Danio rerio

21 known processes

rock2b

rho-associated, coiled-coil containing protein kinase 2b

(Aliases: si:dkey-65b13.10,si:dkey-65b13.7,cb64,sb:cb64)

rock2b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
tube morphogenesisGO:00352393490.342
Zebrafish Mouse Fly
carbohydrate derivative metabolic processGO:1901135610.259
kupffer s vesicle developmentGO:0070121500.197
heart developmentGO:00075073130.151
determination of bilateral symmetryGO:00098552040.130
regulation of nervous system developmentGO:0051960900.113
Fly
negative regulation of biological processGO:00485193040.107
Human Fly
cell part morphogenesisGO:00329902460.100
Mouse Fly
organelle organizationGO:00069962270.092
Human Zebrafish Mouse Fly
regulation of neurological system processGO:003164420.084
specification of symmetryGO:00097992040.081
carbohydrate derivative biosynthetic processGO:1901137430.079
embryonic organ developmentGO:00485683810.068
protein modification processGO:00362111000.067
Human Fly
cellular component assemblyGO:00226071700.064
Fly
locomotionGO:00400113130.061
Zebrafish Worm
single organism biosynthetic processGO:0044711710.058
regulation of nitrogen compound metabolic processGO:00511712510.056
chordate embryonic developmentGO:00430092710.054
Mouse
regulation of macromolecule metabolic processGO:00602553170.050
Fly
regulation of blood coagulationGO:003019310.050
digestive tract morphogenesisGO:00485462310.050
Zebrafish Fly
cilium organizationGO:0044782710.048
digestive system developmentGO:00551232890.043
Zebrafish Fly
cellular aromatic compound metabolic processGO:00067252950.042
signal transductionGO:00071654550.040
Zebrafish Mouse Rat Fly
cell morphogenesisGO:00009022890.040
Mouse Worm Fly
biosynthetic processGO:00090582940.040
cellular protein modification processGO:00064641000.039
Human Fly
cellular biosynthetic processGO:00442492860.037
protein metabolic processGO:00195381830.036
Human Zebrafish Fly
regulation of anatomical structure morphogenesisGO:00226031300.035
Human Zebrafish Worm Fly
nitrogen compound metabolic processGO:00068073190.035
neuron differentiationGO:00301823530.035
Mouse Fly
angiogenesisGO:00015251580.034
Human
cellular component biogenesisGO:00440851780.034
Fly
nucleic acid metabolic processGO:00903042440.033
anatomical structure arrangementGO:004853220.033
determination of left right symmetryGO:00073681790.032
stem cell fate commitmentGO:004886510.032
regulation of nucleotide catabolic processGO:003081120.032
membrane lipid biosynthetic processGO:004646720.031
lipid storageGO:001991510.029
cilium movementGO:0003341260.029
cell surface receptor signaling pathwayGO:00071663250.029
Zebrafish Mouse Fly
muscle cell developmentGO:00550011150.029
regulation of rna metabolic processGO:00512522240.029
sphingolipid biosynthetic processGO:003014820.029
phagocytosis engulfmentGO:000691110.028
regulation of neurogenesisGO:0050767870.028
Fly
cellular nitrogen compound biosynthetic processGO:00442712180.028
cell projection assemblyGO:0030031640.027
neuroblast differentiationGO:001401610.027
organelle assemblyGO:00709251100.027
small gtpase mediated signal transductionGO:000726480.027
Rat Fly
glycoprotein biosynthetic processGO:0009101210.027
positive regulation of cellular component biogenesisGO:004408930.026
Fly
rhombomere 5 morphogenesisGO:002166410.026
ras protein signal transductionGO:000726570.025
Rat Fly
cell projection organizationGO:00300302840.025
Mouse Fly
cellular macromolecule metabolic processGO:00442603910.025
Human Zebrafish Fly
gene expressionGO:00104672520.025
modification dependent protein catabolic processGO:001994130.025
guanosine containing compound metabolic processGO:190106840.025
regulation of gene expressionGO:00104682650.024
vasculature developmentGO:00019442780.024
Human
regulation of purine nucleotide catabolic processGO:003312120.024
regulation of cell projection organizationGO:0031344440.024
Fly
cellular component morphogenesisGO:00329893360.024
Mouse Worm Fly
blood vessel morphogenesisGO:00485142160.024
Human
heterocycle biosynthetic processGO:00181302150.023
regulation of primary metabolic processGO:00800903110.023
Fly
organic cyclic compound metabolic processGO:19013603010.023
negative regulation of protein phosphorylationGO:000193340.023
blood vessel developmentGO:00015682460.023
Human
transcription from rna polymerase ii promoterGO:0006366800.022
epibolyGO:0090504410.022
localization of cellGO:00516742440.022
Zebrafish Worm
otolith formationGO:003247520.021
response to chemicalGO:00422213200.021
cilium morphogenesisGO:0060271850.021
regulation of angiogenesisGO:0045765260.021
Human
intracellular receptor signaling pathwayGO:0030522300.021
regulation of protein ubiquitinationGO:003139630.021
organic substance biosynthetic processGO:19015762890.021
nucleobase containing compound biosynthetic processGO:00346542050.020
response to vitamin b3GO:003355220.020
steroid hormone mediated signaling pathwayGO:004340190.020
monoamine transportGO:001584410.019
negative regulation of protein transportGO:005122430.019
Fly
defense responseGO:0006952470.019
developmental growthGO:00485891660.019
Fly
larval developmentGO:000216420.019
Worm
guanosine containing compound catabolic processGO:190106920.019
positive regulation of metabolic processGO:00098931080.019
cell projection morphogenesisGO:00488582440.019
Mouse Fly
