Danio rerio

22 known processes

pdcd10a

programmed cell death 10a

(Aliases: MGC65826,pdcd10,zgc:65826)

pdcd10a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
central nervous system developmentGO:00074173870.149
larval developmentGO:000216420.141
agingGO:000756820.120
signal transductionGO:00071654550.117
Human
head developmentGO:00603223030.115
embryo development ending in birth or egg hatchingGO:00097922710.110
organic cyclic compound metabolic processGO:19013603010.091
immune system processGO:00023762410.091
ubiquitin dependent protein catabolic processGO:000651130.091
brain developmentGO:00074202930.084
regulation of multicellular organismal processGO:00512392770.081
proteolysis involved in cellular protein catabolic processGO:005160330.076
response to organic substanceGO:00100331530.075
regulation of signalingGO:00230512350.074
Human
cellular macromolecule metabolic processGO:00442603910.074
Human
morphogenesis of an epitheliumGO:00020093330.073
cellular protein catabolic processGO:004425740.071
cellular protein metabolic processGO:00442671290.069
Human
positive regulation of transportGO:005105020.068
cell morphogenesisGO:00009022890.063
protein metabolic processGO:00195381830.062
Human
response to chemicalGO:00422213200.060
modification dependent protein catabolic processGO:001994130.059
establishment of protein localization to organelleGO:007259440.059
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.057
nucleobase containing compound metabolic processGO:00061392740.057
cellular component movementGO:00069283350.056
heterocycle metabolic processGO:00464832900.055
ion homeostasisGO:0050801410.054
vasculature developmentGO:00019442780.052
cellular component morphogenesisGO:00329893360.051
cellular aromatic compound metabolic processGO:00067252950.051
modification dependent macromolecule catabolic processGO:004363230.051
tube morphogenesisGO:00352393490.051
intracellular signal transductionGO:0035556850.051
Human
cell projection organizationGO:00300302840.051
lateral inhibitionGO:004633110.050
cellular response to external stimulusGO:007149620.050
protein secretionGO:000930610.049
negative regulation of secretionGO:005104820.049
maintenance of locationGO:005123540.048
nitrogen compound metabolic processGO:00068073190.048
regulation of biological qualityGO:00650082630.047
transportGO:00068102200.047
cognitionGO:005089010.046
positive regulation of catabolic processGO:000989640.046
negative regulation of biological processGO:00485193040.045
Human
phagocytosisGO:000690930.045
positive regulation of secretion by cellGO:190353210.042
cellular response to chemical stimulusGO:00708871570.042
generation of neuronsGO:00486993850.042
single organism organelle organizationGO:19025891990.042
cell surface receptor signaling pathwayGO:00071663250.042
digestive system developmentGO:00551232890.042
regulation of developmental processGO:00507932470.041
regulation of cell communicationGO:00106462320.041
Human
single organism metabolic processGO:00447102170.041
Human
cation homeostasisGO:0055080330.041
organic substance transportGO:0071702580.040
cell morphogenesis involved in differentiationGO:00009041950.040
digestive tract morphogenesisGO:00485462310.039
chemical homeostasisGO:0048878490.039
regulation of signal transductionGO:00099662250.039
Human
cellular amine metabolic processGO:004410620.038
single organism nuclear importGO:190259330.038
response to drugGO:004249330.038
gastrulationGO:00073692080.038
regulation of response to stimulusGO:00485832690.037
Human
mitochondrion organizationGO:000700540.037
embryonic organ developmentGO:00485683810.037
synaptic vesicle localizationGO:009747910.037
regulation of cellular metabolic processGO:00313233200.036
Human
proteasomal protein catabolic processGO:001049820.036
synaptic vesicle transportGO:004848910.036
hemopoiesisGO:00300971830.036
single organism transportGO:00447652060.036
nucleic acid metabolic processGO:00903042440.036
cellular response to organic substanceGO:00713101050.035
establishment of localizationGO:00512342440.035
microtubule organizing center organizationGO:003102310.035
cellular nitrogen compound metabolic processGO:00346412900.035
programmed cell deathGO:00125011190.035
Human Worm
metal ion transportGO:0030001580.035
meiotic cell cycle processGO:190304630.035
regulation of protein complex assemblyGO:004325430.035
single organism localizationGO:19025782250.034
positive regulation of biological processGO:00485182530.034
Human
centrosome cycleGO:000709810.034
