Danio rerio

0 known processes

hsd17b12b

hydroxysteroid (17-beta) dehydrogenase 12b

(Aliases: zgc:73289,fb68b12,wu:fb68b12)

hsd17b12b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of biological qualityGO:00650082630.372
Zebrafish Worm
larval developmentGO:000216420.310
Worm
androgen metabolic processGO:000820920.294
Zebrafish Worm
female sex differentiationGO:004666040.212
Worm
dicarboxylic acid metabolic processGO:004364810.183
agingGO:000756820.167
Worm
embryonic organ morphogenesisGO:00485622740.162
membrane lipid biosynthetic processGO:004646720.158
Yeast
signal transductionGO:00071654550.153
regulation of response to stimulusGO:00485832690.140
organic substance biosynthetic processGO:19015762890.129
Yeast Zebrafish Worm
cell deathGO:00082191210.127
embryonic organ developmentGO:00485683810.122
regulation of signalingGO:00230512350.114
single organism metabolic processGO:00447102170.112
Yeast Zebrafish Worm
androgen biosynthetic processGO:000670210.111
Zebrafish
positive regulation of cytokine productionGO:000181920.108
programmed cell deathGO:00125011190.107
cellular biosynthetic processGO:00442492860.104
Yeast Zebrafish Worm
very long chain fatty acid biosynthetic processGO:004276140.104
Yeast
very long chain fatty acid metabolic processGO:000003840.096
Yeast
regulation of signal transductionGO:00099662250.095
single organism biosynthetic processGO:0044711710.095
Yeast Zebrafish Worm
organelle organizationGO:00069962270.094
deathGO:00162651210.092
hormone metabolic processGO:0042445190.083
Zebrafish Worm
fatty acid elongationGO:003049710.079
Yeast
regulation of multicellular organismal processGO:00512392770.076
organic cyclic compound biosynthetic processGO:19013622230.075
Zebrafish Worm
locomotionGO:00400113130.075
Worm
cellular response to nutrient levelsGO:003166920.074
central nervous system developmentGO:00074173870.070
cellular component movementGO:00069283350.069
positive regulation of biological processGO:00485182530.068
Mouse
lipid storageGO:001991510.067
hormone biosynthetic processGO:004244630.065
Zebrafish
long chain fatty acid biosynthetic processGO:004275910.064
Worm
brain developmentGO:00074202930.064
single organism localizationGO:19025782250.063
lipid biosynthetic processGO:0008610220.061
Yeast Zebrafish Worm
angiogenesisGO:00015251580.060
neuron developmentGO:00486662620.060
response to organic substanceGO:00100331530.059
organonitrogen compound metabolic processGO:1901564740.059
Yeast
negative regulation of biological processGO:00485193040.059
stem cell maintenanceGO:001982740.059
regulation of cytokine productionGO:000181730.059
transmembrane transportGO:00550851200.058
specification of symmetryGO:00097992040.057
regulation of muscle contractionGO:000693730.057
regulation of tube sizeGO:003515020.057
apoptotic processGO:00069151160.056
cellular response to external stimulusGO:007149620.053
atp catabolic processGO:000620040.053
mesenchyme developmentGO:00604851270.053
regulation of transcription from rna polymerase ii promoter in response to oxidative stressGO:004361900.053
regulation of dna templated transcription in response to stressGO:004362000.053
zinc ion homeostasisGO:005506910.052
regulation of cell deathGO:00109411030.051
regulation of multicellular organismal developmentGO:20000262230.051
mechanosensory lateral line system developmentGO:0048881490.051
ion homeostasisGO:0050801410.051
regulation of blood pressureGO:000821710.051
regulation of multicellular organism growthGO:004001440.050
regulation of programmed cell deathGO:00430671010.050
oxidation reduction processGO:0055114410.050
Yeast Zebrafish Worm
liver developmentGO:0001889960.050
biosynthetic processGO:00090582940.049
Yeast Zebrafish Worm
ribonucleoside monophosphate catabolic processGO:000915840.049
alpha amino acid metabolic processGO:190160530.048
neuromast developmentGO:0048884460.047
gastrulationGO:00073692080.047
carboxylic acid biosynthetic processGO:0046394120.046
Yeast Worm
determination of bilateral symmetryGO:00098552040.045
organic acid biosynthetic processGO:0016053120.045
Yeast Worm
homeostatic processGO:00425921420.045
positive regulation of cellular processGO:00485222010.044
