Danio rerio

21 known processes

opa1

optic atrophy 1 (human)

(Aliases: wu:fb77a10,zgc:92092,fb77a10,wu:fk62d06)

opa1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.091
larval developmentGO:000216420.088
Worm
negative regulation of biological processGO:00485193040.070
Mouse
nitrogen compound metabolic processGO:00068073190.069
tube morphogenesisGO:00352393490.062
Mouse
regulation of establishment of protein localizationGO:007020140.058
regulation of response to stimulusGO:00485832690.055
Mouse
regulation of biological qualityGO:00650082630.053
chordate embryonic developmentGO:00430092710.051
Mouse
brain developmentGO:00074202930.051
stem cell maintenanceGO:001982740.047
central nervous system developmentGO:00074173870.045
organonitrogen compound metabolic processGO:1901564740.045
multicellular organism growthGO:003526440.044
Worm
cell surface receptor signaling pathwayGO:00071663250.044
regulation of reproductive processGO:200024140.043
heterocycle metabolic processGO:00464832900.043
response to glucocorticoidGO:005138410.043
regulation of multicellular organism growthGO:004001440.040
Worm
regulation of macromolecule metabolic processGO:00602553170.039
regulation of multicellular organismal processGO:00512392770.039
Worm
regulation of metabolic processGO:00192223590.039
g1 s transition of mitotic cell cycleGO:000008210.038
protein localization to plasma membraneGO:007265910.038
organic substance biosynthetic processGO:19015762890.038
regulation of protein complex assemblyGO:004325430.038
cellular response to external stimulusGO:007149620.038
establishment of protein localization to plasma membraneGO:009000210.037
adult behaviorGO:003053420.037
pericardium developmentGO:006003910.036
positive regulation of transportGO:005105020.036
cell cycle g1 s phase transitionGO:004484310.036
regulation of cellular amino acid metabolic processGO:000652100.036
single organism membrane fusionGO:004480120.035
Mouse Worm
energy reserve metabolic processGO:000611220.035
regulation of gene expressionGO:00104682650.035
digestive tract developmentGO:00485652650.035
regulation of protein transportGO:005122330.033
small molecule metabolic processGO:0044281770.032
cellular nitrogen compound metabolic processGO:00346412900.032
maintenance of locationGO:005123540.031
cellular biosynthetic processGO:00442492860.031
establishment of protein localization to organelleGO:007259440.031
nucleobase containing compound metabolic processGO:00061392740.031
positive regulation of cell adhesionGO:004578510.030
head developmentGO:00603223030.030
gtp catabolic processGO:000618420.030
gastrulationGO:00073692080.030
regulation of meiotic cell cycleGO:005144510.030
cellular response to extracellular stimulusGO:003166820.029
cellular macromolecule metabolic processGO:00442603910.029
negative regulation of small gtpase mediated signal transductionGO:005105810.029
morphogenesis of an epitheliumGO:00020093330.027
Mouse
homeostatic processGO:00425921420.027
negative regulation of response to stimulusGO:00485851040.027
Mouse
organic cyclic compound metabolic processGO:19013603010.026
regulation of cell shapeGO:000836010.026
regulation of cell developmentGO:00602841000.026
neuron differentiationGO:00301823530.026
cellular component morphogenesisGO:00329893360.025
guanosine containing compound metabolic processGO:190106840.025
regulation of cellular metabolic processGO:00313233200.025
regulation of synapse organizationGO:005080730.025
response to chemicalGO:00422213200.025
Worm
regulation of synapse assemblyGO:005196330.025
guanosine containing compound catabolic processGO:190106920.025
negative regulation of protein transportGO:005122430.024
embryonic organ morphogenesisGO:00485622740.024
response to drugGO:004249330.024
neuron developmentGO:00486662620.024
cell migration involved in gastrulationGO:0042074790.023
membrane fusionGO:006102520.023
Mouse Worm
regulation of protein localization to plasma membraneGO:190307610.023
sensory organ developmentGO:00074233930.023
digestive tract morphogenesisGO:00485462310.022
negative regulation of cytokine productionGO:000181810.022
cognitionGO:005089010.022
regulation of cell communicationGO:00106462320.022
Mouse
cellular nitrogen compound biosynthetic processGO:00442712180.022
signal transductionGO:00071654550.022
Mouse
protein secretionGO:000930610.021
embryonic organ developmentGO:00485683810.021
gtp metabolic processGO:004603940.021
generation of neuronsGO:00486993850.021
