Danio rerio

54 known processes

apln

apelin

apln biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular component morphogenesisGO:00329893360.398
regulation of cell communicationGO:00106462320.272
muscle structure developmentGO:00610611960.218
nucleobase containing compound metabolic processGO:00061392740.211
organic cyclic compound metabolic processGO:19013603010.209
muscle tissue developmentGO:00605371100.208
cell surface receptor signaling pathwayGO:00071663250.194
heterocycle metabolic processGO:00464832900.192
embryonic organ developmentGO:00485683810.191
regulation of response to stimulusGO:00485832690.189
digestive system developmentGO:00551232890.175
positive regulation of biological processGO:00485182530.163
embryonic organ morphogenesisGO:00485622740.139
regulation of gene expressionGO:00104682650.138
cell morphogenesis involved in differentiationGO:00009041950.138
negative regulation of biological processGO:00485193040.136
regulation of multicellular organismal processGO:00512392770.132
determination of bilateral symmetryGO:00098552040.130
striated muscle cell differentiationGO:00511461290.130
nucleobase containing compound biosynthetic processGO:00346542050.129
larval developmentGO:000216420.128
aromatic compound biosynthetic processGO:00194382170.126
regulation of nucleobase containing compound metabolic processGO:00192192500.125
cellular component movementGO:00069283350.124
cellular aromatic compound metabolic processGO:00067252950.122
cell part morphogenesisGO:00329902460.121
regulation of rna biosynthetic processGO:20011412130.115
nucleic acid metabolic processGO:00903042440.114
sensory organ developmentGO:00074233930.112
organic cyclic compound biosynthetic processGO:19013622230.111
cellular macromolecule metabolic processGO:00442603910.106
gene expressionGO:00104672520.101
regulation of signal transductionGO:00099662250.099
negative regulation of cellular processGO:00485232830.098
head developmentGO:00603223030.096
regionalizationGO:00030022740.096
cell substrate adhesionGO:003158940.095
cellular nitrogen compound metabolic processGO:00346412900.095
biosynthetic processGO:00090582940.094
cell morphogenesisGO:00009022890.094
signal transductionGO:00071654550.094
vasculature developmentGO:00019442780.091
cellular biosynthetic processGO:00442492860.088
regulation of biosynthetic processGO:00098892500.088
regulation of cellular metabolic processGO:00313233200.088
macromolecule biosynthetic processGO:00090592270.084
transcription from rna polymerase ii promoterGO:0006366800.084
brain developmentGO:00074202930.083
nitrogen compound metabolic processGO:00068073190.083
regulation of nitrogen compound metabolic processGO:00511712510.083
digestive tract developmentGO:00485652650.083
digestive tract morphogenesisGO:00485462310.082
positive regulation of cellular processGO:00485222010.082
heterocycle biosynthetic processGO:00181302150.081
embryo development ending in birth or egg hatchingGO:00097922710.077
cell projection morphogenesisGO:00488582440.077
regulation of multicellular organism growthGO:004001440.076
cellular macromolecule biosynthetic processGO:00346452240.076
transcription dna templatedGO:00063511810.074
blood vessel developmentGO:00015682460.073
positive regulation of transportGO:005105020.072
regulation of primary metabolic processGO:00800903110.072
stem cell maintenanceGO:001982740.070
regulation of rna metabolic processGO:00512522240.069
determination of heart left right asymmetryGO:00613711170.069
rna metabolic processGO:00160702190.069
central nervous system developmentGO:00074173870.067
heart developmentGO:00075073130.067
regulation of transcription dna templatedGO:00063552130.064
cellular nitrogen compound biosynthetic processGO:00442712180.064
regulation of biological qualityGO:00650082630.063
striated muscle tissue developmentGO:00147061100.061
locomotionGO:00400113130.060
blood vessel morphogenesisGO:00485142160.060
regulation of macromolecule biosynthetic processGO:00105562250.059
