Danio rerio

0 known processes

ptk2.2

protein tyrosine kinase 2b

(Aliases: fak1b,ptk2b,si:ch1073-355e8.1)

ptk2.2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to chemicalGO:00422213200.074
negative regulation of biological processGO:00485193040.074
positive regulation of biological processGO:00485182530.072
cell surface receptor signaling pathwayGO:00071663250.068
response to external stimulusGO:00096052640.064
chordate embryonic developmentGO:00430092710.061
cell motilityGO:00488702440.060
regulation of macromolecule metabolic processGO:00602553170.060
positive regulation of cellular processGO:00485222010.058
agingGO:000756820.058
multicellular organism growthGO:003526440.056
regulation of metabolic processGO:00192223590.053
single organism organelle organizationGO:19025891990.053
cell projection morphogenesisGO:00488582440.051
locomotionGO:00400113130.050
regulation of primary metabolic processGO:00800903110.050
wnt signaling pathwayGO:0016055800.048
embryonic organ morphogenesisGO:00485622740.047
cellular response to chemical stimulusGO:00708871570.047
cellular component movementGO:00069283350.046
anterior posterior pattern specificationGO:00099521520.046
heart developmentGO:00075073130.045
leukocyte proliferationGO:007066110.044
regulation of protein transportGO:005122330.044
macromolecule biosynthetic processGO:00090592270.044
maintenance of locationGO:005123540.044
nephron tubule morphogenesisGO:007207810.043
extrinsic apoptotic signaling pathwayGO:009719130.043
cell morphogenesisGO:00009022890.043
negative regulation of synapse assemblyGO:005196420.043
regulation of epithelial cell proliferationGO:005067830.042
cellular macromolecule metabolic processGO:00442603910.041
positive regulation of cell cycleGO:004578730.041
morphogenesis of an epitheliumGO:00020093330.040
response to drugGO:004249330.039
regulation of multicellular organism growthGO:004001440.039
vasculature developmentGO:00019442780.039
regulation of multicellular organismal processGO:00512392770.038
gene expressionGO:00104672520.038
cellular nitrogen compound metabolic processGO:00346412900.037
neuron developmentGO:00486662620.037
regulation of establishment of protein localizationGO:007020140.037
larval developmentGO:000216420.036
protein localization to nucleusGO:003450430.036
signal transductionGO:00071654550.035
regulation of nitrogen compound metabolic processGO:00511712510.035
positive regulation of transportGO:005105020.034
nitrogen compound metabolic processGO:00068073190.034
stem cell maintenanceGO:001982740.034
aromatic compound biosynthetic processGO:00194382170.034
regulation of cellular metabolic processGO:00313233200.034
localization of cellGO:00516742440.033
regulation of biomineral tissue developmentGO:007016720.033
establishment of localizationGO:00512342440.033
cellular component morphogenesisGO:00329893360.033
blood vessel morphogenesisGO:00485142160.032
nucleobase containing compound metabolic processGO:00061392740.032
regulation of bone mineralizationGO:003050020.032
regulation of response to stimulusGO:00485832690.031
embryonic organ developmentGO:00485683810.031
regulation of protein complex assemblyGO:004325430.031
stem cell proliferationGO:007208940.031
cellular carbohydrate metabolic processGO:004426240.031
organic cyclic compound biosynthetic processGO:19013622230.031
female sex differentiationGO:004666040.030
cellular aromatic compound metabolic processGO:00067252950.030
cellular component biogenesisGO:00440851780.030
taxisGO:00423301090.030
cellular response to external stimulusGO:007149620.030
blood vessel developmentGO:00015682460.030
cellular biosynthetic processGO:00442492860.030
negative regulation of response to stimulusGO:00485851040.030
regulation of signal transductionGO:00099662250.029
negative regulation of cellular processGO:00485232830.029
lipid storageGO:001991510.029
determination of bilateral symmetryGO:00098552040.029
amine metabolic processGO:000930820.029
organic cyclic compound metabolic processGO:19013603010.029
apoptotic process involved in developmentGO:190274220.029
