Danio rerio

0 known processes

pdlim4

PDZ and LIM domain 4

pdlim4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell substrate adhesionGO:003158940.917
Fly
neuron projection morphogenesisGO:00488121610.889
regulation of cell substrate adhesionGO:001081010.883
Fly
regulation of cell adhesionGO:0030155150.876
Fly
regulation of cell matrix adhesionGO:000195210.830
Fly
cellular component morphogenesisGO:00329893360.793
Fly
neuron projection developmentGO:00311751800.752
heart developmentGO:00075073130.673
Zebrafish
regulation of multicellular organismal processGO:00512392770.644
eye developmentGO:00016542770.574
cell matrix adhesionGO:000716040.522
Fly
cell part morphogenesisGO:00329902460.507
regulation of synapse assemblyGO:005196330.505
regulation of anatomical structure morphogenesisGO:00226031300.501
sensory organ developmentGO:00074233930.490
regulation of axon extensionGO:0030516240.472
nucleobase containing compound biosynthetic processGO:00346542050.466
generation of neuronsGO:00486993850.431
response to woundingGO:00096111160.423
morphogenesis of an epitheliumGO:00020093330.394
striated muscle cell developmentGO:00550021080.382
Fly
response to external stimulusGO:00096052640.377
somitogenesisGO:0001756870.361
Zebrafish
axonogenesisGO:00074091520.359
cell projection morphogenesisGO:00488582440.354
neuron differentiationGO:00301823530.347
positive regulation of biological processGO:00485182530.347
compound eye developmentGO:004874920.339
muscle structure developmentGO:00610611960.335
Fly
eye morphogenesisGO:00485921440.329
response to chemicalGO:00422213200.328
biosynthetic processGO:00090582940.325
cell projection organizationGO:00300302840.323
modification dependent macromolecule catabolic processGO:004363230.322
regulation of developmental processGO:00507932470.318
vasculature developmentGO:00019442780.311
segmentationGO:0035282970.304
Zebrafish
agingGO:000756820.300
regulation of macromolecule metabolic processGO:00602553170.290
developmental growthGO:00485891660.277
regulation of cell morphogenesisGO:0022604420.268
neuron projection extensionGO:1990138450.266
myofibril assemblyGO:0030239480.263
Fly
blood vessel developmentGO:00015682460.261
cell morphogenesisGO:00009022890.260
cellular component assemblyGO:00226071700.251
Fly
cellular macromolecule metabolic processGO:00442603910.247
cell morphogenesis involved in neuron differentiationGO:00486671630.226
anterior posterior pattern specificationGO:00099521520.210
Zebrafish
small molecule metabolic processGO:0044281770.208
somite developmentGO:0061053960.208
Zebrafish
response to stressGO:00069502630.206
regulation of cellular component organizationGO:0051128860.200
neuron developmentGO:00486662620.195
regulation of nervous system developmentGO:0051960900.189
cellular component assembly involved in morphogenesisGO:00109271070.187
Fly
heterocycle biosynthetic processGO:00181302150.185
regulation of multicellular organismal developmentGO:20000262230.179
blood vessel morphogenesisGO:00485142160.177
response to copper ionGO:0046688130.174
axon extensionGO:0048675450.168
response to transition metal nanoparticleGO:1990267280.168
cellular biosynthetic processGO:00442492860.167
single organism organelle organizationGO:19025891990.164
Fly
cell adhesionGO:0007155400.164
Fly
regulation of extent of cell growthGO:0061387290.158
stem cell differentiationGO:00488631170.157
regulation of cell developmentGO:00602841000.152
organic substance biosynthetic processGO:19015762890.143
actin filament bundle organizationGO:006157260.136
ubiquitin dependent protein catabolic processGO:000651130.134
organic cyclic compound biosynthetic processGO:19013622230.132
regulation of cytoskeleton organizationGO:0051493110.131
embryonic skeletal system morphogenesisGO:0048704930.131
regulation of protein modification by small protein conjugation or removalGO:190332030.128
amine metabolic processGO:000930820.128
cell growthGO:0016049570.126
locomotionGO:00400113130.126