regulation of multicellular organismal developmentGO:20000262230.059
neuron differentiationGO:00301823530.057
muscle cell developmentGO:00550011150.056
cell projection organizationGO:00300302840.055
nucleocytoplasmic transportGO:000691340.055
tube morphogenesisGO:00352393490.055
gastrulationGO:00073692080.055
multicellular organism growthGO:003526440.053
skeletal system developmentGO:00015011810.053
neuron developmentGO:00486662620.053
regulation of cytokine productionGO:000181730.053
growthGO:00400071740.052
organic substance biosynthetic processGO:19015762890.052
regulation of metabolic processGO:00192223590.051
germ line stem cell maintenanceGO:003071820.051
rna biosynthetic processGO:00327741810.050
eye developmentGO:00016542770.050
negative regulation of cell communicationGO:0010648960.049
regulation of signalingGO:00230512350.049
skeletal muscle tissue developmentGO:0007519670.048
immune system developmentGO:00025201910.048
establishment of protein localization to organelleGO:007259440.047
inner ear developmentGO:00488391260.047
nucleic acid templated transcriptionGO:00976591810.047
phagocytosisGO:000690930.045
sensory organ morphogenesisGO:00905962000.045
anterior posterior pattern specificationGO:00099521520.045
deathGO:00162651210.045
forebrain developmentGO:0030900960.045
negative regulation of signalingGO:0023057960.044
notochord developmentGO:0030903540.044
regulation of bindingGO:005109830.043
determination of left right symmetryGO:00073681790.043
regulation of macromolecule metabolic processGO:00602553170.042
renal system developmentGO:0072001940.042
neuron projection developmentGO:00311751800.042
nuclear transportGO:005116940.042
regulation of nucleic acid templated transcriptionGO:19035062130.041
neuron projection morphogenesisGO:00488121610.041
protein import into nucleusGO:000660630.041
gland developmentGO:00487321430.039
regulation of transcription from rna polymerase ii promoterGO:00063571140.039
regulation of establishment of protein localizationGO:007020140.039
cell migrationGO:00164772370.039
heart loopingGO:0001947940.039
negative regulation of response to stimulusGO:00485851040.039
regulation of protein targetingGO:190353320.039
cellular component assemblyGO:00226071700.038
regulation of localizationGO:00328791040.038
regulation of cellular macromolecule biosynthetic processGO:20001122220.038
regulation of protein import into nucleusGO:004230620.037
regulation of developmental processGO:00507932470.037
skeletal muscle organ developmentGO:0060538780.037
protein targeting to nucleusGO:004474430.037
protein localization to nucleusGO:003450430.036
heart morphogenesisGO:00030071560.036
response to stressGO:00069502630.036
lipid storageGO:001991510.035
regulation of cellular biosynthetic processGO:00313262450.035
regulation of cell differentiationGO:00455951420.035
camera type eye developmentGO:00430102220.035
meiotic nuclear divisionGO:000712640.035
muscle cell differentiationGO:00426921390.035
embryonic skeletal system morphogenesisGO:0048704930.034
establishment of localizationGO:00512342440.034
epithelial cell differentiationGO:00308551160.034
enzyme linked receptor protein signaling pathwayGO:00071671060.034
generation of neuronsGO:00486993850.033
neurological system processGO:0050877620.033
apoptotic processGO:00069151160.033
transportGO:00068102200.033
specification of symmetryGO:00097992040.033
cell motilityGO:00488702440.032
single organism nuclear importGO:190259330.032
morphogenesis of an epitheliumGO:00020093330.032
axon developmentGO:00615641660.032
oocyte maturationGO:000155640.032
heart joggingGO:0003146400.032
localization of cellGO:00516742440.031
immune system processGO:00023762410.031
programmed cell deathGO:00125011190.031
hemopoiesisGO:00300971830.031
agingGO:000756820.031
embryonic hemopoiesisGO:0035162530.030
positive regulation of cell adhesionGO:004578510.030
single organism transportGO:00447652060.030
negative regulation of muscle cell differentiationGO:005114810.030