gastrulationGO:00073692080.028
transcription dna templatedGO:00063511810.028
renal system developmentGO:0072001940.028
regulation of cellular macromolecule biosynthetic processGO:20001122220.028
rhombomere 5 developmentGO:002157140.028
regulation of cell communicationGO:00106462320.028
regulation of bindingGO:005109830.028
generation of neuronsGO:00486993850.028
embryo development ending in birth or egg hatchingGO:00097922710.028
regionalizationGO:00030022740.028
protein secretionGO:000930610.028
nucleic acid metabolic processGO:00903042440.028
sensory organ developmentGO:00074233930.028
regulation of cell activationGO:005086510.028
angiogenesisGO:00015251580.028
gland developmentGO:00487321430.028
regulation of biological qualityGO:00650082630.027
cell migrationGO:00164772370.027
cell morphogenesis involved in differentiationGO:00009041950.027
cell part morphogenesisGO:00329902460.027
developmental growthGO:00485891660.027
heterocycle biosynthetic processGO:00181302150.026
cellular amine metabolic processGO:004410620.026
specification of symmetryGO:00097992040.026
female gonad developmentGO:000858540.026
synaptic growth at neuromuscular junctionGO:005112420.026
heterocycle metabolic processGO:00464832900.026
positive regulation of cell adhesionGO:004578510.026
mononuclear cell proliferationGO:003294310.026
organic acid metabolic processGO:0006082310.026
cell projection organizationGO:00300302840.026
tube morphogenesisGO:00352393490.025
response to stressGO:00069502630.025
organelle organizationGO:00069962270.025
eye developmentGO:00016542770.025
lateral inhibitionGO:004633110.025
hormone transportGO:000991420.025
secondary metabolic processGO:001974830.025
positive regulation of nitrogen compound metabolic processGO:0051173690.025
regulation of reproductive processGO:200024140.025
oxoacid metabolic processGO:0043436310.025
positive regulation of secretionGO:005104710.024
regulation of cellular biosynthetic processGO:00313262450.024
transportGO:00068102200.024
carboxylic acid metabolic processGO:0019752220.024
somitogenesisGO:0001756870.024
protein metabolic processGO:00195381830.024
positive regulation of cellular component biogenesisGO:004408930.024
regulation of nucleobase containing compound metabolic processGO:00192192500.024
enzyme linked receptor protein signaling pathwayGO:00071671060.024
development of primary female sexual characteristicsGO:004654540.024
cellular response to organic substanceGO:00713101050.024
immune system processGO:00023762410.024
peptidyl serine phosphorylationGO:001810510.024
neuron projection morphogenesisGO:00488121610.024
wound healingGO:0042060900.024
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.024
protein import into nucleusGO:000660630.024
compound eye developmentGO:004874920.024
regulation of multicellular organismal developmentGO:20000262230.024
actin polymerization or depolymerizationGO:000815420.023
actin filament based processGO:0030029640.023
positive regulation of cellular amine metabolic processGO:003324000.023
regulation of transcription dna templatedGO:00063552130.023
urogenital system developmentGO:0001655970.023
negative regulation of protein phosphorylationGO:000193340.023
organic substance biosynthetic processGO:19015762890.023
synaptic target recognitionGO:000803910.023
guanosine containing compound metabolic processGO:190106840.023
organonitrogen compound metabolic processGO:1901564740.023
muscle cell differentiationGO:00426921390.023
response to vitaminGO:003327330.023
digestive system developmentGO:00551232890.023
gtp catabolic processGO:000618420.022
biosynthetic processGO:00090582940.022
establishment of protein localization to organelleGO:007259440.022
somite developmentGO:0061053960.022
positive regulation of protein complex assemblyGO:003133420.022
regulation of cellular amino acid metabolic processGO:000652100.022
regulation of developmental processGO:00507932470.022
regulation of gene expressionGO:00104682650.022
cellular ketone metabolic processGO:0042180110.022
determination of heart left right asymmetryGO:00613711170.022
