IMP: Integrative Multi-species Prediction

Danio rerio

33 known processes

itgb1b

integrin, beta 1b

(Aliases: itgb1,cb810)

Ensembl: ENSDARG00000053255
Entrez: 570216
ZFIN: ZDB-GENE-030909-10
UniProtKB: Q3YAA0

Process Predictions
Disease Predictions

itgb1b biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cellular extravasation	GO:0045123	1	0.947	Human
actin filament bundle organization	GO:0061572	6	0.917	Fly
cell migration involved in gastrulation	GO:0042074	79	0.905
multicellular organismal metabolic process	GO:0044236	2	0.891	Human
multicellular organismal macromolecule metabolic process	GO:0044259	2	0.887	Human
localization of cell	GO:0051674	244	0.886
negative regulation of small gtpase mediated signal transduction	GO:0051058	1	0.874	Mouse
larval heart development	GO:0007508	2	0.845	Fly
muscle attachment	GO:0016203	9	0.828	Fly
locomotion	GO:0040011	313	0.824
ameboidal type cell migration	GO:0001667	143	0.820
collagen metabolic process	GO:0032963	2	0.811	Human
regulation of biological quality	GO:0065008	263	0.792	Fly
response to external stimulus	GO:0009605	264	0.767	Fly
cell morphogenesis involved in neuron differentiation	GO:0048667	163	0.760	Mouse Fly
cell part morphogenesis	GO:0032990	246	0.745	Mouse Fly
determination of bilateral symmetry	GO:0009855	204	0.744
negative regulation of rho protein signal transduction	GO:0035024	1	0.743	Mouse
cell migration	GO:0016477	237	0.729
regulation of collagen metabolic process	GO:0010712	2	0.724	Human
cell motility	GO:0048870	244	0.723
cell morphogenesis	GO:0000902	289	0.665	Mouse Fly
regulation of multicellular organismal metabolic process	GO:0044246	2	0.645	Human
vasculature development	GO:0001944	278	0.634	Mouse
cell projection organization	GO:0030030	284	0.622	Mouse Fly
larval development	GO:0002164	2	0.620	Fly
pericardium morphogenesis	GO:0003344	1	0.612	Fly
taxis	GO:0042330	109	0.605	Fly
regulation of multicellular organismal process	GO:0051239	277	0.589	Human
signal transduction	GO:0007165	455	0.588	Human Mouse
cellular component movement	GO:0006928	335	0.588
tissue migration	GO:0090130	37	0.584	Mouse Fly
neuron projection morphogenesis	GO:0048812	161	0.557	Mouse Fly
stress fiber assembly	GO:0043149	5	0.551	Fly
single organism localization	GO:1902578	225	0.540	Human
blood vessel morphogenesis	GO:0048514	216	0.537	Mouse
negative regulation of biological process	GO:0048519	304	0.528	Human Mouse Fly
axon development	GO:0061564	166	0.523	Mouse Fly
cellular component morphogenesis	GO:0032989	336	0.515	Mouse Fly
cell surface receptor signaling pathway	GO:0007166	325	0.505	Human
stem cell maintenance	GO:0019827	4	0.505	Fly
actomyosin structure organization	GO:0031032	53	0.504	Mouse Fly
aging	GO:0007568	2	0.501	Fly
cell projection morphogenesis	GO:0048858	244	0.484	Mouse Fly
cognition	GO:0050890	1	0.484	Mouse
response to vitamin	GO:0033273	3	0.476
heart development	GO:0007507	313	0.472	Mouse Fly
response to chemical	GO:0042221	320	0.471	Fly
kupffer s vesicle development	GO:0070121	50	0.466
tube morphogenesis	GO:0035239	349	0.461
blood vessel development	GO:0001568	246	0.461	Mouse
angiogenesis	GO:0001525	158	0.459	Mouse
developmental growth	GO:0048589	166	0.449	Mouse Fly
response to stress	GO:0006950	263	0.441
regulation of localization	GO:0032879	104	0.436	Human Fly
post embryonic organ development	GO:0048569	4	0.428	Fly
regulation of cell differentiation	GO:0045595	142	0.421	Mouse Fly
germ line stem cell maintenance	GO:0030718	2	0.387	Fly
single organism cell adhesion	GO:0098602	29	0.384	Human