regulation of epithelial cell proliferationGO:005067830.030
regulation of intracellular protein transportGO:003315730.029
positive regulation of cellular component biogenesisGO:004408930.029
muscle organ developmentGO:00075171010.029
regulation of protein localization to nucleusGO:190018020.028
regulation of protein transportGO:005122330.028
negative regulation of signal transductionGO:0009968940.028
skeletal system morphogenesisGO:00487051020.028
response to woundingGO:00096111160.028
ear developmentGO:00435831270.028
stem cell divisionGO:001714510.028
embryonic heart tube morphogenesisGO:00031431080.027
positive regulation of cell cycleGO:004578730.027
regulation of cellular component organizationGO:0051128860.027
cardiac atrium morphogenesisGO:000320920.027
cell morphogenesis involved in neuron differentiationGO:00486671630.027
axon guidanceGO:0007411860.027
adult behaviorGO:003053420.027
wound healingGO:0042060900.026
rhombomere morphogenesisGO:0021593170.026
compound eye developmentGO:004874920.026
positive regulation of cytokine productionGO:000181920.025
angiogenesisGO:00015251580.025
nuclear importGO:005117030.025
regulation of reproductive processGO:200024140.025
b cell activationGO:004211320.025
phagocytosis engulfmentGO:000691110.024
skeletal muscle fiber developmentGO:0048741350.024
axonogenesisGO:00074091520.024
cellular response to extracellular stimulusGO:003166820.024
cell migration involved in gastrulationGO:0042074790.024
regulation of cell activationGO:005086510.024
organelle organizationGO:00069962270.024
convergent extensionGO:00600261180.023
regulation of oocyte developmentGO:006028130.023
cardiac muscle tissue developmentGO:0048738480.023
developmental growthGO:00485891660.023
cellular response to nutrient levelsGO:003166920.023
single organism metabolic processGO:00447102170.023
cell matrix adhesionGO:000716040.023
protein importGO:001703830.023
mesenchymal cell developmentGO:0014031780.022
cilium morphogenesisGO:0060271850.022
cardiac atrium developmentGO:000323040.022
eye morphogenesisGO:00485921440.022
urogenital system developmentGO:0001655970.022
positive regulation of cytosolic calcium ion concentrationGO:000720440.022
chordate embryonic developmentGO:00430092710.022
maintenance of locationGO:005123540.022
cell deathGO:00082191210.022
somatic muscle developmentGO:000752540.021
hematopoietic or lymphoid organ developmentGO:00485341910.021
positive regulation of cell substrate adhesionGO:001081110.021
single organism localizationGO:19025782250.021
regulation of i kappab kinase nf kappab signalingGO:004312240.021
dorsal ventral pattern formationGO:00099531250.020
response to corticosteroidGO:003196010.020
regulation of embryonic developmentGO:0045995470.020
positive regulation of metabolic processGO:00098931080.020
cell projection assemblyGO:0030031640.020
camera type eye morphogenesisGO:00485931080.020
muscle fiber developmentGO:0048747520.020
striated muscle cell developmentGO:00550021080.020
regulation of protein bindingGO:004339330.020
regulation of cell deathGO:00109411030.020
protein metabolic processGO:00195381830.020
glial cell differentiationGO:0010001420.019
positive regulation of nitrogen compound metabolic processGO:0051173690.019
mitotic dna damage checkpointGO:004477340.019
cellular response to lipopolysaccharideGO:007122230.019
determination of dorsal ventral asymmetryGO:0048262340.019
retina development in camera type eyeGO:00600411460.019
regulation of nucleocytoplasmic transportGO:004682220.019
bmp signaling pathway involved in determination of left right symmetryGO:0003154140.019
g1 s transition of mitotic cell cycleGO:000008210.019
meiotic cell cycle processGO:190304630.018
cellular component biogenesisGO:00440851780.018
transmission of nerve impulseGO:0019226190.018
female gonad developmentGO:000858540.018
regulation of protein ubiquitinationGO:003139630.018
cell cycle g1 s phase transitionGO:004484310.018
positive regulation of cellular metabolic processGO:0031325940.018
