Danio rerio

32 known processes

spi1l

spleen focus forming virus (SFFV) proviral integration oncogene spi1 like

(Aliases: MGC152991,zgc:152991)

spi1l biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
leukocyte differentiationGO:0002521250.442
regulation of metabolic processGO:00192223590.433
Zebrafish Mouse
embryonic organ developmentGO:00485683810.386
macrophage differentiationGO:003022570.321
Zebrafish Mouse
immune system processGO:00023762410.306
cellular amide metabolic processGO:004360340.276
myeloid leukocyte differentiationGO:0002573150.274
immune system developmentGO:00025201910.274
hematopoietic or lymphoid organ developmentGO:00485341910.254
embryonic hemopoiesisGO:0035162530.252
regulation of multicellular organismal developmentGO:20000262230.251
regulation of myeloid leukocyte differentiationGO:000276150.239
negative regulation of cellular processGO:00485232830.235
Zebrafish
definitive hemopoiesisGO:0060216180.219
response to external stimulusGO:00096052640.218
regulation of biological qualityGO:00650082630.214
Zebrafish
gene expressionGO:00104672520.209
Zebrafish Mouse
neuron developmentGO:00486662620.209
hemopoiesisGO:00300971830.197
tube morphogenesisGO:00352393490.191
myeloid cell differentiationGO:0030099860.180
regulation of primary metabolic processGO:00800903110.177
Mouse
cellular modified amino acid metabolic processGO:000657530.167
positive regulation of biological processGO:00485182530.148
Zebrafish
regulation of multicellular organismal processGO:00512392770.140
gland developmentGO:00487321430.131
negative regulation of biological processGO:00485193040.124
Zebrafish
cell surface receptor signaling pathwayGO:00071663250.124
regulation of developmental processGO:00507932470.124
macrophage chemotaxisGO:004824630.123
mesenchymal cell differentiationGO:0048762870.118
cellular response to lipopolysaccharideGO:007122230.117
segmentationGO:0035282970.110
cellular macromolecule metabolic processGO:00442603910.108
Mouse
compound eye developmentGO:004874920.106
cellular aromatic compound metabolic processGO:00067252950.105
Mouse
female gonad developmentGO:000858540.105
cellular response to molecule of bacterial originGO:007121930.103
heterocycle biosynthetic processGO:00181302150.103
Mouse
antimicrobial humoral responseGO:001973020.102
response to other organismGO:0051707970.101
monocyte differentiationGO:003022420.100
transmembrane transportGO:00550851200.097
cell morphogenesis involved in neuron differentiationGO:00486671630.094
regulation of macromolecule metabolic processGO:00602553170.094
Zebrafish Mouse
regulation of gene expressionGO:00104682650.093
Zebrafish Mouse
response to drugGO:004249330.090
cellular nitrogen compound metabolic processGO:00346412900.087
Mouse
rna metabolic processGO:00160702190.087
Mouse
establishment of localizationGO:00512342440.086
regulation of cellular metabolic processGO:00313233200.085
Mouse
larval developmentGO:000216420.082
development of primary female sexual characteristicsGO:004654540.082
regulation of sequence specific dna binding transcription factor activityGO:005109090.080
nucleic acid metabolic processGO:00903042440.078
Mouse
liver developmentGO:0001889960.078
response to chemicalGO:00422213200.078
signal transductionGO:00071654550.077
regulation of immune system processGO:0002682340.077
multicellular organismal metabolic processGO:004423620.076
embryonic heart tube developmentGO:00350501330.074
locomotionGO:00400113130.072
cell deathGO:00082191210.072
regulation of cell deathGO:00109411030.070
peptide metabolic processGO:000651810.067
digestive tract morphogenesisGO:00485462310.067
regulation of inflammatory responseGO:005072720.067
fin developmentGO:0033333770.066
nitrogen compound metabolic processGO:00068073190.066
Mouse
regulation of cell differentiationGO:00455951420.064
heart developmentGO:00075073130.063
female sex differentiationGO:004666040.063
response to nutrientGO:000758430.061
heterocycle metabolic processGO:00464832900.060
Mouse
positive regulation of cytokine productionGO:000181920.059
regulation of biosynthetic processGO:00098892500.059
Mouse
blood vessel developmentGO:00015682460.058