neuron projection development	GO:0031175	180	0.377	Mouse Fly
small gtpase mediated signal transduction	GO:0007264	8	0.369	Mouse
regulation of signaling	GO:0023051	235	0.365	Mouse
positive regulation of biological process	GO:0048518	253	0.361	Human Mouse Worm
sensory perception of chemical stimulus	GO:0007606	3	0.358	Fly
regulation of signal transduction	GO:0009966	225	0.357	Mouse
negative regulation of ras protein signal transduction	GO:0046580	1	0.338	Mouse
response to organic cyclic compound	GO:0014070	51	0.338
mesoderm morphogenesis	GO:0048332	51	0.333	Human
single organism transport	GO:0044765	206	0.305
regulation of response to stimulus	GO:0048583	269	0.305	Mouse
axon guidance	GO:0007411	86	0.299	Fly
digestive system development	GO:0055123	289	0.294
axonogenesis	GO:0007409	152	0.292	Mouse Fly
digestive tract development	GO:0048565	265	0.291
regulation of neuron differentiation	GO:0045664	56	0.284
sprouting angiogenesis	GO:0002040	53	0.281	Mouse
regulation of rho protein signal transduction	GO:0035023	2	0.275	Mouse
cell death	GO:0008219	121	0.275	Human Worm
cellular component assembly	GO:0022607	170	0.270	Mouse Fly
gastrulation	GO:0007369	208	0.269
negative regulation of cell projection organization	GO:0031345	9	0.265
regulation of apoptotic process	GO:0042981	98	0.260	Human
cell migration involved in sprouting angiogenesis	GO:0002042	8	0.257	Mouse
central nervous system development	GO:0007417	387	0.254	Mouse Fly
regulation of cell communication	GO:0010646	232	0.246	Mouse
cell adhesion mediated by integrin	GO:0033627	1	0.246	Human
specification of symmetry	GO:0009799	204	0.242
death	GO:0016265	121	0.241	Human Worm
behavior	GO:0007610	74	0.240	Mouse
developmental growth involved in morphogenesis	GO:0060560	86	0.240	Mouse Fly
regulation of establishment of protein localization	GO:0070201	4	0.239	Human
regulation of multicellular organismal development	GO:2000026	223	0.239
regulation of anatomical structure morphogenesis	GO:0022603	130	0.232	Fly
regulation of cell morphogenesis	GO:0022604	42	0.232	Fly
response to light stimulus	GO:0009416	46	0.229	Mouse
single organism metabolic process	GO:0044710	217	0.229	Human
morphogenesis of an epithelium	GO:0002009	333	0.228	Fly
generation of neurons	GO:0048699	385	0.227	Mouse Fly
organelle assembly	GO:0070925	110	0.219	Mouse
cell substrate adhesion	GO:0031589	4	0.216	Human Mouse Fly
positive regulation of map kinase activity	GO:0043406	3	0.210
mesoderm development	GO:0007498	88	0.208	Human
sensory perception	GO:0007600	39	0.207	Fly
cell projection assembly	GO:0030031	64	0.206	Fly
negative regulation of response to stimulus	GO:0048585	104	0.201	Mouse
neuron development	GO:0048666	262	0.200	Mouse Fly
phosphate containing compound metabolic process	GO:0006796	108	0.197
response to organic substance	GO:0010033	153	0.197
biological adhesion	GO:0022610	40	0.192	Human Mouse Fly
apoptotic process	GO:0006915	116	0.191	Human Worm
establishment of localization	GO:0051234	244	0.189	Human
cellular response to organic cyclic compound	GO:0071407	38	0.187
system process	GO:0003008	185	0.184	Mouse Worm Fly
cell proliferation	GO:0008283	80	0.183	Mouse
positive regulation of cell proliferation	GO:0008284	15	0.182	Mouse
germ cell migration	GO:0008354	8	0.177	Mouse
muscle structure development	GO:0061061	196	0.172	Mouse Worm Fly
response to nutrient	GO:0007584	3	0.172
single organismal cell cell adhesion	GO:0016337	29	0.171	Human
negative regulation of cellular process	GO:0048523	283	0.167	Human Mouse Fly