organic cyclic compound biosynthetic processGO:19013622230.034
protein polyubiquitinationGO:000020940.033
organelle organizationGO:00069962270.033
homeostatic processGO:00425921420.033
positive regulation of cellular processGO:00485222010.033
Human
regulation of bindingGO:005109830.033
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:004278710.032
positive regulation of erk1 and erk2 cascadeGO:007037420.032
regulation of protein ubiquitinationGO:003139630.032
immune system developmentGO:00025201910.032
regulation of transcription from rna polymerase ii promoter in response to oxidative stressGO:004361900.032
system processGO:00030081850.031
meiotic nuclear divisionGO:000712640.031
positive regulation of cell communicationGO:0010647560.031
Human
chordate embryonic developmentGO:00430092710.031
protein localization to nucleusGO:003450430.031
regulation of establishment of protein localizationGO:007020140.030
positive regulation of cellular catabolic processGO:003133130.030
cell part morphogenesisGO:00329902460.030
cell projection morphogenesisGO:00488582440.030
protein dephosphorylationGO:000647030.030
macromolecular complex subunit organizationGO:0043933740.030
peptidyl serine phosphorylationGO:001810510.030
protein importGO:001703830.030
regulation of cytokine productionGO:000181730.030
positive regulation of signalingGO:0023056560.029
Human
regulation of programmed cell deathGO:00430671010.029
Human
adult behaviorGO:003053420.029
regulation of cell shapeGO:000836010.028
regulation of synaptic growth at neuromuscular junctionGO:000858210.028
response to abiotic stimulusGO:00096281220.028
regulation of rna biosynthetic processGO:20011412130.028
regulation of nucleoside metabolic processGO:000911820.028
endocrine processGO:005088620.027
i kappab kinase nf kappab signalingGO:000724940.027
angiogenesisGO:00015251580.027
macromolecule modificationGO:00434121110.027
Human
cytoskeleton dependent cytokinesisGO:006164030.027
phosphorus metabolic processGO:00067931090.027
Human
meiotic chromosome segregationGO:004513230.027
meiosis iGO:000712710.026
negative regulation of protein phosphorylationGO:000193340.026
gtp catabolic processGO:000618420.026
regulation of protein catabolic processGO:004217610.026
gtp metabolic processGO:004603940.026
negative regulation of protein transportGO:005122430.026
autophagyGO:000691440.026
regulation of protein transportGO:005122330.025
sensory organ developmentGO:00074233930.025
deathGO:00162651210.025
Human Worm
cell migrationGO:00164772370.025
centrosome organizationGO:005129710.025
synaptic growth at neuromuscular junctionGO:005112420.025
regulation of protein modification by small protein conjugation or removalGO:190332030.024
organelle fusionGO:004828430.024
cation transportGO:0006812810.024
organic acid metabolic processGO:0006082310.024
regulation of erk1 and erk2 cascadeGO:007037240.024
response to antibioticGO:004667710.024
cytokinesisGO:000091030.024
regulation of metal ion transportGO:001095940.024
regulation of cell deathGO:00109411030.024
Human
peptide metabolic processGO:000651810.024
peptidyl serine modificationGO:001820920.024
neuron neuron synaptic transmissionGO:000727010.023
cellular protein modification processGO:00064641000.023
Human
neuroblast proliferationGO:000740520.023
protein import into nucleusGO:000660630.023
positive regulation of cell cycleGO:004578730.023
cell motilityGO:00488702440.023
blood vessel morphogenesisGO:00485142160.023
regulation of cell projection assemblyGO:006049140.023
negative regulation of programmed cell deathGO:0043069580.023
Human
cellular nitrogen compound biosynthetic processGO:00442712180.023
positive regulation of secretionGO:005104710.023
blood vessel developmentGO:00015682460.022
regulation of purine nucleotide catabolic processGO:003312120.022
cellular transition metal ion homeostasisGO:004691630.022
erk1 and erk2 cascadeGO:007037140.022
establishment of synaptic vesicle localizationGO:009748010.022
response to glucocorticoidGO:005138410.022
response to external stimulusGO:00096052640.022
cellular component disassemblyGO:002241110.022
cytoskeleton organizationGO:0007010960.022
regulation of phosphorus metabolic processGO:0051174430.022
Human
exocytosisGO:000688710.022
positive regulation of apoptotic signaling pathwayGO:200123510.022
regulation of oligodendrocyte differentiationGO:004871310.022
lipid storageGO:001991510.022
guanosine containing compound metabolic processGO:190106840.022
nucleocytoplasmic transportGO:000691340.021
positive regulation of small gtpase mediated signal transductionGO:005105710.021
