Danio rerio

0 known processes

spopla

speckle-type POZ protein-like a

(Aliases: wu:fi71d08,zgc:101524,spopl)

spopla biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.070
agingGO:000756820.049
regulation of multicellular organism growthGO:004001440.045
multicellular organism growthGO:003526440.044
maintenance of locationGO:005123540.041
nucleic acid metabolic processGO:00903042440.041
cellular macromolecule metabolic processGO:00442603910.038
Human
nitrogen compound metabolic processGO:00068073190.037
cellular nitrogen compound metabolic processGO:00346412900.037
organic cyclic compound metabolic processGO:19013603010.036
establishment of protein localization to organelleGO:007259440.036
heterocycle metabolic processGO:00464832900.035
positive regulation of cell cycleGO:004578730.033
cellular aromatic compound metabolic processGO:00067252950.033
positive regulation of cellular component biogenesisGO:004408930.033
stem cell maintenanceGO:001982740.033
rna metabolic processGO:00160702190.032
positive regulation of transportGO:005105020.031
amine metabolic processGO:000930820.030
nucleocytoplasmic transportGO:000691340.030
nucleobase containing compound metabolic processGO:00061392740.030
gene expressionGO:00104672520.029
phagocytosisGO:000690930.029
signal transductionGO:00071654550.029
mitochondrion organizationGO:000700540.029
regulation of macromolecule metabolic processGO:00602553170.029
Human
meiotic nuclear divisionGO:000712640.029
nuclear transportGO:005116940.029
response to stressGO:00069502630.029
cognitionGO:005089010.028
response to chemicalGO:00422213200.028
autophagyGO:000691440.028
organic substance biosynthetic processGO:19015762890.027
regulation of biosynthetic processGO:00098892500.027
cellular protein catabolic processGO:004425740.027
Human
heterocycle biosynthetic processGO:00181302150.027
cytokinesisGO:000091030.026
cellular macromolecule biosynthetic processGO:00346452240.026
regulation of cytokine productionGO:000181730.026
cellular response to external stimulusGO:007149620.026
cellular biosynthetic processGO:00442492860.026
cellular nitrogen compound biosynthetic processGO:00442712180.026
protein localization to nucleusGO:003450430.026
regulation of establishment of protein localizationGO:007020140.026
atp catabolic processGO:000620040.025
nucleic acid templated transcriptionGO:00976591810.025
macromolecule biosynthetic processGO:00090592270.025
cellular ketone metabolic processGO:0042180110.025
ribonucleoside monophosphate catabolic processGO:000915840.025
regulation of gene expressionGO:00104682650.025
modification dependent protein catabolic processGO:001994130.025
Human
proteasomal protein catabolic processGO:001049820.025
Human
cellular amine metabolic processGO:004410620.025
nucleoside monophosphate catabolic processGO:000912540.024
regulation of protein transportGO:005122330.024
regulation of nitrogen compound metabolic processGO:00511712510.024
negative regulation of protein phosphorylationGO:000193340.024
ubiquitin dependent protein catabolic processGO:000651130.024
Human
regulation of cellular amino acid metabolic processGO:000652100.024
cell surface receptor signaling pathwayGO:00071663250.024
regulation of cellular amine metabolic processGO:003323800.024
proteolysis involved in cellular protein catabolic processGO:005160330.024
Human
regulation of nucleobase containing compound metabolic processGO:00192192500.024
negative regulation of biological processGO:00485193040.024
Human
lipid storageGO:001991510.024
positive regulation of catabolic processGO:000989640.024
modification dependent macromolecule catabolic processGO:004363230.023
Human
regulation of autophagyGO:001050630.023
regulation of rna metabolic processGO:00512522240.023
regulation of primary metabolic processGO:00800903110.023
Human
regulation of protein complex assemblyGO:004325430.023
cellular response to nutrient levelsGO:003166920.023
positive regulation of cellular catabolic processGO:003133130.023
neuron differentiationGO:00301823530.023
transcription dna templatedGO:00063511810.023