cell fate commitment	GO:0045165	99	0.166	Mouse
chemotaxis	GO:0006935	104	0.156	Fly
response to radiation	GO:0009314	51	0.156	Mouse
transport	GO:0006810	220	0.154
muscle organ development	GO:0007517	101	0.148	Fly
regulation of cell shape	GO:0008360	1	0.147	Fly
rho protein signal transduction	GO:0007266	5	0.146	Mouse
regulation of cell adhesion	GO:0030155	15	0.144
axon extension	GO:0048675	45	0.144	Mouse
immune system process	GO:0002376	241	0.144	Human Fly
growth	GO:0040007	174	0.143	Mouse Fly
determination of left right symmetry	GO:0007368	179	0.143
cytoskeleton organization	GO:0007010	96	0.141	Mouse Fly
regulation of developmental process	GO:0050793	247	0.140	Mouse Fly
cell migration in hindbrain	GO:0021535	7	0.140	Mouse
organic cyclic compound biosynthetic process	GO:1901362	223	0.138
heart morphogenesis	GO:0003007	156	0.138
reproduction	GO:0000003	40	0.137	Mouse Worm Fly
positive regulation of cell adhesion	GO:0045785	1	0.134
embryonic organ morphogenesis	GO:0048562	274	0.133
cell cycle g1 s phase transition	GO:0044843	1	0.132	Mouse
regulation of metabolic process	GO:0019222	359	0.128	Human
phosphorus metabolic process	GO:0006793	109	0.128
cell growth	GO:0016049	57	0.121	Mouse
multicellular organism reproduction	GO:0032504	35	0.121	Mouse Fly
nitric oxide metabolic process	GO:0046209	2	0.120
protein modification process	GO:0036211	100	0.118
cellular response to nutrient levels	GO:0031669	2	0.118
maintenance of location	GO:0051235	4	0.117
regulation of neuron projection development	GO:0010975	40	0.116
cellular response to chemical stimulus	GO:0070887	157	0.113
single organism organelle organization	GO:1902589	199	0.113	Mouse Fly
epithelium migration	GO:0090132	25	0.112	Mouse Fly
positive regulation of cellular component movement	GO:0051272	11	0.112
cellular nitrogen compound biosynthetic process	GO:0044271	218	0.112
blood vessel endothelial cell migration	GO:0043534	18	0.109	Mouse
regulation of cellular component movement	GO:0051270	55	0.107	Fly
positive regulation of programmed cell death	GO:0043068	29	0.106	Human
cardiac muscle cell differentiation	GO:0055007	30	0.105	Mouse
g1 s transition of mitotic cell cycle	GO:0000082	1	0.105	Mouse
embryo development ending in birth or egg hatching	GO:0009792	271	0.103	Mouse Worm Fly
negative regulation of apoptotic process	GO:0043066	55	0.103	Human
cell junction organization	GO:0034330	11	0.103
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.102
regulation of protein targeting	GO:1903533	2	0.102
embryonic organ development	GO:0048568	381	0.102	Fly
programmed cell death	GO:0012501	119	0.101	Human Worm
response to abiotic stimulus	GO:0009628	122	0.101	Mouse
dendrite development	GO:0016358	9	0.101	Mouse
skeletal muscle organ development	GO:0060538	78	0.100	Fly
positive regulation of cell motility	GO:2000147	11	0.099
striated muscle cell differentiation	GO:0051146	129	0.099	Mouse
cell migration involved in heart development	GO:0060973	22	0.098
morphogenesis of an epithelial sheet	GO:0002011	49	0.098	Fly
muscle tissue development	GO:0060537	110	0.098	Mouse
protein metabolic process	GO:0019538	183	0.097	Worm
neuron differentiation	GO:0030182	353	0.097	Mouse Fly
regulation of cell death	GO:0010941	103	0.095	Human
cellular ketone metabolic process	GO:0042180	11	0.095
macromolecule catabolic process	GO:0009057	15	0.094	Worm
regulation of locomotion	GO:0040012	55	0.094	Worm Fly
cellular component biogenesis	GO:0044085	178	0.094	Mouse Fly
chordate embryonic development	GO:0043009	271	0.093	Mouse
