Danio rerio

50 known processes

arrb2a

arrestin, beta 2a

(Aliases: zgc:66353,hm:zeh0294,wu:fc14e09,zeh0294,fc14e09)

arrb2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regionalizationGO:00030022740.100
chordate embryonic developmentGO:00430092710.078
biosynthetic processGO:00090582940.076
Human
single organism organelle organizationGO:19025891990.074
regulation of cellular macromolecule biosynthetic processGO:20001122220.065
Human
stem cell proliferationGO:007208940.065
regulation of rna biosynthetic processGO:20011412130.063
Human
macromolecule biosynthetic processGO:00090592270.063
Human
determination of bilateral symmetryGO:00098552040.062
cognitionGO:005089010.062
negative regulation of biological processGO:00485193040.061
Human Mouse Fly
organic substance biosynthetic processGO:19015762890.061
Human
regulation of metabolic processGO:00192223590.056
compound eye developmentGO:004874920.056
determination of left right symmetryGO:00073681790.056
cellular nitrogen compound metabolic processGO:00346412900.055
Human
sensory organ developmentGO:00074233930.051
regulation of primary metabolic processGO:00800903110.047
Human Mouse Fly
neuron differentiationGO:00301823530.047
negative regulation of cellular processGO:00485232830.046
Human Mouse Fly
cellular component biogenesisGO:00440851780.046
nucleobase containing compound metabolic processGO:00061392740.046
Human
cellular component movementGO:00069283350.045
regulation of biosynthetic processGO:00098892500.044
Human
system processGO:00030081850.044
Zebrafish
mesenchyme developmentGO:00604851270.043
nucleic acid templated transcriptionGO:00976591810.043
Human
synaptic growth at neuromuscular junctionGO:005112420.042
cell projection morphogenesisGO:00488582440.042
cilium morphogenesisGO:0060271850.042
positive regulation of stem cell proliferationGO:200064810.042
regulation of gene expressionGO:00104682650.041
Human Fly
heterocycle metabolic processGO:00464832900.041
Human
segmentationGO:0035282970.040
regulation of stem cell proliferationGO:007209120.040
digestive system developmentGO:00551232890.039
Fly
regulation of synapse organizationGO:005080730.039
transcription dna templatedGO:00063511810.039
Human
positive regulation of neural precursor cell proliferationGO:200017910.039
central nervous system developmentGO:00074173870.039
chemosensory behaviorGO:000763510.038
regulation of macromolecule metabolic processGO:00602553170.037
regulation of macromolecule biosynthetic processGO:00105562250.037
Human
heart developmentGO:00075073130.037
hemopoiesisGO:00300971830.036
Fly
regulation of nucleobase containing compound metabolic processGO:00192192500.036
Human
nucleic acid metabolic processGO:00903042440.036
Human
neurotransmitter secretionGO:000726920.035
ear developmentGO:00435831270.034
neuroblast proliferationGO:000740520.034
embryonic organ developmentGO:00485683810.034
skeletal system developmentGO:00015011810.033
cellular macromolecule biosynthetic processGO:00346452240.033
Human
signal transductionGO:00071654550.033
Human Zebrafish Mouse Fly
cell substrate adhesionGO:003158940.033
positive regulation of cell cycleGO:004578730.033
regulation of meiotic cell cycleGO:005144510.033
response to chemicalGO:00422213200.032
brain developmentGO:00074202930.032
specification of symmetryGO:00097992040.031
somite developmentGO:0061053960.031
muscle cell differentiationGO:00426921390.031
organelle organizationGO:00069962270.031
eye developmentGO:00016542770.031
cellular biosynthetic processGO:00442492860.031
Human
cellular component assembly involved in morphogenesisGO:00109271070.031
head developmentGO:00603223030.031
rna metabolic processGO:00160702190.031
Human
anterior posterior pattern specificationGO:00099521520.031
heart morphogenesisGO:00030071560.031
nitrogen compound metabolic processGO:00068073190.030
Human
cellular macromolecule metabolic processGO:00442603910.030
phagocytosisGO:000690930.030
regulation of synapse assemblyGO:005196330.030
stem cell divisionGO:001714510.029
embryonic organ morphogenesisGO:00485622740.029
