Danio rerio

53 known processes

dlat

dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)

(Aliases: wu:fc86g11,wu:fj57d06,wu:fc21f08,wu:fc14f10)

dlat biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of metabolic processGO:00192223590.742
larval developmentGO:000216420.698
cellular component movementGO:00069283350.601
multi organism processGO:00517041340.547
biosynthetic processGO:00090582940.517
protein targeting to nucleusGO:004474430.489
regulation of multicellular organismal processGO:00512392770.489
regulation of multicellular organismal developmentGO:20000262230.439
regulation of nucleocytoplasmic transportGO:004682220.436
cell migrationGO:00164772370.419
signal transductionGO:00071654550.417
locomotionGO:00400113130.412
agingGO:000756820.390
regulation of macromolecule metabolic processGO:00602553170.384
cell motilityGO:00488702440.372
central nervous system developmentGO:00074173870.369
multicellular organism growthGO:003526440.369
regulation of gene expressionGO:00104682650.365
acetyl coa metabolic processGO:000608410.351
reproductionGO:0000003400.349
Worm
localization of cellGO:00516742440.346
nuclear transportGO:005116940.346
developmental process involved in reproductionGO:0003006270.335
meiotic nuclear divisionGO:000712640.333
regulation of meiotic cell cycleGO:005144510.326
embryo development ending in birth or egg hatchingGO:00097922710.322
Worm
negative regulation of biological processGO:00485193040.320
cellular process involved in reproduction in multicellular organismGO:0022412280.316
single organism localizationGO:19025782250.312
protein import into nucleusGO:000660630.300
protein importGO:001703830.298
protein localization to nucleusGO:003450430.296
coenzyme biosynthetic processGO:000910820.285
multicellular organism reproductionGO:0032504350.279
gamete generationGO:0007276330.270
regulation of intracellular protein transportGO:003315730.249
cell projection organizationGO:00300302840.246
single organism nuclear importGO:190259330.240
regulation of protein targetingGO:190353320.239
generation of neuronsGO:00486993850.234
pole plasm assemblyGO:000731540.233
cellular respirationGO:004533330.233
regulation of establishment of protein localizationGO:007020140.231
establishment of localizationGO:00512342440.226
Worm
growthGO:00400071740.222
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.217
transmembrane transportGO:00550851200.210
germ cell developmentGO:0007281220.207
peptidyl serine modificationGO:001820920.205
regulation of developmental processGO:00507932470.205
single organism transportGO:00447652060.199
nuclear importGO:005117030.198
regulation of cellular metabolic processGO:00313233200.194
establishment of protein localization to organelleGO:007259440.194
cellular component biogenesisGO:00440851780.192
cellular biosynthetic processGO:00442492860.192
positive regulation of cellular processGO:00485222010.192
phosphorus metabolic processGO:00067931090.191
oogenesisGO:0048477140.187
regulation of protein transportGO:005122330.187
regulation of cell differentiationGO:00455951420.185
regulation of synaptic growth at neuromuscular junctionGO:000858210.182
heart developmentGO:00075073130.181
regulation of dna replicationGO:000627530.181
actin polymerization or depolymerizationGO:000815420.179
positive regulation of biological processGO:00485182530.178
nucleocytoplasmic transportGO:000691340.178
developmental growthGO:00485891660.177
cellular nitrogen compound metabolic processGO:00346412900.175
transportGO:00068102200.174
Worm
pyruvate metabolic processGO:000609010.172
single organism reproductive processGO:0044702400.171
regulation of protein import into nucleusGO:004230620.167
spermatid developmentGO:000728620.163
cell morphogenesisGO:00009022890.161
positive regulation of metabolic processGO:00098931080.159
positive regulation of cellular component biogenesisGO:004408930.158
sexual reproductionGO:0019953360.157
fertilizationGO:000956630.156
adherens junction organizationGO:003433240.155
intracellular transportGO:0046907320.155
negative regulation of response to stimulusGO:00485851040.155
cell substrate adhesionGO:003158940.155
