Danio rerio

19 known processes

pi4kaa

phosphatidylinositol 4-kinase, catalytic, alpha a

(Aliases: pi4ka)

pi4kaa biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chordate embryonic developmentGO:00430092710.100
agingGO:000756820.090
larval developmentGO:000216420.089
cellular aromatic compound metabolic processGO:00067252950.083
cellular component morphogenesisGO:00329893360.083
modification dependent protein catabolic processGO:001994130.075
nitrogen compound metabolic processGO:00068073190.071
muscle structure developmentGO:00610611960.069
establishment of localizationGO:00512342440.066
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.066
cellular component assembly involved in morphogenesisGO:00109271070.065
ribonucleoside monophosphate catabolic processGO:000915840.065
signal transductionGO:00071654550.064
embryonic organ developmentGO:00485683810.062
response to chemicalGO:00422213200.062
cellular nitrogen compound metabolic processGO:00346412900.062
sensory organ developmentGO:00074233930.061
purine ribonucleoside monophosphate catabolic processGO:000916940.061
regulation of biological qualityGO:00650082630.059
single organism transportGO:00447652060.059
central nervous system developmentGO:00074173870.059
cell projection morphogenesisGO:00488582440.059
nucleoside monophosphate catabolic processGO:000912540.059
heterocycle metabolic processGO:00464832900.058
immune system processGO:00023762410.058
cell part morphogenesisGO:00329902460.057
head developmentGO:00603223030.056
purine nucleoside monophosphate catabolic processGO:000912840.056
organic cyclic compound metabolic processGO:19013603010.055
cellular biosynthetic processGO:00442492860.055
single organism localizationGO:19025782250.054
cilium morphogenesisGO:0060271850.054
heart developmentGO:00075073130.053
cellular protein catabolic processGO:004425740.052
cell morphogenesisGO:00009022890.052
regulation of signalingGO:00230512350.051
cellular macromolecule metabolic processGO:00442603910.050
maintenance of locationGO:005123540.049
embryo development ending in birth or egg hatchingGO:00097922710.048
multicellular organism growthGO:003526440.048
cell projection organizationGO:00300302840.048
blood vessel developmentGO:00015682460.047
neuron differentiationGO:00301823530.047
regulation of response to stimulusGO:00485832690.047
generation of neuronsGO:00486993850.046
heterocycle biosynthetic processGO:00181302150.045
proteolysis involved in cellular protein catabolic processGO:005160330.045
macromolecule biosynthetic processGO:00090592270.045
regulation of macromolecule metabolic processGO:00602553170.045
specification of symmetryGO:00097992040.045
positive regulation of cellular component biogenesisGO:004408930.045
mitochondrion organizationGO:000700540.044
organelle fusionGO:004828430.044
single organism metabolic processGO:00447102170.044
vasculature developmentGO:00019442780.044
morphogenesis of an epitheliumGO:00020093330.044
regulation of protein catabolic processGO:004217610.043
regulation of multicellular organism growthGO:004001440.043
organelle organizationGO:00069962270.043
regulation of gene expressionGO:00104682650.043
sensory organ morphogenesisGO:00905962000.042
guanosine containing compound metabolic processGO:190106840.042
modification dependent macromolecule catabolic processGO:004363230.042
determination of left right symmetryGO:00073681790.042
regulation of nucleobase containing compound metabolic processGO:00192192500.042
regulation of cell communicationGO:00106462320.041
regulation of nitrogen compound metabolic processGO:00511712510.041
cell surface receptor signaling pathwayGO:00071663250.041
nucleobase containing compound metabolic processGO:00061392740.040
determination of bilateral symmetryGO:00098552040.040
autophagyGO:000691440.040
ubiquitin dependent protein catabolic processGO:000651130.040
embryonic organ morphogenesisGO:00485622740.039
homeostatic processGO:00425921420.039
compound eye developmentGO:004874920.038
cytokinesisGO:000091030.038
response to external stimulusGO:00096052640.038
