Danio rerio

0 known processes

fgd4

FYVE, RhoGEF and PH domain containing 4

(Aliases: fgd4a,si:ch211-194i18.1,si:dkey-57m7.1)

fgd4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
biosynthetic processGO:00090582940.092
cellular component morphogenesisGO:00329893360.087
Worm
regulation of biological qualityGO:00650082630.077
Worm
larval developmentGO:000216420.075
positive regulation of transportGO:005105020.073
negative regulation of biological processGO:00485193040.070
regulation of multicellular organismal processGO:00512392770.069
cell morphogenesisGO:00009022890.069
Worm
cellular biosynthetic processGO:00442492860.068
cellular response to external stimulusGO:007149620.067
regulation of biosynthetic processGO:00098892500.060
organic substance biosynthetic processGO:19015762890.060
response to stressGO:00069502630.058
immune system processGO:00023762410.057
agingGO:000756820.057
guanosine containing compound metabolic processGO:190106840.057
cellular aromatic compound metabolic processGO:00067252950.054
cellular response to starvationGO:000926710.052
localization of cellGO:00516742440.051
regulation of metabolic processGO:00192223590.051
positive regulation of cellular component biogenesisGO:004408930.051
small molecule metabolic processGO:0044281770.050
nitrogen compound metabolic processGO:00068073190.050
gtp metabolic processGO:004603940.049
positive regulation of biological processGO:00485182530.047
maternal determination of anterior posterior axis embryoGO:000835840.047
regulation of cytokine productionGO:000181730.047
cell migrationGO:00164772370.046
cellular nitrogen compound metabolic processGO:00346412900.046
response to monosaccharideGO:003428430.045
positive regulation of cellular catabolic processGO:003133130.045
cellular component assemblyGO:00226071700.045
adult behaviorGO:003053420.044
gtp catabolic processGO:000618420.044
regulation of cellular metabolic processGO:00313233200.043
single organism metabolic processGO:00447102170.043
regionalizationGO:00030022740.043
gene expressionGO:00104672520.042
cell projection organizationGO:00300302840.042
generation of neuronsGO:00486993850.042
cellular component movementGO:00069283350.041
nucleobase containing compound metabolic processGO:00061392740.041
cell motilityGO:00488702440.041
carboxylic acid metabolic processGO:0019752220.040
maintenance of locationGO:005123540.040
cell morphogenesis involved in differentiationGO:00009041950.040
response to drugGO:004249330.040
signal transductionGO:00071654550.039
cellular response to nutrient levelsGO:003166920.039
central nervous system developmentGO:00074173870.039
organonitrogen compound metabolic processGO:1901564740.039
organic cyclic compound metabolic processGO:19013603010.039
regulation of primary metabolic processGO:00800903110.038
sleepGO:003043110.038
cellular response to extracellular stimulusGO:003166820.037
cellular component biogenesisGO:00440851780.036
amine metabolic processGO:000930820.036
regulation of establishment of protein localizationGO:007020140.036
negative regulation of cellular processGO:00485232830.036
regulation of protein transportGO:005122330.035
regulation of cellular biosynthetic processGO:00313262450.035
guanosine containing compound catabolic processGO:190106920.035
lipid storageGO:001991510.035
protein secretionGO:000930610.035
response to external stimulusGO:00096052640.035
organic acid metabolic processGO:0006082310.034
response to chemicalGO:00422213200.034
regulation of multicellular organismal developmentGO:20000262230.034
regulation of multicellular organism growthGO:004001440.034
positive regulation of catabolic processGO:000989640.033
regulation of cell projection assemblyGO:006049140.033
single organism localizationGO:19025782250.033
macromolecule biosynthetic processGO:00090592270.033
homeostatic processGO:00425921420.033
regulation of wound healingGO:006104120.033
cellular ketone metabolic processGO:0042180110.032
