Danio rerio

18 known processes

cd74

CD74 molecule, major histocompatibility complex, class II invariant chain

(Aliases: MGC158500,iclp2,MGC123161,zgc:123161,Iclp-2)

cd74 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular macromolecule metabolic processGO:00442603910.403
hematopoietic or lymphoid organ developmentGO:00485341910.274
sensory organ developmentGO:00074233930.204
immune system developmentGO:00025201910.197
regulation of cell communicationGO:00106462320.115
negative regulation of cellular processGO:00485232830.103
regulation of metabolic processGO:00192223590.102
modification dependent macromolecule catabolic processGO:004363230.084
regulation of protein transportGO:005122330.077
inner ear developmentGO:00488391260.076
regulation of multicellular organismal processGO:00512392770.076
multicellular organismal metabolic processGO:004423620.075
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.075
sensory system developmentGO:0048880760.074
positive regulation of muscle cell differentiationGO:005114910.073
ubiquitin dependent protein catabolic processGO:000651130.064
immune system processGO:00023762410.061
regulation of synapse organizationGO:005080730.060
regulation of signal transductionGO:00099662250.057
stem cell proliferationGO:007208940.054
agingGO:000756820.053
deathGO:00162651210.053
regulation of production of molecular mediator of immune responseGO:000270010.051
regionalizationGO:00030022740.049
regulation of multicellular organismal developmentGO:20000262230.048
proteasomal protein catabolic processGO:001049820.048
regulation of stem cell proliferationGO:007209120.047
b cell differentiationGO:003018310.047
heterocycle biosynthetic processGO:00181302150.046
cellular protein catabolic processGO:004425740.046
embryonic organ developmentGO:00485683810.045
regulation of programmed cell deathGO:00430671010.044
signal transductionGO:00071654550.043
regulation of macromolecule metabolic processGO:00602553170.042
nuclear transportGO:005116940.041
proteolysis involved in cellular protein catabolic processGO:005160330.040
leukocyte proliferationGO:007066110.040
response to chemicalGO:00422213200.040
actin polymerization or depolymerizationGO:000815420.040
heterocycle metabolic processGO:00464832900.040
lateral line developmentGO:0048882660.040
actin mediated cell contractionGO:007025210.039
cellular ketone metabolic processGO:0042180110.039
negative regulation of biological processGO:00485193040.039
regulation of cell shapeGO:000836010.039
positive regulation of transportGO:005105020.039
embryonic skeletal system morphogenesisGO:0048704930.038
regulation of cell deathGO:00109411030.038
vasculature developmentGO:00019442780.037
regulation of response to stimulusGO:00485832690.037
cell surface receptor signaling pathwayGO:00071663250.036
cell deathGO:00082191210.036
hemopoiesisGO:00300971830.035
gtp metabolic processGO:004603940.035
positive regulation of immune effector processGO:000269930.035
regulation of protein complex assemblyGO:004325430.034
cellular amine metabolic processGO:004410620.034
blood vessel morphogenesisGO:00485142160.033
biosynthetic processGO:00090582940.033
regulation of cell activationGO:005086510.033
protein secretionGO:000930610.033
negative regulation of protein phosphorylationGO:000193340.033
cellular nitrogen compound metabolic processGO:00346412900.033
blood vessel developmentGO:00015682460.032
immunoglobulin mediated immune responseGO:001606430.032
regulation of synapse assemblyGO:005196330.032
response to hexoseGO:000974630.031
cell motilityGO:00488702440.031
regulation of tube sizeGO:003515020.030
embryonic organ morphogenesisGO:00485622740.030
regulation of developmental processGO:00507932470.030
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.030
production of molecular mediator of immune responseGO:000244020.030
regulation of synaptic growth at neuromuscular junctionGO:000858210.030
single organism metabolic processGO:00447102170.030
chordate embryonic developmentGO:00430092710.029
programmed cell deathGO:00125011190.029
regulation of peptidyl tyrosine phosphorylationGO:005073010.028
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.028
somatic muscle developmentGO:000752540.028
b cell mediated immunityGO:001972430.028
