Danio rerio

0 known processes

eif4a1a

eukaryotic translation initiation factor 4A, isoform 1A

(Aliases: wu:fb20a10,wu:fc96c01,wu:fc76a02,fb49a04,wu:fd15g03,im:7143023,wu:fb49a04,eif4a1)

eif4a1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
gene expressionGO:00104672520.726
larval developmentGO:000216420.633
organic cyclic compound metabolic processGO:19013603010.575
regulation of gene expressionGO:00104682650.505
regulation of mrna processingGO:005068430.470
cellular biosynthetic processGO:00442492860.462
cellular macromolecule metabolic processGO:00442603910.390
macromolecule biosynthetic processGO:00090592270.384
rna processingGO:0006396250.355
translational initiationGO:000641330.347
regulation of macromolecule metabolic processGO:00602553170.309
cellular aromatic compound metabolic processGO:00067252950.283
pole plasm assemblyGO:000731540.268
organic substance biosynthetic processGO:19015762890.244
nitrogen compound metabolic processGO:00068073190.244
regulation of metabolic processGO:00192223590.242
protein polyubiquitinationGO:000020940.242
atp catabolic processGO:000620040.236
embryo development ending in birth or egg hatchingGO:00097922710.230
cellular nitrogen compound metabolic processGO:00346412900.228
response to chemicalGO:00422213200.224
cellular component biogenesisGO:00440851780.222
regulation of translational initiationGO:000644610.220
regulation of biosynthetic processGO:00098892500.219
locomotionGO:00400113130.218
regulation of cellular biosynthetic processGO:00313262450.215
cellular nitrogen compound biosynthetic processGO:00442712180.200
negative regulation of cellular processGO:00485232830.184
nucleic acid metabolic processGO:00903042440.171
nucleobase containing compound biosynthetic processGO:00346542050.171
response to external stimulusGO:00096052640.165
regulation of nitrogen compound metabolic processGO:00511712510.164
agingGO:000756820.164
mrna stabilizationGO:004825540.160
nucleobase containing compound metabolic processGO:00061392740.159
regulation of protein metabolic processGO:0051246560.156
positive regulation of cellular processGO:00485222010.149
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377100.148
positive regulation of transportGO:005105020.147
establishment of localizationGO:00512342440.147
regulation of mrna splicing via spliceosomeGO:004802430.144
rna splicingGO:0008380160.142
tube morphogenesisGO:00352393490.138
rna stabilizationGO:004348940.138
regulation of multicellular organismal processGO:00512392770.134
negative regulation of biological processGO:00485193040.134
biosynthetic processGO:00090582940.133
heterocycle metabolic processGO:00464832900.133
3 utr mediated mrna stabilizationGO:007093530.124
positive regulation of biosynthetic processGO:0009891680.121
intracellular transportGO:0046907320.121
ion transmembrane transportGO:0034220910.119
oocyte anterior posterior axis specificationGO:000731440.118
regulation of cellular metabolic processGO:00313233200.117
regulation of rna metabolic processGO:00512522240.109
ribonucleoprotein complex biogenesisGO:0022613130.106
cell surface receptor signaling pathwayGO:00071663250.103
rna transportGO:005065820.103
interaction with hostGO:005170140.103
microtubule organizing center organizationGO:003102310.101
single organism metabolic processGO:00447102170.100
neurotransmitter transportGO:000683620.098
eye developmentGO:00016542770.097
transportGO:00068102200.097
cellular macromolecule biosynthetic processGO:00346452240.096
cellular response to topologically incorrect proteinGO:003596720.095
organelle assemblyGO:00709251100.095
rna localizationGO:000640340.093
single organism reproductive processGO:0044702400.092
oocyte maturationGO:000155640.092
immune system processGO:00023762410.090
transmembrane transportGO:00550851200.090
purine nucleoside monophosphate catabolic processGO:000912840.088
nuclear exportGO:005116810.087
ion transportGO:00068111140.081
purine ribonucleoside monophosphate catabolic processGO:000916940.080
reproductionGO:0000003400.079
heterocycle biosynthetic processGO:00181302150.079
protein complex disassemblyGO:004324110.078