appendage developmentGO:0048736800.058
regulation of cellular macromolecule biosynthetic processGO:20001122220.058
Mouse
head developmentGO:00603223030.057
specification of symmetryGO:00097992040.057
tissue remodelingGO:004877140.056
regulation of cell activationGO:005086510.056
regulation of response to stressGO:0080134360.056
neuron differentiationGO:00301823530.056
regulation of synapse assemblyGO:005196330.055
vasculature developmentGO:00019442780.053
organonitrogen compound metabolic processGO:1901564740.053
regulation of myeloid cell differentiationGO:004563780.052
taxisGO:00423301090.052
primitive hemopoiesisGO:0060215270.052
positive regulation of jak stat cascadeGO:004642720.052
activation of immune responseGO:000225390.052
intracellular signal transductionGO:0035556850.052
regulation of cell communicationGO:00106462320.051
organic substance biosynthetic processGO:19015762890.051
Mouse
positive regulation of defense responseGO:003134990.051
regulation of cytokine productionGO:000181730.051
cellular response to external stimulusGO:007149620.050
morphogenesis of an epitheliumGO:00020093330.050
regulation of nucleic acid templated transcriptionGO:19035062130.050
Mouse
neuron neuron synaptic transmissionGO:000727010.049
system processGO:00030081850.049
digestive tract developmentGO:00485652650.048
cellular nitrogen compound biosynthetic processGO:00442712180.048
Mouse
cell morphogenesisGO:00009022890.046
digestive system developmentGO:00551232890.046
transportGO:00068102200.045
central nervous system developmentGO:00074173870.044
single organism localizationGO:19025782250.043
hepaticobiliary system developmentGO:0061008980.043
muscle cell differentiationGO:00426921390.043
positive regulation of cell activationGO:005086710.043
phagocytosisGO:000690930.042
generation of neuronsGO:00486993850.042
regulation of neurogenesisGO:0050767870.042
regulation of hormone secretionGO:004688320.042
cell projection organizationGO:00300302840.041
regulation of rna metabolic processGO:00512522240.041
Mouse
neutrophil differentiationGO:003022360.041
Zebrafish
regulation of nitrogen compound metabolic processGO:00511712510.041
Mouse
positive regulation of cellular catabolic processGO:003133130.040
regulation of stem cell differentiationGO:200073640.040
somitogenesisGO:0001756870.040
regulation of neuron projection developmentGO:0010975400.039
positive regulation of map kinase activityGO:004340630.039
granulocyte differentiationGO:003085180.038
Zebrafish
positive regulation of cellular component biogenesisGO:004408930.037
response to woundingGO:00096111160.037
transcription dna templatedGO:00063511810.037
Mouse
positive regulation of inflammatory responseGO:005072910.037
maintenance of locationGO:005123540.036
regulation of chronic inflammatory responseGO:000267610.036
positive regulation of cellular extravasationGO:000269310.036
cellular response to chemical stimulusGO:00708871570.035
cellular response to decreased oxygen levelsGO:003629410.035
nucleic acid templated transcriptionGO:00976591810.035
Mouse
regionalizationGO:00030022740.035
regulation of rna biosynthetic processGO:20011412130.034
Mouse
agingGO:000756820.034
b cell differentiationGO:003018310.034
regulation of reproductive processGO:200024140.034
response to external biotic stimulusGO:0043207970.034
anterior posterior pattern specificationGO:00099521520.034
cartilage developmentGO:0051216960.034
regulation of response to stimulusGO:00485832690.034
defense responseGO:0006952470.033
organic cyclic compound metabolic processGO:19013603010.033
Mouse
b cell activationGO:004211320.032
positive regulation of chronic inflammatory responseGO:000267810.032
regulation of molecular functionGO:0065009700.032
aromatic compound biosynthetic processGO:00194382170.032
Mouse
negative regulation of map kinase activityGO:004340720.032
cognitionGO:005089010.032
sensory organ developmentGO:00074233930.031
regulation of bone remodelingGO:004685020.031
negative regulation of myeloid leukocyte differentiationGO:000276210.031
Zebrafish
single organism transportGO:00447652060.031
guanosine containing compound metabolic processGO:190106840.031
