Danio rerio

81 known processes

nomo

nodal modulator

nomo biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.195
cell surface receptor signaling pathwayGO:00071663250.091
regulation of stem cell differentiationGO:200073640.079
sensory organ developmentGO:00074233930.067
regulation of gene expressionGO:00104682650.066
maintenance of locationGO:005123540.064
negative regulation of cellular processGO:00485232830.061
regulation of multicellular organismal processGO:00512392770.061
deathGO:00162651210.056
compound eye developmentGO:004874920.056
locomotionGO:00400113130.055
regulation of biological qualityGO:00650082630.053
determination of left right symmetryGO:00073681790.053
regulation of signal transductionGO:00099662250.052
biosynthetic processGO:00090582940.051
regulation of developmental processGO:00507932470.051
regulation of multicellular organismal developmentGO:20000262230.049
mitochondrion organizationGO:000700540.049
morphogenesis of an epitheliumGO:00020093330.049
regulation of response to stimulusGO:00485832690.048
positive regulation of biological processGO:00485182530.047
positive regulation of transportGO:005105020.047
regulation of nitrogen compound metabolic processGO:00511712510.047
cellular amino acid metabolic processGO:000652070.047
single organism transportGO:00447652060.046
embryonic organ developmentGO:00485683810.045
vasculature developmentGO:00019442780.045
specification of symmetryGO:00097992040.044
apoptotic process involved in developmentGO:190274220.044
determination of bilateral symmetryGO:00098552040.043
regulation of metabolic processGO:00192223590.042
establishment of localizationGO:00512342440.042
heterocycle metabolic processGO:00464832900.041
cell motilityGO:00488702440.041
brain developmentGO:00074202930.041
blood vessel developmentGO:00015682460.041
nucleic acid metabolic processGO:00903042440.041
programmed cell deathGO:00125011190.040
cellular biosynthetic processGO:00442492860.040
cell deathGO:00082191210.040
blood vessel morphogenesisGO:00485142160.039
cellular macromolecule metabolic processGO:00442603910.039
regionalizationGO:00030022740.038
regulation of macromolecule biosynthetic processGO:00105562250.038
nitrogen compound metabolic processGO:00068073190.037
regulation of cell projection assemblyGO:006049140.037
immune system processGO:00023762410.037
protein metabolic processGO:00195381830.037
regulation of multicellular organism growthGO:004001440.037
organic acid metabolic processGO:0006082310.036
tube morphogenesisGO:00352393490.036
rna metabolic processGO:00160702190.034
transportGO:00068102200.033
regulation of signalingGO:00230512350.033
lipid storageGO:001991510.033
protein secretionGO:000930610.032
oxoacid metabolic processGO:0043436310.032
regulation of cellular metabolic processGO:00313233200.032
regulation of primary metabolic processGO:00800903110.031
response to stressGO:00069502630.031
agingGO:000756820.031
regulation of cellular macromolecule biosynthetic processGO:20001122220.031
heterocycle biosynthetic processGO:00181302150.031
negative regulation of biological processGO:00485193040.031
ribonucleoside monophosphate catabolic processGO:000915840.030
epithelial tube morphogenesisGO:00605621480.030
lateral inhibitionGO:004633110.030
positive regulation of secretion by cellGO:190353210.030
regulation of macromolecule metabolic processGO:00602553170.030
protein localization to plasma membraneGO:007265910.030
signal transductionGO:00071654550.029
gtp catabolic processGO:000618420.029
hematopoietic or lymphoid organ developmentGO:00485341910.029
anterior posterior pattern specificationGO:00099521520.029
developmental programmed cell deathGO:001062340.029
macromolecule biosynthetic processGO:00090592270.029
carboxylic acid metabolic processGO:0019752220.029
mesenchyme developmentGO:00604851270.028
angiogenesisGO:00015251580.028
central nervous system developmentGO:00074173870.028
mesoderm developmentGO:0007498880.028
stem cell proliferationGO:007208940.028
organic substance biosynthetic processGO:19015762890.027
single organism metabolic processGO:00447102170.027
regulation of rna metabolic processGO:00512522240.027
