Danio rerio

15 known processes

map3k7

mitogen activated protein kinase kinase kinase 7

(Aliases: zgc:110612,si:ch211-225h9.1,MGC110612)

map3k7 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.094
agingGO:000756820.056
multicellular organism growthGO:003526440.046
establishment of protein localization to organelleGO:007259440.041
positive regulation of cellular component biogenesisGO:004408930.040
positive regulation of transportGO:005105020.040
cellular macromolecule metabolic processGO:00442603910.039
Human Mouse Rat Worm Fly
regulation of multicellular organism growthGO:004001440.038
autophagyGO:000691440.036
Fly
phagocytosisGO:000690930.035
cellular protein catabolic processGO:004425740.035
maintenance of locationGO:005123540.035
proteolysis involved in cellular protein catabolic processGO:005160330.034
organelle fusionGO:004828430.032
mitochondrion organizationGO:000700540.031
nitrogen compound metabolic processGO:00068073190.031
Fly
cellular nitrogen compound metabolic processGO:00346412900.031
Fly
organic substance biosynthetic processGO:19015762890.030
Fly
proteasomal protein catabolic processGO:001049820.030
ubiquitin dependent protein catabolic processGO:000651130.030
protein acetylationGO:000647320.030
Human
modification dependent protein catabolic processGO:001994130.029
single organism membrane fusionGO:004480120.029
membrane fusionGO:006102520.029
endosomal transportGO:001619720.029
nucleobase containing compound metabolic processGO:00061392740.028
cellular amine metabolic processGO:004410620.028
negative regulation of protein phosphorylationGO:000193340.028
amine metabolic processGO:000930820.027
positive regulation of catabolic processGO:000989640.027
modification dependent macromolecule catabolic processGO:004363230.027
cytokinesisGO:000091030.027
signal transductionGO:00071654550.027
Human Mouse Rat Worm Fly
positive regulation of cell cycleGO:004578730.027
cellular component morphogenesisGO:00329893360.027
nuclear transportGO:005116940.027
cellular aromatic compound metabolic processGO:00067252950.026
regulation of metabolic processGO:00192223590.026
Human Mouse Rat Worm Fly
organic cyclic compound metabolic processGO:19013603010.026
exocytosisGO:000688710.026
regulation of metal ion transportGO:001095940.026
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.025
neuron differentiationGO:00301823530.025
heterocycle metabolic processGO:00464832900.025
lipid storageGO:001991510.025
synaptic growth at neuromuscular junctionGO:005112420.025
protein acylationGO:004354330.025
Human
meiotic nuclear divisionGO:000712640.025
nucleocytoplasmic transportGO:000691340.025
generation of neuronsGO:00486993850.024
cell projection morphogenesisGO:00488582440.024
regulation of primary metabolic processGO:00800903110.024
Human Mouse Rat Worm Fly
regulation of nitrogen compound metabolic processGO:00511712510.024
Fly
internal protein amino acid acetylationGO:000647520.024
Human
transcription dna templatedGO:00063511810.024
cellular ketone metabolic processGO:0042180110.024
ribonucleoside monophosphate catabolic processGO:000915840.024
regulation of cellular amine metabolic processGO:003323800.023
regulation of cellular amino acid metabolic processGO:000652100.023
gene expressionGO:00104672520.023
regulation of establishment of protein localizationGO:007020140.023
sensory organ developmentGO:00074233930.023
Fly
protein importGO:001703830.023
regulation of cellular metabolic processGO:00313233200.023
Human Mouse Rat Worm Fly
internal peptidyl lysine acetylationGO:001839320.023
Human
regulation of response to stimulusGO:00485832690.023
Human Mouse Rat Worm Fly
purine nucleoside monophosphate catabolic processGO:000912840.023
regulation of macromolecule metabolic processGO:00602553170.023
Human Mouse Rat Worm Fly
cell projection organizationGO:00300302840.023
peptidyl lysine acetylationGO:001839420.022
Human
cognitionGO:005089010.022
protein metabolic processGO:00195381830.022
Human Mouse Rat Worm Fly
extrinsic apoptotic signaling pathwayGO:009719130.022
heterocycle biosynthetic processGO:00181302150.022
cell morphogenesisGO:00009022890.022
establishment of localizationGO:00512342440.022
guanosine containing compound metabolic processGO:190106840.022
organic cyclic compound biosynthetic processGO:19013622230.022
purine ribonucleoside monophosphate catabolic processGO:000916940.022
nucleoside monophosphate catabolic processGO:000912540.022
guanosine containing compound catabolic processGO:190106920.022
i kappab kinase nf kappab signalingGO:000724940.022
Human Mouse Rat Fly