spermatid developmentGO:000728620.018
mesenchyme developmentGO:00604851270.018
regulation of synapse organizationGO:005080730.018
kidney developmentGO:0001822920.018
regulation of cytoplasmic transportGO:190364940.018
regulation of meiotic cell cycleGO:005144510.018
response to organic substanceGO:00100331530.017
cellular component disassemblyGO:002241110.017
response to glucoseGO:000974930.017
embryonic skeletal system developmentGO:0048706970.017
response to carbohydrateGO:000974330.017
secondary metabolic processGO:001974830.017
embryonic cranial skeleton morphogenesisGO:0048701900.017
regulation of cytokine biosynthetic processGO:004203510.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.017
positive regulation of epithelial cell differentiationGO:003085820.017
cellular response to endogenous stimulusGO:0071495680.017
cellular response to external stimulusGO:007149620.017
response to fluid shear stressGO:003440520.017
cellular protein metabolic processGO:00442671290.017
response to chemicalGO:00422213200.017
skin developmentGO:0043588540.017
mononuclear cell proliferationGO:003294310.017
ameboidal type cell migrationGO:00016671430.017
adherens junction organizationGO:003433240.017
notch signaling pathwayGO:0007219350.017
myotube differentiationGO:0014902450.017
carboxylic acid metabolic processGO:0019752220.017
embryonic heart tube developmentGO:00350501330.017
cell proliferation involved in heart morphogenesisGO:006132320.016
positive regulation of multicellular organismal processGO:0051240520.016
regulation of cellular amine metabolic processGO:003323800.016
ubiquitin dependent protein catabolic processGO:000651130.016
positive regulation of macromolecule biosynthetic processGO:0010557590.016
single organism organelle organizationGO:19025891990.016
negative regulation of protein phosphorylationGO:000193340.016
cellular protein catabolic processGO:004425740.016
fin developmentGO:0033333770.016
circulatory system processGO:0003013870.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.016
cell proliferationGO:0008283800.016
positive regulation of cell activationGO:005086710.016
positive regulation of response to stimulusGO:0048584800.016
determination of ventral identityGO:0048264210.016
tissue regenerationGO:0042246740.016
regulation of protein modification by small protein conjugation or removalGO:190332030.016
positive regulation of dna metabolic processGO:005105410.016
peptidyl lysine acetylationGO:001839420.016
cellular response to biotic stimulusGO:007121630.016
cell adhesion mediated by integrinGO:003362710.016
bmp signaling pathwayGO:0030509520.015
spermatid differentiationGO:004851520.015
negative regulation of cytokine productionGO:000181810.015
guanosine containing compound metabolic processGO:190106840.015
response to other organismGO:0051707970.015
nerve developmentGO:0021675450.015
neuronal action potentialGO:0019228180.015
stem cell differentiationGO:00488631170.015
b cell differentiationGO:003018310.015
hepaticobiliary system developmentGO:0061008980.015
olfactory bulb developmentGO:002177240.015
negative regulation of striated muscle tissue developmentGO:004584320.015
regulation of gtp catabolic processGO:003312420.015
cartilage developmentGO:0051216960.015
positive regulation of transcription dna templatedGO:0045893570.015
multicellular organismal macromolecule metabolic processGO:004425920.015
lymphocyte proliferationGO:004665110.015
response to external stimulusGO:00096052640.015
regulation of cell proliferationGO:0042127370.015
retina morphogenesis in camera type eyeGO:0060042790.015
protein homooligomerizationGO:005126030.014
olfactory lobe developmentGO:002198840.014
neural crest cell differentiationGO:0014033720.014
pronephros developmentGO:0048793690.014
phosphate containing compound metabolic processGO:00067961080.014
regulation of mesenchymal cell proliferationGO:001046410.014
regulation of skeletal muscle tissue developmentGO:004864140.014
