Danio rerio

27 known processes

plp1a

proteolipid protein 1a

(Aliases: wu:fc27f01,wu:fj42d08,DM20,zgc:110499,plp1,wu:fj36d03,DMalpha2c)

plp1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
action potentialGO:0001508190.914
cell morphogenesisGO:00009022890.898
regulation of gene expressionGO:00104682650.887
Mouse
transmission of nerve impulseGO:0019226190.829
stem cell fate commitmentGO:004886510.826
head developmentGO:00603223030.817
Human
sensory organ developmentGO:00074233930.760
astrocyte differentiationGO:004870810.732
Mouse
oligodendrocyte developmentGO:001400370.720
Mouse
multicellular organismal signalingGO:0035637220.702
neuron migrationGO:0001764220.595
regulation of macromolecule metabolic processGO:00602553170.555
Mouse
generation of neuronsGO:00486993850.548
Zebrafish Mouse
gene expressionGO:00104672520.491
Mouse
gliogenesisGO:0042063450.488
Mouse
cell part morphogenesisGO:00329902460.467
organic substance biosynthetic processGO:19015762890.457
Mouse
axonogenesisGO:00074091520.446
neuron projection morphogenesisGO:00488121610.425
neuron developmentGO:00486662620.421
Zebrafish Mouse
axon guidanceGO:0007411860.421
cellular macromolecule metabolic processGO:00442603910.377
neuron projection guidanceGO:0097485860.372
positive regulation of gene expressionGO:0010628710.343
Mouse
central nervous system developmentGO:00074173870.341
Human Mouse
glial cell developmentGO:0021782200.337
Mouse
regulation of cell differentiationGO:00455951420.322
regulation of membrane potentialGO:0042391230.318
neurological system processGO:0050877620.305
neuronal action potentialGO:0019228180.300
eye developmentGO:00016542770.299
ensheathment of neuronsGO:0007272180.299
response to stressGO:00069502630.287
Mouse
myelinationGO:0042552180.281
glial cell migrationGO:000834730.267
neuroblast fate determinationGO:000740010.254
response to woundingGO:00096111160.247
chemotaxisGO:00069351040.238
cell projection morphogenesisGO:00488582440.229
positive regulation of biological processGO:00485182530.227
Mouse
regulation of rna metabolic processGO:00512522240.225
camera type eye developmentGO:00430102220.221
oligodendrocyte differentiationGO:0048709230.220
Mouse
motor neuron axon guidanceGO:0008045230.210
neuron differentiationGO:00301823530.201
Zebrafish Mouse
neuroblast fate commitmentGO:001401710.193
hindbrain developmentGO:0030902910.192
neural nucleus developmentGO:0048857150.183
Human
cell motilityGO:00488702440.182
regulation of macromolecule biosynthetic processGO:00105562250.177
axon developmentGO:00615641660.168
Mouse
gas transportGO:001566930.166
regulation of primary metabolic processGO:00800903110.163
vasculature developmentGO:00019442780.148
regulation of glial cell differentiationGO:004568540.143
cellular aromatic compound metabolic processGO:00067252950.142
response to chemicalGO:00422213200.142
response to external stimulusGO:00096052640.138
sensory organ morphogenesisGO:00905962000.137
negative regulation of cellular processGO:00485232830.137
deathGO:00162651210.135
wound healingGO:0042060900.134
regulation of cellular metabolic processGO:00313233200.132
regulation of biosynthetic processGO:00098892500.131
heterocycle biosynthetic processGO:00181302150.130
cellular macromolecule biosynthetic processGO:00346452240.129
single organism reproductive processGO:0044702400.125
brain developmentGO:00074202930.125
Human
neuroblast differentiationGO:001401610.125
polarized epithelial cell differentiationGO:003085940.121
cellular biosynthetic processGO:00442492860.121
Mouse
regulation of neurogenesisGO:0050767870.119
locomotionGO:00400113130.118
taxisGO:00423301090.117
regenerationGO:0031099910.116
regulation of mrna processingGO:005068430.111
regulation of rna biosynthetic processGO:20011412130.108
chordate embryonic developmentGO:00430092710.108
regulation of biological qualityGO:00650082630.104
neuron projection developmentGO:00311751800.103
Zebrafish Mouse
schwann cell differentiationGO:001403790.102
regulation of nitrogen compound metabolic processGO:00511712510.102
behaviorGO:0007610740.100
regulation of cellular biosynthetic processGO:00313262450.100
glucose importGO:004632320.099
muscle organ developmentGO:00075171010.098
skeletal muscle organ developmentGO:0060538780.098
digestive tract developmentGO:00485652650.096
biosynthetic processGO:00090582940.094
Mouse
blood vessel morphogenesisGO:00485142160.093
cell morphogenesis involved in neuron differentiationGO:00486671630.093
stem cell fate determinationGO:004886710.090
regulation of nucleic acid templated transcriptionGO:19035062130.088