stem cell maintenanceGO:001982740.028
rna biosynthetic processGO:00327741810.028
Human
blood vessel developmentGO:00015682460.028
protein metabolic processGO:00195381830.028
Human Mouse Fly
neurotransmitter transportGO:000683620.028
cell part morphogenesisGO:00329902460.028
larval developmentGO:000216420.027
Fly
regulation of synaptic growth at neuromuscular junctionGO:000858210.027
localization of cellGO:00516742440.027
cell surface receptor signaling pathwayGO:00071663250.027
Human Zebrafish Mouse Fly
camera type eye developmentGO:00430102220.027
epithelial cell differentiationGO:00308551160.027
vasculature developmentGO:00019442780.026
regulation of response to stimulusGO:00485832690.026
cellular response to organic substanceGO:00713101050.026
Human
cilium assemblyGO:0042384580.026
gene expressionGO:00104672520.025
Human Fly
hematopoietic or lymphoid organ developmentGO:00485341910.025
Fly
membrane invaginationGO:001032410.025
adult behaviorGO:003053420.025
Mouse
sleepGO:003043110.024
positive regulation of biological processGO:00485182530.024
Human Mouse Worm Fly
cellular protein catabolic processGO:004425740.024
Human
regulation of multicellular organismal developmentGO:20000262230.024
Fly
proteasomal protein catabolic processGO:001049820.024
Human
gastrulationGO:00073692080.024
Fly
regulation of nitrogen compound metabolic processGO:00511712510.024
Human
response to external stimulusGO:00096052640.024
regenerationGO:0031099910.024
regulation of cellular metabolic processGO:00313233200.024
cellular component assemblyGO:00226071700.024
cell projection organizationGO:00300302840.023
cilium organizationGO:0044782710.023
rostrocaudal neural tube patterningGO:0021903290.023
regulation of rna metabolic processGO:00512522240.023
Human
regulation of cellular ketone metabolic processGO:001056570.023
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.023
Human
regulation of biological qualityGO:00650082630.022
Fly
regulation of nervous system developmentGO:0051960900.022
heterocycle biosynthetic processGO:00181302150.022
Human
locomotionGO:00400113130.022
dorsal ventral pattern formationGO:00099531250.022
positive regulation of developmental processGO:0051094500.022
circadian sleep wake cycle processGO:002241020.022
regulation of tube sizeGO:003515020.022
inner ear developmentGO:00488391260.022
muscle structure developmentGO:00610611960.021
Zebrafish
embryonic skeletal system developmentGO:0048706970.021
cellular amino acid metabolic processGO:000652070.021
morphogenesis of an epitheliumGO:00020093330.021
positive regulation of cellular processGO:00485222010.020
Human Mouse Fly
aromatic compound biosynthetic processGO:00194382170.020
Human
embryonic viscerocranium morphogenesisGO:0048703520.020
neural tube patterningGO:0021532330.020
regulation of peptidyl tyrosine phosphorylationGO:005073010.020
Fly
response to monosaccharideGO:003428430.020
generation of neuronsGO:00486993850.020
positive regulation of cellular component biogenesisGO:004408930.020
nucleocytoplasmic transportGO:000691340.020
regulation of signal transductionGO:00099662250.020
Human Zebrafish Mouse Fly
cell morphogenesisGO:00009022890.020
regulation of developmental processGO:00507932470.020
Fly
proepicardium developmentGO:000334240.020
somitogenesisGO:0001756870.020
olfactory bulb developmentGO:002177240.020
glucose homeostasisGO:004259310.019
regulation of cell activationGO:005086510.019
negative regulation of synapse assemblyGO:005196420.019
circulatory system processGO:0003013870.019
polarized epithelial cell differentiationGO:003085940.019
cellular protein modification processGO:00064641000.019
Human Mouse Fly
cellular nitrogen compound biosynthetic processGO:00442712180.019
Human
embryonic heart tube morphogenesisGO:00031431080.018
olfactory lobe developmentGO:002198840.018
regulation of multicellular organism growthGO:004001440.018
histone lysine demethylationGO:007007620.018
response to hexoseGO:000974630.018
epidermal cell fate specificationGO:000995740.018
regulation of purine nucleotide catabolic processGO:003312120.018