Mouse
inner ear developmentGO:00488391260.043
cellular response to organic substanceGO:00713101050.043
stem cell differentiationGO:00488631170.043
maintenance of locationGO:005123540.043
cellular response to chemical stimulusGO:00708871570.042
cellular response to starvationGO:000926710.042
neuron differentiationGO:00301823530.042
regulation of reproductive processGO:200024140.042
negative regulation of cellular processGO:00485232830.041
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.041
actomyosin structure organizationGO:0031032530.041
regulation of cell communicationGO:00106462320.041
multicellular organismal response to stressGO:003355520.041
Zebrafish
cellular response to extracellular stimulusGO:003166820.040
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217520.040
regulation of nucleic acid templated transcriptionGO:19035062130.040
stem cell developmentGO:0048864820.039
metal ion homeostasisGO:0055065260.039
cellular modified amino acid metabolic processGO:000657530.038
sensory organ developmentGO:00074233930.038
macromolecule localizationGO:0033036540.038
smooth muscle contractionGO:000693920.037
hepaticobiliary system developmentGO:0061008980.037
positive regulation of stress activated mapk cascadeGO:003287430.037
cell death in response to oxidative stressGO:003647320.036
oxoacid metabolic processGO:0043436310.036
Yeast Worm
generation of neuronsGO:00486993850.036
mesenchymal cell differentiationGO:0048762870.036
regulation of rna biosynthetic processGO:20011412130.036
establishment of localizationGO:00512342440.035
synaptic vesicle localizationGO:009747910.035
reactive oxygen species biosynthetic processGO:190340910.035
nik nf kappab signalingGO:003806110.035
proteolysis involved in cellular protein catabolic processGO:005160330.035
single organism organelle organizationGO:19025891990.034
estrogen metabolic processGO:000821020.034
Worm
monocarboxylic acid biosynthetic processGO:0072330120.034
Yeast Worm
response to stressGO:00069502630.034
Zebrafish
ovulation cycle processGO:002260220.033
regulation of protein catabolic processGO:004217610.033
protein metabolic processGO:00195381830.033
positive regulation of cell cycleGO:004578730.032
cellular amide metabolic processGO:004360340.032
ovulation cycleGO:004269820.032
nucleobase containing compound metabolic processGO:00061392740.032
fatty acid biosynthetic processGO:000663340.032
Yeast Worm
immune system processGO:00023762410.031
cellular nitrogen compound metabolic processGO:00346412900.031
purine nucleoside monophosphate catabolic processGO:000912840.031
negative regulation of catabolic processGO:000989530.031
small molecule catabolic processGO:004428230.031
regulation of protein ubiquitinationGO:003139630.031
response to topologically incorrect proteinGO:003596620.030
cellular response to topologically incorrect proteinGO:003596720.030
cellular component morphogenesisGO:00329893360.030
germ line stem cell maintenanceGO:003071820.030
response to lipidGO:0033993600.030
cellular nitrogen compound biosynthetic processGO:00442712180.030
macromolecule biosynthetic processGO:00090592270.030
regulation of cellular macromolecule biosynthetic processGO:20001122220.030
regulation of reactive oxygen species metabolic processGO:200037720.029
regulation of developmental processGO:00507932470.029
nucleobase containing compound biosynthetic processGO:00346542050.029
muscle cell developmentGO:00550011150.028
regulation of apoptotic processGO:0042981980.028
regionalizationGO:00030022740.028
steroid biosynthetic processGO:000669450.028
Zebrafish Worm
cell part morphogenesisGO:00329902460.028
multicellular organism growthGO:003526440.028
response to glucocorticoidGO:005138410.027
heterocycle biosynthetic processGO:00181302150.027
transcription from rna polymerase ii promoterGO:0006366800.027
regulation of cell activationGO:005086510.026
chordate embryonic developmentGO:00430092710.026
zymogen activationGO:003163830.026
small molecule biosynthetic processGO:0044283160.026
Yeast Worm
regulation of oxidative stress induced cell deathGO:190320120.026
response to carbohydrateGO:000974330.026
cell motilityGO:00488702440.025
