Danio rerio

79 known processes

smn1

survival motor neuron 1

(Aliases: smn,wu:fa12d01,fa12d01)

smn1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
gene expressionGO:00104672520.314
cellular nitrogen compound metabolic processGO:00346412900.294
cellular aromatic compound metabolic processGO:00067252950.285
larval developmentGO:000216420.262
Worm
nucleic acid templated transcriptionGO:00976591810.214
regulation of gene expressionGO:00104682650.210
rna metabolic processGO:00160702190.203
nucleic acid metabolic processGO:00903042440.191
regulation of metabolic processGO:00192223590.158
regulation of primary metabolic processGO:00800903110.156
negative regulation of gene expressionGO:0010629650.141
negative regulation of biological processGO:00485193040.140
Worm
nucleobase containing compound metabolic processGO:00061392740.136
organic substance biosynthetic processGO:19015762890.134
cellular macromolecule biosynthetic processGO:00346452240.130
cellular macromolecule metabolic processGO:00442603910.122
biosynthetic processGO:00090582940.112
nitrogen compound metabolic processGO:00068073190.097
regulation of transcription dna templatedGO:00063552130.091
regulation of nitrogen compound metabolic processGO:00511712510.088
heterocycle metabolic processGO:00464832900.086
cellular biosynthetic processGO:00442492860.084
nuclear exportGO:005116810.082
establishment of localizationGO:00512342440.082
nucleocytoplasmic transportGO:000691340.080
single organism transportGO:00447652060.077
regulation of biosynthetic processGO:00098892500.075
regulation of cellular metabolic processGO:00313233200.073
establishment of localization in cellGO:0051649770.073
regulation of rna metabolic processGO:00512522240.071
apoptotic processGO:00069151160.071
organic cyclic compound biosynthetic processGO:19013622230.069
rna localizationGO:000640340.068
locomotionGO:00400113130.065
transportGO:00068102200.062
modification dependent macromolecule catabolic processGO:004363230.060
rna biosynthetic processGO:00327741810.060
nuclear transportGO:005116940.059
nuclear importGO:005117030.057
nucleobase containing compound biosynthetic processGO:00346542050.057
protein localization to nucleusGO:003450430.056
regulation of macromolecule metabolic processGO:00602553170.054
embryo development ending in birth or egg hatchingGO:00097922710.053
Worm
programmed cell deathGO:00125011190.051
cellular response to nutrient levelsGO:003166920.051
cell deathGO:00082191210.050
cellular protein catabolic processGO:004425740.050
aromatic compound biosynthetic processGO:00194382170.047
regulation of nucleic acid templated transcriptionGO:19035062130.047
single organism metabolic processGO:00447102170.047
organelle organizationGO:00069962270.045
Mouse Worm
multicellular organism growthGO:003526440.045
cellular response to starvationGO:000926710.044
cellular nitrogen compound biosynthetic processGO:00442712180.044
protein targeting to nucleusGO:004474430.043
cell projection morphogenesisGO:00488582440.043
organic cyclic compound metabolic processGO:19013603010.041
transcription dna templatedGO:00063511810.041
establishment of protein localization to organelleGO:007259440.041
regulation of cellular macromolecule biosynthetic processGO:20001122220.040
negative regulation of nucleic acid templated transcriptionGO:1903507450.040
positive regulation of metabolic processGO:00098931080.039
single organism organelle organizationGO:19025891990.038
Mouse Worm
negative regulation of intracellular transportGO:003238730.037
cellular protein modification processGO:00064641000.037
developmental cell growthGO:0048588520.037
developmental growthGO:00485891660.037
sensory organ developmentGO:00074233930.036
spliceosomal snrnp assemblyGO:000038720.035
macromolecule modificationGO:00434121110.035
central nervous system developmentGO:00074173870.035
cellular process involved in reproduction in multicellular organismGO:0022412280.034
Worm
response to alkaloidGO:004327920.034
regulation of establishment of protein localizationGO:007020140.033
axonogenesisGO:00074091520.033
response to drugGO:004249330.032
negative regulation of macromolecule metabolic processGO:0010605760.031
deathGO:00162651210.031
chromatin modificationGO:0016568210.031
cellular response to extracellular stimulusGO:003166820.031
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.031
regulation of nucleobase containing compound metabolic processGO:00192192500.030
regulation of protein ubiquitinationGO:003139630.030
protein importGO:001703830.030
cell morphogenesis involved in differentiationGO:00009041950.030
agingGO:000756820.030
Worm