purine ribonucleoside monophosphate catabolic processGO:000916940.023
extrinsic apoptotic signaling pathwayGO:009719130.023
regulation of cell activationGO:005086510.023
regulation of cellular macromolecule biosynthetic processGO:20001122220.023
biosynthetic processGO:00090582940.023
regulation of cellular biosynthetic processGO:00313262450.023
aromatic compound biosynthetic processGO:00194382170.023
nuclear importGO:005117030.023
regulation of mrna processingGO:005068430.022
response to uvGO:000941130.022
purine nucleoside monophosphate catabolic processGO:000912840.022
protein targeting to nucleusGO:004474430.022
regulation of protein catabolic processGO:004217610.022
regulation of metabolic processGO:00192223590.022
Human
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.022
Human
cellular response to extracellular stimulusGO:003166820.022
regulation of rna biosynthetic processGO:20011412130.022
negative regulation of cellular processGO:00485232830.022
Human
single organism metabolic processGO:00447102170.022
rna biosynthetic processGO:00327741810.022
regulation of cellular metabolic processGO:00313233200.022
Human
leukocyte proliferationGO:007066110.022
organic cyclic compound biosynthetic processGO:19013622230.021
regulation of macromolecule biosynthetic processGO:00105562250.021
protein import into nucleusGO:000660630.021
single organism nuclear importGO:190259330.021
regulation of metal ion transportGO:001095940.021
morphogenesis of an epitheliumGO:00020093330.021
regulation of cytoplasmic transportGO:190364940.021
positive regulation of protein complex assemblyGO:003133420.021
response to drugGO:004249330.021
regulation of response to stimulusGO:00485832690.021
rna localizationGO:000640340.021
protein acetylationGO:000647320.021
nucleobase containing compound biosynthetic processGO:00346542050.021
female sex differentiationGO:004666040.020
alternative mrna splicing via spliceosomeGO:000038010.020
i kappab kinase nf kappab signalingGO:000724940.020
cell substrate adhesionGO:003158940.020
regulation of nucleic acid templated transcriptionGO:19035062130.020
protein importGO:001703830.020
regulation of cell shapeGO:000836010.020
endosomal transportGO:001619720.020
generation of neuronsGO:00486993850.020
mononuclear cell proliferationGO:003294310.019
regulation of nucleocytoplasmic transportGO:004682220.019
adult behaviorGO:003053420.019
regulation of dna replicationGO:000627530.019
synaptic growth at neuromuscular junctionGO:005112420.019
regulation of signalingGO:00230512350.019
positive regulation of cell activationGO:005086710.019
regulation of biological qualityGO:00650082630.019
gtp catabolic processGO:000618420.019
cellular carbohydrate metabolic processGO:004426240.019
regulation of developmental processGO:00507932470.019
double strand break repairGO:000630230.019
meiotic cell cycle processGO:190304630.019
cytoskeleton dependent cytokinesisGO:006164030.019
regulation of synapse organizationGO:005080730.019
regulation of cellular ketone metabolic processGO:001056570.019
sensory organ developmentGO:00074233930.019
positive regulation of cytoskeleton organizationGO:005149530.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.019
cellular component movementGO:00069283350.018
embryo development ending in birth or egg hatchingGO:00097922710.018
regulation of transcription dna templatedGO:00063552130.018
stem cell proliferationGO:007208940.018
establishment of localizationGO:00512342440.018
cell part morphogenesisGO:00329902460.018
single organism membrane fusionGO:004480120.018
tissue remodelingGO:004877140.018
cell morphogenesisGO:00009022890.018
negative regulation of kinase activityGO:003367340.018
negative regulation of protein kinase activityGO:000646940.018
guanosine containing compound metabolic processGO:190106840.018
eye developmentGO:00016542770.018
oxoacid metabolic processGO:0043436310.018
organelle organizationGO:00069962270.018
gtp metabolic processGO:004603940.018
regulation of stem cell proliferationGO:007209120.018
cell projection morphogenesisGO:00488582440.018
