Danio rerio

77 known processes

esr2a

estrogen receptor 2a

(Aliases: ER[b]2,ER[b]a,zfER-beta2,zfER[b]2)

esr2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
steroid hormone mediated signaling pathwayGO:004340191.000
hormone mediated signaling pathwayGO:000975590.997
heterocycle biosynthetic processGO:00181302150.864
organic cyclic compound biosynthetic processGO:19013622230.857
camera type eye developmentGO:00430102220.804
negative regulation of cellular processGO:00485232830.795
Human Mouse Rat
regulation of macromolecule biosynthetic processGO:00105562250.772
locomotionGO:00400113130.732
Zebrafish Mouse
cellular response to hormone stimulusGO:0032870390.708
cell surface receptor signaling pathwayGO:00071663250.703
Rat
cellular response to estrogen stimulusGO:0071391240.653
Zebrafish Rat
multicellular organism growthGO:003526440.625
regulation of cell communicationGO:00106462320.625
Mouse Rat
intracellular receptor signaling pathwayGO:0030522300.618
otolith formationGO:003247520.612
Zebrafish
response to dexamethasoneGO:007154810.581
Rat
regulation of signal transductionGO:00099662250.556
Mouse Rat
nucleobase containing compound biosynthetic processGO:00346542050.548
response to organic substanceGO:00100331530.546
signal transductionGO:00071654550.519
organic substance biosynthetic processGO:19015762890.513
biosynthetic processGO:00090582940.510
cellular macromolecule metabolic processGO:00442603910.497
regulation of cellular macromolecule biosynthetic processGO:20001122220.494
regulation of cellular metabolic processGO:00313233200.483
intracellular estrogen receptor signaling pathwayGO:003052030.471
aromatic compound biosynthetic processGO:00194382170.470
cellular response to chemical stimulusGO:00708871570.453
regulation of biosynthetic processGO:00098892500.448
rna metabolic processGO:00160702190.437
regulation of nucleic acid templated transcriptionGO:19035062130.429
negative regulation of nucleobase containing compound metabolic processGO:0045934590.423
Human Rat
cellular response to steroid hormone stimulusGO:0071383310.421
negative regulation of nitrogen compound metabolic processGO:0051172590.392
Human Rat
regulation of gene expressionGO:00104682650.389
carbohydrate metabolic processGO:0005975120.376
Fly
nucleic acid templated transcriptionGO:00976591810.376
enzyme linked receptor protein signaling pathwayGO:00071671060.373
Rat
g protein coupled receptor signaling pathwayGO:0007186740.371
regulation of developmental processGO:00507932470.362
sensory organ developmentGO:00074233930.358
Zebrafish
regulation of signalingGO:00230512350.355
Mouse Rat
regulation of multicellular organismal processGO:00512392770.338
determination of left right symmetryGO:00073681790.337
purine nucleotide biosynthetic processGO:0006164200.324
gland developmentGO:00487321430.321
Mouse Rat
positive regulation of gene expressionGO:0010628710.320
Rat
cell cell signalingGO:0007267520.318
regulation of primary metabolic processGO:00800903110.313
growthGO:00400071740.311
transcription from rna polymerase ii promoterGO:0006366800.306
determination of heart left right asymmetryGO:00613711170.303
negative regulation of biological processGO:00485193040.292
Human Mouse Rat
homeostatic processGO:00425921420.281
programmed cell deathGO:00125011190.277
Mouse Rat
chemical homeostasisGO:0048878490.276
regulation of macromolecule metabolic processGO:00602553170.274
response to stressGO:00069502630.274
Rat
embryonic organ developmentGO:00485683810.249
Zebrafish
regulation of cell deathGO:00109411030.243
Rat
heart developmentGO:00075073130.239
regulation of rna metabolic processGO:00512522240.233
organic cyclic compound metabolic processGO:19013603010.232
cellular biosynthetic processGO:00442492860.230
