Danio rerio

52 known processes

heatr1

HEAT repeat containing 1

(Aliases: fi69e12,wu:fi69e12,zgc:63510,BAP28,BAP28-like,flj10359,zC146F4.2)

heatr1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.467
Worm
cellular macromolecule metabolic processGO:00442603910.219
generation of neuronsGO:00486993850.198
nitrogen compound metabolic processGO:00068073190.195
regulation of meiotic cell cycleGO:005144510.150
nuclear transportGO:005116940.136
meiotic nuclear divisionGO:000712640.128
cellular aromatic compound metabolic processGO:00067252950.128
locomotionGO:00400113130.113
Worm
morphogenesis of an epitheliumGO:00020093330.108
immune system developmentGO:00025201910.104
cellular component biogenesisGO:00440851780.104
regulation of cellular ketone metabolic processGO:001056570.090
nucleobase containing compound metabolic processGO:00061392740.087
nucleobase containing compound biosynthetic processGO:00346542050.086
organic cyclic compound metabolic processGO:19013603010.083
negative regulation of cellular processGO:00485232830.081
localization of cellGO:00516742440.078
meiotic cell cycle processGO:190304630.074
macromolecule biosynthetic processGO:00090592270.074
cell morphogenesisGO:00009022890.073
heterocycle metabolic processGO:00464832900.072
establishment of localizationGO:00512342440.071
organelle assemblyGO:00709251100.071
cell projection morphogenesisGO:00488582440.068
gene expressionGO:00104672520.067
microtubule based processGO:0007017600.064
deathGO:00162651210.064
response to chemicalGO:00422213200.063
agingGO:000756820.062
rna metabolic processGO:00160702190.062
rna localizationGO:000640340.061
regulation of nucleic acid templated transcriptionGO:19035062130.058
cellular macromolecule biosynthetic processGO:00346452240.057
cellular component movementGO:00069283350.057
nucleocytoplasmic transportGO:000691340.055
heart developmentGO:00075073130.055
meiotic chromosome segregationGO:004513230.054
single organism localizationGO:19025782250.054
carboxylic acid metabolic processGO:0019752220.053
negative regulation of biological processGO:00485193040.052
single organism metabolic processGO:00447102170.052
mitotic dna integrity checkpointGO:004477440.051
regulation of biological qualityGO:00650082630.051
cellular protein metabolic processGO:00442671290.051
organic substance biosynthetic processGO:19015762890.051
regionalizationGO:00030022740.048
system processGO:00030081850.048
cellular nitrogen compound biosynthetic processGO:00442712180.048
heart morphogenesisGO:00030071560.048
regulation of nervous system developmentGO:0051960900.048
cell morphogenesis involved in neuron differentiationGO:00486671630.048
spindle assembly involved in mitosisGO:009030710.047
amine metabolic processGO:000930820.047
aromatic compound biosynthetic processGO:00194382170.046
cellular component morphogenesisGO:00329893360.046
nucleic acid metabolic processGO:00903042440.046
regulation of cellular amino acid metabolic processGO:000652100.045
organelle organizationGO:00069962270.045
growthGO:00400071740.045
brain developmentGO:00074202930.044
regulation of neurogenesisGO:0050767870.044
response to external stimulusGO:00096052640.044
positive regulation of biological processGO:00485182530.044
sensory system developmentGO:0048880760.044
embryo development ending in birth or egg hatchingGO:00097922710.044
Worm
regulation of cellular amine metabolic processGO:003323800.043
heart loopingGO:0001947940.043
stem cell proliferationGO:007208940.043
multicellular organism growthGO:003526440.043
cellular amine metabolic processGO:004410620.043
g1 s transition of mitotic cell cycleGO:000008210.043
regulation of peptidyl tyrosine phosphorylationGO:005073010.043
cellular response to external stimulusGO:007149620.042
cell part morphogenesisGO:00329902460.042
spindle assemblyGO:005122520.042
cell motilityGO:00488702440.041
mitotic cell cycleGO:0000278640.041
protein importGO:001703830.040
blood vessel morphogenesisGO:00485142160.040
tube morphogenesisGO:00352393490.040
regulation of neuron differentiationGO:0045664560.040