response to stressGO:00069502630.038
single organism organelle organizationGO:19025891990.038
regionalizationGO:00030022740.038
protein metabolic processGO:00195381830.038
proteasomal protein catabolic processGO:001049820.037
peptidyl serine phosphorylationGO:001810510.037
regulation of signal transductionGO:00099662250.036
positive regulation of protein complex assemblyGO:003133420.036
neuron developmentGO:00486662620.036
eye developmentGO:00016542770.036
cellular response to chemical stimulusGO:00708871570.035
cellular component movementGO:00069283350.035
regulation of synapse assemblyGO:005196330.035
brain developmentGO:00074202930.035
positive regulation of cellular catabolic processGO:003133130.035
organic substance biosynthetic processGO:19015762890.035
cell morphogenesis involved in differentiationGO:00009041950.034
negative regulation of cellular processGO:00485232830.034
transcription dna templatedGO:00063511810.034
cellular response to external stimulusGO:007149620.034
positive regulation of biological processGO:00485182530.034
response to organic substanceGO:00100331530.033
synaptic growth at neuromuscular junctionGO:005112420.033
phosphorus metabolic processGO:00067931090.033
locomotionGO:00400113130.033
regulation of cellular macromolecule biosynthetic processGO:20001122220.033
negative regulation of synapse assemblyGO:005196420.033
cilium organizationGO:0044782710.032
muscle organ developmentGO:00075171010.032
single organism membrane fusionGO:004480120.032
anterior posterior pattern specificationGO:00099521520.032
stem cell proliferationGO:007208940.032
hemopoiesisGO:00300971830.032
nucleic acid metabolic processGO:00903042440.031
gene expressionGO:00104672520.031
neuron projection developmentGO:00311751800.031
embryonic skeletal system morphogenesisGO:0048704930.030
transportGO:00068102200.030
cell migrationGO:00164772370.030
somitogenesisGO:0001756870.030
amine metabolic processGO:000930820.030
protein importGO:001703830.030
organic acid metabolic processGO:0006082310.029
hepaticobiliary system developmentGO:0061008980.029
membrane fusionGO:006102520.029
regulation of cytokine productionGO:000181730.029
regulation of metabolic processGO:00192223590.029
embryonic skeletal system developmentGO:0048706970.029
gland developmentGO:00487321430.029
positive regulation of catabolic processGO:000989640.029
guanosine containing compound catabolic processGO:190106920.029
small molecule metabolic processGO:0044281770.029
peptidyl serine modificationGO:001820920.029
localization of cellGO:00516742440.029
connective tissue developmentGO:0061448990.029
response to alkaloidGO:004327920.029
biosynthetic processGO:00090582940.029
positive regulation of transportGO:005105020.028
angiogenesisGO:00015251580.028
adult behaviorGO:003053420.028
tube morphogenesisGO:00352393490.028
ear developmentGO:00435831270.028
regulation of biosynthetic processGO:00098892500.028
axon developmentGO:00615641660.028
nuclear importGO:005117030.028
gtp metabolic processGO:004603940.028
cognitionGO:005089010.028
muscle cell differentiationGO:00426921390.028
digestive tract developmentGO:00485652650.028
cell morphogenesis involved in neuron differentiationGO:00486671630.028
negative regulation of biological processGO:00485193040.028
appendage developmentGO:0048736800.027
inner ear developmentGO:00488391260.027
cellular component assemblyGO:00226071700.027
nucleocytoplasmic transportGO:000691340.027
dorsal ventral pattern formationGO:00099531250.027
response to carbohydrateGO:000974330.027
embryonic cranial skeleton morphogenesisGO:0048701900.027
cellular macromolecule biosynthetic processGO:00346452240.027
nucleobase containing compound biosynthetic processGO:00346542050.027
regulation of cytoplasmic transportGO:190364940.027
positive regulation of purine nucleotide catabolic processGO:003312310.027
aromatic compound biosynthetic processGO:00194382170.026
cellular response to extracellular stimulusGO:003166820.026
regulation of protein modification by small protein conjugation or removalGO:190332030.026
regulation of autophagyGO:001050630.026