regulation of cell activationGO:005086510.032
pole plasm assemblyGO:000731540.032
positive regulation of nucleoside metabolic processGO:004597910.032
cellular nitrogen compound biosynthetic processGO:00442712180.032
membrane fusionGO:006102520.031
actin polymerization or depolymerizationGO:000815420.031
connective tissue developmentGO:0061448990.031
regulation of nitrogen compound metabolic processGO:00511712510.030
regulation of gene expressionGO:00104682650.030
multicellular organism growthGO:003526440.029
cellular response to chemical stimulusGO:00708871570.029
establishment of protein localization to organelleGO:007259440.029
regulation of protein complex assemblyGO:004325430.029
cellular macromolecule metabolic processGO:00442603910.028
positive regulation of ras protein signal transductionGO:004657910.028
heterocycle metabolic processGO:00464832900.028
regulation of macromolecule metabolic processGO:00602553170.028
leukocyte proliferationGO:007066110.028
regulation of macromolecule biosynthetic processGO:00105562250.028
oocyte anterior posterior axis specificationGO:000731440.028
neuron differentiationGO:00301823530.028
response to nutrientGO:000758430.028
sensory organ developmentGO:00074233930.028
regulation of filopodium assemblyGO:005148920.028
response to hexoseGO:000974630.028
response to biotic stimulusGO:0009607970.027
positive regulation of cytokine productionGO:000181920.027
nucleic acid templated transcriptionGO:00976591810.027
establishment of localizationGO:00512342440.027
phagocytosisGO:000690930.027
positive regulation of cell cycleGO:004578730.027
aromatic compound biosynthetic processGO:00194382170.027
rna metabolic processGO:00160702190.027
ubiquitin dependent protein catabolic processGO:000651130.027
nucleocytoplasmic transportGO:000691340.026
oxoacid metabolic processGO:0043436310.026
organic cyclic compound biosynthetic processGO:19013622230.026
regulation of nucleic acid templated transcriptionGO:19035062130.026
positive regulation of cellular processGO:00485222010.026
regulation of developmental processGO:00507932470.026
immune system developmentGO:00025201910.026
symbiosis encompassing mutualism through parasitismGO:004440340.026
nucleic acid metabolic processGO:00903042440.026
regulation of cell shapeGO:000836010.026
brain developmentGO:00074202930.025
regulation of signalingGO:00230512350.025
protein targeting to nucleusGO:004474430.025
single fertilizationGO:000733830.025
regulation of intracellular protein transportGO:003315730.024
protein import into nucleusGO:000660630.024
regulation of protein modification by small protein conjugation or removalGO:190332030.024
wound healingGO:0042060900.024
protein metabolic processGO:00195381830.024
proteolysis involved in cellular protein catabolic processGO:005160330.024
estrogen metabolic processGO:000821020.024
proteasomal protein catabolic processGO:001049820.024
ectodermal placode developmentGO:0071696370.023
system processGO:00030081850.023
stem cell proliferationGO:007208940.023
intracellular mrna localizationGO:000829810.023
positive regulation of cell activationGO:005086710.023
neuron neuron synaptic transmissionGO:000727010.023
regulation of protein polymerizationGO:003227120.022
response to glucoseGO:000974930.022
membrane invaginationGO:001032410.022
positive regulation of purine nucleotide catabolic processGO:003312310.022
regulation of rna biosynthetic processGO:20011412130.022
positive regulation of cytoskeleton organizationGO:005149530.022
secondary metabolic processGO:001974830.022
single organism transportGO:00447652060.022
meiotic nuclear divisionGO:000712640.022
phagocytosis engulfmentGO:000691110.022
neuron projection morphogenesisGO:00488121610.022
regulation of transcription dna templatedGO:00063552130.022
protein importGO:001703830.022
cytoplasm organizationGO:000702840.022
regulation of nucleobase containing compound metabolic processGO:00192192500.021
