Danio rerio

0 known processes

rag2

recombination activating gene 2

(Aliases: MGC136743,zgc:136743,rag-2)

rag2 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic cyclic compound biosynthetic processGO:19013622230.660
cellular nitrogen compound metabolic processGO:00346412900.649
Mouse
regulation of metabolic processGO:00192223590.557
Mouse
gene expressionGO:00104672520.465
Mouse
hematopoietic or lymphoid organ developmentGO:00485341910.453
Mouse
regulation of primary metabolic processGO:00800903110.427
small molecule metabolic processGO:0044281770.398
nitrogen compound metabolic processGO:00068073190.395
Mouse
regulation of nitrogen compound metabolic processGO:00511712510.379
gastrulation with mouth forming secondGO:0001702440.379
epithelial cell developmentGO:0002064420.363
cellular aromatic compound metabolic processGO:00067252950.344
Mouse
organic substance biosynthetic processGO:19015762890.343
cellular nitrogen compound biosynthetic processGO:00442712180.340
development of primary female sexual characteristicsGO:004654540.334
organonitrogen compound metabolic processGO:1901564740.304
aromatic compound biosynthetic processGO:00194382170.285
immune system developmentGO:00025201910.262
Mouse
transcription from rna polymerase ii promoterGO:0006366800.244
digestive system developmentGO:00551232890.242
negative regulation of biological processGO:00485193040.241
regionalizationGO:00030022740.240
gastrulationGO:00073692080.238
regulation of cyclic nucleotide biosynthetic processGO:0030802150.234
convergent extension involved in organogenesisGO:0060029100.229
nucleobase containing compound metabolic processGO:00061392740.226
Mouse
organic cyclic compound metabolic processGO:19013603010.223
Mouse
nucleobase containing compound biosynthetic processGO:00346542050.213
regulation of multicellular organismal processGO:00512392770.191
Mouse
female sex differentiationGO:004666040.185
tube morphogenesisGO:00352393490.177
female gonad developmentGO:000858540.176
regulation of biological qualityGO:00650082630.175
heterocycle biosynthetic processGO:00181302150.172
regulation of hormone secretionGO:004688320.165
morphogenesis of an epitheliumGO:00020093330.162
ovulation cycleGO:004269820.144
multi organism processGO:00517041340.144
circadian sleep wake cycle sleepGO:005080210.143
maintenance of locationGO:005123540.141
nephron morphogenesisGO:007202820.139
regulation of developmental processGO:00507932470.138
Mouse
single organism metabolic processGO:00447102170.133
cell projection organizationGO:00300302840.131
biosynthetic processGO:00090582940.129
regulation of cellular metabolic processGO:00313233200.124
sleepGO:003043110.120
response to chemicalGO:00422213200.117
negative regulation of multicellular organismal processGO:0051241690.116
homeostatic processGO:00425921420.115
regulation of biosynthetic processGO:00098892500.115
regulation of photoreceptor cell differentiationGO:004653220.114
immune system processGO:00023762410.110
Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.108
growth plate cartilage morphogenesisGO:000342210.108
digestive tract developmentGO:00485652650.107
multicellular organism reproductionGO:0032504350.107
regulation of response to stimulusGO:00485832690.106
leukocyte differentiationGO:0002521250.103
Mouse
epiboly involved in gastrulation with mouth forming secondGO:0055113350.100
epithelial cell differentiationGO:00308551160.097
gamete generationGO:0007276330.096
regulation of metal ion transportGO:001095940.092
heterocycle metabolic processGO:00464832900.091
Mouse
amine metabolic processGO:000930820.091
negative regulation of cyclic nucleotide biosynthetic processGO:003080370.091
segmentationGO:0035282970.090
gland developmentGO:00487321430.090
cell volume homeostasisGO:000688410.089
g protein coupled receptor signaling pathwayGO:0007186740.088
organelle assemblyGO:00709251100.088
cyclic nucleotide biosynthetic processGO:0009190180.087
cellular component movementGO:00069283350.085
epibolyGO:0090504410.084
regulation of rna metabolic processGO:00512522240.084
cellular ketone metabolic processGO:0042180110.083