i kappab kinase nf kappab signalingGO:000724940.027
positive regulation of secretionGO:005104710.027
b cell activationGO:004211320.027
actin filament based processGO:0030029640.027
positive regulation of map kinase activityGO:004340630.026
extrinsic apoptotic signaling pathwayGO:009719130.026
regulation of synaptic plasticityGO:004816710.026
centrosome organizationGO:005129710.026
amine metabolic processGO:000930820.026
collagen metabolic processGO:003296320.025
mononuclear cell proliferationGO:003294310.025
cellular nitrogen compound biosynthetic processGO:00442712180.025
homeostatic processGO:00425921420.025
regulation of primary metabolic processGO:00800903110.025
regulation of muscle contractionGO:000693730.025
response to external stimulusGO:00096052640.025
nucleobase containing compound metabolic processGO:00061392740.025
regulation of cellular amino acid metabolic processGO:000652100.025
regulation of nucleobase containing compound metabolic processGO:00192192500.024
regulation of extrinsic apoptotic signaling pathwayGO:200123630.024
spermatid developmentGO:000728620.024
cellular component morphogenesisGO:00329893360.024
regulation of cellular amine metabolic processGO:003323800.024
muscle organ developmentGO:00075171010.024
protein importGO:001703830.023
liver developmentGO:0001889960.023
retina morphogenesis in camera type eyeGO:0060042790.023
positive regulation of stress activated mapk cascadeGO:003287430.023
cellular aromatic compound metabolic processGO:00067252950.023
positive regulation of secretion by cellGO:190353210.023
single organism membrane fusionGO:004480120.022
angiogenesisGO:00015251580.022
protein import into nucleusGO:000660630.022
phagocytosisGO:000690930.022
skeletal muscle organ developmentGO:0060538780.022
rna metabolic processGO:00160702190.022
positive regulation of cellular processGO:00485222010.022
regulation of signalingGO:00230512350.022
positive regulation of notch signaling pathwayGO:004574730.022
aromatic compound biosynthetic processGO:00194382170.021
response to carbohydrateGO:000974330.021
negative regulation of protein kinase activityGO:000646940.021
nucleocytoplasmic transportGO:000691340.021
regulation of dna recombinationGO:000001820.021
organelle fusionGO:004828430.021
regulation of establishment of protein localizationGO:007020140.021
positive regulation of signalingGO:0023056560.021
negative regulation of programmed cell deathGO:0043069580.021
membrane fusionGO:006102520.021
regulation of nitrogen compound metabolic processGO:00511712510.021
positive regulation of catabolic processGO:000989640.021
neuron differentiationGO:00301823530.021
negative regulation of kinase activityGO:003367340.021
regulation of endocrine processGO:004406020.021
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.020
response to other organismGO:0051707970.020
intracellular signal transductionGO:0035556850.020
response to monosaccharideGO:003428430.020
locomotionGO:00400113130.020
somatic stem cell maintenanceGO:003501910.020
endosomal transportGO:001619720.020
protein metabolic processGO:00195381830.020
negative regulation of myeloid cell differentiationGO:004563810.020
cell activationGO:0001775160.020
skeletal system developmentGO:00015011810.020
microtubule organizing center organizationGO:003102310.020
regulation of stem cell differentiationGO:200073640.020
centrosome cycleGO:000709810.019
humoral immune response mediated by circulating immunoglobulinGO:000245530.019
peptidyl serine modificationGO:001820920.019
autophagyGO:000691440.019
cell migrationGO:00164772370.019
tissue remodelingGO:004877140.019
synaptic growth at neuromuscular junctionGO:005112420.019
cellular localizationGO:0051641970.019
positive regulation of response to stimulusGO:0048584800.019
regulation of cytoplasmic transportGO:190364940.019
nuclear importGO:005117030.019
negative regulation of synapse assemblyGO:005196420.019
axonal defasciculationGO:000741420.019
lymphocyte proliferationGO:004665110.019
regulation of striated muscle contractionGO:000694220.019
regulation of calcium ion transportGO:005192420.019
regulation of biological qualityGO:00650082630.019
negative regulation of cellular metabolic processGO:0031324770.019
leukocyte differentiationGO:0002521250.019
purine ribonucleoside monophosphate catabolic processGO:000916940.019