regulation of developmental processGO:00507932470.022
stem cell maintenanceGO:001982740.021
regulation of signalingGO:00230512350.021
Human Mouse Rat Worm Fly
biosynthetic processGO:00090582940.021
Fly
gtp metabolic processGO:004603940.021
gtp catabolic processGO:000618420.021
rna metabolic processGO:00160702190.021
regulation of gene expressionGO:00104682650.021
regulation of protein transportGO:005122330.021
rna biosynthetic processGO:00327741810.021
cell part morphogenesisGO:00329902460.021
small molecule metabolic processGO:0044281770.021
single organism metabolic processGO:00447102170.021
Human Mouse Rat Worm Fly
cellular amino acid metabolic processGO:000652070.020
golgi vesicle transportGO:004819330.020
organic acid metabolic processGO:0006082310.020
regulation of protein modification by small protein conjugation or removalGO:190332030.020
rna localizationGO:000640340.020
nucleic acid templated transcriptionGO:00976591810.020
atp catabolic processGO:000620040.020
cellular response to external stimulusGO:007149620.020
protein localization to nucleusGO:003450430.020
carboxylic acid metabolic processGO:0019752220.020
regulation of protein catabolic processGO:004217610.020
aromatic compound biosynthetic processGO:00194382170.020
nucleic acid metabolic processGO:00903042440.020
negative regulation of biological processGO:00485193040.019
Mouse
regulation of cytoplasmic transportGO:190364940.019
regulation of cellular ketone metabolic processGO:001056570.019
single organism nuclear importGO:190259330.019
regulation of synaptic plasticityGO:004816710.019
positive regulation of cellular catabolic processGO:003133130.019
response to drugGO:004249330.019
oxoacid metabolic processGO:0043436310.019
regulation of rna metabolic processGO:00512522240.019
response to external stimulusGO:00096052640.019
Fly
nucleobase containing compound biosynthetic processGO:00346542050.019
nuclear importGO:005117030.019
regulation of nucleobase containing compound metabolic processGO:00192192500.019
response to chemicalGO:00422213200.019
Mouse Fly
regulation of protein complex assemblyGO:004325430.019
Mouse
regulation of protein ubiquitinationGO:003139630.018
protein targeting to nucleusGO:004474430.018
negative regulation of protein kinase activityGO:000646940.018
tissue remodelingGO:004877140.018
regulation of cell communicationGO:00106462320.018
Human Mouse Rat Worm Fly
regulation of stem cell proliferationGO:007209120.018
cellular biosynthetic processGO:00442492860.018
Fly
regulation of cell activationGO:005086510.018
negative regulation of kinase activityGO:003367340.018
regulation of synapse organizationGO:005080730.018
cellular response to nutrient levelsGO:003166920.018
regulation of transcription dna templatedGO:00063552130.018
regulation of cytokine productionGO:000181730.018
Human
immune system processGO:00023762410.018
Human Fly
regulation of rna biosynthetic processGO:20011412130.018
carboxylic acid catabolic processGO:004639530.018
regulation of signal transductionGO:00099662250.018
Human Mouse Rat Worm Fly
negative regulation of cellular processGO:00485232830.018
Mouse
neuron developmentGO:00486662620.018
cell surface receptor signaling pathwayGO:00071663250.018
Mouse
meiotic cell cycle processGO:190304630.018
morphogenesis of an epitheliumGO:00020093330.018
Mouse Fly
cellular nitrogen compound biosynthetic processGO:00442712180.018
Fly
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.018
Human
neuron projection morphogenesisGO:00488121610.018
response to stressGO:00069502630.018
Human Mouse Worm Fly
locomotionGO:00400113130.018
protein import into nucleusGO:000660630.018
regulation of nucleic acid templated transcriptionGO:19035062130.018
transportGO:00068102200.018
single organism localizationGO:19025782250.018
macromolecule modificationGO:00434121110.017
Human Mouse Rat Worm Fly
protein localization to plasma membraneGO:007265910.017
stem cell proliferationGO:007208940.017
regulation of nucleocytoplasmic transportGO:004682220.017
positive regulation of biological processGO:00485182530.017
Human Mouse Rat Worm Fly
cellular macromolecule biosynthetic processGO:00346452240.017
adult behaviorGO:003053420.017
positive regulation of secretionGO:005104710.017
germ line stem cell maintenanceGO:003071820.017
regulation of erk1 and erk2 cascadeGO:007037240.017
cellular component movementGO:00069283350.017
embryonic organ developmentGO:00485683810.017
regulation of autophagyGO:001050630.017
Fly
regulation of neural precursor cell proliferationGO:200017730.017