apoptotic processGO:00069151160.228
Mouse Rat
maintenance of locationGO:005123540.228
glucose homeostasisGO:004259310.224
positive regulation of cellular biosynthetic processGO:0031328680.222
Rat
positive regulation of signal transductionGO:0009967560.216
Rat
regulation of transcription dna templatedGO:00063552130.210
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.208
Rat
positive regulation of rna metabolic processGO:0051254590.205
Rat
cellular macromolecule biosynthetic processGO:00346452240.201
establishment of localization in cellGO:0051649770.201
sensory organ morphogenesisGO:00905962000.195
Zebrafish
gastrulationGO:00073692080.190
Zebrafish
regulation of multicellular organism growthGO:004001440.187
macromolecule biosynthetic processGO:00090592270.186
negative regulation of biosynthetic processGO:0009890550.182
Human Rat
cellular nitrogen compound biosynthetic processGO:00442712180.180
regulation of cardiac muscle tissue developmentGO:005502410.178
positive regulation of response to stimulusGO:0048584800.176
Rat
negative regulation of nucleic acid templated transcriptionGO:1903507450.172
Human Rat
response to hormoneGO:0009725480.171
embryonic organ morphogenesisGO:00485622740.169
Zebrafish
rna biosynthetic processGO:00327741810.165
lipid metabolic processGO:0006629520.164
negative regulation of cellular biosynthetic processGO:0031327550.162
Human Rat
regulation of nucleobase containing compound metabolic processGO:00192192500.150
eye morphogenesisGO:00485921440.149
protein metabolic processGO:00195381830.147
regulation of phosphorus metabolic processGO:0051174430.147
Rat
regulation of nervous system developmentGO:0051960900.146
negative regulation of innate immune responseGO:004582420.145
specification of symmetryGO:00097992040.145
response to lipidGO:0033993600.141
gene expressionGO:00104672520.138
regulation of cellular biosynthetic processGO:00313262450.138
response to oxygen containing compoundGO:1901700550.136
Zebrafish Rat
developmental growthGO:00485891660.133
positive regulation of metabolic processGO:00098931080.130
Rat
cellular component movementGO:00069283350.125
Zebrafish Mouse
nitrogen compound metabolic processGO:00068073190.122
regulation of response to oxidative stressGO:190288220.119
light adaptionGO:003636710.118
response to alkaloidGO:004327920.116
negative regulation of macromolecule biosynthetic processGO:0010558480.116
Human Rat
positive regulation of transcription dna templatedGO:0045893570.112
Rat
regulation of rna biosynthetic processGO:20011412130.111
hormone secretionGO:004687920.110
transcription dna templatedGO:00063511810.110
response to chemicalGO:00422213200.108
cation homeostasisGO:0055080330.107
ovulation cycleGO:004269820.105
Mouse Rat
cell projection morphogenesisGO:00488582440.102
single organism transportGO:00447652060.101
cellular response to estradiol stimulusGO:007139210.101
Rat
rhythmic processGO:0048511210.100
Mouse Rat
response to external stimulusGO:00096052640.099
Rat
positive regulation of nucleic acid templated transcriptionGO:1903508570.098
Rat
establishment of localizationGO:00512342440.097
striated muscle cell differentiationGO:00511461290.095
hormone transportGO:000991420.094
negative regulation of signal transductionGO:0009968940.094
Mouse
regulation of cellular protein metabolic processGO:0032268520.094
tube morphogenesisGO:00352393490.092
Zebrafish
positive regulation of nitrogen compound metabolic processGO:0051173690.091
Rat
dicarboxylic acid transportGO:000683510.090
negative regulation of feeding behaviorGO:200025220.089
Rat
positive regulation of macromolecule biosynthetic processGO:0010557590.088
Rat
negative regulation of response to stimulusGO:00485851040.087
Mouse Rat