digestive tract developmentGO:00485652650.077
regulation of alternative mrna splicing via spliceosomeGO:000038110.076
cell migrationGO:00164772370.076
cell deathGO:00082191210.076
sensory organ developmentGO:00074233930.075
cellular component morphogenesisGO:00329893360.074
single organism localizationGO:19025782250.074
immune system developmentGO:00025201910.073
rna metabolic processGO:00160702190.073
aromatic compound biosynthetic processGO:00194382170.071
apoptotic processGO:00069151160.071
generation of neuronsGO:00486993850.070
muscle structure developmentGO:00610611960.069
regulation of biological qualityGO:00650082630.069
rna export from nucleusGO:000640510.068
single organism transportGO:00447652060.066
organelle organizationGO:00069962270.065
negative regulation of macromolecule biosynthetic processGO:0010558480.065
phagocytosisGO:000690930.064
cell motilityGO:00488702440.064
nucleocytoplasmic transportGO:000691340.064
neuron differentiationGO:00301823530.064
chemotaxisGO:00069351040.063
regulation of cellular macromolecule biosynthetic processGO:20001122220.063
digestive tract morphogenesisGO:00485462310.063
single organism intracellular transportGO:1902582250.063
negative regulation of rna splicingGO:003311910.062
ribosomal small subunit biogenesisGO:004227420.062
head developmentGO:00603223030.061
regulation of cell deathGO:00109411030.060
morphogenesis of an epitheliumGO:00020093330.060
localization of cellGO:00516742440.060
blood vessel developmentGO:00015682460.059
spermatid developmentGO:000728620.058
regulation of intracellular protein transportGO:003315730.057
deathGO:00162651210.056
regulation of mrna stabilityGO:004348840.056
skeletal muscle organ developmentGO:0060538780.055
cellular response to dsrnaGO:007135910.054
establishment of rna localizationGO:005123630.054
fertilizationGO:000956630.054
guanosine containing compound catabolic processGO:190106920.053
regulation of cytoplasmic transportGO:190364940.053
oocyte developmentGO:0048599140.053
protein metabolic processGO:00195381830.053
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018440.053
macromolecular complex subunit organizationGO:0043933740.052
cellular component movementGO:00069283350.052
maintenance of locationGO:005123540.051
ribonucleoside monophosphate catabolic processGO:000915840.051
neurotransmitter secretionGO:000726920.050
macromolecular complex disassemblyGO:003298410.050
regulation of apoptotic processGO:0042981980.050
regulation of cytokine productionGO:000181730.050
cellular response to chemical stimulusGO:00708871570.050
regulation of tube sizeGO:003515020.049
positive regulation of biological processGO:00485182530.049
negative regulation of metabolic processGO:0009892860.048
regulation of developmental processGO:00507932470.048
growthGO:00400071740.048
cellular protein metabolic processGO:00442671290.047
response to organic substanceGO:00100331530.047
programmed cell deathGO:00125011190.046
establishment of localization in cellGO:0051649770.046
muscle cell developmentGO:00550011150.046
positive regulation of cellular metabolic processGO:0031325940.046
transcription dna templatedGO:00063511810.046
lipid storageGO:001991510.046
regulation of reproductive processGO:200024140.045
spermatid differentiationGO:004851520.045
vasculature developmentGO:00019442780.045
mrna processingGO:0006397140.044
protein polymerizationGO:005125840.044
stem cell maintenanceGO:001982740.044
negative regulation of signal transductionGO:0009968940.044
synaptic growth at neuromuscular junctionGO:005112420.043
cytoskeleton organizationGO:0007010960.043
hemopoiesisGO:00300971830.043
response to stressGO:00069502630.042
regulation of stem cell differentiationGO:200073640.042
regulation of neurotransmitter transportGO:005158810.042
brain developmentGO:00074202930.042
establishment of protein localization to organelleGO:007259440.042
response to coldGO:000940940.042
negative regulation of cellular metabolic processGO:0031324770.042
positive regulation of macromolecule biosynthetic processGO:0010557590.041
single organism cellular localizationGO:1902580460.041
