Danio rerio

37 known processes

frmd8

FERM domain containing 8

frmd8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
tube morphogenesisGO:00352393490.137
digestive tract morphogenesisGO:00485462310.124
morphogenesis of an epitheliumGO:00020093330.109
larval developmentGO:000216420.104
digestive tract developmentGO:00485652650.097
digestive system developmentGO:00551232890.095
gastrulationGO:00073692080.081
embryonic organ morphogenesisGO:00485622740.076
embryonic organ developmentGO:00485683810.075
agingGO:000756820.073
maintenance of locationGO:005123540.066
sensory organ developmentGO:00074233930.061
locomotionGO:00400113130.058
localization of cellGO:00516742440.057
regulation of cell communicationGO:00106462320.057
multicellular organism growthGO:003526440.056
cellular component movementGO:00069283350.055
ameboidal type cell migrationGO:00016671430.055
regulation of multicellular organism growthGO:004001440.053
stem cell maintenanceGO:001982740.052
heart developmentGO:00075073130.050
neuron projection developmentGO:00311751800.050
cell part morphogenesisGO:00329902460.050
regulation of signal transductionGO:00099662250.049
skeletal system developmentGO:00015011810.047
cellular protein catabolic processGO:004425740.047
nitrogen compound metabolic processGO:00068073190.047
cell motilityGO:00488702440.046
positive regulation of biological processGO:00485182530.045
determination of left right symmetryGO:00073681790.045
regulation of signalingGO:00230512350.045
regionalizationGO:00030022740.044
neuron differentiationGO:00301823530.043
regulation of macromolecule metabolic processGO:00602553170.043
positive regulation of cellular component biogenesisGO:004408930.042
positive regulation of transportGO:005105020.042
signal transductionGO:00071654550.042
heart loopingGO:0001947940.042
ear developmentGO:00435831270.041
cytokinesisGO:000091030.041
convergent extension involved in gastrulationGO:0060027710.041
organonitrogen compound metabolic processGO:1901564740.041
regulation of synapse assemblyGO:005196330.040
cell migrationGO:00164772370.040
generation of neuronsGO:00486993850.040
cell projection morphogenesisGO:00488582440.040
head developmentGO:00603223030.040
camera type eye developmentGO:00430102220.039
regulation of metabolic processGO:00192223590.039
small molecule metabolic processGO:0044281770.039
blood vessel developmentGO:00015682460.039
single organism metabolic processGO:00447102170.039
regulation of synapse organizationGO:005080730.039
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.038
sensory organ morphogenesisGO:00905962000.038
regulation of biological qualityGO:00650082630.038
determination of bilateral symmetryGO:00098552040.038
negative regulation of catabolic processGO:000989530.038
single organism organelle organizationGO:19025891990.038
cognitionGO:005089010.038
response to chemicalGO:00422213200.038
axon developmentGO:00615641660.038
regulation of peptidyl tyrosine phosphorylationGO:005073010.037
cell morphogenesisGO:00009022890.037
regulation of protein catabolic processGO:004217610.036
cell morphogenesis involved in differentiationGO:00009041950.036
response to stressGO:00069502630.036
synaptic growth at neuromuscular junctionGO:005112420.036
convergent extensionGO:00600261180.036
cell projection organizationGO:00300302840.035
gene expressionGO:00104672520.035
epithelial tube morphogenesisGO:00605621480.035
specification of symmetryGO:00097992040.035
negative regulation of cellular processGO:00485232830.035
embryonic heart tube morphogenesisGO:00031431080.034
lipid storageGO:001991510.034
phosphate containing compound metabolic processGO:00067961080.034
proteolysis involved in cellular protein catabolic processGO:005160330.034
single organism transportGO:00447652060.034
cellular component morphogenesisGO:00329893360.034
modification dependent protein catabolic processGO:001994130.033
exocytosisGO:000688710.033
organic cyclic compound metabolic processGO:19013603010.033
proteasomal protein catabolic processGO:001049820.033
