Danio rerio

55 known processes

kdm1a

lysine (K)-specific demethylase 1a

(Aliases: wu:fb82e06,wu:fj36a05,aof2,kdm1,KIAA0601,wu:fj66b06,wu:fc51a02)

kdm1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.533
regulation of meiotic cell cycleGO:005144510.364
regulation of rna metabolic processGO:00512522240.248
cellular macromolecule metabolic processGO:00442603910.229
regulation of nitrogen compound metabolic processGO:00511712510.227
single organism organelle organizationGO:19025891990.215
nucleic acid templated transcriptionGO:00976591810.200
cellular aromatic compound metabolic processGO:00067252950.177
organic cyclic compound metabolic processGO:19013603010.167
regulation of transcription dna templatedGO:00063552130.164
regulation of mrna processingGO:005068430.156
rna metabolic processGO:00160702190.148
regulation of gene expressionGO:00104682650.140
nucleobase containing compound metabolic processGO:00061392740.137
cellular component assemblyGO:00226071700.135
alternative mrna splicing via spliceosomeGO:000038010.128
cellular nitrogen compound metabolic processGO:00346412900.125
heterocycle metabolic processGO:00464832900.121
meiotic nuclear divisionGO:000712640.119
organelle organizationGO:00069962270.118
cellular biosynthetic processGO:00442492860.118
embryo development ending in birth or egg hatchingGO:00097922710.116
regulation of cellular macromolecule biosynthetic processGO:20001122220.116
locomotionGO:00400113130.111
transcription dna templatedGO:00063511810.110
regulation of metabolic processGO:00192223590.109
transportGO:00068102200.107
macromolecule biosynthetic processGO:00090592270.106
regulation of cellular metabolic processGO:00313233200.105
positive regulation of biological processGO:00485182530.100
negative regulation of biological processGO:00485193040.097
regulation of biosynthetic processGO:00098892500.097
gene expressionGO:00104672520.094
neuron developmentGO:00486662620.093
agingGO:000756820.092
positive regulation of catabolic processGO:000989640.087
internal protein amino acid acetylationGO:000647520.084
multi organism processGO:00517041340.084
protein acetylationGO:000647320.084
nitrogen compound metabolic processGO:00068073190.081
cellular component movementGO:00069283350.080
aromatic compound biosynthetic processGO:00194382170.080
nucleic acid metabolic processGO:00903042440.080
organic substance biosynthetic processGO:19015762890.079
internal peptidyl lysine acetylationGO:001839320.078
heterocycle biosynthetic processGO:00181302150.075
negative regulation of rna metabolic processGO:0051253480.075
regulation of macromolecule metabolic processGO:00602553170.075
organic cyclic compound biosynthetic processGO:19013622230.074
cellular nitrogen compound biosynthetic processGO:00442712180.073
rna biosynthetic processGO:00327741810.067
neuron differentiationGO:00301823530.067
negative regulation of cellular processGO:00485232830.067
cellular macromolecule biosynthetic processGO:00346452240.067
positive regulation of cellular processGO:00485222010.065
regulation of primary metabolic processGO:00800903110.064
negative regulation of gene expressionGO:0010629650.064
macromolecular complex subunit organizationGO:0043933740.063
response to stressGO:00069502630.061
signal transductionGO:00071654550.060
positive regulation of nitrogen compound metabolic processGO:0051173690.060
nucleobase containing compound biosynthetic processGO:00346542050.060
regulation of alternative mrna splicing via spliceosomeGO:000038110.059
peptidyl lysine acetylationGO:001839420.059
sensory organ developmentGO:00074233930.058
cell cycleGO:0007049930.058
locomotor rhythmGO:004547530.058
biosynthetic processGO:00090582940.058
positive regulation of myeloid cell differentiationGO:004563920.056
negative regulation of macromolecule metabolic processGO:0010605760.056
sexual reproductionGO:0019953360.052
tube morphogenesisGO:00352393490.050
cell cycle processGO:0022402530.050
rna localizationGO:000640340.050
regulation of macromolecule biosynthetic processGO:00105562250.049
cellular component biogenesisGO:00440851780.049
establishment of localizationGO:00512342440.049
negative regulation of cellular metabolic processGO:0031324770.047
positive regulation of macromolecule biosynthetic processGO:0010557590.047
regulation of cellular carbohydrate metabolic processGO:001067540.046
negative regulation of metabolic processGO:0009892860.046
response to external stimulusGO:00096052640.045
positive regulation of transportGO:005105020.045
protein acylationGO:004354330.044
positive regulation of cellular metabolic processGO:0031325940.044
maintenance of locationGO:005123540.043
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.043