chordate embryonic developmentGO:00430092710.124
Zebrafish
regulation of primary metabolic processGO:00800903110.121
modification dependent protein catabolic processGO:001994130.119
positive regulation of developmental processGO:0051094500.118
extracellular structure organizationGO:0043062270.117
regulation of rna biosynthetic processGO:20011412130.116
regionalizationGO:00030022740.113
Zebrafish
synaptic growth at neuromuscular junctionGO:005112420.113
positive regulation of multicellular organismal processGO:0051240520.112
axon guidanceGO:0007411860.109
regulation of gene expressionGO:00104682650.107
hindbrain developmentGO:0030902910.106
axon developmentGO:00615641660.105
aromatic compound biosynthetic processGO:00194382170.105
embryo development ending in birth or egg hatchingGO:00097922710.104
Zebrafish
cell morphogenesis involved in differentiationGO:00009041950.104
positive regulation of cellular processGO:00485222010.103
camera type eye morphogenesisGO:00485931080.102
negative regulation of protein kinase activityGO:000646940.101
taxisGO:00423301090.101
negative regulation of axon extension involved in axon guidanceGO:004884310.097
embryonic heart tube morphogenesisGO:00031431080.097
rna biosynthetic processGO:00327741810.096
sensory organ morphogenesisGO:00905962000.094
regulation of biological qualityGO:00650082630.093
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.090
positive regulation of neurogenesisGO:0050769240.090
growthGO:00400071740.089
oxoacid metabolic processGO:0043436310.088
response to metal ionGO:0010038340.088
epithelial tube morphogenesisGO:00605621480.085
regulation of cell communicationGO:00106462320.083
tube morphogenesisGO:00352393490.082
regulation of rna metabolic processGO:00512522240.080
connective tissue developmentGO:0061448990.080
positive regulation of cell differentiationGO:0045597300.079
angiogenesisGO:00015251580.078
organelle organizationGO:00069962270.078
Fly
regulation of cellular metabolic processGO:00313233200.077
neuron projection guidanceGO:0097485860.076
regulation of cell projection organizationGO:0031344440.076
regulation of cell shapeGO:000836010.076
response to inorganic substanceGO:0010035380.076
response to other organismGO:0051707970.074
skeletal muscle organ developmentGO:0060538780.074
gene expressionGO:00104672520.073
cell migrationGO:00164772370.073
regulation of macromolecule biosynthetic processGO:00105562250.072
positive regulation of nucleobase containing compound metabolic processGO:0045935690.072
regulation of neuron differentiationGO:0045664560.072
regulation of cell morphogenesis involved in differentiationGO:0010769380.072
biological adhesionGO:0022610400.071
Fly
extracellular matrix assemblyGO:008502910.071
camera type eye developmentGO:00430102220.071
localization of cellGO:00516742440.070
skeletal system morphogenesisGO:00487051020.070
cytoskeleton organizationGO:0007010960.069
Fly
positive regulation of cellular amino acid metabolic processGO:004576400.068
mesenchyme developmentGO:00604851270.067
morphogenesis of embryonic epitheliumGO:0016331300.067
cellular protein catabolic processGO:004425740.067
gland developmentGO:00487321430.066
negative regulation of cellular processGO:00485232830.065
embryonic eye morphogenesisGO:0048048300.065
nucleobase containing compound metabolic processGO:00061392740.064
establishment of localizationGO:00512342440.063
cellular component biogenesisGO:00440851780.063
Fly
actomyosin structure organizationGO:0031032530.061
Fly
positive regulation of cellular component biogenesisGO:004408930.061
regulation of neuron projection developmentGO:0010975400.061
embryonic cranial skeleton morphogenesisGO:0048701900.060
proteolysis involved in cellular protein catabolic processGO:005160330.060
embryonic organ morphogenesisGO:00485622740.060
regulation of cytoplasmic transportGO:190364940.060
proteasomal protein catabolic processGO:001049820.059
heart loopingGO:0001947940.058