stem cell differentiationGO:00488631170.087
morphogenesis of an epitheliumGO:00020093330.084
water homeostasisGO:003010440.083
enzyme linked receptor protein signaling pathwayGO:00071671060.083
agingGO:000756820.080
nucleobase containing compound metabolic processGO:00061392740.079
cellular component movementGO:00069283350.078
programmed cell deathGO:00125011190.076
central nervous system myelinationGO:002201020.076
Mouse
cell morphogenesis involved in differentiationGO:00009041950.075
regulation of oligodendrocyte differentiationGO:004871310.072
cell projection organizationGO:00300302840.072
Zebrafish Mouse
schwann cell developmentGO:001404490.072
larval developmentGO:000216420.071
regulation of metabolic processGO:00192223590.071
Mouse
regulation of programmed cell deathGO:00430671010.067
cell migrationGO:00164772370.067
regulation of signalingGO:00230512350.067
angioblast cell migration involved in selective angioblast sproutingGO:003547540.066
regulation of neuron differentiationGO:0045664560.065
system processGO:00030081850.065
nitrogen compound metabolic processGO:00068073190.064
negative regulation of apoptotic processGO:0043066550.062
positive regulation of cell cycleGO:004578730.062
central nervous system neuron differentiationGO:0021953740.061
protein metabolic processGO:00195381830.061
regulation of cellular macromolecule biosynthetic processGO:20001122220.061
rna metabolic processGO:00160702190.059
tissue regenerationGO:0042246740.059
skeletal system developmentGO:00015011810.059
regulation of developmental processGO:00507932470.058
developmental growthGO:00485891660.058
apoptotic processGO:00069151160.057
regulation of multicellular organismal developmentGO:20000262230.057
rna biosynthetic processGO:00327741810.056
nerve developmentGO:0021675450.056
cell surface receptor signaling pathwayGO:00071663250.056
growthGO:00400071740.053
axon ensheathmentGO:0008366180.053
regulation of nucleobase containing compound metabolic processGO:00192192500.053
neuron recognitionGO:0008038180.052
pancreatic a cell developmentGO:000332220.052
positive regulation of developmental processGO:0051094500.050
embryonic heart tube developmentGO:00350501330.050
negative regulation of cell deathGO:0060548600.049
regulation of cell morphogenesisGO:0022604420.049
telencephalon developmentGO:0021537140.049
regulation of multicellular organismal processGO:00512392770.048
neuron projection regenerationGO:0031102160.048
heterocycle metabolic processGO:00464832900.047
stem cell proliferationGO:007208940.046
ventral spinal cord interneuron fate commitmentGO:006057930.046
regulation of cell communicationGO:00106462320.045
cellular response to growth factor stimulusGO:0071363390.045
mesenchyme developmentGO:00604851270.045
apoptotic process involved in morphogenesisGO:006056120.044
central nervous system neuron developmentGO:0021954290.043
positive regulation of cellular biosynthetic processGO:0031328680.043
positive regulation of gliogenesisGO:001401520.042
positive regulation of metabolic processGO:00098931080.041
Mouse
convergent extension involved in organogenesisGO:0060029100.041
compound eye developmentGO:004874920.041
cell proliferation in forebrainGO:002184630.040
response to drugGO:004249330.040
tissue remodelingGO:004877140.040
positive regulation of rna biosynthetic processGO:1902680570.040
regulation of filopodium assemblyGO:005148920.040
Zebrafish
localization of cellGO:00516742440.039
mesenchymal cell developmentGO:0014031780.039
negative regulation of cysteine type endopeptidase activityGO:200011780.039
nucleic acid metabolic processGO:00903042440.038
nucleic acid templated transcriptionGO:00976591810.038
heart loopingGO:0001947940.038
blood vessel developmentGO:00015682460.038
cell deathGO:00082191210.038
regulation of alternative mrna splicing via spliceosomeGO:000038110.038
epithelial tube morphogenesisGO:00605621480.037
transcription from rna polymerase ii promoterGO:0006366800.037
positive regulation of neural precursor cell proliferationGO:200017910.037
neuron fate determinationGO:004866420.037
positive regulation of cellular processGO:00485222010.037
synaptic transmissionGO:0007268350.037
extracellular structure organizationGO:0043062270.036
cellular nitrogen compound metabolic processGO:00346412900.036
female sex differentiationGO:004666040.036
peripheral nervous system developmentGO:0007422550.036
cell recognitionGO:0008037190.035
regulation of nervous system developmentGO:0051960900.035
gastrulationGO:00073692080.034
regulation of cellular ketone metabolic processGO:001056570.034