camp metabolic processGO:0046058110.082
reproductionGO:0000003400.081
regulation of circadian sleep wake cycleGO:004274910.081
regulation of sodium ion transportGO:000202820.080
agingGO:000756820.080
carbohydrate derivative biosynthetic processGO:1901137430.080
positive regulation of cellular metabolic processGO:0031325940.078
cellular macromolecule biosynthetic processGO:00346452240.078
cellular macromolecule metabolic processGO:00442603910.078
Mouse
reproductive processGO:0022414400.077
transcription dna templatedGO:00063511810.076
negative regulation of innate immune responseGO:004582420.075
positive regulation of apoptotic signaling pathwayGO:200123510.073
negative regulation of cyclic nucleotide metabolic processGO:003080070.073
endothelium developmentGO:0003158250.072
response to external stimulusGO:00096052640.070
rna metabolic processGO:00160702190.069
regulation of cellular amine metabolic processGO:003323800.068
circadian sleep wake cycle processGO:002241020.068
cell deathGO:00082191210.067
macromolecule biosynthetic processGO:00090592270.066
multicellular organismal reproductive processGO:0048609350.065
regulation of reproductive processGO:200024140.064
positive regulation of gene expressionGO:0010628710.063
blood circulationGO:0008015870.063
cellular amino acid metabolic processGO:000652070.063
system processGO:00030081850.062
larval developmentGO:000216420.062
regulation of signal transductionGO:00099662250.061
embryo development ending in birth or egg hatchingGO:00097922710.060
neurological system processGO:0050877620.059
regulation of nucleobase containing compound metabolic processGO:00192192500.059
cellular biosynthetic processGO:00442492860.058
negative regulation of feeding behaviorGO:200025220.056
locomotionGO:00400113130.055
lymphocyte differentiationGO:003009890.055
Mouse
cellular amine metabolic processGO:004410620.055
ovulation cycle processGO:002260220.055
regulation of circadian sleep wake cycle sleepGO:004518710.055
regulation of rna biosynthetic processGO:20011412130.054
sexual reproductionGO:0019953360.054
negative regulation of hormone secretionGO:004688820.054
signal transductionGO:00071654550.053
regulation of macromolecule metabolic processGO:00602553170.053
Mouse
striated muscle cell differentiationGO:00511461290.053
regulation of cellular biosynthetic processGO:00313262450.052
regulation of camp metabolic processGO:003081490.052
positive regulation of nitrogen compound metabolic processGO:0051173690.052
nucleic acid metabolic processGO:00903042440.050
Mouse
intracellular estrogen receptor signaling pathwayGO:003052030.050
t cell differentiation in thymusGO:003307760.050
Mouse
skeletal system developmentGO:00015011810.050
hormone secretionGO:004687920.049
neuron projection developmentGO:00311751800.048
regulation of signalingGO:00230512350.048
axon guidanceGO:0007411860.047
myofibril assemblyGO:0030239480.047
neuron differentiationGO:00301823530.047
brain developmentGO:00074202930.047
regulation of localizationGO:00328791040.046
negative regulation of camp metabolic processGO:003081570.045
regulation of camp biosynthetic processGO:003081790.045
camera type eye developmentGO:00430102220.045
positive regulation of neuron migrationGO:200122420.044
digestive tract morphogenesisGO:00485462310.044
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.044
regulation of cellular ketone metabolic processGO:001056570.044
mechanoreceptor differentiationGO:0042490370.044
mesenchyme developmentGO:00604851270.044
cell part morphogenesisGO:00329902460.044
embryonic organ developmentGO:00485683810.044
regulation of macromolecule biosynthetic processGO:00105562250.043
regulation of transcription dna templatedGO:00063552130.043
regulation of immune system processGO:0002682340.042
cytosolic calcium ion transportGO:006040130.042
eye developmentGO:00016542770.041
negative regulation of cellular processGO:00485232830.040
positive regulation of cellular biosynthetic processGO:0031328680.040
regulation of transcription from rna polymerase ii promoterGO:00063571140.040
immune responseGO:0006955280.040