establishment of localization in cellGO:0051649770.155
positive regulation of cell cycleGO:004578730.154
positive regulation of gene expressionGO:0010628710.152
positive regulation of transportGO:005105020.150
protein complex localizationGO:003150310.149
regulation of cellular protein metabolic processGO:0032268520.146
blood vessel morphogenesisGO:00485142160.145
neuron differentiationGO:00301823530.143
regulation of cytoplasmic transportGO:190364940.143
peptidyl serine phosphorylationGO:001810510.142
striated muscle cell differentiationGO:00511461290.138
regulation of primary metabolic processGO:00800903110.138
response to chemicalGO:00422213200.137
regulation of response to stimulusGO:00485832690.136
macromolecule biosynthetic processGO:00090592270.136
system processGO:00030081850.135
regulation of synapse organizationGO:005080730.135
lamellipodium organizationGO:009758110.135
synaptic growth at neuromuscular junctionGO:005112420.134
muscle cell differentiationGO:00426921390.134
actin filament polymerizationGO:003004120.133
muscle tissue developmentGO:00605371100.131
regulation of cell projection assemblyGO:006049140.131
nitrogen compound metabolic processGO:00068073190.131
regulation of epithelial cell proliferationGO:005067830.131
regulation of synapse assemblyGO:005196330.130
cell proliferationGO:0008283800.129
skeletal system developmentGO:00015011810.125
regulation of cell developmentGO:00602841000.125
blood vessel developmentGO:00015682460.125
regulation of reproductive processGO:200024140.125
nitrogen compound transportGO:0071705230.124
cellular component assembly involved in morphogenesisGO:00109271070.122
negative regulation of protein complex assemblyGO:003133310.121
cellular component assemblyGO:00226071700.120
positive regulation of nitrogen compound metabolic processGO:0051173690.119
digestive tract developmentGO:00485652650.116
cellular localizationGO:0051641970.115
actin filament based processGO:0030029640.113
regulation of nitrogen compound metabolic processGO:00511712510.113
regulation of signalingGO:00230512350.113
sensory system developmentGO:0048880760.113
negative regulation of protein phosphorylationGO:000193340.112
regulation of anatomical structure morphogenesisGO:00226031300.112
lateral inhibitionGO:004633110.109
cellular amine metabolic processGO:004410620.107
regulation of protein polymerizationGO:003227120.107
ameboidal type cell migrationGO:00016671430.106
negative regulation of protein import into nucleusGO:004230820.106
vasculature developmentGO:00019442780.106
keratinocyte differentiationGO:003021600.105
spermatid differentiationGO:004851520.103
lamellipodium assemblyGO:003003210.103
negative regulation of cytoplasmic transportGO:190365020.103
purine nucleoside monophosphate catabolic processGO:000912840.100
organic substance biosynthetic processGO:19015762890.100
striated muscle cell developmentGO:00550021080.099
positive regulation of developmental processGO:0051094500.099
single organism metabolic processGO:00447102170.098
intracellular signal transductionGO:0035556850.097
response to external stimulusGO:00096052640.097
small molecule metabolic processGO:0044281770.096
stem cell proliferationGO:007208940.096
negative regulation of mapk cascadeGO:004340940.096
regulation of gene expression epigeneticGO:0040029110.096
response to abiotic stimulusGO:00096281220.095
digestive tract morphogenesisGO:00485462310.095
multi organism reproductive processGO:0044703360.090
wnt signaling pathwayGO:0016055800.090
cellular macromolecule metabolic processGO:00442603910.090
positive regulation of translationGO:004572710.090
meiotic cell cycle processGO:190304630.087
peptide transportGO:001583310.087
nucleobase containing compound biosynthetic processGO:00346542050.087
single fertilizationGO:000733830.087
ion transportGO:00068111140.087
synaptic transmissionGO:0007268350.087
regulation of nucleobase containing compound metabolic processGO:00192192500.086
striated muscle tissue developmentGO:00147061100.086
response to uvGO:000941130.084
reproductive processGO:0022414400.084
morphogenesis of an epitheliumGO:00020093330.083
regulation of intracellular signal transductionGO:1902531570.083
