Danio rerio

16 known processes

tshr

thyroid stimulating hormone receptor

tshr biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.158
response to chemicalGO:00422213200.091
ion transportGO:00068111140.090
cellular component assembly involved in morphogenesisGO:00109271070.085
anion transportGO:0006820380.081
inorganic anion transportGO:0015698250.066
response to organic cyclic compoundGO:0014070510.057
multicellular organism growthGO:003526440.057
head developmentGO:00603223030.056
sodium ion transmembrane transportGO:0035725210.054
response to amino acidGO:004320020.054
epithelial tube morphogenesisGO:00605621480.050
response to amineGO:001407510.048
cell part morphogenesisGO:00329902460.048
extrinsic apoptotic signaling pathwayGO:009719130.043
cellular response to chemical stimulusGO:00708871570.043
cellular component movementGO:00069283350.042
transportGO:00068102200.041
monovalent inorganic cation transportGO:0015672420.040
cellular response to lipopolysaccharideGO:007122230.039
autophagyGO:000691440.038
transmembrane transportGO:00550851200.037
response to endogenous stimulusGO:0009719830.036
regulation of circadian rhythmGO:004275240.036
ion transmembrane transportGO:0034220910.036
cation transmembrane transportGO:0098655650.035
agingGO:000756820.035
cellular response to organic substanceGO:00713101050.035
regulation of stem cell differentiationGO:200073640.035
cellular component morphogenesisGO:00329893360.034
signal transductionGO:00071654550.034
sensory organ developmentGO:00074233930.034
synaptic vesicle transportGO:004848910.033
regulation of developmental processGO:00507932470.033
cellular amino acid metabolic processGO:000652070.033
stem cell maintenanceGO:001982740.032
cell motilityGO:00488702440.032
cell projection morphogenesisGO:00488582440.032
establishment of protein localization to plasma membraneGO:009000210.030
epithelial cell morphogenesisGO:000338220.029
cellular response to organic cyclic compoundGO:0071407380.029
response to external biotic stimulusGO:0043207970.029
response to oxygen containing compoundGO:1901700550.029
phagocytosisGO:000690930.029
muscle cell developmentGO:00550011150.029
neuron developmentGO:00486662620.028
female sex differentiationGO:004666040.028
response to alkaloidGO:004327920.028
striated muscle cell developmentGO:00550021080.028
cilium morphogenesisGO:0060271850.028
cytokinesisGO:000091030.028
cellular protein catabolic processGO:004425740.028
cellular component assemblyGO:00226071700.027
cation transportGO:0006812810.027
regulation of cellular amine metabolic processGO:003323800.027
heterocycle metabolic processGO:00464832900.027
growthGO:00400071740.027
maintenance of locationGO:005123540.027
nucleic acid metabolic processGO:00903042440.027
synaptic vesicle localizationGO:009747910.027
nitrogen compound metabolic processGO:00068073190.026
sodium ion transportGO:0006814240.026
inorganic ion transmembrane transportGO:0098660570.026
regulation of cell substrate adhesionGO:001081010.026
cell projection organizationGO:00300302840.026
proteolysis involved in cellular protein catabolic processGO:005160330.026
establishment of synaptic vesicle localizationGO:009748010.026
forebrain developmentGO:0030900960.026
cellular response to external stimulusGO:007149620.026
female gonad developmentGO:000858540.026
morphogenesis of an epitheliumGO:00020093330.026
chordate embryonic developmentGO:00430092710.026
regulation of cellular amino acid metabolic processGO:000652100.026
organelle organizationGO:00069962270.026
digestive tract morphogenesisGO:00485462310.025
cellular response to reactive oxygen speciesGO:003461420.025
regulation of erk1 and erk2 cascadeGO:007037240.025
gtp metabolic processGO:004603940.025
single organism transportGO:00447652060.025
guanosine containing compound metabolic processGO:190106840.025
central nervous system developmentGO:00074173870.025
response to nitrogen compoundGO:1901698190.025
regionalizationGO:00030022740.025