regulation of apoptotic processGO:0042981980.021
transcription dna templatedGO:00063511810.021
nucleobase containing compound biosynthetic processGO:00346542050.021
positive regulation of protein complex assemblyGO:003133420.021
modification dependent macromolecule catabolic processGO:004363230.021
neuron developmentGO:00486662620.021
regulation of muscle contractionGO:000693730.021
positive regulation of gtp catabolic processGO:003312610.021
protein localization to plasma membraneGO:007265910.021
cellular protein catabolic processGO:004425740.021
single organism nuclear importGO:190259330.020
cellular macromolecule biosynthetic processGO:00346452240.020
regulation of cellular ketone metabolic processGO:001056570.020
regulation of protein targetingGO:190353320.020
embryonic organ developmentGO:00485683810.020
regulation of response to stimulusGO:00485832690.020
neuron projection developmentGO:00311751800.020
regulation of purine nucleotide catabolic processGO:003312120.020
negative regulation of cytokine productionGO:000181810.020
transportGO:00068102200.020
regulation of transcription from rna polymerase iii promoterGO:000635910.020
stem cell differentiationGO:00488631170.020
regulation of signal transductionGO:00099662250.020
melanin metabolic processGO:000658220.020
regulation of nucleotide catabolic processGO:003081120.020
negative regulation of cell communicationGO:0010648960.020
ameboidal type cell migrationGO:00016671430.020
skeletal system developmentGO:00015011810.019
morphogenesis of an epitheliumGO:00020093330.019
regulation of nucleoside metabolic processGO:000911820.019
cellular response to xenobiotic stimulusGO:0071466350.019
glial cell migrationGO:000834730.019
cell part morphogenesisGO:00329902460.019
digestive tract morphogenesisGO:00485462310.019
protein polymerizationGO:005125840.019
regulation of cellular amine metabolic processGO:003323800.019
single organism organelle organizationGO:19025891990.019
heterocycle biosynthetic processGO:00181302150.019
rna biosynthetic processGO:00327741810.019
cellular amine metabolic processGO:004410620.019
cell deathGO:00082191210.019
negative regulation of secretionGO:005104820.019
negative regulation of signalingGO:0023057960.019
regulation of erk1 and erk2 cascadeGO:007037240.019
response to woundingGO:00096111160.019
post embryonic organ developmentGO:004856940.019
regulation of cell deathGO:00109411030.019
negative regulation of secretion by cellGO:190353120.019
cellular response to oxygen levelsGO:007145310.019
regulation of cytoplasmic transportGO:190364940.019
segmentationGO:0035282970.019
cell cycle g1 s phase transitionGO:004484310.019
axon developmentGO:00615641660.019
rna localizationGO:000640340.019
positive regulation of nucleotide catabolic processGO:003081310.018
dorsal ventral pattern formationGO:00099531250.018
hematopoietic or lymphoid organ developmentGO:00485341910.018
modification dependent protein catabolic processGO:001994130.018
locomotionGO:00400113130.018
Worm
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.018
regulation of cell communicationGO:00106462320.018
response to xenobiotic stimulusGO:0009410450.018
multi organism cellular processGO:004476420.018
retina development in camera type eyeGO:00600411460.018
autophagyGO:000691440.018
embryonic skeletal system developmentGO:0048706970.018
startle responseGO:000196440.018
anterior posterior pattern specificationGO:00099521520.018
organelle organizationGO:00069962270.018
regulation of autophagyGO:001050630.018
interspecies interaction between organismsGO:004441940.018
regulation of reproductive processGO:200024140.018
blood vessel developmentGO:00015682460.018
digestive tract developmentGO:00485652650.018
cranial nerve developmentGO:0021545420.018
defense responseGO:0006952470.018
response to carbohydrateGO:000974330.018
positive regulation of cellular amino acid metabolic processGO:004576400.018
developmental programmed cell deathGO:001062340.018