regulation of cell proliferation	GO:0042127	37	0.093	Mouse
negative regulation of cell death	GO:0060548	60	0.093	Human
cell adhesion	GO:0007155	40	0.092	Human Mouse Fly
regulation of cell substrate adhesion	GO:0010810	1	0.090
positive regulation of locomotion	GO:0040017	14	0.090	Worm
sexual reproduction	GO:0019953	36	0.090	Mouse Fly
epithelial cell migration	GO:0010631	25	0.089	Mouse Fly
regulation of cell projection organization	GO:0031344	44	0.089
muscle cell development	GO:0055001	115	0.086	Mouse Worm
cellular macromolecule metabolic process	GO:0044260	391	0.086
stem cell development	GO:0048864	82	0.086	Fly
exocrine system development	GO:0035272	28	0.085	Fly
nucleocytoplasmic transport	GO:0006913	4	0.085
cellular amino acid metabolic process	GO:0006520	7	0.085
cardiocyte differentiation	GO:0035051	44	0.084	Mouse
ras protein signal transduction	GO:0007265	7	0.084	Mouse
cardiac muscle tissue development	GO:0048738	48	0.083	Mouse
actin filament based process	GO:0030029	64	0.081	Mouse Fly
striated muscle cell development	GO:0055002	108	0.081	Mouse
myofibril assembly	GO:0030239	48	0.081	Mouse
anatomical structure homeostasis	GO:0060249	36	0.080	Fly
regulation of cellular component organization	GO:0051128	86	0.080	Human Fly
head development	GO:0060322	303	0.079	Mouse
establishment of protein localization to organelle	GO:0072594	4	0.079
response to lipid	GO:0033993	60	0.078
regulation of neurogenesis	GO:0050767	87	0.078
oxoacid metabolic process	GO:0043436	31	0.075
nucleobase containing compound biosynthetic process	GO:0034654	205	0.075
negative regulation of signaling	GO:0023057	96	0.075	Mouse
digestive tract morphogenesis	GO:0048546	231	0.075
actin filament organization	GO:0007015	15	0.074	Fly
calcium ion homeostasis	GO:0055074	19	0.074
regulation of cytokine production	GO:0001817	3	0.074
regulation of tube size	GO:0035150	2	0.073
apical junction assembly	GO:0043297	1	0.073
body morphogenesis	GO:0010171	16	0.072	Worm
sarcomere organization	GO:0045214	26	0.072	Mouse
developmental cell growth	GO:0048588	52	0.071	Mouse
positive regulation of cell migration	GO:0030335	11	0.071
organic substance transport	GO:0071702	58	0.071
neuroblast proliferation	GO:0007405	2	0.071
single organism reproductive process	GO:0044702	40	0.070	Mouse Fly
regulation of programmed cell death	GO:0043067	101	0.069	Human
homeostatic process	GO:0042592	142	0.069	Fly
biosynthetic process	GO:0009058	294	0.068
positive regulation of cell differentiation	GO:0045597	30	0.068
carbohydrate biosynthetic process	GO:0016051	1	0.067
establishment of protein localization to plasma membrane	GO:0090002	1	0.066	Human
multicellular organismal reproductive process	GO:0048609	35	0.065	Mouse Fly
catabolic process	GO:0009056	32	0.064	Human Worm
lipid storage	GO:0019915	1	0.063
blood circulation	GO:0008015	87	0.063
regulation of macromolecule metabolic process	GO:0060255	317	0.062	Human
macromolecule localization	GO:0033036	54	0.062	Human
chemical homeostasis	GO:0048878	49	0.062
positive regulation of catabolic process	GO:0009896	4	0.061
organic substance catabolic process	GO:1901575	28	0.060	Worm
regulation of cellular amino acid metabolic process	GO:0006521	0	0.060
extrinsic apoptotic signaling pathway	GO:0097191	3	0.060
regulation of macromolecule biosynthetic process	GO:0010556	225	0.059
membrane organization	GO:0061024	21	0.059	Human
skeletal system development	GO:0001501	181	0.058
regulation of protein metabolic process	GO:0051246	56	0.058
cellular amine metabolic process	GO:0044106	2	0.057