regulation of reproductive processGO:200024140.034
regulation of cell deathGO:00109411030.034
homeostatic processGO:00425921420.033
extracellular matrix assemblyGO:008502910.033
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.033
catecholamine biosynthetic processGO:004242320.033
multi organism reproductive processGO:0044703360.032
defense responseGO:0006952470.031
Mouse
negative regulation of gene expressionGO:0010629650.031
developmental pigmentationGO:0048066480.031
tube morphogenesisGO:00352393490.031
camera type eye morphogenesisGO:00485931080.030
striated muscle tissue developmentGO:00147061100.030
neuron neuron synaptic transmissionGO:000727010.030
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.030
organic anion transportGO:0015711150.030
cell matrix adhesionGO:000716040.029
digestive system developmentGO:00551232890.029
cell projection assemblyGO:0030031640.029
Zebrafish
nucleobase containing compound biosynthetic processGO:00346542050.029
negative regulation of cell motilityGO:2000146170.029
endodermal cell fate determinationGO:000749320.029
cellular component morphogenesisGO:00329893360.028
regulation of axon extensionGO:0030516240.028
regulation of axonogenesisGO:0050770320.028
semicircular canal developmentGO:0060872240.028
cell substrate adhesionGO:003158940.028
chondrocyte intercalation involved in growth plate cartilage morphogenesisGO:000342810.028
response to growth factorGO:0070848390.028
neuroblast proliferationGO:000740520.028
neuron fate specificationGO:0048665200.027
cellular ketone metabolic processGO:0042180110.027
positive regulation of transcription dna templatedGO:0045893570.027
positive regulation of cell differentiationGO:0045597300.027
positive regulation of multicellular organismal processGO:0051240520.027
skeletal system morphogenesisGO:00487051020.026
positive regulation of cell proliferationGO:0008284150.026
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.026
cell maturationGO:0048469230.026
Mouse
extrinsic apoptotic signaling pathwayGO:009719130.026
amino acid transportGO:000686520.026
proximal distal pattern formationGO:000995410.026
g1 s transition of mitotic cell cycleGO:000008210.026
cranial nerve developmentGO:0021545420.025
response to endogenous stimulusGO:0009719830.025
regulation of histone methylationGO:003106030.025
transmembrane transportGO:00550851200.025
positive regulation of glial cell proliferationGO:006025210.025
heart developmentGO:00075073130.025
central nervous system neuron axonogenesisGO:0021955180.024
negative regulation of cell differentiationGO:0045596460.024
negative regulation of programmed cell deathGO:0043069580.024
transcription dna templatedGO:00063511810.024
oocyte maturationGO:000155640.024
regulation of anatomical structure morphogenesisGO:00226031300.024
signal transductionGO:00071654550.024
cellular response to transforming growth factor beta stimulusGO:007156070.023
positive regulation of nucleic acid templated transcriptionGO:1903508570.023
regulation of cell morphogenesis involved in differentiationGO:0010769380.023
negative regulation of epithelial cell migrationGO:001063310.023
organonitrogen compound biosynthetic processGO:1901566470.022
positive regulation of transportGO:005105020.022
alternative mrna splicing via spliceosomeGO:000038010.022
regulation of inner ear receptor cell differentiationGO:200098010.022
developmental growth involved in morphogenesisGO:0060560860.022
peptide metabolic processGO:000651810.022
angiogenesisGO:00015251580.022
multicellular organism reproductionGO:0032504350.022
determination of heart left right asymmetryGO:00613711170.022
negative regulation of biosynthetic processGO:0009890550.022
cardiogenic plate morphogenesisGO:000314210.021
central nervous system projection neuron axonogenesisGO:0021952150.021
ion transmembrane transportGO:0034220910.021
negative regulation of protein phosphorylationGO:000193340.021
cellular protein metabolic processGO:00442671290.021
oxoacid metabolic processGO:0043436310.021
Mouse
skeletal muscle tissue developmentGO:0007519670.021
auditory receptor cell fate determinationGO:004266820.021
glial cell fate commitmentGO:002178160.021
regulation of glucose transportGO:001082710.021
positive regulation of macromolecule biosynthetic processGO:0010557590.021
meiotic nuclear divisionGO:000712640.021
positive regulation of cellular amino acid metabolic processGO:004576400.021
response to axon injuryGO:0048678140.021
regulation of dendrite developmentGO:005077330.021
ventral spinal cord interneuron differentiationGO:0021514120.020