hemopoiesisGO:00300971830.040
Mouse
organonitrogen compound biosynthetic processGO:1901566470.040
negative regulation of nucleotide biosynthetic processGO:003080970.039
phosphate containing compound metabolic processGO:00067961080.039
endothelial cell differentiationGO:0045446200.038
regulation of extrinsic apoptotic signaling pathwayGO:200123630.038
metal ion transportGO:0030001580.038
protein acetylationGO:000647320.038
regulation of systemic arterial blood pressureGO:000307310.038
nucleic acid templated transcriptionGO:00976591810.037
rna biosynthetic processGO:00327741810.037
epithelial tube morphogenesisGO:00605621480.037
regulation of nucleotide biosynthetic processGO:0030808150.036
regulation of nucleic acid templated transcriptionGO:19035062130.036
localization of cellGO:00516742440.036
cell projection morphogenesisGO:00488582440.036
negative regulation of nucleotide metabolic processGO:004598070.036
muscle cell differentiationGO:00426921390.036
single organism reproductive processGO:0044702400.034
thymus developmentGO:0048538100.034
somatic cell dna recombinationGO:001644410.034
Mouse
inner ear developmentGO:00488391260.033
regulation of intracellular signal transductionGO:1902531570.033
circadian sleep wake cycleGO:004274520.033
anterior posterior pattern specificationGO:00099521520.033
tube formationGO:0035148250.033
oocyte maturationGO:000155640.033
cell migrationGO:00164772370.033
negative regulation of purine nucleotide biosynthetic processGO:190037270.032
carbohydrate derivative metabolic processGO:1901135610.032
regulation of cell communicationGO:00106462320.032
neuromast developmentGO:0048884460.032
multi organism reproductive processGO:0044703360.032
negative regulation of defense responseGO:003134820.031
immune response activating signal transductionGO:000275750.031
mononuclear cell proliferationGO:003294310.031
Mouse
nephron tubule morphogenesisGO:007207810.031
muscle structure developmentGO:00610611960.031
cell motilityGO:00488702440.031
regulation of programmed cell deathGO:00430671010.031
lipid metabolic processGO:0006629520.030
secondary metabolic processGO:001974830.030
positive regulation of nucleobase containing compound metabolic processGO:0045935690.030
intracellular receptor signaling pathwayGO:0030522300.030
regulation of multicellular organismal developmentGO:20000262230.030
retina development in camera type eyeGO:00600411460.029
mesoderm developmentGO:0007498880.029
regulation of anatomical structure morphogenesisGO:00226031300.029
epithelial cell morphogenesisGO:000338220.029
cellular response to organic substanceGO:00713101050.029
organic acid metabolic processGO:0006082310.029
endothelial cell developmentGO:0001885120.028
endodermal cell differentiationGO:0035987190.028
regulation of immune responseGO:0050776140.027
response to other organismGO:0051707970.027
determination of left right symmetryGO:00073681790.027
determination of heart left right asymmetryGO:00613711170.027
developmental growthGO:00485891660.027
Mouse
response to uvGO:000941130.027
circulatory system processGO:0003013870.026
chordate embryonic developmentGO:00430092710.026
negative regulation of map kinase activityGO:004340720.026
nephron epithelium morphogenesisGO:007208810.026
positive regulation of rna metabolic processGO:0051254590.026
positive regulation of signal transductionGO:0009967560.026
phosphorus metabolic processGO:00067931090.026
regulation of cell differentiationGO:00455951420.026
regulation of nervous system developmentGO:0051960900.026
striated muscle cell developmentGO:00550021080.026
regulation of behaviorGO:0050795240.026
positive regulation of cell cycleGO:004578730.026
carboxylic acid metabolic processGO:0019752220.025
lateral line system developmentGO:0048925760.025
erythrocyte developmentGO:0048821240.025
nuclear transportGO:005116940.025
sequestering of calcium ionGO:005120830.025
formation of primary germ layerGO:0001704620.025
sensory organ developmentGO:00074233930.025
positive regulation of signalingGO:0023056560.025
regulation of purine nucleotide biosynthetic processGO:1900371150.025