cellular amine metabolic processGO:004410620.026
regulation of cellular metabolic processGO:00313233200.026
regulation of developmental processGO:00507932470.026
somite developmentGO:0061053960.026
cell deathGO:00082191210.026
golgi vesicle transportGO:004819330.026
hindbrain developmentGO:0030902910.026
striated muscle tissue developmentGO:00147061100.026
skeletal muscle tissue developmentGO:0007519670.026
blood vessel morphogenesisGO:00485142160.025
developmental growthGO:00485891660.025
macromolecule modificationGO:00434121110.025
programmed cell deathGO:00125011190.025
liver developmentGO:0001889960.025
apoptotic processGO:00069151160.025
cellular component biogenesisGO:00440851780.025
protein localization to plasma membraneGO:007265910.025
phosphate containing compound metabolic processGO:00067961080.025
regulation of cellular biosynthetic processGO:00313262450.025
stem cell maintenanceGO:001982740.025
cellular component disassemblyGO:002241110.025
regulation of establishment of protein localizationGO:007020140.024
negative regulation of protein phosphorylationGO:000193340.024
regulation of nucleic acid templated transcriptionGO:19035062130.024
regulation of protein complex assemblyGO:004325430.024
regulation of rna metabolic processGO:00512522240.024
regulation of macromolecule biosynthetic processGO:00105562250.024
endosomal transportGO:001619720.024
skeletal system developmentGO:00015011810.024
response to uvGO:000941130.024
organonitrogen compound metabolic processGO:1901564740.024
oxoacid metabolic processGO:0043436310.024
striated muscle cell developmentGO:00550021080.024
cellular response to organic substanceGO:00713101050.024
ion transportGO:00068111140.024
skeletal muscle organ developmentGO:0060538780.023
cilium assemblyGO:0042384580.023
muscle tissue developmentGO:00605371100.023
neuroblast proliferationGO:000740520.023
protein modification processGO:00362111000.023
establishment of protein localization to organelleGO:007259440.023
hematopoietic or lymphoid organ developmentGO:00485341910.023
protein localization to nucleusGO:003450430.023
immune system developmentGO:00025201910.023
regulation of protein ubiquitinationGO:003139630.023
cellular nitrogen compound biosynthetic processGO:00442712180.023
regulation of primary metabolic processGO:00800903110.023
regulation of bindingGO:005109830.022
notochord developmentGO:0030903540.022
regulation of metal ion transportGO:001095940.022
gtp catabolic processGO:000618420.022
calcium ion transport into cytosolGO:006040230.022
cell substrate adhesionGO:003158940.022
rna metabolic processGO:00160702190.022
axonogenesisGO:00074091520.022
ear morphogenesisGO:0042471640.022
cytoskeleton organizationGO:0007010960.022
positive regulation of cytoskeleton organizationGO:005149530.022
cell motilityGO:00488702440.022
eye morphogenesisGO:00485921440.022
sequestering of calcium ionGO:005120830.022
protein targeting to nucleusGO:004474430.022
regulation of nucleoside metabolic processGO:000911820.021
regulation of synapse organizationGO:005080730.021
antimicrobial humoral responseGO:001973020.021
positive regulation of canonical wnt signaling pathwayGO:009026340.021
regulation of programmed cell deathGO:00430671010.021
response to drugGO:004249330.021
cellular protein modification processGO:00064641000.021
regulation of dendrite morphogenesisGO:004881430.021
regulation of dendrite developmentGO:005077330.021
myeloid cell differentiationGO:0030099860.021
cell matrix adhesionGO:000716040.021
regulation of protein transportGO:005122330.021
positive regulation of cytosolic calcium ion concentrationGO:000720440.020
forebrain developmentGO:0030900960.020
meiotic nuclear divisionGO:000712640.020
muscle cell developmentGO:00550011150.020
regulation of epithelial cell proliferationGO:005067830.020
rna biosynthetic processGO:00327741810.020
organic cyclic compound biosynthetic processGO:19013622230.020
regulation of circadian rhythmGO:004275240.020
protein import into nucleusGO:000660630.020
otic vesicle developmentGO:0071599420.020
