Danio rerio

28 known processes

hsp70

heat shock cognate 70-kd protein

(Aliases: hsp70-4,hspa1a)

hsp70 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sensory organ developmentGO:00074233930.464
eye developmentGO:00016542770.412
response to chemicalGO:00422213200.346
response to arsenic containing substanceGO:004668550.204
monoamine transportGO:001584410.199
sensory organ morphogenesisGO:00905962000.181
response to transition metal nanoparticleGO:1990267280.162
nucleic acid metabolic processGO:00903042440.144
nucleobase containing compound metabolic processGO:00061392740.133
eye morphogenesisGO:00485921440.127
central nervous system developmentGO:00074173870.126
nitrogen compound metabolic processGO:00068073190.118
cellular response to lipopolysaccharideGO:007122230.108
heterocycle metabolic processGO:00464832900.106
agingGO:000756820.105
cellular biosynthetic processGO:00442492860.102
regulation of cellular metabolic processGO:00313233200.098
negative regulation of biological processGO:00485193040.094
ion transportGO:00068111140.091
brain developmentGO:00074202930.091
regulation of biological qualityGO:00650082630.090
cellular response to chemical stimulusGO:00708871570.088
membrane hyperpolarizationGO:006008110.088
negative regulation of cellular processGO:00485232830.088
cellular macromolecule metabolic processGO:00442603910.086
regulation of metabolic processGO:00192223590.086
organic substance biosynthetic processGO:19015762890.086
nucleobase containing compound biosynthetic processGO:00346542050.085
protein localization to nucleusGO:003450430.085
muscle structure developmentGO:00610611960.085
cellular aromatic compound metabolic processGO:00067252950.082
response to external stimulusGO:00096052640.081
camera type eye developmentGO:00430102220.079
regulation of primary metabolic processGO:00800903110.077
peptidyl serine phosphorylationGO:001810510.076
adult behaviorGO:003053420.076
neuron developmentGO:00486662620.076
larval developmentGO:000216420.076
neuron differentiationGO:00301823530.075
cellular nitrogen compound metabolic processGO:00346412900.075
regulation of biosynthetic processGO:00098892500.075
i kappab kinase nf kappab signalingGO:000724940.074
regulation of signal transductionGO:00099662250.071
single organism transportGO:00447652060.070
head developmentGO:00603223030.070
regulation of macromolecule metabolic processGO:00602553170.068
signal transductionGO:00071654550.067
regulation of nucleobase containing compound metabolic processGO:00192192500.065
regulation of cell communicationGO:00106462320.064
regulation of rna metabolic processGO:00512522240.063
response to stressGO:00069502630.062
ion transmembrane transportGO:0034220910.062
positive regulation of transportGO:005105020.061
anion transmembrane transportGO:0098656120.060
positive regulation of cellular metabolic processGO:0031325940.060
neuron neuron synaptic transmissionGO:000727010.060
regulation of signalingGO:00230512350.059
transcription dna templatedGO:00063511810.059
regulation of protein transportGO:005122330.058
biosynthetic processGO:00090582940.058
positive regulation of biological processGO:00485182530.057
single organism localizationGO:19025782250.057
gene expressionGO:00104672520.057
liver developmentGO:0001889960.056
aromatic compound biosynthetic processGO:00194382170.056
single organism metabolic processGO:00447102170.056
cellular response to organic substanceGO:00713101050.056
regulation of gene expressionGO:00104682650.055
response to organic substanceGO:00100331530.055
regulation of protein localization to nucleusGO:190018020.055
regulation of nitrogen compound metabolic processGO:00511712510.054
transmembrane transportGO:00550851200.053
amino acid transportGO:000686520.053
negative regulation of response to stimulusGO:00485851040.052
retina development in camera type eyeGO:00600411460.052
organic cyclic compound biosynthetic processGO:19013622230.052
response to xenobiotic stimulusGO:0009410450.052
gtp metabolic processGO:004603940.051
erythrocyte homeostasisGO:0034101550.051
cation transportGO:0006812810.051
protein modification processGO:00362111000.051
response to hormoneGO:0009725480.049