developmental growthGO:00485891660.040
cell migrationGO:00164772370.040
cytoskeleton organizationGO:0007010960.039
regulation of cellular biosynthetic processGO:00313262450.039
embryonic organ developmentGO:00485683810.039
neuron differentiationGO:00301823530.038
neuron developmentGO:00486662620.038
cellular component disassemblyGO:002241110.038
guanosine containing compound metabolic processGO:190106840.038
cell surface receptor signaling pathwayGO:00071663250.038
mitotic g2 m transition checkpointGO:004481830.037
blood vessel developmentGO:00015682460.036
determination of heart left right asymmetryGO:00613711170.036
hematopoietic or lymphoid organ developmentGO:00485341910.035
regulation of developmental processGO:00507932470.035
cellular biosynthetic processGO:00442492860.035
microtubule organizing center organizationGO:003102310.035
centrosome organizationGO:005129710.035
phosphorus metabolic processGO:00067931090.035
hemopoiesisGO:00300971830.035
response to stressGO:00069502630.034
regulation of stem cell proliferationGO:007209120.034
phagocytosisGO:000690930.034
single organism nuclear importGO:190259330.033
single organism organelle organizationGO:19025891990.033
cell deathGO:00082191210.033
immune system processGO:00023762410.033
reproductionGO:0000003400.033
Worm
regulation of programmed cell deathGO:00430671010.033
neuronal action potentialGO:0019228180.033
apoptotic processGO:00069151160.033
eye developmentGO:00016542770.032
cellular ketone metabolic processGO:0042180110.032
negative regulation of cellular catabolic processGO:003133030.032
protein import into nucleusGO:000660630.032
vasculature developmentGO:00019442780.032
positive regulation of multicellular organismal processGO:0051240520.032
positive regulation of cellular catabolic processGO:003133130.032
positive regulation of cell cycleGO:004578730.032
regulation of cellular metabolic processGO:00313233200.032
i kappab kinase nf kappab signalingGO:000724940.031
organonitrogen compound metabolic processGO:1901564740.031
nuclear exportGO:005116810.031
programmed cell deathGO:00125011190.031
axon developmentGO:00615641660.030
digestive tract developmentGO:00485652650.030
segmentationGO:0035282970.030
ribonucleoside monophosphate catabolic processGO:000915840.030
cell cycleGO:0007049930.029
positive regulation of cellular amine metabolic processGO:003324000.029
heterocycle biosynthetic processGO:00181302150.029
cell cycle processGO:0022402530.029
formation of primary germ layerGO:0001704620.029
cellular response to stressGO:0033554620.029
maintenance of locationGO:005123540.029
multi organism processGO:00517041340.029
Worm
negative regulation of catabolic processGO:000989530.029
positive regulation of nitrogen compound metabolic processGO:0051173690.029
regenerationGO:0031099910.028
regulation of macromolecule metabolic processGO:00602553170.028
regulation of biosynthetic processGO:00098892500.027
cell cycle g1 s phase transitionGO:004484310.027
nuclear importGO:005117030.027
cellular amino acid metabolic processGO:000652070.026
nucleic acid transportGO:005065720.026
guanosine containing compound catabolic processGO:190106920.026
rna transportGO:005065820.026
nucleoside monophosphate catabolic processGO:000912540.026
positive regulation of cellular amino acid metabolic processGO:004576400.026
biosynthetic processGO:00090582940.026
neuroblast proliferationGO:000740520.026
protein metabolic processGO:00195381830.026
peripheral nervous system developmentGO:0007422550.026
multicellular organism reproductionGO:0032504350.026
Worm
regulation of primary metabolic processGO:00800903110.026
action potentialGO:0001508190.026
small molecule metabolic processGO:0044281770.025
mitotic dna damage checkpointGO:004477340.025
protein localization to nucleusGO:003450430.025
cellular component assemblyGO:00226071700.025
glial cell proliferationGO:001400940.025
establishment of protein localization to organelleGO:007259440.025
embryonic heart tube developmentGO:00350501330.025
regulation of nucleocytoplasmic transportGO:004682220.025
lateral line system developmentGO:0048925760.025
