Danio rerio

0 known processes

npc2

Niemann-Pick disease, type C2

(Aliases: sb:cb292,cb292)

npc2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.290
autophagyGO:000691440.172
developmental growthGO:00485891660.168
protein stabilizationGO:005082120.135
cellular protein catabolic processGO:004425740.135
cell surface receptor signaling pathwayGO:00071663250.108
embryo development ending in birth or egg hatchingGO:00097922710.101
regulation of metabolic processGO:00192223590.087
programmed cell deathGO:00125011190.087
regulation of cell deathGO:00109411030.086
regulation of gene expressionGO:00104682650.081
regulation of blood pressureGO:000821710.080
endosomal transportGO:001619720.079
deathGO:00162651210.075
immune system processGO:00023762410.070
multicellular organismal macromolecule metabolic processGO:004425920.069
response to hexoseGO:000974630.065
response to glucoseGO:000974930.065
response to stressGO:00069502630.061
positive regulation of transportGO:005105020.059
cellular response to starvationGO:000926710.059
glial cell migrationGO:000834730.059
morphogenesis of an epitheliumGO:00020093330.058
gene expressionGO:00104672520.056
adult behaviorGO:003053420.054
negative regulation of biological processGO:00485193040.053
cell deathGO:00082191210.053
collagen metabolic processGO:003296320.050
establishment of localizationGO:00512342440.049
organic substance biosynthetic processGO:19015762890.048
agingGO:000756820.047
regulation of synapse assemblyGO:005196330.047
response to external stimulusGO:00096052640.047
regulation of cell communicationGO:00106462320.046
regulation of proteolysisGO:0030162240.045
regulation of peptidase activityGO:0052547230.044
multicellular organism growthGO:003526440.043
cellular response to extracellular stimulusGO:003166820.043
tube morphogenesisGO:00352393490.042
embryonic cranial skeleton morphogenesisGO:0048701900.041
response to carbohydrateGO:000974330.041
regulation of biological qualityGO:00650082630.040
response to monosaccharideGO:003428430.039
embryonic skeletal system morphogenesisGO:0048704930.038
cellular macromolecule metabolic processGO:00442603910.038
biosynthetic processGO:00090582940.036
proteolysisGO:0006508380.036
lipid storageGO:001991510.036
protein targeting to nucleusGO:004474430.036
establishment of protein localization to organelleGO:007259440.036
regulation of blood vessel sizeGO:005088020.036
cellular biosynthetic processGO:00442492860.034
response to corticosteroidGO:003196010.034
synaptic vesicle endocytosisGO:004848810.034
locomotionGO:00400113130.033
proteolysis involved in cellular protein catabolic processGO:005160330.033
lytic vacuole organizationGO:008017110.033
blood vessel developmentGO:00015682460.032
negative regulation of catabolic processGO:000989530.032
hormone transportGO:000991420.032
negative regulation of cellular processGO:00485232830.032
growthGO:00400071740.032
synaptic growth at neuromuscular junctionGO:005112420.031
sensory organ developmentGO:00074233930.031
regulation of synapse organizationGO:005080730.030
regulation of signal transductionGO:00099662250.029
synaptic vesicle recyclingGO:003646510.029
response to organic substanceGO:00100331530.028
protein localization to nucleusGO:003450430.028
regulation of apoptotic processGO:0042981980.028
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.028
regulation of multicellular organism growthGO:004001440.028
maintenance of locationGO:005123540.027
modification dependent protein catabolic processGO:001994130.027
regulation of multicellular organismal processGO:00512392770.027
regulation of developmental processGO:00507932470.026
organic substance transportGO:0071702580.026
response to glucocorticoidGO:005138410.026
multi organism processGO:00517041340.025
organonitrogen compound metabolic processGO:1901564740.025
organelle fusionGO:004828430.025
embryonic viscerocranium morphogenesisGO:0048703520.025
gtp catabolic processGO:000618420.025
cellular response to organic substanceGO:00713101050.024
cellular response to nutrient levelsGO:003166920.024
regulation of endopeptidase activityGO:0052548230.024
positive regulation of cellular catabolic processGO:003133130.023
cellular component assemblyGO:00226071700.023
nuclear transportGO:005116940.023
single organism transportGO:00447652060.023
positive regulation of apoptotic signaling pathwayGO:200123510.023
regulation of cellular metabolic processGO:00313233200.023
positive regulation of biological processGO:00485182530.023
signal transductionGO:00071654550.022
protein import into nucleusGO:000660630.022
apoptotic processGO:00069151160.022
regulation of cellular response to oxidative stressGO:190040720.022
organic cyclic compound biosynthetic processGO:19013622230.021
organic cyclic compound metabolic processGO:19013603010.021
hormone secretionGO:004687920.021