iron ion homeostasisGO:005507240.025
cellular response to unfolded proteinGO:003462020.025
cell agingGO:000756920.025
negative regulation of developmental processGO:0051093650.025
cellular protein catabolic processGO:004425740.025
organic cyclic compound metabolic processGO:19013603010.025
Zebrafish Worm
regulation of stem cell differentiationGO:200073640.025
regulation of response to nutrient levelsGO:003210710.025
carboxylic acid metabolic processGO:0019752220.024
Yeast Worm
lateral line developmentGO:0048882660.024
establishment of protein localization to organelleGO:007259440.024
female gonad developmentGO:000858540.024
response to nutrientGO:000758430.024
regulation of rac protein signal transductionGO:003502010.024
response to fatty acidGO:007054250.023
determination of left right symmetryGO:00073681790.023
cellular aromatic compound metabolic processGO:00067252950.023
cell migrationGO:00164772370.023
lipid metabolic processGO:0006629520.023
Yeast Zebrafish Worm
development of primary female sexual characteristicsGO:004654540.023
regulation of hormone metabolic processGO:003235060.022
Worm
cellular amino acid metabolic processGO:000652070.022
transportGO:00068102200.022
multi organism processGO:00517041340.022
embryonic cranial skeleton morphogenesisGO:0048701900.022
determination of heart left right asymmetryGO:00613711170.022
establishment of localization in cellGO:0051649770.022
synaptic vesicle transportGO:004848910.022
embryonic skeletal system developmentGO:0048706970.021
positive regulation of nitrogen compound metabolic processGO:0051173690.021
cellular macromolecule metabolic processGO:00442603910.021
small molecule metabolic processGO:0044281770.021
Yeast Worm
cellular protein metabolic processGO:00442671290.021
cellular component biogenesisGO:00440851780.021
regulation of establishment of protein localizationGO:007020140.021
negative regulation of apoptotic processGO:0043066550.020
cellular macromolecule biosynthetic processGO:00346452240.020
hydrogen peroxide metabolic processGO:004274320.020
regulation of protein modification by small protein conjugation or removalGO:190332030.020
skeletal system developmentGO:00015011810.020
response to chemicalGO:00422213200.020
modification dependent macromolecule catabolic processGO:004363230.020
negative regulation of multicellular organismal processGO:0051241690.020
ion transportGO:00068111140.020
sensory system developmentGO:0048880760.020
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:004278710.020
single organism transportGO:00447652060.019
lateral line system developmentGO:0048925760.019
response to corticosteroidGO:003196010.019
cell type specific apoptotic processGO:0097285220.019
negative regulation of reproductive processGO:200024230.019
establishment of synaptic vesicle localizationGO:009748010.019
response to external stimulusGO:00096052640.019
blood vessel morphogenesisGO:00485142160.019
modification dependent protein catabolic processGO:001994130.019
protein secretionGO:000930610.019
mitochondrion organizationGO:000700540.019
muscle contractionGO:0006936180.019
er nucleus signaling pathwayGO:000698420.019
regulation of protein complex assemblyGO:004325430.019
developmental growthGO:00485891660.018
positive regulation of neuron deathGO:190121610.018
peptidyl serine phosphorylationGO:001810510.018
nucleic acid metabolic processGO:00903042440.018
regulation of response to oxidative stressGO:190288220.018
regulation of anatomical structure morphogenesisGO:00226031300.018
ubiquitin dependent protein catabolic processGO:000651130.018
embryo development ending in birth or egg hatchingGO:00097922710.018
Worm
regulation of anatomical structure sizeGO:0090066330.018
cellular response to lipidGO:0071396390.018
endosomal transportGO:001619720.018
mitochondrial transportGO:000683920.018
heterocycle metabolic processGO:00464832900.018
endoplasmic reticulum unfolded protein responseGO:003096820.018
forebrain cell migrationGO:002188510.018
alcohol biosynthetic processGO:004616520.018
regulation of cellular protein catabolic processGO:190336210.018
regulation of jak stat cascadeGO:004642530.018