regulation of transcription dna templatedGO:00063552130.041
regulation of extrinsic apoptotic signaling pathwayGO:200123630.041
inorganic ion transmembrane transportGO:0098660570.041
ribonucleoprotein complex assemblyGO:002261850.040
camera type eye developmentGO:00430102220.040
cellular response to unfolded proteinGO:003462020.039
meiotic nuclear divisionGO:000712640.039
positive regulation of cytosolic calcium ion concentrationGO:000720440.039
response to uvGO:000941130.039
cell part morphogenesisGO:00329902460.038
response to topologically incorrect proteinGO:003596620.038
cellular response to external stimulusGO:007149620.038
cellular amino acid metabolic processGO:000652070.038
regulation of multicellular organismal developmentGO:20000262230.038
protein complex subunit organizationGO:0071822460.038
female sex differentiationGO:004666040.037
nucleoside monophosphate catabolic processGO:000912540.037
multi organism processGO:00517041340.037
protein importGO:001703830.037
alternative mrna splicing via spliceosomeGO:000038010.037
hematopoietic or lymphoid organ developmentGO:00485341910.037
covalent chromatin modificationGO:0016569200.037
translationGO:000641250.037
positive regulation of cell cycleGO:004578730.037
cytoplasm organizationGO:000702840.036
oxoacid metabolic processGO:0043436310.036
cellular component assemblyGO:00226071700.036
cell projection morphogenesisGO:00488582440.035
striated muscle tissue developmentGO:00147061100.035
regulation of primary metabolic processGO:00800903110.034
heart developmentGO:00075073130.034
oocyte differentiationGO:0009994140.034
regulation of protein ubiquitinationGO:003139630.033
regulation of nucleobase containing compound metabolic processGO:00192192500.033
developmental process involved in reproductionGO:0003006270.033
cellular localizationGO:0051641970.033
protein localizationGO:0008104400.033
organic cyclic compound biosynthetic processGO:19013622230.033
regulation of nucleocytoplasmic transportGO:004682220.033
small molecule metabolic processGO:0044281770.033
guanosine containing compound metabolic processGO:190106840.032
sexual reproductionGO:0019953360.032
single fertilizationGO:000733830.032
reproductive processGO:0022414400.032
metal ion transportGO:0030001580.031
embryonic heart tube developmentGO:00350501330.031
regulation of response to stimulusGO:00485832690.031
posttranscriptional regulation of gene expressionGO:0010608140.031
positive regulation of cytokine productionGO:000181920.031
ameboidal type cell migrationGO:00016671430.031
rna splicing via transesterification reactionsGO:0000375100.031
negative regulation of cellular biosynthetic processGO:0031327550.031
single organism organelle organizationGO:19025891990.030
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.030
inorganic cation transmembrane transportGO:0098662500.030
regulation of circadian rhythmGO:004275240.030
gtp metabolic processGO:004603940.030
cellular amine metabolic processGO:004410620.029
multicellular organism growthGO:003526440.029
organic acid metabolic processGO:0006082310.029
phosphate containing compound metabolic processGO:00067961080.029
angiogenesisGO:00015251580.029
tissue remodelingGO:004877140.029
regulation of cellular component organizationGO:0051128860.029
microtubule based processGO:0007017600.029
skeletal muscle tissue developmentGO:0007519670.029
amine metabolic processGO:000930820.028
gene silencing by rnaGO:003104740.028
positive regulation of gene expressionGO:0010628710.028
muscle tissue developmentGO:00605371100.028
specification of symmetryGO:00097992040.028
regulation of macromolecule biosynthetic processGO:00105562250.028
striated muscle cell differentiationGO:00511461290.028
negative regulation of cytokine productionGO:000181810.028
negative regulation of cell deathGO:0060548600.028
digestive system developmentGO:00551232890.027
negative regulation of apoptotic processGO:0043066550.027
heart contractionGO:0060047710.027
regenerationGO:0031099910.027
positive regulation of translationGO:004572710.027
developmental maturationGO:0021700340.027