fertilizationGO:000956630.025
regulation of intracellular protein transportGO:003315730.024
regulation of cell developmentGO:00602841000.024
protein targeting to nucleusGO:004474430.024
central nervous system developmentGO:00074173870.024
single organism transportGO:00447652060.024
neuron projection developmentGO:00311751800.024
somitogenesisGO:0001756870.024
regulation of cytoplasmic transportGO:190364940.024
response to uvGO:000941130.024
regulation of protein import into nucleusGO:004230620.024
regulation of gene expressionGO:00104682650.024
rna biosynthetic processGO:00327741810.024
regulation of multicellular organismal processGO:00512392770.024
regulation of glial cell differentiationGO:004568540.023
response to radiationGO:0009314510.023
transmission of nerve impulseGO:0019226190.023
cellular response to radiationGO:007147840.023
anterior posterior pattern specificationGO:00099521520.023
head developmentGO:00603223030.023
regulation of purine nucleotide catabolic processGO:003312120.023
phosphate containing compound metabolic processGO:00067961080.023
stem cell maintenanceGO:001982740.023
cellular nitrogen compound metabolic processGO:00346412900.023
regulation of metabolic processGO:00192223590.023
multicellular organismal signalingGO:0035637220.023
embryonic heart tube morphogenesisGO:00031431080.023
cellular macromolecular complex assemblyGO:0034622240.023
tissue regenerationGO:0042246740.023
cellular protein modification processGO:00064641000.023
regulation of i kappab kinase nf kappab signalingGO:004312240.022
nucleic acid templated transcriptionGO:00976591810.022
regulation of synaptic growth at neuromuscular junctionGO:000858210.022
chordate embryonic developmentGO:00430092710.022
positive regulation of catabolic processGO:000989640.022
cell morphogenesis involved in differentiationGO:00009041950.022
notochord developmentGO:0030903540.022
forebrain developmentGO:0030900960.022
gtp catabolic processGO:000618420.022
oxoacid metabolic processGO:0043436310.022
cation transmembrane transportGO:0098655650.022
gastrulationGO:00073692080.022
cellular response to chemical stimulusGO:00708871570.022
skeletal muscle tissue developmentGO:0007519670.022
embryonic organ morphogenesisGO:00485622740.021
regulation of protein targetingGO:190353320.021
retina development in camera type eyeGO:00600411460.021
transportGO:00068102200.021
gtp metabolic processGO:004603940.021
negative regulation of nitrogen compound metabolic processGO:0051172590.021
regulation of nitrogen compound metabolic processGO:00511712510.021
membrane invaginationGO:001032410.021
macromolecule modificationGO:00434121110.021
negative regulation of cellular metabolic processGO:0031324770.021
sensory organ morphogenesisGO:00905962000.021
digestive system developmentGO:00551232890.021
mitotic cell cycle processGO:1903047480.021
intracellular transportGO:0046907320.020
female meiotic divisionGO:000714320.020
regulation of dendrite developmentGO:005077330.020
protein polymerizationGO:005125840.020
organic acid metabolic processGO:0006082310.020
macromolecular complex subunit organizationGO:0043933740.020
cilium organizationGO:0044782710.020
regulation of establishment of protein localizationGO:007020140.020
centrosome cycleGO:000709810.020
mitotic g2 dna damage checkpointGO:000709530.020
regulation of anatomical structure morphogenesisGO:00226031300.020
regulation of multicellular organism growthGO:004001440.020
cilium morphogenesisGO:0060271850.020
determination of bilateral symmetryGO:00098552040.019
cell cycle g2 m phase transitionGO:004483940.019
signal transductionGO:00071654550.019
cell projection organizationGO:00300302840.019
purine nucleoside monophosphate catabolic processGO:000912840.019
developmental growth involved in morphogenesisGO:0060560860.019
hepaticobiliary system developmentGO:0061008980.019
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.019
axonogenesisGO:00074091520.019
gland developmentGO:00487321430.019
endoderm developmentGO:0007492490.019
cartilage developmentGO:0051216960.019
