Danio rerio

0 known processes

cops4

COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)

(Aliases: wu:fc90c08,zgc:77137,fc90c08)

cops4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.491
Worm
modification dependent protein catabolic processGO:001994130.183
Fly
gene expressionGO:00104672520.179
Fly
cellular protein catabolic processGO:004425740.167
Fly
modification dependent macromolecule catabolic processGO:004363230.154
Fly
nucleic acid metabolic processGO:00903042440.146
cellular nitrogen compound metabolic processGO:00346412900.109
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.106
Fly
dna templated transcription initiationGO:000635210.105
cellular macromolecule biosynthetic processGO:00346452240.103
cellular macromolecule metabolic processGO:00442603910.096
Human Fly
embryo development ending in birth or egg hatchingGO:00097922710.088
Worm
ubiquitin dependent protein catabolic processGO:000651130.088
Fly
nitrogen compound metabolic processGO:00068073190.081
heterocycle metabolic processGO:00464832900.072
agingGO:000756820.072
rna metabolic processGO:00160702190.072
organic cyclic compound biosynthetic processGO:19013622230.070
proteasomal protein catabolic processGO:001049820.063
Fly
nucleobase containing compound metabolic processGO:00061392740.062
macromolecule biosynthetic processGO:00090592270.060
positive regulation of cellular catabolic processGO:003133130.059
autophagyGO:000691440.056
biosynthetic processGO:00090582940.056
rna biosynthetic processGO:00327741810.055
heterocycle biosynthetic processGO:00181302150.055
regulation of gene expressionGO:00104682650.054
Fly
organic cyclic compound metabolic processGO:19013603010.052
zymogen activationGO:003163830.052
response to stressGO:00069502630.052
Fly
protein localization to nucleusGO:003450430.051
meiotic cell cycle processGO:190304630.050
regulation of cellular macromolecule biosynthetic processGO:20001122220.048
cellular protein metabolic processGO:00442671290.048
Human Fly
transcription dna templatedGO:00063511810.047
membrane fusionGO:006102520.047
regulation of nitrogen compound metabolic processGO:00511712510.047
single organism organelle organizationGO:19025891990.045
protein metabolic processGO:00195381830.045
Human Fly
aromatic compound biosynthetic processGO:00194382170.044
regulation of nucleic acid templated transcriptionGO:19035062130.044
regulation of biological qualityGO:00650082630.042
Fly
nuclear transportGO:005116940.040
proteolysis involved in cellular protein catabolic processGO:005160330.040
Fly
cellular transition metal ion homeostasisGO:004691630.040
meiotic nuclear divisionGO:000712640.039
nucleic acid templated transcriptionGO:00976591810.039
nucleobase containing compound biosynthetic processGO:00346542050.038
cell deathGO:00082191210.037
cellular response to external stimulusGO:007149620.037
transcription from rna polymerase ii promoterGO:0006366800.037
deathGO:00162651210.036
cellular nitrogen compound biosynthetic processGO:00442712180.036
multicellular organism growthGO:003526440.036
regulation of macromolecule metabolic processGO:00602553170.035
Fly
protein secretionGO:000930610.034
regulation of cellular metabolic processGO:00313233200.034
Fly
regulation of nucleobase containing compound metabolic processGO:00192192500.034
nucleoside monophosphate catabolic processGO:000912540.034
camera type eye developmentGO:00430102220.032
regulation of primary metabolic processGO:00800903110.032
Fly
amine metabolic processGO:000930820.032
protein complex disassemblyGO:004324110.031
negative regulation of protein phosphorylationGO:000193340.031
regulation of cellular amine metabolic processGO:003323800.031
cellular aromatic compound metabolic processGO:00067252950.031
regulation of protein catabolic processGO:004217610.031
Fly
internal protein amino acid acetylationGO:000647520.031
regulation of cellular biosynthetic processGO:00313262450.030
lipid storageGO:001991510.030
protein targeting to nucleusGO:004474430.030
nucleocytoplasmic transportGO:000691340.030
purine nucleoside monophosphate catabolic processGO:000912840.030
protein acetylationGO:000647320.029
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.029
regulation of cellular amino acid metabolic processGO:000652100.028
