Danio rerio

22 known processes

hmgcs1

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)

(Aliases: zgc:56481,MGC56481)

hmgcs1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
small molecule metabolic processGO:0044281770.446
alcohol biosynthetic processGO:004616520.422
agingGO:000756820.361
organic cyclic compound metabolic processGO:19013603010.337
organic cyclic compound biosynthetic processGO:19013622230.295
hepaticobiliary system developmentGO:0061008980.293
larval developmentGO:000216420.290
Worm
oxoacid metabolic processGO:0043436310.267
skeletal system developmentGO:00015011810.260
nucleobase containing compound metabolic processGO:00061392740.253
cellular ketone metabolic processGO:0042180110.240
regulation of metabolic processGO:00192223590.234
nitrogen compound metabolic processGO:00068073190.206
cellular nitrogen compound biosynthetic processGO:00442712180.198
cellular nitrogen compound metabolic processGO:00346412900.196
heterocycle biosynthetic processGO:00181302150.187
regulation of nitrogen compound metabolic processGO:00511712510.186
negative regulation of protein complex assemblyGO:003133310.184
aromatic compound biosynthetic processGO:00194382170.181
negative regulation of cellular processGO:00485232830.180
response to stressGO:00069502630.170
generation of neuronsGO:00486993850.166
sensory organ developmentGO:00074233930.164
single organism metabolic processGO:00447102170.161
neuron differentiationGO:00301823530.159
organelle organizationGO:00069962270.155
organic acid metabolic processGO:0006082310.152
carboxylic acid metabolic processGO:0019752220.152
liver developmentGO:0001889960.152
cellular aromatic compound metabolic processGO:00067252950.145
regulation of nucleobase containing compound metabolic processGO:00192192500.136
regulation of cellular ketone metabolic processGO:001056570.134
response to external stimulusGO:00096052640.132
heterocycle metabolic processGO:00464832900.131
regulation of biological qualityGO:00650082630.129
single organism biosynthetic processGO:0044711710.128
gene expressionGO:00104672520.125
gland developmentGO:00487321430.120
establishment of localization in cellGO:0051649770.119
organic substance biosynthetic processGO:19015762890.111
negative regulation of biological processGO:00485193040.110
inner ear developmentGO:00488391260.108
cellular component morphogenesisGO:00329893360.104
embryonic organ morphogenesisGO:00485622740.104
cellular biosynthetic processGO:00442492860.104
locomotionGO:00400113130.102
Worm
regulation of gene expressionGO:00104682650.102
sensory organ morphogenesisGO:00905962000.101
brain developmentGO:00074202930.095
vasculature developmentGO:00019442780.094
regulation of macromolecule metabolic processGO:00602553170.094
cellular macromolecule biosynthetic processGO:00346452240.093
cellular localizationGO:0051641970.092
rna metabolic processGO:00160702190.091
signal transductionGO:00071654550.091
golgi vesicle transportGO:004819330.089
small molecule catabolic processGO:004428230.086
regulation of nucleic acid templated transcriptionGO:19035062130.086
regulation of response to stimulusGO:00485832690.085
biosynthetic processGO:00090582940.085
single organism transportGO:00447652060.084
nucleobase containing compound biosynthetic processGO:00346542050.083
nucleic acid metabolic processGO:00903042440.083
multicellular organism growthGO:003526440.083
organonitrogen compound metabolic processGO:1901564740.082
cellular component biogenesisGO:00440851780.081
regulation of developmental processGO:00507932470.080
regulation of protein complex assemblyGO:004325430.078
macromolecule biosynthetic processGO:00090592270.078
cellular response to extracellular stimulusGO:003166820.078
ear developmentGO:00435831270.078
cognitionGO:005089010.078
system processGO:00030081850.078
maintenance of locationGO:005123540.077
lipid biosynthetic processGO:0008610220.076
regulation of primary metabolic processGO:00800903110.076
establishment of localizationGO:00512342440.076
Worm
steroid biosynthetic processGO:000669450.074
cell part morphogenesisGO:00329902460.074
cellular macromolecule metabolic processGO:00442603910.073