positive regulation of secretionGO:005104710.027
phagocytosisGO:000690930.027
regulation of bindingGO:005109830.027
extrinsic apoptotic signaling pathwayGO:009719130.027
cellular component movementGO:00069283350.027
developmental growthGO:00485891660.026
regulation of cell communicationGO:00106462320.026
establishment of protein localization to organelleGO:007259440.026
fertilizationGO:000956630.026
cellular nitrogen compound biosynthetic processGO:00442712180.026
cellular amine metabolic processGO:004410620.025
embryo development ending in birth or egg hatchingGO:00097922710.025
post golgi vesicle mediated transportGO:000689210.025
establishment of localization in cellGO:0051649770.025
pole plasm assemblyGO:000731540.025
cellular nitrogen compound metabolic processGO:00346412900.024
positive regulation of exocytosisGO:004592110.024
localization of cellGO:00516742440.024
cellular response to starvationGO:000926710.024
apoptotic processGO:00069151160.024
regulation of establishment of protein localizationGO:007020140.023
neuron differentiationGO:00301823530.023
stem cell differentiationGO:00488631170.023
cellular response to external stimulusGO:007149620.023
cellular component morphogenesisGO:00329893360.023
regulation of cell shapeGO:000836010.023
response to chemicalGO:00422213200.023
organic cyclic compound metabolic processGO:19013603010.022
cellular aromatic compound metabolic processGO:00067252950.022
immune system developmentGO:00025201910.022
sensory perception of chemical stimulusGO:000760630.022
cell part morphogenesisGO:00329902460.022
positive regulation of cytosolic calcium ion concentrationGO:000720440.022
eye developmentGO:00016542770.022
heart developmentGO:00075073130.022
response to topologically incorrect proteinGO:003596620.021
chordate embryonic developmentGO:00430092710.021
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.021
negative regulation of activin receptor signaling pathwayGO:003292650.021
small molecule metabolic processGO:0044281770.021
regulation of biosynthetic processGO:00098892500.020
guanosine containing compound catabolic processGO:190106920.020
regulation of protein bindingGO:004339330.020
spermatid differentiationGO:004851520.020
dorsal ventral pattern formationGO:00099531250.020
regulation of cytoplasmic transportGO:190364940.020
regulation of protein transportGO:005122330.020
alcohol biosynthetic processGO:004616520.020
nucleoside monophosphate catabolic processGO:000912540.020
digestive tract developmentGO:00485652650.020
cell morphogenesisGO:00009022890.020
synaptic growth at neuromuscular junctionGO:005112420.020
stem cell divisionGO:001714510.020
cellular response to nutrient levelsGO:003166920.019
regulation of reproductive processGO:200024140.019
actin polymerization or depolymerizationGO:000815420.019
single organism localizationGO:19025782250.019
positive regulation of cell cycleGO:004578730.019
negative regulation of cell communicationGO:0010648960.019
endosomal transportGO:001619720.019
synaptic vesicle transportGO:004848910.019
lamellipodium organizationGO:009758110.019
cellular macromolecule biosynthetic processGO:00346452240.019
purine ribonucleoside monophosphate catabolic processGO:000916940.019
multi organism processGO:00517041340.019
positive regulation of cellular component biogenesisGO:004408930.019
digestive system developmentGO:00551232890.019
embryonic heart tube developmentGO:00350501330.019
neurotransmitter transportGO:000683620.019
cellular protein catabolic processGO:004425740.018
renal system developmentGO:0072001940.018
adult behaviorGO:003053420.018
cell migration involved in gastrulationGO:0042074790.018
protein modification processGO:00362111000.018
regulation of protein complex assemblyGO:004325430.018
cartilage developmentGO:0051216960.018
regulation of cellular amino acid metabolic processGO:000652100.018
positive regulation of apoptotic signaling pathwayGO:200123510.018
head developmentGO:00603223030.018
cytoplasm organizationGO:000702840.018
ear developmentGO:00435831270.017
nucleic acid templated transcriptionGO:00976591810.017
atp catabolic processGO:000620040.017
gastrulationGO:00073692080.017
regulation of cytokine productionGO:000181730.017