locomotionGO:00400113130.028
Worm
cellular component disassemblyGO:002241110.028
nuclear importGO:005117030.028
positive regulation of catabolic processGO:000989640.028
regulation of establishment of protein localizationGO:007020140.027
regulation of transcription dna templatedGO:00063552130.027
establishment of protein localization to organelleGO:007259440.027
positive regulation of cellular component biogenesisGO:004408930.027
cellular response to extracellular stimulusGO:003166820.026
positive regulation of nitrogen compound metabolic processGO:0051173690.026
cellular biosynthetic processGO:00442492860.026
organonitrogen compound metabolic processGO:1901564740.026
skeletal system developmentGO:00015011810.026
organelle fusionGO:004828430.025
single organism membrane fusionGO:004480120.025
regulation of transcription from rna polymerase ii promoterGO:00063571140.025
regulation of rna biosynthetic processGO:20011412130.024
regulation of nucleoside metabolic processGO:000911820.024
regulation of cellular protein catabolic processGO:190336210.024
Fly
cellular component biogenesisGO:00440851780.024
rrna catabolic processGO:001607510.024
response to other organismGO:0051707970.024
organelle organizationGO:00069962270.024
gtp metabolic processGO:004603940.024
positive regulation of protein complex assemblyGO:003133420.024
response to external biotic stimulusGO:0043207970.023
iron ion homeostasisGO:005507240.023
regulation of metabolic processGO:00192223590.023
Fly
regulation of dna templated transcription elongationGO:003278430.023
phagocytosisGO:000690930.023
microtubule cytoskeleton organization involved in mitosisGO:190285010.023
double strand break repairGO:000630230.022
mitochondrion organizationGO:000700540.022
protein import into nucleusGO:000660630.022
dna biosynthetic processGO:007189730.022
regulation of intracellular protein transportGO:003315730.022
response to chemicalGO:00422213200.022
single organism metabolic processGO:00447102170.022
single organism nuclear importGO:190259330.022
purine ribonucleoside monophosphate catabolic processGO:000916940.022
cellular amino acid metabolic processGO:000652070.022
positive regulation of rna biosynthetic processGO:1902680570.022
regulation of protein complex assemblyGO:004325430.022
regulation of protein transportGO:005122330.021
macromolecular complex disassemblyGO:003298410.021
regulation of biosynthetic processGO:00098892500.021
neuroblast proliferationGO:000740520.021
glucose homeostasisGO:004259310.021
regulation of macromolecule biosynthetic processGO:00105562250.021
organic substance biosynthetic processGO:19015762890.021
guanosine containing compound catabolic processGO:190106920.021
cellular amine metabolic processGO:004410620.021
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.020
Fly
protein modification processGO:00362111000.020
Human Fly
peptide transportGO:001583310.020
regulation of developmental processGO:00507932470.020
cellular ketone metabolic processGO:0042180110.020
protein stabilizationGO:005082120.020
Fly
positive regulation of nucleobase containing compound metabolic processGO:0045935690.020
programmed cell deathGO:00125011190.020
ribonucleoside monophosphate catabolic processGO:000915840.020
macromolecule modificationGO:00434121110.020
Human Fly
stem cell divisionGO:001714510.020
positive regulation of secretionGO:005104710.020
ncrna catabolic processGO:003466110.020
gtp catabolic processGO:000618420.020
protein acylationGO:004354330.019
organic acid metabolic processGO:0006082310.019
cellular response to nutrient levelsGO:003166920.019
carbohydrate homeostasisGO:003350010.019
regulation of protein localization to nucleusGO:190018020.019
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.019
protein importGO:001703830.019
regulation of rna metabolic processGO:00512522240.019
regulation of response to stimulusGO:00485832690.019
regulation of cytoplasmic transportGO:190364940.019
regulation of cellular ketone metabolic processGO:001056570.019
positive regulation of cell divisionGO:005178120.019
regulation of bindingGO:005109830.019
stem cell proliferationGO:007208940.018
synaptic growth at neuromuscular junctionGO:005112420.018
mitotic dna integrity checkpointGO:004477440.018
Fly
response to organic substanceGO:00100331530.018
