Danio rerio

0 known processes

top3a

topoisomerase (DNA) III alpha

top3a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sensory organ developmentGO:00074233930.131
immune system processGO:00023762410.109
nitrogen compound metabolic processGO:00068073190.109
Worm
immune system developmentGO:00025201910.103
cellular aromatic compound metabolic processGO:00067252950.094
Worm
digestive system developmentGO:00551232890.093
agingGO:000756820.090
cellular nitrogen compound metabolic processGO:00346412900.088
Worm
hematopoietic or lymphoid organ developmentGO:00485341910.083
heterocycle metabolic processGO:00464832900.061
Worm
larval developmentGO:000216420.060
digestive tract developmentGO:00485652650.059
nucleobase containing compound metabolic processGO:00061392740.059
Worm
eye developmentGO:00016542770.057
establishment of localizationGO:00512342440.052
cellular macromolecule metabolic processGO:00442603910.049
Worm
rna metabolic processGO:00160702190.047
cell morphogenesisGO:00009022890.047
nucleic acid metabolic processGO:00903042440.046
Worm
hemopoiesisGO:00300971830.042
gene expressionGO:00104672520.042
cellular component biogenesisGO:00440851780.040
gland developmentGO:00487321430.040
organic cyclic compound metabolic processGO:19013603010.039
Worm
nucleic acid templated transcriptionGO:00976591810.037
positive regulation of transportGO:005105020.037
transportGO:00068102200.035
leukocyte proliferationGO:007066110.034
regulation of biological qualityGO:00650082630.034
thymus developmentGO:0048538100.032
system processGO:00030081850.030
cellular component morphogenesisGO:00329893360.030
neuron differentiationGO:00301823530.029
cell surface receptor signaling pathwayGO:00071663250.028
regulation of multicellular organismal processGO:00512392770.028
multicellular organism growthGO:003526440.028
establishment of protein localization to organelleGO:007259440.028
maintenance of locationGO:005123540.027
regulation of anatomical structure morphogenesisGO:00226031300.027
regulation of establishment of protein localizationGO:007020140.027
cognitionGO:005089010.027
single organism localizationGO:19025782250.026
regulation of multicellular organism growthGO:004001440.026
regulation of gtp catabolic processGO:003312420.026
nucleocytoplasmic transportGO:000691340.026
cellular nitrogen compound biosynthetic processGO:00442712180.026
response to chemicalGO:00422213200.025
positive regulation of catabolic processGO:000989640.025
cation transportGO:0006812810.025
cellular component movementGO:00069283350.025
nucleobase containing compound biosynthetic processGO:00346542050.024
regulation of protein transportGO:005122330.024
tube morphogenesisGO:00352393490.024
cell migrationGO:00164772370.024
gtp metabolic processGO:004603940.023
swim bladder developmentGO:0048794190.023
morphogenesis of an epitheliumGO:00020093330.022
generation of neuronsGO:00486993850.022
regulation of rna biosynthetic processGO:20011412130.022
digestive tract morphogenesisGO:00485462310.022
guanosine containing compound metabolic processGO:190106840.022
rna biosynthetic processGO:00327741810.022
protein localization to nucleusGO:003450430.021
regulation of calcium ion transportGO:005192420.021
protein targeting to nucleusGO:004474430.021
stem cell maintenanceGO:001982740.021
positive regulation of secretion by cellGO:190353210.021
rna processingGO:0006396250.021
protein import into nucleusGO:000660630.021
positive regulation of cellular catabolic processGO:003133130.020
single organism metabolic processGO:00447102170.020
regulation of cytoplasmic transportGO:190364940.020
cell morphogenesis involved in differentiationGO:00009041950.020
regulation of nucleobase containing compound metabolic processGO:00192192500.020
regulation of developmental processGO:00507932470.020
locomotionGO:00400113130.020
regulation of metal ion transportGO:001095940.020
regionalizationGO:00030022740.020
single organism nuclear importGO:190259330.020
homeostatic processGO:00425921420.019
localization of cellGO:00516742440.019
heart developmentGO:00075073130.019
cell projection organizationGO:00300302840.019
cell projection morphogenesisGO:00488582440.019
cellular response to chemical stimulusGO:00708871570.019
positive regulation of secretionGO:005104710.019