protein demethylationGO:000648220.043
camera type eye developmentGO:00430102220.042
protein metabolic processGO:00195381830.042
regulation of protein complex assemblyGO:004325430.042
rhythmic processGO:0048511210.042
cell migrationGO:00164772370.041
cell surface receptor signaling pathwayGO:00071663250.040
positive regulation of nucleobase containing compound metabolic processGO:0045935690.040
regulation of developmental processGO:00507932470.039
gastrulationGO:00073692080.039
histone lysine demethylationGO:007007620.039
modification dependent protein catabolic processGO:001994130.039
rna transportGO:005065820.038
lipid storageGO:001991510.038
regulation of protein catabolic processGO:004217610.038
adult behaviorGO:003053420.037
positive regulation of cellular catabolic processGO:003133130.037
regulation of biological qualityGO:00650082630.037
regulation of rna biosynthetic processGO:20011412130.036
system processGO:00030081850.036
female gonad developmentGO:000858540.036
purine nucleoside monophosphate catabolic processGO:000912840.036
positive regulation of transcription dna templatedGO:0045893570.036
heart developmentGO:00075073130.035
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.035
cellular protein metabolic processGO:00442671290.035
nucleoside monophosphate catabolic processGO:000912540.035
negative regulation of rna splicingGO:003311910.035
negative regulation of synapse assemblyGO:005196420.035
epithelial cell differentiationGO:00308551160.034
regulation of mrna splicing via spliceosomeGO:004802430.034
nuclear exportGO:005116810.034
regulation of nucleobase containing compound metabolic processGO:00192192500.034
negative regulation of nucleobase containing compound metabolic processGO:0045934590.033
response to biotic stimulusGO:0009607970.033
transcription from rna polymerase ii promoterGO:0006366800.033
nuclear transportGO:005116940.033
nucleic acid transportGO:005065720.033
regulation of reproductive processGO:200024140.032
negative regulation of macromolecule biosynthetic processGO:0010558480.032
regulation of cellular ketone metabolic processGO:001056570.032
cellular component morphogenesisGO:00329893360.031
regulation of cell activationGO:005086510.031
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377100.030
rna export from nucleusGO:000640510.030
regulation of chromosome segregationGO:005198310.030
developmental process involved in reproductionGO:0003006270.030
positive regulation of metabolic processGO:00098931080.030
atp catabolic processGO:000620040.030
growthGO:00400071740.030
response to chemicalGO:00422213200.030
ubiquitin dependent protein catabolic processGO:000651130.030
single organism nuclear importGO:190259330.030
proteasomal protein catabolic processGO:001049820.030
nucleocytoplasmic transportGO:000691340.029
digestive tract developmentGO:00485652650.029
localization of cellGO:00516742440.028
rna processingGO:0006396250.028
apoptotic processGO:00069151160.028
cellular response to extracellular stimulusGO:003166820.028
cellular response to nutrient levelsGO:003166920.028
regulation of synapse assemblyGO:005196330.028
cellular protein modification processGO:00064641000.027
regionalizationGO:00030022740.027
muscle tissue developmentGO:00605371100.027
ribonucleoside monophosphate catabolic processGO:000915840.027
positive regulation of epithelial cell differentiationGO:003085820.027
negative regulation of rna biosynthetic processGO:1902679450.026
programmed cell deathGO:00125011190.026
modification dependent macromolecule catabolic processGO:004363230.026
establishment of rna localizationGO:005123630.026
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.026
digestive system developmentGO:00551232890.026
positive regulation of gene expressionGO:0010628710.025
cell morphogenesisGO:00009022890.025
cell projection organizationGO:00300302840.025
regulation of cytokine productionGO:000181730.025
positive regulation of biosynthetic processGO:0009891680.025
regulation of cell shapeGO:000836010.025
cellular macromolecular complex assemblyGO:0034622240.024
regulation of nucleocytoplasmic transportGO:004682220.024
mrna splicing via spliceosomeGO:0000398100.024
proteolysis involved in cellular protein catabolic processGO:005160330.024
regulation of synapse organizationGO:005080730.024
female sex differentiationGO:004666040.024
centrosome organizationGO:005129710.024
positive regulation of cellular component biogenesisGO:004408930.024
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.024
determination of bilateral symmetryGO:00098552040.023
positive regulation of reproductive processGO:200024320.023
cytokinesisGO:000091030.023
positive regulation of rna metabolic processGO:0051254590.023
axon guidanceGO:0007411860.023