protein acetylationGO:000647320.019
cellular response to extracellular stimulusGO:003166820.019
cytoskeleton dependent cytokinesisGO:006164030.019
response to transition metal nanoparticleGO:1990267280.019
regulation of reproductive processGO:200024140.019
positive regulation of map kinase activityGO:004340630.019
protein modification processGO:00362111000.019
regulation of protein transportGO:005122330.018
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.018
positive regulation of transportGO:005105020.018
regulation of response to stimulusGO:00485832690.018
purine ribonucleoside monophosphate catabolic processGO:000916940.018
organic cyclic compound biosynthetic processGO:19013622230.018
proteasomal protein catabolic processGO:001049820.018
protein acylationGO:004354330.018
protein phosphorylationGO:0006468470.017
regulation of rna biosynthetic processGO:20011412130.017
extrinsic apoptotic signaling pathwayGO:009719130.017
microtubule cytoskeleton organization involved in mitosisGO:190285010.017
tissue remodelingGO:004877140.017
muscle fiber developmentGO:0048747520.017
regulation of gtp catabolic processGO:003312420.017
meiosis iGO:000712710.017
positive regulation of cellular processGO:00485222010.017
regulation of cell differentiationGO:00455951420.017
neuron projection morphogenesisGO:00488121610.017
lateral line developmentGO:0048882660.017
rna export from nucleusGO:000640510.017
g2 m transition of mitotic cell cycleGO:000008640.017
g2 dna damage checkpointGO:003157230.017
astrocyte differentiationGO:004870810.017
cellular response to nutrient levelsGO:003166920.017
establishment of rna localizationGO:005123630.017
negative regulation of macromolecule metabolic processGO:0010605760.017
negative regulation of gliogenesisGO:001401410.017
negative regulation of chromosome organizationGO:200125110.017
negative regulation of cellular biosynthetic processGO:0031327550.016
regulation of protein catabolic processGO:004217610.016
regulation of macromolecule biosynthetic processGO:00105562250.016
ear developmentGO:00435831270.016
somatic stem cell maintenanceGO:003501910.016
positive regulation of cellular component biogenesisGO:004408930.016
regulation of mitotic cell cycleGO:0007346250.016
response to woundingGO:00096111160.016
neurotransmitter transportGO:000683620.016
protein homooligomerizationGO:005126030.016
angiogenesisGO:00015251580.016
camera type eye developmentGO:00430102220.016
cell substrate adhesionGO:003158940.016
carbohydrate homeostasisGO:003350010.016
skeletal muscle organ developmentGO:0060538780.016
regulation of nucleoside metabolic processGO:000911820.016
regulation of cell communicationGO:00106462320.016
urogenital system developmentGO:0001655970.016
digestive tract morphogenesisGO:00485462310.016
cranial nerve developmentGO:0021545420.016
regulation of cell shapeGO:000836010.016
regulation of apoptotic processGO:0042981980.016
regulation of epithelial cell proliferationGO:005067830.015
negative regulation of cell differentiationGO:0045596460.015
otic vesicle developmentGO:0071599420.015
negative regulation of signalingGO:0023057960.015
negative regulation of wnt signaling pathwayGO:0030178300.015
positive regulation of neuron deathGO:190121610.015
centrosome duplicationGO:005129810.015
sensory organ developmentGO:00074233930.015
cilium assemblyGO:0042384580.015
regulation of striated muscle contractionGO:000694220.015
actin cytoskeleton organizationGO:0030036630.015
regulation of axonogenesisGO:0050770320.015
positive regulation of purine nucleotide catabolic processGO:003312310.015
atp catabolic processGO:000620040.015
actomyosin structure organizationGO:0031032530.015
regulation of multicellular organismal developmentGO:20000262230.015
cellular response to reactive oxygen speciesGO:003461420.015
negative regulation of multicellular organismal processGO:0051241690.015
negative regulation of nucleic acid templated transcriptionGO:1903507450.015
regulation of intracellular signal transductionGO:1902531570.015
spindle assembly involved in meiosisGO:009030610.015