positive regulation of rna biosynthetic processGO:1902680570.085
Rat
cellular localizationGO:0051641970.084
single organism localizationGO:19025782250.083
regulation of multicellular organismal developmentGO:20000262230.080
positive regulation of signalingGO:0023056560.079
Rat
larval developmentGO:000216420.078
cell motilityGO:00488702440.077
Zebrafish Mouse
organelle organizationGO:00069962270.077
negative regulation of cell communicationGO:0010648960.075
Mouse
carbohydrate homeostasisGO:003350010.075
posterior lateral line neuromast primordium migrationGO:0048920120.075
Zebrafish
macromolecule localizationGO:0033036540.074
digestive tract morphogenesisGO:00485462310.074
Zebrafish
hepaticobiliary system developmentGO:0061008980.073
cellular protein metabolic processGO:00442671290.072
regulation of apoptotic processGO:0042981980.072
Rat
negative regulation of macromolecule metabolic processGO:0010605760.071
Human Rat
camera type eye morphogenesisGO:00485931080.070
localization of cellGO:00516742440.070
Zebrafish Mouse
phosphate containing compound metabolic processGO:00067961080.069
Rat
cellular response to organic substanceGO:00713101050.069
macromolecule modificationGO:00434121110.068
negative regulation of cellular metabolic processGO:0031324770.067
Human Rat
odontogenesis of dentin containing toothGO:004247510.066
regulation of response to stimulusGO:00485832690.066
Mouse Rat
negative regulation of gene expressionGO:0010629650.066
Human Rat
ion homeostasisGO:0050801410.066
regulation of heart growthGO:006042020.065
deathGO:00162651210.065
Mouse Rat
stem cell divisionGO:001714510.064
single organism metabolic processGO:00447102170.063
Rat
positive regulation of phosphate metabolic processGO:0045937210.063
Rat
embryonic heart tube morphogenesisGO:00031431080.063
positive regulation of macromolecule metabolic processGO:0010604930.063
Rat
liver developmentGO:0001889960.059
regionalizationGO:00030022740.058
response to endogenous stimulusGO:0009719830.058
determination of bilateral symmetryGO:00098552040.057
intracellular signal transductionGO:0035556850.057
Rat
single organism biosynthetic processGO:0044711710.056
organic acid transportGO:001584990.055
regulation of nitrogen compound metabolic processGO:00511712510.055
regulation of cellular carbohydrate metabolic processGO:001067540.054
carboxylic acid transportGO:004694280.053
regulation of localizationGO:00328791040.053
regulation of intracellular signal transductionGO:1902531570.052
Rat
camp metabolic processGO:0046058110.051
cellular lipid metabolic processGO:0044255360.049
transportGO:00068102200.049
regulation of protein metabolic processGO:0051246560.049
positive regulation of cell communicationGO:0010647560.048
Rat
system processGO:00030081850.048
Rat
negative regulation of apoptotic processGO:0043066550.047
regulation of blood vessel sizeGO:005088020.045
regulation of phosphate metabolic processGO:0019220430.045
Rat
regulation of cellular component organizationGO:0051128860.045
positive regulation of cellular metabolic processGO:0031325940.045
Rat
response to fibroblast growth factorGO:0071774220.045
nitrogen compound transportGO:0071705230.045
reflexGO:006000420.044
negative regulation of cell deathGO:0060548600.044
Rat
behaviorGO:0007610740.043
Rat
triglyceride homeostasisGO:007032820.043
anion transportGO:0006820380.042
regulation of cell developmentGO:00602841000.041
agingGO:000756820.041
response to estradiolGO:003235560.040
Zebrafish Rat
mesenchyme developmentGO:00604851270.040
kupffer s vesicle developmentGO:0070121500.039
organ growthGO:0035265120.039
lateral line system developmentGO:0048925760.038
Zebrafish
fin developmentGO:0033333770.038
mitochondrion organizationGO:000700540.037
cognitionGO:005089010.037
