Danio rerio

0 known processes

ube2w

ubiquitin-conjugating enzyme E2W (putative)

(Aliases: im:6905459,si:ch211-193n21.4)

ube2w biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.068
maintenance of locationGO:005123540.046
positive regulation of transportGO:005105020.046
agingGO:000756820.045
ubiquitin dependent protein catabolic processGO:000651130.035
Mouse
cellular protein catabolic processGO:004425740.035
Mouse
protein localization to plasma membraneGO:007265910.034
modification dependent protein catabolic processGO:001994130.033
Mouse
multicellular organism growthGO:003526440.033
establishment of protein localization to organelleGO:007259440.032
phagocytosisGO:000690930.032
lipid storageGO:001991510.032
signal transductionGO:00071654550.031
regulation of protein complex assemblyGO:004325430.031
proteolysis involved in cellular protein catabolic processGO:005160330.030
Mouse
amine metabolic processGO:000930820.030
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.028
Mouse
autophagyGO:000691440.028
single organism localizationGO:19025782250.028
regulation of multicellular organism growthGO:004001440.028
response to chemicalGO:00422213200.028
Mouse
organelle fusionGO:004828430.028
protein localization to nucleusGO:003450430.028
endosomal transportGO:001619720.027
meiotic nuclear divisionGO:000712640.027
golgi vesicle transportGO:004819330.027
nuclear transportGO:005116940.027
positive regulation of catabolic processGO:000989640.027
response to drugGO:004249330.026
membrane fusionGO:006102520.026
nucleocytoplasmic transportGO:000691340.026
cellular amine metabolic processGO:004410620.026
modification dependent macromolecule catabolic processGO:004363230.026
Mouse
positive regulation of cellular catabolic processGO:003133130.025
protein importGO:001703830.025
regulation of establishment of protein localizationGO:007020140.025
cellular nitrogen compound metabolic processGO:00346412900.025
single organism metabolic processGO:00447102170.025
positive regulation of cell cycleGO:004578730.024
regulation of protein transportGO:005122330.024
nitrogen compound metabolic processGO:00068073190.024
rna metabolic processGO:00160702190.024
response to stressGO:00069502630.024
Mouse
single organism membrane fusionGO:004480120.024
nucleobase containing compound metabolic processGO:00061392740.024
gtp catabolic processGO:000618420.024
meiotic cell cycle processGO:190304630.023
regulation of metabolic processGO:00192223590.023
regulation of bindingGO:005109830.023
mitochondrion organizationGO:000700540.023
gene expressionGO:00104672520.023
cellular aromatic compound metabolic processGO:00067252950.023
regulation of cytokine productionGO:000181730.022
system processGO:00030081850.022
guanosine containing compound metabolic processGO:190106840.022
organic cyclic compound metabolic processGO:19013603010.022
regulation of cytoplasmic transportGO:190364940.022
positive regulation of cellular component biogenesisGO:004408930.022
cell surface receptor signaling pathwayGO:00071663250.022
proteasomal protein catabolic processGO:001049820.021
Mouse
gtp metabolic processGO:004603940.021
single organism nuclear importGO:190259330.021
cellular component disassemblyGO:002241110.021
regulation of cellular amine metabolic processGO:003323800.021
regulation of synaptic plasticityGO:004816710.021
establishment of localizationGO:00512342440.021
response to topologically incorrect proteinGO:003596620.021
Mouse
negative regulation of protein phosphorylationGO:000193340.021
macromolecule biosynthetic processGO:00090592270.021
rna localizationGO:000640340.021
nucleic acid metabolic processGO:00903042440.021
organic substance biosynthetic processGO:19015762890.021
stem cell maintenanceGO:001982740.021
regulation of protein catabolic processGO:004217610.021
regulation of intracellular protein transportGO:003315730.021
cytokinesisGO:000091030.021
adult behaviorGO:003053420.021
extrinsic apoptotic signaling pathwayGO:009719130.021
cellular biosynthetic processGO:00442492860.021
cognitionGO:005089010.020
regulation of protein modification by small protein conjugation or removalGO:190332030.020
cellular macromolecule metabolic processGO:00442603910.020
Human Mouse
cellular response to external stimulusGO:007149620.020
