Danio rerio

0 known processes

irx5b

iroquois homeobox protein 5b

(Aliases: iro5b,ziro5b)

irx5b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sensory organ developmentGO:00074233930.520
central nervous system developmentGO:00074173870.388
sensory organ morphogenesisGO:00905962000.256
head developmentGO:00603223030.225
nucleic acid templated transcriptionGO:00976591810.220
ear developmentGO:00435831270.211
transcription from rna polymerase ii promoterGO:0006366800.207
negative regulation of cellular processGO:00485232830.193
tube morphogenesisGO:00352393490.190
cell morphogenesisGO:00009022890.175
heterocycle biosynthetic processGO:00181302150.165
regionalizationGO:00030022740.162
cellular component movementGO:00069283350.150
transcription dna templatedGO:00063511810.149
larval developmentGO:000216420.146
macromolecule biosynthetic processGO:00090592270.146
mesoderm morphogenesisGO:0048332510.146
regulation of response to stimulusGO:00485832690.146
neuron differentiationGO:00301823530.144
negative regulation of biological processGO:00485193040.144
gene expressionGO:00104672520.138
cellular component morphogenesisGO:00329893360.135
regulation of nucleic acid templated transcriptionGO:19035062130.126
cellular biosynthetic processGO:00442492860.123
brain developmentGO:00074202930.122
regulation of macromolecule metabolic processGO:00602553170.119
regulation of gene expressionGO:00104682650.113
diencephalon developmentGO:0021536580.109
regulation of transcription from rna polymerase ii promoterGO:00063571140.107
dorsal ventral pattern formationGO:00099531250.104
regulation of rna biosynthetic processGO:20011412130.103
segmentationGO:0035282970.103
digestive system developmentGO:00551232890.100
regulation of developmental processGO:00507932470.098
regulation of multicellular organismal processGO:00512392770.097
digestive tract morphogenesisGO:00485462310.096
aromatic compound biosynthetic processGO:00194382170.093
morphogenesis of an epitheliumGO:00020093330.092
regulation of macromolecule biosynthetic processGO:00105562250.092
rna biosynthetic processGO:00327741810.091
response to external stimulusGO:00096052640.089
locomotionGO:00400113130.089
negative regulation of developmental processGO:0051093650.088
negative regulation of protein phosphorylationGO:000193340.087
cellular nitrogen compound biosynthetic processGO:00442712180.083
regulation of transcription dna templatedGO:00063552130.083
otolith developmentGO:0048840320.082
inner ear developmentGO:00488391260.081
embryonic organ developmentGO:00485683810.080
cognitionGO:005089010.078
cellular protein catabolic processGO:004425740.078
camera type eye developmentGO:00430102220.078
neuron projection developmentGO:00311751800.078
cellular nitrogen compound metabolic processGO:00346412900.077
regulation of primary metabolic processGO:00800903110.076
agingGO:000756820.075
response to chemicalGO:00422213200.075
gastrulationGO:00073692080.074
embryonic organ morphogenesisGO:00485622740.072
regulation of metabolic processGO:00192223590.072
cell morphogenesis involved in differentiationGO:00009041950.070
cellular macromolecule metabolic processGO:00442603910.069
nitrogen compound metabolic processGO:00068073190.069
cellular aromatic compound metabolic processGO:00067252950.066
enzyme linked receptor protein signaling pathwayGO:00071671060.063
protein metabolic processGO:00195381830.062
regulation of synapse assemblyGO:005196330.062
renal system developmentGO:0072001940.061
camera type eye morphogenesisGO:00485931080.061
compound eye developmentGO:004874920.060
negative regulation of multicellular organismal processGO:0051241690.059
inner ear morphogenesisGO:0042472630.059
regulation of cellular metabolic processGO:00313233200.057
cell projection morphogenesisGO:00488582440.056
cell part morphogenesisGO:00329902460.056
cellular macromolecule biosynthetic processGO:00346452240.055
biosynthetic processGO:00090582940.055
rna metabolic processGO:00160702190.055
regulation of biosynthetic processGO:00098892500.054
regulation of cellular biosynthetic processGO:00313262450.053
retina morphogenesis in camera type eyeGO:0060042790.053
programmed cell deathGO:00125011190.052
nucleobase containing compound biosynthetic processGO:00346542050.052
axon guidanceGO:0007411860.051
hindbrain developmentGO:0030902910.051
stem cell proliferationGO:007208940.051
regulation of multicellular organismal developmentGO:20000262230.050
regulation of nitrogen compound metabolic processGO:00511712510.050
actin filament based movementGO:003004810.049