Rat
pancreas developmentGO:0031016840.037
lateral line developmentGO:0048882660.037
Zebrafish
cell deathGO:00082191210.037
Mouse Rat
cellular response to oxygen containing compoundGO:1901701200.036
Rat
response to cortisolGO:005141410.036
regulation of carbohydrate metabolic processGO:000610940.036
response to woundingGO:00096111160.036
heterocycle metabolic processGO:00464832900.035
cell projection organizationGO:00300302840.035
cellular response to nitrogen compoundGO:190169960.035
primary amino compound biosynthetic processGO:190116210.035
response to organic cyclic compoundGO:0014070510.034
regulation of biological qualityGO:00650082630.034
regulation of growthGO:0040008420.034
divalent inorganic cation homeostasisGO:0072507220.034
regulation of organ growthGO:004662030.034
neuromast primordium migrationGO:0048883120.034
Zebrafish
androgen metabolic processGO:000820920.033
small molecule metabolic processGO:0044281770.033
organic hydroxy compound biosynthetic processGO:190161760.033
posterior lateral line developmentGO:0048916380.033
Zebrafish
female gonad developmentGO:000858540.033
Mouse Rat
hard palate developmentGO:006002240.033
catechol containing compound biosynthetic processGO:000971320.032
negative regulation of rna metabolic processGO:0051253480.032
Human Rat
positive regulation of biological processGO:00485182530.032
Human Rat
regulation of reactive oxygen species metabolic processGO:200037720.032
Rat
nucleic acid metabolic processGO:00903042440.031
gamma aminobutyric acid signaling pathwayGO:000721410.031
cellular response to lipidGO:0071396390.031
reproductive processGO:0022414400.031
Mouse Rat
negative regulation of rna biosynthetic processGO:1902679450.031
Human Rat
retina development in camera type eyeGO:00600411460.030
regulation of hormone secretionGO:004688320.030
meiotic nuclear divisionGO:000712640.030
organic substance transportGO:0071702580.030
skin developmentGO:0043588540.029
regulation of neural retina developmentGO:006107420.029
positive regulation of developmental processGO:0051094500.029
mechanosensory lateral line system developmentGO:0048881490.029
Zebrafish
lipid storageGO:001991510.028
organic anion transportGO:0015711150.027
neuron differentiationGO:00301823530.027
regulation of molecular functionGO:0065009700.027
Human
regulation of developmental growthGO:0048638380.027
regulation of programmed cell deathGO:00430671010.027
Rat
digestive system developmentGO:00551232890.027
Zebrafish
determination of dorsal ventral asymmetryGO:0048262340.027
regulation of transcription from rna polymerase ii promoterGO:00063571140.027
ovarian follicle developmentGO:000154120.026
Mouse Rat
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.026
bmp signaling pathwayGO:0030509520.026
negative regulation of programmed cell deathGO:0043069580.026
negative regulation of signalingGO:0023057960.025
Mouse
single organism organelle organizationGO:19025891990.024
positive regulation of nucleobase containing compound metabolic processGO:0045935690.024
Rat
muscle cell developmentGO:00550011150.024
negative regulation of catalytic activityGO:0043086210.024
response to xenobiotic stimulusGO:0009410450.024
Zebrafish
negative regulation of protein kinase activityGO:000646940.023
regulation of catalytic activityGO:0050790550.023
pigmentationGO:0043473850.023
wound healingGO:0042060900.023
somitogenesisGO:0001756870.022
cellular nitrogen compound metabolic processGO:00346412900.022
response to steroid hormoneGO:0048545350.022
neural retina developmentGO:0003407490.021
digestive tract developmentGO:00485652650.021
Zebrafish
organic acid metabolic processGO:0006082310.021
positive regulation of phosphorus metabolic processGO:0010562210.021
Rat
response to ketoneGO:190165410.021