ubiquitin dependent protein catabolic processGO:000651130.033
ear morphogenesisGO:0042471640.032
protein localization to nucleusGO:003450430.032
central nervous system developmentGO:00074173870.032
regulation of cellular amino acid metabolic processGO:000652100.032
cellular amine metabolic processGO:004410620.032
regulation of gene expressionGO:00104682650.032
adult behaviorGO:003053420.031
cell migration involved in gastrulationGO:0042074790.031
brain developmentGO:00074202930.031
heterocycle metabolic processGO:00464832900.031
protein targeting to nucleusGO:004474430.031
nucleobase containing compound metabolic processGO:00061392740.031
modification dependent macromolecule catabolic processGO:004363230.031
regulation of developmental processGO:00507932470.031
positive regulation of erk1 and erk2 cascadeGO:007037420.030
nuclear transportGO:005116940.030
regulation of epithelial cell proliferationGO:005067830.030
peptidyl serine phosphorylationGO:001810510.030
regulation of cellular amine metabolic processGO:003323800.030
chemotaxisGO:00069351040.029
cellular component biogenesisGO:00440851780.029
regulation of synaptic growth at neuromuscular junctionGO:000858210.029
neuron developmentGO:00486662620.029
organelle organizationGO:00069962270.029
establishment of protein localization to organelleGO:007259440.029
transportGO:00068102200.029
regulation of establishment of protein localizationGO:007020140.029
cell surface receptor signaling pathwayGO:00071663250.029
neuron projection morphogenesisGO:00488121610.028
amine metabolic processGO:000930820.028
positive regulation of cell cycleGO:004578730.028
stem cell proliferationGO:007208940.028
nuclear importGO:005117030.028
cellular response to extracellular stimulusGO:003166820.028
negative regulation of mapk cascadeGO:004340940.028
negative regulation of biological processGO:00485193040.028
negative regulation of protein phosphorylationGO:000193340.028
regulation of protein transportGO:005122330.028
nucleoside monophosphate catabolic processGO:000912540.028
determination of heart left right asymmetryGO:00613711170.028
single organism localizationGO:19025782250.028
cellular component disassemblyGO:002241110.028
protein complex disassemblyGO:004324110.028
cellular nitrogen compound metabolic processGO:00346412900.027
vasculature developmentGO:00019442780.027
regulation of multicellular organismal developmentGO:20000262230.027
chordate embryonic developmentGO:00430092710.027
protein metabolic processGO:00195381830.027
regulation of cytoplasmic transportGO:190364940.027
mitochondrion organizationGO:000700540.027
inner ear developmentGO:00488391260.027
positive regulation of catabolic processGO:000989640.027
macromolecular complex disassemblyGO:003298410.027
single fertilizationGO:000733830.026
nucleocytoplasmic transportGO:000691340.026
protein import into nucleusGO:000660630.026
response to carbohydrateGO:000974330.026
neurotransmitter transportGO:000683620.026
organic acid metabolic processGO:0006082310.026
dorsal ventral pattern formationGO:00099531250.026
eye developmentGO:00016542770.026
nucleic acid metabolic processGO:00903042440.026
hormone transportGO:000991420.026
inner ear morphogenesisGO:0042472630.026
regulation of erk1 and erk2 cascadeGO:007037240.026
regulation of intracellular protein transportGO:003315730.025
aromatic compound biosynthetic processGO:00194382170.025
anterior posterior pattern specificationGO:00099521520.025
regulation of cellular metabolic processGO:00313233200.025
response to hexoseGO:000974630.025
embryonic skeletal system developmentGO:0048706970.025
cellular macromolecule metabolic processGO:00442603910.025
positive regulation of cellular amine metabolic processGO:003324000.024
regulation of ion transmembrane transporter activityGO:003241220.024
positive regulation of exocytosisGO:004592110.024
regulation of biosynthetic processGO:00098892500.024
developmental growthGO:00485891660.024
cellular localizationGO:0051641970.024
embryonic limb morphogenesisGO:003032620.024
axonogenesisGO:00074091520.024