female gamete generationGO:0007292140.083
regulation of neurogenesisGO:0050767870.083
organelle assemblyGO:00709251100.083
cardiac muscle tissue developmentGO:0048738480.083
maternal determination of anterior posterior axis embryoGO:000835840.082
cellular macromolecule biosynthetic processGO:00346452240.081
regulation of protein localization to nucleusGO:190018020.081
actin cytoskeleton organizationGO:0030036630.081
cell cell signalingGO:0007267520.080
carbohydrate derivative biosynthetic processGO:1901137430.079
neuroblast proliferationGO:000740520.078
programmed cell deathGO:00125011190.078
regulation of cellular biosynthetic processGO:00313262450.078
rna metabolic processGO:00160702190.078
brain developmentGO:00074202930.078
phosphate containing compound metabolic processGO:00067961080.077
cofactor biosynthetic processGO:0051188100.077
cortical cytoskeleton organizationGO:003086510.077
embryonic organ developmentGO:00485683810.077
positive regulation of macromolecule metabolic processGO:0010604930.076
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.076
head developmentGO:00603223030.076
cytoplasm organizationGO:000702840.075
negative regulation of jnk cascadeGO:004632910.075
organic cyclic compound metabolic processGO:19013603010.075
aromatic compound biosynthetic processGO:00194382170.074
regulation of response to cytokine stimulusGO:006075930.074
regulation of mrna processingGO:005068430.073
positive regulation of cellular amino acid metabolic processGO:004576400.073
negative regulation of cellular processGO:00485232830.073
neuron projection developmentGO:00311751800.072
regulation of cellular amine metabolic processGO:003323800.072
epidermal cell differentiationGO:0009913360.072
acyl coa biosynthetic processGO:007161610.072
amine metabolic processGO:000930820.071
muscle cell developmentGO:00550011150.071
axon developmentGO:00615641660.071
regulation of nervous system developmentGO:0051960900.070
organelle organizationGO:00069962270.070
regulation of signal transductionGO:00099662250.070
skeletal muscle fiber developmentGO:0048741350.070
regulation of biological qualityGO:00650082630.069
chordate embryonic developmentGO:00430092710.068
negative regulation of metabolic processGO:0009892860.067
positive regulation of cellular catabolic processGO:003133130.067
organelle localizationGO:0051640490.067
regulation of localizationGO:00328791040.067
ribonucleoside monophosphate catabolic processGO:000915840.067
negative regulation of protein transportGO:005122430.066
regulation of filopodium assemblyGO:005148920.066
positive regulation of muscle cell differentiationGO:005114910.066
protein localizationGO:0008104400.066
oocyte anterior posterior axis specificationGO:000731440.066
organic acid metabolic processGO:0006082310.065
regulation of multicellular organism growthGO:004001440.065
oocyte maturationGO:000155640.065
cytoskeleton organizationGO:0007010960.065
p38mapk cascadeGO:003806610.065
neuron developmentGO:00486662620.065
forebrain developmentGO:0030900960.064
protein complex disassemblyGO:004324110.064
pronuclear migrationGO:003504610.064
multicellular organismal reproductive processGO:0048609350.063
i kappab kinase nf kappab signalingGO:000724940.062
regulation of cell projection organizationGO:0031344440.062
negative regulation of cell communicationGO:0010648960.062
nucleoside monophosphate catabolic processGO:000912540.062
organonitrogen compound metabolic processGO:1901564740.061
single organism cellular localizationGO:1902580460.061
regulation of oocyte developmentGO:006028130.061
positive regulation of catabolic processGO:000989640.060
peptidyl threonine phosphorylationGO:001810710.060
regulation of cellular ketone metabolic processGO:001056570.059
cell part morphogenesisGO:00329902460.059
cellular nitrogen compound biosynthetic processGO:00442712180.059
gtp metabolic processGO:004603940.058
guanosine containing compound metabolic processGO:190106840.058
regulation of bindingGO:005109830.058
cellular aromatic compound metabolic processGO:00067252950.057
nucleobase containing compound metabolic processGO:00061392740.057