response to drugGO:004249330.058
regulation of cell sizeGO:0008361290.058
mesenchymal cell differentiationGO:0048762870.057
embryonic heart tube developmentGO:00350501330.056
muscle cell differentiationGO:00426921390.056
Fly
cellular component movementGO:00069283350.055
regulation of response to stimulusGO:00485832690.055
cartilage developmentGO:0051216960.054
signal transductionGO:00071654550.053
regulation of transcription from rna polymerase ii promoterGO:00063571140.052
regulation of cell differentiationGO:00455951420.052
regulation of synapse organizationGO:005080730.052
positive regulation of cell developmentGO:0010720250.052
retina morphogenesis in camera type eyeGO:0060042790.051
regulation of cellular amino acid metabolic processGO:000652100.050
cilium organizationGO:0044782710.050
cell deathGO:00082191210.049
cellular amino acid metabolic processGO:000652070.049
cellular amine metabolic processGO:004410620.049
cell fate commitmentGO:0045165990.049
stem cell divisionGO:001714510.049
response to biotic stimulusGO:0009607970.048
developmental cell growthGO:0048588520.048
positive regulation of cell projection organizationGO:003134690.047
establishment of localization in cellGO:0051649770.047
cell motilityGO:00488702440.045
organic cyclic compound metabolic processGO:19013603010.045
cell death in response to oxidative stressGO:003647320.045
visual behaviorGO:0007632100.045
organelle assemblyGO:00709251100.045
Fly
gastrulationGO:00073692080.044
thymus developmentGO:0048538100.044
cell projection assemblyGO:0030031640.043
mesenchymal cell developmentGO:0014031780.043
single organism biosynthetic processGO:0044711710.043
heterocycle metabolic processGO:00464832900.042
nitrogen compound metabolic processGO:00068073190.042
response to organic substanceGO:00100331530.042
cellular aromatic compound metabolic processGO:00067252950.042
muscle organ developmentGO:00075171010.042
regulation of axonogenesisGO:0050770320.041
negative regulation of macromolecule metabolic processGO:0010605760.041
oocyte maturationGO:000155640.041
regulation of protein ubiquitinationGO:003139630.040
regulation of transcription dna templatedGO:00063552130.040
head developmentGO:00603223030.040
rna modificationGO:000945120.040
organic acid metabolic processGO:0006082310.039
glial cell migrationGO:000834730.039
cell substrate junction assemblyGO:000704420.039
negative regulation of nervous system developmentGO:0051961220.039
cardiac atrium developmentGO:000323040.038
collagen fibril organizationGO:003019910.038
chemotaxisGO:00069351040.038
adult behaviorGO:003053420.038
regulation of cellular amine metabolic processGO:003323800.038
regulation of neurogenesisGO:0050767870.038
negative regulation of catalytic activityGO:0043086210.038
nucleic acid metabolic processGO:00903042440.038
response to external biotic stimulusGO:0043207970.037
digestive tract morphogenesisGO:00485462310.036
positive regulation of axon extensionGO:004577350.036
lipid metabolic processGO:0006629520.036
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.036
skeletal system developmentGO:00015011810.035
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:004315470.035
rna metabolic processGO:00160702190.035
negative regulation of cell developmentGO:0010721260.035
regulation of anatomical structure sizeGO:0090066330.034
olfactory bulb developmentGO:002177240.034
cellular nitrogen compound biosynthetic processGO:00442712180.034
regulation of developmental growthGO:0048638380.033
embryonic viscerocranium morphogenesisGO:0048703520.033
cilium assemblyGO:0042384580.033
regulation of cellular protein metabolic processGO:0032268520.033
retina layer formationGO:0010842240.032
cell surface receptor signaling pathwayGO:00071663250.032
single organism metabolic processGO:00447102170.031
positive regulation of transportGO:005105020.031
regulation of cytokine productionGO:000181730.031
cerebellum developmentGO:0021549170.031
deathGO:00162651210.031