heterocycle biosynthetic processGO:00181302150.021
single organism metabolic processGO:00447102170.021
cellular amide metabolic processGO:004360340.021
gene expressionGO:00104672520.021
regulation of cellular biosynthetic processGO:00313262450.021
regulation of cytokine productionGO:000181730.021
heart developmentGO:00075073130.021
protein importGO:001703830.020
cellular response to nutrient levelsGO:003166920.020
determination of left right symmetryGO:00073681790.020
oxidation reduction processGO:0055114410.020
stem cell developmentGO:0048864820.020
cellular ketone metabolic processGO:0042180110.020
regulation of establishment of protein localization to plasma membraneGO:009000310.020
wnt signaling pathwayGO:0016055800.020
biosynthetic processGO:00090582940.020
positive regulation of cellular catabolic processGO:003133130.020
microtubule organizing center organizationGO:003102310.020
centrosome duplicationGO:005129810.020
regulation of blood pressureGO:000821710.019
proteasomal protein catabolic processGO:001049820.019
cellular aromatic compound metabolic processGO:00067252950.019
regulation of cellular ketone metabolic processGO:001056570.019
organic cyclic compound biosynthetic processGO:19013622230.019
negative regulation of nitrogen compound metabolic processGO:0051172590.019
ameboidal type cell migrationGO:00016671430.019
digestive system developmentGO:00551232890.019
germ line stem cell maintenanceGO:003071820.019
localization of cellGO:00516742440.019
angiogenesisGO:00015251580.019
regulation of rho protein signal transductionGO:003502320.019
positive regulation of cell cycleGO:004578730.019
cytoskeleton dependent cytokinesisGO:006164030.019
positive regulation of secretionGO:005104710.019
primary neural tube formationGO:001402010.019
Mouse
gene silencing by mirnaGO:003519530.018
regulation of signalingGO:00230512350.018
Mouse
regulation of cytoplasmic transportGO:190364940.018
regulation of cellular amine metabolic processGO:003323800.018
regulation of nitrogen compound metabolic processGO:00511712510.018
cellular amine metabolic processGO:004410620.018
cellular response to radiationGO:007147840.018
phagocytosisGO:000690930.018
nucleobase containing compound biosynthetic processGO:00346542050.018
regulation of peptidyl tyrosine phosphorylationGO:005073010.018
regulation of bindingGO:005109830.018
ras protein signal transductionGO:000726570.018
amine metabolic processGO:000930820.018
ubiquitin dependent protein catabolic processGO:000651130.017
nucleic acid templated transcriptionGO:00976591810.017
cellular component disassemblyGO:002241110.017
cell projection assemblyGO:0030031640.017
regulation of inflammatory responseGO:005072720.017
sensory organ morphogenesisGO:00905962000.017
meiotic cell cycle processGO:190304630.017
positive regulation of secretion by cellGO:190353210.017
cellular component biogenesisGO:00440851780.017
energy homeostasisGO:009700930.017
growthGO:00400071740.017
Worm
protein polymerizationGO:005125840.017
regulation of primary metabolic processGO:00800903110.017
multicellular organismal metabolic processGO:004423620.017
single organism organelle organizationGO:19025891990.017
cell projection morphogenesisGO:00488582440.017
mrna cleavage involved in gene silencing by mirnaGO:003527910.017
nuclear transportGO:005116940.017
vasculature developmentGO:00019442780.017
locomotionGO:00400113130.016
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.016
embryo development ending in birth or egg hatchingGO:00097922710.016
Mouse Worm
multi organism processGO:00517041340.016
negative regulation of ras protein signal transductionGO:004658010.016
cell morphogenesis involved in differentiationGO:00009041950.016
nucleocytoplasmic transportGO:000691340.016
mitochondrion organizationGO:000700540.016
cell migrationGO:00164772370.016
positive regulation of camp biosynthetic processGO:003081920.016
aromatic compound biosynthetic processGO:00194382170.016
protein metabolic processGO:00195381830.016
Worm
pericardium morphogenesisGO:000334410.015
morphogenesis of an epithelial sheetGO:0002011490.015
protein acetylationGO:000647320.015
response to stressGO:00069502630.015
Mouse Worm
cell motilityGO:00488702440.015
organic acid metabolic processGO:0006082310.015
cell projection organizationGO:00300302840.015
centrosome cycleGO:000709810.015
developmental growth involved in morphogenesisGO:0060560860.015
rna metabolic processGO:00160702190.015
response to corticosteroidGO:003196010.015