regulation of primary metabolic processGO:00800903110.018
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.018
heart morphogenesisGO:00030071560.017
embryonic heart tube morphogenesisGO:00031431080.017
regulation of biosynthetic processGO:00098892500.017
calcium ion importGO:007050940.017
negative regulation of signal transductionGO:0009968940.017
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.017
protein complex biogenesisGO:0070271300.017
calcium ion transport into cytosolGO:006040230.016
regulation of localizationGO:00328791040.016
nitric oxide biosynthetic processGO:000680920.016
gene expressionGO:00104672520.016
blood circulationGO:0008015870.016
embryonic skeletal system morphogenesisGO:0048704930.016
negative regulation of cell communicationGO:0010648960.016
heart loopingGO:0001947940.016
regulation of nucleobase containing compound metabolic processGO:00192192500.016
response to endogenous stimulusGO:0009719830.016
macroautophagyGO:001623610.016
regulation of metabolic processGO:00192223590.016
Worm
cellular response to oxygen radicalGO:007145020.016
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.016
system processGO:00030081850.016
localization of cellGO:00516742440.016
guanosine containing compound metabolic processGO:190106840.016
axon developmentGO:00615641660.016
intracellular transportGO:0046907320.016
regulation of cellular metabolic processGO:00313233200.016
growthGO:00400071740.015
protein complex assemblyGO:0006461300.015
sensory perception of chemical stimulusGO:000760630.015
regulation of rna metabolic processGO:00512522240.015
negative regulation of cellular catabolic processGO:003133030.015
negative regulation of programmed cell deathGO:0043069580.015
oocyte maturationGO:000155640.015
b cell activationGO:004211320.015
compound eye developmentGO:004874920.015
neuron deathGO:0070997210.015
single organism intracellular transportGO:1902582250.015
nitrogen compound metabolic processGO:00068073190.015
Yeast
head developmentGO:00603223030.015
protein homooligomerizationGO:005126030.015
regulation of autophagyGO:001050630.015
tyrosine phosphorylation of stat proteinGO:000726010.015
ear developmentGO:00435831270.015
photoreceptor cell outer segment organizationGO:003584590.015
regulation of systemic arterial blood pressureGO:000307310.015
germ line stem cell divisionGO:004207810.014
positive regulation of immune effector processGO:000269930.014
carbohydrate homeostasisGO:003350010.014
forebrain developmentGO:0030900960.014
response to alkaloidGO:004327920.014
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217620.014
cell morphogenesisGO:00009022890.014
organic substance transportGO:0071702580.014
cellular response to molecule of bacterial originGO:007121930.014
neural crest cell differentiationGO:0014033720.014
nucleoside monophosphate catabolic processGO:000912540.014
cell morphogenesis involved in differentiationGO:00009041950.014
rna metabolic processGO:00160702190.014
regulation of cellular response to oxidative stressGO:190040720.014
organic acid metabolic processGO:0006082310.014
Yeast Worm
synaptic target recognitionGO:000803910.013
energy reserve metabolic processGO:000611220.013
regulation of inflammatory responseGO:005072720.013
cell projection morphogenesisGO:00488582440.013
proteasomal protein catabolic processGO:001049820.013
protein importGO:001703830.013
cellular component assemblyGO:00226071700.013
regulation of purine nucleotide catabolic processGO:003312120.013
developmental growth involved in morphogenesisGO:0060560860.013
cellular carbohydrate metabolic processGO:004426240.013
epithelial to mesenchymal transitionGO:0001837210.013
positive regulation of macromolecule metabolic processGO:0010604930.013
regulation of cellular biosynthetic processGO:00313262450.013
cytoskeleton dependent cytokinesisGO:006164030.013
positive regulation of programmed cell deathGO:0043068290.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.013
positive regulation of rna biosynthetic processGO:1902680570.013
embryonic viscerocranium morphogenesisGO:0048703520.013
response to drugGO:004249330.013
embryonic heart tube developmentGO:00350501330.013
neurotransmitter secretionGO:000726920.013