cellular ketone metabolic processGO:0042180110.018
agingGO:000756820.018
regulation of dendrite developmentGO:005077330.018
multicellular organism growthGO:003526440.018
axon developmentGO:00615641660.018
regulation of neural precursor cell proliferationGO:200017730.018
stem cell developmentGO:0048864820.018
cellular response to lipopolysaccharideGO:007122230.018
neuron developmentGO:00486662620.018
transcription from rna polymerase ii promoterGO:0006366800.017
Human
embryo development ending in birth or egg hatchingGO:00097922710.017
regulation of blood vessel sizeGO:005088020.017
determination of heart left right asymmetryGO:00613711170.017
phagocytosis engulfmentGO:000691110.017
mechanoreceptor differentiationGO:0042490370.017
cell cycle g1 s phase transitionGO:004484310.017
protein importGO:001703830.017
positive regulation of stress activated mapk cascadeGO:003287430.017
nucleic acid transportGO:005065720.017
blood vessel morphogenesisGO:00485142160.017
circadian sleep wake cycle sleepGO:005080210.017
positive regulation of cellular amine metabolic processGO:003324000.017
neuron fate determinationGO:004866420.017
neurological system processGO:0050877620.017
Zebrafish
peptidyl lysine acetylationGO:001839420.016
axonogenesisGO:00074091520.016
macromolecule modificationGO:00434121110.016
Human Mouse Fly
cytokinesisGO:000091030.016
maintenance of locationGO:005123540.016
cellular component morphogenesisGO:00329893360.016
embryonic hemopoiesisGO:0035162530.016
nuclear transportGO:005116940.016
regulation of cell projection assemblyGO:006049140.016
cell matrix adhesionGO:000716040.016
cell proliferationGO:0008283800.016
alcohol biosynthetic processGO:004616520.016
sensory perception of chemical stimulusGO:000760630.016
angiogenesisGO:00015251580.016
cellular amine metabolic processGO:004410620.016
regulation of cellular amine metabolic processGO:003323800.016
camera type eye morphogenesisGO:00485931080.016
spermatid developmentGO:000728620.016
cell projection assemblyGO:0030031640.016
digestive tract morphogenesisGO:00485462310.016
Fly
rna localizationGO:000640340.016
germ line stem cell maintenanceGO:003071820.016
behaviorGO:0007610740.016
organonitrogen compound metabolic processGO:1901564740.016
protein secretionGO:000930610.016
homeostatic processGO:00425921420.016
epithelial cell developmentGO:0002064420.016
carbohydrate biosynthetic processGO:001605110.016
neuron projection morphogenesisGO:00488121610.016
proteolysis involved in cellular protein catabolic processGO:005160330.015
Human
regulation of cell substrate adhesionGO:001081010.015
modification dependent macromolecule catabolic processGO:004363230.015
Human
muscle organ developmentGO:00075171010.015
Zebrafish
negative regulation of developmental processGO:0051093650.015
Fly
regulation of transcription dna templatedGO:00063552130.015
Human
sensory system developmentGO:0048880760.015
regulation of cell differentiationGO:00455951420.015
Fly
locomotor rhythmGO:004547530.015
blood circulationGO:0008015870.015
connective tissue developmentGO:0061448990.015
negative regulation of macromolecule biosynthetic processGO:0010558480.015
positive regulation of cytosolic calcium ion concentrationGO:000720440.015
negative regulation of kinase activityGO:003367340.015
Fly
nucleobase containing compound biosynthetic processGO:00346542050.015
Human
nucleobase containing compound transportGO:001593120.015
sensory organ morphogenesisGO:00905962000.015
g1 s transition of mitotic cell cycleGO:000008210.015
regulation of cellular biosynthetic processGO:00313262450.014
Human
regulation of filopodium assemblyGO:005148920.014
regulation of jak stat cascadeGO:004642530.014
spermatid differentiationGO:004851520.014
positive regulation of transportGO:005105020.014
Human
cell morphogenesis involved in differentiationGO:00009041950.014
lipid storageGO:001991510.014
regulation of cellular amino acid metabolic processGO:000652100.014
neuron projection developmentGO:00311751800.014
epidermis developmentGO:0008544480.014
single organism metabolic processGO:00447102170.014
Human