regulation of cell motility	GO:2000145	46	0.057	Fly
regeneration	GO:0031099	91	0.056
regulation of cytoskeleton organization	GO:0051493	11	0.056	Fly
positive regulation of cellular metabolic process	GO:0031325	94	0.055
stem cell differentiation	GO:0048863	117	0.055	Fly
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	1	0.055
protein targeting to nucleus	GO:0044744	3	0.053
cellular biosynthetic process	GO:0044249	286	0.053
macromolecular complex subunit organization	GO:0043933	74	0.052	Fly
positive regulation of developmental process	GO:0051094	50	0.052
actin cytoskeleton organization	GO:0030036	63	0.051	Mouse Fly
cellular process involved in reproduction in multicellular organism	GO:0022412	28	0.051	Mouse Fly
tissue homeostasis	GO:0001894	25	0.051	Fly
positive regulation of protein kinase b signaling	GO:0051897	1	0.050
neuron projection extension	GO:1990138	45	0.050	Mouse
cellular protein metabolic process	GO:0044267	129	0.050
phosphorylation	GO:0016310	69	0.050
divalent inorganic cation homeostasis	GO:0072507	22	0.050
cell substrate junction assembly	GO:0007044	2	0.049
regionalization	GO:0003002	274	0.048
immune system development	GO:0002520	191	0.048	Fly
response to drug	GO:0042493	3	0.048
regulation of organelle organization	GO:0033043	29	0.048	Fly
regulation of protein transport	GO:0051223	3	0.048
heterocycle metabolic process	GO:0046483	290	0.048
g protein coupled receptor signaling pathway	GO:0007186	74	0.047
cell matrix adhesion	GO:0007160	4	0.047	Human Mouse
positive regulation of response to stimulus	GO:0048584	80	0.047
negative regulation of cell communication	GO:0010648	96	0.046	Mouse
cellular carbohydrate metabolic process	GO:0044262	4	0.046
negative regulation of signal transduction	GO:0009968	94	0.046	Mouse
regulation of primary metabolic process	GO:0080090	311	0.046
embryonic heart tube development	GO:0035050	133	0.045
multicellular organism growth	GO:0035264	4	0.045
neurological system process	GO:0050877	62	0.045	Mouse Fly
establishment of localization in cell	GO:0051649	77	0.045
regulation of vesicle mediated transport	GO:0060627	9	0.045
actin filament bundle assembly	GO:0051017	6	0.045	Fly
intracellular receptor signaling pathway	GO:0030522	30	0.044
positive regulation of transport	GO:0051050	2	0.044
nuclear import	GO:0051170	3	0.043
regulation of muscle contraction	GO:0006937	3	0.043
muscle cell differentiation	GO:0042692	139	0.043	Mouse Worm
cellular component assembly involved in morphogenesis	GO:0010927	107	0.043	Mouse
embryonic skeletal system morphogenesis	GO:0048704	93	0.043
organonitrogen compound metabolic process	GO:1901564	74	0.043
striated muscle tissue development	GO:0014706	110	0.042	Mouse
single organism nuclear import	GO:1902593	3	0.042
ion homeostasis	GO:0050801	41	0.042
stem cell division	GO:0017145	1	0.042
positive regulation of erk1 and erk2 cascade	GO:0070374	2	0.042
organic acid metabolic process	GO:0006082	31	0.041
cellular nitrogen compound metabolic process	GO:0034641	290	0.039
muscle system process	GO:0003012	20	0.039	Worm
protein import into nucleus	GO:0006606	3	0.039
negative regulation of locomotion	GO:0040013	18	0.039	Fly
protein localization to plasma membrane	GO:0072659	1	0.039	Human
defense response	GO:0006952	47	0.039
regulation of dna replication	GO:0006275	3	0.039
chromosome organization	GO:0051276	31	0.039
phagocytosis engulfment	GO:0006911	1	0.038
response to wounding	GO:0009611	116	0.038
positive regulation of cell communication	GO:0010647	56	0.038
regulation of rna metabolic process	GO:0051252	224	0.038