protein metabolic processGO:00195381830.020
Human Mouse
regulation of nitrogen compound metabolic processGO:00511712510.020
regulation of cell shapeGO:000836010.020
protein polymerizationGO:005125840.020
organelle organizationGO:00069962270.020
guanosine containing compound catabolic processGO:190106920.020
nuclear importGO:005117030.020
organonitrogen compound metabolic processGO:1901564740.020
regulation of biological qualityGO:00650082630.020
regulation of circadian rhythmGO:004275240.020
transcription dna templatedGO:00063511810.020
negative regulation of cellular processGO:00485232830.020
single organism transportGO:00447652060.020
regulation of protein targetingGO:190353320.019
membrane invaginationGO:001032410.019
g1 s transition of mitotic cell cycleGO:000008210.019
protein targeting to nucleusGO:004474430.019
stem cell proliferationGO:007208940.019
embryonic organ developmentGO:00485683810.019
hemopoiesisGO:00300971830.019
negative regulation of biological processGO:00485193040.019
regulation of signalingGO:00230512350.019
cellular nitrogen compound biosynthetic processGO:00442712180.019
regulation of protein ubiquitinationGO:003139630.019
heterocycle metabolic processGO:00464832900.019
cellular response to biotic stimulusGO:007121630.019
regulation of protein localization to nucleusGO:190018020.019
single organism organelle organizationGO:19025891990.019
regulation of nucleocytoplasmic transportGO:004682220.019
regulation of gene expressionGO:00104682650.019
immune system processGO:00023762410.018
regulation of macromolecule metabolic processGO:00602553170.018
carboxylic acid metabolic processGO:0019752220.018
cell migrationGO:00164772370.018
regulation of cellular amino acid metabolic processGO:000652100.018
vasculature developmentGO:00019442780.018
synaptic growth at neuromuscular junctionGO:005112420.018
aromatic compound biosynthetic processGO:00194382170.018
regulation of synapse organizationGO:005080730.018
cellular response to extracellular stimulusGO:003166820.018
actin polymerization or depolymerizationGO:000815420.018
regulation of cell activationGO:005086510.018
regulation of mrna processingGO:005068430.018
response to external stimulusGO:00096052640.018
heterocycle biosynthetic processGO:00181302150.018
regulation of cell communicationGO:00106462320.018
organic cyclic compound biosynthetic processGO:19013622230.018
cellular ketone metabolic processGO:0042180110.018
nucleobase containing compound biosynthetic processGO:00346542050.018
nucleic acid templated transcriptionGO:00976591810.018
transportGO:00068102200.018
phagocytosis engulfmentGO:000691110.018
establishment of protein localization to plasma membraneGO:009000210.018
compound eye developmentGO:004874920.018
protein complex disassemblyGO:004324110.018
synaptic vesicle localizationGO:009747910.018
cellular component movementGO:00069283350.018
exocytosisGO:000688710.018
regulation of cellular biosynthetic processGO:00313262450.018
rna biosynthetic processGO:00327741810.017
chemosensory behaviorGO:000763510.017
synaptic vesicle transportGO:004848910.017
protein acetylationGO:000647320.017
ribonucleoside monophosphate catabolic processGO:000915840.017
response to uvGO:000941130.017
regulation of biosynthetic processGO:00098892500.017
oxoacid metabolic processGO:0043436310.017
neuroblast proliferationGO:000740520.017
positive regulation of secretion by cellGO:190353210.017
regulation of meiotic cell cycleGO:005144510.017
cellular amino acid metabolic processGO:000652070.017
mitotic dna integrity checkpointGO:004477440.017
regulation of cellular ketone metabolic processGO:001056570.017
biosynthetic processGO:00090582940.017
cell cycle g1 s phase transitionGO:004484310.017
central nervous system developmentGO:00074173870.017
stem cell divisionGO:001714510.017
cellular response to nutrient levelsGO:003166920.017
regulation of synapse assemblyGO:005196330.017
cellular macromolecule biosynthetic processGO:00346452240.017
regulation of reproductive processGO:200024140.017
macromolecular complex disassemblyGO:003298410.017
brain developmentGO:00074202930.017
regulation of protein import into nucleusGO:004230620.017
cellular component assemblyGO:00226071700.017
cellular response to chemical stimulusGO:00708871570.017
Mouse