regulation of nucleoside metabolic processGO:000911820.014
tissue remodelingGO:004877140.014
negative regulation of response to stimulusGO:00485851040.014
Human Mouse Fly
taxisGO:00423301090.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
Human Fly
ubiquitin dependent protein catabolic processGO:000651130.014
Human
striated muscle cell differentiationGO:00511461290.014
skin developmentGO:0043588540.014
glial cell migrationGO:000834730.014
axon ensheathment in central nervous systemGO:003229120.014
startle responseGO:000196440.014
negative regulation of metabolic processGO:0009892860.014
Human Fly
meiotic cell cycle processGO:190304630.014
somatic muscle developmentGO:000752540.014
neuron projection regenerationGO:0031102160.014
cellular response to molecule of bacterial originGO:007121930.014
response to carbohydrateGO:000974330.013
regulation of stem cell differentiationGO:200073640.013
inner ear receptor cell differentiationGO:0060113290.013
positive regulation of catabolic processGO:000989640.013
establishment of rna localizationGO:005123630.013
heart processGO:0003015710.013
striated muscle cell developmentGO:00550021080.013
establishment of localizationGO:00512342440.013
Human
negative regulation of multicellular organismal processGO:0051241690.013
Mouse Fly
growthGO:00400071740.013
Worm
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.013
regulation of cell developmentGO:00602841000.013
response to glucoseGO:000974930.013
forebrain developmentGO:0030900960.013
endocardial cushion formationGO:000327220.013
cellular aromatic compound metabolic processGO:00067252950.013
Human
regulation of dendrite morphogenesisGO:004881430.013
positive regulation of macromolecule metabolic processGO:0010604930.013
Human Fly
establishment of protein localization to organelleGO:007259440.013
regulation of cell deathGO:00109411030.013
regulation of neurogenesisGO:0050767870.013
organelle assemblyGO:00709251100.013
cell motilityGO:00488702440.013
regulation of blood pressureGO:000821710.013
nuclear importGO:005117030.013
hair cell differentiationGO:0035315320.013
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.013
neural tube developmentGO:0021915620.013
negative regulation of small gtpase mediated signal transductionGO:005105810.013
erythrocyte developmentGO:0048821240.013
oxoacid metabolic processGO:0043436310.013
septum transversum developmentGO:000334340.013
developmental growthGO:00485891660.013
regulation of signalingGO:00230512350.013
embryonic cranial skeleton morphogenesisGO:0048701900.012
protein acetylationGO:000647320.012
positive regulation of neurogenesisGO:0050769240.012
regulation of cell communicationGO:00106462320.012
Human Zebrafish Mouse Fly
gtp metabolic processGO:004603940.012
regulation of p38mapk cascadeGO:190074410.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
phosphate containing compound metabolic processGO:00067961080.012
Human Mouse Fly
mesenchymal cell differentiationGO:0048762870.012
intracellular signal transductionGO:0035556850.012
Human Mouse
carbohydrate homeostasisGO:003350010.012
rhombomere 5 developmentGO:002157140.012
response to abiotic stimulusGO:00096281220.012
central nervous system neuron differentiationGO:0021953740.012
cell morphogenesis involved in neuron differentiationGO:00486671630.012
cellular response to external stimulusGO:007149620.012
gtp catabolic processGO:000618420.012
regulation of reproductive processGO:200024140.012
regulation of transcription from rna polymerase ii promoterGO:00063571140.012
positive regulation of cell developmentGO:0010720250.012
regulation of ion transmembrane transporter activityGO:003241220.012
auditory receptor cell fate determinationGO:004266820.012
myeloid cell developmentGO:0061515320.012
smooth muscle contractionGO:000693920.012
regulation of protein transportGO:005122330.012
positive regulation of cell activationGO:005086710.012
endocrine system developmentGO:0035270650.012
positive regulation of cell adhesionGO:004578510.012
amine metabolic processGO:000930820.012
negative regulation of neurogenesisGO:0050768200.012