cell surface receptor signaling pathwayGO:00071663250.073
positive regulation of biological processGO:00485182530.070
cell morphogenesis involved in neuron differentiationGO:00486671630.070
carboxylic acid biosynthetic processGO:0046394120.070
embryonic organ developmentGO:00485683810.066
response to nutrientGO:000758430.066
ear morphogenesisGO:0042471640.065
regulation of transcription from rna polymerase ii promoterGO:00063571140.065
cell deathGO:00082191210.065
neuron developmentGO:00486662620.064
determination of left right symmetryGO:00073681790.063
amine metabolic processGO:000930820.061
regulation of transcription dna templatedGO:00063552130.060
regulation of rna metabolic processGO:00512522240.060
central nervous system developmentGO:00074173870.059
negative regulation of cytoplasmic transportGO:190365020.059
negative regulation of developmental processGO:0051093650.058
blood vessel developmentGO:00015682460.058
regulation of cell communicationGO:00106462320.058
establishment of protein localization to organelleGO:007259440.058
positive regulation of nitrogen compound metabolic processGO:0051173690.057
fatty acid biosynthetic processGO:000663340.057
inositol lipid mediated signalingGO:004801720.056
cellular component movementGO:00069283350.056
response to organic substanceGO:00100331530.056
cellular amine metabolic processGO:004410620.056
regulation of biosynthetic processGO:00098892500.055
regulation of cellular biosynthetic processGO:00313262450.055
digestive system developmentGO:00551232890.054
macromolecular complex subunit organizationGO:0043933740.054
meiotic nuclear divisionGO:000712640.052
cell morphogenesisGO:00009022890.052
transcription dna templatedGO:00063511810.051
stem cell maintenanceGO:001982740.051
regulation of fatty acid metabolic processGO:001921710.051
determination of bilateral symmetryGO:00098552040.050
positive regulation of cellular processGO:00485222010.050
regulation of cellular metabolic processGO:00313233200.050
single organism organelle organizationGO:19025891990.050
lipid catabolic processGO:001604240.049
blood vessel morphogenesisGO:00485142160.049
nucleic acid templated transcriptionGO:00976591810.049
negative regulation of metabolic processGO:0009892860.047
stem cell proliferationGO:007208940.047
regulation of multicellular organism growthGO:004001440.047
regulation of rna biosynthetic processGO:20011412130.047
cell projection organizationGO:00300302840.047
neuron projection morphogenesisGO:00488121610.046
small molecule biosynthetic processGO:0044283160.046
cell morphogenesis involved in differentiationGO:00009041950.046
cellular response to nutrient levelsGO:003166920.046
transportGO:00068102200.045
Worm
er to golgi vesicle mediated transportGO:000688810.045
eye developmentGO:00016542770.044
response to drugGO:004249330.044
rna biosynthetic processGO:00327741810.044
synaptic growth at neuromuscular junctionGO:005112420.043
cellular component assemblyGO:00226071700.043
apoptotic processGO:00069151160.043
fatty acid metabolic processGO:000663150.043
epithelial cell differentiationGO:00308551160.042
lipid storageGO:001991510.042
embryo development ending in birth or egg hatchingGO:00097922710.042
Worm
localization within membraneGO:005166810.041
angiogenesisGO:00015251580.041
growthGO:00400071740.040
regulation of signalingGO:00230512350.039
phosphate containing compound metabolic processGO:00067961080.039
chemosensory behaviorGO:000763510.039
membrane organizationGO:0061024210.039
regulation of cytoplasmic transportGO:190364940.039
regulation of cellular macromolecule biosynthetic processGO:20001122220.038
cell projection morphogenesisGO:00488582440.038
cellular amino acid biosynthetic processGO:000865220.038
regulation of signal transductionGO:00099662250.037
positive regulation of transportGO:005105020.036
organic anion transportGO:0015711150.036
head developmentGO:00603223030.035
hematopoietic or lymphoid organ developmentGO:00485341910.035
cellular amino acid metabolic processGO:000652070.035
skeletal system morphogenesisGO:00487051020.035
regulation of cellular amine metabolic processGO:003323800.034