cellular component disassemblyGO:002241110.018
response to external stimulusGO:00096052640.018
regulation of peptidyl tyrosine phosphorylationGO:005073010.018
regulation of nucleotide catabolic processGO:003081120.018
peptidyl lysine acetylationGO:001839420.018
regulation of protein modification by small protein conjugation or removalGO:190332030.018
Human
tube morphogenesisGO:00352393490.018
internal protein amino acid acetylationGO:000647520.018
cellular amino acid metabolic processGO:000652070.018
cellular response to chemical stimulusGO:00708871570.018
erk1 and erk2 cascadeGO:007037140.018
membrane fusionGO:006102520.018
neuron developmentGO:00486662620.018
immune system processGO:00023762410.018
protein metabolic processGO:00195381830.018
Human
cellular response to starvationGO:000926710.017
negative regulation of protein transportGO:005122430.017
regulation of cell communicationGO:00106462320.017
regulation of protein ubiquitinationGO:003139630.017
Human
regulation of neural precursor cell proliferationGO:200017730.017
regulation of erk1 and erk2 cascadeGO:007037240.017
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.017
regulation of protein localization to nucleusGO:190018020.017
regulation of bindingGO:005109830.017
carboxylic acid metabolic processGO:0019752220.017
internal peptidyl lysine acetylationGO:001839320.017
regulation of i kappab kinase nf kappab signalingGO:004312240.017
digestive system developmentGO:00551232890.017
locomotor rhythmGO:004547530.017
positive regulation of immune effector processGO:000269930.017
guanosine containing compound catabolic processGO:190106920.017
organic acid metabolic processGO:0006082310.017
regulation of reproductive processGO:200024140.017
sequestering of calcium ionGO:005120830.017
small molecule metabolic processGO:0044281770.017
peptidyl serine phosphorylationGO:001810510.017
microtubule organizing center organizationGO:003102310.017
regulation of nucleoside metabolic processGO:000911820.017
cellular component morphogenesisGO:00329893360.016
neuron neuron synaptic transmissionGO:000727010.016
organelle fusionGO:004828430.016
primary neural tube formationGO:001402010.016
embryonic organ developmentGO:00485683810.016
locomotionGO:00400113130.016
regulation of intracellular protein transportGO:003315730.016
centrosome organizationGO:005129710.016
regulation of multicellular organismal processGO:00512392770.016
negative regulation of catabolic processGO:000989530.016
regulation of protein targetingGO:190353320.016
secondary metabolic processGO:001974830.016
positive regulation of erk1 and erk2 cascadeGO:007037420.016
negative regulation of sequestering of calcium ionGO:005128340.016
response to organic substanceGO:00100331530.016
lymphocyte proliferationGO:004665110.016
cell projection organizationGO:00300302840.016
regulation of extrinsic apoptotic signaling pathwayGO:200123630.016
regulation of inflammatory responseGO:005072720.016
positive regulation of cellular amine metabolic processGO:003324000.016
chordate embryonic developmentGO:00430092710.016
central nervous system developmentGO:00074173870.016
positive regulation of cytokine productionGO:000181920.016
exocytosisGO:000688710.016
regulation of meiotic cell cycleGO:005144510.016
somatic muscle developmentGO:000752540.016
regulation of mrna splicing via spliceosomeGO:004802430.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
head developmentGO:00603223030.016
protein dephosphorylationGO:000647030.016
single organism localizationGO:19025782250.016
regulation of signal transductionGO:00099662250.016
negative regulation of mapk cascadeGO:004340940.016
tube closureGO:006060610.016
peptidyl serine modificationGO:001820920.016
establishment of protein localization to plasma membraneGO:009000210.016
nuclear exportGO:005116810.016
protein secretionGO:000930610.015
protein acylationGO:004354330.015
system processGO:00030081850.015
organonitrogen compound metabolic processGO:1901564740.015
phagocytosis engulfmentGO:000691110.015
positive regulation of lymphocyte mediated immunityGO:000270810.015