regulation of purine nucleotide catabolic processGO:003312120.019
central nervous system developmentGO:00074173870.019
protein metabolic processGO:00195381830.019
cellular macromolecule biosynthetic processGO:00346452240.018
meiotic nuclear divisionGO:000712640.018
Worm
regulation of multicellular organismal developmentGO:20000262230.018
nuclear importGO:005117030.018
multicellular organismal signalingGO:0035637220.018
nuclear transportGO:005116940.018
regulation of metabolic processGO:00192223590.018
single organism transportGO:00447652060.018
brain developmentGO:00074202930.018
organonitrogen compound metabolic processGO:1901564740.018
regulation of cellular macromolecule biosynthetic processGO:20001122220.018
gtp catabolic processGO:000618420.018
transcription dna templatedGO:00063511810.018
organelle organizationGO:00069962270.018
Worm
regulation of response to stimulusGO:00485832690.017
regulation of macromolecule metabolic processGO:00602553170.017
stem cell proliferationGO:007208940.017
regulation of nucleoside metabolic processGO:000911820.017
regulation of cellular biosynthetic processGO:00313262450.017
positive regulation of nucleoside metabolic processGO:004597910.017
transmission of nerve impulseGO:0019226190.017
peptide transportGO:001583310.017
regulation of cytokine productionGO:000181730.017
regulation of transcription dna templatedGO:00063552130.017
regulation of intracellular protein transportGO:003315730.017
cell part morphogenesisGO:00329902460.017
regulation of gtpase activityGO:004308720.016
response to external stimulusGO:00096052640.016
neuron projection morphogenesisGO:00488121610.016
liver developmentGO:0001889960.016
protein importGO:001703830.016
signal transductionGO:00071654550.016
cellular component disassemblyGO:002241110.016
regulation of cell activationGO:005086510.015
leukocyte homeostasisGO:000177620.015
regulation of nucleotide catabolic processGO:003081120.015
regulation of epithelial cell proliferationGO:005067830.015
regulation of jak stat cascadeGO:004642530.015
small molecule metabolic processGO:0044281770.015
regulation of rna metabolic processGO:00512522240.015
proteasomal protein catabolic processGO:001049820.015
cellular amine metabolic processGO:004410620.015
regulation of nucleocytoplasmic transportGO:004682220.015
cellular amino acid metabolic processGO:000652070.015
meiotic cell cycle processGO:190304630.015
cytokinesisGO:000091030.015
exocytosisGO:000688710.015
guanosine containing compound catabolic processGO:190106920.014
action potentialGO:0001508190.014
cytosolic calcium ion transportGO:006040130.014
neuronal action potentialGO:0019228180.014
cell cycle g1 s phase transitionGO:004484310.014
regulation of cellular ketone metabolic processGO:001056570.014
regulation of signalingGO:00230512350.014
regulation of protein catabolic processGO:004217610.014
amine metabolic processGO:000930820.014
regulation of cell shapeGO:000836010.014
production of molecular mediator of immune responseGO:000244020.014
regulation of cellular protein catabolic processGO:190336210.014
regulation of cellular amine metabolic processGO:003323800.014
lymphocyte proliferationGO:004665110.014
vasculature developmentGO:00019442780.013
regulation of cellular metabolic processGO:00313233200.013
blood vessel morphogenesisGO:00485142160.013
modification dependent macromolecule catabolic processGO:004363230.013
heterocycle biosynthetic processGO:00181302150.013
response to ketoneGO:190165410.013
negative regulation of biological processGO:00485193040.013
erk1 and erk2 cascadeGO:007037140.013
hormone transportGO:000991420.013
neurological system processGO:0050877620.013
modification dependent protein catabolic processGO:001994130.013
growthGO:00400071740.013
positive regulation of purine nucleotide catabolic processGO:003312310.013
cellular biosynthetic processGO:00442492860.013
positive regulation of gtpase activityGO:004354710.013
sequestering of metal ionGO:005123830.013
neuron projection developmentGO:00311751800.013
response to other organismGO:0051707970.013
macromolecule biosynthetic processGO:00090592270.013
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.013
mononuclear cell proliferationGO:003294310.012
positive regulation of gtp catabolic processGO:003312610.012
regulation of biosynthetic processGO:00098892500.012