eye developmentGO:00016542770.049
development of primary female sexual characteristicsGO:004654540.048
nucleic acid metabolic processGO:00903042440.048
ear morphogenesisGO:0042471640.047
regulation of biological qualityGO:00650082630.047
generation of neuronsGO:00486993850.045
regulation of signal transductionGO:00099662250.045
immune system processGO:00023762410.044
developmental growthGO:00485891660.044
cell deathGO:00082191210.043
hemopoiesisGO:00300971830.043
negative regulation of cell differentiationGO:0045596460.042
neuron developmentGO:00486662620.042
positive regulation of biological processGO:00485182530.042
localization of cellGO:00516742440.041
cell morphogenesis involved in neuron differentiationGO:00486671630.041
organic substance biosynthetic processGO:19015762890.041
neuron projection morphogenesisGO:00488121610.041
deathGO:00162651210.041
mesoderm developmentGO:0007498880.040
regulation of anatomical structure morphogenesisGO:00226031300.039
chemotaxisGO:00069351040.039
stem cell maintenanceGO:001982740.039
mechanoreceptor differentiationGO:0042490370.039
regulation of cell communicationGO:00106462320.039
cell projection organizationGO:00300302840.038
regulation of apoptotic processGO:0042981980.038
mesenchyme developmentGO:00604851270.038
negative regulation of protein kinase activityGO:000646940.038
hair cell differentiationGO:0035315320.038
regulation of cellular macromolecule biosynthetic processGO:20001122220.037
taxisGO:00423301090.037
kidney developmentGO:0001822920.037
organic cyclic compound metabolic processGO:19013603010.037
negative regulation of axon guidanceGO:190266810.037
negative regulation of chemotaxisGO:005092240.036
organic acid metabolic processGO:0006082310.036
digestive tract developmentGO:00485652650.036
female gonad developmentGO:000858540.036
sensory system developmentGO:0048880760.035
outflow tract morphogenesisGO:000315110.035
amine metabolic processGO:000930820.034
forebrain developmentGO:0030900960.034
regulation of cellular component organizationGO:0051128860.034
neuron projection guidanceGO:0097485860.034
striated muscle tissue developmentGO:00147061100.034
facial nerve developmentGO:002156130.034
regulation of nucleobase containing compound metabolic processGO:00192192500.034
appendage morphogenesisGO:0035107560.034
eye morphogenesisGO:00485921440.033
endocrine system developmentGO:0035270650.033
negative regulation of neurogenesisGO:0050768200.033
notochord developmentGO:0030903540.033
muscle cell developmentGO:00550011150.032
regulation of multicellular organism growthGO:004001440.032
negative regulation of macromolecule metabolic processGO:0010605760.032
otic vesicle developmentGO:0071599420.031
negative regulation of cell morphogenesis involved in differentiationGO:001077180.031
regulation of cell differentiationGO:00455951420.031
regulation of reproductive processGO:200024140.031
facial nerve morphogenesisGO:002161010.030
signal transductionGO:00071654550.030
sympathetic nervous system developmentGO:004848530.030
mitochondrion organizationGO:000700540.030
regulation of cytokine productionGO:000181730.029
response to stressGO:00069502630.029
epithelial cell differentiationGO:00308551160.029
negative regulation of cellular metabolic processGO:0031324770.029
regulation of rna metabolic processGO:00512522240.029
nucleobase containing compound metabolic processGO:00061392740.029
fin developmentGO:0033333770.029
heart developmentGO:00075073130.028
positive regulation of transportGO:005105020.028
mechanosensory lateral line system developmentGO:0048881490.028
regulation of blood pressureGO:000821710.028
muscle tissue developmentGO:00605371100.028
negative regulation of nitrogen compound metabolic processGO:0051172590.028
embryonic limb morphogenesisGO:003032620.027
blood vessel developmentGO:00015682460.027
secondary metabolic processGO:001974830.027
organic cyclic compound biosynthetic processGO:19013622230.027
negative regulation of cell developmentGO:0010721260.027
cellular ketone metabolic processGO:0042180110.026
smoothened signaling pathwayGO:0007224300.026
peripheral nervous system developmentGO:0007422550.026
regulation of embryonic developmentGO:0045995470.026
regulation of response to stressGO:0080134360.025
cellular amide metabolic processGO:004360340.025
rhombomere developmentGO:0021546190.025
axonogenesisGO:00074091520.025
cellular amine metabolic processGO:004410620.025
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.025
negative regulation of metabolic processGO:0009892860.025
negative regulation of cell deathGO:0060548600.025