regulation of nucleoside metabolic processGO:000911820.057
forebrain cell migrationGO:002188510.057
stem cell maintenanceGO:001982740.057
phosphorylationGO:0016310690.056
tube morphogenesisGO:00352393490.056
negative regulation of gene expressionGO:0010629650.055
regulation of cellular component organizationGO:0051128860.055
macromolecular complex disassemblyGO:003298410.054
nucleic acid metabolic processGO:00903042440.054
regulation of cell substrate adhesionGO:001081010.053
chemical homeostasisGO:0048878490.053
actomyosin structure organizationGO:0031032530.052
carbohydrate derivative metabolic processGO:1901135610.052
sleepGO:003043110.052
regulation of rna metabolic processGO:00512522240.052
cell cycleGO:0007049930.051
behaviorGO:0007610740.051
purine ribonucleotide metabolic processGO:0009150270.051
nuclear divisionGO:0000280230.051
positive regulation of nucleic acid templated transcriptionGO:1903508570.050
regulation of molecular functionGO:0065009700.050
protein polymerizationGO:005125840.050
axis specificationGO:0009798430.050
cellular response to organic substanceGO:00713101050.050
dna metabolic processGO:0006259270.049
cellular component disassemblyGO:002241110.049
organic substance transportGO:0071702580.049
regulation of stem cell differentiationGO:200073640.049
regulation of purine nucleotide catabolic processGO:003312120.049
regulation of synaptic plasticityGO:004816710.048
guanosine containing compound catabolic processGO:190106920.048
macromolecular complex subunit organizationGO:0043933740.048
positive regulation of small gtpase mediated signal transductionGO:005105710.048
regulation of rna biosynthetic processGO:20011412130.047
cell projection morphogenesisGO:00488582440.047
negative regulation of protein kinase activityGO:000646940.047
gtp catabolic processGO:000618420.047
response to organic substanceGO:00100331530.047
cell deathGO:00082191210.047
mitotic cell cycleGO:0000278640.046
response to biotic stimulusGO:0009607970.046
rna localizationGO:000640340.046
sensory organ developmentGO:00074233930.046
response to stressGO:00069502630.046
camera type eye developmentGO:00430102220.045
regulation of protein complex assemblyGO:004325430.045
epithelial cell developmentGO:0002064420.045
intracellular mrna localizationGO:000829810.044
positive regulation of cellular amine metabolic processGO:003324000.044
cardiac conduction system developmentGO:000316110.044
positive regulation of dna metabolic processGO:005105410.044
cellular protein complex assemblyGO:0043623190.044
nitric oxide metabolic processGO:004620920.044
epithelial cell morphogenesisGO:000338220.044
embryonic heart tube developmentGO:00350501330.044
sprouting angiogenesisGO:0002040530.044
negative regulation of signalingGO:0023057960.044
negative regulation of phosphate metabolic processGO:0045936130.044
regulation of protein depolymerizationGO:190187910.044
skeletal muscle tissue developmentGO:0007519670.043
regulation of chromosome segregationGO:005198310.043
heterocycle metabolic processGO:00464832900.043
regulation of cell shapeGO:000836010.043
immune system processGO:00023762410.043
regulation of protein modification by small protein conjugation or removalGO:190332030.043
centrosome organizationGO:005129710.042
small gtpase mediated signal transductionGO:000726480.042
single organism biosynthetic processGO:0044711710.042
cognitionGO:005089010.042
gastrulationGO:00073692080.042
chemotaxisGO:00069351040.042
connective tissue developmentGO:0061448990.041
regulation of circadian rhythmGO:004275240.041
cellular response to stressGO:0033554620.041
ubiquitin dependent protein catabolic processGO:000651130.041
deathGO:00162651210.041
cellular protein metabolic processGO:00442671290.040
protein localization to plasma membraneGO:007265910.040
negative regulation of protein localization to nucleusGO:190018120.040
regulation of protein bindingGO:004339330.040
microtubule organizing center organizationGO:003102310.040
response to other organismGO:0051707970.040
regulation of neural precursor cell proliferationGO:200017730.040
cellular amino acid metabolic processGO:000652070.040
cellular ketone metabolic processGO:0042180110.040