cellular response to external stimulusGO:007149620.023
development of primary female sexual characteristicsGO:004654540.023
response to woundingGO:00096111160.023
cell part morphogenesisGO:00329902460.023
positive regulation of cell cycleGO:004578730.023
reproductive processGO:0022414400.023
regulation of multicellular organismal processGO:00512392770.023
regulation of organelle assemblyGO:190211540.023
regulation of epithelial cell proliferationGO:005067830.023
regulation of nucleic acid templated transcriptionGO:19035062130.022
cellular localizationGO:0051641970.022
cell deathGO:00082191210.022
negative regulation of translationGO:001714810.022
single organism reproductive processGO:0044702400.022
mesoderm developmentGO:0007498880.022
protein complex disassemblyGO:004324110.022
single organism metabolic processGO:00447102170.022
intracellular signal transductionGO:0035556850.022
mrna metabolic processGO:0016071200.022
cellular carbohydrate metabolic processGO:004426240.022
regulation of multicellular organismal developmentGO:20000262230.022
neural crest cell developmentGO:0014032620.022
reproductionGO:0000003400.022
positive regulation of macromolecule metabolic processGO:0010604930.022
positive regulation of dna templated transcription elongationGO:003278610.022
exocytosisGO:000688710.022
positive regulation of rna biosynthetic processGO:1902680570.021
meiotic cell cycle processGO:190304630.021
regulation of transcription from rna polymerase ii promoterGO:00063571140.021
digestive tract morphogenesisGO:00485462310.021
regulation of cell cycle processGO:0010564200.021
histone demethylationGO:001657720.021
negative regulation of biosynthetic processGO:0009890550.021
regulation of dna templated transcription elongationGO:003278430.021
nuclear divisionGO:0000280230.021
regulation of bindingGO:005109830.021
eye developmentGO:00016542770.021
cell motilityGO:00488702440.021
mesenchymal cell differentiationGO:0048762870.021
negative regulation of nucleic acid templated transcriptionGO:1903507450.021
synaptic growth at neuromuscular junctionGO:005112420.021
negative regulation of nucleocytoplasmic transportGO:004682320.021
regulation of stem cell differentiationGO:200073640.020
single organism localizationGO:19025782250.020
neuron projection guidanceGO:0097485860.020
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.020
embryonic organ developmentGO:00485683810.020
embryonic organ morphogenesisGO:00485622740.020
protein dealkylationGO:000821420.020
negative regulation of cellular biosynthetic processGO:0031327550.020
regulation of cytoplasmic transportGO:190364940.020
neuronal stem cell maintenanceGO:009715020.020
negative regulation of transcription dna templatedGO:0045892450.020
regulation of establishment of protein localizationGO:007020140.020
regulation of cellular protein catabolic processGO:190336210.019
cellular component disassemblyGO:002241110.019
muscle cell developmentGO:00550011150.019
sister chromatid cohesionGO:000706220.019
circadian regulation of gene expressionGO:003292280.019
response to lipidGO:0033993600.019
autophagyGO:000691440.019
regulation of cell deathGO:00109411030.019
actin polymerization or depolymerizationGO:000815420.018
mitotic cell cycle processGO:1903047480.018
macromolecule modificationGO:00434121110.018
homeostatic processGO:00425921420.018
retina development in camera type eyeGO:00600411460.018
regulation of programmed cell deathGO:00430671010.018
regulation of cellular amine metabolic processGO:003323800.018
cell projection morphogenesisGO:00488582440.018
germ cell developmentGO:0007281220.018
multicellular organism growthGO:003526440.018
cellular amine metabolic processGO:004410620.018
regulation of signalingGO:00230512350.018
negative regulation of mrna processingGO:005068610.018
regulation of cell communicationGO:00106462320.018
establishment of protein localization to organelleGO:007259440.018
nucleobase containing compound transportGO:001593120.018
embryonic cranial skeleton morphogenesisGO:0048701900.017
regulation of muscle contractionGO:000693730.017
cellular response to starvationGO:000926710.017
purine ribonucleoside monophosphate catabolic processGO:000916940.017
dna templated transcription elongationGO:000635430.017
negative regulation of developmental processGO:0051093650.017
stem cell maintenanceGO:001982740.017
negative regulation of nitrogen compound metabolic processGO:0051172590.017
gland developmentGO:00487321430.017
cellular ketone metabolic processGO:0042180110.017
negative regulation of reproductive processGO:200024230.017
regulation of organelle organizationGO:0033043290.017
cell morphogenesis involved in differentiationGO:00009041950.017