regulation of neurogenesisGO:0050767870.025
negative regulation of cell communicationGO:0010648960.025
embryonic retina morphogenesis in camera type eyeGO:0060059220.024
somite developmentGO:0061053960.024
regulation of programmed cell deathGO:00430671010.024
negative regulation of nervous system developmentGO:0051961220.024
carboxylic acid metabolic processGO:0019752220.024
muscle organ developmentGO:00075171010.023
regulation of receptor activityGO:001046920.023
negative regulation of signalingGO:0023057960.023
astrocyte differentiationGO:004870810.023
anatomical structure arrangementGO:004853220.023
regulation of stem cell differentiationGO:200073640.023
notochord cell differentiationGO:0060034180.023
cell surface receptor signaling pathwayGO:00071663250.023
regulation of syncytium formation by plasma membrane fusionGO:006014220.023
negative regulation of kinase activityGO:003367340.023
locus ceruleus developmentGO:002170330.022
central nervous system myelinationGO:002201020.022
cell proliferationGO:0008283800.022
protein import into nucleusGO:000660630.022
protein importGO:001703830.022
oxoacid metabolic processGO:0043436310.022
autonomic nervous system developmentGO:0048483190.022
posterior lateral line neuromast hair cell differentiationGO:004892380.022
retina development in camera type eyeGO:00600411460.022
cellular component assemblyGO:00226071700.022
negative regulation of neuron differentiationGO:0045665100.022
negative regulation of signal transductionGO:0009968940.022
posterior lateral line neuromast developmentGO:0048919200.022
action potentialGO:0001508190.022
cellular response to chemical stimulusGO:00708871570.021
negative regulation of protein serine threonine kinase activityGO:007190120.021
gland developmentGO:00487321430.021
central nervous system neuron differentiationGO:0021953740.021
response to alkaloidGO:004327920.021
multi organism processGO:00517041340.021
retina layer formationGO:0010842240.021
regulation of protein transportGO:005122330.021
regulation of gastrulationGO:0010470240.021
cell migrationGO:00164772370.021
response to nutrientGO:000758430.021
multicellular organism growthGO:003526440.021
negative regulation of response to stimulusGO:00485851040.020
regulation of peptidyl tyrosine phosphorylationGO:005073010.020
cell motilityGO:00488702440.020
appendage developmentGO:0048736800.020
axon ensheathment in central nervous systemGO:003229120.020
regulation of cellular ketone metabolic processGO:001056570.020
determination of bilateral symmetryGO:00098552040.020
positive regulation of transcription dna templatedGO:0045893570.020
macromolecule modificationGO:00434121110.020
protein localization to nucleusGO:003450430.019
hindbrain morphogenesisGO:0021575220.019
chordate embryonic developmentGO:00430092710.019
lateral line developmentGO:0048882660.019
phagocytosisGO:000690930.019
modification dependent protein catabolic processGO:001994130.019
regulation of cellular amine metabolic processGO:003323800.019
positive regulation of developmental processGO:0051094500.019
regulation of cell shapeGO:000836010.019
adult behaviorGO:003053420.019
maintenance of locationGO:005123540.019
negative regulation of programmed cell deathGO:0043069580.019
ubiquitin dependent protein catabolic processGO:000651130.019
positive regulation of rna biosynthetic processGO:1902680570.019
negative regulation of axon extension involved in axon guidanceGO:004884310.018
neuromast mantle cell differentiationGO:004888810.018
pronephros developmentGO:0048793690.018
regulation of growthGO:0040008420.018
axon developmentGO:00615641660.018
cellular component biogenesisGO:00440851780.018
skin developmentGO:0043588540.018
response to organic substanceGO:00100331530.018
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.018
oocyte maturationGO:000155640.018
erk1 and erk2 cascadeGO:007037140.018
negative regulation of rna biosynthetic processGO:1902679450.018
neuromast developmentGO:0048884460.018
positive regulation of cellular amino acid metabolic processGO:004576400.018
cell fate commitment involved in formation of primary germ layerGO:0060795260.018
developmental growth involved in morphogenesisGO:0060560860.017
somitogenesisGO:0001756870.017
nuclear transportGO:005116940.017
hormone transportGO:000991420.017
nuclear importGO:005117030.017
regulation of mrna processingGO:005068430.017
proteolysis involved in cellular protein catabolic processGO:005160330.017
female sex differentiationGO:004666040.017
mesodermal cell fate specificationGO:0007501120.017
negative regulation of mapk cascadeGO:004340940.017