Rat
negative regulation of metabolic processGO:0009892860.021
Human Rat
regulation of reproductive processGO:200024140.021
positive regulation of protein metabolic processGO:0051247230.021
negative regulation of response to cytokine stimulusGO:006076120.021
hormone metabolic processGO:0042445190.020
oligodendrocyte differentiationGO:0048709230.020
response to inorganic substanceGO:0010035380.020
Rat
cellular response to endogenous stimulusGO:0071495680.020
cell proliferationGO:0008283800.020
Mouse Rat
positive regulation of secretion by cellGO:190353210.019
phosphorylationGO:0016310690.019
Rat
cellular hormone metabolic processGO:0034754190.019
positive regulation of cellular catabolic processGO:003133130.019
neurological system processGO:0050877620.019
Rat
cell migrationGO:00164772370.019
Zebrafish Mouse
positive regulation of secretionGO:005104710.019
regulation of neurogenesisGO:0050767870.018
negative regulation of developmental processGO:0051093650.018
ear developmentGO:00435831270.018
Zebrafish
cellular response to peptide hormone stimulusGO:007137550.018
cellular response to organic cyclic compoundGO:0071407380.018
single organism carbohydrate metabolic processGO:0044723120.018
activation of mapk activityGO:000018730.018
regulation of lipid catabolic processGO:005099420.017
calcium ion homeostasisGO:0055074190.017
vesicle localizationGO:0051648270.017
terpenoid catabolic processGO:001611520.017
vitamin catabolic processGO:000911120.017
organonitrogen compound metabolic processGO:1901564740.017
axis elongationGO:0003401310.017
ovulation cycle processGO:002260220.016
Mouse Rat
regulation of cell proliferationGO:0042127370.016
Mouse Rat
response to acid chemicalGO:0001101170.016
Rat
neuron projection developmentGO:00311751800.016
cellular response to growth factor stimulusGO:0071363390.016
striated muscle cell developmentGO:00550021080.015
positive regulation of muscle organ developmentGO:004863610.015
cellular biogenic amine metabolic processGO:000657620.015
fin regenerationGO:0031101510.015
phosphorus metabolic processGO:00067931090.015
Rat
cellular aromatic compound metabolic processGO:00067252950.015
negative regulation of transcription dna templatedGO:0045892450.015
Human Rat
regulation of neurological system processGO:003164420.015
regulation of metabolic processGO:00192223590.015
metal ion homeostasisGO:0055065260.015
fatty acid oxidationGO:001939510.014
primary amino compound metabolic processGO:190116010.014
amino acid transportGO:000686520.014
positive regulation of transportGO:005105020.014
development of primary female sexual characteristicsGO:004654540.014
Mouse Rat
blood vessel morphogenesisGO:00485142160.014
regulation of protein complex assemblyGO:004325430.014
ear morphogenesisGO:0042471640.014
Zebrafish
hindbrain developmentGO:0030902910.014
Rat
positive regulation of cell cycleGO:004578730.014
response to abiotic stimulusGO:00096281220.014
Rat
defense responseGO:0006952470.014
Rat
neuron developmentGO:00486662620.014
neurotransmitter transportGO:000683620.013
regulation of cell cycleGO:0051726520.013
positive regulation of lipid metabolic processGO:004583410.013
cellular carbohydrate metabolic processGO:004426240.013
inner ear morphogenesisGO:0042472630.013
Zebrafish
circadian sleep wake cycle sleepGO:005080210.013
determination of pancreatic left right asymmetryGO:0035469110.013
posterior commissure morphogenesisGO:002196110.013
response to growth factorGO:0070848390.013
sensory perception of smellGO:000760820.013
regulation of cellular component movementGO:0051270550.013
cellular component biogenesisGO:00440851780.013
cell morphogenesisGO:00009022890.013
regulation of establishment of protein localizationGO:007020140.013