multicellular organismal reproductive processGO:0048609350.017
positive regulation of multi organism processGO:004390230.017
regulation of cellular component organizationGO:0051128860.017
regulation of circadian rhythmGO:004275240.017
cell proliferationGO:0008283800.017
morphogenesis of an epitheliumGO:00020093330.017
phagocytosisGO:000690930.016
regulation of signal transductionGO:00099662250.016
axon developmentGO:00615641660.016
gtp catabolic processGO:000618420.016
regulation of multicellular organism growthGO:004001440.016
positive regulation of cell activationGO:005086710.016
carbohydrate biosynthetic processGO:001605110.016
regulation of peptidyl tyrosine phosphorylationGO:005073010.016
regulation of carbohydrate metabolic processGO:000610940.016
cell substrate adhesionGO:003158940.016
protein modification processGO:00362111000.016
embryonic skeletal system developmentGO:0048706970.016
cellular response to organic substanceGO:00713101050.016
negative regulation of histone modificationGO:003105710.016
regulation of microtubule cytoskeleton organizationGO:007050730.016
taxisGO:00423301090.015
response to organic substanceGO:00100331530.015
regulation of cellular biosynthetic processGO:00313262450.015
macromolecule localizationGO:0033036540.015
regulation of rna splicingGO:004348480.015
chemotaxisGO:00069351040.015
amine metabolic processGO:000930820.015
negative regulation of signal transductionGO:0009968940.015
regulation of synaptic growth at neuromuscular junctionGO:000858210.015
protein depolymerizationGO:005126110.015
heart contractionGO:0060047710.015
cell divisionGO:0051301200.015
regulation of apoptotic processGO:0042981980.015
positive regulation of secretion by cellGO:190353210.015
entrainment of circadian clockGO:000964920.015
negative regulation of cytokine productionGO:000181810.015
tissue remodelingGO:004877140.015
stem cell developmentGO:0048864820.015
positive regulation of cytosolic calcium ion concentrationGO:000720440.015
cell matrix adhesionGO:000716040.015
mrna processingGO:0006397140.014
dorsal ventral pattern formationGO:00099531250.014
developmental growthGO:00485891660.014
organelle fissionGO:0048285230.014
regulation of protein bindingGO:004339330.014
peptide transportGO:001583310.014
regulation of dendrite developmentGO:005077330.014
cognitionGO:005089010.014
specification of symmetryGO:00097992040.014
small molecule metabolic processGO:0044281770.014
macromolecular complex disassemblyGO:003298410.014
camera type eye morphogenesisGO:00485931080.014
regulation of protein transportGO:005122330.014
mitotic cell cycleGO:0000278640.014
response to carbohydrateGO:000974330.014
blood circulationGO:0008015870.014
regulation of erk1 and erk2 cascadeGO:007037240.014
somatic muscle developmentGO:000752540.014
regulation of cytokine mediated signaling pathwayGO:000195930.014
regulation of purine nucleotide catabolic processGO:003312120.014
stem cell differentiationGO:00488631170.014
regulation of mrna metabolic processGO:190331160.014
microtubule based processGO:0007017600.014
regulation of cellular amino acid metabolic processGO:000652100.014
regulation of response to cytokine stimulusGO:006075930.014
transcription elongation from rna polymerase ii promoterGO:000636830.014
positive regulation of notch signaling pathwayGO:004574730.014
regulation of protein polymerizationGO:003227120.014
erk1 and erk2 cascadeGO:007037140.013
cellular protein catabolic processGO:004425740.013
directional locomotionGO:003305810.013
cellular response to biotic stimulusGO:007121630.013
striated muscle cell differentiationGO:00511461290.013
mrna 3 end processingGO:003112420.013
positive regulation of ras protein signal transductionGO:004657910.013
positive regulation of nucleotide catabolic processGO:003081310.013
cardiac cell fate commitmentGO:006091110.013
microtubule cytoskeleton organization involved in mitosisGO:190285010.013
regulation of autophagyGO:001050630.013
regulation of cell cycleGO:0051726520.013
regulation of cell proliferationGO:0042127370.013
generation of neuronsGO:00486993850.013
viral processGO:001603210.013
negative regulation of cell communicationGO:0010648960.013
muscle structure developmentGO:00610611960.013
spindle assemblyGO:005122520.013
ovulation cycle processGO:002260220.013
regulation of translational initiationGO:000644610.013
protein importGO:001703830.013
negative regulation of protein kinase activityGO:000646940.013
microtubule cytoskeleton organizationGO:0000226330.013
negative regulation of programmed cell deathGO:0043069580.013
nuclear importGO:005117030.013
embryonic heart tube developmentGO:00350501330.013
determination of left right symmetryGO:00073681790.013
immune system processGO:00023762410.013