sensory neuron axon guidanceGO:009737430.017
anterior posterior pattern specificationGO:00099521520.017
embryo development ending in birth or egg hatchingGO:00097922710.017
neuron fate commitmentGO:0048663260.016
spinal cord association neuron differentiationGO:002152710.016
regulation of tube sizeGO:003515020.016
rhombomere morphogenesisGO:0021593170.016
fin morphogenesisGO:0033334530.016
collateral sproutingGO:004866890.016
single organism metabolic processGO:00447102170.016
regulation of developmental growthGO:0048638380.016
positive regulation of multicellular organismal processGO:0051240520.016
posterior lateral line neuromast mantle cell differentiationGO:004892410.016
epithelial cell morphogenesisGO:000338220.016
negative regulation of biosynthetic processGO:0009890550.016
blood vessel morphogenesisGO:00485142160.015
post embryonic organ developmentGO:004856940.015
mesoderm formationGO:0001707430.015
lateral line system developmentGO:0048925760.015
regulation of nervous system developmentGO:0051960900.015
regulation of protein localization to nucleusGO:190018020.015
regulation of cell developmentGO:00602841000.015
dorsal spinal cord developmentGO:002151610.015
pigmentationGO:0043473850.015
nucleocytoplasmic transportGO:000691340.015
adenohypophysis developmentGO:0021984150.015
regulation of establishment of protein localizationGO:007020140.015
epithelial tube morphogenesisGO:00605621480.015
cell fate commitmentGO:0045165990.015
positive regulation of gene expressionGO:0010628710.015
positive regulation of cell communicationGO:0010647560.015
endocrine pancreas developmentGO:0031018270.015
positive regulation of secretionGO:005104710.015
peptide metabolic processGO:000651810.015
embryonic pectoral fin morphogenesisGO:0035118240.015
epidermal cell differentiationGO:0009913360.015
apoptotic processGO:00069151160.015
regulation of systemic arterial blood pressureGO:000307310.015
negative regulation of gene expressionGO:0010629650.015
regulation of neuron differentiationGO:0045664560.015
regenerationGO:0031099910.015
regulation of ion transmembrane transporter activityGO:003241220.015
peptidyl serine phosphorylationGO:001810510.014
negative regulation of rna metabolic processGO:0051253480.014
lipid metabolic processGO:0006629520.014
establishment of protein localization to organelleGO:007259440.014
dendrite guidanceGO:007098300.014
cellular hormone metabolic processGO:0034754190.014
negative regulation of reproductive processGO:200024230.014
proteasomal protein catabolic processGO:001049820.014
limbic system developmentGO:0021761160.014
b cell activationGO:004211320.014
tissue regenerationGO:0042246740.014
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.014
tissue remodelingGO:004877140.014
positive regulation of cell adhesionGO:004578510.014
spinal cord developmentGO:0021510460.014
forebrain cell migrationGO:002188510.014
growthGO:00400071740.014
cellular response to extracellular stimulusGO:003166820.014
cell growthGO:0016049570.014
symbiosis encompassing mutualism through parasitismGO:004440340.014
regulation of cellular component sizeGO:0032535300.014
peripheral nervous system neuron differentiationGO:0048934280.014
positive regulation of nitrogen compound metabolic processGO:0051173690.014
epidermis developmentGO:0008544480.014
response to drugGO:004249330.014
regulation of cell deathGO:00109411030.014
mesenchymal cell differentiationGO:0048762870.014
single organism biosynthetic processGO:0044711710.014
response to xenobiotic stimulusGO:0009410450.014
regulation of cellular amino acid metabolic processGO:000652100.014
regulation of cell fate commitmentGO:0010453220.013
regulation of anatomical structure sizeGO:0090066330.013
negative regulation of transcription dna templatedGO:0045892450.013
cellular amino acid metabolic processGO:000652070.013
regulation of dendrite developmentGO:005077330.013
protein dephosphorylationGO:000647030.013
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.013
melanin metabolic processGO:000658220.013
regulation of cell fate specificationGO:0042659200.013
regulation of erk1 and erk2 cascadeGO:007037240.013
regulation of protein import into nucleusGO:004230620.013
organonitrogen compound metabolic processGO:1901564740.013
mesenchymal cell developmentGO:0014031780.013
nephron tubule morphogenesisGO:007207810.013
regulation of protein complex assemblyGO:004325430.013
heterocycle metabolic processGO:00464832900.013
embryonic heart tube morphogenesisGO:00031431080.013
skeletal muscle tissue developmentGO:0007519670.013