regulation of synaptic plasticityGO:004816710.021
organelle assemblyGO:00709251100.021
regulation of primary metabolic processGO:00800903110.021
Human
regulation of nucleotide catabolic processGO:003081120.020
positive regulation of i kappab kinase nf kappab signalingGO:004312330.020
membrane fusionGO:006102520.020
aromatic compound biosynthetic processGO:00194382170.020
small molecule metabolic processGO:0044281770.020
guanosine containing compound catabolic processGO:190106920.020
cellular response to nutrient levelsGO:003166920.020
leukocyte proliferationGO:007066110.020
amine metabolic processGO:000930820.020
dicarboxylic acid transportGO:000683510.020
response to growth factorGO:0070848390.020
sodium ion transportGO:0006814240.020
phosphate containing compound metabolic processGO:00067961080.020
Human
regulation of gtp catabolic processGO:003312420.020
regulation of multicellular organism growthGO:004001440.020
positive regulation of cytokine productionGO:000181920.020
cellular localizationGO:0051641970.020
developmental growthGO:00485891660.019
regulation of cell differentiationGO:00455951420.019
regulation of reactive oxygen species metabolic processGO:200037720.019
metal ion homeostasisGO:0055065260.019
hematopoietic or lymphoid organ developmentGO:00485341910.019
locomotionGO:00400113130.019
negative regulation of cell deathGO:0060548600.019
Human
regulation of multicellular organismal developmentGO:20000262230.019
regulation of cell activationGO:005086510.019
cellular response to starvationGO:000926710.019
regulation of phosphate metabolic processGO:0019220430.019
Human
neuron developmentGO:00486662620.019
production of molecular mediator of immune responseGO:000244020.019
nuclear importGO:005117030.019
regulation of receptor activityGO:001046920.019
neuron projection morphogenesisGO:00488121610.019
regulation of endocrine processGO:004406020.019
positive regulation of protein complex assemblyGO:003133420.019
regulation of oxidative stress induced cell deathGO:190320120.018
ribonucleoside monophosphate catabolic processGO:000915840.018
axon developmentGO:00615641660.018
single organism membrane fusionGO:004480120.018
epithelial cell differentiationGO:00308551160.018
phosphorylationGO:0016310690.018
Human
neuron differentiationGO:00301823530.018
regulation of catalytic activityGO:0050790550.018
Human
regulation of molecular functionGO:0065009700.018
Human
regulation of cellular amine metabolic processGO:003323800.018
positive regulation of cytoskeleton organizationGO:005149530.018
regulation of i kappab kinase nf kappab signalingGO:004312240.018
regulation of metabolic processGO:00192223590.018
Human
glucose homeostasisGO:004259310.018
regulation of production of molecular mediator of immune responseGO:000270010.018
regulation of protein bindingGO:004339330.017
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.017
neuron projection developmentGO:00311751800.017
positive regulation of signal transductionGO:0009967560.017
Human
heart morphogenesisGO:00030071560.017
forebrain cell migrationGO:002188510.017
negative regulation of cellular processGO:00485232830.017
Human
behaviorGO:0007610740.017
multicellular organism growthGO:003526440.017
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.017
regulation of cellular ketone metabolic processGO:001056570.017
cell projection assemblyGO:0030031640.017
cell death in response to oxidative stressGO:003647320.017
cellular amide metabolic processGO:004360340.017
cellular component biogenesisGO:00440851780.017
b cell activationGO:004211320.016
peptide transportGO:001583310.016
convergent extensionGO:00600261180.016
nucleic acid templated transcriptionGO:00976591810.016
positive regulation of response to stimulusGO:0048584800.016
Human
negative regulation of cytoplasmic transportGO:190365020.016
negative regulation of response to cytokine stimulusGO:006076120.016
stem cell divisionGO:001714510.016
membrane invaginationGO:001032410.016
organic substance biosynthetic processGO:19015762890.016
regulation of filopodium assemblyGO:005148920.016
regulation of macromolecule metabolic processGO:00602553170.016
Human
regulation of cellular macromolecule biosynthetic processGO:20001122220.016
apoptotic processGO:00069151160.016
Human Worm
cellular amino acid metabolic processGO:000652070.016
cellular monovalent inorganic cation homeostasisGO:003000420.016
regulation of rho protein signal transductionGO:003502320.016
regulation of apoptotic processGO:0042981980.016