carboxylic acid metabolic processGO:0019752220.049
axon developmentGO:00615641660.049
establishment of localizationGO:00512342440.049
regulation of nucleic acid templated transcriptionGO:19035062130.048
regulation of transcription dna templatedGO:00063552130.048
apoptotic processGO:00069151160.048
regulation of intracellular protein transportGO:003315730.048
regionalizationGO:00030022740.048
regulation of establishment of protein localizationGO:007020140.048
programmed cell deathGO:00125011190.047
regulation of multicellular organismal processGO:00512392770.047
response to abiotic stimulusGO:00096281220.047
generation of neuronsGO:00486993850.047
regulation of transcription from rna polymerase ii promoterGO:00063571140.047
cellular response to lipidGO:0071396390.047
phagocytosisGO:000690930.046
organic cyclic compound metabolic processGO:19013603010.046
system processGO:00030081850.046
cellular response to external stimulusGO:007149620.046
gland developmentGO:00487321430.046
erythrocyte differentiationGO:0030218540.046
organic hydroxy compound transportGO:0015850140.045
heterocycle biosynthetic processGO:00181302150.045
positive regulation of cellular catabolic processGO:003133130.044
regulation of developmental processGO:00507932470.044
cellular macromolecule biosynthetic processGO:00346452240.043
regulation of macromolecule biosynthetic processGO:00105562250.042
cellular response to endogenous stimulusGO:0071495680.042
response to amino acidGO:004320020.042
negative regulation of programmed cell deathGO:0043069580.041
cellular response to organic cyclic compoundGO:0071407380.041
positive regulation of nitrogen compound metabolic processGO:0051173690.041
transcription from rna polymerase ii promoterGO:0006366800.041
regulation of protein catabolic processGO:004217610.041
regulation of i kappab kinase nf kappab signalingGO:004312240.040
regulation of cellular biosynthetic processGO:00313262450.040
regulation of cell differentiationGO:00455951420.040
cation transmembrane transportGO:0098655650.039
positive regulation of catabolic processGO:000989640.039
regulation of nucleoside metabolic processGO:000911820.039
regulation of cell deathGO:00109411030.039
ubiquitin dependent protein catabolic processGO:000651130.039
embryonic organ developmentGO:00485683810.038
modification dependent protein catabolic processGO:001994130.037
response to inorganic substanceGO:0010035380.037
determination of left right symmetryGO:00073681790.037
regulation of reactive oxygen species metabolic processGO:200037720.037
macromolecule biosynthetic processGO:00090592270.037
positive regulation of cell cycleGO:004578730.037
regulation of metal ion transportGO:001095940.037
localization of cellGO:00516742440.037
negative regulation of metabolic processGO:0009892860.037
regulation of cytokine productionGO:000181730.037
cell surface receptor signaling pathwayGO:00071663250.036
hepaticobiliary system developmentGO:0061008980.036
protein metabolic processGO:00195381830.036
nucleic acid templated transcriptionGO:00976591810.036
positive regulation of gtp catabolic processGO:003312610.036
regulation of membrane potentialGO:0042391230.036
guanosine containing compound catabolic processGO:190106920.035
regulation of apoptotic processGO:0042981980.035
retina morphogenesis in camera type eyeGO:0060042790.035
cellular component morphogenesisGO:00329893360.035
cellular response to biotic stimulusGO:007121630.035
regulation of rna biosynthetic processGO:20011412130.035
hematopoietic or lymphoid organ developmentGO:00485341910.035
response to drugGO:004249330.035
extrinsic apoptotic signaling pathwayGO:009719130.034
nuclear transportGO:005116940.034
response to endogenous stimulusGO:0009719830.034
positive regulation of nucleoside metabolic processGO:004597910.034
rna biosynthetic processGO:00327741810.034
cell part morphogenesisGO:00329902460.033
embryonic organ morphogenesisGO:00485622740.033
response to nutrientGO:000758430.033
modification dependent macromolecule catabolic processGO:004363230.033
cell deathGO:00082191210.033
regulation of cytoplasmic transportGO:190364940.033
proteolysis involved in cellular protein catabolic processGO:005160330.033