regulation of cellular ketone metabolic processGO:001056570.023
oocyte anterior posterior axis specificationGO:000731440.023
heterocycle biosynthetic processGO:00181302150.023
appendage developmentGO:0048736800.023
extrinsic apoptotic signaling pathwayGO:009719130.023
embryo development ending in birth or egg hatchingGO:00097922710.023
meiotic nuclear divisionGO:000712640.023
purine ribonucleoside monophosphate catabolic processGO:000916940.023
erk1 and erk2 cascadeGO:007037140.023
cellular response to external stimulusGO:007149620.023
microtubule based processGO:0007017600.023
nuclear migrationGO:000709730.023
guanosine containing compound catabolic processGO:190106920.023
maternal determination of anterior posterior axis embryoGO:000835840.023
lateral line system developmentGO:0048925760.023
guanosine containing compound metabolic processGO:190106840.022
establishment of localizationGO:00512342440.022
negative regulation of cellular catabolic processGO:003133030.022
protein importGO:001703830.022
regulation of bindingGO:005109830.022
atp catabolic processGO:000620040.022
intracellular signal transductionGO:0035556850.022
cellular aromatic compound metabolic processGO:00067252950.022
peptidyl threonine phosphorylationGO:001810710.022
protein dephosphorylationGO:000647030.022
phagocytosisGO:000690930.022
endosomal transportGO:001619720.022
gtp catabolic processGO:000618420.022
regulation of protein localization to nucleusGO:190018020.022
golgi vesicle transportGO:004819330.022
single organism nuclear importGO:190259330.021
cellular response to nutrient levelsGO:003166920.021
regulation of extrinsic apoptotic signaling pathwayGO:200123630.021
cilium morphogenesisGO:0060271850.021
somite developmentGO:0061053960.021
negative regulation of map kinase activityGO:004340720.021
neuromast developmentGO:0048884460.021
gtp metabolic processGO:004603940.021
positive regulation of cellular amino acid metabolic processGO:004576400.021
response to drugGO:004249330.021
regulation of metal ion transportGO:001095940.021
cellular protein modification processGO:00064641000.021
positive regulation of synapse assemblyGO:005196510.021
regulation of stem cell differentiationGO:200073640.021
phagocytosis engulfmentGO:000691110.021
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.021
cellular nitrogen compound biosynthetic processGO:00442712180.021
negative regulation of protein kinase activityGO:000646940.021
positive regulation of secretion by cellGO:190353210.021
organic substance biosynthetic processGO:19015762890.020
cellular ketone metabolic processGO:0042180110.020
peptidyl serine modificationGO:001820920.020
regulation of protein targetingGO:190353320.020
organelle localizationGO:0051640490.020
embryonic skeletal system morphogenesisGO:0048704930.020
chemosensory behaviorGO:000763510.020
peptide transportGO:001583310.020
dicarboxylic acid transportGO:000683510.020
mitochondrial transportGO:000683920.020
ribonucleoside monophosphate catabolic processGO:000915840.020
blood vessel morphogenesisGO:00485142160.020
regulation of synaptic plasticityGO:004816710.020
carbohydrate homeostasisGO:003350010.020
regulation of cytokine productionGO:000181730.020
lateral line developmentGO:0048882660.020
regulation of nucleocytoplasmic transportGO:004682220.020
cellular amino acid metabolic processGO:000652070.019
phosphorus metabolic processGO:00067931090.019
cilium assemblyGO:0042384580.019
rna biosynthetic processGO:00327741810.019
protein polymerizationGO:005125840.019
positive regulation of cytoskeleton organizationGO:005149530.019
sensory system developmentGO:0048880760.019
hormone secretionGO:004687920.019
positive regulation of cellular catabolic processGO:003133130.019
organic cyclic compound biosynthetic processGO:19013622230.019
regulation of reactive oxygen species metabolic processGO:200037720.019
response to monosaccharideGO:003428430.019
meiotic cell cycle processGO:190304630.019
regenerationGO:0031099910.019
carboxylic acid metabolic processGO:0019752220.019
neuroblast proliferationGO:000740520.019