multicellular organism growthGO:003526440.020
wnt signaling pathway planar cell polarity pathwayGO:006007140.020
axial mesodermal cell fate specificationGO:004832730.020
embryonic heart tube morphogenesisGO:00031431080.020
positive regulation of nitrogen compound metabolic processGO:0051173690.020
midbrain developmentGO:0030901280.020
Human
macromolecule modificationGO:00434121110.020
multicellular organismal reproductive processGO:0048609350.020
amine metabolic processGO:000930820.019
epithelial tube formationGO:0072175190.019
axonal fasciculationGO:0007413110.019
glial cell fate determinationGO:000740310.019
positive regulation of endothelial cell differentiationGO:004560320.019
post embryonic organ developmentGO:004856940.018
macromolecule biosynthetic processGO:00090592270.018
negative regulation of cellular protein metabolic processGO:0032269160.018
erythrocyte developmentGO:0048821240.018
startle responseGO:000196440.018
organelle organizationGO:00069962270.018
sensory perception of light stimulusGO:0050953190.018
regulation of multicellular organism growthGO:004001440.018
positive regulation of response to stimulusGO:0048584800.018
sodium ion transmembrane transportGO:0035725210.018
trabecula morphogenesisGO:006138320.017
melanin metabolic processGO:000658220.017
bone developmentGO:0060348140.017
positive regulation of lipid metabolic processGO:004583410.017
positive regulation of erk1 and erk2 cascadeGO:007037420.017
morphogenesis of embryonic epitheliumGO:0016331300.017
periodic partitioningGO:000736510.017
synaptic transmission cholinergicGO:000727140.017
cognitionGO:005089010.017
primary neural tube formationGO:001402010.017
negative regulation of signal transduction in absence of ligandGO:190109910.017
epithelial to mesenchymal transitionGO:0001837210.017
embryonic skeletal system developmentGO:0048706970.017
circulatory system processGO:0003013870.017
positive regulation of mrna metabolic processGO:190331320.016
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.016
extracellular matrix organizationGO:0030198270.016
response to alkaloidGO:004327920.016
single organism transportGO:00447652060.016
bone remodelingGO:004684920.016
erk1 and erk2 cascadeGO:007037140.016
exocrine system developmentGO:0035272280.016
developmental programmed cell deathGO:001062340.016
glial cell differentiationGO:0010001420.016
Mouse
angioblast cell migrationGO:003547690.016
regulation of transcription from rna polymerase ii promoterGO:00063571140.016
stem cell developmentGO:0048864820.016
negative regulation of axon extensionGO:003051770.016
neural crest cell migrationGO:0001755420.015
heart morphogenesisGO:00030071560.015
reproductive processGO:0022414400.015
regulation of mrna splicing via spliceosomeGO:004802430.015
cellular nitrogen compound biosynthetic processGO:00442712180.015
negative regulation of axon regenerationGO:004868140.015
ectoderm developmentGO:000739890.015
organelle assemblyGO:00709251100.015
neural precursor cell proliferationGO:0061351200.015
regulation of neuron projection developmentGO:0010975400.015
regulation of glucose importGO:004632410.015
adult behaviorGO:003053420.015
mesenchymal cell differentiationGO:0048762870.015
transforming growth factor beta receptor signaling pathwayGO:000717970.015
anterior commissure morphogenesisGO:002196030.015
positive regulation of cell adhesionGO:004578510.014
catechol containing compound biosynthetic processGO:000971320.014
negative regulation of neuron projection developmentGO:001097790.014
signal transduction in absence of ligandGO:003803410.014
positive regulation of rna metabolic processGO:0051254590.014
regulation of apoptotic processGO:0042981980.014
methylationGO:0032259220.014
mitotic g2 m transition checkpointGO:004481830.014
organic cyclic compound metabolic processGO:19013603010.014
neural crest cell developmentGO:0014032620.014
regulation of cell sizeGO:0008361290.014
macromolecule methylationGO:0043414190.014
axon extensionGO:0048675450.014
forebrain developmentGO:0030900960.014
muscle structure developmentGO:00610611960.013
translational initiationGO:000641330.013
cell proliferationGO:0008283800.013
regulation of lipid catabolic processGO:005099420.013
reproductionGO:0000003400.013
specification of symmetryGO:00097992040.013
negative regulation of gliogenesisGO:001401410.013
positive regulation of stem cell proliferationGO:200064810.013
artery morphogenesisGO:0048844140.013
regulation of photoreceptor cell differentiationGO:004653220.013
response to mechanical stimulusGO:0009612240.013