regulation of extrinsic apoptotic signaling pathwayGO:200123630.033
positive regulation of cellular processGO:00485222010.033
somatic muscle developmentGO:000752540.033
negative regulation of protein phosphorylationGO:000193340.033
positive regulation of macromolecule metabolic processGO:0010604930.032
mitochondrion organizationGO:000700540.032
regulation of molecular functionGO:0065009700.031
maintenance of locationGO:005123540.031
forebrain developmentGO:0030900960.031
negative regulation of macromolecule metabolic processGO:0010605760.031
amine metabolic processGO:000930820.031
cell morphogenesisGO:00009022890.031
rna metabolic processGO:00160702190.031
organonitrogen compound metabolic processGO:1901564740.030
response to cadmium ionGO:0046686140.030
deathGO:00162651210.029
transportGO:00068102200.029
cellular protein catabolic processGO:004425740.029
morphogenesis of an epitheliumGO:00020093330.029
positive regulation of metabolic processGO:00098931080.029
hindbrain developmentGO:0030902910.029
heart developmentGO:00075073130.029
nucleocytoplasmic transportGO:000691340.029
cellular nitrogen compound biosynthetic processGO:00442712180.029
regulation of cellular component organizationGO:0051128860.028
synaptic transmission glycinergicGO:006001210.028
cellular component assemblyGO:00226071700.028
multicellular organism growthGO:003526440.028
cellular amino acid metabolic processGO:000652070.028
regulation of multicellular organismal developmentGO:20000262230.028
positive regulation of i kappab kinase nf kappab signalingGO:004312330.028
phosphate containing compound metabolic processGO:00067961080.027
regulation of nucleocytoplasmic transportGO:004682220.027
reactive oxygen species biosynthetic processGO:190340910.027
guanosine containing compound metabolic processGO:190106840.027
negative regulation of protein transportGO:005122430.027
regulation of transportGO:0051049450.027
oxoacid metabolic processGO:0043436310.027
cellular response to molecule of bacterial originGO:007121930.026
peptidyl serine modificationGO:001820920.026
cellular amine metabolic processGO:004410620.026
chordate embryonic developmentGO:00430092710.026
behaviorGO:0007610740.026
regulation of response to stimulusGO:00485832690.026
protein secretionGO:000930610.026
nitrogen compound transportGO:0071705230.026
positive regulation of nucleobase containing compound metabolic processGO:0045935690.026
immune system processGO:00023762410.025
homeostatic processGO:00425921420.025
cell migrationGO:00164772370.025
nuclear importGO:005117030.025
cellular response to hormone stimulusGO:0032870390.025
eye photoreceptor cell differentiationGO:0001754450.024
regulation of dna recombinationGO:000001820.024
cellular ketone metabolic processGO:0042180110.024
digestive system developmentGO:00551232890.024
negative regulation of cellular metabolic processGO:0031324770.024
long chain fatty acid metabolic processGO:000167610.024
single organism biosynthetic processGO:0044711710.024
transmission of nerve impulseGO:0019226190.024
negative regulation of nucleocytoplasmic transportGO:004682320.024
specification of symmetryGO:00097992040.024
cellular localizationGO:0051641970.024
regulation of programmed cell deathGO:00430671010.024
negative regulation of dna metabolic processGO:005105340.024
blood vessel morphogenesisGO:00485142160.024
myeloid cell homeostasisGO:0002262560.024
regulation of system processGO:0044057400.024
small molecule metabolic processGO:0044281770.024
regulation of cellular macromolecule biosynthetic processGO:20001122220.024
positive regulation of cytokine productionGO:000181920.023
neural retina developmentGO:0003407490.023
phagocytosis engulfmentGO:000691110.023
determination of heart left right asymmetryGO:00613711170.023
regulation of bindingGO:005109830.023
positive regulation of purine nucleotide catabolic processGO:003312310.023
regulation of cellular amine metabolic processGO:003323800.023
stem cell proliferationGO:007208940.023
regulation of cellular protein catabolic processGO:190336210.022
negative regulation of apoptotic processGO:0043066550.022
axonogenesisGO:00074091520.022
regulation of nucleotide catabolic processGO:003081120.022
lipid storageGO:001991510.022