cellular nitrogen compound biosynthetic processGO:00442712180.022
transcription from rna polymerase ii promoterGO:0006366800.022
cellular protein metabolic processGO:00442671290.022
neuron differentiationGO:00301823530.022
single organism metabolic processGO:00447102170.021
head developmentGO:00603223030.021
rna biosynthetic processGO:00327741810.021
nucleic acid templated transcriptionGO:00976591810.021
lymphocyte proliferationGO:004665110.021
regulation of macromolecule biosynthetic processGO:00105562250.021
neuroblast proliferationGO:000740520.021
regulation of signalingGO:00230512350.021
heart morphogenesisGO:00030071560.021
regulation of extrinsic apoptotic signaling pathwayGO:200123630.021
cellular response to starvationGO:000926710.021
regulation of cell shapeGO:000836010.021
regulation of wnt signaling pathwayGO:0030111530.021
sequestering of calcium ionGO:005120830.021
small molecule metabolic processGO:0044281770.021
positive regulation of cellular amino acid metabolic processGO:004576400.021
cellular protein modification processGO:00064641000.021
muscle structure developmentGO:00610611960.021
segmentationGO:0035282970.021
chemotaxisGO:00069351040.020
negative regulation of signalingGO:0023057960.020
protein polymerizationGO:005125840.020
epithelial cell differentiationGO:00308551160.020
positive regulation of macromolecule metabolic processGO:0010604930.020
positive regulation of cell activationGO:005086710.020
chemosensory behaviorGO:000763510.020
regulation of cellular amine metabolic processGO:003323800.020
kidney developmentGO:0001822920.020
intracellular signal transductionGO:0035556850.020
canonical wnt signaling pathwayGO:0060070480.020
cellular amino acid metabolic processGO:000652070.020
nucleocytoplasmic transportGO:000691340.020
energy reserve metabolic processGO:000611220.020
regulation of cell projection assemblyGO:006049140.020
regulation of rna metabolic processGO:00512522240.020
cellular response to extracellular stimulusGO:003166820.020
embryonic heart tube developmentGO:00350501330.019
cell morphogenesis involved in neuron differentiationGO:00486671630.019
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.019
macromolecule modificationGO:00434121110.019
regulation of dna replicationGO:000627530.019
gtp metabolic processGO:004603940.019
carbohydrate homeostasisGO:003350010.019
germ line stem cell maintenanceGO:003071820.019
positive regulation of stress activated mapk cascadeGO:003287430.019
adult behaviorGO:003053420.019
carbohydrate biosynthetic processGO:001605110.019
axon developmentGO:00615641660.019
regulation of protein localization to nucleusGO:190018020.019
heart loopingGO:0001947940.019
renal tubule morphogenesisGO:006133310.018
central nervous system developmentGO:00074173870.018
peptidyl serine modificationGO:001820920.018
camera type eye developmentGO:00430102220.018
macroautophagyGO:001623610.018
centrosome organizationGO:005129710.018
response to carbohydrateGO:000974330.018
muscle cell migrationGO:001481240.018
regulation of peptidyl tyrosine phosphorylationGO:005073010.018
regulation of blood vessel sizeGO:005088020.018
ear developmentGO:00435831270.018
rna metabolic processGO:00160702190.018
autophagyGO:000691440.018
nuclear importGO:005117030.018
regulation of nucleic acid templated transcriptionGO:19035062130.018
regulation of intracellular protein transportGO:003315730.018
regulation of carbohydrate metabolic processGO:000610940.018
cellular response to nutrient levelsGO:003166920.018
cellular localizationGO:0051641970.017
negative regulation of intracellular transportGO:003238730.017
single organism nuclear importGO:190259330.017
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.017
regulation of transcription from rna polymerase ii promoterGO:00063571140.017
nucleobase containing compound biosynthetic processGO:00346542050.017
axon guidanceGO:0007411860.017
response to woundingGO:00096111160.017
blood circulationGO:0008015870.017
cellular component assembly involved in morphogenesisGO:00109271070.017
sensory perception of chemical stimulusGO:000760630.017