regulation of extrinsic apoptotic signaling pathwayGO:200123630.017
system processGO:00030081850.017
exocytosisGO:000688710.017
regulation of cellular amine metabolic processGO:003323800.017
regulation of nucleobase containing compound metabolic processGO:00192192500.017
positive regulation of response to stimulusGO:0048584800.017
cellular protein metabolic processGO:00442671290.017
somitogenesisGO:0001756870.017
positive regulation of canonical wnt signaling pathwayGO:009026340.017
response to unfolded proteinGO:000698620.017
regulation of metal ion transportGO:001095940.017
amine metabolic processGO:000930820.017
multicellular organism growthGO:003526440.017
negative regulation of signal transductionGO:0009968940.017
rna biosynthetic processGO:00327741810.017
regulation of cellular biosynthetic processGO:00313262450.017
actin filament based movementGO:003004810.017
connective tissue developmentGO:0061448990.017
maternal determination of anterior posterior axis embryoGO:000835840.017
inner ear developmentGO:00488391260.017
female gonad developmentGO:000858540.017
negative regulation of multicellular organismal processGO:0051241690.017
guanosine containing compound metabolic processGO:190106840.017
regulation of hematopoietic progenitor cell differentiationGO:190153210.016
microtubule cytoskeleton organization involved in mitosisGO:190285010.016
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.016
apoptotic process involved in morphogenesisGO:006056120.016
digestive tract morphogenesisGO:00485462310.016
zymogen activationGO:003163830.016
nucleobase containing compound biosynthetic processGO:00346542050.016
response to drugGO:004249330.016
determination of left right asymmetry in lateral mesodermGO:0003140200.016
negative regulation of kinase activityGO:003367340.016
regulation of protein catabolic processGO:004217610.016
ion transmembrane transportGO:0034220910.016
regulation of epithelial cell proliferationGO:005067830.016
single organism membrane fusionGO:004480120.016
regulation of neurotransmitter secretionGO:004692810.016
olfactory lobe developmentGO:002198840.016
aromatic compound biosynthetic processGO:00194382170.016
single fertilizationGO:000733830.016
cellular response to extracellular stimulusGO:003166820.016
regulation of i kappab kinase nf kappab signalingGO:004312240.016
membrane fusionGO:006102520.016
regulation of synapse assemblyGO:005196330.016
semicircular canal developmentGO:0060872240.016
meiotic chromosome segregationGO:004513230.015
astrocyte differentiationGO:004870810.015
skin developmentGO:0043588540.015
synaptic vesicle recyclingGO:003646510.015
stem cell maintenanceGO:001982740.015
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.015
regulation of cell activationGO:005086510.015
leukocyte proliferationGO:007066110.015
organonitrogen compound metabolic processGO:1901564740.015
cellular ketone metabolic processGO:0042180110.015
positive regulation of dna metabolic processGO:005105410.015
heart morphogenesisGO:00030071560.015
positive regulation of cell activationGO:005086710.014
regulation of muscle contractionGO:000693730.014
establishment of synaptic vesicle localizationGO:009748010.014
positive regulation of cell adhesionGO:004578510.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.014
determination of heart left right asymmetryGO:00613711170.014
negative regulation of stem cell differentiationGO:200073720.014
negative regulation of catabolic processGO:000989530.014
regulation of nucleotide catabolic processGO:003081120.014
cellular amide metabolic processGO:004360340.014
regulation of synapse organizationGO:005080730.014
enzyme linked receptor protein signaling pathwayGO:00071671060.014
positive regulation of map kinase activityGO:004340630.014
regulation of rna biosynthetic processGO:20011412130.014
modification dependent macromolecule catabolic processGO:004363230.014
meiotic cell cycle processGO:190304630.014
spindle assemblyGO:005122520.014
mitochondrial transportGO:000683920.014
protein stabilizationGO:005082120.014
spermatid developmentGO:000728620.014
tissue remodelingGO:004877140.014
female sex differentiationGO:004666040.014