regulation of hormone secretionGO:004688320.021
blood vessel morphogenesisGO:00485142160.021
nucleic acid transportGO:005065720.020
nitrogen compound metabolic processGO:00068073190.020
regulation of multicellular organismal developmentGO:20000262230.020
regulation of rna metabolic processGO:00512522240.020
single organism nuclear importGO:190259330.020
cellular ketone metabolic processGO:0042180110.020
central nervous system developmentGO:00074173870.020
response to chemicalGO:00422213200.020
small molecule metabolic processGO:0044281770.019
cellular response to chemical stimulusGO:00708871570.019
regulation of cellular protein catabolic processGO:190336210.019
guanosine containing compound catabolic processGO:190106920.019
regulation of response to stimulusGO:00485832690.019
cellular protein metabolic processGO:00442671290.019
cellular response to unfolded proteinGO:003462020.019
er nucleus signaling pathwayGO:000698420.018
stem cell divisionGO:001714510.018
rna metabolic processGO:00160702190.018
positive regulation of cellular amine metabolic processGO:003324000.018
regulation of cell activationGO:005086510.018
guanosine containing compound metabolic processGO:190106840.018
response to topologically incorrect proteinGO:003596620.018
g protein coupled receptor signaling pathwayGO:0007186740.018
single organism metabolic processGO:00447102170.018
response to steroid hormoneGO:0048545350.018
multicellular organismal metabolic processGO:004423620.018
single organism localizationGO:19025782250.018
protein metabolic processGO:00195381830.017
glucose homeostasisGO:004259310.017
response to amineGO:001407510.017
regulation of protein catabolic processGO:004217610.017
phagocytosisGO:000690930.017
protein importGO:001703830.017
chordate embryonic developmentGO:00430092710.017
positive regulation of secretion by cellGO:190353210.017
macroautophagyGO:001623610.017
macromolecule biosynthetic processGO:00090592270.017
nucleocytoplasmic transportGO:000691340.016
embryonic skeletal system developmentGO:0048706970.016
cellular aldehyde metabolic processGO:000608140.016
positive regulation of blood circulationGO:190352420.016
regulation of cytokine productionGO:000181730.016
negative regulation of cell deathGO:0060548600.016
hormone biosynthetic processGO:004244630.016
gtp metabolic processGO:004603940.016
regulation of macromolecule metabolic processGO:00602553170.016
regulation of tube sizeGO:003515020.016
single organism biosynthetic processGO:0044711710.016
ubiquitin dependent protein catabolic processGO:000651130.016
muscle organ developmentGO:00075171010.016
positive regulation of catabolic processGO:000989640.016
regulation of protein targetingGO:190353320.016
negative regulation of autophagyGO:001050710.015
cellular response to reactive oxygen speciesGO:003461420.015
positive regulation of multicellular organismal processGO:0051240520.015
rna biosynthetic processGO:00327741810.015
regulation of protein transportGO:005122330.015
negative regulation of cellular catabolic processGO:003133030.015
tissue regenerationGO:0042246740.015
interspecies interaction between organismsGO:004441940.015
skeletal system morphogenesisGO:00487051020.015
response to hormoneGO:0009725480.015
stem cell proliferationGO:007208940.015
immune system developmentGO:00025201910.014
cell death in response to oxidative stressGO:003647320.014
positive regulation of cellular processGO:00485222010.014
rna localizationGO:000640340.014
lysosomal transportGO:000704120.014
negative regulation of epithelial cell proliferationGO:005068010.014
cellular component movementGO:00069283350.014
regulation of phGO:000688530.014
cellular response to external stimulusGO:007149620.014
cellular amine metabolic processGO:004410620.014
stem cell maintenanceGO:001982740.014
skeletal system developmentGO:00015011810.014
nuclear importGO:005117030.014
regulation of protein import into nucleusGO:004230620.014
vasculature developmentGO:00019442780.014
regulation of primary metabolic processGO:00800903110.014
synaptic vesicle transportGO:004848910.014
regenerationGO:0031099910.014
extrinsic apoptotic signaling pathwayGO:009719130.014
negative regulation of cell communicationGO:0010648960.013
membrane fusionGO:006102520.013
epithelial cell differentiationGO:00308551160.013
regulation of inflammatory responseGO:005072720.013
angiogenesisGO:00015251580.013
striated muscle tissue developmentGO:00147061100.013
single organism organelle organizationGO:19025891990.013
cell migration involved in heart developmentGO:0060973220.013
protein targeting to membraneGO:000661210.013
regulation of cellular component organizationGO:0051128860.013
response to ketoneGO:190165410.013
regulation of epithelial cell proliferationGO:005067830.013
calcium mediated signalingGO:001972220.013
regulation of autophagyGO:001050630.013
defense response to bacteriumGO:0042742220.013