establishment of localization in cellGO:0051649770.020
positive regulation of apoptotic signaling pathwayGO:200123510.020
intracellular signal transductionGO:0035556850.020
deathGO:00162651210.020
phagocytosisGO:000690930.020
regulation of cell deathGO:00109411030.020
nucleic acid templated transcriptionGO:00976591810.020
cellular protein metabolic processGO:00442671290.020
positive regulation of nucleoside metabolic processGO:004597910.020
segmentationGO:0035282970.020
cellular localizationGO:0051641970.020
negative regulation of sequestering of calcium ionGO:005128340.020
heart morphogenesisGO:00030071560.020
adherens junction organizationGO:003433240.020
cellular response to endogenous stimulusGO:0071495680.020
regulation of cellular ketone metabolic processGO:001056570.019
nuclear transportGO:005116940.019
regulation of cell substrate adhesionGO:001081010.019
stem cell differentiationGO:00488631170.019
atp catabolic processGO:000620040.019
skeletal system morphogenesisGO:00487051020.019
regulation of synaptic growth at neuromuscular junctionGO:000858210.019
kidney developmentGO:0001822920.019
membrane invaginationGO:001032410.019
negative regulation of mitosisGO:004583930.019
cellular ketone metabolic processGO:0042180110.019
camera type eye developmentGO:00430102220.019
regulation of cell activationGO:005086510.019
regulation of purine nucleotide catabolic processGO:003312120.019
regulation of cellular amine metabolic processGO:003323800.019
otic vesicle morphogenesisGO:0071600340.019
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.019
negative regulation of protein kinase activityGO:000646940.019
determination of heart left right asymmetryGO:00613711170.018
neurotransmitter transportGO:000683620.018
carbohydrate homeostasisGO:003350010.018
regulation of transcription dna templatedGO:00063552130.018
single organism nuclear importGO:190259330.018
regulation of protein localization to nucleusGO:190018020.018
cartilage developmentGO:0051216960.018
epithelial tube morphogenesisGO:00605621480.018
digestive system developmentGO:00551232890.018
regulation of rna biosynthetic processGO:20011412130.018
growthGO:00400071740.018
sensory system developmentGO:0048880760.018
wound healingGO:0042060900.018
carboxylic acid metabolic processGO:0019752220.018
regulation of intracellular protein transportGO:003315730.018
cellular response to starvationGO:000926710.018
mitochondrial transportGO:000683920.018
transmembrane transportGO:00550851200.018
protein dephosphorylationGO:000647030.018
regulation of endocrine processGO:004406020.018
exocytosisGO:000688710.017
tissue remodelingGO:004877140.017
regulation of reproductive processGO:200024140.017
cytosolic calcium ion transportGO:006040130.017
regulation of nucleotide catabolic processGO:003081120.017
positive regulation of nucleotide catabolic processGO:003081310.017
response to corticosteroidGO:003196010.017
cellular amino acid metabolic processGO:000652070.017
regulation of sequestering of calcium ionGO:005128240.017
metencephalon developmentGO:0022037270.017
protein homooligomerizationGO:005126030.017
embryonic heart tube morphogenesisGO:00031431080.017
regulation of nucleocytoplasmic transportGO:004682220.017
developmental growth involved in morphogenesisGO:0060560860.017
regulation of protein bindingGO:004339330.017
macromolecular complex disassemblyGO:003298410.017
regulation of apoptotic processGO:0042981980.017
regulation of synaptic plasticityGO:004816710.017
i kappab kinase nf kappab signalingGO:000724940.017
central nervous system neuron differentiationGO:0021953740.017
cellular response to nutrient levelsGO:003166920.017
regulation of gtp catabolic processGO:003312420.017
cortical actin cytoskeleton organizationGO:003086610.017
neuron neuron synaptic transmissionGO:000727010.017
cell fate commitmentGO:0045165990.017
regulation of extrinsic apoptotic signaling pathwayGO:200123630.017
negative regulation of kinase activityGO:003367340.017
post embryonic organ developmentGO:004856940.017
regulation of anatomical structure morphogenesisGO:00226031300.017