regulation of bindingGO:005109830.027
mrna metabolic processGO:0016071200.027
macromolecule methylationGO:0043414190.026
cytoskeleton dependent cytokinesisGO:006164030.026
apoptotic process involved in developmentGO:190274220.026
positive regulation of cellular component biogenesisGO:004408930.026
cell substrate adhesionGO:003158940.026
negative regulation of gene expressionGO:0010629650.026
regulation of programmed cell deathGO:00430671010.025
response to woundingGO:00096111160.025
protein targeting to membraneGO:000661210.025
nucleic acid templated transcriptionGO:00976591810.025
positive regulation of cellular biosynthetic processGO:0031328680.025
heart loopingGO:0001947940.025
carboxylic acid metabolic processGO:0019752220.025
response to biotic stimulusGO:0009607970.025
ion homeostasisGO:0050801410.025
cellular protein catabolic processGO:004425740.024
wound healingGO:0042060900.024
cellular macromolecular complex assemblyGO:0034622240.024
germ cell developmentGO:0007281220.024
regulation of rna splicingGO:004348480.024
regulation of cell shapeGO:000836010.024
cellular response to extracellular stimulusGO:003166820.024
positive regulation of protein metabolic processGO:0051247230.024
embryonic heart tube morphogenesisGO:00031431080.023
response to abiotic stimulusGO:00096281220.023
nucleobase containing small molecule metabolic processGO:0055086320.023
response to lipidGO:0033993600.023
endoplasmic reticulum unfolded protein responseGO:003096820.023
regulation of rna biosynthetic processGO:20011412130.022
signal transductionGO:00071654550.022
negative regulation of programmed cell deathGO:0043069580.022
regulation of localizationGO:00328791040.022
modification dependent macromolecule catabolic processGO:004363230.022
regulation of translationGO:000641730.022
protein methylationGO:0006479130.022
regulation of fatty acid metabolic processGO:001921710.022
regulation of metal ion transportGO:001095940.022
nucleic acid transportGO:005065720.022
macromolecule localizationGO:0033036540.021
nuclear transportGO:005116940.021
positive regulation of metabolic processGO:00098931080.021
muscle cell differentiationGO:00426921390.021
proteolysisGO:0006508380.021
regulation of cell activationGO:005086510.021
axon developmentGO:00615641660.021
organonitrogen compound biosynthetic processGO:1901566470.021
regulation of signalingGO:00230512350.021
negative regulation of synapse assemblyGO:005196420.021
nucleoside phosphate metabolic processGO:0006753280.021
protein complex assemblyGO:0006461300.021
negative regulation of rna biosynthetic processGO:1902679450.021
negative regulation of translationGO:001714810.020
cation transmembrane transportGO:0098655650.020
purine containing compound metabolic processGO:0072521290.020
cellular ketone metabolic processGO:0042180110.020
cellular response to organic substanceGO:00713101050.020
modification dependent protein catabolic processGO:001994130.020
cell projection organizationGO:00300302840.020
regulation of signal transductionGO:00099662250.020
organic substance transportGO:0071702580.020
cellular protein localizationGO:0034613200.020
regulation of protein transportGO:005122330.020
regulation of gtp catabolic processGO:003312420.020
purine ribonucleotide metabolic processGO:0009150270.019
regulation of cellular amino acid metabolic processGO:000652100.019
striated muscle cell developmentGO:00550021080.019
maternal determination of anterior posterior axis embryoGO:000835840.019
negative regulation of cell communicationGO:0010648960.019
actin polymerization or depolymerizationGO:000815420.019
ubiquitin dependent protein catabolic processGO:000651130.019
organonitrogen compound metabolic processGO:1901564740.019
dorsal ventral pattern formationGO:00099531250.019
regulation of cellular protein metabolic processGO:0032268520.018
gtp catabolic processGO:000618420.018
positive regulation of striated muscle tissue developmentGO:004584410.018
regulation of cell communicationGO:00106462320.018
mononuclear cell proliferationGO:003294310.018
regulation of cellular amine metabolic processGO:003323800.018