striated muscle tissue developmentGO:00147061100.015
rna localizationGO:000640340.015
cellular amino acid metabolic processGO:000652070.015
cellular component assemblyGO:00226071700.015
exocytosisGO:000688710.015
regulation of microtubule cytoskeleton organizationGO:007050730.015
positive regulation of catabolic processGO:000989640.015
blood vessel developmentGO:00015682460.015
cell part morphogenesisGO:00329902460.015
organonitrogen compound biosynthetic processGO:1901566470.015
protein localization to nucleusGO:003450430.015
regulation of purine nucleotide catabolic processGO:003312120.014
negative regulation of macromolecule metabolic processGO:0010605760.014
single organism biosynthetic processGO:0044711710.014
response to uvGO:000941130.014
negative regulation of secretionGO:005104820.014
regulation of synaptic plasticityGO:004816710.014
atp catabolic processGO:000620040.014
cell morphogenesisGO:00009022890.014
gene silencing by rnaGO:003104740.014
regulation of intracellular protein transportGO:003315730.014
rna 3 end processingGO:003112320.014
positive regulation of neuron deathGO:190121610.014
cellular macromolecule biosynthetic processGO:00346452240.014
muscle structure developmentGO:00610611960.014
phosphate containing compound metabolic processGO:00067961080.014
meiotic nuclear divisionGO:000712640.014
oxoacid metabolic processGO:0043436310.014
negative regulation of metabolic processGO:0009892860.014
regulation of signal transductionGO:00099662250.014
Mouse
response to external stimulusGO:00096052640.014
positive regulation of cellular amino acid metabolic processGO:004576400.014
single organism nuclear importGO:190259330.014
cell morphogenesis involved in neuron differentiationGO:00486671630.014
positive regulation of nucleotide catabolic processGO:003081310.014
regulation of cellular macromolecule biosynthetic processGO:20001122220.014
regulation of gtpase activityGO:004308720.014
peptide transportGO:001583310.014
axonogenesisGO:00074091520.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
mesenchymal cell developmentGO:0014031780.013
regulation of protein import into nucleusGO:004230620.013
regulation of gtp catabolic processGO:003312420.013
negative regulation of reproductive processGO:200024230.013
phosphorus metabolic processGO:00067931090.013
regulation of nucleic acid templated transcriptionGO:19035062130.013
macromolecular complex disassemblyGO:003298410.013
peptidyl serine phosphorylationGO:001810510.013
cellular localizationGO:0051641970.013
nuclear importGO:005117030.013
i kappab kinase nf kappab signalingGO:000724940.013
negative regulation of protein kinase activityGO:000646940.013
regulation of protein targetingGO:190353320.013
cell cycle arrestGO:000705010.013
skeletal system developmentGO:00015011810.013
regulation of metal ion transportGO:001095940.013
cellular component movementGO:00069283350.012
developmental maturationGO:0021700340.012
response to nutrientGO:000758430.012
carboxylic acid metabolic processGO:0019752220.012
positive regulation of nitrogen compound metabolic processGO:0051173690.012
post embryonic organ developmentGO:004856940.012
negative regulation of cellular processGO:00485232830.012
Mouse
negative regulation of protein complex assemblyGO:003133310.012
negative regulation of protein phosphorylationGO:000193340.012
synaptic growth at neuromuscular junctionGO:005112420.012
protein import into nucleusGO:000660630.012
negative regulation of intracellular transportGO:003238730.012
positive regulation of purine nucleotide catabolic processGO:003312310.012
chemosensory behaviorGO:000763510.012
compound eye developmentGO:004874920.012
protein targeting to nucleusGO:004474430.012
small gtpase mediated signal transductionGO:000726480.012
endosomal transportGO:001619720.012
negative regulation of defense responseGO:003134820.012
cellular extravasationGO:004512310.012
positive regulation of nucleoside metabolic processGO:004597910.012
system processGO:00030081850.012
negative regulation of protein localization to nucleusGO:190018120.012
proteolysis involved in cellular protein catabolic processGO:005160330.012
protein complex disassemblyGO:004324110.012
organelle fusionGO:004828430.012
Mouse Worm
cellular protein catabolic processGO:004425740.012
regulation of nucleoside metabolic processGO:000911820.012
peptide metabolic processGO:000651810.012
carbohydrate homeostasisGO:003350010.012
positive regulation of protein complex assemblyGO:003133420.012