autophagyGO:000691440.019
actin polymerization or depolymerizationGO:000815420.018
regulation of apoptotic processGO:0042981980.018
cell morphogenesis involved in neuron differentiationGO:00486671630.018
cellular response to starvationGO:000926710.018
biosynthetic processGO:00090582940.018
regulation of protein modification by small protein conjugation or removalGO:190332030.018
taxisGO:00423301090.018
growthGO:00400071740.018
regulation of multicellular organismal processGO:00512392770.018
cellular biosynthetic processGO:00442492860.018
cellular component assemblyGO:00226071700.018
rna metabolic processGO:00160702190.018
somatic muscle developmentGO:000752540.018
embryonic heart tube developmentGO:00350501330.018
pancreas developmentGO:0031016840.018
gastrulation with mouth forming secondGO:0001702440.018
regulation of wound healingGO:006104120.018
regulation of rna metabolic processGO:00512522240.018
oxoacid metabolic processGO:0043436310.018
locomotor rhythmGO:004547530.018
regulation of protein complex assemblyGO:004325430.017
membrane invaginationGO:001032410.017
response to glucoseGO:000974930.017
regulation of nucleobase containing compound metabolic processGO:00192192500.017
negative regulation of epithelial cell proliferationGO:005068010.017
positive regulation of cell divisionGO:005178120.017
phosphorylationGO:0016310690.017
hemopoiesisGO:00300971830.017
mitotic dna integrity checkpointGO:004477440.017
cortical actin cytoskeleton organizationGO:003086610.017
mitotic dna damage checkpointGO:004477340.017
protein modification processGO:00362111000.017
adherens junction organizationGO:003433240.017
regulation of cell deathGO:00109411030.017
regulation of exocytosisGO:001715710.017
segmentationGO:0035282970.017
gland developmentGO:00487321430.017
b cell activationGO:004211320.017
cellular macromolecule biosynthetic processGO:00346452240.017
skeletal system morphogenesisGO:00487051020.017
regulation of localizationGO:00328791040.017
cellular protein metabolic processGO:00442671290.017
heart morphogenesisGO:00030071560.017
programmed cell deathGO:00125011190.017
immune system processGO:00023762410.017
forebrain developmentGO:0030900960.017
positive regulation of cytokine productionGO:000181920.017
neurotransmitter secretionGO:000726920.017
regulation of cellular protein catabolic processGO:190336210.017
hepaticobiliary system developmentGO:0061008980.016
regulation of tube sizeGO:003515020.016
establishment of localization in cellGO:0051649770.016
stem cell differentiationGO:00488631170.016
regulation of nitrogen compound metabolic processGO:00511712510.016
negative regulation of kinase activityGO:003367340.016
negative regulation of protein serine threonine kinase activityGO:007190120.016
positive regulation of cellular processGO:00485222010.016
otic vesicle developmentGO:0071599420.016
positive regulation of dna metabolic processGO:005105410.016
sleepGO:003043110.016
synaptic transmission cholinergicGO:000727140.016
regulation of oocyte developmentGO:006028130.016
amino acid transportGO:000686520.016
regulation of cell developmentGO:00602841000.016
mesenchymal cell differentiationGO:0048762870.016
cartilage developmentGO:0051216960.016
fertilizationGO:000956630.016
epithelial cell differentiationGO:00308551160.016
purine nucleoside monophosphate catabolic processGO:000912840.016
regulation of cell differentiationGO:00455951420.016
cilium organizationGO:0044782710.016
regulation of dna replicationGO:000627530.016
regulation of neural precursor cell proliferationGO:200017730.016
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.016
embryonic cranial skeleton morphogenesisGO:0048701900.016
regulation of reproductive processGO:200024140.016
mesenchyme developmentGO:00604851270.016
cellular response to molecule of bacterial originGO:007121930.016
homeostatic processGO:00425921420.016
liver developmentGO:0001889960.016
g2 dna damage checkpointGO:003157230.016
regulation of programmed cell deathGO:00430671010.016
regulation of response to stimulusGO:00485832690.016