cell projection assemblyGO:0030031640.017
regulation of mrna processingGO:005068430.017
metal ion transportGO:0030001580.017
positive regulation of cytokine productionGO:000181920.017
mesenchyme developmentGO:00604851270.016
negative regulation of signalingGO:0023057960.016
digestive tract morphogenesisGO:00485462310.016
organelle localizationGO:0051640490.016
regulation of multicellular organismal developmentGO:20000262230.016
central nervous system neuron developmentGO:0021954290.016
positive regulation of jnk cascadeGO:004633030.016
embryonic limb morphogenesisGO:003032620.016
response to glucocorticoidGO:005138410.016
positive regulation of map kinase activityGO:004340630.016
neuron projection extensionGO:1990138450.016
response to endogenous stimulusGO:0009719830.016
positive regulation of cellular processGO:00485222010.016
axon extensionGO:0048675450.016
system processGO:00030081850.016
positive regulation of stress activated mapk cascadeGO:003287430.016
regulation of gtpase activityGO:004308720.016
negative regulation of response to stimulusGO:00485851040.016
regulation of cell shapeGO:000836010.016
hormone secretionGO:004687920.016
regulation of ion transmembrane transporter activityGO:003241220.016
sequestering of metal ionGO:005123830.016
meiotic cell cycle processGO:190304630.016
appendage morphogenesisGO:0035107560.016
regulation of cellular amino acid metabolic processGO:000652100.016
regulation of cell differentiationGO:00455951420.016
stem cell divisionGO:001714510.016
kupffer s vesicle developmentGO:0070121500.015
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.015
cellular response to oxygen levelsGO:007145310.015
cytokinetic processGO:003250620.015
organelle assemblyGO:00709251100.015
positive regulation of secretionGO:005104710.015
ion transmembrane transportGO:0034220910.015
positive regulation of i kappab kinase nf kappab signalingGO:004312330.015
regulation of protein import into nucleusGO:004230620.015
protein complex disassemblyGO:004324110.015
negative regulation of catabolic processGO:000989530.015
hormone transportGO:000991420.015
er to golgi vesicle mediated transportGO:000688810.015
inner ear morphogenesisGO:0042472630.015
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.015
rna modificationGO:000945120.015
internal protein amino acid acetylationGO:000647520.015
regulation of transmembrane transporter activityGO:002289820.015
regulation of multicellular organismal processGO:00512392770.015
regulation of blood pressureGO:000821710.015
regulation of protein targetingGO:190353320.015
behaviorGO:0007610740.015
negative regulation of nuclear divisionGO:005178430.015
lateral line system developmentGO:0048925760.015
lipid storageGO:001991510.015
positive regulation of gtpase activityGO:004354710.015
embryonic heart tube developmentGO:00350501330.014
neuron projection morphogenesisGO:00488121610.014
extrinsic apoptotic signaling pathwayGO:009719130.014
heart loopingGO:0001947940.014
protein polymerizationGO:005125840.014
microtubule based movementGO:0007018330.014
response to radiationGO:0009314510.014
erythrocyte homeostasisGO:0034101550.014
neurotransmitter secretionGO:000726920.014
cellular amide metabolic processGO:004360340.014
negative regulation of cell communicationGO:0010648960.014
positive regulation of signalingGO:0023056560.014
chemosensory behaviorGO:000763510.014
positive regulation of epithelial cell differentiationGO:003085820.014
cellular pigmentationGO:0033059300.014
developmental programmed cell deathGO:001062340.014
pancreas developmentGO:0031016840.014
b cell activationGO:004211320.014
positive regulation of cell cycleGO:004578730.014
response to oxygen radicalGO:000030520.014
positive regulation of cellular amino acid metabolic processGO:004576400.014
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.014
centrosome organizationGO:005129710.014
response to monosaccharideGO:003428430.014
positive regulation of immune effector processGO:000269930.014
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.014
fin morphogenesisGO:0033334530.014
peptide transportGO:001583310.013