regulation of cytokine productionGO:000181730.017
protein localization to plasma membraneGO:007265910.017
regulation of inflammatory responseGO:005072720.017
regulation of cytoplasmic transportGO:190364940.017
cell cycle arrestGO:000705010.017
protein targeting to nucleusGO:004474430.017
spinal cord developmentGO:0021510460.017
negative regulation of cytokine productionGO:000181810.017
protein importGO:001703830.017
nephron epithelium morphogenesisGO:007208810.017
embryonic heart tube morphogenesisGO:00031431080.017
regulation of rna biosynthetic processGO:20011412130.017
regulation of synapse assemblyGO:005196330.017
microtubule organizing center organizationGO:003102310.017
guanosine containing compound catabolic processGO:190106920.017
insulin like growth factor receptor signaling pathwayGO:004800940.016
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.016
regulation of biosynthetic processGO:00098892500.016
lamellipodium organizationGO:009758110.016
cartilage developmentGO:0051216960.016
regulation of stem cell differentiationGO:200073640.016
regulation of cellular ketone metabolic processGO:001056570.016
proteasomal protein catabolic processGO:001049820.016
positive regulation of cellular metabolic processGO:0031325940.016
dna templated transcription initiationGO:000635210.016
nuclear transportGO:005116940.016
response to nutrientGO:000758430.016
cell substrate junction assemblyGO:000704420.016
single organism transportGO:00447652060.016
regulation of protein metabolic processGO:0051246560.016
cellular modified amino acid metabolic processGO:000657530.016
negative chemotaxisGO:005091910.016
signal transduction in absence of ligandGO:003803410.016
growthGO:00400071740.016
brain developmentGO:00074202930.016
regulation of tube sizeGO:003515020.016
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.016
epithelial tube morphogenesisGO:00605621480.016
cellular response to endogenous stimulusGO:0071495680.015
regulation of sequestering of calcium ionGO:005128240.015
positive regulation of cytoskeleton organizationGO:005149530.015
alpha amino acid metabolic processGO:190160530.015
response to glucoseGO:000974930.015
response to corticosteroidGO:003196010.015
alcohol biosynthetic processGO:004616520.015
golgi vesicle transportGO:004819330.015
homeostatic processGO:00425921420.015
nuclear migrationGO:000709730.015
determination of left right symmetryGO:00073681790.015
positive regulation of map kinase activityGO:004340630.015
response to endogenous stimulusGO:0009719830.015
organelle fusionGO:004828430.015
gastrulation with mouth forming secondGO:0001702440.015
ovulation cycle processGO:002260220.015
regulation of synaptic growth at neuromuscular junctionGO:000858210.015
developmental programmed cell deathGO:001062340.015
positive regulation of reproductive processGO:200024320.015
stem cell divisionGO:001714510.014
circulatory system processGO:0003013870.014
regulation of autophagyGO:001050630.014
positive regulation of nucleoside metabolic processGO:004597910.014
negative regulation of heart contractionGO:004582220.014
negative regulation of wnt signaling pathwayGO:0030178300.014
regulation of localizationGO:00328791040.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.014
response to monosaccharideGO:003428430.014
olfactory lobe developmentGO:002198840.014
positive regulation of jnk cascadeGO:004633030.014
neuron projection developmentGO:00311751800.014
cilium morphogenesisGO:0060271850.014
negative regulation of ras protein signal transductionGO:004658010.014
long chain fatty acid metabolic processGO:000167610.014
protein complex localizationGO:003150310.014
exocytosisGO:000688710.014
regulation of hormone secretionGO:004688320.014
single organism membrane fusionGO:004480120.014
hemopoiesisGO:00300971830.014
melanin metabolic processGO:000658220.014
positive regulation of blood circulationGO:190352420.014
mucopolysaccharide metabolic processGO:190351020.014
glial cell migrationGO:000834730.014
regulation of protein polymerizationGO:003227120.014
response to organic substanceGO:00100331530.014