heart morphogenesisGO:00030071560.031
nucleic acid templated transcriptionGO:00976591810.031
macromolecule biosynthetic processGO:00090592270.031
regulation of metabolic processGO:00192223590.031
regulation of growthGO:0040008420.031
protein metabolic processGO:00195381830.031
regulation of organ morphogenesisGO:2000027350.030
single organism transportGO:00447652060.030
extracellular matrix organizationGO:0030198270.030
positive regulation of rna metabolic processGO:0051254590.030
organonitrogen compound biosynthetic processGO:1901566470.030
cellular macromolecule biosynthetic processGO:00346452240.029
negative regulation of protein phosphorylationGO:000193340.029
muscle cell developmentGO:00550011150.029
Fly
actin cytoskeleton organizationGO:0030036630.029
Fly
ribosomal small subunit biogenesisGO:004227420.029
negative regulation of kinase activityGO:003367340.029
positive regulation of neuron differentiationGO:0045666120.029
regulation of signal transductionGO:00099662250.028
regulation of cell deathGO:00109411030.028
organonitrogen compound metabolic processGO:1901564740.028
intracellular receptor signaling pathwayGO:0030522300.028
negative regulation of gene expressionGO:0010629650.027
axonal defasciculationGO:000741420.026
positive regulation of cell growthGO:003030750.026
cellular ketone metabolic processGO:0042180110.026
cardioblast differentiationGO:001000290.026
cardiac atrium morphogenesisGO:000320920.025
negative regulation of biological processGO:00485193040.025
astrocyte differentiationGO:004870810.025
endocrine system developmentGO:0035270650.025
regulation of nucleic acid templated transcriptionGO:19035062130.025
heart valve formationGO:000318840.025
transportGO:00068102200.024
cellular response to hypoxiaGO:007145610.024
regulation of skeletal muscle tissue developmentGO:004864140.024
dendrite guidanceGO:007098300.024
single organism localizationGO:19025782250.024
convergent extensionGO:00600261180.024
regulation of behaviorGO:0050795240.024
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.024
regulation of nucleobase containing compound metabolic processGO:00192192500.024
regulation of cell migrationGO:0030334400.024
outflow tract morphogenesisGO:000315110.024
behaviorGO:0007610740.024
water homeostasisGO:003010440.023
positive regulation of neuron projection developmentGO:001097690.023
positive regulation of cellular amine metabolic processGO:003324000.023
regulation of cellular macromolecule biosynthetic processGO:20001122220.023
regulation of multicellular organism growthGO:004001440.023
positive regulation of nucleic acid templated transcriptionGO:1903508570.023
establishment of protein localization to organelleGO:007259440.023
cellular response to stressGO:0033554620.023
positive regulation of axonogenesisGO:005077260.022
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.022
glial cell differentiationGO:0010001420.022
macromolecule modificationGO:00434121110.022
gliogenesisGO:0042063450.022
olfactory lobe developmentGO:002198840.022
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.022
mitotic dna integrity checkpointGO:004477440.022
atrioventricular valve formationGO:000319030.022
response to corticosteroidGO:003196010.021
axon ensheathment in central nervous systemGO:003229120.021
transcription from rna polymerase ii promoterGO:0006366800.021
blood vessel endothelial cell migrationGO:0043534180.021
multicellular organism growthGO:003526440.021
negative regulation of growthGO:0045926100.021
synapse assemblyGO:000741690.021
embryonic digestive tract developmentGO:004856640.021
midbrain developmentGO:0030901280.020
negative regulation of cytokine productionGO:000181810.020
regulation of cellular biosynthetic processGO:00313262450.020
regulation of peptidyl tyrosine phosphorylationGO:005073010.020
striated muscle cell differentiationGO:00511461290.020
Fly
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.020
embryonic retina morphogenesis in camera type eyeGO:0060059220.020