regulation of protein import into nucleusGO:004230620.017
carbohydrate derivative metabolic processGO:1901135610.017
cellular localizationGO:0051641970.017
meiotic chromosome segregationGO:004513230.017
establishment of protein localization to plasma membraneGO:009000210.017
cell morphogenesis involved in neuron differentiationGO:00486671630.017
regulation of protein ubiquitinationGO:003139630.017
lipid homeostasisGO:005508830.017
protein localization to nucleusGO:003450430.017
single organism biosynthetic processGO:0044711710.017
gland developmentGO:00487321430.017
organelle fusionGO:004828430.017
macromolecular complex disassemblyGO:003298410.017
i kappab kinase nf kappab signalingGO:000724940.017
long chain fatty acid metabolic processGO:000167610.017
positive regulation of immune effector processGO:000269930.017
stem cell fate commitmentGO:004886510.017
regulation of cellular component organizationGO:0051128860.017
growthGO:00400071740.017
cytokinesisGO:000091030.017
nuclear transportGO:005116940.017
cellular component disassemblyGO:002241110.016
mitochondrion organizationGO:000700540.016
positive regulation of metabolic processGO:00098931080.016
synaptic growth at neuromuscular junctionGO:005112420.016
regulation of phGO:000688530.016
embryonic skeletal joint morphogenesisGO:006027230.016
mononuclear cell proliferationGO:003294310.016
regulation of circadian sleep wake cycleGO:004274910.016
nerve developmentGO:0021675450.016
xenobiotic metabolic processGO:000680540.016
cell projection morphogenesisGO:00488582440.016
regulation of rna metabolic processGO:00512522240.016
digestive system developmentGO:00551232890.016
negative regulation of cellular catabolic processGO:003133030.016
nuclear importGO:005117030.016
phosphate containing compound metabolic processGO:00067961080.016
fertilizationGO:000956630.016
regenerationGO:0031099910.016
response to other organismGO:0051707970.016
positive regulation of cellular amine metabolic processGO:003324000.016
sodium ion importGO:009736930.016
cellular response to hypoxiaGO:007145610.016
smooth muscle contractionGO:000693920.016
apoptotic processGO:00069151160.016
tissue remodelingGO:004877140.016
lamellipodium assemblyGO:003003210.016
protein polyubiquitinationGO:000020940.016
response to ketoneGO:190165410.016
production of molecular mediator of immune responseGO:000244020.016
axonogenesisGO:00074091520.016
cortical cytoskeleton organizationGO:003086510.015
positive regulation of secretion by cellGO:190353210.015
sensory system developmentGO:0048880760.015
vasculature developmentGO:00019442780.015
deathGO:00162651210.015
regulation of cellular macromolecule biosynthetic processGO:20001122220.015
compound eye developmentGO:004874920.015
regulation of response to extracellular stimulusGO:003210410.015
cellular component assembly involved in morphogenesisGO:00109271070.015
cognitionGO:005089010.015
multi organism processGO:00517041340.015
axon ensheathment in central nervous systemGO:003229120.015
peptide metabolic processGO:000651810.015
positive regulation of erk1 and erk2 cascadeGO:007037420.015
sensory perception of painGO:001923310.015
negative regulation of protein transportGO:005122430.015
programmed cell deathGO:00125011190.015
erk1 and erk2 cascadeGO:007037140.015
protein complex disassemblyGO:004324110.015
phosphorus metabolic processGO:00067931090.015
regulation of nucleocytoplasmic transportGO:004682220.015
blood circulationGO:0008015870.015
regulation of peptidyl tyrosine phosphorylationGO:005073010.015
regulation of circadian rhythmGO:004275240.015
lateral line system developmentGO:0048925760.015
negative regulation of response to stimulusGO:00485851040.015
regulation of fatty acid metabolic processGO:001921710.015
developmental pigmentationGO:0048066480.015
cellular amino acid metabolic processGO:000652070.015
positive regulation of cell adhesionGO:004578510.015
transcription from rna polymerase iii promoterGO:000638310.014
