Danio rerio

22 known processes

tgfbi

transforming growth factor, beta-induced

(Aliases: zgc:110495,hm:zeh0933,BIGH3,wu:fa13f05,big-h3)

tgfbi biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of biological processGO:00485193040.736
embryonic skeletal system developmentGO:0048706970.721
ameboidal type cell migrationGO:00016671430.717
collagen metabolic processGO:003296320.617
nucleobase containing compound metabolic processGO:00061392740.612
hindbrain developmentGO:0030902910.589
regulation of chondrocyte differentiationGO:003233010.560
regulation of rna biosynthetic processGO:20011412130.555
locomotionGO:00400113130.548
digestive system developmentGO:00551232890.528
mesenchymal cell differentiationGO:0048762870.511
regulation of cell differentiationGO:00455951420.510
larval developmentGO:000216420.486
regulation of multicellular organismal developmentGO:20000262230.485
aromatic compound biosynthetic processGO:00194382170.436
fin regenerationGO:0031101510.432
regulation of autophagyGO:001050630.429
cell motilityGO:00488702440.424
angiogenesisGO:00015251580.406
Human
embryonic organ developmentGO:00485683810.402
cartilage developmentGO:0051216960.397
regulation of transcription dna templatedGO:00063552130.368
biosynthetic processGO:00090582940.368
response to vitaminGO:003327330.344
nucleic acid templated transcriptionGO:00976591810.331
nucleic acid metabolic processGO:00903042440.299
macromolecule biosynthetic processGO:00090592270.298
formation of primary germ layerGO:0001704620.296
cell proliferationGO:0008283800.290
epithelial to mesenchymal transitionGO:0001837210.289
epithelial cell differentiationGO:00308551160.286
inner ear receptor cell differentiationGO:0060113290.284
nuclear transportGO:005116940.283
connective tissue developmentGO:0061448990.273
positive regulation of gene expressionGO:0010628710.271
nucleocytoplasmic transportGO:000691340.270
transcription dna templatedGO:00063511810.269
regulation of biosynthetic processGO:00098892500.246
regulation of developmental processGO:00507932470.242
positive regulation of macromolecule metabolic processGO:0010604930.240
chordate embryonic developmentGO:00430092710.240
blood vessel developmentGO:00015682460.238
Human
regionalizationGO:00030022740.236
regulation of protein transportGO:005122330.225
organic substance biosynthetic processGO:19015762890.216
fin morphogenesisGO:0033334530.215
digestive tract morphogenesisGO:00485462310.211
vasculature developmentGO:00019442780.209
Human
mesenchymal cell developmentGO:0014031780.208
neural crest cell differentiationGO:0014033720.204
organic acid metabolic processGO:0006082310.203
regulation of dna replicationGO:000627530.202
fin developmentGO:0033333770.201
multicellular organismal macromolecule metabolic processGO:004425920.196
regulation of rna metabolic processGO:00512522240.196
nitrogen compound metabolic processGO:00068073190.196
single organism nuclear importGO:190259330.190
positive regulation of response to external stimulusGO:003210390.186
localization of cellGO:00516742440.183
gland developmentGO:00487321430.180
gene expressionGO:00104672520.180
endoderm developmentGO:0007492490.179
ossificationGO:0001503230.179
tissue remodelingGO:004877140.179
blood vessel morphogenesisGO:00485142160.179
Human
signal transductionGO:00071654550.174
regenerationGO:0031099910.173
regulation of multicellular organismal processGO:00512392770.172
skeletal system morphogenesisGO:00487051020.171
regulation of signalingGO:00230512350.170
epithelial cell migrationGO:0010631250.170
cellular component movementGO:00069283350.168
embryonic cranial skeleton morphogenesisGO:0048701900.168
organic cyclic compound metabolic processGO:19013603010.168
nuclear importGO:005117030.167
hematopoietic or lymphoid organ developmentGO:00485341910.166
somitogenesisGO:0001756870.165
embryonic limb morphogenesisGO:003032620.163
protein localization to nucleusGO:003450430.160
regulation of response to nutrient levelsGO:003210710.156
nucleobase containing compound biosynthetic processGO:00346542050.155
glial cell migrationGO:000834730.154
heterocycle biosynthetic processGO:00181302150.154