developmental growth involved in morphogenesisGO:0060560860.016
glucose homeostasisGO:004259310.015
regulation of macromolecule biosynthetic processGO:00105562250.015
connective tissue developmentGO:0061448990.015
regulation of transmembrane transporter activityGO:002289820.015
regulation of circadian rhythmGO:004275240.015
g2 m transition of mitotic cell cycleGO:000008640.015
hematopoietic or lymphoid organ developmentGO:00485341910.015
positive regulation of secretionGO:005104710.015
calcium ion transport into cytosolGO:006040230.015
positive regulation of protein complex assemblyGO:003133420.015
positive regulation of canonical wnt signaling pathwayGO:009026340.015
cytoskeleton organizationGO:0007010960.015
microtubule cytoskeleton organizationGO:0000226330.015
sequestering of calcium ionGO:005120830.015
regulation of cellular biosynthetic processGO:00313262450.015
regulation of microtubule cytoskeleton organizationGO:007050730.015
regulation of protein bindingGO:004339330.015
nucleobase containing compound biosynthetic processGO:00346542050.015
single organism membrane fusionGO:004480120.015
regulation of sequestering of calcium ionGO:005128240.015
regulation of cell morphogenesis involved in differentiationGO:0010769380.015
positive regulation of small gtpase mediated signal transductionGO:005105710.015
primary neural tube formationGO:001402010.015
regulation of cell activationGO:005086510.015
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.015
positive regulation of cell adhesionGO:004578510.015
negative regulation of cell communicationGO:0010648960.015
cortical cytoskeleton organizationGO:003086510.014
regulation of cellular macromolecule biosynthetic processGO:20001122220.014
regulation of protein import into nucleusGO:004230620.014
neuron neuron synaptic transmissionGO:000727010.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
response to nutrientGO:000758430.014
regulation of transporter activityGO:003240920.014
somatic stem cell maintenanceGO:003501910.014
cellular response to biotic stimulusGO:007121630.014
regulation of hormone secretionGO:004688320.014
macromolecule modificationGO:00434121110.014
cell killingGO:000190620.014
axis specificationGO:0009798430.014
cytosolic calcium ion transportGO:006040130.014
axon guidanceGO:0007411860.014
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.014
regulation of neurotransmitter secretionGO:004692810.014
angiogenesisGO:00015251580.014
cell deathGO:00082191210.014
cell substrate adhesionGO:003158940.014
regulation of cell shapeGO:000836010.014
response to external stimulusGO:00096052640.014
positive regulation of epithelial cell migrationGO:001063420.014
regulation of wnt signaling pathwayGO:0030111530.014
wound healingGO:0042060900.014
kupffer s vesicle developmentGO:0070121500.014
regulation of nervous system developmentGO:0051960900.014
tissue remodelingGO:004877140.014
sequestering of metal ionGO:005123830.014
immune system developmentGO:00025201910.014
negative regulation of stem cell differentiationGO:200073720.014
response to endogenous stimulusGO:0009719830.014
enzyme linked receptor protein signaling pathwayGO:00071671060.014
protein stabilizationGO:005082120.014
mesoderm developmentGO:0007498880.014
macromolecule biosynthetic processGO:00090592270.014
neuromuscular synaptic transmissionGO:000727420.014
apoptotic processGO:00069151160.014
positive regulation of epithelial cell proliferationGO:005067910.013
response to abiotic stimulusGO:00096281220.013
organelle fusionGO:004828430.013
response to organic substanceGO:00100331530.013
positive regulation of metabolic processGO:00098931080.013
protein depolymerizationGO:005126110.013
cell cycle arrestGO:000705010.013
positive regulation of multicellular organismal processGO:0051240520.013
regulation of calcium ion transportGO:005192420.013
development of primary female sexual characteristicsGO:004654540.013
negative regulation of signal transductionGO:0009968940.013
response to radiationGO:0009314510.013
behaviorGO:0007610740.013