positive regulation of transcription dna templatedGO:0045893570.018
single organism localizationGO:19025782250.018
regulation of cytokine productionGO:000181730.018
positive regulation of nucleic acid templated transcriptionGO:1903508570.018
atp catabolic processGO:000620040.017
negative regulation of biological processGO:00485193040.017
Fly
apoptotic processGO:00069151160.017
regulation of multicellular organismal processGO:00512392770.017
regulation of cell cycleGO:0051726520.017
Fly
negative regulation of chromosome organizationGO:200125110.017
positive regulation of cellular biosynthetic processGO:0031328680.017
guanosine containing compound metabolic processGO:190106840.017
growthGO:00400071740.017
regulation of cell projection assemblyGO:006049140.017
positive regulation of transportGO:005105020.017
maintenance of locationGO:005123540.016
regulation of protein modification by small protein conjugation or removalGO:190332030.016
regulation of blood vessel sizeGO:005088020.016
oxoacid metabolic processGO:0043436310.016
response to external stimulusGO:00096052640.016
adult behaviorGO:003053420.016
cellular response to stressGO:0033554620.016
Fly
membrane invaginationGO:001032410.016
regulation of multicellular organism growthGO:004001440.016
protein dephosphorylationGO:000647030.016
positive regulation of biological processGO:00485182530.016
internal peptidyl lysine acetylationGO:001839320.016
organic substance catabolic processGO:1901575280.016
Fly
dna templated transcription elongationGO:000635430.016
positive regulation of metabolic processGO:00098931080.016
transportGO:00068102200.016
negative regulation of signal transductionGO:0009968940.015
negative regulation of protein kinase activityGO:000646940.015
small molecule metabolic processGO:0044281770.015
sensory organ developmentGO:00074233930.015
Fly
regulation of purine nucleotide catabolic processGO:003312120.015
retina development in camera type eyeGO:00600411460.015
response to monosaccharideGO:003428430.015
multicellular organismal metabolic processGO:004423620.015
chordate embryonic developmentGO:00430092710.015
liver developmentGO:0001889960.014
carboxylic acid metabolic processGO:0019752220.014
cell migrationGO:00164772370.014
neurotransmitter transportGO:000683620.014
regulation of i kappab kinase nf kappab signalingGO:004312240.014
nucleic acid transportGO:005065720.014
cell motilityGO:00488702440.014
spindle assemblyGO:005122520.014
digestive system developmentGO:00551232890.014
symbiosis encompassing mutualism through parasitismGO:004440340.014
regulation of nucleocytoplasmic transportGO:004682220.014
meiotic chromosome segregationGO:004513230.014
peptidyl lysine acetylationGO:001839420.014
positive regulation of cell cycleGO:004578730.014
regulation of reproductive processGO:200024140.014
regulation of nucleotide catabolic processGO:003081120.014
cellular response to chemical stimulusGO:00708871570.014
regulation of inflammatory responseGO:005072720.014
positive regulation of dna templated transcription elongationGO:003278610.013
positive regulation of macromolecule biosynthetic processGO:0010557590.013
negative regulation of cellular metabolic processGO:0031324770.013
Fly
negative regulation of cellular processGO:00485232830.013
Fly
cellular component movementGO:00069283350.013
phosphorus metabolic processGO:00067931090.013
positive regulation of cellular amine metabolic processGO:003324000.013
erk1 and erk2 cascadeGO:007037140.013
regulation of protein targetingGO:190353320.013
cytoskeleton dependent cytokinesisGO:006164030.013
positive regulation of nucleoside metabolic processGO:004597910.013
regulation of blood pressureGO:000821710.013
extrinsic apoptotic signaling pathwayGO:009719130.013
central nervous system developmentGO:00074173870.013
regulation of tube sizeGO:003515020.013
positive regulation of gene expressionGO:0010628710.013
multi organism processGO:00517041340.013
ovulation cycleGO:004269820.013
regulation of wound healingGO:006104120.012
positive regulation of cytokine productionGO:000181920.012
regulation of organ growthGO:004662030.012
digestive tract developmentGO:00485652650.012
pole plasm assemblyGO:000731540.012
hormone secretionGO:004687920.012
i kappab kinase nf kappab signalingGO:000724940.012