regulation of nucleotide catabolic processGO:003081120.012
neurotransmitter secretionGO:000726920.012
negative regulation of defense responseGO:003134820.012
organism emergence from protective structureGO:007168440.012
anterior posterior pattern specificationGO:00099521520.012
regulation of protein localization to nucleusGO:190018020.012
fertilizationGO:000956630.012
negative regulation of multicellular organismal processGO:0051241690.012
protein complex subunit organizationGO:0071822460.012
positive regulation of cytoskeleton organizationGO:005149530.012
regulation of metal ion transportGO:001095940.012
neural crest cell differentiationGO:0014033720.012
neuroblast differentiationGO:001401610.012
positive regulation of nucleic acid templated transcriptionGO:1903508570.012
response to drugGO:004249330.012
mitotic metaphase plate congressionGO:000708010.012
neural crest formationGO:0014029140.012
spermatid differentiationGO:004851520.012
regulation of protein targetingGO:190353320.012
regulation of carbohydrate biosynthetic processGO:004325510.012
rna splicing via transesterification reactionsGO:0000375100.012
dsrna fragmentationGO:003105010.012
myeloid cell differentiationGO:0030099860.012
negative regulation of cytokine mediated signaling pathwayGO:000196020.012
regulation of cell divisionGO:0051302120.012
rna splicingGO:0008380160.012
cellular response to dsrnaGO:007135910.012
protein polymerizationGO:005125840.011
behaviorGO:0007610740.011
negative regulation of response to stimulusGO:00485851040.011
striated muscle cell developmentGO:00550021080.011
neuron projection developmentGO:00311751800.011
skeletal system morphogenesisGO:00487051020.011
chromatin organizationGO:0006325220.011
negative regulation of map kinase activityGO:004340720.011
establishment of synaptic vesicle localizationGO:009748010.011
histone modificationGO:0016570200.011
negative regulation of mrna metabolic processGO:190331230.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
regulation of nucleoside metabolic processGO:000911820.011
spindle assembly involved in mitosisGO:009030710.011
protein targeting to nucleusGO:004474430.011
regulation of inflammatory responseGO:005072720.011
primary neural tube formationGO:001402010.011
energy reserve metabolic processGO:000611220.011
positive regulation of protein complex assemblyGO:003133420.011
response to monosaccharideGO:003428430.011
gamete generationGO:0007276330.011
hormone transportGO:000991420.011
negative regulation of multi organism processGO:004390130.011
muscle organ developmentGO:00075171010.011
somatic stem cell maintenanceGO:003501910.011
establishment of endothelial barrierGO:006102830.011
regulation of transcription from rna polymerase iii promoterGO:000635910.011
interspecies interaction between organismsGO:004441940.011
embryonic skeletal system morphogenesisGO:0048704930.011
regulation of sodium ion transportGO:000202820.011
covalent chromatin modificationGO:0016569200.011
intracellular mrna localizationGO:000829810.011
negative regulation of chromosome organizationGO:200125110.011
response to uvGO:000941130.011
skeletal muscle organ developmentGO:0060538780.011
negative regulation of intracellular transportGO:003238730.011
protein import into nucleusGO:000660630.011
entrainment of circadian clock by photoperiodGO:004315310.011
regulation of epidermis developmentGO:004568220.010
response to oxygen containing compoundGO:1901700550.010
heart morphogenesisGO:00030071560.010
hormone secretionGO:004687920.010
nitrogen compound transportGO:0071705230.010
striated muscle tissue developmentGO:00147061100.010
embryonic heart tube morphogenesisGO:00031431080.010
positive regulation of carbohydrate metabolic processGO:004591310.010
negative regulation of cell deathGO:0060548600.010
neurotransmitter transportGO:000683620.010
regulation of neural precursor cell proliferationGO:200017730.010
positive regulation of developmental processGO:0051094500.010
cell volume homeostasisGO:000688410.010
carboxylic acid metabolic processGO:0019752220.010
regulation of dendrite morphogenesisGO:004881430.010
multi organism reproductive processGO:0044703360.010
positive regulation of translationGO:004572710.010
cellular response to chemical stimulusGO:00708871570.010
macromolecular complex assemblyGO:0065003350.010
negative regulation of protein phosphorylationGO:000193340.010

kdm1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.057
organ system cancerDOID:005068600.029
disease of cellular proliferationDOID:1456600.029
cancerDOID:16200.029
musculoskeletal system diseaseDOID:1700.025
nervous system diseaseDOID:86300.019
cardiovascular system diseaseDOID:128700.015
muscle tissue diseaseDOID:6600.012
muscular diseaseDOID:008000000.012