spermatid developmentGO:000728620.016
small molecule metabolic processGO:0044281770.016
organic acid metabolic processGO:0006082310.016
cellular respirationGO:004533330.016
protein secretionGO:000930610.016
locomotionGO:00400113130.016
regulation of cellular metabolic processGO:00313233200.016
regulation of purine nucleotide catabolic processGO:003312120.016
hematopoietic or lymphoid organ developmentGO:00485341910.016
protein polyubiquitinationGO:000020940.016
Human
regulation of protein polymerizationGO:003227120.016
establishment of synaptic vesicle localizationGO:009748010.016
positive regulation of secretionGO:005104710.016
regulation of signal transductionGO:00099662250.016
sensory organ developmentGO:00074233930.016
actin filament polymerizationGO:003004120.016
protein import into nucleusGO:000660630.016
embryonic organ morphogenesisGO:00485622740.016
regulation of rna biosynthetic processGO:20011412130.016
regulation of response to stimulusGO:00485832690.016
cellular carbohydrate metabolic processGO:004426240.016
cellular component biogenesisGO:00440851780.015
eye developmentGO:00016542770.015
regulation of primary metabolic processGO:00800903110.015
protein dephosphorylationGO:000647030.015
peptidyl serine phosphorylationGO:001810510.015
cellular response to radiationGO:007147840.015
positive regulation of cell activationGO:005086710.015
regulation of multicellular organismal processGO:00512392770.015
regulation of cell projection assemblyGO:006049140.015
negative regulation of protein kinase activityGO:000646940.015
purine ribonucleoside monophosphate catabolic processGO:000916940.015
regulation of nucleotide catabolic processGO:003081120.015
single fertilizationGO:000733830.015
cellular component morphogenesisGO:00329893360.015
atp catabolic processGO:000620040.015
cellular response to lipopolysaccharideGO:007122230.015
cellular response to topologically incorrect proteinGO:003596720.015
Mouse
spermatid differentiationGO:004851520.015
mitotic cell cycle embryonicGO:004544820.015
blood vessel developmentGO:00015682460.015
head developmentGO:00603223030.015
peptide transportGO:001583310.015
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
morphogenesis of an epitheliumGO:00020093330.015
nucleoside monophosphate catabolic processGO:000912540.015
regulation of nucleic acid templated transcriptionGO:19035062130.015
negative regulation of kinase activityGO:003367340.015
cell projection organizationGO:00300302840.015
alcohol biosynthetic processGO:004616520.015
immune system developmentGO:00025201910.015
cellular response to starvationGO:000926710.015
mitotic g2 dna damage checkpointGO:000709530.015
peptidyl serine modificationGO:001820920.015
protein acylationGO:004354330.014
locomotor rhythmGO:004547530.014
positive regulation of cytokine productionGO:000181920.014
tissue remodelingGO:004877140.014
protein stabilizationGO:005082120.014
muscle structure developmentGO:00610611960.014
cytoskeleton dependent cytokinesisGO:006164030.014
cell part morphogenesisGO:00329902460.014
regulation of i kappab kinase nf kappab signalingGO:004312240.014
sequestering of metal ionGO:005123830.014
peptidyl lysine acetylationGO:001839420.014
localization of cellGO:00516742440.014
homeostatic processGO:00425921420.014
regulation of transcription dna templatedGO:00063552130.014
post golgi vesicle mediated transportGO:000689210.014
symbiosis encompassing mutualism through parasitismGO:004440340.014
cell motilityGO:00488702440.014
positive regulation of cellular amine metabolic processGO:003324000.014
internal protein amino acid acetylationGO:000647520.014
positive regulation of cytosolic calcium ion concentrationGO:000720440.014
mitotic dna damage checkpointGO:004477340.014
sequestering of calcium ionGO:005120830.014
startle responseGO:000196440.014
digestive system developmentGO:00551232890.014
regulation of rna metabolic processGO:00512522240.014
vacuolar transportGO:000703420.014
regulation of peptidyl tyrosine phosphorylationGO:005073010.014
positive regulation of biological processGO:00485182530.014
regulation of protein bindingGO:004339330.014
digestive tract morphogenesisGO:00485462310.014
secondary metabolic processGO:001974830.014
internal peptidyl lysine acetylationGO:001839320.014
response to alkaloidGO:004327920.013