protein metabolic processGO:00195381830.029
chromosome organizationGO:0051276310.029
single organism localizationGO:19025782250.029
neuron projection developmentGO:00311751800.029
rna splicingGO:0008380160.028
regulation of rna biosynthetic processGO:20011412130.028
heterocycle biosynthetic processGO:00181302150.027
dicarboxylic acid transportGO:000683510.027
protein import into nucleusGO:000660630.026
blood vessel developmentGO:00015682460.026
regulation of multicellular organismal processGO:00512392770.025
regulation of protein transportGO:005122330.025
regulation of nucleocytoplasmic transportGO:004682220.025
embryonic heart tube morphogenesisGO:00031431080.025
single organism nuclear importGO:190259330.024
regulation of histone methylationGO:003106030.024
regulation of cellular amino acid metabolic processGO:000652100.024
rna 3 end processingGO:003112320.024
adult behaviorGO:003053420.024
regulation of cellular biosynthetic processGO:00313262450.024
response to stressGO:00069502630.023
negative regulation of rna biosynthetic processGO:1902679450.023
positive regulation of chromatin modificationGO:190331010.023
proteolysis involved in cellular protein catabolic processGO:005160330.023
cellular response to external stimulusGO:007149620.023
negative regulation of transcription dna templatedGO:0045892450.023
viral processGO:001603210.022
growthGO:00400071740.022
regulation of protein localization to nucleusGO:190018020.022
positive regulation of cellular amine metabolic processGO:003324000.021
protein modification processGO:00362111000.021
regulation of intracellular protein transportGO:003315730.021
mrna processingGO:0006397140.021
gtp metabolic processGO:004603940.020
rrna catabolic processGO:001607510.020
positive regulation of biological processGO:00485182530.020
Worm
i kappab kinase nf kappab signalingGO:000724940.020
chromatin organizationGO:0006325220.019
cytoplasm organizationGO:000702840.019
cell part morphogenesisGO:00329902460.019
retina development in camera type eyeGO:00600411460.019
neuron projection extensionGO:1990138450.019
eye developmentGO:00016542770.019
regulation of macromolecule biosynthetic processGO:00105562250.019
lateral inhibitionGO:004633110.019
histone demethylationGO:001657720.019
gland developmentGO:00487321430.018
oocyte anterior posterior axis specificationGO:000731440.018
gtp catabolic processGO:000618420.018
positive regulation of histone modificationGO:003105810.018
positive regulation of transportGO:005105020.018
rna export from nucleusGO:000640510.018
maintenance of locationGO:005123540.018
negative regulation of cytoplasmic transportGO:190365020.018
ubiquitin dependent protein catabolic processGO:000651130.018
cellular component morphogenesisGO:00329893360.018
cell projection organizationGO:00300302840.017
negative regulation of rna metabolic processGO:0051253480.017
transcription from rna polymerase ii promoterGO:0006366800.017
keratinocyte differentiationGO:003021600.017
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377100.017
organism emergence from protective structureGO:007168440.017
meiotic chromosome segregationGO:004513230.017
regulation of gene expression epigeneticGO:0040029110.017
positive regulation of epithelial cell proliferationGO:005067910.017
intracellular transportGO:0046907320.017
regulation of cytoplasmic transportGO:190364940.017
dna templated transcription elongationGO:000635430.017
mrna splicing via spliceosomeGO:0000398100.017
cellular amine metabolic processGO:004410620.016
macromolecule biosynthetic processGO:00090592270.016
neuron projection morphogenesisGO:00488121610.016
regulation of protein import into nucleusGO:004230620.016
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.016
positive regulation of catabolic processGO:000989640.016
regulation of multicellular organism growthGO:004001440.016
nucleoside monophosphate catabolic processGO:000912540.016
protein secretionGO:000930610.016
interspecies interaction between organismsGO:004441940.016
response to corticosteroidGO:003196010.016
negative regulation of biosynthetic processGO:0009890550.015
meiotic nuclear divisionGO:000712640.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
guanosine containing compound metabolic processGO:190106840.015
negative regulation of cellular processGO:00485232830.015
Worm
regulation of protein modification by small protein conjugation or removalGO:190332030.014
regulation of heart growthGO:006042020.014
intracellular mrna localizationGO:000829810.014
positive regulation of chromosome organizationGO:200125210.014
sensory perception of chemical stimulusGO:000760630.014
regulation of developmental processGO:00507932470.014