positive regulation of metabolic processGO:00098931080.025
dorsal ventral pattern formationGO:00099531250.025
negative regulation of behaviorGO:004852160.025
intracellular signal transductionGO:0035556850.024
pronephros developmentGO:0048793690.024
regulation of blood pressureGO:000821710.024
generation of neuronsGO:00486993850.024
sensory system developmentGO:0048880760.024
morphogenesis of an epithelial sheetGO:0002011490.024
cellular homeostasisGO:0019725260.023
head developmentGO:00603223030.023
renal tubule morphogenesisGO:006133310.023
lateral line developmentGO:0048882660.023
negative regulation of cyclase activityGO:003128060.023
response to corticosteroidGO:003196010.023
water homeostasisGO:003010440.023
regulation of cell deathGO:00109411030.023
central nervous system developmentGO:00074173870.022
response to organic cyclic compoundGO:0014070510.022
positive regulation of cellular amino acid metabolic processGO:004576400.022
urogenital system developmentGO:0001655970.022
regulation of blood circulationGO:1903522320.022
embryonic skeletal system morphogenesisGO:0048704930.022
lipid storageGO:001991510.022
positive regulation of non canonical wnt signaling pathwayGO:200005230.022
negative regulation of protein transportGO:005122430.022
positive regulation of camp biosynthetic processGO:003081920.022
cyclic purine nucleotide metabolic processGO:0052652180.021
regulation of molecular functionGO:0065009700.021
response to alkaloidGO:004327920.021
positive regulation of biological processGO:00485182530.021
Mouse
developmental maturationGO:0021700340.021
ovarian follicle developmentGO:000154120.021
oxoacid metabolic processGO:0043436310.021
endoderm formationGO:0001706290.021
eye morphogenesisGO:00485921440.021
positive regulation of biosynthetic processGO:0009891680.021
carbohydrate homeostasisGO:003350010.021
signal transduction in absence of ligandGO:003803410.021
single organism biosynthetic processGO:0044711710.020
actomyosin structure organizationGO:0031032530.020
sodium ion transportGO:0006814240.020
cell surface receptor signaling pathwayGO:00071663250.020
purine containing compound metabolic processGO:0072521290.020
regulation of cell activationGO:005086510.020
macromolecule modificationGO:00434121110.019
regulation of organ growthGO:004662030.019
Mouse
regulation of catalytic activityGO:0050790550.019
negative regulation of phosphate metabolic processGO:0045936130.019
negative regulation of adenylate cyclase activityGO:000719460.019
response to ketoneGO:190165410.019
tissue remodelingGO:004877140.019
cellular response to chemical stimulusGO:00708871570.019
ear developmentGO:00435831270.018
negative regulation of cellular metabolic processGO:0031324770.018
ameboidal type cell migrationGO:00016671430.018
retina morphogenesis in camera type eyeGO:0060042790.018
ketone biosynthetic processGO:004218120.018
programmed cell deathGO:00125011190.018
blood vessel developmentGO:00015682460.018
myeloid cell differentiationGO:0030099860.018
determination of bilateral symmetryGO:00098552040.018
positive regulation of transcription dna templatedGO:0045893570.018
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.018
hatchingGO:003518840.018
negative regulation of cell developmentGO:0010721260.018
nucleotide biosynthetic processGO:0009165210.018
negative regulation of metabolic processGO:0009892860.018
lymphocyte proliferationGO:004665110.017
Mouse
single organism behaviorGO:0044708240.017
ribose phosphate biosynthetic processGO:0046390200.017
response to organic substanceGO:00100331530.017
regulation of anatomical structure sizeGO:0090066330.017
embryonic skeletal system developmentGO:0048706970.017
negative regulation of cellular biosynthetic processGO:0031327550.017
cellular protein metabolic processGO:00442671290.017
protein localization to nucleusGO:003450430.017
cellular protein catabolic processGO:004425740.017
b cell activationGO:004211320.017
Mouse
motor neuron axon guidanceGO:0008045230.017
positive regulation of cell divisionGO:005178120.017
cation homeostasisGO:0055080330.017
cellular response to retinoic acidGO:007130010.017