regulation of cellular protein metabolic processGO:0032268520.022
cell projection morphogenesisGO:00488582440.022
negative regulation of nucleobase containing compound metabolic processGO:0045934590.021
blood vessel developmentGO:00015682460.021
response to monosaccharideGO:003428430.021
neurological system processGO:0050877620.021
regulation of protein modification by small protein conjugation or removalGO:190332030.021
regulation of protein targetingGO:190353320.021
organelle organizationGO:00069962270.021
protein targeting to nucleusGO:004474430.021
intracellular signal transductionGO:0035556850.021
immune system developmentGO:00025201910.021
regulation of gtp catabolic processGO:003312420.021
action potentialGO:0001508190.021
neuron projection morphogenesisGO:00488121610.021
positive regulation of dna metabolic processGO:005105410.021
regulation of purine nucleotide catabolic processGO:003312120.021
cellular component movementGO:00069283350.021
regulation of neurogenesisGO:0050767870.021
homeostasis of number of cellsGO:0048872620.020
response to uvGO:000941130.020
locomotory behaviorGO:0007626340.020
regulation of inflammatory responseGO:005072720.020
negative regulation of nitrogen compound metabolic processGO:0051172590.020
regulation of reproductive processGO:200024140.020
response to hydrogen peroxideGO:004254230.020
positive regulation of inflammatory responseGO:005072910.020
response to glucoseGO:000974930.020
gtp catabolic processGO:000618420.020
protein localizationGO:0008104400.020
cell motilityGO:00488702440.020
stem cell divisionGO:001714510.020
monovalent inorganic cation transportGO:0015672420.020
neurotransmitter transportGO:000683620.020
regulation of inhibitory postsynaptic membrane potentialGO:006008010.020
lens development in camera type eyeGO:0002088220.019
lymph vessel developmentGO:0001945270.019
regulation of synaptic plasticityGO:004816710.019
macromolecule modificationGO:00434121110.019
proteasomal protein catabolic processGO:001049820.019
regulation of catalytic activityGO:0050790550.019
negative regulation of catabolic processGO:000989530.019
regulation of muscle hypertrophyGO:001474320.019
regulation of cellular amino acid metabolic processGO:000652100.019
cell death in response to oxidative stressGO:003647320.019
regulation of gtpase activityGO:004308720.019
regulation of protein ubiquitinationGO:003139630.019
regulation of peptidyl tyrosine phosphorylationGO:005073010.019
regulation of multicellular organism growthGO:004001440.019
myeloid cell differentiationGO:0030099860.019
anion transportGO:0006820380.019
cellular protein metabolic processGO:00442671290.019
organic substance catabolic processGO:1901575280.019
cellular protein modification processGO:00064641000.019
muscle system processGO:0003012200.019
lipid catabolic processGO:001604240.019
secondary metabolic processGO:001974830.019
regulation of transporter activityGO:003240920.019
positive regulation of nucleotide catabolic processGO:003081310.019
positive regulation of gtpase activityGO:004354710.018
taxisGO:00423301090.018
response to alkaloidGO:004327920.018
response to carbohydrateGO:000974330.018
negative regulation of cell deathGO:0060548600.018
cell morphogenesis involved in differentiationGO:00009041950.017
response to hexoseGO:000974630.017
cellular response to xenobiotic stimulusGO:0071466350.017
organic acid metabolic processGO:0006082310.017
hemopoiesisGO:00300971830.017
protein localization to plasma membraneGO:007265910.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.017
vasculature developmentGO:00019442780.017
negative regulation of endopeptidase activityGO:0010951100.017
photoreceptor cell differentiationGO:0046530550.017
meiotic nuclear divisionGO:000712640.017
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.017
peptide transportGO:001583310.017
protein import into nucleusGO:000660630.017
stem cell differentiationGO:00488631170.017
regulation of wound healingGO:006104120.017
response to vitaminGO:003327330.017
neurotransmitter secretionGO:000726920.017
cell morphogenesis involved in neuron differentiationGO:00486671630.017
regulation of synaptic transmission glycinergicGO:006009210.017