positive regulation of i kappab kinase nf kappab signalingGO:004312330.015
regulation of protein import into nucleusGO:004230620.015
cellular response to oxygen levelsGO:007145310.015
protein complex disassemblyGO:004324110.015
regulation of sequestering of calcium ionGO:005128240.015
regulation of purine nucleotide catabolic processGO:003312120.015
b cell activationGO:004211320.015
cell migrationGO:00164772370.015
positive regulation of biological processGO:00485182530.015
cell matrix adhesionGO:000716040.015
cellular component assemblyGO:00226071700.015
g1 s transition of mitotic cell cycleGO:000008210.015
cellular response to molecule of bacterial originGO:007121930.015
vasculature developmentGO:00019442780.015
localization of cellGO:00516742440.015
regulation of alternative mrna splicing via spliceosomeGO:000038110.015
negative regulation of nuclear divisionGO:005178430.015
sequestering of metal ionGO:005123830.015
protein localization to plasma membraneGO:007265910.015
macromolecular complex disassemblyGO:003298410.015
cellular protein metabolic processGO:00442671290.015
Human
dna templated transcription elongationGO:000635430.015
macroautophagyGO:001623610.015
cell morphogenesis involved in differentiationGO:00009041950.015
lipid catabolic processGO:001604240.015
positive regulation of dna metabolic processGO:005105410.015
adherens junction organizationGO:003433240.015
transportGO:00068102200.015
cellular response to decreased oxygen levelsGO:003629410.015
cell cycle g1 s phase transitionGO:004484310.015
blood vessel developmentGO:00015682460.015
double strand break repair via homologous recombinationGO:000072410.014
regulation of synapse assemblyGO:005196330.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
single organism organelle organizationGO:19025891990.014
germ line stem cell maintenanceGO:003071820.014
lipid homeostasisGO:005508830.014
response to nutrientGO:000758430.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.014
digestive tract developmentGO:00485652650.014
blood vessel morphogenesisGO:00485142160.014
protein polyubiquitinationGO:000020940.014
regulation of synaptic plasticityGO:004816710.014
positive regulation of translationGO:004572710.014
development of primary female sexual characteristicsGO:004654540.014
cellular amide metabolic processGO:004360340.014
cell morphogenesis involved in neuron differentiationGO:00486671630.014
positive regulation of secretionGO:005104710.014
synaptic vesicle transportGO:004848910.014
homeostatic processGO:00425921420.014
neuroblast proliferationGO:000740520.014
chemosensory behaviorGO:000763510.014
golgi vesicle transportGO:004819330.014
spermatid developmentGO:000728620.014
regulation of multicellular organismal developmentGO:20000262230.014
cellular component biogenesisGO:00440851780.014
membrane invaginationGO:001032410.014
lateral inhibitionGO:004633110.014
organic acid catabolic processGO:001605430.014
cellular response to organic substanceGO:00713101050.014
negative regulation of cytoplasmic transportGO:190365020.014
symbiosis encompassing mutualism through parasitismGO:004440340.014
positive regulation of cell adhesionGO:004578510.014
stem cell divisionGO:001714510.014
negative regulation of cellular catabolic processGO:003133030.014
macromolecule modificationGO:00434121110.014
Human
heart developmentGO:00075073130.014
signal transduction in absence of ligandGO:003803410.014
single organism transportGO:00447652060.014
positive regulation of secretion by cellGO:190353210.014
sensory organ morphogenesisGO:00905962000.014
release of sequestered calcium ion into cytosolGO:005120930.013
spermatid differentiationGO:004851520.013
cell substrate junction assemblyGO:000704420.013
regulation of dendrite developmentGO:005077330.013
neurotransmitter transportGO:000683620.013
rna modificationGO:000945120.013
recombinational repairGO:000072510.013
regulation of cellular protein catabolic processGO:190336210.013
positive regulation of nucleotide catabolic processGO:003081310.013