angiogenesisGO:00015251580.031
hematopoietic stem cell differentiationGO:0060218200.031
small molecule metabolic processGO:0044281770.030
regulation of protein complex assemblyGO:004325430.030
cellular response to biotic stimulusGO:007121630.030
regulation of jak stat cascadeGO:004642530.030
extrinsic apoptotic signaling pathwayGO:009719130.029
leukocyte chemotaxisGO:0030595120.029
negative regulation of multicellular organismal processGO:0051241690.029
Zebrafish
neutrophil migrationGO:1990266100.029
granulocyte migrationGO:0097530110.029
positive regulation of nucleobase containing compound metabolic processGO:0045935690.029
muscle cell developmentGO:00550011150.029
regulation of metal ion transportGO:001095940.028
positive regulation of developmental processGO:0051094500.028
calcium ion homeostasisGO:0055074190.028
myeloid leukocyte migrationGO:0097529120.028
muscle structure developmentGO:00610611960.028
localization of cellGO:00516742440.028
regulation of neurotransmitter transportGO:005158810.028
activation of mapk activityGO:000018730.028
positive regulation of nitrogen compound metabolic processGO:0051173690.028
regulation of cell projection organizationGO:0031344440.028
single organism metabolic processGO:00447102170.028
cellular component movementGO:00069283350.027
positive regulation of macromolecule metabolic processGO:0010604930.027
Zebrafish
cell motilityGO:00488702440.027
negative regulation of cell communicationGO:0010648960.026
regulation of cellular biosynthetic processGO:00313262450.026
Mouse
cellular macromolecule biosynthetic processGO:00346452240.026
Mouse
axis specificationGO:0009798430.026
cation homeostasisGO:0055080330.026
regulation of response to external stimulusGO:0032101310.026
positive regulation of response to stimulusGO:0048584800.026
determination of heart left right asymmetryGO:00613711170.026
regulation of catalytic activityGO:0050790550.026
regulation of neuron differentiationGO:0045664560.025
epidermal cell fate specificationGO:000995740.025
positive regulation of cellular processGO:00485222010.025
epithelial tube morphogenesisGO:00605621480.025
erythrocyte differentiationGO:0030218540.025
Zebrafish
hematopoietic progenitor cell differentiationGO:0002244230.025
axon developmentGO:00615641660.025
biosynthetic processGO:00090582940.025
Mouse
protein secretionGO:000930610.025
regulation of phosphate metabolic processGO:0019220430.025
response to stressGO:00069502630.025
positive regulation of response to woundingGO:190303650.024
response to amino acidGO:004320020.024
guanosine containing compound catabolic processGO:190106920.024
negative regulation of cell deathGO:0060548600.024
negative regulation of metabolic processGO:0009892860.024
negative regulation of programmed cell deathGO:0043069580.024
response to biotic stimulusGO:0009607970.024
regulation of cell developmentGO:00602841000.024
monocarboxylic acid catabolic processGO:007232930.024
regulation of wnt signaling pathwayGO:0030111530.023
nucleocytoplasmic transportGO:000691340.023
stem cell developmentGO:0048864820.023
hatching gland developmentGO:004878530.023
gtp catabolic processGO:000618420.023
regulation of signalingGO:00230512350.023
negative regulation of leukocyte differentiationGO:190210610.023
Zebrafish
nucleobase containing compound metabolic processGO:00061392740.023
Mouse
regulation of cellular amine metabolic processGO:003323800.023
positive regulation of multicellular organismal processGO:0051240520.023
regulation of tissue remodelingGO:003410320.023
endocrine system developmentGO:0035270650.022
determination of left right symmetryGO:00073681790.022
regulation of nucleotide catabolic processGO:003081120.022
regulation of canonical wnt signaling pathwayGO:0060828340.022
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.022
negative regulation of protein maturationGO:1903318100.021
ion transmembrane transportGO:0034220910.021
cytokinesisGO:000091030.021
adherens junction organizationGO:003433240.021
regulation of erythrocyte differentiationGO:004564620.021
Zebrafish
positive regulation of secretion by cellGO:190353210.021
connective tissue developmentGO:0061448990.021