cation transmembrane transportGO:0098655650.034
guanosine containing compound metabolic processGO:190106840.034
transcription from rna polymerase ii promoterGO:0006366800.034
positive regulation of transcription dna templatedGO:0045893570.034
morphogenesis of an epitheliumGO:00020093330.034
negative regulation of protein phosphorylationGO:000193340.033
organic hydroxy compound biosynthetic processGO:190161760.033
axon developmentGO:00615641660.033
monoamine transportGO:001584410.032
gtp catabolic processGO:000618420.032
positive regulation of metabolic processGO:00098931080.032
positive regulation of cell cycleGO:004578730.032
negative regulation of intracellular transportGO:003238730.032
negative regulation of signalingGO:0023057960.032
camera type eye developmentGO:00430102220.032
adult behaviorGO:003053420.031
response to chemicalGO:00422213200.031
digestive tract developmentGO:00485652650.031
positive regulation of rna biosynthetic processGO:1902680570.031
connective tissue developmentGO:0061448990.031
cellular protein complex assemblyGO:0043623190.031
tube morphogenesisGO:00352393490.031
multi organism processGO:00517041340.031
organic acid biosynthetic processGO:0016053120.031
single organism membrane organizationGO:0044802200.031
ion transportGO:00068111140.030
negative regulation of cell differentiationGO:0045596460.030
negative regulation of cellular component organizationGO:0051129160.029
regulation of tube sizeGO:003515020.029
cellular response to external stimulusGO:007149620.029
homeostatic processGO:00425921420.029
transmission of nerve impulseGO:0019226190.029
germ line stem cell maintenanceGO:003071820.029
er nucleus signaling pathwayGO:000698420.029
monocarboxylic acid biosynthetic processGO:0072330120.029
dorsal ventral pattern formationGO:00099531250.029
positive regulation of catabolic processGO:000989640.029
regulation of multicellular organismal processGO:00512392770.028
gliogenesisGO:0042063450.028
guanosine containing compound catabolic processGO:190106920.028
ribonucleoside monophosphate catabolic processGO:000915840.028
regulation of synaptic plasticityGO:004816710.028
mitochondrion organizationGO:000700540.028
neurological system processGO:0050877620.028
nucleoside monophosphate catabolic processGO:000912540.028
modification dependent macromolecule catabolic processGO:004363230.028
protein complex assemblyGO:0006461300.028
regulation of cellular amino acid metabolic processGO:000652100.028
determination of heart left right asymmetryGO:00613711170.028
regulation of response to stressGO:0080134360.027
lipid metabolic processGO:0006629520.027
long chain fatty acid metabolic processGO:000167610.027
transmembrane transportGO:00550851200.027
regulation of cytokine productionGO:000181730.027
regulation of nucleoside metabolic processGO:000911820.027
regulation of apoptotic processGO:0042981980.026
heart developmentGO:00075073130.026
neuron projection developmentGO:00311751800.026
phosphorus metabolic processGO:00067931090.026
alcohol metabolic processGO:0006066110.026
protein complex biogenesisGO:0070271300.026
nuclear importGO:005117030.026
tissue remodelingGO:004877140.026
dicarboxylic acid metabolic processGO:004364810.025
gtp metabolic processGO:004603940.025
anion transportGO:0006820380.025
positive regulation of cellular metabolic processGO:0031325940.025
renal system developmentGO:0072001940.025
alpha amino acid metabolic processGO:190160530.025
regulation of peptidyl tyrosine phosphorylationGO:005073010.025
regulation of macromolecule biosynthetic processGO:00105562250.025
steroid metabolic processGO:000820270.025
positive regulation of nucleobase containing compound metabolic processGO:0045935690.025
hormone secretionGO:004687920.025
purine nucleoside monophosphate catabolic processGO:000912840.025
neurotransmitter secretionGO:000726920.024
cellular macromolecular complex assemblyGO:0034622240.024
positive regulation of cellular amine metabolic processGO:003324000.024
macromolecular complex assemblyGO:0065003350.024
enzyme linked receptor protein signaling pathwayGO:00071671060.024
regulation of intracellular signal transductionGO:1902531570.024