regulation of intracellular protein transportGO:003315730.017
positive regulation of protein complex assemblyGO:003133420.017
regulation of protein targetingGO:190353320.017
response to uvGO:000941130.017
organic acid catabolic processGO:001605430.017
eye developmentGO:00016542770.017
Fly
cellular response to extracellular stimulusGO:003166820.017
macromolecule biosynthetic processGO:00090592270.017
leukocyte proliferationGO:007066110.017
embryo development ending in birth or egg hatchingGO:00097922710.017
Mouse Worm Fly
regulation of cellular biosynthetic processGO:00313262450.017
Fly
heart developmentGO:00075073130.016
regulation of dendrite developmentGO:005077330.016
mononuclear cell proliferationGO:003294310.016
regulation of cell shapeGO:000836010.016
cytoplasm organizationGO:000702840.016
cellular protein modification processGO:00064641000.016
Human Mouse Rat Worm Fly
negative regulation of catabolic processGO:000989530.016
central nervous system developmentGO:00074173870.016
regulation of purine nucleotide catabolic processGO:003312120.016
neuron projection developmentGO:00311751800.016
regulation of bindingGO:005109830.016
synaptic vesicle transportGO:004848910.016
organelle organizationGO:00069962270.016
Human
positive regulation of dna metabolic processGO:005105410.016
cell substrate adhesionGO:003158940.016
erk1 and erk2 cascadeGO:007037140.016
developmental growthGO:00485891660.016
double strand break repair via homologous recombinationGO:000072410.016
cellular protein metabolic processGO:00442671290.016
Human Mouse Rat Worm Fly
positive regulation of secretion by cellGO:190353210.016
regulation of multicellular organismal processGO:00512392770.016
Human
single organism organelle organizationGO:19025891990.016
Human
vacuolar transportGO:000703420.016
regulation of extrinsic apoptotic signaling pathwayGO:200123630.016
cytoskeleton dependent cytokinesisGO:006164030.016
neuron neuron synaptic transmissionGO:000727010.016
rna modificationGO:000945120.016
cellular response to starvationGO:000926710.016
tube morphogenesisGO:00352393490.015
Mouse Worm
female sex differentiationGO:004666040.015
compound eye developmentGO:004874920.015
Fly
microtubule organizing center organizationGO:003102310.015
cellular component assemblyGO:00226071700.015
Mouse
protein dephosphorylationGO:000647030.015
hemopoiesisGO:00300971830.015
cellular carbohydrate metabolic processGO:004426240.015
vasculature developmentGO:00019442780.015
cellular amide metabolic processGO:004360340.015
Fly
peptidyl serine modificationGO:001820920.015
regulation of macromolecule biosynthetic processGO:00105562250.015
adherens junction organizationGO:003433240.015
cortical cytoskeleton organizationGO:003086510.015
regulation of protein import into nucleusGO:004230620.015
negative regulation of mapk cascadeGO:004340940.015
protein polyubiquitinationGO:000020940.015
regulation of nucleoside metabolic processGO:000911820.015
regulation of protein localization to nucleusGO:190018020.015
double strand break repairGO:000630230.015
synaptic vesicle localizationGO:009747910.015
negative regulation of nuclear divisionGO:005178430.015
cellular response to radiationGO:007147840.015
secondary metabolic processGO:001974830.015
positive regulation of immune effector processGO:000269930.015
Human Fly
regulation of synapse assemblyGO:005196330.015
organonitrogen compound metabolic processGO:1901564740.015
Fly
single organism transportGO:00447652060.015
negative regulation of protein transportGO:005122430.015
neurotransmitter transportGO:000683620.015
cellular component biogenesisGO:00440851780.015
Mouse
locomotor rhythmGO:004547530.015
regulation of reproductive processGO:200024140.015
regulation of nucleotide catabolic processGO:003081120.015
protein modification processGO:00362111000.015
Human Mouse Rat Worm Fly
negative regulation of cellular catabolic processGO:003133030.014
regulation of biological qualityGO:00650082630.014
peptidyl serine phosphorylationGO:001810510.014
regulation of calcium ion transportGO:005192420.014
single fertilizationGO:000733830.014
g1 s transition of mitotic cell cycleGO:000008210.014
small molecule catabolic processGO:004428230.014
positive regulation of cellular amine metabolic processGO:003324000.014
primary neural tube formationGO:001402010.014
positive regulation of cell activationGO:005086710.014
growthGO:00400071740.014
positive regulation of cellular amino acid metabolic processGO:004576400.014
neuroblast proliferationGO:000740520.014
positive regulation of i kappab kinase nf kappab signalingGO:004312330.014