multi organism reproductive process	GO:0044703	36	0.037	Mouse Fly
negative regulation of protein transport	GO:0051224	3	0.037
striated muscle contraction	GO:0006941	12	0.037	Worm
oxidation reduction process	GO:0055114	41	0.037
carboxylic acid metabolic process	GO:0019752	22	0.037
positive regulation of multicellular organismal process	GO:0051240	52	0.037
positive regulation of apoptotic process	GO:0043065	29	0.037	Human
cilium morphogenesis	GO:0060271	85	0.037
regulation of nervous system development	GO:0051960	90	0.037
adult behavior	GO:0030534	2	0.037
regulation of cellular amine metabolic process	GO:0033238	0	0.036
positive regulation of cell substrate adhesion	GO:0010811	1	0.036
regulation of cell migration	GO:0030334	40	0.036	Fly
regulation of gene expression	GO:0010468	265	0.036
organic cyclic compound metabolic process	GO:1901360	301	0.036
hemopoiesis	GO:0030097	183	0.035	Fly
regulation of rna biosynthetic process	GO:2001141	213	0.035
tight junction assembly	GO:0070830	1	0.035
nitrogen compound metabolic process	GO:0006807	319	0.035
positive regulation of blood circulation	GO:1903524	2	0.035
regulation of nucleocytoplasmic transport	GO:0046822	2	0.034
rna metabolic process	GO:0016070	219	0.034
regulation of multicellular organism growth	GO:0040014	4	0.034
positive regulation of cellular component organization	GO:0051130	13	0.033	Human
intracellular signal transduction	GO:0035556	85	0.033	Mouse
sensory organ development	GO:0007423	393	0.033
nuclear transport	GO:0051169	4	0.033
connective tissue development	GO:0061448	99	0.033
regulation of blood vessel size	GO:0050880	2	0.033
organelle organization	GO:0006996	227	0.033	Mouse Fly
phagocytosis	GO:0006909	3	0.033
regulation of carbohydrate metabolic process	GO:0006109	4	0.032
hindbrain development	GO:0030902	91	0.032	Mouse
regulation of epithelial cell proliferation	GO:0050678	3	0.032
small molecule metabolic process	GO:0044281	77	0.032
cellular protein modification process	GO:0006464	100	0.032
cellular response to oxygen levels	GO:0071453	1	0.032
regulation of peptidyl tyrosine phosphorylation	GO:0050730	1	0.032
embryonic heart tube morphogenesis	GO:0003143	108	0.032
negative regulation of cell motility	GO:2000146	17	0.032	Fly
leukocyte migration	GO:0050900	15	0.031	Human
epithelial cilium movement	GO:0003351	15	0.031
regulation of cell development	GO:0060284	100	0.031
single organism behavior	GO:0044708	24	0.031	Mouse
negative regulation of developmental process	GO:0051093	65	0.030	Mouse Fly
protein localization	GO:0008104	40	0.030	Human
protein secretion	GO:0009306	1	0.029
collagen biosynthetic process	GO:0032964	2	0.029
protein complex subunit organization	GO:0071822	46	0.029	Fly
neuron projection guidance	GO:0097485	86	0.029	Fly
regulation of dendrite development	GO:0050773	3	0.029
positive regulation of cellular protein metabolic process	GO:0032270	22	0.028
dendrite morphogenesis	GO:0048813	5	0.028	Mouse
cellular response to lipid	GO:0071396	39	0.028
sensory perception of smell	GO:0007608	2	0.028	Fly
positive regulation of macromolecule metabolic process	GO:0010604	93	0.028
cell morphogenesis involved in differentiation	GO:0000904	195	0.028	Mouse Fly
positive regulation of rho protein signal transduction	GO:0035025	0	0.028
regulation of chemotaxis	GO:0050920	18	0.027
epithelial tube morphogenesis	GO:0060562	148	0.027
visual behavior	GO:0007632	10	0.027	Mouse
response to fluid shear stress	GO:0034405	2	0.027
membrane invagination	GO:0010324	1	0.027