positive regulation of transcription dna templatedGO:0045893570.014
negative regulation of kinase activityGO:003367340.014
regulation of microtubule cytoskeleton organizationGO:007050730.014
regulation of nucleobase containing compound metabolic processGO:00192192500.014
cellular response to oxygen containing compoundGO:1901701200.014
neurological system processGO:0050877620.014
negative regulation of gene expressionGO:0010629650.014
muscle tissue developmentGO:00605371100.014
cognitionGO:005089010.014
autophagyGO:000691440.014
cellular localizationGO:0051641970.014
regulation of membrane potentialGO:0042391230.014
wnt signaling pathwayGO:0016055800.014
glial cell differentiationGO:0010001420.014
cellular amide metabolic processGO:004360340.014
adult behaviorGO:003053420.014
nucleobase containing compound transportGO:001593120.014
negative regulation of nucleobase containing compound metabolic processGO:0045934590.014
regulation of cell deathGO:00109411030.014
somite developmentGO:0061053960.014
erythrocyte maturationGO:004324980.014
cell projection assemblyGO:0030031640.014
inner ear developmentGO:00488391260.014
negative regulation of cell communicationGO:0010648960.014
epidermis developmentGO:0008544480.014
enzyme linked receptor protein signaling pathwayGO:00071671060.014
wound healingGO:0042060900.014
regulation of photoreceptor cell differentiationGO:004653220.014
epithelial tube morphogenesisGO:00605621480.014
pronuclear migrationGO:003504610.013
positive regulation of neuron apoptotic processGO:004352510.013
lipid storageGO:001991510.013
regulation of synapse organizationGO:005080730.013
neural crest cell migrationGO:0001755420.013
cellular response to organic substanceGO:00713101050.013
calcium ion transport into cytosolGO:006040230.013
meiotic spindle organizationGO:000021210.013
negative regulation of response to stimulusGO:00485851040.013
regulation of cellular macromolecule biosynthetic processGO:20001122220.013
protein stabilizationGO:005082120.013
ras protein signal transductionGO:000726570.013
neuron projection guidanceGO:0097485860.013
phagocytosis engulfmentGO:000691110.013
response to organic substanceGO:00100331530.013
trabecula morphogenesisGO:006138320.013
transmembrane transportGO:00550851200.013
inner ear morphogenesisGO:0042472630.013
regulation of jak stat cascadeGO:004642530.013
neuron projection extensionGO:1990138450.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.013
regulation of gtpase activityGO:004308720.013
compound eye developmentGO:004874920.013
exocytosisGO:000688710.013
regulation of protein localization to nucleusGO:190018020.013
proteolysis involved in cellular protein catabolic processGO:005160330.013
mesenchyme developmentGO:00604851270.013
regulation of signal transductionGO:00099662250.012
cellular carbohydrate metabolic processGO:004426240.012
response to oxygen containing compoundGO:1901700550.012
regulation of cytokine productionGO:000181730.012
notch signaling pathwayGO:0007219350.012
regulation of cell morphogenesisGO:0022604420.012
synaptic growth at neuromuscular junctionGO:005112420.012
regulation of cell cycleGO:0051726520.012
cell proliferationGO:0008283800.012
phosphorylationGO:0016310690.012
inorganic cation transmembrane transportGO:0098662500.012
regulation of bindingGO:005109830.012
inorganic ion transmembrane transportGO:0098660570.012
modification dependent macromolecule catabolic processGO:004363230.012
response to corticosteroidGO:003196010.012
retina morphogenesis in camera type eyeGO:0060042790.012
developmental cell growthGO:0048588520.012
regulation of reactive oxygen species metabolic processGO:200037720.012
peptide transportGO:001583310.012
metal ion transportGO:0030001580.012
regulation of sequestering of calcium ionGO:005128240.012
positive regulation of nucleotide catabolic processGO:003081310.012
circulatory system processGO:0003013870.012
eye morphogenesisGO:00485921440.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
response to carbohydrateGO:000974330.012
cardiac atrium developmentGO:000323040.012