positive regulation of synapse assemblyGO:005196510.020
developmental maturationGO:0021700340.019
brain developmentGO:00074202930.019
determination of heart left right asymmetryGO:00613711170.019
positive regulation of cytoskeleton organizationGO:005149530.019
golgi vesicle transportGO:004819330.019
carboxylic acid metabolic processGO:0019752220.019
regulation of neuron migrationGO:200122220.019
developmental growth involved in morphogenesisGO:0060560860.019
respiratory system developmentGO:006054150.019
mesenchymal cell proliferationGO:001046310.019
transcription dna templatedGO:00063511810.019
cellular protein metabolic processGO:00442671290.018
hepatocyte proliferationGO:007257420.018
central nervous system myelinationGO:002201020.018
phosphorus metabolic processGO:00067931090.018
macromolecular complex subunit organizationGO:0043933740.018
tissue homeostasisGO:0001894250.018
regulation of actin cytoskeleton organizationGO:003295680.018
larval developmentGO:000216420.018
branching morphogenesis of a nerveGO:004875540.018
nephron tubule morphogenesisGO:007207810.018
positive regulation of signalingGO:0023056560.018
central nervous system developmentGO:00074173870.018
response to nicotineGO:003509420.018
negative regulation of cell migrationGO:0030336170.017
cellular response to chemical stimulusGO:00708871570.017
muscle fiber developmentGO:0048747520.017
regulation of cellular ketone metabolic processGO:001056570.017
stem cell proliferationGO:007208940.017
protein importGO:001703830.017
meiotic nuclear divisionGO:000712640.017
intracellular signal transductionGO:0035556850.017
embryonic organ developmentGO:00485683810.017
regenerationGO:0031099910.017
tissue migrationGO:0090130370.017
negative regulation of protein metabolic processGO:0051248160.017
forebrain developmentGO:0030900960.016
regulation of cellular component sizeGO:0032535300.016
regulation of mrna processingGO:005068430.016
positive regulation of apoptotic signaling pathwayGO:200123510.016
nuclear importGO:005117030.016
positive regulation of muscle tissue developmentGO:190186310.016
enzyme linked receptor protein signaling pathwayGO:00071671060.016
regulation of cellular component biogenesisGO:0044087120.016
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.016
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathwayGO:002200210.016
response to uvGO:000941130.016
multi organism processGO:00517041340.015
digestive tract developmentGO:00485652650.015
positive regulation of muscle organ developmentGO:004863610.015
transmembrane transportGO:00550851200.015
positive regulation of cellular biosynthetic processGO:0031328680.015
peptidyl serine phosphorylationGO:001810510.015
determination of bilateral symmetryGO:00098552040.015
wound healingGO:0042060900.015
regulation of biosynthetic processGO:00098892500.015
g2 dna damage checkpointGO:003157230.015
regulation of phGO:000688530.015
regulation of collateral sprouting in absence of injuryGO:004869640.015
regulation of stem cell differentiationGO:200073640.015
homeostasis of number of cells within a tissueGO:004887340.015
atrial ventricular junction remodelingGO:000329420.014
regulation of mrna splicing via spliceosomeGO:004802430.014
protein modification processGO:00362111000.014
negative regulation of transcription dna templatedGO:0045892450.014
axon regenerationGO:0031103140.014
positive regulation of rna biosynthetic processGO:1902680570.014
axis elongation involved in somitogenesisGO:009024520.014
neural crest cell differentiationGO:0014033720.014
melanin metabolic processGO:000658220.014
programmed cell deathGO:00125011190.014
cellular protein modification processGO:00064641000.014
embryonic camera type eye morphogenesisGO:0048596190.013
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.013
tissue regenerationGO:0042246740.013
regulation of localizationGO:00328791040.013
proteolysisGO:0006508380.013
homeostatic processGO:00425921420.013