axon ensheathment in central nervous systemGO:003229120.013
positive regulation of secretionGO:005104710.013
muscle structure developmentGO:00610611960.013
regulation of cellular ketone metabolic processGO:001056570.013
regulation of signalingGO:00230512350.013
amine metabolic processGO:000930820.013
cellular response to molecule of bacterial originGO:007121930.013
nitric oxide metabolic processGO:004620920.013
regulation of cytoplasmic transportGO:190364940.013
cellular response to hormone stimulusGO:0032870390.013
lipoprotein metabolic processGO:004215740.013
mitochondrion organizationGO:000700540.013
regulation of macromolecule biosynthetic processGO:00105562250.013
endosome to lysosome transportGO:000833310.013
negative regulation of protein transportGO:005122430.012
lipid biosynthetic processGO:0008610220.012
peptide transportGO:001583310.012
establishment of organelle localizationGO:0051656450.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
cellular amino acid metabolic processGO:000652070.012
urogenital system developmentGO:0001655970.012
meiotic nuclear divisionGO:000712640.012
regulation of organ growthGO:004662030.012
response to woundingGO:00096111160.012
nucleobase containing compound metabolic processGO:00061392740.012
compound eye developmentGO:004874920.012
regulation of nucleotide catabolic processGO:003081120.012
positive regulation of cellular metabolic processGO:0031325940.012
regulation of nervous system developmentGO:0051960900.012
regulation of cellular amine metabolic processGO:003323800.012
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.012
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.012
regulation of oligodendrocyte differentiationGO:004871310.012
antimicrobial humoral responseGO:001973020.012
cellular response to steroid hormone stimulusGO:0071383310.012
regulation of extrinsic apoptotic signaling pathwayGO:200123630.012
establishment of localization in cellGO:0051649770.012
regulation of cell differentiationGO:00455951420.012
behaviorGO:0007610740.012
nucleobase containing compound transportGO:001593120.012
establishment of rna localizationGO:005123630.012
connective tissue developmentGO:0061448990.012
head developmentGO:00603223030.012
multi organism cellular processGO:004476420.012
organelle localizationGO:0051640490.012
morphogenesis of a branching epitheliumGO:0061138160.012
neuroblast proliferationGO:000740520.012
rna transportGO:005065820.012
tissue remodelingGO:004877140.012
negative regulation of signalingGO:0023057960.012
positive regulation of apoptotic processGO:0043065290.011
regulation of bindingGO:005109830.011
negative regulation of cytoplasmic transportGO:190365020.011
regulation of nucleocytoplasmic transportGO:004682220.011
organic acid metabolic processGO:0006082310.011
regulation of cell shapeGO:000836010.011
endoplasmic reticulum unfolded protein responseGO:003096820.011
protein polyubiquitinationGO:000020940.011
positive regulation of cellular component biogenesisGO:004408930.011
protein acylationGO:004354330.011
epithelial tube morphogenesisGO:00605621480.011
regulation of cellular amino acid metabolic processGO:000652100.011
enzyme linked receptor protein signaling pathwayGO:00071671060.011
response to bacteriumGO:0009617580.011
cellular response to biotic stimulusGO:007121630.011
interaction with hostGO:005170140.011
regulation of gtpase activityGO:004308720.011
cellular response to estrogen stimulusGO:0071391240.011
regulation of nucleoside metabolic processGO:000911820.011
regulation of programmed cell deathGO:00430671010.011
establishment of synaptic vesicle localizationGO:009748010.011
multicellular organismal response to stressGO:003355520.011
sensory perception of chemical stimulusGO:000760630.011
regulation of protein localization to nucleusGO:190018020.011
peptidyl serine modificationGO:001820920.011
cellular amino acid biosynthetic processGO:000865220.011
innate immune responseGO:0045087130.011
regulation of stem cell differentiationGO:200073640.011
bone remodelingGO:004684920.010
regulation of reproductive processGO:200024140.010
nuclear exportGO:005116810.010
regulation of purine nucleotide catabolic processGO:003312120.010
transportGO:00068102200.010
brain developmentGO:00074202930.010
axonogenesisGO:00074091520.010
golgi vesicle transportGO:004819330.010
wound healingGO:0042060900.010
negative chemotaxisGO:005091910.010
neuron differentiationGO:00301823530.010
vacuole organizationGO:000703390.010
hemopoiesisGO:00300971830.010
regionalizationGO:00030022740.010

npc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.217
nervous system diseaseDOID:86300.067
inherited metabolic disorderDOID:65500.047
disease of metabolismDOID:001466700.047
central nervous system diseaseDOID:33100.020
brain diseaseDOID:93600.020
lysosomal storage diseaseDOID:321100.011