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.016
heart contractionGO:0060047710.016
determination of bilateral symmetryGO:00098552040.016
cellular component biogenesisGO:00440851780.016
germ line stem cell maintenanceGO:003071820.016
response to lipidGO:0033993600.016
regulation of cellular ketone metabolic processGO:001056570.016
negative regulation of protein kinase activityGO:000646940.016
stem cell maintenanceGO:001982740.016
oxidative demethylationGO:007098910.016
neuron projection developmentGO:00311751800.016
cellular response to stressGO:0033554620.016
apoptotic process involved in developmentGO:190274220.016
alcohol biosynthetic processGO:004616520.016
negative regulation of biosynthetic processGO:0009890550.016
positive regulation of apoptotic signaling pathwayGO:200123510.016
negative regulation of intracellular transportGO:003238730.016
superoxide metabolic processGO:000680120.016
negative regulation of signal transductionGO:0009968940.016
negative regulation of apoptotic signaling pathwayGO:2001234100.016
response to oxygen radicalGO:000030520.016
regulation of cell developmentGO:00602841000.016
developmental growthGO:00485891660.015
g1 s transition of mitotic cell cycleGO:000008210.015
muscle cell differentiationGO:00426921390.015
neuronal action potentialGO:0019228180.015
multi organism processGO:00517041340.015
regulation of blood pressureGO:000821710.015
intracellular receptor signaling pathwayGO:0030522300.015
membrane invaginationGO:001032410.015
regulation of rho protein signal transductionGO:003502320.015
regulation of muscle contractionGO:000693730.015
camera type eye photoreceptor cell differentiationGO:0060219190.015
atp catabolic processGO:000620040.015
muscle hypertrophyGO:001489620.015
multicellular organismal signalingGO:0035637220.015
macromolecular complex subunit organizationGO:0043933740.015
membrane repolarizationGO:008600920.015
purine nucleoside monophosphate catabolic processGO:000912840.015
cell cycle g1 s phase transitionGO:004484310.015
regulation of response to stressGO:0080134360.015
axon guidanceGO:0007411860.015
positive regulation of cellular amino acid metabolic processGO:004576400.014
macromolecule localizationGO:0033036540.014
establishment of protein localization to organelleGO:007259440.014
response to woundingGO:00096111160.014
purine ribonucleoside monophosphate catabolic processGO:000916940.014
mitotic recombinationGO:000631220.014
regulation of transmembrane transporter activityGO:002289820.014
embryonic heart tube developmentGO:00350501330.014
tube morphogenesisGO:00352393490.014
positive regulation of cellular amine metabolic processGO:003324000.014
regulation of protein import into nucleusGO:004230620.014
positive regulation of map kinase activityGO:004340630.014
chemical homeostasisGO:0048878490.014
negative regulation of gene expressionGO:0010629650.014
regulation of protein metabolic processGO:0051246560.014
reactive oxygen species metabolic processGO:007259360.014
ear developmentGO:00435831270.014
anterior posterior pattern specificationGO:00099521520.014
regulation of lipid transportGO:003236840.014
developmental programmed cell deathGO:001062340.014
response to organic cyclic compoundGO:0014070510.014
synaptic growth at neuromuscular junctionGO:005112420.014
pigmentationGO:0043473850.013
positive regulation of immune effector processGO:000269930.013
positive regulation of secretionGO:005104710.013
lateral line developmentGO:0048882660.013
negative regulation of cellular catabolic processGO:003133030.013
protein homooligomerizationGO:005126030.013
protein importGO:001703830.013
cellular response to oxygen levelsGO:007145310.013
neuroblast proliferationGO:000740520.013
single organism nuclear importGO:190259330.013
positive regulation of stress activated mapk cascadeGO:003287430.013
regulation of localizationGO:00328791040.013
compound eye developmentGO:004874920.013
response to oxygen containing compoundGO:1901700550.013
dna metabolic processGO:0006259270.013
cellular response to extracellular stimulusGO:003166820.013
negative regulation of hormone secretionGO:004688820.013
negative regulation of protein maturationGO:1903318100.013
cellular response to reactive oxygen speciesGO:003461420.013