centrosome organizationGO:005129710.013
heart developmentGO:00075073130.013
regulation of metal ion transportGO:001095940.013
positive regulation of nucleoside metabolic processGO:004597910.013
cellular amide metabolic processGO:004360340.013
regulation of macromolecule biosynthetic processGO:00105562250.013
fertilizationGO:000956630.013
meiotic chromosome segregationGO:004513230.013
regulation of extrinsic apoptotic signaling pathwayGO:200123630.013
neuron differentiationGO:00301823530.013
neurotransmitter transportGO:000683620.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
cellular protein metabolic processGO:00442671290.013
Human Mouse
macromolecule modificationGO:00434121110.013
Human Mouse
purine nucleoside monophosphate catabolic processGO:000912840.013
negative regulation of protein complex assemblyGO:003133310.013
regulation of nucleoside metabolic processGO:000911820.013
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
regulation of jak stat cascadeGO:004642530.013
regulation of cellular macromolecule biosynthetic processGO:20001122220.013
i kappab kinase nf kappab signalingGO:000724940.013
cell morphogenesisGO:00009022890.013
regulation of carbohydrate metabolic processGO:000610940.013
cell matrix adhesionGO:000716040.013
leukocyte proliferationGO:007066110.013
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.013
response to carbohydrateGO:000974330.013
erk1 and erk2 cascadeGO:007037140.013
germ line stem cell maintenanceGO:003071820.012
cell substrate adhesionGO:003158940.012
sensory perception of painGO:001923310.012
developmental growthGO:00485891660.012
positive regulation of cell adhesionGO:004578510.012
camera type eye developmentGO:00430102220.012
tube morphogenesisGO:00352393490.012
regulation of sequestering of calcium ionGO:005128240.012
primary neural tube formationGO:001402010.012
neurotransmitter secretionGO:000726920.012
cellular protein modification processGO:00064641000.012
Human Mouse
cellular localizationGO:0051641970.012
response to unfolded proteinGO:000698620.012
cytoplasm organizationGO:000702840.012
regulation of developmental processGO:00507932470.012
development of primary female sexual characteristicsGO:004654540.012
regulation of neural precursor cell proliferationGO:200017730.012
intracellular signal transductionGO:0035556850.012
positive regulation of apoptotic signaling pathwayGO:200123510.012
response to organic substanceGO:00100331530.012
Mouse
organelle assemblyGO:00709251100.012
embryo development ending in birth or egg hatchingGO:00097922710.012
regulation of cellular protein catabolic processGO:190336210.012
generation of neuronsGO:00486993850.012
positive regulation of cellular processGO:00485222010.012
negative regulation of sequestering of calcium ionGO:005128340.012
regulation of multicellular organismal developmentGO:20000262230.012
positive regulation of gtp catabolic processGO:003312610.012
regulation of nucleobase containing compound metabolic processGO:00192192500.012
regulation of gtp catabolic processGO:003312420.012
lateral inhibitionGO:004633110.012
regulation of erk1 and erk2 cascadeGO:007037240.012
regulation of inflammatory responseGO:005072720.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
nucleic acid transportGO:005065720.012
regulation of gtpase activityGO:004308720.012
negative regulation of synapse assemblyGO:005196420.012
neurological system processGO:0050877620.012
multi organism processGO:00517041340.012
positive regulation of cytoskeleton organizationGO:005149530.012
positive regulation of map kinase activityGO:004340630.012
cellular response to molecule of bacterial originGO:007121930.012
positive regulation of purine nucleotide catabolic processGO:003312310.012
gastrulationGO:00073692080.012
positive regulation of dna metabolic processGO:005105410.012
response to external biotic stimulusGO:0043207970.012
positive regulation of nucleotide catabolic processGO:003081310.011
er nucleus signaling pathwayGO:000698420.011
protein homooligomerizationGO:005126030.011
production of molecular mediator of immune responseGO:000244020.011
post embryonic organ developmentGO:004856940.011
neuron developmentGO:00486662620.011
microtubule organizing center organizationGO:003102310.011
negative regulation of cytokine productionGO:000181810.011