regulation of rna biosynthetic processGO:20011412130.019
phagocytosisGO:000690930.018
single organism membrane fusionGO:004480120.018
regulation of anatomical structure sizeGO:0090066330.018
adult behaviorGO:003053420.018
macromolecule biosynthetic processGO:00090592270.018
rna metabolic processGO:00160702190.018
negative regulation of response to stimulusGO:00485851040.017
spindle assemblyGO:005122520.017
aromatic compound biosynthetic processGO:00194382170.017
lymph vessel morphogenesisGO:0036303250.017
cellular response to endogenous stimulusGO:0071495680.017
regulation of biosynthetic processGO:00098892500.017
regulation of erk1 and erk2 cascadeGO:007037240.017
regulation of multicellular organismal processGO:00512392770.017
Human Zebrafish Fly
erk1 and erk2 cascadeGO:007037140.016
positive regulation of erk1 and erk2 cascadeGO:007037420.016
regulation of blood circulationGO:1903522320.016
gtp metabolic processGO:004603940.016
epithelial cell morphogenesisGO:000338220.016
Fly
regulation of nucleoside metabolic processGO:000911820.016
rhombomere boundary formationGO:0021654100.016
cellular protein catabolic processGO:004425740.016
Zebrafish
regulation of nucleotide metabolic processGO:0006140170.015
response to light stimulusGO:0009416460.015
regulation of hemostasisGO:190004610.015
cell migration involved in gastrulationGO:0042074790.015
Zebrafish
cellular protein metabolic processGO:00442671290.015
Human Zebrafish Fly
regulation of nucleobase containing compound metabolic processGO:00192192500.015
intracellular estrogen receptor signaling pathwayGO:003052030.015
rna biosynthetic processGO:00327741810.015
regulation of transcription dna templatedGO:00063552130.014
urogenital system developmentGO:0001655970.014
nuclear transportGO:005116940.014
cell motilityGO:00488702440.014
Zebrafish Worm
negative regulation of stem cell differentiationGO:200073720.014
positive regulation of catabolic processGO:000989640.014
cilium assemblyGO:0042384580.014
regulation of macromolecule biosynthetic processGO:00105562250.014
cellular nitrogen compound metabolic processGO:00346412900.014
cognitionGO:005089010.014
regulation of neuron differentiationGO:0045664560.014
Fly
membrane invaginationGO:001032410.014
regulation of cell activationGO:005086510.013
glomerular epithelium developmentGO:0072010120.013
regulation of gtp catabolic processGO:003312420.013
establishment of localizationGO:00512342440.013
Fly
actin filament based movementGO:003004810.013
Fly
nuclear importGO:005117030.013
regulation of gtpase activityGO:004308720.013
positive regulation of locomotionGO:0040017140.012
regulation of protein modification by small protein conjugation or removalGO:190332030.012
neuroblast proliferationGO:000740520.012
cell substrate adhesionGO:003158940.012
cell migrationGO:00164772370.012
Zebrafish Worm
nucleobase containing compound metabolic processGO:00061392740.012
regulation of cellular biosynthetic processGO:00313262450.012
negative regulation of signal transductionGO:0009968940.012
single organism metabolic processGO:00447102170.012
regulation of signal transductionGO:00099662250.012
Fly
regulation of protein complex assemblyGO:004325430.012
cellular response to chemical stimulusGO:00708871570.012
neuroblast fate commitmentGO:001401710.012
cellular component disassemblyGO:002241110.012
striated muscle cell developmentGO:00550021080.012
regulation of metabolic processGO:00192223590.012
Fly
regulation of transcription from rna polymerase ii promoterGO:00063571140.012
ameboidal type cell migrationGO:00016671430.012
Zebrafish
autophagyGO:000691440.012
female sex differentiationGO:004666040.012
synaptic vesicle localizationGO:009747910.012
cellular lipid metabolic processGO:0044255360.012
cell substrate junction assemblyGO:000704420.012
heterocycle metabolic processGO:00464832900.011
regulation of protein catabolic processGO:004217610.011
macromolecule localizationGO:0033036540.011
Fly
macromolecule modificationGO:00434121110.011
Human Fly
regulation of dendrite developmentGO:005077330.011
regulation of cytokine productionGO:000181730.011
taxisGO:00423301090.011
cellular macromolecule biosynthetic processGO:00346452240.011
embryonic organ morphogenesisGO:00485622740.011
transcription dna templatedGO:00063511810.011
morphogenesis of an epitheliumGO:00020093330.011
Zebrafish Mouse Fly
hindbrain developmentGO:0030902910.011
cellular component maintenanceGO:004395430.011
cardiac muscle cell differentiationGO:0055007300.011
organonitrogen compound biosynthetic processGO:1901566470.011
neuron projection developmentGO:00311751800.011
Mouse Fly
regulation of nucleic acid templated transcriptionGO:19035062130.011
modification dependent macromolecule catabolic processGO:004363230.011
system processGO:00030081850.011
regulation of cellular macromolecule biosynthetic processGO:20001122220.011
regulation of cell shapeGO:000836010.010
Worm Fly
negative regulation of protein kinase activityGO:000646940.010
cerebellum formationGO:002158820.010
notch signaling pathwayGO:0007219350.010
regulation of cell morphogenesis involved in differentiationGO:0010769380.010
Fly
rhombomere 5 developmentGO:002157140.010
negative regulation of macromolecule metabolic processGO:0010605760.010
long chain fatty acid biosynthetic processGO:004275910.010

rock2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
nervous system diseaseDOID:86300.022