appendage developmentGO:0048736800.148
heart joggingGO:0003146400.147
regulation of gene expressionGO:00104682650.144
stem cell developmentGO:0048864820.143
positive regulation of rna biosynthetic processGO:1902680570.140
response to amino acidGO:004320020.139
rna metabolic processGO:00160702190.138
regulation of establishment of protein localizationGO:007020140.137
cell fate specificationGO:0001708680.136
gliogenesisGO:0042063450.136
digestive tract developmentGO:00485652650.134
purine containing compound metabolic processGO:0072521290.134
chromatin organizationGO:0006325220.134
establishment of protein localization to organelleGO:007259440.134
gastrulationGO:00073692080.133
endothelial cell migrationGO:0043542190.133
brain developmentGO:00074202930.132
positive regulation of nucleic acid templated transcriptionGO:1903508570.128
regulation of primary metabolic processGO:00800903110.124
cellular nitrogen compound biosynthetic processGO:00442712180.124
positive regulation of cellular biosynthetic processGO:0031328680.124
positive regulation of cellular processGO:00485222010.123
regulation of intracellular protein transportGO:003315730.121
protein targeting to nucleusGO:004474430.121
morphogenesis of an epitheliumGO:00020093330.121
extrinsic apoptotic signaling pathwayGO:009719130.120
hard palate developmentGO:006002240.120
mesodermal cell migrationGO:0008078120.120
positive regulation of wound healingGO:009030310.120
cell deathGO:00082191210.119
agingGO:000756820.119
regulation of cellular macromolecule biosynthetic processGO:20001122220.119
cellular ketone metabolic processGO:0042180110.118
multicellular organismal metabolic processGO:004423620.118
anterior posterior pattern specificationGO:00099521520.115
determination of dorsal ventral asymmetryGO:0048262340.113
cellular response to nutrient levelsGO:003166920.110
cellular macromolecule metabolic processGO:00442603910.110
single organism metabolic processGO:00447102170.109
mesenchyme developmentGO:00604851270.106
response to nutrientGO:000758430.106
appendage morphogenesisGO:0035107560.106
endoderm formationGO:0001706290.103
regulation of nucleobase containing compound metabolic processGO:00192192500.102
regulation of protein localization to nucleusGO:190018020.102
single organism localizationGO:19025782250.102
urogenital system developmentGO:0001655970.101
stem cell differentiationGO:00488631170.100
cellular macromolecule biosynthetic processGO:00346452240.100
intracellular signal transductionGO:0035556850.100
positive regulation of cell differentiationGO:0045597300.100
cartilage morphogenesisGO:0060536130.100
negative regulation of canonical wnt signaling pathwayGO:0090090210.098
regulation of cartilage developmentGO:006103570.098
endocardial cushion formationGO:000327220.097
immune system processGO:00023762410.097
positive regulation of rna metabolic processGO:0051254590.095
tube morphogenesisGO:00352393490.094
sprouting angiogenesisGO:0002040530.094
generation of neuronsGO:00486993850.092
positive regulation of signalingGO:0023056560.092
protein acylationGO:004354330.092
exocrine pancreas developmentGO:0031017280.092
small molecule metabolic processGO:0044281770.091
cellular nitrogen compound metabolic processGO:00346412900.089
ectodermal placode developmentGO:0071696370.087
wound healingGO:0042060900.086
neural crest cell developmentGO:0014032620.085
regulation of cell deathGO:00109411030.085
regulation of cellular ketone metabolic processGO:001056570.084
negative regulation of epithelial cell proliferationGO:005068010.082
regulation of cytoplasmic transportGO:190364940.082
cellular response to organic substanceGO:00713101050.082
cellular response to extracellular stimulusGO:003166820.080
positive regulation of cell cycleGO:004578730.079
apoptotic processGO:00069151160.078
multicellular organism growthGO:003526440.077
regulation of epithelial to mesenchymal transitionGO:001071730.077
cellular response to retinoic acidGO:007130010.077
otic vesicle developmentGO:0071599420.076
peptide transportGO:001583310.076
positive regulation of muscle cell differentiationGO:005114910.076
endodermal cell differentiationGO:0035987190.076