synaptic growth at neuromuscular junctionGO:005112420.013
regulation of protein targetingGO:190353320.013
cell agingGO:000756920.013
regulation of synapse organizationGO:005080730.013
vasculature developmentGO:00019442780.013
startle responseGO:000196440.013
regulation of protein modification by small protein conjugation or removalGO:190332030.013
proximal distal pattern formationGO:000995410.013
somatic muscle developmentGO:000752540.013
positive regulation of apoptotic processGO:0043065290.013
regulation of cellular carbohydrate metabolic processGO:001067540.013
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.013
response to vitamin b3GO:003355220.012
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.012
pectoral fin developmentGO:0033339500.012
immune system developmentGO:00025201910.012
ameboidal type cell migrationGO:00016671430.012
epithelial cell developmentGO:0002064420.012
modification dependent macromolecule catabolic processGO:004363230.012
cell cell signalingGO:0007267520.012
monovalent inorganic cation transportGO:0015672420.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
organonitrogen compound biosynthetic processGO:1901566470.012
muscle cell differentiationGO:00426921390.012
regulation of signalingGO:00230512350.012
regulation of bindingGO:005109830.012
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.012
positive regulation of cell cycleGO:004578730.012
lipid homeostasisGO:005508830.012
system processGO:00030081850.012
regulation of intracellular protein transportGO:003315730.012
single organism cellular localizationGO:1902580460.012
hormone secretionGO:004687920.012
pancreas developmentGO:0031016840.012
long chain fatty acid metabolic processGO:000167610.012
cellular response to external stimulusGO:007149620.012
meiotic nuclear divisionGO:000712640.011
muscle structure developmentGO:00610611960.011
regulation of cellular component movementGO:0051270550.011
negative regulation of nucleobase containing compound metabolic processGO:0045934590.011
small molecule metabolic processGO:0044281770.011
positive regulation of macromolecule biosynthetic processGO:0010557590.011
angiogenesisGO:00015251580.011
regulation of cytoplasmic transportGO:190364940.011
regulation of myotube differentiationGO:001083020.011
otic vesicle morphogenesisGO:0071600340.011
negative regulation of multi organism processGO:004390130.011
regulation of synaptic plasticityGO:004816710.011
immune effector processGO:0002252230.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.011
reactive oxygen species biosynthetic processGO:190340910.011
negative chemotaxisGO:005091910.011
embryonic appendage morphogenesisGO:0035113300.011
response to woundingGO:00096111160.011
regulation of inflammatory responseGO:005072720.011
organelle organizationGO:00069962270.011
regulation of cell activationGO:005086510.011
g1 s transition of mitotic cell cycleGO:000008210.011
positive regulation of catabolic processGO:000989640.011
positive regulation of cellular amine metabolic processGO:003324000.011
establishment of blood brain barrierGO:006085620.011
positive regulation of cellular component biogenesisGO:004408930.011
regulation of blood vessel sizeGO:005088020.011
macromolecular complex disassemblyGO:003298410.011
stem cell developmentGO:0048864820.010
neurotransmitter transportGO:000683620.010
regulation of intracellular signal transductionGO:1902531570.010
nephron morphogenesisGO:007202820.010
peptide transportGO:001583310.010
negative regulation of cytokine productionGO:000181810.010
cell cell recognitionGO:000998810.010
metencephalon developmentGO:0022037270.010
synaptic target recognitionGO:000803910.010
neural crest cell migrationGO:0001755420.010
heart loopingGO:0001947940.010
golgi vesicle transportGO:004819330.010
regulation of cell projection organizationGO:0031344440.010
cellular response to nutrient levelsGO:003166920.010
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.010
stem cell divisionGO:001714510.010
eye photoreceptor cell differentiationGO:0001754450.010
cellular protein modification processGO:00064641000.010
negative regulation of map kinase activityGO:004340720.010
lateral inhibitionGO:004633110.010
negative regulation of nucleic acid templated transcriptionGO:1903507450.010
positive regulation of biosynthetic processGO:0009891680.010

irx5b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.075
nervous system diseaseDOID:86300.053
sensory system diseaseDOID:005015500.039
eye diseaseDOID:561400.027
eye and adnexa diseaseDOID:149200.027
retinal diseaseDOID:567900.010