cellular response to fibroblast growth factor stimulusGO:0044344220.013
heart loopingGO:0001947940.013
circulatory system processGO:0003013870.013
multicellular organismal reproductive processGO:0048609350.013
Mouse Rat
intracellular steroid hormone receptor signaling pathwayGO:003051850.012
regulation of hormone levelsGO:0010817210.012
positive regulation of cellular processGO:00485222010.012
Rat
diterpenoid catabolic processGO:001610320.012
protein modification processGO:00362111000.012
urogenital system developmentGO:0001655970.012
Mouse Rat
axon extensionGO:0048675450.012
positive regulation of biosynthetic processGO:0009891680.012
Rat
embryonic heart tube developmentGO:00350501330.012
female sex differentiationGO:004666040.012
Mouse Rat
protein complex disassemblyGO:004324110.012
diencephalon developmentGO:0021536580.012
Rat
tissue regenerationGO:0042246740.012
cellular component assemblyGO:00226071700.012
cellular response to retinoic acidGO:007130010.012
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathwayGO:002200210.012
specification of organ identityGO:001009220.011
regulation of calcium ion transport into cytosolGO:001052210.011
germ line stem cell maintenanceGO:003071820.011
cellular response to vitamin aGO:007129910.011
regulation of phosphorylationGO:0042325260.011
Rat
regulation of alcohol biosynthetic processGO:190293010.011
multi organism processGO:00517041340.011
response to peptide hormoneGO:004343460.011
response to hexoseGO:000974630.011
lipid biosynthetic processGO:0008610220.011
aromatic amino acid family metabolic processGO:000907210.011
fat soluble vitamin catabolic processGO:004236320.011
peptide transportGO:001583310.011
positive regulation of molecular functionGO:0044093330.011
Human
regulation of protein complex disassemblyGO:004324410.011
stem cell maintenanceGO:001982740.011
cell migration involved in gastrulationGO:0042074790.011
Zebrafish
organelle localizationGO:0051640490.010
fibroblast growth factor receptor signaling pathwayGO:0008543220.010
muscle organ developmentGO:00075171010.010
response to monosaccharideGO:003428430.010
eye developmentGO:00016542770.010
response to peptideGO:190165260.010
positive regulation of neural precursor cell proliferationGO:200017910.010
positive regulation of multicellular organismal processGO:0051240520.010
regulation of protein phosphorylationGO:0001932180.010
long chain fatty acid transportGO:001590910.010
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.010
Human Rat

esr2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.109
musculoskeletal system diseaseDOID:1700.024
acrocephalosyndactyliaDOID:1296000.024
connective tissue diseaseDOID:6500.024
synostosisDOID:1197100.024
bone development diseaseDOID:008000600.024
bone diseaseDOID:008000100.024
dysostosisDOID:193400.024
osteochondrodysplasiaDOID:225600.023
cleidocranial dysplasiaDOID:1399400.023
pfeiffer syndromeDOID:1470500.020
heart diseaseDOID:11400.015
congenital heart diseaseDOID:168200.015
heart septal defectDOID:168100.015
cardiovascular system diseaseDOID:128700.015
atrioventricular septal defectDOID:005065100.015
disease of mental healthDOID:15000.014
developmental disorder of mental healthDOID:006003700.014
cancerDOID:16200.014
disease of cellular proliferationDOID:1456600.014
tooth and nail syndromeDOID:667800.013
syndromeDOID:22500.013
organ system cancerDOID:005068600.013
kidney cancerDOID:26300.013
urinary system cancerDOID:399600.013
nephroblastomaDOID:215400.013
visual pathway diseaseDOID:139300.012
nervous system diseaseDOID:86300.012
eye diseaseDOID:561400.012
eye and adnexa diseaseDOID:149200.012
sensory system diseaseDOID:005015500.012
iris diseaseDOID:24000.010
aniridiaDOID:1227100.010
uveal diseaseDOID:348000.010