epithelial tube morphogenesisGO:00605621480.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.014
somite developmentGO:0061053960.014
cellular process involved in reproduction in multicellular organismGO:0022412280.014
collagen metabolic processGO:003296320.014
intracellular signal transductionGO:0035556850.014
formation of primary germ layerGO:0001704620.014
regulation of nucleoside metabolic processGO:000911820.014
embryonic digestive tract developmentGO:004856640.014
dna templated transcription elongationGO:000635430.014
membrane invaginationGO:001032410.014
multi organism processGO:00517041340.014
reactive oxygen species biosynthetic processGO:190340910.014
negative regulation of nucleobase containing compound metabolic processGO:0045934590.014
regulation of cell motilityGO:2000145460.014
response to hexoseGO:000974630.014
cellular response to organic substanceGO:00713101050.013
connective tissue developmentGO:0061448990.013
kupffer s vesicle developmentGO:0070121500.013
gtp catabolic processGO:000618420.013
protein acetylationGO:000647320.013
mitotic dna integrity checkpointGO:004477440.013
system processGO:00030081850.013
negative regulation of gene expressionGO:0010629650.013
embryonic viscerocranium morphogenesisGO:0048703520.013
negative regulation of nitrogen compound metabolic processGO:0051172590.013
cellular response to molecule of bacterial originGO:007121930.013
liver developmentGO:0001889960.013
outflow tract morphogenesisGO:000315110.013
embryonic eye morphogenesisGO:0048048300.013
phosphorus metabolic processGO:00067931090.013
organonitrogen compound metabolic processGO:1901564740.013
stem cell proliferationGO:007208940.013
neuron projection guidanceGO:0097485860.013
proteasomal protein catabolic processGO:001049820.013
single organism cellular localizationGO:1902580460.013
negative regulation of metabolic processGO:0009892860.013
regulation of bmp signaling pathwayGO:0030510390.013
negative regulation of apoptotic processGO:0043066550.013
lateral inhibitionGO:004633110.012
cellular amine metabolic processGO:004410620.012
regulation of apoptotic processGO:0042981980.012
meiotic chromosome segregationGO:004513230.012
sensory perception of chemical stimulusGO:000760630.012
cell cycle arrestGO:000705010.012
fatty acid biosynthetic processGO:000663340.012
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.012
embryonic skeletal joint developmentGO:007249830.012
internal peptidyl lysine acetylationGO:001839320.012
negative regulation of cellular metabolic processGO:0031324770.012
negative regulation of reproductive processGO:200024230.012
positive regulation of macromolecule metabolic processGO:0010604930.012
positive regulation of rna biosynthetic processGO:1902680570.012
regulation of skeletal muscle fiber developmentGO:004874220.012
heart processGO:0003015710.012
regulation of organelle assemblyGO:190211540.012
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetryGO:1900094170.012
photoreceptor cell fate commitmentGO:004655210.012
homeostatic processGO:00425921420.012
rhombomere formationGO:0021594120.012
multicellular organismal metabolic processGO:004423620.012
neural crest cell migrationGO:0001755420.012
i kappab kinase nf kappab signalingGO:000724940.012
female sex differentiationGO:004666040.012
cellular response to starvationGO:000926710.012
cognitionGO:005089010.012
negative regulation of macromolecule metabolic processGO:0010605760.012
anatomical structure arrangementGO:004853220.012
modification dependent macromolecule catabolic processGO:004363230.012
cell substrate junction assemblyGO:000704420.012
proteolysis involved in cellular protein catabolic processGO:005160330.012
regulation of cell adhesionGO:0030155150.012
regulation of locomotionGO:0040012550.012
chemosensory behaviorGO:000763510.012
convergent extension involved in gastrulationGO:0060027710.012
regulation of reactive oxygen species metabolic processGO:200037720.012
blood circulationGO:0008015870.011