response to organic cyclic compoundGO:0014070510.076
positive regulation of striated muscle cell differentiationGO:005115510.074
cell fate commitmentGO:0045165990.074
negative regulation of cellular processGO:00485232830.074
oxoacid metabolic processGO:0043436310.073
embryonic organ morphogenesisGO:00485622740.073
tissue regenerationGO:0042246740.073
cell migrationGO:00164772370.073
embryonic digestive tract developmentGO:004856640.072
regulation of bindingGO:005109830.072
cellular response to external stimulusGO:007149620.072
retina development in camera type eyeGO:00600411460.071
regulation of programmed cell deathGO:00430671010.071
macromolecule glycosylationGO:004341390.071
regulation of cell motilityGO:2000145460.070
cellular component morphogenesisGO:00329893360.070
response to organic substanceGO:00100331530.070
metencephalon developmentGO:0022037270.070
canonical wnt signaling pathwayGO:0060070480.069
heart morphogenesisGO:00030071560.069
regulation of cell activationGO:005086510.068
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.068
regulation of nitrogen compound metabolic processGO:00511712510.068
regulation of protein targetingGO:190353320.068
cellular biosynthetic processGO:00442492860.067
regulation of response to stimulusGO:00485832690.067
inner ear receptor cell developmentGO:0060119200.067
liver developmentGO:0001889960.066
regulation of cell morphogenesisGO:0022604420.065
cellular response to chemical stimulusGO:00708871570.064
response to hormoneGO:0009725480.063
negative regulation of cell deathGO:0060548600.063
regulation of nucleic acid templated transcriptionGO:19035062130.063
response to abiotic stimulusGO:00096281220.063
regulation of nucleocytoplasmic transportGO:004682220.063
cell morphogenesisGO:00009022890.063
cell growthGO:0016049570.062
response to monosaccharideGO:003428430.062
positive regulation of epithelial cell differentiationGO:003085820.062
outflow tract morphogenesisGO:000315110.061
positive regulation of metabolic processGO:00098931080.060
positive regulation of histone deacetylationGO:003106510.060
regulation of cell communicationGO:00106462320.060
deathGO:00162651210.059
protein importGO:001703830.058
alcohol biosynthetic processGO:004616520.058
regulation of canonical wnt signaling pathwayGO:0060828340.057
ectodermal placode morphogenesisGO:0071697320.057
regulation of epithelial cell proliferationGO:005067830.056
regulation of cellular amine metabolic processGO:003323800.056
positive regulation of cell adhesionGO:004578510.055
mesoderm morphogenesisGO:0048332510.055
cell migration involved in heart developmentGO:0060973220.054
response to glucoseGO:000974930.054
heart developmentGO:00075073130.053
cell differentiation in spinal cordGO:0021515400.053
organic cyclic compound biosynthetic processGO:19013622230.053
phosphate containing compound metabolic processGO:00067961080.052
pectoral fin morphogenesisGO:0035138290.052
negative regulation of myeloid cell differentiationGO:004563810.052
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.051
segmentationGO:0035282970.051
response to acid chemicalGO:0001101170.051
carboxylic acid metabolic processGO:0019752220.051
collagen fibril organizationGO:003019910.050
skeletal system developmentGO:00015011810.050
membrane invaginationGO:001032410.050
sensory system developmentGO:0048880760.049
proteolysis involved in cellular protein catabolic processGO:005160330.049
developmental growth involved in morphogenesisGO:0060560860.049
regulation of wnt signaling pathwayGO:0030111530.049
endocardial cushion morphogenesisGO:000320330.049
regulation of cell sizeGO:0008361290.049
cellular protein catabolic processGO:004425740.049
endothelium developmentGO:0003158250.048
response to chemicalGO:00422213200.048
negative regulation of cytoplasmic transportGO:190365020.048
regulation of macromolecule metabolic processGO:00602553170.048
regulation of localizationGO:00328791040.046
regulation of biological qualityGO:00650082630.045
specification of symmetryGO:00097992040.045
response to woundingGO:00096111160.045
bone developmentGO:0060348140.045
ear morphogenesisGO:0042471640.044