positive regulation of biological processGO:00485182530.018
response to abiotic stimulusGO:00096281220.018
positive regulation of cytoskeleton organizationGO:005149530.018
regulation of gene expressionGO:00104682650.018
sprouting angiogenesisGO:0002040530.018
response to organic substanceGO:00100331530.018
immune responseGO:0006955280.018
protein targeting to nucleusGO:004474430.018
oxoacid metabolic processGO:0043436310.018
regulation of multicellular organism growthGO:004001440.018
actin filament polymerizationGO:003004120.017
positive regulation of cytokine productionGO:000181920.017
cellular response to organic substanceGO:00713101050.017
positive regulation of muscle tissue developmentGO:190186310.017
cellular response to chemical stimulusGO:00708871570.017
transcription dna templatedGO:00063511810.017
cellular response to retinoic acidGO:007130010.017
muscle cell developmentGO:00550011150.017
sensory perception of chemical stimulusGO:000760630.017
regulation of organ growthGO:004662030.017
hatchingGO:003518840.017
camera type eye developmentGO:00430102220.017
tyrosine phosphorylation of stat proteinGO:000726010.017
nucleobase containing compound biosynthetic processGO:00346542050.017
positive regulation of cytosolic calcium ion concentrationGO:000720440.017
protein localization to nucleusGO:003450430.017
ribonucleoside monophosphate catabolic processGO:000915840.017
guanosine containing compound metabolic processGO:190106840.017
astrocyte differentiationGO:004870810.017
cell morphogenesisGO:00009022890.017
negative regulation of signal transductionGO:0009968940.017
viral processGO:001603210.017
t cell activationGO:004211060.016
organic cyclic compound biosynthetic processGO:19013622230.016
regulation of bindingGO:005109830.016
negative regulation of macromolecule metabolic processGO:0010605760.016
positive regulation of muscle organ developmentGO:004863610.016
localization of cellGO:00516742440.016
macromolecule modificationGO:00434121110.016
cellular component assembly involved in morphogenesisGO:00109271070.016
regulation of erythrocyte differentiationGO:004564620.016
regulation of skeletal muscle tissue developmentGO:004864140.016
macromolecular complex subunit organizationGO:0043933740.016
stem cell maintenanceGO:001982740.016
embryonic skeletal system developmentGO:0048706970.016
multicellular organism growthGO:003526440.016
gtp catabolic processGO:000618420.016
multi organism cellular processGO:004476420.016
regulation of cytokine productionGO:000181730.016
positive regulation of multicellular organismal processGO:0051240520.016
retina development in camera type eyeGO:00600411460.016
regulation of cellular ketone metabolic processGO:001056570.016
embryonic cranial skeleton morphogenesisGO:0048701900.016
cellular protein metabolic processGO:00442671290.016
positive regulation of cell activationGO:005086710.015
monocyte differentiationGO:003022420.015
negative regulation of response to stimulusGO:00485851040.015
erk1 and erk2 cascadeGO:007037140.015
striated muscle contractionGO:0006941120.015
positive regulation of striated muscle tissue developmentGO:004584410.015
muscle structure developmentGO:00610611960.015
establishment of protein localization to organelleGO:007259440.015
positive regulation of mesenchymal cell proliferationGO:000205310.015
developmental programmed cell deathGO:001062340.015
regulation of cell killingGO:003134120.015
positive regulation of cell cycleGO:004578730.015
regulation of purine nucleotide catabolic processGO:003312120.015
dorsal ventral pattern formationGO:00099531250.015
morphogenesis of an epitheliumGO:00020093330.015
positive regulation of cell killingGO:003134320.015
complement activationGO:000695630.015
regulation of cellular metabolic processGO:00313233200.015
regulation of nucleic acid templated transcriptionGO:19035062130.015
regulation of metal ion transportGO:001095940.015
ventricular cardiac muscle tissue developmentGO:000322930.015
single organism nuclear importGO:190259330.015
regulation of mrna processingGO:005068430.014
immunoglobulin productionGO:000237710.014
modification dependent protein catabolic processGO:001994130.014
lateral inhibitionGO:004633110.014
regulation of transmembrane transporter activityGO:002289820.014