regulation of neutrophil differentiationGO:004565830.021
Zebrafish
multicellular organismal response to stressGO:003355520.021
proteolysisGO:0006508380.020
cell cycleGO:0007049930.020
response to amphetamineGO:000197510.020
regulation of synapse organizationGO:005080730.020
astrocyte differentiationGO:004870810.020
cell migrationGO:00164772370.020
gtp metabolic processGO:004603940.020
inflammatory responseGO:000695480.020
cellular response to stressGO:0033554620.020
sequestering of calcium ionGO:005120830.020
neuron projection developmentGO:00311751800.020
positive regulation of nucleic acid templated transcriptionGO:1903508570.020
leukocyte proliferationGO:007066110.020
positive regulation of transportGO:005105020.019
regulation of transcription dna templatedGO:00063552130.019
Mouse
striated muscle cell differentiationGO:00511461290.019
rna biosynthetic processGO:00327741810.019
Mouse
ventricular cardiac muscle tissue developmentGO:000322930.019
cellular biosynthetic processGO:00442492860.019
Mouse
bone remodelingGO:004684920.019
positive regulation of cellular amino acid metabolic processGO:004576400.019
respiratory system developmentGO:006054150.019
negative regulation of stem cell differentiationGO:200073720.019
pancreas developmentGO:0031016840.019
regulation of anatomical structure morphogenesisGO:00226031300.019
nucleobase containing compound biosynthetic processGO:00346542050.019
Mouse
regulation of immune effector processGO:000269750.019
positive regulation of canonical wnt signaling pathwayGO:009026340.019
muscle fiber developmentGO:0048747520.019
negative regulation of apoptotic processGO:0043066550.019
regulation of cellular extravasationGO:000269110.019
positive regulation of metabolic processGO:00098931080.018
Zebrafish
regulation of nucleobase containing compound metabolic processGO:00192192500.018
Mouse
negative regulation of molecular functionGO:0044092230.018
negative regulation of myeloid cell differentiationGO:004563810.018
Zebrafish
positive regulation of nucleotide catabolic processGO:003081310.018
regulation of defense responseGO:0031347140.018
lateral line developmentGO:0048882660.018
fat soluble vitamin metabolic processGO:000677540.018
canonical wnt signaling pathwayGO:0060070480.018
lipid storageGO:001991510.018
skeletal system developmentGO:00015011810.018
neurotransmitter transportGO:000683620.018
cellular response to extracellular stimulusGO:003166820.018
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.018
cell morphogenesis involved in differentiationGO:00009041950.018
outflow tract morphogenesisGO:000315110.018
regulation of apoptotic processGO:0042981980.017
regulation of sequestering of calcium ionGO:005128240.017
negative regulation of biosynthetic processGO:0009890550.017
leukocyte migrationGO:0050900150.017
deathGO:00162651210.017
atp catabolic processGO:000620040.017
embryonic organ morphogenesisGO:00485622740.017
positive regulation of muscle organ developmentGO:004863610.017
negative regulation of secretion by cellGO:190353120.017
cellular response to hypoxiaGO:007145610.017
transcription from rna polymerase ii promoterGO:0006366800.017
organic acid metabolic processGO:0006082310.017
amine metabolic processGO:000930820.017
organelle organizationGO:00069962270.017
blood vessel morphogenesisGO:00485142160.017
response to glucocorticoidGO:005138410.017
cellular response to oxygen levelsGO:007145310.017
chemotaxisGO:00069351040.017
negative regulation of muscle cell differentiationGO:005114810.017
negative regulation of gene expressionGO:0010629650.016
negative regulation of response to stimulusGO:00485851040.016
regulation of programmed cell deathGO:00430671010.016
protein metabolic processGO:00195381830.016
somatic stem cell maintenanceGO:003501910.016
ion homeostasisGO:0050801410.016
regulation of cellular amino acid metabolic processGO:000652100.016
regulation of protein catabolic processGO:004217610.016
neural crest cell differentiationGO:0014033720.016
regulation of multicellular organism growthGO:004001440.016
cortical cytoskeleton organizationGO:003086510.016
intracellular mrna localizationGO:000829810.016