neuromast developmentGO:0048884460.013
positive regulation of cell activationGO:005086710.013
cation transportGO:0006812810.013
regulation of neural precursor cell proliferationGO:200017730.013
erythrocyte differentiationGO:0030218540.013
negative regulation of signal transductionGO:0009968940.013
negative regulation of cytokine productionGO:000181810.013
lateral line developmentGO:0048882660.013
regulation of transporter activityGO:003240920.013
striated muscle cell differentiationGO:00511461290.013
negative regulation of multicellular organismal processGO:0051241690.013
startle responseGO:000196440.013
regulation of i kappab kinase nf kappab signalingGO:004312240.013
regulation of cell developmentGO:00602841000.013
melanin metabolic processGO:000658220.013
developmental cell growthGO:0048588520.013
synaptic transmission cholinergicGO:000727140.013
cortical cytoskeleton organizationGO:003086510.013
phagocytosis engulfmentGO:000691110.013
homeostasis of number of cellsGO:0048872620.013
female gonad developmentGO:000858540.013
interspecies interaction between organismsGO:004441940.013
protein acylationGO:004354330.013
otolith developmentGO:0048840320.013
oocyte anterior posterior axis specificationGO:000731440.013
mediolateral intercalationGO:006003130.013
regulation of stem cell proliferationGO:007209120.013
regulation of microtubule cytoskeleton organizationGO:007050730.013
response to oxygen containing compoundGO:1901700550.013
enzyme linked receptor protein signaling pathwayGO:00071671060.013
macroautophagyGO:001623610.013
cation transmembrane transportGO:0098655650.013
regulation of muscle contractionGO:000693730.013
xenobiotic metabolic processGO:000680540.012
symbiosis encompassing mutualism through parasitismGO:004440340.012
secondary metabolic processGO:001974830.012
negative regulation of apoptotic processGO:0043066550.012
cell cycle arrestGO:000705010.012
regulation of hormone secretionGO:004688320.012
response to external biotic stimulusGO:0043207970.012
regulation of neuronal synaptic plasticityGO:004816810.012
regulation of response to biotic stimulusGO:000283120.012
pectoral fin developmentGO:0033339500.012
response to transition metal nanoparticleGO:1990267280.012
cell growthGO:0016049570.012
rna localizationGO:000640340.012
carbon dioxide transportGO:001567030.012
viral processGO:001603210.012
somatic stem cell maintenanceGO:003501910.012
development of primary female sexual characteristicsGO:004654540.012
histone h3 k4 methylationGO:005156820.012
pectoral fin morphogenesisGO:0035138290.012
regulation of cell matrix adhesionGO:000195210.012
fin developmentGO:0033333770.012
release of sequestered calcium ion into cytosolGO:005120930.012
negative regulation of programmed cell deathGO:0043069580.012
cell cycle g2 m phase transitionGO:004483940.012
positive regulation of stem cell proliferationGO:200064810.012
regulation of transcription from rna polymerase ii promoterGO:00063571140.012
response to superoxideGO:000030320.012
positive regulation of response to stimulusGO:0048584800.012
renal system developmentGO:0072001940.012
positive regulation of inflammatory responseGO:005072910.012
superoxide metabolic processGO:000680120.012
pigmentationGO:0043473850.012
peptide metabolic processGO:000651810.012
regulation of protein polymerizationGO:003227120.012
camera type eye morphogenesisGO:00485931080.012
ovulation cycleGO:004269820.012
epidermal cell fate specificationGO:000995740.012
myeloid cell homeostasisGO:0002262560.011
positive regulation of secretion by cellGO:190353210.011
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.011
negative regulation of cytoplasmic transportGO:190365020.011
lymphocyte proliferationGO:004665110.011
microtubule based processGO:0007017600.011

pi4kaa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.061
nervous system diseaseDOID:86300.031
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
organ system cancerDOID:005068600.014
immune system diseaseDOID:291400.013
sensory system diseaseDOID:005015500.012
eye and adnexa diseaseDOID:149200.011