regulation of response to extracellular stimulusGO:003210410.014
gene expressionGO:00104672520.014
cellular protein modification processGO:00064641000.014
somatic muscle developmentGO:000752540.014
regulation of nucleic acid templated transcriptionGO:19035062130.014
somite developmentGO:0061053960.014
regulation of filopodium assemblyGO:005148920.013
cellular response to topologically incorrect proteinGO:003596720.013
purine nucleoside monophosphate catabolic processGO:000912840.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
convergent extensionGO:00600261180.013
pigmentationGO:0043473850.013
negative regulation of epithelial cell proliferationGO:005068010.013
regulation of gtp catabolic processGO:003312420.013
nucleobase containing compound metabolic processGO:00061392740.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.013
negative regulation of reproductive processGO:200024230.013
cellular component biogenesisGO:00440851780.013
homeostatic processGO:00425921420.013
cytosolic calcium ion transportGO:006040130.013
wound healingGO:0042060900.013
fat soluble vitamin metabolic processGO:000677540.013
gtp metabolic processGO:004603940.013
protein acetylationGO:000647320.013
organic cyclic compound biosynthetic processGO:19013622230.013
cellular component disassemblyGO:002241110.013
peptidyl serine phosphorylationGO:001810510.013
cranial nerve developmentGO:0021545420.013
negative regulation of chemotaxisGO:005092240.013
forebrain developmentGO:0030900960.013
cellular component assemblyGO:00226071700.013
positive regulation of cellular amine metabolic processGO:003324000.013
actin filament polymerizationGO:003004120.013
i kappab kinase nf kappab signalingGO:000724940.013
negative regulation of nodal signaling pathwayGO:190010840.012
regulation of localizationGO:00328791040.012
regulation of myotube differentiationGO:001083020.012
regulation of wound healingGO:006104120.012
membrane lipid biosynthetic processGO:004646720.012
negative regulation of mapk cascadeGO:004340940.012
positive regulation of cellular catabolic processGO:003133130.012
hematopoietic stem cell differentiationGO:0060218200.012
cytokinesisGO:000091030.012
phagocytosis engulfmentGO:000691110.012
heart loopingGO:0001947940.012
neurotransmitter secretionGO:000726920.012
negative regulation of mesoderm developmentGO:200038150.012
cellular response to hypoxiaGO:007145610.012
hemopoiesisGO:00300971830.012
negative regulation of cytokine productionGO:000181810.012
wnt signaling pathwayGO:0016055800.012
nephron tubule morphogenesisGO:007207810.012
protein import into nucleusGO:000660630.012
negative regulation of response to stimulusGO:00485851040.012
sprouting angiogenesisGO:0002040530.012
signal transduction in absence of ligandGO:003803410.012
positive regulation of muscle cell differentiationGO:005114910.012
positive regulation of notch signaling pathwayGO:004574730.012
protein targeting to nucleusGO:004474430.012
protein acylationGO:004354330.012
ubiquitin dependent protein catabolic processGO:000651130.012
oocyte anterior posterior axis specificationGO:000731440.012
regulation of purine nucleotide catabolic processGO:003312120.012
proteolysis involved in cellular protein catabolic processGO:005160330.012
autophagyGO:000691440.012
production of molecular mediator of immune responseGO:000244020.012
embryonic heart tube morphogenesisGO:00031431080.012
macroautophagyGO:001623610.012
regulation of cellular component organizationGO:0051128860.012
response to external stimulusGO:00096052640.012
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.012
protein polymerizationGO:005125840.012
tissue regenerationGO:0042246740.012
kidney developmentGO:0001822920.012
dicarboxylic acid transportGO:000683510.012
epithelial cell morphogenesisGO:000338220.012
er to golgi vesicle mediated transportGO:000688810.012
generation of neuronsGO:00486993850.012
regulation of calcium ion transportGO:005192420.011
regulation of protein import into nucleusGO:004230620.011
skeletal system developmentGO:00015011810.011
negative regulation of autophagyGO:001050710.011
regulation of synaptic plasticityGO:004816710.011
negative regulation of protein phosphorylationGO:000193340.011
