland developmentGO:00487321430.015
positive regulation of gtpase activityGO:004354710.015
cytoskeleton organizationGO:0007010960.015
endosomal transportGO:001619720.015
programmed cell deathGO:00125011190.014
negative regulation of nitrogen compound metabolic processGO:0051172590.014
golgi vesicle transportGO:004819330.014
interspecies interaction between organismsGO:004441940.014
positive regulation of nucleobase containing compound metabolic processGO:0045935690.014
locomotor rhythmGO:004547530.014
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.014
chromosome organization involved in meiosisGO:007019210.014
positive regulation of jak stat cascadeGO:004642720.014
meiosis iGO:000712710.014
viral processGO:001603210.014
apoptotic processGO:00069151160.014
multi organism processGO:00517041340.014
primary neural tube formationGO:001402010.014
carbohydrate biosynthetic processGO:001605110.014
negative regulation of signal transductionGO:0009968940.014
positive regulation of cell adhesionGO:004578510.014
segment polarity determinationGO:000736710.014
sequestering of calcium ionGO:005120830.014
regulation of neuron differentiationGO:0045664560.014
regulation of extrinsic apoptotic signaling pathwayGO:200123630.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
smoothened signaling pathwayGO:0007224300.014
regulation of cell differentiationGO:00455951420.013
muscle cell differentiationGO:00426921390.013
cell proliferationGO:0008283800.013
regulation of cellular protein metabolic processGO:0032268520.013
neurotransmitter transportGO:000683620.013
regulation of stem cell proliferationGO:007209120.013
peptidyl serine modificationGO:001820920.013
muscle tissue developmentGO:00605371100.013
homeostatic processGO:00425921420.013
fertilizationGO:000956630.013
sensory organ morphogenesisGO:00905962000.013
regulation of protein metabolic processGO:0051246560.013
embryonic heart tube morphogenesisGO:00031431080.013
transcription from rna polymerase ii promoterGO:0006366800.013
ear developmentGO:00435831270.013
adherens junction organizationGO:003433240.013
response to glucoseGO:000974930.013
negative regulation of catabolic processGO:000989530.013
microtubule organizing center organizationGO:003102310.013
regulation of programmed cell deathGO:00430671010.013
female gonad developmentGO:000858540.013
positive regulation of response to stimulusGO:0048584800.013
determination of heart left right asymmetryGO:00613711170.013
glucose homeostasisGO:004259310.013
regulation of chromosome segregationGO:005198310.013
positive regulation of cellular metabolic processGO:0031325940.013
regulation of i kappab kinase nf kappab signalingGO:004312240.013
cellular response to lipopolysaccharideGO:007122230.013
regulation of oocyte developmentGO:006028130.013
regulation of protein bindingGO:004339330.012
ribosomal small subunit biogenesisGO:004227420.012
positive regulation of lipid metabolic processGO:004583410.012
rna modificationGO:000945120.012
toll like receptor signaling pathwayGO:000222440.012
specification of axis polarityGO:006500140.012
regulation of response to biotic stimulusGO:000283120.012
gastrulation with mouth forming secondGO:0001702440.012
regulation of catalytic activityGO:0050790550.012
mitotic cell cycle processGO:1903047480.012
bmp signaling pathwayGO:0030509520.012
activation of mapk activityGO:000018730.012
regulation of cell projection assemblyGO:006049140.012
leukocyte differentiationGO:0002521250.012
regulation of inflammatory responseGO:005072720.012
positive regulation of jnk cascadeGO:004633030.012
lamellipodium organizationGO:009758110.012
regulation of cell deathGO:00109411030.012
regulation of rho protein signal transductionGO:003502320.012
somitogenesisGO:0001756870.012
positive regulation of immune effector processGO:000269930.012
regulation of bmp signaling pathwayGO:0030510390.012
cellular response to molecule of bacterial originGO:007121930.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
positive regulation of muscle cell differentiationGO:005114910.012
epithelial cell developmentGO:0002064420.012
brain developmentGO:00074202930.012
camera type eye developmentGO:00430102220.012
negative regulation of myeloid cell differentiationGO:004563810.012
hepaticobiliary system developmentGO:0061008980.012
cellular lipid metabolic processGO:0044255360.012
cellular response to organic substanceGO:00713101050.012
regulation of organelle assemblyGO:190211540.012
cellular response to oxygen levelsGO:007145310.012
lamellipodium assemblyGO:003003210.012
intracellular mrna localizationGO:000829810.012
leukocyte proliferationGO:007066110.012
positive regulation of macromolecule metabolic processGO:0010604930.012
head developmentGO:00603223030.012
mitotic dna integrity checkpointGO:004477440.012
response to xenobiotic stimulusGO:0009410450.012
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.012
rna 3 end processingGO:003112320.012
mitochondrial transportGO:000683920.011
negative regulation of wnt signaling pathwayGO:0030178300.011
response to monosaccharideGO:003428430.011
positive regulation of signal transductionGO:0009967560.011
regulation of transcription from rna polymerase ii promoterGO:00063571140.011
peptidyl lysine acetylationGO:001839420.011
negative regulation of nuclear divisionGO:005178430.011
regulation of endothelial cell proliferationGO:000193610.011
taxisGO:00423301090.011
stem cell developmentGO:0048864820.011
positive regulation of camp metabolic processGO:003081620.011
regulation of wnt signaling pathwayGO:0030111530.011
astrocyte differentiationGO:004870810.011
ras protein signal transductionGO:000726570.011
macromolecular complex subunit organizationGO:0043933740.011
development of primary female sexual characteristicsGO:004654540.011
response to uvGO:000941130.011
regulation of cell developmentGO:00602841000.011
heart contractionGO:0060047710.011
cell agingGO:000756920.011
regulation of jak stat cascadeGO:004642530.011
negative regulation of cellular metabolic processGO:0031324770.011
regulation of cell morphogenesisGO:0022604420.011
negative regulation of multi organism processGO:004390130.011
pigmentationGO:0043473850.011
cellular amide metabolic processGO:004360340.011
production of molecular mediator of immune responseGO:000244020.011
regulation of neural precursor cell proliferationGO:200017730.011
single fertilizationGO:000733830.011
oocyte maturationGO:000155640.011

cops6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.031
nervous system diseaseDOID:86300.022
eye and adnexa diseaseDOID:149200.016
eye diseaseDOID:561400.016
sensory system diseaseDOID:005015500.016
inherited metabolic disorderDOID:65500.015
disease of metabolismDOID:001466700.015
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.013
organ system cancerDOID:005068600.013