negative regulation of macromolecule biosynthetic processGO:0010558480.014
cell growthGO:0016049570.014
signal transduction by p53 class mediatorGO:0072331130.014
response to abiotic stimulusGO:00096281220.014
negative regulation of metabolic processGO:0009892860.014
positive regulation of cellular catabolic processGO:003133130.014
positive regulation of muscle tissue developmentGO:190186310.014
negative regulation of protein transportGO:005122430.014
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.014
negative regulation of signal transduction by p53 class mediatorGO:190179780.014
transcription elongation from rna polymerase ii promoterGO:000636830.014
translational initiationGO:000641330.014
nucleic acid transportGO:005065720.014
neuron neuron synaptic transmissionGO:000727010.014
regulation of reproductive processGO:200024140.013
maternal determination of anterior posterior axis embryoGO:000835840.013
organelle localizationGO:0051640490.013
cellular component biogenesisGO:00440851780.013
Worm
cellular amino acid metabolic processGO:000652070.013
regulation of meiotic cell cycleGO:005144510.013
Worm
muscle structure developmentGO:00610611960.013
Worm
female gonad developmentGO:000858540.013
symbiosis encompassing mutualism through parasitismGO:004440340.013
macromolecule localizationGO:0033036540.013
autophagyGO:000691440.013
single organism cellular localizationGO:1902580460.013
muscle organ developmentGO:00075171010.013
mitochondrion organizationGO:000700540.013
negative regulation of nitrogen compound metabolic processGO:0051172590.013
multi organism cellular processGO:004476420.013
response to monosaccharideGO:003428430.012
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.012
atp catabolic processGO:000620040.012
pigment granule localizationGO:0051875250.012
proteasomal protein catabolic processGO:001049820.012
cellular response to biotic stimulusGO:007121630.012
anterior posterior pattern specificationGO:00099521520.012
histone lysine demethylationGO:007007620.012
histone lysine methylationGO:0034968120.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
digestive tract developmentGO:00485652650.012
generation of neuronsGO:00486993850.012
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.012
rna transportGO:005065820.012
protein polyubiquitinationGO:000020940.012
signal transductionGO:00071654550.011
regulation of epithelial cell proliferationGO:005067830.011
organic acid metabolic processGO:0006082310.011
regulation of protein catabolic processGO:004217610.011
regulation of protein targetingGO:190353320.011
cellular protein metabolic processGO:00442671290.011
positive regulation of cellular metabolic processGO:0031325940.011
regulation of epithelial to mesenchymal transitionGO:001071730.011
gamete generationGO:0007276330.011
Worm
neuron developmentGO:00486662620.011
pole plasm assemblyGO:000731540.011
organonitrogen compound metabolic processGO:1901564740.011
regulation of gtpase activityGO:004308720.011
guanosine containing compound catabolic processGO:190106920.011
response to glucocorticoidGO:005138410.011
synaptic growth at neuromuscular junctionGO:005112420.011
leukocyte homeostasisGO:000177620.011
organic substance transportGO:0071702580.011
regionalizationGO:00030022740.011
alpha amino acid metabolic processGO:190160530.011
peptidyl lysine acetylationGO:001839420.011
epithelial cell differentiationGO:00308551160.011
heart loopingGO:0001947940.011
macroautophagyGO:001623610.011
mrna transportGO:005102820.011
stem cell proliferationGO:007208940.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
neuron projection guidanceGO:0097485860.010
cellular component disassemblyGO:002241110.010
Mouse
negative regulation of nucleobase containing compound metabolic processGO:0045934590.010
modification dependent protein catabolic processGO:001994130.010
regulation of cell differentiationGO:00455951420.010
hematopoietic or lymphoid organ developmentGO:00485341910.010
regulation of cellular amine metabolic processGO:003323800.010
purine ribonucleoside monophosphate catabolic processGO:000916940.010
vasculature developmentGO:00019442780.010

smn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.025
cancerDOID:16200.025
organ system cancerDOID:005068600.025
cardiomyopathyDOID:005070000.015
disease of anatomical entityDOID:700.015
intrinsic cardiomyopathyDOID:006003600.015
heart diseaseDOID:11400.015
muscular diseaseDOID:008000000.015
cardiovascular system diseaseDOID:128700.015
musculoskeletal system diseaseDOID:1700.015
myopathyDOID:42300.015
muscle tissue diseaseDOID:6600.015
nervous system diseaseDOID:86300.012