head developmentGO:00603223030.012
germ line stem cell divisionGO:004207810.012
positive regulation of cell activationGO:005086710.012
pronephros developmentGO:0048793690.012
cell cycleGO:0007049930.012
Worm Fly
regulation of epithelial cell proliferationGO:005067830.012
protein complex localizationGO:003150310.012
regulation of protein import into nucleusGO:004230620.012
peptidyl serine phosphorylationGO:001810510.012
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.012
lipid catabolic processGO:001604240.012
cellular response to topologically incorrect proteinGO:003596720.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
negative regulation of cell communicationGO:0010648960.012
mitotic nuclear divisionGO:0007067180.012
mitotic g2 dna damage checkpointGO:000709530.012
Fly
negative regulation of kinase activityGO:003367340.012
regulation of chromosome segregationGO:005198310.012
exocytosisGO:000688710.012
negative regulation of catabolic processGO:000989530.012
Fly
immune system processGO:00023762410.012
mononuclear cell proliferationGO:003294310.012
cellular component morphogenesisGO:00329893360.012
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.012
lymphocyte proliferationGO:004665110.011
ribose phosphate metabolic processGO:0019693270.011
regulation of cellular protein metabolic processGO:0032268520.011
Fly
response to biotic stimulusGO:0009607970.011
regulation of reactive oxygen species metabolic processGO:200037720.011
single fertilizationGO:000733830.011
regulation of synapse organizationGO:005080730.011
response to topologically incorrect proteinGO:003596620.011
regulation of postsynaptic membrane potentialGO:006007810.011
golgi vesicle transportGO:004819330.011
action potentialGO:0001508190.011
ovulation cycle processGO:002260220.011
regulation of multicellular organismal developmentGO:20000262230.011
female sex differentiationGO:004666040.011
positive regulation of lipid metabolic processGO:004583410.011
regulation of protein ubiquitinationGO:003139630.011
response to glucoseGO:000974930.011
negative regulation of gene expressionGO:0010629650.011
Fly
response to hexoseGO:000974630.011
positive regulation of cellular metabolic processGO:0031325940.011
negative regulation of nitrogen compound metabolic processGO:0051172590.011
positive regulation of rna metabolic processGO:0051254590.011
peptidyl serine modificationGO:001820920.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280100.011
signal transductionGO:00071654550.011
cellular response to starvationGO:000926710.011
negative regulation of metabolic processGO:0009892860.011
Fly
chromosome organization involved in meiosisGO:007019210.011
cellular catabolic processGO:0044248270.011
Fly
regulation of cellular component organizationGO:0051128860.011
multicellular organismal macromolecule metabolic processGO:004425920.011
negative regulation of cytokine productionGO:000181810.011
regulation of cell deathGO:00109411030.011
regulation of stem cell proliferationGO:007209120.011
cell cycle g1 s phase transitionGO:004484310.011
cytoplasm organizationGO:000702840.011
urogenital system developmentGO:0001655970.011
b cell activationGO:004211320.011
localization of cellGO:00516742440.011
establishment of localizationGO:00512342440.010
mitotic cell cycleGO:0000278640.010
Fly
positive regulation of immune effector processGO:000269930.010
interspecies interaction between organismsGO:004441940.010
tissue remodelingGO:004877140.010
regulation of stem cell differentiationGO:200073640.010
protein modification by small protein removalGO:007064610.010
Human Fly
nucleotide metabolic processGO:0009117280.010
er to golgi vesicle mediated transportGO:000688810.010
regulation of synaptic growth at neuromuscular junctionGO:000858210.010
rna 3 end processingGO:003112320.010
positive regulation of cellular amino acid metabolic processGO:004576400.010
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.010
system processGO:00030081850.010
endoplasmic reticulum unfolded protein responseGO:003096820.010

cops4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.037
cancerDOID:16200.023
organ system cancerDOID:005068600.023
disease of cellular proliferationDOID:1456600.023
nervous system diseaseDOID:86300.018
disease of metabolismDOID:001466700.015