Human
tissue remodelingGO:004877140.016
negative regulation of signalingGO:0023057960.016
nuclear migrationGO:000709730.016
regulation of intracellular protein transportGO:003315730.016
positive regulation of jnk cascadeGO:004633030.016
regulation of response to oxidative stressGO:190288220.016
regulation of cellular protein catabolic processGO:190336210.016
cellular component assemblyGO:00226071700.015
skeletal system morphogenesisGO:00487051020.015
cellular respirationGO:004533330.015
actin polymerization or depolymerizationGO:000815420.015
macroautophagyGO:001623610.015
response to stressGO:00069502630.015
fertilizationGO:000956630.015
post embryonic organ developmentGO:004856940.015
cell cycle processGO:0022402530.015
protein targeting to nucleusGO:004474430.015
neurological system processGO:0050877620.015
regulation of cellular amino acid metabolic processGO:000652100.015
small gtpase mediated signal transductionGO:000726480.015
macromolecule biosynthetic processGO:00090592270.015
regulation of transcription dna templatedGO:00063552130.015
protein k48 linked ubiquitinationGO:007093610.015
dorsal ventral neural tube patterningGO:002190410.015
post embryonic morphogenesisGO:000988640.015
dna biosynthetic processGO:007189730.015
regulation of wound healingGO:006104120.015
positive regulation of cellular component biogenesisGO:004408930.015
protein acylationGO:004354330.015
myeloid cell differentiationGO:0030099860.015
mitochondrial transportGO:000683920.015
positive regulation of stress activated mapk cascadeGO:003287430.015
protein polymerizationGO:005125840.014
regulation of protein targetingGO:190353320.014
response to other organismGO:0051707970.014
atp catabolic processGO:000620040.014
response to decreased oxygen levelsGO:0036293250.014
nuclear transportGO:005116940.014
sodium ion transmembrane transportGO:0035725210.014
regulation of response to cytokine stimulusGO:006075930.014
oxoacid metabolic processGO:0043436310.014
mesenchymal cell developmentGO:0014031780.014
transcription dna templatedGO:00063511810.014
cellular cation homeostasisGO:0030003170.014
response to endogenous stimulusGO:0009719830.014
lymphocyte homeostasisGO:000226010.014
negative regulation of secretion by cellGO:190353120.014
convergent extension involved in gastrulationGO:0060027710.014
multi organism processGO:00517041340.014
purine ribonucleoside monophosphate catabolic processGO:000916940.014
post golgi vesicle mediated transportGO:000689210.014
regulation of intracellular signal transductionGO:1902531570.013
Human
eye developmentGO:00016542770.013
response to hypoxiaGO:0001666250.013
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
purine nucleoside monophosphate catabolic processGO:000912840.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
chromosome organization involved in meiosisGO:007019210.013
regulation of nitrogen compound metabolic processGO:00511712510.013
macromolecule localizationGO:0033036540.013
regulation of cellular response to oxidative stressGO:190040720.013
positive regulation of immune effector processGO:000269930.013
response to oxygen levelsGO:0070482250.013
organonitrogen compound metabolic processGO:1901564740.013
positive regulation of nucleoside metabolic processGO:004597910.013
meiosis iiGO:000713510.013
negative regulation of signal transductionGO:0009968940.013
protein localizationGO:0008104400.013
regulation of nucleic acid templated transcriptionGO:19035062130.013
protein phosphorylationGO:0006468470.013
Human
protein complex subunit organizationGO:0071822460.013
nucleobase containing compound biosynthetic processGO:00346542050.013
regulation of protein polymerizationGO:003227120.013
stem cell proliferationGO:007208940.013
positive regulation of cellular amine metabolic processGO:003324000.013
positive regulation of neuron deathGO:190121610.013
heart developmentGO:00075073130.013
growthGO:00400071740.012
proteolysisGO:0006508380.012
cellular response to extracellular stimulusGO:003166820.012
neuron deathGO:0070997210.012
response to woundingGO:00096111160.012
heterocycle biosynthetic processGO:00181302150.012
cellular ketone metabolic processGO:0042180110.012
regulation of protein metabolic processGO:0051246560.012
Human
response to salt stressGO:0009651100.012
response to topologically incorrect proteinGO:003596620.012
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217520.012
ion transportGO:00068111140.012
phagocytosis engulfmentGO:000691110.012
regulation of cytokine mediated signaling pathwayGO:000195930.012