cellular monovalent inorganic cation homeostasisGO:003000420.011
endothelial cell fate commitmentGO:006083930.011
positive regulation of catabolic processGO:000989640.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
urogenital system developmentGO:0001655970.011
negative regulation of intracellular transportGO:003238730.011
peptidyl lysine acetylationGO:001839420.011
g2 m transition of mitotic cell cycleGO:000008640.011
regulation of neurotransmitter transportGO:005158810.011
regulation of blood vessel sizeGO:005088020.011
nuclear migrationGO:000709730.011
positive regulation of neuron deathGO:190121610.011
post embryonic organ developmentGO:004856940.011
cell cycle arrestGO:000705010.011
ion homeostasisGO:0050801410.011
organelle assemblyGO:00709251100.011
positive regulation of cytoskeleton organizationGO:005149530.011
segmentationGO:0035282970.011
centrosome organizationGO:005129710.011
organelle organizationGO:00069962270.011
hormone transportGO:000991420.011
regulation of protein ubiquitinationGO:003139630.011
regulation of tube sizeGO:003515020.011
intracellular signal transductionGO:0035556850.011
cell migrationGO:00164772370.011
protein complex localizationGO:003150310.011
membrane invaginationGO:001032410.011
centrosome cycleGO:000709810.011
pharyngeal muscle developmentGO:004328240.011
neuroblast proliferationGO:000740520.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.011
reactive oxygen species metabolic processGO:007259360.011
response to nutrientGO:000758430.011
organelle fusionGO:004828430.011
regulation of protein polymerizationGO:003227120.011
protein homooligomerizationGO:005126030.011
cellular response to oxygen levelsGO:007145310.011
ovulation cycleGO:004269820.011
peptide transportGO:001583310.011
multicellular organism reproductionGO:0032504350.011
forebrain cell migrationGO:002188510.011
regulation of cell deathGO:00109411030.011
transcription dna templatedGO:00063511810.011
epithelial cell differentiationGO:00308551160.011
taxisGO:00423301090.011
regulation of cell differentiationGO:00455951420.011
negative regulation of chromosome organizationGO:200125110.011
protein importGO:001703830.011
golgi vesicle transportGO:004819330.011
nephron morphogenesisGO:007202820.010
regenerationGO:0031099910.010
regulation of cellular ketone metabolic processGO:001056570.010
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.010
regulation of blood pressureGO:000821710.010
regulation of gtpase activityGO:004308720.010
lipid catabolic processGO:001604240.010
positive regulation of protein complex assemblyGO:003133420.010
branching morphogenesis of a nerveGO:004875540.010
peptidyl serine modificationGO:001820920.010
nerve developmentGO:0021675450.010
nuclear importGO:005117030.010
secondary metabolic processGO:001974830.010
carbohydrate homeostasisGO:003350010.010
internal protein amino acid acetylationGO:000647520.010
regulation of cell developmentGO:00602841000.010
gland developmentGO:00487321430.010
regulation of nucleoside metabolic processGO:000911820.010
olfactory bulb developmentGO:002177240.010
negative regulation of cytoplasmic transportGO:190365020.010
proteasomal protein catabolic processGO:001049820.010
ovulation cycle processGO:002260220.010
positive regulation of striated muscle cell differentiationGO:005115510.010
transmission of nerve impulseGO:0019226190.010
positive regulation of i kappab kinase nf kappab signalingGO:004312330.010
negative regulation of signalingGO:0023057960.010
nephron epithelium morphogenesisGO:007208810.010
protein complex disassemblyGO:004324110.010
regulation of response to nutrient levelsGO:003210710.010
regulation of protein localization to plasma membraneGO:190307610.010

nomo disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.025
disease of metabolismDOID:001466700.019
inherited metabolic disorderDOID:65500.019
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.015
organ system cancerDOID:005068600.015
musculoskeletal system diseaseDOID:1700.015
nervous system diseaseDOID:86300.015
cardiovascular system diseaseDOID:128700.013
bone diseaseDOID:008000100.011
connective tissue diseaseDOID:6500.011