regenerationGO:0031099910.013
female sex differentiationGO:004666040.013
regulation of nervous system developmentGO:0051960900.013
negative regulation of cell communicationGO:0010648960.013
endosomal transportGO:001619720.013
cellular response to starvationGO:000926710.013
alpha amino acid metabolic processGO:190160530.013
organic substance transportGO:0071702580.013
regulation of protein complex assemblyGO:004325430.012
autophagyGO:000691440.012
small molecule catabolic processGO:004428230.012
positive regulation of cell communicationGO:0010647560.012
cellular macromolecule localizationGO:0070727210.012
regulation of cell activationGO:005086510.012
posterior lateral line developmentGO:0048916380.012
production of molecular mediator of immune responseGO:000244020.012
regulation of proteolysisGO:0030162240.012
negative regulation of cell differentiationGO:0045596460.012
gliogenesisGO:0042063450.012
striated muscle cell differentiationGO:00511461290.012
regulation of dendrite developmentGO:005077330.012
calcium ion transport into cytosolGO:006040230.012
positive regulation of rna biosynthetic processGO:1902680570.012
cranial nerve developmentGO:0021545420.012
multicellular organismal metabolic processGO:004423620.012
glial cell developmentGO:0021782200.012
response to radiationGO:0009314510.012
nucleoside monophosphate catabolic processGO:000912540.012
organic anion transportGO:0015711150.012
regulation of dna metabolic processGO:0051052110.012
neuron projection guidanceGO:0097485860.012
antimicrobial humoral responseGO:001973020.012
microtubule organizing center organizationGO:003102310.012
sensory system developmentGO:0048880760.012
development of primary female sexual characteristicsGO:004654540.012
striated muscle cell developmentGO:00550021080.012
l amino acid transportGO:001580710.012
cellular response to nutrient levelsGO:003166920.012
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.012
muscle fiber developmentGO:0048747520.012
apoptotic signaling pathwayGO:0097190230.012
centrosome organizationGO:005129710.012
heart loopingGO:0001947940.011
dorsal ventral pattern formationGO:00099531250.011
synaptic transmissionGO:0007268350.011
neutral amino acid transportGO:001580420.011
xenobiotic metabolic processGO:000680540.011
cell substrate adhesionGO:003158940.011
fertilizationGO:000956630.011
cellular protein localizationGO:0034613200.011
cellular response to radiationGO:007147840.011
negative regulation of cytoplasmic transportGO:190365020.011
cytokinesisGO:000091030.011
nerve developmentGO:0021675450.011
retina layer formationGO:0010842240.011
regulation of cell shapeGO:000836010.011
regulation of intracellular signal transductionGO:1902531570.011
single organism behaviorGO:0044708240.011
intrinsic apoptotic signaling pathwayGO:0097193200.011
synaptic vesicle localizationGO:009747910.011
peripheral nervous system developmentGO:0007422550.011
apoptotic process involved in morphogenesisGO:006056120.011
ras protein signal transductionGO:000726570.011
developmental cell growthGO:0048588520.011
skeletal muscle tissue developmentGO:0007519670.011
epithelial tube morphogenesisGO:00605621480.011
nitric oxide metabolic processGO:004620920.011
positive regulation of cellular component biogenesisGO:004408930.011
cellular transition metal ion homeostasisGO:004691630.011
positive regulation of cellular protein metabolic processGO:0032270220.011
single organism membrane fusionGO:004480120.011
regulation of calcium ion transportGO:005192420.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.011
meiotic cell cycle processGO:190304630.011
growthGO:00400071740.011
regulation of epithelial cell proliferationGO:005067830.011
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217620.011
protein processingGO:0016485120.011
muscle cell developmentGO:00550011150.011
carbohydrate homeostasisGO:003350010.011

hsp70 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.065
sensory system diseaseDOID:005015500.012
nervous system diseaseDOID:86300.012
eye diseaseDOID:561400.012
eye and adnexa diseaseDOID:149200.012
disease of cellular proliferationDOID:1456600.012
organ system cancerDOID:005068600.011
cancerDOID:16200.011