regulation of bone mineralizationGO:003050020.011
negative regulation of dna metabolic processGO:005105340.011
response to monosaccharideGO:003428430.011
macromolecular complex subunit organizationGO:0043933740.011
ribonucleoside monophosphate catabolic processGO:000915840.011
modification dependent protein catabolic processGO:001994130.011
ventricular cardiac muscle tissue morphogenesisGO:005501020.011
ventricular cardiac muscle tissue developmentGO:000322930.011
actin polymerization or depolymerizationGO:000815420.011
establishment of localization in cellGO:0051649770.011
cellular protein modification processGO:00064641000.011
mesendoderm developmentGO:0048382100.011
organic substance transportGO:0071702580.011
cardiac chamber developmentGO:0003205190.011
cellular component assembly involved in morphogenesisGO:00109271070.011
positive regulation of muscle cell differentiationGO:005114910.011
protein acylationGO:004354330.011
neuron recognitionGO:0008038180.011
cell fate commitmentGO:0045165990.011
regulation of cell developmentGO:00602841000.011
regulation of alternative mrna splicing via spliceosomeGO:000038110.011
cell adhesionGO:0007155400.011
mesoderm developmentGO:0007498880.011
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.011
type b pancreatic cell developmentGO:000332340.011
positive regulation of developmental processGO:0051094500.011
regulation of synapse assemblyGO:005196330.011
regulation of transcription from rna polymerase ii promoter involved in heart developmentGO:1901213150.011
cell surface receptor signaling pathway involved in heart developmentGO:0061311200.011
mesenchymal cell differentiationGO:0048762870.011
hindbrain developmentGO:0030902910.011
lipid homeostasisGO:005508830.011
regulation of cell proliferation involved in heart morphogenesisGO:200013620.011
septum transversum developmentGO:000334340.011
amine metabolic processGO:000930820.011
positive regulation of signal transductionGO:0009967560.011
endoderm formationGO:0001706290.011
negative regulation of cell deathGO:0060548600.011
production of molecular mediator of immune responseGO:000244020.011
positive regulation of secretion by cellGO:190353210.011
somitogenesisGO:0001756870.011
leukocyte proliferationGO:007066110.011
chemotaxisGO:00069351040.011
endoderm developmentGO:0007492490.011
rhombomere developmentGO:0021546190.011
hard palate developmentGO:006002240.011
endocrine system developmentGO:0035270650.011
epibolyGO:0090504410.011
regulation of organ growthGO:004662030.011
multicellular organismal signalingGO:0035637220.010
canonical wnt signaling pathwayGO:0060070480.010
phosphorylationGO:0016310690.010
regulation of cellular component movementGO:0051270550.010
regulation of cellular amino acid metabolic processGO:000652100.010
proepicardium developmentGO:000334240.010
cardiac chamber formationGO:000320740.010
rho protein signal transductionGO:000726650.010
regulation of purine nucleotide catabolic processGO:003312120.010
establishment of protein localization to plasma membraneGO:009000210.010
regulation of system processGO:0044057400.010
regulation of transporter activityGO:003240920.010
response to oxygen containing compoundGO:1901700550.010
regulation of cell projection assemblyGO:006049140.010
positive regulation of map kinase activityGO:004340630.010
positive regulation of biosynthetic processGO:0009891680.010
single organism intracellular transportGO:1902582250.010
polarized epithelial cell differentiationGO:003085940.010
transmembrane transportGO:00550851200.010
positive regulation of cytoskeleton organizationGO:005149530.010
heart valve formationGO:000318840.010

apln disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.040
nervous system diseaseDOID:86300.023
sensory system diseaseDOID:005015500.018
eye and adnexa diseaseDOID:149200.018
cancerDOID:16200.018
disease of cellular proliferationDOID:1456600.018
musculoskeletal system diseaseDOID:1700.014
eye diseaseDOID:561400.012
organ system cancerDOID:005068600.010