single fertilizationGO:000733830.013
regulation of dna templated transcription in response to stressGO:004362000.013
nucleic acid transportGO:005065720.013
negative regulation of cytokine productionGO:000181810.013
mitotic dna integrity checkpointGO:004477440.013
compound eye developmentGO:004874920.013
glucose homeostasisGO:004259310.013
intracellular signal transductionGO:0035556850.013
transcription from rna polymerase ii promoterGO:0006366800.013
carbohydrate homeostasisGO:003350010.013
mitochondrial transportGO:000683920.013
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
cell motilityGO:00488702440.013
regulation of gtpase activityGO:004308720.013
fertilizationGO:000956630.013
actin polymerization or depolymerizationGO:000815420.013
protein heterooligomerizationGO:005129110.013
regulation of epithelial cell proliferationGO:005067830.013
negative regulation of protein import into nucleusGO:004230820.013
regulation of organelle assemblyGO:190211540.013
regulation of production of molecular mediator of immune responseGO:000270010.013
establishment of synaptic vesicle localizationGO:009748010.013
immune system developmentGO:00025201910.013
alcohol biosynthetic processGO:004616520.013
cellular response to lipopolysaccharideGO:007122230.013
regulation of gtp catabolic processGO:003312420.013
cellular response to hypoxiaGO:007145610.013
cellular response to radiationGO:007147840.013
peptide transportGO:001583310.013
response to carbohydrateGO:000974330.013
carboxylic acid catabolic processGO:004639530.012
positive regulation of nucleoside metabolic processGO:004597910.012
digestive tract morphogenesisGO:00485462310.012
regulation of response to biotic stimulusGO:000283120.012
regionalizationGO:00030022740.012
hemopoiesisGO:00300971830.012
viral processGO:001603210.012
negative regulation of protein serine threonine kinase activityGO:007190120.012
antimicrobial humoral responseGO:001973020.012
regulation of jak stat cascadeGO:004642530.012
cytosolic calcium ion transportGO:006040130.012
positive regulation of purine nucleotide catabolic processGO:003312310.012
rna 3 end processingGO:003112320.012
response to monosaccharideGO:003428430.012
regulation of cell substrate adhesionGO:001081010.012
positive regulation of chromatin modificationGO:190331010.012
regulation of ion transmembrane transporter activityGO:003241220.012
regulation of transporter activityGO:003240920.012
developmental growthGO:00485891660.012
positive regulation of cellular processGO:00485222010.012
actin filament polymerizationGO:003004120.012
growthGO:00400071740.012
angiogenesisGO:00015251580.012
small molecule catabolic processGO:004428230.012
negative regulation of defense responseGO:003134820.012
gastrulationGO:00073692080.012
mitotic dna damage checkpointGO:004477340.012
mitotic cytokinesisGO:000028130.012
toll like receptor signaling pathwayGO:000222440.012
female gonad developmentGO:000858540.012
calcium ion transport into cytosolGO:006040230.012
protein homooligomerizationGO:005126030.012
interspecies interaction between organismsGO:004441940.012
response to hexoseGO:000974630.012
cortical cytoskeleton organizationGO:003086510.012
positive regulation of chromosome organizationGO:200125210.012
response to abiotic stimulusGO:00096281220.012
regulation of response to nutrient levelsGO:003210710.012
protein polymerizationGO:005125840.012
response to hydrogen peroxideGO:004254230.012
post embryonic organ developmentGO:004856940.012
cellular response to biotic stimulusGO:007121630.012
neuron projection morphogenesisGO:00488121610.012
phosphatidylinositol mediated signalingGO:004801520.012
wnt signaling pathwayGO:0016055800.012
response to topologically incorrect proteinGO:003596620.012
negative regulation of intracellular protein transportGO:009031730.012
negative regulation of metabolic processGO:0009892860.012
Human
peptidyl threonine phosphorylationGO:001810710.012
cellular response to light stimulusGO:007148240.011
meiotic chromosome segregationGO:004513230.011
cellular protein modification processGO:00064641000.011
Human