dorsal aorta developmentGO:003590740.016
regulation of apoptotic processGO:0042981980.016
regulation of gene expressionGO:00104682650.016
Mouse
positive regulation of macromolecule biosynthetic processGO:0010557590.016
phagocytosisGO:000690930.016
peptide transportGO:001583310.016
leukocyte homeostasisGO:000177620.016
cellular response to external stimulusGO:007149620.016
aorta morphogenesisGO:003590930.016
regulation of adenylate cyclase activityGO:004576160.016
negative regulation of endopeptidase activityGO:0010951100.016
deathGO:00162651210.016
striated muscle tissue developmentGO:00147061100.016
glomerular epithelial cell fate commitmentGO:007231440.016
neuron developmentGO:00486662620.016
positive regulation of muscle organ developmentGO:004863610.016
regulation of cysteine type endopeptidase activityGO:2000116210.015
response to external biotic stimulusGO:0043207970.015
positive regulation of cytokine productionGO:000181920.015
internal protein amino acid acetylationGO:000647520.015
heart developmentGO:00075073130.015
regenerationGO:0031099910.015
neuron projection guidanceGO:0097485860.015
regulation of peptidyl tyrosine phosphorylationGO:005073010.015
negative regulation of catalytic activityGO:0043086210.015
negative regulation of purine nucleotide metabolic processGO:190054370.015
positive regulation of cellular amine metabolic processGO:003324000.015
regulation of system processGO:0044057400.015
regulation of purine nucleotide metabolic processGO:1900542170.015
alcohol biosynthetic processGO:004616520.015
spermatid differentiationGO:004851520.015
regulation of lyase activityGO:0051339120.015
positive regulation of immune responseGO:0050778110.015
i kappab kinase nf kappab signalingGO:000724940.015
chondrocyte intercalation involved in growth plate cartilage morphogenesisGO:000342810.015
taxisGO:00423301090.015
negative regulation of secretionGO:005104820.015
cell proliferationGO:0008283800.015
Mouse
neuroblast proliferationGO:000740520.015
stem cell developmentGO:0048864820.015
nephron developmentGO:0072006310.014
regulation of protein phosphorylationGO:0001932180.014
multicellular organismal signalingGO:0035637220.014
regulation of phosphorus metabolic processGO:0051174430.014
cell activationGO:0001775160.014
Mouse
purine nucleotide metabolic processGO:0006163270.014
developmental cell growthGO:0048588520.014
negative regulation of camp biosynthetic processGO:003081870.014
proteolysisGO:0006508380.014
negative regulation of nucleobase containing compound metabolic processGO:0045934590.014
positive regulation of cellular processGO:00485222010.014
ubiquitin dependent protein catabolic processGO:000651130.014
embryonic cranial skeleton morphogenesisGO:0048701900.014
apoptotic processGO:00069151160.014
response to drugGO:004249330.014
aorta developmentGO:003590440.014
artery developmentGO:0060840220.014
protein modification processGO:00362111000.014
negative regulation of homeostatic processGO:003284550.014
positive regulation of neural precursor cell proliferationGO:200017910.014
regulation of circadian rhythmGO:004275240.014
camp biosynthetic processGO:0006171110.014
positive regulation of interferon beta productionGO:003272810.013
calcium ion transport into cytosolGO:006040230.013
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.013
spermatid developmentGO:000728620.013
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:000718750.013
heart contractionGO:0060047710.013
embryonic heart tube developmentGO:00350501330.013
negative regulation of phosphorus metabolic processGO:0010563130.013
positive regulation of carbohydrate metabolic processGO:004591310.013
regulation of cellular macromolecule biosynthetic processGO:20001122220.013
negative regulation of oocyte developmentGO:006028320.013
negative regulation of cysteine type endopeptidase activityGO:200011780.013
regulation of leukocyte differentiationGO:190210550.013
somitogenesisGO:0001756870.013
germ cell developmentGO:0007281220.013
forebrain developmentGO:0030900960.013
organ growthGO:0035265120.013
Mouse
regulation of cell developmentGO:00602841000.013