hemopoiesisGO:00300971830.014
negative regulation of apoptotic processGO:0043066550.014
regulation of programmed cell deathGO:00430671010.014
eye developmentGO:00016542770.014
regulation of synapse assemblyGO:005196330.014
regulation of inflammatory responseGO:005072720.014
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.014
sensory organ morphogenesisGO:00905962000.014
regulation of gtpase activityGO:004308720.014
chordate embryonic developmentGO:00430092710.014
response to external biotic stimulusGO:0043207970.014
negative regulation of catabolic processGO:000989530.014
epithelial tube morphogenesisGO:00605621480.014
cartilage developmentGO:0051216960.014
regulation of cellular amino acid metabolic processGO:000652100.014
positive regulation of gtpase activityGO:004354710.014
defense response to fungusGO:005083220.014
cell projection assemblyGO:0030031640.014
embryo development ending in birth or egg hatchingGO:00097922710.014
regulation of protein catabolic processGO:004217610.014
regulation of bindingGO:005109830.014
sympathetic nervous system developmentGO:004848530.013
single organism membrane fusionGO:004480120.013
regulation of gtp catabolic processGO:003312420.013
viral processGO:001603210.013
cell surface receptor signaling pathwayGO:00071663250.013
golgi vesicle transportGO:004819330.013
small molecule catabolic processGO:004428230.013
reactive oxygen species biosynthetic processGO:190340910.013
defense response to other organismGO:0098542330.013
regulation of response to nutrient levelsGO:003210710.013
cellular monovalent inorganic cation homeostasisGO:003000420.013
peptide transportGO:001583310.013
ribonucleoside monophosphate catabolic processGO:000915840.013
gastrulationGO:00073692080.013
skeletal system morphogenesisGO:00487051020.013
leukocyte homeostasisGO:000177620.013
positive regulation of signal transductionGO:0009967560.013
regulation of neurotransmitter transportGO:005158810.013
regulation of cell projection organizationGO:0031344440.013
cellular response to organic substanceGO:00713101050.013
g1 s transition of mitotic cell cycleGO:000008210.013
female gonad developmentGO:000858540.013
regulation of glial cell differentiationGO:004568540.013
meiotic cell cycle processGO:190304630.013
atp catabolic processGO:000620040.013
extrinsic apoptotic signaling pathwayGO:009719130.013
intracellular signal transductionGO:0035556850.013
nucleoside monophosphate catabolic processGO:000912540.013
positive regulation of macromolecule metabolic processGO:0010604930.013
tube morphogenesisGO:00352393490.013
lymphocyte proliferationGO:004665110.013
stem cell maintenanceGO:001982740.013
eye morphogenesisGO:00485921440.013
cytoskeleton dependent cytokinesisGO:006164030.013
regulation of protein complex disassemblyGO:004324410.013
cytoskeleton organizationGO:0007010960.012
nitric oxide metabolic processGO:004620920.012
macromolecule localizationGO:0033036540.012
negative regulation of cell deathGO:0060548600.012
taxisGO:00423301090.012
negative regulation of response to cytokine stimulusGO:006076120.012
ectodermal placode morphogenesisGO:0071697320.012
regulation of cell differentiationGO:00455951420.012
cellular amide metabolic processGO:004360340.012
actin filament polymerizationGO:003004120.012
embryonic organ morphogenesisGO:00485622740.012
positive regulation of i kappab kinase nf kappab signalingGO:004312330.012
regulation of molecular functionGO:0065009700.012
peripheral nervous system developmentGO:0007422550.012
neurological system processGO:0050877620.012
chemical homeostasisGO:0048878490.012
regulation of i kappab kinase nf kappab signalingGO:004312240.012
positive regulation of nitrogen compound metabolic processGO:0051173690.012
endosomal transportGO:001619720.012
head developmentGO:00603223030.012
regulation of blood pressureGO:000821710.012
pigment cell differentiationGO:0050931380.012
response to alkaloidGO:004327920.012