larval developmentGO:000216420.014
cellular component disassemblyGO:002241110.014
response to drugGO:004249330.014
renal tubule morphogenesisGO:006133310.014
regulation of blood coagulationGO:003019310.014
positive regulation of protein polymerizationGO:003227320.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
regulation of nucleoside metabolic processGO:000911820.014
organic substance biosynthetic processGO:19015762890.014
negative regulation of immune responseGO:005077720.014
regulation of gtpase activityGO:004308720.014
negative regulation of leukocyte differentiationGO:190210610.014
digestive tract developmentGO:00485652650.014
smooth muscle contractionGO:000693920.014
regulation of glial cell differentiationGO:004568540.014
renal system process involved in regulation of systemic arterial blood pressureGO:000307110.014
regulation of ion transmembrane transporter activityGO:003241220.014
maintenance of locationGO:005123540.014
regulation of i kappab kinase nf kappab signalingGO:004312240.014
regulation of leukocyte mediated cytotoxicityGO:000191010.014
protein targeting to membraneGO:000661210.014
tissue migrationGO:0090130370.014
regulation of molecular functionGO:0065009700.014
regulation of cell differentiationGO:00455951420.013
regulation of blood vessel sizeGO:005088020.013
protein stabilizationGO:005082120.013
digestive system developmentGO:00551232890.013
protein polymerizationGO:005125840.013
interspecies interaction between organismsGO:004441940.013
response to glucoseGO:000974930.013
organic substance transportGO:0071702580.013
peptide transportGO:001583310.013
regulation of cardiac muscle contractionGO:005511720.013
apoptotic processGO:00069151160.013
regulation of myotube differentiationGO:001083020.013
cell substrate adhesionGO:003158940.013
regulation of locomotionGO:0040012550.013
regulation of transcription dna templatedGO:00063552130.013
positive regulation of nitrogen compound metabolic processGO:0051173690.013
muscle tissue developmentGO:00605371100.013
positive regulation of ras gtpase activityGO:003232010.013
negative regulation of nitrogen compound metabolic processGO:0051172590.013
homeostasis of number of cellsGO:0048872620.013
regulation of gtp catabolic processGO:003312420.013
exocytosisGO:000688710.013
cell matrix adhesionGO:000716040.013
establishment of localizationGO:00512342440.013
g1 s transition of mitotic cell cycleGO:000008210.013
regulation of apoptotic processGO:0042981980.013
protein dephosphorylationGO:000647030.013
positive regulation of cell differentiationGO:0045597300.013
regulation of rna metabolic processGO:00512522240.013
protein phosphorylationGO:0006468470.013
somite developmentGO:0061053960.013
calcium ion transport into cytosolGO:006040230.013
symbiosis encompassing mutualism through parasitismGO:004440340.013
embryonic digestive tract developmentGO:004856640.013
regulation of protein modification by small protein conjugation or removalGO:190332030.012
actin filament based movementGO:003004810.012
regulation of protein import into nucleusGO:004230620.012
generation of neuronsGO:00486993850.012
cell killingGO:000190620.012
regulation of nucleotide catabolic processGO:003081120.012
multicellular organismal macromolecule metabolic processGO:004425920.012
regulation of reactive oxygen species metabolic processGO:200037720.012
regulation of response to cytokine stimulusGO:006075930.012
response to biotic stimulusGO:0009607970.012
definitive hemopoiesisGO:0060216180.012
regulation of autophagyGO:001050630.012
cell cycle g1 s phase transitionGO:004484310.012
negative regulation of epithelial cell proliferationGO:005068010.012
organic acid metabolic processGO:0006082310.012
regulation of jak stat cascadeGO:004642530.012
regulation of hormone secretionGO:004688320.012
ion transportGO:00068111140.012
ameboidal type cell migrationGO:00016671430.012
positive regulation of programmed cell deathGO:0043068290.012
nucleoside monophosphate catabolic processGO:000912540.012
negative regulation of cytokine productionGO:000181810.012
protein complex disassemblyGO:004324110.012
muscle hypertrophyGO:001489620.012
positive regulation of neuron deathGO:190121610.012
convergent extensionGO:00600261180.012
macromolecular complex disassemblyGO:003298410.012