cell cycle g1 s phase transitionGO:004484310.014
negative regulation of epithelial cell proliferationGO:005068010.014
negative regulation of signal transductionGO:0009968940.014
oocyte maturationGO:000155640.014
cell matrix adhesionGO:000716040.014
optic placode formation involved in camera type eye formationGO:004661930.014
negative regulation of cytoplasmic transportGO:190365020.014
response to glucocorticoidGO:005138410.014
regulation of protein import into nucleusGO:004230620.014
regulation of cell deathGO:00109411030.014
b cell differentiationGO:003018310.014
negative regulation of catabolic processGO:000989530.014
regulation of cellular component organizationGO:0051128860.014
regulation of protein targetingGO:190353320.014
protein modification processGO:00362111000.014
cilium assemblyGO:0042384580.014
positive regulation of macromolecule biosynthetic processGO:0010557590.014
protein acylationGO:004354330.014
adherens junction organizationGO:003433240.014
positive regulation of notch signaling pathwayGO:004574730.013
extracellular matrix assemblyGO:008502910.013
cytokinesisGO:000091030.013
positive regulation of cytokine productionGO:000181920.013
phosphorus metabolic processGO:00067931090.013
cell substrate adhesionGO:003158940.013
apoptotic processGO:00069151160.013
positive regulation of cellular catabolic processGO:003133130.013
somatic muscle developmentGO:000752540.013
pancreas developmentGO:0031016840.013
striated muscle cell differentiationGO:00511461290.013
regulation of cellular carbohydrate metabolic processGO:001067540.013
cortical actin cytoskeleton organizationGO:003086610.013
macromolecular complex subunit organizationGO:0043933740.013
peptide transportGO:001583310.013
mesenchyme developmentGO:00604851270.013
phagocytosisGO:000690930.013
neurotransmitter transportGO:000683620.013
regulation of canonical wnt signaling pathwayGO:0060828340.013
negative regulation of protein kinase activityGO:000646940.013
phenol containing compound biosynthetic processGO:004618940.013
periodic partitioningGO:000736510.013
regulation of nucleoside metabolic processGO:000911820.013
multi organism processGO:00517041340.013
positive regulation of gene expressionGO:0010628710.013
organelle assemblyGO:00709251100.013
endocardial cushion formationGO:000327220.013
deathGO:00162651210.013
regulation of chondrocyte differentiationGO:003233010.013
response to hexoseGO:000974630.013
protein homooligomerizationGO:005126030.013
internal protein amino acid acetylationGO:000647520.013
actin filament based movementGO:003004810.013
fertilizationGO:000956630.013
lamellipodium assemblyGO:003003210.013
positive regulation of immune effector processGO:000269930.013
astrocyte differentiationGO:004870810.013
convergent extensionGO:00600261180.013
proximal distal pattern formationGO:000995410.013
regulation of jak stat cascadeGO:004642530.012
post embryonic organ developmentGO:004856940.012
positive regulation of nucleobase containing compound metabolic processGO:0045935690.012
axonogenesisGO:00074091520.012
regulation of metal ion transportGO:001095940.012
medulla oblongata developmentGO:002155040.012
single organism localizationGO:19025782250.012
regulation of nucleocytoplasmic transportGO:004682220.012
positive regulation of metabolic processGO:00098931080.012
endothelial cell fate commitmentGO:006083930.012
regulation of wound healingGO:006104120.012
ribonucleoside monophosphate catabolic processGO:000915840.012
hindbrain developmentGO:0030902910.012
internal peptidyl lysine acetylationGO:001839320.012
negative regulation of dna metabolic processGO:005105340.012
segment polarity determinationGO:000736710.012
rhombomere 6 developmentGO:002157240.012
protein acetylationGO:000647320.012
positive regulation of jak stat cascadeGO:004642720.012
phosphate containing compound metabolic processGO:00067961080.012
positive regulation of rna metabolic processGO:0051254590.012
negative regulation of chemotaxisGO:005092240.012
establishment of protein localization to plasma membraneGO:009000210.012
exocrine system developmentGO:0035272280.012