regulation of gtp catabolic processGO:003312420.024
nuclear transportGO:005116940.024
cellular response to organic substanceGO:00713101050.024
phosphatidylinositol 3 kinase signalingGO:001406520.024
monocarboxylic acid metabolic processGO:0032787170.024
positive regulation of macromolecule metabolic processGO:0010604930.024
negative regulation of kinase activityGO:003367340.024
negative regulation of cell communicationGO:0010648960.024
lateral line system developmentGO:0048925760.024
carboxylic acid catabolic processGO:004639530.023
nucleotide biosynthetic processGO:0009165210.023
proteolysis involved in cellular protein catabolic processGO:005160330.023
reproductionGO:0000003400.023
Worm
single organism localizationGO:19025782250.023
amino acid transportGO:000686520.023
regulation of ion transmembrane transporter activityGO:003241220.023
regulation of synaptic growth at neuromuscular junctionGO:000858210.023
regulation of metal ion transportGO:001095940.023
blood circulationGO:0008015870.023
regulation of blood vessel sizeGO:005088020.023
proteasomal protein catabolic processGO:001049820.023
regulation of transmembrane transporter activityGO:002289820.023
positive regulation of cellular biosynthetic processGO:0031328680.023
axonogenesisGO:00074091520.022
regulation of transporter activityGO:003240920.022
axon ensheathment in central nervous systemGO:003229120.022
regulation of extrinsic apoptotic signaling pathwayGO:200123630.022
deathGO:00162651210.022
circulatory system processGO:0003013870.022
phosphatidylinositol mediated signalingGO:004801520.022
positive regulation of rna metabolic processGO:0051254590.022
immune system processGO:00023762410.022
cellular modified amino acid metabolic processGO:000657530.022
organic substance catabolic processGO:1901575280.021
hormone transportGO:000991420.021
regulation of localizationGO:00328791040.021
bone developmentGO:0060348140.021
protein importGO:001703830.021
purine ribonucleoside monophosphate catabolic processGO:000916940.021
negative regulation of response to stimulusGO:00485851040.021
atp catabolic processGO:000620040.021
negative regulation of mapk cascadeGO:004340940.021
organonitrogen compound biosynthetic processGO:1901566470.021
sulfur compound transportGO:007234830.021
regulation of sodium ion transportGO:000202820.021
hemopoiesisGO:00300971830.020
tyrosine phosphorylation of stat proteinGO:000726010.020
regulation of sodium ion transmembrane transportGO:190230510.020
endosomal transportGO:001619720.020
positive regulation of cellular catabolic processGO:003133130.020
regulation of meiotic cell cycleGO:005144510.020
cellular lipid catabolic processGO:004424230.020
fatty acid transportGO:001590810.020
cellular response to stressGO:0033554620.020
lateral line developmentGO:0048882660.020
response to glucoseGO:000974930.019
glial cell differentiationGO:0010001420.019
single organism nuclear importGO:190259330.019
negative regulation of signal transductionGO:0009968940.019
regulation of blood pressureGO:000821710.019
sodium ion transmembrane transportGO:0035725210.019
negative regulation of protein kinase activityGO:000646940.019
positive regulation of nucleic acid templated transcriptionGO:1903508570.019
inner ear receptor cell differentiationGO:0060113290.019
response to hexoseGO:000974630.019
organelle assemblyGO:00709251100.019
inorganic cation transmembrane transportGO:0098662500.019
positive regulation of gene expressionGO:0010628710.019
specification of symmetryGO:00097992040.019
positive regulation of cellular amino acid metabolic processGO:004576400.018
forebrain developmentGO:0030900960.018
response to external biotic stimulusGO:0043207970.018
programmed cell deathGO:00125011190.018
autophagyGO:000691440.018
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.018
regulation of cell differentiationGO:00455951420.018
neuroblast proliferationGO:000740520.018
myeloid cell differentiationGO:0030099860.018
cellular component assembly involved in morphogenesisGO:00109271070.018
positive regulation of nucleoside metabolic processGO:004597910.018
phagocytosis engulfmentGO:000691110.018