embryo development ending in birth or egg hatchingGO:00097922710.044
regulation of cell substrate adhesionGO:001081010.044
regulation of cyclic nucleotide metabolic processGO:0030799150.044
regulation of cell migrationGO:0030334400.043
regulation of protein import into nucleusGO:004230620.043
leukocyte proliferationGO:007066110.043
regulation of intracellular signal transductionGO:1902531570.043
immune system developmentGO:00025201910.043
negative regulation of chemotaxisGO:005092240.042
positive regulation of cellular amine metabolic processGO:003324000.042
vasculogenesisGO:0001570410.042
regulation of extrinsic apoptotic signaling pathwayGO:200123630.042
cellular aromatic compound metabolic processGO:00067252950.042
mesoderm developmentGO:0007498880.042
positive regulation of nitrogen compound metabolic processGO:0051173690.042
cellular response to lipidGO:0071396390.042
myeloid cell differentiationGO:0030099860.041
columnar cuboidal epithelial cell differentiationGO:0002065380.041
negative regulation of gene expressionGO:0010629650.041
cellular amine metabolic processGO:004410620.041
growthGO:00400071740.041
negative regulation of cellular component movementGO:0051271180.041
negative regulation of macromolecule metabolic processGO:0010605760.040
regulation of macromolecule biosynthetic processGO:00105562250.040
proteolysisGO:0006508380.040
response to hexoseGO:000974630.040
regulation of tissue remodelingGO:003410320.039
enzyme linked receptor protein signaling pathwayGO:00071671060.039
pancreas developmentGO:0031016840.039
regulation of molecular functionGO:0065009700.039
cell cycle arrestGO:000705010.039
developmental programmed cell deathGO:001062340.039
regulation of protein bindingGO:004339330.038
photoreceptor cell differentiationGO:0046530550.038
lateral inhibitionGO:004633110.036
positive regulation of chromosome organizationGO:200125210.036
pectoral fin developmentGO:0033339500.036
regulation of stem cell differentiationGO:200073640.035
epithelial cell proliferationGO:0050673170.035
signal transduction in absence of ligandGO:003803410.035
negative regulation of apoptotic processGO:0043066550.035
posterior lateral line developmentGO:0048916380.035
negative regulation of axon guidanceGO:190266810.035
wnt signaling pathwayGO:0016055800.035
regulation of cellular amino acid metabolic processGO:000652100.034
regulation of catalytic activityGO:0050790550.034
regulation of locomotionGO:0040012550.034
regulation of cellular component movementGO:0051270550.034
cell cycleGO:0007049930.034
negative regulation of cellular biosynthetic processGO:0031327550.034
autophagyGO:000691440.033
positive regulation of biological processGO:00485182530.033
response to corticosteroidGO:003196010.033
response to other organismGO:0051707970.033
regulation of cysteine type endopeptidase activityGO:2000116210.033
endodermal cell fate specificationGO:0001714170.033
negative regulation of response to dna damage stimulusGO:200102130.033
muscle cell differentiationGO:00426921390.033
gene silencing by rnaGO:003104740.032
direct ossificationGO:003607230.032
craniofacial suture morphogenesisGO:009709420.032
regulation of multicellular organism growthGO:004001440.031
cell substrate adhesionGO:003158940.031
convergent extension involved in gastrulationGO:0060027710.031
glucose homeostasisGO:004259310.031
negative regulation of macromolecule biosynthetic processGO:0010558480.031
fat soluble vitamin metabolic processGO:000677540.031
regulation of dna metabolic processGO:0051052110.031
endocrine system developmentGO:0035270650.031
regulation of cell morphogenesis involved in differentiationGO:0010769380.031
ear developmentGO:00435831270.030
positive regulation of cell motilityGO:2000147110.030
peptidyl lysine acetylationGO:001839420.030
regulation of apoptotic processGO:0042981980.030
positive regulation of signal transductionGO:0009967560.030
otic placode formationGO:0043049230.029
inner ear morphogenesisGO:0042472630.029
sensory organ morphogenesisGO:00905962000.029
positive regulation of cell proliferationGO:0008284150.029
transportGO:00068102200.029
germ line stem cell maintenanceGO:003071820.029