rhythmic processGO:0048511210.018
internal protein amino acid acetylationGO:000647520.018
alpha amino acid metabolic processGO:190160530.018
vesicle mediated transportGO:0016192220.018
regulation of cellular ketone metabolic processGO:001056570.018
response to corticosteroidGO:003196010.018
cellular component disassemblyGO:002241110.018
regulation of mitotic cell cycleGO:0007346250.018
circulatory system processGO:0003013870.018
regionalizationGO:00030022740.018
negative regulation of reproductive processGO:200024230.017
toll like receptor signaling pathwayGO:000222440.017
response to temperature stimulusGO:0009266150.017
urogenital system developmentGO:0001655970.017
negative regulation of nitrogen compound metabolic processGO:0051172590.017
blood vessel morphogenesisGO:00485142160.017
retina development in camera type eyeGO:00600411460.017
determination of left right symmetryGO:00073681790.017
male meiosisGO:000714020.017
response to light stimulusGO:0009416460.017
post embryonic organ morphogenesisGO:004856310.017
mitochondrial transportGO:000683920.017
cellular protein complex disassemblyGO:004362410.017
positive regulation of cellular catabolic processGO:003133130.017
protein dephosphorylationGO:000647030.017
regulation of calcium ion transportGO:005192420.017
determination of heart left right asymmetryGO:00613711170.017
regulation of myelinationGO:003164110.017
metal ion homeostasisGO:0055065260.017
regulation of purine nucleotide catabolic processGO:003312120.016
kidney developmentGO:0001822920.016
negative regulation of signalingGO:0023057960.016
microtubule cytoskeleton organizationGO:0000226330.016
negative regulation of macromolecule metabolic processGO:0010605760.016
adult behaviorGO:003053420.016
centrosome organizationGO:005129710.016
cellular response to starvationGO:000926710.016
protein homooligomerizationGO:005126030.016
cation transportGO:0006812810.016
regulation of molecular functionGO:0065009700.016
fin regenerationGO:0031101510.016
spermatogenesisGO:000728370.016
determination of bilateral symmetryGO:00098552040.016
stem cell divisionGO:001714510.016
oogenesisGO:0048477140.016
regulation of protein complex assemblyGO:004325430.016
mitochondrion organizationGO:000700540.016
macromolecular complex assemblyGO:0065003350.016
gastrulationGO:00073692080.016
response to glucocorticoidGO:005138410.016
energy reserve metabolic processGO:000611220.016
intrinsic apoptotic signaling pathway by p53 class mediatorGO:007233290.016
calcium ion importGO:007050940.016
zymogen activationGO:003163830.015
post embryonic organ developmentGO:004856940.015
negative regulation of multicellular organismal processGO:0051241690.015
axon guidanceGO:0007411860.015
intrinsic apoptotic signaling pathwayGO:0097193200.015
regulation of skeletal muscle tissue developmentGO:004864140.015
b cell activationGO:004211320.015
regulation of cell differentiationGO:00455951420.015
somitogenesisGO:0001756870.015
cellular response to retinoic acidGO:007130010.015
regulation of synapse organizationGO:005080730.015
regulation of cellular carbohydrate metabolic processGO:001067540.015
heart processGO:0003015710.015
multicellular organism reproductionGO:0032504350.015
segmentationGO:0035282970.015
homeostatic processGO:00425921420.015
regulation of nucleotide catabolic processGO:003081120.015
intracellular mrna localizationGO:000829810.015
pronuclear migrationGO:003504610.015
muscle organ developmentGO:00075171010.015
posttranscriptional gene silencing by rnaGO:003519430.015
protein acetylationGO:000647320.015
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.015
neuron projection morphogenesisGO:00488121610.015
cellular response to stressGO:0033554620.015
cellular protein complex assemblyGO:0043623190.015
calcium mediated signalingGO:001972220.015
cellular response to molecule of bacterial originGO:007121930.015
b cell differentiationGO:003018310.014
cell cycleGO:0007049930.014
positive regulation of cytoskeleton organizationGO:005149530.014
tissue regenerationGO:0042246740.014
phosphorus metabolic processGO:00067931090.014
ribosome biogenesisGO:004225490.014