synaptic vesicle localizationGO:009747910.018
cellular lipid metabolic processGO:0044255360.018
peptide metabolic processGO:000651810.018
organic acid catabolic processGO:001605430.018
cell cell signalingGO:0007267520.017
intracellular signal transductionGO:0035556850.017
neurotransmitter transportGO:000683620.017
meiotic cell cycle processGO:190304630.017
stem cell developmentGO:0048864820.017
muscle organ developmentGO:00075171010.017
regulation of myotube differentiationGO:001083020.017
regulation of epithelial cell proliferationGO:005067830.017
cellular component disassemblyGO:002241110.017
regulation of dendrite developmentGO:005077330.017
ion transmembrane transportGO:0034220910.017
cellular response to starvationGO:000926710.017
ubiquitin dependent protein catabolic processGO:000651130.017
multicellular organismal signalingGO:0035637220.017
stem cell differentiationGO:00488631170.017
synaptic vesicle recyclingGO:003646510.017
muscle tissue developmentGO:00605371100.017
catechol containing compound metabolic processGO:000971220.017
negative regulation of gene expressionGO:0010629650.016
regulation of gtpase activityGO:004308720.016
negative regulation of nucleocytoplasmic transportGO:004682320.016
response to acid chemicalGO:0001101170.016
embryonic skeletal system developmentGO:0048706970.016
regulation of programmed cell deathGO:00430671010.016
response to carbohydrateGO:000974330.016
epithelial tube morphogenesisGO:00605621480.016
neuronal action potentialGO:0019228180.016
heart morphogenesisGO:00030071560.016
cation transportGO:0006812810.016
bmp signaling pathwayGO:0030509520.016
developmental growthGO:00485891660.016
chemotaxisGO:00069351040.016
striated muscle tissue developmentGO:00147061100.016
cartilage developmentGO:0051216960.016
protein complex subunit organizationGO:0071822460.016
intracellular transportGO:0046907320.016
protein import into nucleusGO:000660630.016
cellular protein catabolic processGO:004425740.016
regulation of response to nutrient levelsGO:003210710.016
regulation of cell deathGO:00109411030.016
immune system developmentGO:00025201910.016
actin filament based processGO:0030029640.016
long chain fatty acid transportGO:001590910.016
mesenchyme developmentGO:00604851270.016
organic hydroxy compound metabolic processGO:1901615160.016
regulation of neural precursor cell proliferationGO:200017730.016
response to uvGO:000941130.016
mechanoreceptor differentiationGO:0042490370.015
regulation of dendrite morphogenesisGO:004881430.015
protein targeting to nucleusGO:004474430.015
phagocytosisGO:000690930.015
purine ribonucleoside biosynthetic processGO:004612920.015
cilium morphogenesisGO:0060271850.015
nucleocytoplasmic transportGO:000691340.015
phosphorylationGO:0016310690.015
vesicle organizationGO:001605060.015
regulation of system processGO:0044057400.015
regulation of membrane potentialGO:0042391230.015
superoxide metabolic processGO:000680120.015
regulation of nucleotide catabolic processGO:003081120.015
response to topologically incorrect proteinGO:003596620.015
regulation of hormone secretionGO:004688320.015
taxisGO:00423301090.015
positive regulation of nucleotide catabolic processGO:003081310.015
single organism cellular localizationGO:1902580460.015
peptide transportGO:001583310.015
regulation of glial cell differentiationGO:004568540.015
regulation of bindingGO:005109830.015
anion transmembrane transportGO:0098656120.015
cellular response to chemical stimulusGO:00708871570.015
catabolic processGO:0009056320.015
protein acetylationGO:000647320.015
regulation of protein ubiquitinationGO:003139630.015
regulation of autophagyGO:001050630.015
dicarboxylic acid transportGO:000683510.015
positive regulation of purine nucleotide catabolic processGO:003312310.015
protein localization to nucleusGO:003450430.014
regulation of cellular component organizationGO:0051128860.014
behaviorGO:0007610740.014
nucleoside phosphate metabolic processGO:0006753280.014
modification dependent protein catabolic processGO:001994130.014
negative regulation of synapse assemblyGO:005196420.014
embryonic heart tube morphogenesisGO:00031431080.014