lipid catabolic processGO:001604240.012
regulation of localizationGO:00328791040.012
pectoral fin developmentGO:0033339500.012
phosphatidylinositol 3 kinase signalingGO:001406520.012
response to glucocorticoidGO:005138410.012
regulation of metal ion transportGO:001095940.012
multicellular organismal macromolecule metabolic processGO:004425920.012
positive regulation of cellular metabolic processGO:0031325940.012
ear developmentGO:00435831270.012
cell killingGO:000190620.012
camera type eye developmentGO:00430102220.012
hatching gland developmentGO:004878530.012
protein modification processGO:00362111000.012
response to endogenous stimulusGO:0009719830.012
neuron projection guidanceGO:0097485860.012
negative regulation of signal transductionGO:0009968940.012
establishment of localization in cellGO:0051649770.012
response to organic substanceGO:00100331530.012
phosphorylationGO:0016310690.012
negative regulation of protein serine threonine kinase activityGO:007190120.012
cell substrate adhesionGO:003158940.012
inner ear developmentGO:00488391260.011
kidney developmentGO:0001822920.011
regulation of response to biotic stimulusGO:000283120.011
chemotaxisGO:00069351040.011
chemosensory behaviorGO:000763510.011
angiogenesisGO:00015251580.011
regulation of nervous system developmentGO:0051960900.011
protein complex localizationGO:003150310.011
medulla oblongata developmentGO:002155040.011
response to lipidGO:0033993600.011
heart developmentGO:00075073130.011
positive regulation of response to stimulusGO:0048584800.011
natural killer cell mediated cytotoxicityGO:004226710.011
axis specificationGO:0009798430.011
melanocyte differentiationGO:0030318260.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.011
peptidyl threonine modificationGO:001821010.011
peptidyl serine modificationGO:001820920.011
tissue regenerationGO:0042246740.011
negative regulation of multi organism processGO:004390130.011
mesenchyme developmentGO:00604851270.011
regulation of cell substrate adhesionGO:001081010.011
glycoprotein biosynthetic processGO:0009101210.011
regulation of rho protein signal transductionGO:003502320.011
cell cell recognitionGO:000998810.011
cellular carbohydrate metabolic processGO:004426240.011
regulation of transporter activityGO:003240920.011
developmental maturationGO:0021700340.011
lipid metabolic processGO:0006629520.011
sphingolipid biosynthetic processGO:003014820.011
dorsal motor nucleus of vagus nerve developmentGO:002174440.011
purine ribonucleoside monophosphate catabolic processGO:000916940.011
regulation of protein depolymerizationGO:190187910.011
exocytosisGO:000688710.010
negative regulation of nitrogen compound metabolic processGO:0051172590.010
pigmentationGO:0043473850.010
negative regulation of cytoplasmic transportGO:190365020.010
negative regulation of intracellular transportGO:003238730.010
negative regulation of mapk cascadeGO:004340940.010
cellular protein metabolic processGO:00442671290.010
single organismal cell cell adhesionGO:0016337290.010
protein targeting to membraneGO:000661210.010
macroautophagyGO:001623610.010
positive regulation of wound healingGO:009030310.010
response to bacteriumGO:0009617580.010
positive regulation of small gtpase mediated signal transductionGO:005105710.010
developmental growthGO:00485891660.010
organic substance transportGO:0071702580.010
specification of axis polarityGO:006500140.010
hepaticobiliary system developmentGO:0061008980.010
response to transition metal nanoparticleGO:1990267280.010
renal system developmentGO:0072001940.010
cell migration involved in gastrulationGO:0042074790.010

fgd4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
Human
organ system cancerDOID:005068600.020
disease of cellular proliferationDOID:1456600.020
cancerDOID:16200.020
musculoskeletal system diseaseDOID:1700.014
immune system diseaseDOID:291400.013
nervous system diseaseDOID:86300.011
Human
connective tissue diseaseDOID:6500.010