response to monosaccharideGO:003428430.011
regulation of autophagyGO:001050630.011
negative regulation of catabolic processGO:000989530.011
digestive tract developmentGO:00485652650.011
antimicrobial humoral responseGO:001973020.011
mitochondrial transportGO:000683920.011
protein modification processGO:00362111000.011
Human Mouse
interspecies interaction between organismsGO:004441940.011
angiogenesisGO:00015251580.011
regulation of protein complex disassemblyGO:004324410.011
catecholamine metabolic processGO:000658420.011
cell projection morphogenesisGO:00488582440.011
positive regulation of gtpase activityGO:004354710.011
b cell activationGO:004211320.011
nucleobase containing compound transportGO:001593120.011
macroautophagyGO:001623610.011
regulation of protein localization to plasma membraneGO:190307610.011
mononuclear cell proliferationGO:003294310.011
small molecule catabolic processGO:004428230.011
muscle cell differentiationGO:00426921390.011
regulation of mrna splicing via spliceosomeGO:004802430.011
response to hydrogen peroxideGO:004254230.011
pole plasm assemblyGO:000731540.011
regulation of dna templated transcription elongationGO:003278430.011
regulation of dendrite developmentGO:005077330.011
dna templated transcription elongationGO:000635430.011
carbohydrate homeostasisGO:003350010.011
neuron neuron synaptic transmissionGO:000727010.011
regulation of organ growthGO:004662030.011
regulation of transporter activityGO:003240920.011
phosphate containing compound metabolic processGO:00067961080.011
transcription from rna polymerase ii promoterGO:0006366800.011
nuclear exportGO:005116810.011
sensory organ morphogenesisGO:00905962000.011
growthGO:00400071740.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
signal transduction in absence of ligandGO:003803410.011
regulation of localizationGO:00328791040.011
blood vessel morphogenesisGO:00485142160.011
cellular response to light stimulusGO:007148240.011
regulation of blood pressureGO:000821710.011
cellular response to unfolded proteinGO:003462020.011
phosphorus metabolic processGO:00067931090.011
response to nutrientGO:000758430.011
somatic muscle developmentGO:000752540.011
endoplasmic reticulum unfolded protein responseGO:003096820.011
spindle assemblyGO:005122520.010
lamellipodium assemblyGO:003003210.010
negative regulation of mapk cascadeGO:004340940.010
chordate embryonic developmentGO:00430092710.010
regulation of stem cell proliferationGO:007209120.010
regulation of wound healingGO:006104120.010
negative regulation of protein transportGO:005122430.010
cortical actin cytoskeleton organizationGO:003086610.010
regulation of alternative mrna splicing via spliceosomeGO:000038110.010
negative regulation of multi organism processGO:004390130.010
specification of symmetryGO:00097992040.010
sleepGO:003043110.010
carbohydrate biosynthetic processGO:001605110.010
regulation of exocytosisGO:001715710.010
cytosolic calcium ion transportGO:006040130.010
cellular component assembly involved in morphogenesisGO:00109271070.010
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.010
ear developmentGO:00435831270.010
regulation of programmed cell deathGO:00430671010.010
cortical cytoskeleton organizationGO:003086510.010
positive regulation of small gtpase mediated signal transductionGO:005105710.010
lymphocyte proliferationGO:004665110.010
calcium ion transport into cytosolGO:006040230.010
regionalizationGO:00030022740.010
negative regulation of cellular catabolic processGO:003133030.010
positive regulation of i kappab kinase nf kappab signalingGO:004312330.010
establishment of rna localizationGO:005123630.010
female meiotic divisionGO:000714320.010
muscle cell developmentGO:00550011150.010
positive regulation of protein complex assemblyGO:003133420.010
female gonad developmentGO:000858540.010

ube2w disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.043
nervous system diseaseDOID:86300.027
disease of metabolismDOID:001466700.014
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
organ system cancerDOID:005068600.014
inherited metabolic disorderDOID:65500.012
musculoskeletal system diseaseDOID:1700.011
sensory system diseaseDOID:005015500.011
eye diseaseDOID:561400.010
eye and adnexa diseaseDOID:149200.010