system processGO:00030081850.013
pole plasm assemblyGO:000731540.013
tube closureGO:006060610.013
regulation of canonical wnt signaling pathwayGO:0060828340.013
regulation of neurogenesisGO:0050767870.013
negative regulation of wnt signaling pathwayGO:0030178300.013
organism emergence from protective structureGO:007168440.013
actin filament polymerizationGO:003004120.013
establishment of synaptic vesicle localizationGO:009748010.013
centrosome organizationGO:005129710.013
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.013
axon extensionGO:0048675450.013
carbohydrate derivative metabolic processGO:1901135610.013
antimicrobial humoral responseGO:001973020.013
cellular component maintenanceGO:004395430.013
negative regulation of protein transportGO:005122430.013
eye morphogenesisGO:00485921440.013
negative regulation of synapse assemblyGO:005196420.013
positive regulation of immune effector processGO:000269930.012
peptidyl threonine modificationGO:001821010.012
nephron morphogenesisGO:007202820.012
negative regulation of intracellular transportGO:003238730.012
positive regulation of cellular metabolic processGO:0031325940.012
regulation of nucleotide catabolic processGO:003081120.012
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.012
membrane fusionGO:006102520.012
response to amino acidGO:004320020.012
er to golgi vesicle mediated transportGO:000688810.012
neural crest cell differentiationGO:0014033720.012
positive regulation of ras protein signal transductionGO:004657910.012
synaptic vesicle localizationGO:009747910.012
negative regulation of mitosisGO:004583930.012
regulation of blood pressureGO:000821710.012
regulation of neuron differentiationGO:0045664560.012
deathGO:00162651210.012
transcription dna templatedGO:00063511810.012
response to alkaloidGO:004327920.012
symbiosis encompassing mutualism through parasitismGO:004440340.012
female sex differentiationGO:004666040.012
cell cycle g2 m phase transitionGO:004483940.012
post embryonic organ developmentGO:004856940.012
appendage morphogenesisGO:0035107560.012
centrosome cycleGO:000709810.012
regulation of blood vessel sizeGO:005088020.012
otic vesicle morphogenesisGO:0071600340.012
multi organism processGO:00517041340.012
cytokinetic processGO:003250620.012
ras protein signal transductionGO:000726570.012
transcription from rna polymerase ii promoterGO:0006366800.012
regulation of transcription dna templatedGO:00063552130.012
negative regulation of secretionGO:005104820.012
regulation of neurotransmitter transportGO:005158810.012
compound eye developmentGO:004874920.012
positive regulation of wound healingGO:009030310.012
muscle structure developmentGO:00610611960.012
lateral inhibitionGO:004633110.012
regulation of primary metabolic processGO:00800903110.012
somitogenesisGO:0001756870.012
regulation of dendrite developmentGO:005077330.012
regulation of protein ubiquitinationGO:003139630.012
astrocyte differentiationGO:004870810.012
meiotic chromosome segregationGO:004513230.012
startle responseGO:000196440.012
cellular protein complex disassemblyGO:004362410.012
regulation of cell migrationGO:0030334400.012
regulation of endocrine processGO:004406020.012
regulation of protein complex disassemblyGO:004324410.012
fin developmentGO:0033333770.012
notochord developmentGO:0030903540.011
regulation of purine nucleotide catabolic processGO:003312120.011
nephron tubule morphogenesisGO:007207810.011
response to woundingGO:00096111160.011
protein acetylationGO:000647320.011
release of sequestered calcium ion into cytosolGO:005120930.011
cytoplasm organizationGO:000702840.011

frmd8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.037
nervous system diseaseDOID:86300.019
disease of cellular proliferationDOID:1456600.018
cancerDOID:16200.016
organ system cancerDOID:005068600.016
disease of metabolismDOID:001466700.014
sensory system diseaseDOID:005015500.013
eye and adnexa diseaseDOID:149200.013
eye diseaseDOID:561400.013
immune system diseaseDOID:291400.012
cardiovascular system diseaseDOID:128700.012