posterior lateral line developmentGO:0048916380.014
macromolecule localizationGO:0033036540.014
regulation of purine nucleotide catabolic processGO:003312120.014
cellular nitrogen compound catabolic processGO:0044270150.014
zymogen activationGO:003163830.014
cell motilityGO:00488702440.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
leukocyte proliferationGO:007066110.014
cellular protein metabolic processGO:00442671290.014
nucleoside biosynthetic processGO:000916320.014
regulation of cell growthGO:0001558290.014
gastrulationGO:00073692080.014
compound eye developmentGO:004874920.014
regulation of circadian rhythmGO:004275240.014
regulation of synapse assemblyGO:005196330.014
carbohydrate biosynthetic processGO:001605110.014
mechanosensory lateral line system developmentGO:0048881490.014
fin developmentGO:0033333770.014
action potentialGO:0001508190.013
establishment of synaptic vesicle localizationGO:009748010.013
chordate embryonic developmentGO:00430092710.013
glucose homeostasisGO:004259310.013
regulation of phosphate metabolic processGO:0019220430.013
protein homooligomerizationGO:005126030.013
response to biotic stimulusGO:0009607970.013
muscle structure developmentGO:00610611960.013
regulation of lipid biosynthetic processGO:004689080.013
response to monosaccharideGO:003428430.013
regulation of bmp signaling pathwayGO:0030510390.013
regulation of neuronal synaptic plasticityGO:004816810.013
sensory system developmentGO:0048880760.013
regulation of mrna processingGO:005068430.013
synaptic vesicle endocytosisGO:004848810.013
hindbrain developmentGO:0030902910.013
regulation of reactive oxygen species metabolic processGO:200037720.013
regulation of protein modification by small protein conjugation or removalGO:190332030.013
synaptic vesicle transportGO:004848910.013
central nervous system neuron differentiationGO:0021953740.013
regulation of synapse organizationGO:005080730.013
cell migrationGO:00164772370.013
metal ion transportGO:0030001580.013
aromatic compound catabolic processGO:0019439150.013
negative regulation of cytokine productionGO:000181810.013
medulla oblongata developmentGO:002155040.013
positive regulation of gtpase activityGO:004354710.013
posterior lateral line system developmentGO:0048915460.013
glial cell migrationGO:000834730.013
calcium ion importGO:007050940.013
negative regulation of defense responseGO:003134820.013
positive regulation of secretionGO:005104710.013
skeletal muscle tissue developmentGO:0007519670.013
positive regulation of macromolecule biosynthetic processGO:0010557590.013
neuron projection guidanceGO:0097485860.013
negative regulation of protein serine threonine kinase activityGO:007190120.013
monocarboxylic acid catabolic processGO:007232930.013
organic acid transportGO:001584990.013
rna localizationGO:000640340.013
regulation of phGO:000688530.013
hormone biosynthetic processGO:004244630.012
regulation of erk1 and erk2 cascadeGO:007037240.012
carbohydrate homeostasisGO:003350010.012
neuromast developmentGO:0048884460.012
cellular carbohydrate metabolic processGO:004426240.012
negative regulation of epithelial cell proliferationGO:005068010.012
regulation of reproductive processGO:200024140.012
negative regulation of cellular biosynthetic processGO:0031327550.012
regulation of multicellular organismal developmentGO:20000262230.012
lipid oxidationGO:003444010.012
cell proliferationGO:0008283800.012
positive regulation of secretion by cellGO:190353210.012
protein stabilizationGO:005082120.012
entrainment of circadian clockGO:000964920.012
peptidyl serine phosphorylationGO:001810510.012
production of molecular mediator of immune responseGO:000244020.012
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.012
regenerationGO:0031099910.012

hmgcs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.059
disease of metabolismDOID:001466700.026
inherited metabolic disorderDOID:65500.025
nervous system diseaseDOID:86300.020
cancerDOID:16200.014
disease of cellular proliferationDOID:1456600.014
myopathyDOID:42300.012
muscle tissue diseaseDOID:6600.012
muscular diseaseDOID:008000000.012
musculoskeletal system diseaseDOID:1700.012