response to organic substanceGO:00100331530.012
Human
positive regulation of cellular catabolic processGO:003133130.012
regulation of inflammatory responseGO:005072720.012
Fly
positive regulation of cellular amino acid metabolic processGO:004576400.012
negative regulation of protein phosphorylationGO:000193340.012
Fly
nerve developmentGO:0021675450.011
cell fate commitmentGO:0045165990.011
actin polymerization or depolymerizationGO:000815420.011
response to woundingGO:00096111160.011
Fly
erythrocyte differentiationGO:0030218540.011
cell cycle arrestGO:000705010.011
protein localization to nucleusGO:003450430.011
stem cell differentiationGO:00488631170.011
eye morphogenesisGO:00485921440.011
embryonic heart tube developmentGO:00350501330.011
muscle cell developmentGO:00550011150.011
cell fate specificationGO:0001708680.011
immune system developmentGO:00025201910.011
Fly
regulation of nucleocytoplasmic transportGO:004682220.011
inner ear receptor cell fate commitmentGO:006012040.011
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.011
regulation of gtpase activityGO:004308720.011
production of molecular mediator of immune responseGO:000244020.011
cellular response to extracellular stimulusGO:003166820.011
sex determinationGO:000753010.011
regulation of neuron differentiationGO:0045664560.011
regulation of protein complex assemblyGO:004325430.011
lens fiber cell developmentGO:007030730.011
positive regulation of transcription dna templatedGO:0045893570.011
mitotic cell cycle embryonicGO:004544820.011
regulation of nucleotide catabolic processGO:003081120.011
heart contractionGO:0060047710.011
regulation of establishment of protein localizationGO:007020140.011
negative regulation of macromolecule metabolic processGO:0010605760.011
Human Fly
lateral line system developmentGO:0048925760.011
phosphorylationGO:0016310690.011
Human Mouse Fly
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.011
renal system developmentGO:0072001940.011
cellular component disassemblyGO:002241110.011
internal peptidyl lysine acetylationGO:001839320.011
negative regulation of biosynthetic processGO:0009890550.011
negative regulation of cellular biosynthetic processGO:0031327550.011
macromolecular complex disassemblyGO:003298410.011
small molecule metabolic processGO:0044281770.011
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.011
Human
modification dependent protein catabolic processGO:001994130.011
Human
positive regulation of nucleotide catabolic processGO:003081310.011
positive regulation of jnk cascadeGO:004633030.011
positive regulation of multicellular organismal processGO:0051240520.011
retina development in camera type eyeGO:00600411460.010
positive regulation of notch signaling pathwayGO:004574730.010
regulation of cytoplasmic transportGO:190364940.010
protein polymerizationGO:005125840.010
negative regulation of cellular metabolic processGO:0031324770.010
Human Fly
response to stressGO:00069502630.010
Human Fly
guanosine containing compound metabolic processGO:190106840.010
endoderm developmentGO:0007492490.010
rhombomere 6 developmentGO:002157240.010
transportGO:00068102200.010
Human
primary neural tube formationGO:001402010.010
hatchingGO:003518840.010
peripheral nervous system developmentGO:0007422550.010
endocardial cushion morphogenesisGO:000320330.010
single organism nuclear importGO:190259330.010
neural crest cell differentiationGO:0014033720.010
positive regulation of nucleic acid templated transcriptionGO:1903508570.010
sensory perception of mechanical stimulusGO:0050954160.010
lateral line developmentGO:0048882660.010
activation of mapkkk activityGO:000018510.010
negative regulation of translationGO:001714810.010
cellular response to chemical stimulusGO:00708871570.010

arrb2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.054
cardiovascular system diseaseDOID:128700.020
nervous system diseaseDOID:86300.018
disease of cellular proliferationDOID:1456600.012
disease of metabolismDOID:001466700.011
sensory system diseaseDOID:005015500.010
eye and adnexa diseaseDOID:149200.010