cardiac atrium morphogenesisGO:000320920.016
cellular response to nutrient levelsGO:003166920.016
positive regulation of gene expressionGO:0010628710.016
Zebrafish
cytoskeleton dependent cytokinesisGO:006164030.015
spermatid differentiationGO:004851520.015
dna modificationGO:000630480.015
regulation of response to woundingGO:1903034110.015
macromolecule biosynthetic processGO:00090592270.015
Mouse
regulation of nervous system developmentGO:0051960900.015
positive regulation of protein complex assemblyGO:003133420.015
regulation of postsynaptic membrane potentialGO:006007810.015
regulation of signal transductionGO:00099662250.015
cell chemotaxisGO:0060326170.015
regulation of heart growthGO:006042020.015
regulation of cell shapeGO:000836010.015
regulation of extrinsic apoptotic signaling pathwayGO:200123630.015
heart loopingGO:0001947940.015
spermatid developmentGO:000728620.015
negative regulation of macromolecule metabolic processGO:0010605760.015
tube closureGO:006060610.014
myeloid cell homeostasisGO:0002262560.014
Zebrafish
negative regulation of secretionGO:005104820.014
synaptic growth at neuromuscular junctionGO:005112420.014
sprouting angiogenesisGO:0002040530.014
primitive erythrocyte differentiationGO:006031950.014
positive regulation of striated muscle tissue developmentGO:004584410.014
multicellular organism growthGO:003526440.014
negative regulation of catabolic processGO:000989530.014
striated muscle cell developmentGO:00550021080.014
positive regulation of axon regenerationGO:004868030.014
cation transmembrane transportGO:0098655650.014
response to organic substanceGO:00100331530.014
negative regulation of hormone secretionGO:004688820.014
lipid catabolic processGO:001604240.014
regulation of production of molecular mediator of immune responseGO:000270010.014
erythrocyte maturationGO:004324980.014
multi organism processGO:00517041340.014
negative regulation of chromosome organizationGO:200125110.014
lateral inhibitionGO:004633110.014
gas transportGO:001566930.013
organ formationGO:0048645170.013
homeostasis of number of cellsGO:0048872620.013
Zebrafish
sensory perception of chemical stimulusGO:000760630.013
positive regulation of leukocyte differentiationGO:190210710.013
cortical actin cytoskeleton organizationGO:003086610.013
nerve developmentGO:0021675450.013
negative regulation of nitrogen compound metabolic processGO:0051172590.013
regulation of organ growthGO:004662030.013
response to alkaloidGO:004327920.013
gastrulationGO:00073692080.013
regulation of cytoplasmic transportGO:190364940.013
apoptotic processGO:00069151160.013
regulation of bindingGO:005109830.013
stem cell differentiationGO:00488631170.013
regulation of synaptic plasticityGO:004816710.013
blood circulationGO:0008015870.013
response to foodGO:003209410.013
response to nitrogen compoundGO:1901698190.013
regulation of neurotransmitter secretionGO:004692810.012
regulation of hematopoietic progenitor cell differentiationGO:190153210.012
positive regulation of translationGO:004572710.012
cellular response to starvationGO:000926710.012
somite developmentGO:0061053960.012
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.012
regulation of transmembrane transporter activityGO:002289820.012
negative regulation of nuclear divisionGO:005178430.012
lymph vessel developmentGO:0001945270.012
jak stat cascadeGO:000725950.012
positive regulation of molecular functionGO:0044093330.012
positive regulation of tyrosine phosphorylation of stat3 proteinGO:004251710.012
oxoacid metabolic processGO:0043436310.012
neurotransmitter secretionGO:000726920.012
phagocytosis engulfmentGO:000691110.012
cellular amine metabolic processGO:004410620.012
toll like receptor signaling pathwayGO:000222440.012
cardiac muscle tissue morphogenesisGO:005500870.012
cytoplasm organizationGO:000702840.012
receptor internalizationGO:003162320.012
regulation of purine nucleotide catabolic processGO:003312120.012
regulation of translational initiationGO:000644610.012
positive regulation of cellular amine metabolic processGO:003324000.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
regulation of gtp catabolic processGO:003312420.012