venous endothelial cell migration involved in lymph vessel developmentGO:006085540.013
regulation of cellular amine metabolic processGO:003323800.013
facial nucleus developmentGO:002175470.013
negative regulation of cell developmentGO:0010721260.013
negative regulation of neuron projection regenerationGO:007057140.013
regulation of mrna catabolic processGO:006101330.013
somite developmentGO:0061053960.013
mechanosensory behaviorGO:000763820.013
locomotory behaviorGO:0007626340.013
lens development in camera type eyeGO:0002088220.012
cell fate specification involved in pattern specificationGO:006057330.012
regulation of catalytic activityGO:0050790550.012
regulation of cytokine productionGO:000181730.012
anterior lateral line nerve developmentGO:004890940.012
abducens nucleus developmentGO:002174220.012
anterior lateral line nerve glial cell differentiationGO:004891330.012
establishment of localization in cellGO:0051649770.012
eye morphogenesisGO:00485921440.012
regulation of response to stimulusGO:00485832690.012
regulation of erk1 and erk2 cascadeGO:007037240.012
lens fiber cell morphogenesisGO:007030930.012
monoamine transportGO:001584410.012
cellular amine metabolic processGO:004410620.012
multi organism processGO:00517041340.012
regulation of stem cell proliferationGO:007209120.012
regulation of protein import into nucleusGO:004230620.012
secondary metabolic processGO:001974830.012
ventral spinal cord interneuron specificationGO:002152130.012
intracellular receptor signaling pathwayGO:0030522300.012
positive regulation of neurogenesisGO:0050769240.012
negative regulation of developmental processGO:0051093650.012
regulation of extrinsic apoptotic signaling pathwayGO:200123630.012
bone morphogenesisGO:0060349110.012
negative regulation of neurogenesisGO:0050768200.012
cellular component maintenanceGO:004395430.011
neuron fate commitmentGO:0048663260.011
positive regulation of nucleobase containing compound metabolic processGO:0045935690.011
apoptotic signaling pathwayGO:0097190230.011
protein heterooligomerizationGO:005129110.011
positive regulation of nervous system developmentGO:0051962250.011
cellular component biogenesisGO:00440851780.011
Zebrafish
regulation of cell proliferationGO:0042127370.011
regulation of transcription dna templatedGO:00063552130.011
positive regulation of cellular amine metabolic processGO:003324000.011
regulation of cellular component organizationGO:0051128860.011
Zebrafish
hematopoietic or lymphoid organ developmentGO:00485341910.011
cellular amide metabolic processGO:004360340.011
monosaccharide transportGO:001574960.011
transportGO:00068102200.011
myeloid cell developmentGO:0061515320.011
cellular component assembly involved in morphogenesisGO:00109271070.011
negative regulation of transcription dna templatedGO:0045892450.011
inner ear receptor cell fate commitmentGO:006012040.011
protein modification processGO:00362111000.011
negative regulation of nitrogen compound metabolic processGO:0051172590.011
positive regulation of biosynthetic processGO:0009891680.011
organonitrogen compound metabolic processGO:1901564740.011
positive regulation of cellular metabolic processGO:0031325940.011
establishment of protein localization to organelleGO:007259440.010
stem cell maintenanceGO:001982740.010
response to carbohydrateGO:000974330.010
digestive tract morphogenesisGO:00485462310.010
nuclear importGO:005117030.010
determination of bilateral symmetryGO:00098552040.010
establishment of localizationGO:00512342440.010
keratinocyte differentiationGO:003021600.010
positive regulation of catabolic processGO:000989640.010
small molecule metabolic processGO:0044281770.010
Mouse
single organism metabolic processGO:00447102170.010
Mouse
single organism localizationGO:19025782250.010
long chain fatty acid metabolic processGO:000167610.010
Mouse
distal tubule developmentGO:007201710.010
specification of axis polarityGO:006500140.010
visual perceptionGO:0007601170.010

plp1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.434
Human
brain diseaseDOID:93600.434
Human
nervous system diseaseDOID:86300.434
Human
central nervous system diseaseDOID:33100.434
Human
cerebral degenerationDOID:144300.434
Human
leukodystrophyDOID:1057900.434
Human
cancerDOID:16200.025
disease of cellular proliferationDOID:1456600.025
cardiovascular system diseaseDOID:128700.019
organ system cancerDOID:005068600.014
osteochondrodysplasiaDOID:225600.012
bone diseaseDOID:008000100.012
connective tissue diseaseDOID:6500.012
musculoskeletal system diseaseDOID:1700.012
bone development diseaseDOID:008000600.012