sensory perception of painGO:001923310.012
negative regulation of protein serine threonine kinase activityGO:007190120.012
immune effector processGO:0002252230.012
response to woundingGO:00096111160.012
cell agingGO:000756920.012
embryonic digestive tract morphogenesisGO:004855730.012
epithelium migrationGO:0090132250.012
epithelial cell morphogenesisGO:000338220.012
regulation of neuronal synaptic plasticityGO:004816810.012
negative regulation of mitosisGO:004583930.012
striated muscle cell developmentGO:00550021080.012
myeloid cell differentiationGO:0030099860.011
mitotic dna damage checkpointGO:004477340.011
response to topologically incorrect proteinGO:003596620.011
peptidyl lysine acetylationGO:001839420.011
carbohydrate homeostasisGO:003350010.011
somitogenesisGO:0001756870.011
regulation of actin filament based processGO:003297090.011
alternative mrna splicing via spliceosomeGO:000038010.011
negative regulation of dna metabolic processGO:005105340.011
positive regulation of myeloid cell differentiationGO:004563920.011
organ regenerationGO:003110010.011
regulation of protein targetingGO:190353320.011
negative regulation of cell communicationGO:0010648960.011
regulation of intracellular protein transportGO:003315730.011
hormone secretionGO:004687920.011
stem cell differentiationGO:00488631170.011
positive regulation of cellular component biogenesisGO:004408930.011
negative regulation of cell deathGO:0060548600.011
negative regulation of gene expressionGO:0010629650.011
positive regulation of epithelial cell differentiationGO:003085820.011
positive regulation of protein complex assemblyGO:003133420.011
regulation of mrna splicing via spliceosomeGO:004802430.011
organelle organizationGO:00069962270.011
convergent extension involved in gastrulationGO:0060027710.011
positive regulation of nucleotide catabolic processGO:003081310.011
striated muscle tissue developmentGO:00147061100.011
lipid storageGO:001991510.011
positive regulation of i kappab kinase nf kappab signalingGO:004312330.011
muscle cell migrationGO:001481240.011
regulation of systemic arterial blood pressureGO:000307310.011
positive regulation of purine nucleotide catabolic processGO:003312310.011
macromolecule biosynthetic processGO:00090592270.011
regulation of protein bindingGO:004339330.011
phosphorylationGO:0016310690.011
response to stressGO:00069502630.011
single organism organelle organizationGO:19025891990.011
regulation of protein polymerizationGO:003227120.011
positive regulation of leukocyte chemotaxisGO:000269010.011
nephron morphogenesisGO:007202820.011
regulation of cellular macromolecule biosynthetic processGO:20001122220.011
eye developmentGO:00016542770.011
gland developmentGO:00487321430.011
regulation of syncytium formation by plasma membrane fusionGO:006014220.011
ribosomal small subunit biogenesisGO:004227420.011
meiotic cell cycle processGO:190304630.011
erythrocyte differentiationGO:0030218540.011
homeostasis of number of cells within a tissueGO:004887340.011
otic vesicle developmentGO:0071599420.011
activation of mapk activityGO:000018730.010
organic cyclic compound metabolic processGO:19013603010.010
cellular component movementGO:00069283350.010
positive regulation of leukocyte differentiationGO:190210710.010
guanosine containing compound catabolic processGO:190106920.010
somatic cell dna recombinationGO:001644410.010
positive regulation of striated muscle cell differentiationGO:005115510.010
regulation of lipid transportGO:003236840.010
response to unfolded proteinGO:000698620.010
regulation of erk1 and erk2 cascadeGO:007037240.010
protein homooligomerizationGO:005126030.010
regulation of phosphorus metabolic processGO:0051174430.010
regulation of epithelial cell proliferationGO:005067830.010
multicellular organismal response to stressGO:003355520.010
sequestering of metal ionGO:005123830.010
regulation of cell projection assemblyGO:006049140.010
positive regulation of translationGO:004572710.010

cd74 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.040
immune system diseaseDOID:291400.020
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.015
muscular diseaseDOID:008000000.013
musculoskeletal system diseaseDOID:1700.013
nervous system diseaseDOID:86300.011
muscle tissue diseaseDOID:6600.010