regulation of protein localization to nucleusGO:190018020.012
developmental growthGO:00485891660.012
response to organic substanceGO:00100331530.012
regulation of nucleic acid templated transcriptionGO:19035062130.012
negative regulation of cellular processGO:00485232830.012
extrinsic apoptotic signaling pathwayGO:009719130.012
g1 s transition of mitotic cell cycleGO:000008210.012
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.012
ameboidal type cell migrationGO:00016671430.012
response to woundingGO:00096111160.012
sensory organ morphogenesisGO:00905962000.012
cellular response to organic substanceGO:00713101050.012
hepaticobiliary system developmentGO:0061008980.012
positive regulation of epithelial cell proliferationGO:005067910.012
macromolecular complex disassemblyGO:003298410.012
ion transportGO:00068111140.012
gastrulationGO:00073692080.012
carboxylic acid metabolic processGO:0019752220.012
regulation of gene expressionGO:00104682650.012
cellular protein catabolic processGO:004425740.012
biosynthetic processGO:00090582940.012
negative regulation of protein transportGO:005122430.012
proteolysis involved in cellular protein catabolic processGO:005160330.012
regulation of cell communicationGO:00106462320.012
blood vessel developmentGO:00015682460.012
oxoacid metabolic processGO:0043436310.012
positive regulation of stress activated mapk cascadeGO:003287430.012
negative regulation of catabolic processGO:000989530.012
rna localizationGO:000640340.011
regulation of reproductive processGO:200024140.011
urogenital system developmentGO:0001655970.011
aromatic compound biosynthetic processGO:00194382170.011
pancreas developmentGO:0031016840.011
regulation of production of molecular mediator of immune responseGO:000270010.011
response to external biotic stimulusGO:0043207970.011
regulation of erk1 and erk2 cascadeGO:007037240.011
response to drugGO:004249330.011
regulation of cellular amino acid metabolic processGO:000652100.011
autophagyGO:000691440.011
regulation of protein targetingGO:190353320.011
organic substance biosynthetic processGO:19015762890.011
positive regulation of cell cycleGO:004578730.011
skeletal system developmentGO:00015011810.011
positive regulation of nucleotide catabolic processGO:003081310.011
actin mediated cell contractionGO:007025210.011
regulation of membrane potentialGO:0042391230.011
neuron developmentGO:00486662620.011
regulation of protein import into nucleusGO:004230620.011
glucose homeostasisGO:004259310.011
regulation of nitrogen compound metabolic processGO:00511712510.011
i kappab kinase nf kappab signalingGO:000724940.011
compound eye developmentGO:004874920.011
regulation of primary metabolic processGO:00800903110.011
regulation of ras gtpase activityGO:003231820.011
regulation of muscle contractionGO:000693730.011
enzyme linked receptor protein signaling pathwayGO:00071671060.011
ubiquitin dependent protein catabolic processGO:000651130.011
negative regulation of immune responseGO:005077720.011
transcription from rna polymerase ii promoterGO:0006366800.011
cell motilityGO:00488702440.011
cell morphogenesis involved in neuron differentiationGO:00486671630.011
signal transduction in absence of ligandGO:003803410.011
regulation of macromolecule biosynthetic processGO:00105562250.011
negative regulation of nitrogen compound metabolic processGO:0051172590.011
tissue regenerationGO:0042246740.011
positive regulation of response to stimulusGO:0048584800.011
muscle structure developmentGO:00610611960.011
wound healingGO:0042060900.011
regulation of localizationGO:00328791040.010
vesicle mediated transportGO:0016192220.010
macromolecule modificationGO:00434121110.010
cell proliferationGO:0008283800.010
hormone secretionGO:004687920.010
embryonic organ morphogenesisGO:00485622740.010
cytoskeleton organizationGO:0007010960.010
negative regulation of cellular metabolic processGO:0031324770.010
protein complex disassemblyGO:004324110.010
negative regulation of cellular catabolic processGO:003133030.010
response to stressGO:00069502630.010
double strand break repairGO:000630230.010
regulation of bindingGO:005109830.010

top3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.039
nervous system diseaseDOID:86300.015
musculoskeletal system diseaseDOID:1700.012