regulation of locomotionGO:0040012550.013
myeloid cell homeostasisGO:0002262560.012
cellular transition metal ion homeostasisGO:004691630.012
positive regulation of cell divisionGO:005178120.012
protein modification processGO:00362111000.012
inner ear receptor cell differentiationGO:0060113290.012
response to monosaccharideGO:003428430.012
protein stabilizationGO:005082120.012
negative regulation of cell deathGO:0060548600.012
nitric oxide metabolic processGO:004620920.012
digestive tract morphogenesisGO:00485462310.012
cation homeostasisGO:0055080330.012
long chain fatty acid metabolic processGO:000167610.012
Worm
regulation of protein transportGO:005122330.012
ovarian follicle developmentGO:000154120.012
cell migration involved in gastrulationGO:0042074790.012
negative regulation of translationGO:001714810.012
regulation of response to extracellular stimulusGO:003210410.012
hematopoietic stem cell differentiationGO:0060218200.012
chemical homeostasisGO:0048878490.012
neuron apoptotic processGO:0051402200.012
negative regulation of cellular metabolic processGO:0031324770.012
photoreceptor cell differentiationGO:0046530550.012
regulation of cellular component movementGO:0051270550.012
regulation of production of molecular mediator of immune responseGO:000270010.011
peripheral nervous system developmentGO:0007422550.011
nucleic acid templated transcriptionGO:00976591810.011
positive regulation of response to stimulusGO:0048584800.011
skeletal system morphogenesisGO:00487051020.011
photoreceptor cell developmentGO:0042461400.011
cytoskeleton organizationGO:0007010960.011
gland developmentGO:00487321430.011
intracellular signal transductionGO:0035556850.011
regulation of wnt signaling pathwayGO:0030111530.011
apoptotic signaling pathwayGO:0097190230.011
negative regulation of nuclear divisionGO:005178430.011
epithelial cell developmentGO:0002064420.011
regulation of bindingGO:005109830.011
cell morphogenesis involved in neuron differentiationGO:00486671630.011
regulation of synaptic plasticityGO:004816710.011
purine ribonucleoside monophosphate catabolic processGO:000916940.011
pigmentationGO:0043473850.011
mesoderm developmentGO:0007498880.011
muscle cell differentiationGO:00426921390.011
regulation of cell differentiationGO:00455951420.011
dorsal ventral pattern formationGO:00099531250.011
blood vessel developmentGO:00015682460.011
regulation of hematopoietic progenitor cell differentiationGO:190153210.011
negative regulation of multi organism processGO:004390130.011
macromolecular complex assemblyGO:0065003350.011
neuron projection morphogenesisGO:00488121610.011
lipid oxidationGO:003444010.011
response to abiotic stimulusGO:00096281220.011
negative regulation of signalingGO:0023057960.011
response to unfolded proteinGO:000698620.010
transcription dna templatedGO:00063511810.010
divalent inorganic cation homeostasisGO:0072507220.010
positive regulation of metabolic processGO:00098931080.010
positive regulation of transportGO:005105020.010
response to uvGO:000941130.010
negative regulation of kinase activityGO:003367340.010
connective tissue developmentGO:0061448990.010
regulation of nitrogen compound metabolic processGO:00511712510.010
regulation of sequence specific dna binding transcription factor activityGO:005109090.010
regulation of cell substrate adhesionGO:001081010.010
Mouse
gamete generationGO:0007276330.010
immune system developmentGO:00025201910.010
calcium mediated signalingGO:001972220.010
production of molecular mediator of immune responseGO:000244020.010
carboxylic acid catabolic processGO:004639530.010
positive regulation of dna metabolic processGO:005105410.010
reproductive processGO:0022414400.010
Worm

hsd17b12b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.136
nervous system diseaseDOID:86300.085
motor neuron diseaseDOID:23100.043
central nervous system diseaseDOID:33100.043
neurodegenerative diseaseDOID:128900.043
amyotrophic lateral sclerosisDOID:33200.043
disease of metabolismDOID:001466700.033
inherited metabolic disorderDOID:65500.033
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.015
sensory system diseaseDOID:005015500.013