Human Mouse Rat
protein secretionGO:000930610.014
regulation of peptidyl tyrosine phosphorylationGO:005073010.014
regulation of transporter activityGO:003240920.014
establishment of synaptic vesicle localizationGO:009748010.014
sequestering of calcium ionGO:005120830.014
regulation of stem cell differentiationGO:200073640.014
interspecies interaction between organismsGO:004441940.014
cellular component disassemblyGO:002241110.014
fatty acid catabolic processGO:000906210.014
regulation of biosynthetic processGO:00098892500.014
Fly
regulation of mrna processingGO:005068430.014
regulation of cellular macromolecule biosynthetic processGO:20001122220.014
positive regulation of purine nucleotide catabolic processGO:003312310.014
centrosome organizationGO:005129710.014
protein heterooligomerizationGO:005129110.014
regulation of meiotic cell cycleGO:005144510.014
positive regulation of cytoskeleton organizationGO:005149530.013
lymphocyte proliferationGO:004665110.013
regulation of dendrite morphogenesisGO:004881430.013
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
symbiosis encompassing mutualism through parasitismGO:004440340.013
cell cycle g1 s phase transitionGO:004484310.013
regulation of i kappab kinase nf kappab signalingGO:004312240.013
Human Mouse Rat
establishment of protein localization to plasma membraneGO:009000210.013
positive regulation of nucleotide catabolic processGO:003081310.013
positive regulation of lymphocyte mediated immunityGO:000270810.013
Human
cell morphogenesis involved in differentiationGO:00009041950.013
b cell activationGO:004211320.013
intracellular mrna localizationGO:000829810.013
spermatid differentiationGO:004851520.013
blood vessel morphogenesisGO:00485142160.013
oocyte anterior posterior axis specificationGO:000731440.013
lipid catabolic processGO:001604240.013
cell migrationGO:00164772370.013
axon developmentGO:00615641660.013
regulation of neuronal synaptic plasticityGO:004816810.013
production of molecular mediator of immune responseGO:000244020.013
Human Fly
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
cell morphogenesis involved in neuron differentiationGO:00486671630.013
regulation of gtpase activityGO:004308720.013
regionalizationGO:00030022740.013
phosphate containing compound metabolic processGO:00067961080.013
Human Mouse Rat Worm Fly
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.013
mitotic cytokinesisGO:000028130.013
regulation of multicellular organismal developmentGO:20000262230.013
head developmentGO:00603223030.013
regulation of response to biotic stimulusGO:000283120.013
Fly
regulation of cellular protein catabolic processGO:190336210.013
system processGO:00030081850.013
tube closureGO:006060610.012
fertilizationGO:000956630.012
alcohol biosynthetic processGO:004616520.012
positive regulation of erk1 and erk2 cascadeGO:007037420.012
viral processGO:001603210.012
neurotransmitter secretionGO:000726920.012
cellular response to oxygen levelsGO:007145310.012
cellular response to chemical stimulusGO:00708871570.012
Mouse Fly
lateral inhibitionGO:004633110.012
membrane invaginationGO:001032410.012
immune system developmentGO:00025201910.012
negative regulation of protein serine threonine kinase activityGO:007190120.012
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
recombinational repairGO:000072510.012
transcription elongation from rna polymerase ii promoterGO:000636830.012
phagocytosis engulfmentGO:000691110.012
regulation of mrna splicing via spliceosomeGO:004802430.012
positive regulation of apoptotic signaling pathwayGO:200123510.012
regulation of sequestering of calcium ionGO:005128240.012
mitotic dna integrity checkpointGO:004477440.012
lipid homeostasisGO:005508830.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
response to monosaccharideGO:003428430.012
macromolecular complex disassemblyGO:003298410.012
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.012
mitochondrial transportGO:000683920.012
negative regulation of cytokine productionGO:000181810.012
actin filament polymerizationGO:003004120.012
regulation of dna replicationGO:000627530.012
positive regulation of cellular processGO:00485222010.012
Human Mouse Rat Worm Fly
axonogenesisGO:00074091520.012
cytokinetic processGO:003250620.012
positive regulation of gtp catabolic processGO:003312610.012
response to hydrogen peroxideGO:004254230.012
digestive tract morphogenesisGO:00485462310.012
Worm
positive regulation of gtpase activityGO:004354710.012
blood vessel developmentGO:00015682460.012
spermatid developmentGO:000728620.012