regulation of protein localization to plasma membrane	GO:1903076	1	0.027	Human
positive regulation of cellular component biogenesis	GO:0044089	3	0.026
organic substance biosynthetic process	GO:1901576	289	0.026
regulation of behavior	GO:0050795	24	0.026
intracellular transport	GO:0046907	32	0.026
cellular response to vitamin	GO:0071295	1	0.026
cation homeostasis	GO:0055080	33	0.026
negative regulation of cell migration	GO:0030336	17	0.026	Fly
regulation of blood circulation	GO:1903522	32	0.025
multicellular organismal homeostasis	GO:0048871	29	0.025	Fly
cell cell junction organization	GO:0045216	10	0.025
multi organism process	GO:0051704	134	0.025	Mouse Fly
regulation of cellular ketone metabolic process	GO:0010565	7	0.025
regulation of actin cytoskeleton organization	GO:0032956	8	0.025	Fly
erk1 and erk2 cascade	GO:0070371	4	0.025
amine metabolic process	GO:0009308	2	0.025
rna biosynthetic process	GO:0032774	181	0.024
cation transport	GO:0006812	81	0.024
cell cycle process	GO:0022402	53	0.024	Mouse
lipid metabolic process	GO:0006629	52	0.024
positive regulation of small gtpase mediated signal transduction	GO:0051057	1	0.024
wound healing	GO:0042060	90	0.024
regulation of stem cell proliferation	GO:0072091	2	0.024
cellular response to radiation	GO:0071478	4	0.024
cellular response to stress	GO:0033554	62	0.024
cell cycle	GO:0007049	93	0.024	Mouse
positive regulation of metabolic process	GO:0009893	108	0.024
cartilage development	GO:0051216	96	0.024
negative regulation of intracellular signal transduction	GO:1902532	22	0.023	Mouse
response to hormone	GO:0009725	48	0.023
nucleic acid metabolic process	GO:0090304	244	0.023
regulation of biosynthetic process	GO:0009889	250	0.023
positive regulation of cellular catabolic process	GO:0031331	3	0.023
positive regulation of cell cycle	GO:0045787	3	0.023
regulation of transcription dna templated	GO:0006355	213	0.023
regulation of leukocyte mediated immunity	GO:0002703	1	0.023
macromolecule modification	GO:0043412	111	0.022
alcohol biosynthetic process	GO:0046165	2	0.022
positive regulation of stem cell proliferation	GO:2000648	1	0.022
heart looping	GO:0001947	94	0.022
endothelial cell migration	GO:0043542	19	0.022	Mouse
cell cell junction assembly	GO:0007043	5	0.022
regulation of cellular component biogenesis	GO:0044087	12	0.022	Fly
regulation of cellular protein metabolic process	GO:0032268	52	0.022
b cell activation	GO:0042113	2	0.021
fat soluble vitamin metabolic process	GO:0006775	4	0.021
cellular response to extracellular stimulus	GO:0031668	2	0.021
gamete generation	GO:0007276	33	0.021	Mouse Fly
muscle cell migration	GO:0014812	4	0.021
cellular localization	GO:0051641	97	0.021	Human
determination of heart left right asymmetry	GO:0061371	117	0.020
positive regulation of chromatin modification	GO:1903310	1	0.020
regulation of establishment of protein localization to plasma membrane	GO:0090003	1	0.020	Human
cellular protein catabolic process	GO:0044257	4	0.020
positive regulation of carbohydrate metabolic process	GO:0045913	1	0.020
cellular calcium ion homeostasis	GO:0006874	13	0.020
regulation of protein import into nucleus	GO:0042306	2	0.020
negative regulation of cytoplasmic transport	GO:1903650	2	0.020
regulation of retinoic acid receptor signaling pathway	GO:0048385	5	0.020
regulation of protein localization to nucleus	GO:1900180	2	0.020
positive regulation of cell death	GO:0010942	29	0.019	Human
regulation of actin filament based process	GO:0032970	9	0.019	Fly
positive regulation of cell activation	GO:0050867	1	0.019