production of mirnas involved in gene silencing by mirnaGO:003519610.014
development of primary female sexual characteristicsGO:004654540.014
regulation of establishment of protein localizationGO:007020140.014
leukocyte proliferationGO:007066110.014
carbohydrate derivative metabolic processGO:1901135610.014
taxisGO:00423301090.014
nucleotide metabolic processGO:0009117280.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
forebrain developmentGO:0030900960.014
innate immune response activating signal transductionGO:000275850.014
calcium ion homeostasisGO:0055074190.014
regulation of carbohydrate metabolic processGO:000610940.013
cranial nerve developmentGO:0021545420.013
protein alkylationGO:0008213130.013
epithelial cell differentiationGO:00308551160.013
lymphocyte proliferationGO:004665110.013
regulation of canonical wnt signaling pathwayGO:0060828340.013
positive regulation of carbohydrate metabolic processGO:004591310.013
developmental growthGO:00485891660.013
type i interferon productionGO:003260620.013
gene silencingGO:001645840.013
cell morphogenesisGO:00009022890.013
positive regulation of apoptotic signaling pathwayGO:200123510.013
regulation of hydrolase activityGO:0051336280.013
enzyme linked receptor protein signaling pathwayGO:00071671060.013
regulation of protein complex disassemblyGO:004324410.013
posttranscriptional gene silencingGO:001644130.013
regulation of synapse assemblyGO:005196330.013
calcium ion transmembrane transportGO:0070588130.013
embryonic organ morphogenesisGO:00485622740.013
positive regulation of secretionGO:005104710.013
membrane organizationGO:0061024210.013
embryonic limb morphogenesisGO:003032620.013
epithelial tube morphogenesisGO:00605621480.013
regulation of transportGO:0051049450.013
symbiosis encompassing mutualism through parasitismGO:004440340.012
spliceosomal complex assemblyGO:000024510.012
positive regulation of mrna processingGO:005068510.012
regulation of nervous system developmentGO:0051960900.012
regulation of protein bindingGO:004339330.012
regulation of gene expression epigeneticGO:0040029110.012
cellular biogenic amine metabolic processGO:000657620.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
neuron developmentGO:00486662620.012
methylationGO:0032259220.012
female gonad developmentGO:000858540.012
peptidyl lysine acetylationGO:001839420.012
blood circulationGO:0008015870.012
rna biosynthetic processGO:00327741810.012
receptor mediated endocytosisGO:000689860.012
regulation of wnt signaling pathwayGO:0030111530.012
lipid metabolic processGO:0006629520.012
regulation of gtpase activityGO:004308720.012
cell morphogenesis involved in neuron differentiationGO:00486671630.012
cellular response to lipidGO:0071396390.011
embryonic organ developmentGO:00485683810.011
positive regulation of macromolecule metabolic processGO:0010604930.011
cellular response to nutrient levelsGO:003166920.011
membrane repolarizationGO:008600920.011
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.011
er nucleus signaling pathwayGO:000698420.011
regulation of nuclease activityGO:003206910.011
response to drugGO:004249330.011
meiotic chromosome segregationGO:004513230.011
positive regulation of muscle tissue developmentGO:190186310.011
positive regulation of purine nucleotide catabolic processGO:003312310.011
regulation of anatomical structure morphogenesisGO:00226031300.011
signal transduction by p53 class mediatorGO:0072331130.011
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.011
heart morphogenesisGO:00030071560.011
positive regulation of immune effector processGO:000269930.011
internal peptidyl lysine acetylationGO:001839320.011
mitotic cell cycle embryonicGO:004544820.011

eif4a1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.041
organ system cancerDOID:005068600.025
cancerDOID:16200.025
disease of metabolismDOID:001466700.023
disease of anatomical entityDOID:700.021
gastrointestinal system cancerDOID:311900.011
large intestine cancerDOID:567200.011
intestinal cancerDOID:1015500.011
colon cancerDOID:21900.011
colorectal cancerDOID:925600.011
colon carcinomaDOID:152000.011