organism emergence from protective structureGO:007168440.013
regulation of protein complex assemblyGO:004325430.013
metal ion homeostasisGO:0055065260.013
blood vessel morphogenesisGO:00485142160.013
regulation of receptor activityGO:001046920.013
cellular component assemblyGO:00226071700.013
homeostasis of number of cellsGO:0048872620.013
extrinsic apoptotic signaling pathwayGO:009719130.012
regulation of tube sizeGO:003515020.012
actin filament based processGO:0030029640.012
regulation of establishment of protein localizationGO:007020140.012
response to glucocorticoidGO:005138410.012
transmission of nerve impulseGO:0019226190.012
developmental process involved in reproductionGO:0003006270.012
regulation of defense response to virus by hostGO:005069110.012
hindbrain developmentGO:0030902910.012
cation transportGO:0006812810.012
single organism organelle organizationGO:19025891990.012
positive regulation of cellular component biogenesisGO:004408930.012
tissue regenerationGO:0042246740.012
response to estrogenGO:0043627270.012
leukocyte activationGO:0045321120.012
Mouse
cellular component assembly involved in morphogenesisGO:00109271070.012
cytokinesisGO:000091030.012
regulation of cytoplasmic transportGO:190364940.012
regulation of phosphate metabolic processGO:0019220430.012
regulation of neurogenesisGO:0050767870.012
cellular component morphogenesisGO:00329893360.012
positive regulation of cell differentiationGO:0045597300.012
protein metabolic processGO:00195381830.012
modification dependent macromolecule catabolic processGO:004363230.012
alcohol metabolic processGO:0006066110.012
vasculature developmentGO:00019442780.012
regulation of peptidase activityGO:0052547230.012
adult behaviorGO:003053420.012
endodermal cell fate specificationGO:0001714170.012
meiotic nuclear divisionGO:000712640.012
proteolysis involved in cellular protein catabolic processGO:005160330.011
cell maturationGO:0048469230.011
chemical homeostasisGO:0048878490.011
t cell activationGO:004211060.011
Mouse
negative regulation of reproductive processGO:200024230.011
regulation of developmental growthGO:0048638380.011
Mouse
regulation of inflammatory responseGO:005072720.011
negative regulation of multi organism processGO:004390130.011
defense responseGO:0006952470.011
regulation of proteolysisGO:0030162240.011
negative regulation of programmed cell deathGO:0043069580.011
response to biotic stimulusGO:0009607970.011
regulation of sequestering of calcium ionGO:005128240.011
regulation of dna templated transcription elongationGO:003278430.011
regulation of cellular amino acid metabolic processGO:000652100.011
skeletal system morphogenesisGO:00487051020.011
response to steroid hormoneGO:0048545350.011
neural precursor cell proliferationGO:0061351200.011
negative regulation of lyase activityGO:005135060.011
feeding behaviorGO:000763150.011
heart processGO:0003015710.011
establishment of localizationGO:00512342440.011
regulation of protein metabolic processGO:0051246560.011
activation of mapk activityGO:000018730.011
positive regulation of cell activationGO:005086710.011
regulation of blood vessel sizeGO:005088020.011
embryonic organ morphogenesisGO:00485622740.011
negative regulation of signalingGO:0023057960.011
innervationGO:006038430.011
astrocyte differentiationGO:004870810.010
positive regulation of rna biosynthetic processGO:1902680570.010
transcription elongation from rna polymerase ii promoterGO:000636830.010
response to topologically incorrect proteinGO:003596620.010
regulation of gastrulationGO:0010470240.010
regulation of cellular protein metabolic processGO:0032268520.010
positive regulation of macromolecule metabolic processGO:0010604930.010
apoptotic signaling pathwayGO:0097190230.010
left right pattern formationGO:0060972190.010

rag2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.038
musculoskeletal system diseaseDOID:1700.016
osteochondrodysplasiaDOID:225600.016
bone diseaseDOID:008000100.016
connective tissue diseaseDOID:6500.016
bone development diseaseDOID:008000600.016
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.013
nervous system diseaseDOID:86300.011