negative regulation of nucleocytoplasmic transportGO:004682320.011
regulation of transcription from rna polymerase ii promoterGO:00063571140.011
regulation of calcium ion transportGO:005192420.011
synaptic vesicle localizationGO:009747910.011
negative regulation of intracellular transportGO:003238730.011
sleepGO:003043110.011
regulation of circadian rhythmGO:004275240.011
production of molecular mediator of immune responseGO:000244020.011
negative regulation of secretionGO:005104820.011
regulation of protein complex disassemblyGO:004324410.011
nucleobase containing compound transportGO:001593120.011
positive regulation of jnk cascadeGO:004633030.011
regulation of stem cell differentiationGO:200073640.011
regulation of cell differentiationGO:00455951420.011
intracellular mrna localizationGO:000829810.011
specification of symmetryGO:00097992040.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.011
vacuolar transportGO:000703420.011
regulation of blood pressureGO:000821710.011
multi organism cellular processGO:004476420.011
regulation of cellular carbohydrate metabolic processGO:001067540.011
establishment of rna localizationGO:005123630.011
positive regulation of gtp catabolic processGO:003312610.011
cell deathGO:00082191210.011
response to glucoseGO:000974930.011
regulation of response to extracellular stimulusGO:003210410.011
response to corticosteroidGO:003196010.011
mitotic cell cycle embryonicGO:004544820.011
multi organism processGO:00517041340.011
camera type eye developmentGO:00430102220.011
cellular lipid catabolic processGO:004424230.011
positive regulation of protein polymerizationGO:003227320.011
regulation of chromosome segregationGO:005198310.011
brain developmentGO:00074202930.010
centrosome duplicationGO:005129810.010
regulation of dendrite morphogenesisGO:004881430.010
retina development in camera type eyeGO:00600411460.010
positive regulation of map kinase activityGO:004340630.010
regulation of protein polymerizationGO:003227120.010
positive regulation of gtpase activityGO:004354710.010
liver developmentGO:0001889960.010
positive regulation of stress activated mapk cascadeGO:003287430.010
developmental programmed cell deathGO:001062340.010
response to alkaloidGO:004327920.010
somatic stem cell maintenanceGO:003501910.010
positive regulation of histone modificationGO:003105810.010
cellular transition metal ion homeostasisGO:004691630.010
embryonic organ morphogenesisGO:00485622740.010
centrosome cycleGO:000709810.010
rna transportGO:005065820.010
negative regulation of response to stimulusGO:00485851040.010
cellular respirationGO:004533330.010
mitotic g2 m transition checkpointGO:004481830.010
deathGO:00162651210.010
regulation of neurotransmitter transportGO:005158810.010
cytokinetic processGO:003250620.010
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.010
positive regulation of myeloid cell differentiationGO:004563920.010
positive regulation of canonical wnt signaling pathwayGO:009026340.010
cilium morphogenesisGO:0060271850.010
lipid oxidationGO:003444010.010
regulation of carbohydrate metabolic processGO:000610940.010
organism emergence from protective structureGO:007168440.010
inositol lipid mediated signalingGO:004801720.010
determination of left right symmetryGO:00073681790.010
negative regulation of macromolecule metabolic processGO:0010605760.010
Human
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.010
negative regulation of signal transductionGO:0009968940.010
regulation of dna templated transcription elongationGO:003278430.010
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.010

spopla disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.049
nervous system diseaseDOID:86300.023
disease of cellular proliferationDOID:1456600.020
musculoskeletal system diseaseDOID:1700.018
cancerDOID:16200.018
organ system cancerDOID:005068600.018
disease of metabolismDOID:001466700.017
muscle tissue diseaseDOID:6600.013
muscular diseaseDOID:008000000.013
inherited metabolic disorderDOID:65500.012
immune system diseaseDOID:291400.012
myopathyDOID:42300.011