epithelial cell developmentGO:0002064420.029
negative regulation of cell proliferationGO:000828580.029
positive regulation of cellular component movementGO:0051272110.029
phagocytosisGO:000690930.029
purine ribonucleotide biosynthetic processGO:0009152200.029
ribonucleotide biosynthetic processGO:0009260200.029
positive regulation of response to stimulusGO:0048584800.029
cellular amino acid metabolic processGO:000652070.029
pigmentationGO:0043473850.028
rna biosynthetic processGO:00327741810.028
camera type eye morphogenesisGO:00485931080.028
regulation of response to extracellular stimulusGO:003210410.028
cardioblast migration to the midline involved in heart field formationGO:006097570.028
osteoclast differentiationGO:003031610.027
cellular process involved in reproduction in multicellular organismGO:0022412280.027
hemopoiesisGO:00300971830.027
response to glucocorticoidGO:005138410.027
heterocycle metabolic processGO:00464832900.027
polarized epithelial cell differentiationGO:003085940.027
positive regulation of transportGO:005105020.027
single organism biosynthetic processGO:0044711710.027
trabecula formationGO:006034320.026
nucleotide metabolic processGO:0009117280.026
covalent chromatin modificationGO:0016569200.026
regulation of anatomical structure morphogenesisGO:00226031300.026
kidney morphogenesisGO:0060993150.026
positive regulation of biosynthetic processGO:0009891680.026
regulation of axonogenesisGO:0050770320.026
eye field cell fate commitment involved in camera type eye formationGO:006089830.026
determination of left right symmetryGO:00073681790.026
regulation of cell proliferationGO:0042127370.026
negative regulation of cell cycleGO:0045786140.025
cell morphogenesis involved in differentiationGO:00009041950.025
head developmentGO:00603223030.025
purine ribonucleoside biosynthetic processGO:004612920.025
cranial suture morphogenesisGO:006036310.025
optic nerve developmentGO:0021554150.025
response to stressGO:00069502630.025
neuron remodelingGO:001632210.025
lipid storageGO:001991510.025
positive regulation of nucleobase containing compound metabolic processGO:0045935690.025
establishment of cell polarityGO:0030010180.025
bone remodelingGO:004684920.024
ras protein signal transductionGO:000726570.024
somite developmentGO:0061053960.024
embryonic camera type eye developmentGO:0031076290.024
positive regulation of cellular metabolic processGO:0031325940.024
axon extension involved in axon guidanceGO:0048846100.024
otic vesicle formationGO:0030916270.024
multicellular organismal response to stressGO:003355520.024
negative regulation of transcription dna templatedGO:0045892450.024
positive regulation of epithelial cell migrationGO:001063420.024
lipid metabolic processGO:0006629520.024
dna biosynthetic processGO:007189730.024
protein metabolic processGO:00195381830.024
amine metabolic processGO:000930820.023
central nervous system neuron differentiationGO:0021953740.023
regulation of proteolysisGO:0030162240.023
response to transition metal nanoparticleGO:1990267280.023
negative regulation of nucleic acid templated transcriptionGO:1903507450.023
neural crest cell migrationGO:0001755420.023
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.023
regulation of immune system processGO:0002682340.023
epithelial cell proliferation involved in liver morphogenesisGO:007257520.023
photoreceptor cell fate commitmentGO:004655210.022
cell migration involved in sprouting angiogenesisGO:000204280.022
positive regulation of dna metabolic processGO:005105410.022
regulation of cell cycle processGO:0010564200.022
single organism cellular localizationGO:1902580460.022
spinal cord motor neuron differentiationGO:0021522260.022
negative regulation of programmed cell deathGO:0043069580.022
cellular catabolic processGO:0044248270.022
internal protein amino acid acetylationGO:000647520.022
regulation of peptidase activityGO:0052547230.022
leukocyte activationGO:0045321120.022
positive regulation of developmental processGO:0051094500.022
endocytosisGO:0006897160.022
epithelium migrationGO:0090132250.022
hepaticobiliary system developmentGO:0061008980.022
muscle structure developmentGO:00610611960.022