regulation of protein catabolic processGO:004217610.013
regulation of axon regenerationGO:004867970.013
regulation of skeletal muscle fiber developmentGO:004874220.013
catechol containing compound biosynthetic processGO:000971320.013
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.013
regulation of heart growthGO:006042020.013
response to ketoneGO:190165410.013
regulation of nitrogen compound metabolic processGO:00511712510.013
regulation of programmed cell deathGO:00430671010.013
cardiac cell fate commitmentGO:006091110.013
response to vitaminGO:003327330.013
negative regulation of endopeptidase activityGO:0010951100.012
endocrine pancreas developmentGO:0031018270.012
organophosphate metabolic processGO:0019637370.012
negative regulation of immune responseGO:005077720.012
appendage morphogenesisGO:0035107560.012
vasculogenesisGO:0001570410.012
positive regulation of macromolecule biosynthetic processGO:0010557590.012
stress fiber assemblyGO:004314950.012
regulation of apoptotic processGO:0042981980.012
response to unfolded proteinGO:000698620.012
er nucleus signaling pathwayGO:000698420.012
negative regulation of anterior neural cell fate commitment of the neural plateGO:002200110.012
phagocytosisGO:000690930.012
positive regulation of cell morphogenesis involved in differentiationGO:001077060.012
cell adhesion mediated by integrinGO:003362710.012
regulation of signalingGO:00230512350.012
regulation of extrinsic apoptotic signaling pathwayGO:200123630.012
cell cycle g1 s phase transitionGO:004484310.011
regulation of protein metabolic processGO:0051246560.011
cellular response to radiationGO:007147840.011
extrinsic apoptotic signaling pathwayGO:009719130.011
cellular response to external stimulusGO:007149620.011
nerve developmentGO:0021675450.011
regulation of filopodium assemblyGO:005148920.011
negative regulation of apoptotic processGO:0043066550.011
g1 s transition of mitotic cell cycleGO:000008210.011
negative regulation of cysteine type endopeptidase activityGO:200011780.011
regulation of intracellular protein transportGO:003315730.011
negative regulation of macromolecule biosynthetic processGO:0010558480.011
regulation of growth rateGO:004000910.011
regulation of production of molecular mediator of immune responseGO:000270010.011
carbon dioxide transportGO:001567030.011
female sex differentiationGO:004666040.011
negative regulation of locomotionGO:0040013180.011
specification of symmetryGO:00097992040.011
nucleocytoplasmic transportGO:000691340.011
response to yeastGO:0001878230.011
apoptotic processGO:00069151160.011
negative regulation of developmental processGO:0051093650.011
specification of axis polarityGO:006500140.011
endodermal digestive tract morphogenesisGO:006103120.011
motor neuron axon guidanceGO:0008045230.011
hormone secretionGO:004687920.010
commissural neuron axon guidanceGO:007167930.010
regulation of cell motilityGO:2000145460.010
synapse organizationGO:0050808210.010
regulation of dendrite developmentGO:005077330.010
maintenance of locationGO:005123540.010
hormone transportGO:000991420.010
cellular response to extracellular stimulusGO:003166820.010
positive regulation of response to stimulusGO:0048584800.010
membrane invaginationGO:001032410.010
establishment of cell polarityGO:0030010180.010
ribosome assemblyGO:004225510.010
positive regulation of metabolic processGO:00098931080.010
peptide metabolic processGO:000651810.010
axonal fasciculationGO:0007413110.010

pdlim4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.039
Human
nervous system diseaseDOID:86300.031
cancerDOID:16200.015
colon carcinomaDOID:152000.015
organ system cancerDOID:005068600.015
colorectal cancerDOID:925600.015
intestinal cancerDOID:1015500.015
gastrointestinal system cancerDOID:311900.015
colon cancerDOID:21900.015
large intestine cancerDOID:567200.015
disease of cellular proliferationDOID:1456600.015
eye and adnexa diseaseDOID:149200.011
sensory system diseaseDOID:005015500.011
eye diseaseDOID:561400.011