divalent inorganic cation homeostasisGO:0072507220.012
regulation of lipid transportGO:003236840.012
cell agingGO:000756920.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
carboxylic acid metabolic processGO:0019752220.012
regulation of cellular component organizationGO:0051128860.012
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.012
protein modification processGO:00362111000.012
Human
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217620.012
microtubule based processGO:0007017600.012
defense responseGO:0006952470.012
retina development in camera type eyeGO:00600411460.012
motor neuron axon guidanceGO:0008045230.012
cellular response to decreased oxygen levelsGO:003629410.012
regulation of cytoplasmic transportGO:190364940.012
regulation of anatomical structure morphogenesisGO:00226031300.012
specification of axis polarityGO:006500140.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
cellular response to oxygen levelsGO:007145310.012
endocardial cushion morphogenesisGO:000320330.012
transcription from rna polymerase ii promoterGO:0006366800.011
peptidyl tyrosine dephosphorylationGO:003533510.011
leukocyte homeostasisGO:000177620.011
post embryonic organ morphogenesisGO:004856310.011
positive regulation of ras protein signal transductionGO:004657910.011
regulation of dendrite developmentGO:005077330.011
regulation of response to biotic stimulusGO:000283120.011
adherens junction organizationGO:003433240.011
positive regulation of macromolecule metabolic processGO:0010604930.011
Human
positive regulation of cell activationGO:005086710.011
iron ion homeostasisGO:005507240.011
regulation of gtpase activityGO:004308720.011
anterior posterior pattern specificationGO:00099521520.011
regulation of synapse assemblyGO:005196330.011
negative regulation of cell communicationGO:0010648960.011
negative regulation of protein complex assemblyGO:003133310.011
regulation of blood pressureGO:000821710.011
protein complex disassemblyGO:004324110.011
cellular macromolecule biosynthetic processGO:00346452240.011
nucleoside monophosphate catabolic processGO:000912540.011
neurotransmitter transportGO:000683620.011
negative regulation of stem cell differentiationGO:200073720.011
homeostasis of number of cellsGO:0048872620.011
regulation of hormone secretionGO:004688320.011
hematopoietic progenitor cell differentiationGO:0002244230.011
rna metabolic processGO:00160702190.011
neurotransmitter secretionGO:000726920.011
negative regulation of epithelial cell proliferationGO:005068010.011
cellular response to topologically incorrect proteinGO:003596720.011
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.011
negative regulation of cellular catabolic processGO:003133030.011
cellular response to hypoxiaGO:007145610.011
monovalent inorganic cation transportGO:0015672420.011
hormone transportGO:000991420.011
regulation of glucose importGO:004632410.011
protein complex assemblyGO:0006461300.011
regulation of epithelial cell proliferationGO:005067830.010
positive regulation of blood circulationGO:190352420.010
macromolecular complex disassemblyGO:003298410.010
regulation of extrinsic apoptotic signaling pathwayGO:200123630.010
actin filament based processGO:0030029640.010
brain morphogenesisGO:0048854180.010
skeletal system developmentGO:00015011810.010
transmembrane transportGO:00550851200.010
wnt signaling pathwayGO:0016055800.010
detection of abiotic stimulusGO:0009582240.010
cellular response to reactive oxygen speciesGO:003461420.010
locomotory behaviorGO:0007626340.010
biosynthetic processGO:00090582940.010
carbohydrate homeostasisGO:003350010.010
cell cycle g1 s phase transitionGO:004484310.010
neural tube patterningGO:0021532330.010
axonogenesisGO:00074091520.010

pdcd10a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.055
disease of metabolismDOID:001466700.055
disease of anatomical entityDOID:700.030
lysosomal storage diseaseDOID:321100.025
lipid storage diseaseDOID:945500.025
nervous system diseaseDOID:86300.025
musculoskeletal system diseaseDOID:1700.021
muscular diseaseDOID:008000000.021
myopathyDOID:42300.020
cardiovascular system diseaseDOID:128700.020
heart diseaseDOID:11400.020
muscle tissue diseaseDOID:6600.020
cardiomyopathyDOID:005070000.020
disease of cellular proliferationDOID:1456600.020
organ system cancerDOID:005068600.020
cancerDOID:16200.020
intrinsic cardiomyopathyDOID:006003600.011
central nervous system diseaseDOID:33100.010
neurodegenerative diseaseDOID:128900.010
gastrointestinal system cancerDOID:311900.010