axis elongation involved in somitogenesisGO:009024520.012
positive regulation of neuron differentiationGO:0045666120.012
regulation of cardiac muscle tissue developmentGO:005502410.012
cellular response to cytokine stimulusGO:007134570.012
actin filament polymerizationGO:003004120.012
protein import into nucleusGO:000660630.012
regulation of protein polymerizationGO:003227120.012
regulation of transporter activityGO:003240920.012
rna localizationGO:000640340.012
circulatory system processGO:0003013870.012
enzyme linked receptor protein signaling pathwayGO:00071671060.012
anterior posterior axis specificationGO:0009948200.012
collagen biosynthetic processGO:003296420.012
actin filament based movementGO:003004810.012
mitochondrion organizationGO:000700540.012
single organism biosynthetic processGO:0044711710.012
negative regulation of rna metabolic processGO:0051253480.012
glial cell migrationGO:000834730.012
cellular lipid catabolic processGO:004424230.012
positive regulation of immune system processGO:0002684170.011
regulation of skeletal muscle tissue developmentGO:004864140.011
positive regulation of neuron projection regenerationGO:007057230.011
metal ion homeostasisGO:0055065260.011
positive regulation of cell differentiationGO:0045597300.011
behaviorGO:0007610740.011
regulation of protein transportGO:005122330.011
negative regulation of cytokine productionGO:000181810.011
carbohydrate derivative metabolic processGO:1901135610.011
regulation of tyrosine phosphorylation of stat proteinGO:004250910.011
protein polymerizationGO:005125840.011
cardiac cell fate commitmentGO:006091110.011
positive regulation of muscle tissue developmentGO:190186310.011
positive regulation of rna metabolic processGO:0051254590.011
negative regulation of sequestering of calcium ionGO:005128340.011
inositol lipid mediated signalingGO:004801720.011
regulation of epithelial cell proliferationGO:005067830.011
sequestering of metal ionGO:005123830.011
negative regulation of mapk cascadeGO:004340940.011
cellular amino acid metabolic processGO:000652070.011
regulation of membrane potentialGO:0042391230.011
cranial ganglion developmentGO:006155030.011
calcium mediated signalingGO:001972220.011
erythrocyte developmentGO:0048821240.011
Zebrafish
protein targeting to nucleusGO:004474430.011
muscle hypertrophyGO:001489620.011
positive regulation of immune effector processGO:000269930.011
negative regulation of immune responseGO:005077720.011
regulation of protein bindingGO:004339330.011
neutrophil chemotaxisGO:0030593100.011
positive regulation of cellular metabolic processGO:0031325940.011
nucleotide metabolic processGO:0009117280.011
translational initiationGO:000641330.010
purine containing compound metabolic processGO:0072521290.010
developmental growth involved in morphogenesisGO:0060560860.010
regulation of cellular ketone metabolic processGO:001056570.010
regulation of establishment of planar polarityGO:009017540.010
sodium ion importGO:009736930.010
negative regulation of peptidase activityGO:0010466100.010
endodermal cell fate determinationGO:000749320.010
lymphocyte proliferationGO:004665110.010
positive regulation of secretionGO:005104710.010
regulation of protein ubiquitinationGO:003139630.010
purine nucleoside monophosphate catabolic processGO:000912840.010
negative regulation of nucleic acid templated transcriptionGO:1903507450.010
anatomical structure homeostasisGO:0060249360.010
bicarbonate transportGO:001570140.010
macromolecule modificationGO:00434121110.010
positive regulation of cell adhesionGO:004578510.010
endosomal transportGO:001619720.010
hypothalamus cell differentiationGO:002197940.010
homeostatic processGO:00425921420.010
Zebrafish
negative regulation of defense responseGO:003134820.010
neuron deathGO:0070997210.010

spi1l disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
eye diseaseDOID:561400.040
eye and adnexa diseaseDOID:149200.040
nervous system diseaseDOID:86300.040
disease of anatomical entityDOID:700.040
sensory system diseaseDOID:005015500.040
inherited metabolic disorderDOID:65500.020
disease of metabolismDOID:001466700.020
cardiovascular system diseaseDOID:128700.013