embryonic skeletal system development	GO:0048706	97	0.019
cellular response to external stimulus	GO:0071496	2	0.019
epiboly	GO:0090504	41	0.019
negative regulation of neuron differentiation	GO:0045665	10	0.019
regulation of transport	GO:0051049	45	0.019
regulation of response to external stimulus	GO:0032101	31	0.018
heterocycle biosynthetic process	GO:0018130	215	0.018
carbohydrate derivative metabolic process	GO:1901135	61	0.018
negative regulation of cellular component movement	GO:0051271	18	0.018	Fly
nucleobase containing compound metabolic process	GO:0006139	274	0.018
regulation of hormone secretion	GO:0046883	2	0.018
carboxylic acid catabolic process	GO:0046395	3	0.018
liver development	GO:0001889	96	0.018
ion transport	GO:0006811	114	0.018
brain development	GO:0007420	293	0.018	Mouse
positive regulation of secretion	GO:0051047	1	0.017
carbohydrate homeostasis	GO:0033500	1	0.017
negative regulation of neurogenesis	GO:0050768	20	0.017
gland development	GO:0048732	143	0.017	Fly
regulation of cell activation	GO:0050865	1	0.017
negative regulation of translation	GO:0017148	1	0.017
regulation of ras protein signal transduction	GO:0046578	5	0.017	Mouse
internal peptidyl lysine acetylation	GO:0018393	2	0.017
muscle contraction	GO:0006936	18	0.017	Worm
regulation of molecular function	GO:0065009	70	0.016
positive regulation of cellular amine metabolic process	GO:0033240	0	0.016
peptidyl amino acid modification	GO:0018193	16	0.016
regulation of nucleic acid templated transcription	GO:1903506	213	0.016
positive regulation of cytokine production	GO:0001819	2	0.016
positive regulation of neuron projection development	GO:0010976	9	0.016
positive regulation of ras protein signal transduction	GO:0046579	1	0.016
positive regulation of cytosolic calcium ion concentration	GO:0007204	4	0.016
regulation of system process	GO:0044057	40	0.016
regulation of intracellular protein transport	GO:0033157	3	0.016
neural precursor cell proliferation	GO:0061351	20	0.016
somatic muscle development	GO:0007525	4	0.016
positive regulation of cellular process	GO:0048522	201	0.016	Human Mouse
positive regulation of signal transduction	GO:0009967	56	0.015
positive regulation of neural precursor cell proliferation	GO:2000179	1	0.015
negative regulation of epithelial cell proliferation	GO:0050680	1	0.015
positive regulation of histone deacetylation	GO:0031065	1	0.015
metal ion homeostasis	GO:0055065	26	0.015
positive regulation of nervous system development	GO:0051962	25	0.015
signal transduction in absence of ligand	GO:0038034	1	0.015
aromatic compound biosynthetic process	GO:0019438	217	0.015
negative regulation of programmed cell death	GO:0043069	58	0.015	Human
positive regulation of nitrogen compound metabolic process	GO:0051173	69	0.015
protein phosphorylation	GO:0006468	47	0.015
adrenal gland development	GO:0030325	10	0.015
transcription from rna polymerase ii promoter	GO:0006366	80	0.015
response to oxygen containing compound	GO:1901700	55	0.015
fin development	GO:0033333	77	0.015
cellular homeostasis	GO:0019725	26	0.015
glucose import	GO:0046323	2	0.014
cellular response to lipopolysaccharide	GO:0071222	3	0.014
cellular response to organic substance	GO:0071310	105	0.014
stem cell proliferation	GO:0072089	4	0.014

itgb1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease	DO term ID	Probability
cancer	DOID:162	0.015
disease of cellular proliferation	DOID:14566	0.015
organ system cancer	DOID:0050686	0.015

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