protein modification processGO:00362111000.040
regulation of cell communicationGO:00106462320.040
negative regulation of signal transductionGO:0009968940.039
macromolecular complex assemblyGO:0065003350.039
negative regulation of intracellular protein transportGO:009031730.039
actin filament based movementGO:003004810.039
regulation of phosphorus metabolic processGO:0051174430.039
protein metabolic processGO:00195381830.039
sensory perception of touchGO:005097520.039
positive regulation of biosynthetic processGO:0009891680.039
nucleic acid templated transcriptionGO:00976591810.039
locomotor rhythmGO:004547530.038
regulation of catalytic activityGO:0050790550.038
single organism intracellular transportGO:1902582250.038
regulation of cellular amino acid metabolic processGO:000652100.038
negative regulation of protein serine threonine kinase activityGO:007190120.038
cardiac muscle fiber developmentGO:004873930.038
regulation of macromolecule biosynthetic processGO:00105562250.038
regulation of nucleotide catabolic processGO:003081120.038
digestive system developmentGO:00551232890.038
peptidyl threonine modificationGO:001821010.038
skeletal muscle thin filament assemblyGO:003024040.037
single organism organelle organizationGO:19025891990.037
skeletal system morphogenesisGO:00487051020.037
negative regulation of nucleocytoplasmic transportGO:004682320.037
negative regulation of intracellular signal transductionGO:1902532220.037
regulation of circadian sleep wake cycleGO:004274910.037
apoptotic processGO:00069151160.037
cell surface receptor signaling pathwayGO:00071663250.037
myotube differentiationGO:0014902450.037
regulation of dna templated transcription in response to stressGO:004362000.037
gene expressionGO:00104672520.037
cell projection assemblyGO:0030031640.036
regulation of growthGO:0040008420.036
muscle fiber developmentGO:0048747520.036
ras protein signal transductionGO:000726570.036
embryonic organ morphogenesisGO:00485622740.036
positive regulation of striated muscle tissue developmentGO:004584410.035
negative regulation of intracellular transportGO:003238730.035
regulation of circadian sleep wake cycle sleepGO:004518710.035
mesoderm morphogenesisGO:0048332510.035
response to mercury ionGO:004668910.035
response to endogenous stimulusGO:0009719830.034
response to light stimulusGO:0009416460.034
rna biosynthetic processGO:00327741810.034
centrosome cycleGO:000709810.034
regulation of mrna catabolic processGO:006101330.034
enzyme linked receptor protein signaling pathwayGO:00071671060.034
positive regulation of cellular metabolic processGO:0031325940.034
mesenchyme developmentGO:00604851270.034
positive regulation of nucleobase containing compound metabolic processGO:0045935690.034
oocyte developmentGO:0048599140.033
regulation of bone remodelingGO:004685020.033
epithelial cell differentiationGO:00308551160.033
cell cycle arrestGO:000705010.033
mesenchymal cell differentiationGO:0048762870.033
negative regulation of kinase activityGO:003367340.033
cation transportGO:0006812810.033
purine ribonucleoside monophosphate catabolic processGO:000916940.033
positive regulation of multicellular organismal processGO:0051240520.033
regulation of dna metabolic processGO:0051052110.033
cell morphogenesis involved in neuron differentiationGO:00486671630.032
regulation of developmental growthGO:0048638380.032
regulation of peptidyl tyrosine phosphorylationGO:005073010.032
rhythmic processGO:0048511210.032
embryonic skeletal system developmentGO:0048706970.032
ear developmentGO:00435831270.032
organelle fissionGO:0048285230.032
organic cyclic compound biosynthetic processGO:19013622230.032
axon guidanceGO:0007411860.032
positive regulation of cell substrate adhesionGO:001081110.032
sulfur compound biosynthetic processGO:004427290.032
regulation of nucleic acid templated transcriptionGO:19035062130.032
heart morphogenesisGO:00030071560.032
positive regulation of i kappab kinase nf kappab signalingGO:004312330.031
sarcomerogenesisGO:004876940.031
regulation of transportGO:0051049450.031
adherens junction assemblyGO:003433310.031
rho protein signal transductionGO:000726650.031