epithelial cell morphogenesisGO:000338220.022
negative regulation of rna biosynthetic processGO:1902679450.022
epithalamus developmentGO:0021538100.022
embryonic appendage morphogenesisGO:0035113300.022
neuromast primordium migrationGO:0048883120.022
establishment of localization in cellGO:0051649770.021
cell migration to the midline involved in heart developmentGO:0003318120.021
olfactory lobe developmentGO:002198840.021
determination of heart left right asymmetryGO:00613711170.021
cellular response to endogenous stimulusGO:0071495680.021
cell cycle processGO:0022402530.021
cell proliferation in forebrainGO:002184630.021
phosphorus metabolic processGO:00067931090.021
programmed cell deathGO:00125011190.021
positive regulation of cellular protein metabolic processGO:0032270220.021
cell migration involved in heart formationGO:0060974100.021
internal peptidyl lysine acetylationGO:001839320.020
ectodermal placode formationGO:0060788260.020
protein import into nucleusGO:000660630.020
defense response to bacteriumGO:0042742220.020
vestibular receptor cell developmentGO:006011830.020
cardioblast differentiationGO:001000290.020
eye morphogenesisGO:00485921440.020
protein maturationGO:0051604120.020
chemosensory behaviorGO:000763510.020
positive regulation of transcription dna templatedGO:0045893570.020
cerebellum developmentGO:0021549170.020
ribonucleoside biosynthetic processGO:004245520.020
cytosolic calcium ion transportGO:006040130.020
cell cell signalingGO:0007267520.020
cardiac conduction system developmentGO:000316110.020
single organism transportGO:00447652060.020
lateral mesoderm developmentGO:0048368230.020
cell surface receptor signaling pathwayGO:00071663250.019
trigeminal nerve developmentGO:002155930.019
developmental growthGO:00485891660.019
regulation of cell matrix adhesionGO:000195210.019
tissue migrationGO:0090130370.019
primary neural tube formationGO:001402010.019
retinal cone cell developmentGO:004654980.019
olfactory placode developmentGO:0071698120.019
axon extensionGO:0048675450.019
peripheral nervous system developmentGO:0007422550.019
inner ear developmentGO:00488391260.019
neuron developmentGO:00486662620.019
pronephros morphogenesisGO:0072114140.019
cyclic nucleotide metabolic processGO:0009187180.019
positive regulation of immune effector processGO:000269930.019
positive regulation of macromolecule biosynthetic processGO:0010557590.018
regulation of organ morphogenesisGO:2000027350.018
embryonic digestive tract morphogenesisGO:004855730.018
nucleoside phosphate biosynthetic processGO:1901293210.018
camera type eye developmentGO:00430102220.018
organelle organizationGO:00069962270.018
regulation of cell developmentGO:00602841000.018
chromatin modificationGO:0016568210.018
histone modificationGO:0016570200.018
activation of mapk activityGO:000018730.018
regulation of signal transductionGO:00099662250.018
positive regulation of catalytic activityGO:0043085250.018
carbohydrate homeostasisGO:003350010.018
cell migration involved in gastrulationGO:0042074790.018
nucleotide biosynthetic processGO:0009165210.018
regulation of metabolic processGO:00192223590.018
positive regulation of cell communicationGO:0010647560.018
positive regulation of cell activationGO:005086710.018
embryonic skeletal system morphogenesisGO:0048704930.018
neuron projection extensionGO:1990138450.018
negative regulation of protein transportGO:005122430.018
nucleobase containing small molecule metabolic processGO:0055086320.017
positive regulation of i kappab kinase nf kappab signalingGO:004312330.017

tgfbi disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
bone diseaseDOID:008000100.103
musculoskeletal system diseaseDOID:1700.103
disease of anatomical entityDOID:700.103
connective tissue diseaseDOID:6500.103
neuropathyDOID:87000.038
charcot marie tooth diseaseDOID:1059500.038
nervous system diseaseDOID:86300.038
neuromuscular diseaseDOID:44000.038
charcot marie tooth disease type 4DOID:005054100.038
bone development diseaseDOID:008000600.036
osteochondrodysplasiaDOID:225600.036
disease of cellular proliferationDOID:1456600.022
disease of metabolismDOID:001466700.022