positive regulation of cellular processGO:00485222010.012
positive regulation of gtp catabolic processGO:003312610.012
rho protein signal transductionGO:000726650.012
cell substrate adhesionGO:003158940.012
regulation of protein localization to nucleusGO:190018020.012
regulation of nucleocytoplasmic transportGO:004682220.012
positive regulation of biological processGO:00485182530.011
Worm
neuron projection developmentGO:00311751800.011
cellular response to starvationGO:000926710.011
cell matrix adhesionGO:000716040.011
centrosome organizationGO:005129710.011
alcohol biosynthetic processGO:004616520.011
transcription from rna polymerase ii promoterGO:0006366800.011
regulation of developmental processGO:00507932470.011
Worm
peptidyl serine modificationGO:001820920.011
carbohydrate derivative metabolic processGO:1901135610.011
positive regulation of cell substrate adhesionGO:001081110.011
response to endogenous stimulusGO:0009719830.011
regulation of mitochondrion organizationGO:001082110.011
Mouse
neuron projection morphogenesisGO:00488121610.011
gland developmentGO:00487321430.011
mitotic dna damage checkpointGO:004477340.011
extrinsic apoptotic signaling pathwayGO:009719130.011
camera type eye developmentGO:00430102220.011
amide biosynthetic processGO:004360410.011
intracellular mrna localizationGO:000829810.011
protein acylationGO:004354330.011
single organism transportGO:00447652060.011
multicellular organismal macromolecule metabolic processGO:004425920.011
negative regulation of catabolic processGO:000989530.011
regulation of cell activationGO:005086510.011
regulation of cellular extravasationGO:000269110.011
organism emergence from protective structureGO:007168440.011
peptidyl lysine acetylationGO:001839420.011
immune system processGO:00023762410.011
regulation of nucleotide catabolic processGO:003081120.011
phagocytosis engulfmentGO:000691110.011
ribonucleoside monophosphate catabolic processGO:000915840.011
lymphocyte proliferationGO:004665110.011
positive regulation of protein polymerizationGO:003227320.011
ribonucleotide metabolic processGO:0009259270.011
locomotor rhythmGO:004547530.011
determination of bilateral symmetryGO:00098552040.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.011
cytokinesisGO:000091030.011
chemotaxisGO:00069351040.011
regulation of autophagyGO:001050630.011
mitotic cytokinesisGO:000028130.011
organelle organizationGO:00069962270.011
negative regulation of dna metabolic processGO:005105340.011
establishment of localization in cellGO:0051649770.010
lateral inhibitionGO:004633110.010
regulation of neural precursor cell proliferationGO:200017730.010
cellular response to chemical stimulusGO:00708871570.010
regulation of biosynthetic processGO:00098892500.010
axon developmentGO:00615641660.010
regulation of mrna processingGO:005068430.010
negative regulation of intracellular protein transportGO:009031730.010
eye developmentGO:00016542770.010
macromolecule modificationGO:00434121110.010
regulation of i kappab kinase nf kappab signalingGO:004312240.010
tube closureGO:006060610.010
Mouse
purine nucleoside monophosphate catabolic processGO:000912840.010
negative regulation of cellular catabolic processGO:003133030.010
regulation of cellular component organizationGO:0051128860.010
Mouse
response to ketoneGO:190165410.010
hormone secretionGO:004687920.010
transcription dna templatedGO:00063511810.010
negative regulation of signal transductionGO:0009968940.010
Mouse
tissue remodelingGO:004877140.010
negative regulation of multi organism processGO:004390130.010
negative regulation of cytoplasmic transportGO:190365020.010
rna biosynthetic processGO:00327741810.010
organic substance transportGO:0071702580.010
macromolecule biosynthetic processGO:00090592270.010
positive regulation of cell deathGO:0010942290.010
positive regulation of gtpase activityGO:004354710.010
regulation of nucleobase containing compound metabolic processGO:00192192500.010
negative regulation of multicellular organismal processGO:0051241690.010
regulation of macromolecule biosynthetic processGO:00105562250.010
negative regulation of translationGO:001714810.010

opa1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.038
musculoskeletal system diseaseDOID:1700.016
organ system cancerDOID:005068600.014
cancerDOID:16200.014
disease of cellular proliferationDOID:1456600.014
disease of metabolismDOID:001466700.013
inherited metabolic disorderDOID:65500.010