camera type eye developmentGO:00430102220.012
phosphorus metabolic processGO:00067931090.012
Human Mouse Rat Worm Fly
regulation of inflammatory responseGO:005072720.012
stem cell divisionGO:001714510.012
negative regulation of signal transductionGO:0009968940.012
Mouse
transcription from rna polymerase ii promoterGO:0006366800.012
macroautophagyGO:001623610.012
response to carbohydrateGO:000974330.012
nuclear exportGO:005116810.011
positive regulation of chromatin modificationGO:190331010.011
multi organism cellular processGO:004476420.011
regulation of epithelial cell proliferationGO:005067830.011
somatic muscle developmentGO:000752540.011
negative regulation of cytoplasmic transportGO:190365020.011
endosome organizationGO:000703220.011
fatty acid oxidationGO:001939510.011
positive regulation of chromosome organizationGO:200125210.011
chordate embryonic developmentGO:00430092710.011
Mouse
glucose homeostasisGO:004259310.011
response to hexoseGO:000974630.011
protein homooligomerizationGO:005126030.011
negative regulation of sequestering of calcium ionGO:005128340.011
antimicrobial humoral responseGO:001973020.011
Fly
cellular response to decreased oxygen levelsGO:003629410.011
positive regulation of nucleoside metabolic processGO:004597910.011
signal transduction in absence of ligandGO:003803410.011
rna 3 end processingGO:003112320.011
sequestering of metal ionGO:005123830.011
cellular modified amino acid metabolic processGO:000657530.011
carbohydrate homeostasisGO:003350010.011
nucleic acid transportGO:005065720.011
localization of cellGO:00516742440.011
positive regulation of cell adhesionGO:004578510.011
digestive tract developmentGO:00485652650.011
Worm
cellular response to hypoxiaGO:007145610.011
response to topologically incorrect proteinGO:003596620.011
regulation of ion transmembrane transporter activityGO:003241220.011
dna templated transcription elongationGO:000635430.011
cellular response to biotic stimulusGO:007121630.011
Fly
lipid oxidationGO:003444010.011
regulation of chromosome segregationGO:005198310.011
cellular transition metal ion homeostasisGO:004691630.011
cellular respirationGO:004533330.011
female gonad developmentGO:000858540.011
response to glucocorticoidGO:005138410.010
cell matrix adhesionGO:000716040.010
calcium ion transport into cytosolGO:006040230.010
protein complex disassemblyGO:004324110.010
meiotic chromosome segregationGO:004513230.010
development of primary female sexual characteristicsGO:004654540.010
regulation of transmembrane transporter activityGO:002289820.010
regulation of cell differentiationGO:00455951420.010
response to glucoseGO:000974930.010
peptide metabolic processGO:000651810.010
Fly
negative regulation of intracellular transportGO:003238730.010
release of sequestered calcium ion into cytosolGO:005120930.010
cellular response to organic substanceGO:00713101050.010
Mouse Fly
cellular lipid catabolic processGO:004424230.010
regulation of microtubule cytoskeleton organizationGO:007050730.010
negative regulation of multi organism processGO:004390130.010
regulation of dna templated transcription elongationGO:003278430.010
brain developmentGO:00074202930.010
positive regulation of translationGO:004572710.010
post golgi vesicle mediated transportGO:000689210.010
cytosolic calcium ion transportGO:006040130.010
regulation of gtp catabolic processGO:003312420.010
dna catabolic processGO:000630810.010
negative regulation of response to stimulusGO:00485851040.010
Mouse
skeletal system developmentGO:00015011810.010
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.010
post embryonic organ developmentGO:004856940.010
Fly
response to nutrientGO:000758430.010
regulation of jak stat cascadeGO:004642530.010
cellular response to light stimulusGO:007148240.010
centrosome cycleGO:000709810.010
nucleobase containing compound transportGO:001593120.010
regulation of alternative mrna splicing via spliceosomeGO:000038110.010
positive regulation of cytokine productionGO:000181920.010
Human
regulation of organ growthGO:004662030.010
phosphorylationGO:0016310690.010
Human Mouse Rat Worm Fly

map3k7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.046
nervous system diseaseDOID:86300.022
musculoskeletal system diseaseDOID:1700.020
disease of metabolismDOID:001466700.019
disease of cellular proliferationDOID:1456600.014
organ system cancerDOID:005068600.013
cancerDOID:16200.013
muscular diseaseDOID:008000000.011
inherited metabolic disorderDOID:65500.011
muscle tissue diseaseDOID:6600.011
immune system diseaseDOID:291400.011
myopathyDOID:42300.011