embryonic skeletal system developmentGO:0048706970.012
peptidyl lysine acetylationGO:001839420.012
regulation of synapse organizationGO:005080730.012
hormone secretionGO:004687920.012
positive regulation of apoptotic signaling pathwayGO:200123510.012
regulation of cell differentiationGO:00455951420.012
lateral line system developmentGO:0048925760.012
positive regulation of cell divisionGO:005178120.012
positive regulation of catabolic processGO:000989640.012
positive regulation of i kappab kinase nf kappab signalingGO:004312330.012
outflow tract morphogenesisGO:000315110.012
production of molecular mediator of immune responseGO:000244020.012
ketone biosynthetic processGO:004218120.012
cellular protein catabolic processGO:004425740.012
immune system developmentGO:00025201910.012
cognitionGO:005089010.011
regulation of catalytic activityGO:0050790550.011
cellular component assemblyGO:00226071700.011
negative regulation of secretionGO:005104820.011
motor neuron axon guidanceGO:0008045230.011
glucose homeostasisGO:004259310.011
cellular macromolecule biosynthetic processGO:00346452240.011
negative regulation of kinase activityGO:003367340.011
proteolysis involved in cellular protein catabolic processGO:005160330.011
cell proliferationGO:0008283800.011
regulation of production of molecular mediator of immune responseGO:000270010.011
regulation of blood pressureGO:000821710.011
embryonic limb morphogenesisGO:003032620.011
neuron projection guidanceGO:0097485860.011
cytoskeleton organizationGO:0007010960.011
regulation of response to extracellular stimulusGO:003210410.011
hard palate developmentGO:006002240.011
digestive tract developmentGO:00485652650.011
sensory organ morphogenesisGO:00905962000.011
negative regulation of intracellular protein transportGO:009031730.011
regulation of myotube differentiationGO:001083020.011
regulation of i kappab kinase nf kappab signalingGO:004312240.011
sequestering of metal ionGO:005123830.011
positive regulation of protein kinase b signalingGO:005189710.011
membrane fusionGO:006102520.011
regulation of programmed cell deathGO:00430671010.011
ubiquitin dependent protein catabolic processGO:000651130.011
odontogenesis of dentin containing toothGO:004247510.011
positive regulation of muscle cell differentiationGO:005114910.011
organism emergence from protective structureGO:007168440.011
positive regulation of nucleic acid templated transcriptionGO:1903508570.011
apoptotic process involved in morphogenesisGO:006056120.011
reactive nitrogen species metabolic processGO:200105700.011
protein heterooligomerizationGO:005129110.011
regulation of cell substrate adhesionGO:001081010.011
purine ribonucleoside monophosphate catabolic processGO:000916940.011
forebrain regionalizationGO:002187140.010
b cell activationGO:004211320.010
mitochondrion organizationGO:000700540.010
maternal determination of anterior posterior axis embryoGO:000835840.010
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.010
positive regulation of response to stimulusGO:0048584800.010
response to alkaloidGO:004327920.010
cell deathGO:00082191210.010
camera type eye morphogenesisGO:00485931080.010
regulation of cytokine biosynthetic processGO:004203510.010
dorsal convergenceGO:0060030140.010
convergent extension involved in gastrulationGO:0060027710.010
tissue regenerationGO:0042246740.010
cellular component maintenanceGO:004395430.010
regulation of purine nucleotide catabolic processGO:003312120.010
regulation of nucleotide catabolic processGO:003081120.010
actin filament polymerizationGO:003004120.010
digestive tract morphogenesisGO:00485462310.010
positive regulation of protein polymerizationGO:003227320.010
tissue remodelingGO:004877140.010
hatchingGO:003518840.010
skeletal system developmentGO:00015011810.010
response to external biotic stimulusGO:0043207970.010

ptk2.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.023
disease of metabolismDOID:001466700.022
inherited metabolic disorderDOID:65500.022
nervous system diseaseDOID:86300.012
cardiovascular system diseaseDOID:128700.011
musculoskeletal system diseaseDOID:1700.010