regulation of alternative mrna splicing via spliceosomeGO:000038110.031
neuron projection morphogenesisGO:00488121610.031
multicellular organismal signalingGO:0035637220.031
muscle structure developmentGO:00610611960.031
negative regulation of macromolecule metabolic processGO:0010605760.031
transcription from rna polymerase ii promoterGO:0006366800.031
negative regulation of epithelial cell proliferationGO:005068010.030
positive regulation of cell divisionGO:005178120.030
regulation of axonogenesisGO:0050770320.030
phagocytosisGO:000690930.030
embryonic heart tube morphogenesisGO:00031431080.030
embryonic pattern specificationGO:0009880440.030
cellular response to hypoxiaGO:007145610.030
somatic muscle developmentGO:000752540.030
endoderm developmentGO:0007492490.030
cell junction maintenanceGO:003433120.030
eye developmentGO:00016542770.030
proteolysis involved in cellular protein catabolic processGO:005160330.030
regulation of biosynthetic processGO:00098892500.029
regulation of rho protein signal transductionGO:003502320.029
secondary metabolic processGO:001974830.029
mitochondrion organizationGO:000700540.029
regulation of receptor mediated endocytosisGO:004825940.029
monovalent inorganic cation transportGO:0015672420.029
nephron epithelium morphogenesisGO:007208810.029
cortical actin cytoskeleton organizationGO:003086610.029
cell morphogenesis involved in differentiationGO:00009041950.029
cellular response to external stimulusGO:007149620.029
germ line stem cell maintenanceGO:003071820.029
skin developmentGO:0043588540.029
acyl coa metabolic processGO:000663710.028
epithelial tube morphogenesisGO:00605621480.028
regulation of cell proliferationGO:0042127370.028
regulation of response to stressGO:0080134360.028
negative regulation of cellular metabolic processGO:0031324770.028
regulation of stem cell proliferationGO:007209120.028
homeostatic processGO:00425921420.028
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.028
establishment of organelle localizationGO:0051656450.028
response to cadmium ionGO:0046686140.028
angiogenesisGO:00015251580.028
protein complex assemblyGO:0006461300.028
erk1 and erk2 cascadeGO:007037140.028
cellular response to nutrient levelsGO:003166920.028
neuron projection guidanceGO:0097485860.027
segmentationGO:0035282970.027
regulation of cell deathGO:00109411030.027
regulation of cell morphogenesisGO:0022604420.027
regulation of myotube differentiationGO:001083020.027
respiratory electron transport chainGO:002290420.027
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.027
cellular macromolecular complex assemblyGO:0034622240.026
regulation of phosphorylationGO:0042325260.026
protein depolymerizationGO:005126110.026
adult behaviorGO:003053420.026
neural crest cell differentiationGO:0014033720.026
cardiac atrium developmentGO:000323040.026
entrainment of circadian clockGO:000964920.026
myofibril assemblyGO:0030239480.026
microtubule based movementGO:0007018330.026
heterocycle biosynthetic processGO:00181302150.026
calcium ion importGO:007050940.026
leukocyte proliferationGO:007066110.026
internal peptidyl lysine acetylationGO:001839320.026
cell matrix adhesionGO:000716040.026
negative regulation of gliogenesisGO:001401410.025
alternative mrna splicing via spliceosomeGO:000038010.025
atp catabolic processGO:000620040.025
pathway restricted smad protein phosphorylationGO:006038910.025
nitric oxide biosynthetic processGO:000680920.025
adherens junction maintenanceGO:003433420.025
exocytosisGO:000688710.025
neurological system processGO:0050877620.025
cellular macromolecule localizationGO:0070727210.025
negative regulation of i kappab kinase nf kappab signalingGO:004312410.025
mesoderm developmentGO:0007498880.025
regulation of protein ubiquitinationGO:003139630.025
positive regulation of cellular biosynthetic processGO:0031328680.025
stem cell differentiationGO:00488631170.024
negative regulation of cell differentiationGO:0045596460.024
actin filament organizationGO:0007015150.024

dlat disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.099
disease of metabolismDOID:001466700.047
inherited metabolic disorderDOID:65500.047
nervous system diseaseDOID:86300.029