positive regulation of gliogenesisGO:001401520.012
mesenchymal cell differentiationGO:0048762870.012
myeloid cell differentiationGO:0030099860.012
regulation of transcription dna templatedGO:00063552130.012
striated muscle tissue developmentGO:00147061100.012
ubiquitin dependent protein catabolic processGO:000651130.012
nuclear divisionGO:0000280230.012
negative regulation of protein phosphorylationGO:000193340.012
neurotransmitter secretionGO:000726920.012
b cell activationGO:004211320.012
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.012
neural crest cell developmentGO:0014032620.012
gliogenesisGO:0042063450.011
regulation of protein complex assemblyGO:004325430.011
regulation of mrna processingGO:005068430.011
anatomical structure arrangementGO:004853220.011
mrna processingGO:0006397140.011
ion transmembrane transportGO:0034220910.011
male meiosisGO:000714020.011
primary neural tube formationGO:001402010.011
protein localization to plasma membraneGO:007265910.011
determination of left right symmetryGO:00073681790.011
dorsal ventral pattern formationGO:00099531250.011
negative regulation of dna metabolic processGO:005105340.011
glucose homeostasisGO:004259310.011
regulation of erk1 and erk2 cascadeGO:007037240.011
cellular response to starvationGO:000926710.011
tube closureGO:006060610.011
regulation of dna replicationGO:000627530.011
blood circulationGO:0008015870.011
stem cell fate commitmentGO:004886510.011
germ line stem cell maintenanceGO:003071820.011
convergent extension involved in gastrulationGO:0060027710.011
cytokinesisGO:000091030.011
developmental programmed cell deathGO:001062340.011
nerve developmentGO:0021675450.011
erk1 and erk2 cascadeGO:007037140.011
glial cell developmentGO:0021782200.011
protein secretionGO:000930610.011
cation transportGO:0006812810.011
positive regulation of erk1 and erk2 cascadeGO:007037420.011
erythrocyte differentiationGO:0030218540.011
purine containing compound metabolic processGO:0072521290.011
dna metabolic processGO:0006259270.011
endosomal transportGO:001619720.011
positive regulation of muscle organ developmentGO:004863610.011
positive regulation of apoptotic processGO:0043065290.011
central nervous system neuron differentiationGO:0021953740.011
cellular response to xenobiotic stimulusGO:0071466350.011
regulation of cell substrate adhesionGO:001081010.011
positive regulation of nucleic acid templated transcriptionGO:1903508570.011
mitochondrial transportGO:000683920.011
posterior lateral line system developmentGO:0048915460.011
positive regulation of metabolic processGO:00098931080.011
negative regulation of chemotaxisGO:005092240.011
negative regulation of biosynthetic processGO:0009890550.011
microtubule polymerization or depolymerizationGO:003110930.011
myelinationGO:0042552180.011
negative regulation of transcription dna templatedGO:0045892450.010
chemotaxisGO:00069351040.010
regulation of cellular protein catabolic processGO:190336210.010
regulation of protein modification by small protein conjugation or removalGO:190332030.010
positive regulation of ras protein signal transductionGO:004657910.010
camera type eye morphogenesisGO:00485931080.010
regulation of ion transmembrane transporter activityGO:003241220.010
sequestering of metal ionGO:005123830.010
macromolecular complex assemblyGO:0065003350.010
symbiosis encompassing mutualism through parasitismGO:004440340.010
rna processingGO:0006396250.010
internal peptidyl lysine acetylationGO:001839320.010
ear morphogenesisGO:0042471640.010
regulation of oligodendrocyte differentiationGO:004871310.010
behaviorGO:0007610740.010
mesoderm formationGO:0001707430.010
positive regulation of rna biosynthetic processGO:1902680570.010
regulation of tube sizeGO:003515020.010
positive regulation of gtp catabolic processGO:003312610.010
regulation of stem cell differentiationGO:200073640.010

heatr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.031
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.014
immune system diseaseDOID:291400.013
organ system cancerDOID:005068600.012
nervous system diseaseDOID:86300.012