single organism localizationGO:19025782250.025
cellular amine metabolic processGO:004410620.025
cell substrate adhesionGO:003158940.025
mitochondrion organizationGO:000700540.025
cellular component biogenesisGO:00440851780.025
mitotic cytokinesisGO:000028130.024
striated muscle tissue developmentGO:00147061100.024
guanosine containing compound catabolic processGO:190106920.024
protein metabolic processGO:00195381830.024
amine metabolic processGO:000930820.024
locomotionGO:00400113130.024
regulation of nucleoside metabolic processGO:000911820.024
positive regulation of transportGO:005105020.024
neuron differentiationGO:00301823530.024
embryonic organ morphogenesisGO:00485622740.024
positive regulation of blood circulationGO:190352420.024
response to oxidative stressGO:0006979110.023
neurotransmitter transportGO:000683620.023
negative regulation of biological processGO:00485193040.023
response to methanolGO:003398640.023
regulation of establishment of protein localizationGO:007020140.023
cell morphogenesis involved in differentiationGO:00009041950.023
cell morphogenesisGO:00009022890.022
regulation of multicellular organismal processGO:00512392770.022
regulation of cytokine productionGO:000181730.022
positive regulation of cellular catabolic processGO:003133130.022
transcription from rna polymerase ii promoterGO:0006366800.022
fertilizationGO:000956630.022
response to monosaccharideGO:003428430.022
reactive oxygen species biosynthetic processGO:190340910.022
negative regulation of stem cell differentiationGO:200073720.022
cell migrationGO:00164772370.022
cognitionGO:005089010.021
cellular response to endogenous stimulusGO:0071495680.021
endocrine processGO:005088620.021
response to external stimulusGO:00096052640.021
establishment of localizationGO:00512342440.021
protein complex disassemblyGO:004324110.021
regulation of establishment of protein localization to plasma membraneGO:009000310.021
brain developmentGO:00074202930.021
compound eye developmentGO:004874920.021
positive regulation of cytosolic calcium ion concentrationGO:000720440.020
cellular macromolecule metabolic processGO:00442603910.020
regulation of synaptic growth at neuromuscular junctionGO:000858210.020
tube morphogenesisGO:00352393490.020
positive regulation of protein complex assemblyGO:003133420.020
regulation of synapse assemblyGO:005196330.020
modification dependent macromolecule catabolic processGO:004363230.020
oxoacid metabolic processGO:0043436310.020
positive regulation of catabolic processGO:000989640.020
biosynthetic processGO:00090582940.020
cellular modified amino acid metabolic processGO:000657530.020
regulation of neuronal synaptic plasticityGO:004816810.020
neuron neuron synaptic transmissionGO:000727010.020
regulation of protein catabolic processGO:004217610.020
membrane fusionGO:006102520.020
nuclear transportGO:005116940.019
protein acetylationGO:000647320.019
gtp catabolic processGO:000618420.019
organelle fusionGO:004828430.019
response to organic substanceGO:00100331530.019
organonitrogen compound metabolic processGO:1901564740.019
response to hexoseGO:000974630.019
single organism organelle organizationGO:19025891990.019
response to carbohydrateGO:000974330.019
response to bacteriumGO:0009617580.019
protein localization to nucleusGO:003450430.019
regulation of multicellular organismal developmentGO:20000262230.019
heart contractionGO:0060047710.019
somatic stem cell maintenanceGO:003501910.019
positive regulation of cellular amino acid metabolic processGO:004576400.019
hematopoietic or lymphoid organ developmentGO:00485341910.019
peptidyl lysine acetylationGO:001839420.019
nuclear importGO:005117030.018
regulation of synaptic plasticityGO:004816710.018
regulation of cellular metabolic processGO:00313233200.018
regulation of gene expressionGO:00104682650.018
regulation of biological qualityGO:00650082630.018
positive regulation of myeloid cell differentiationGO:004563920.018
embryonic organ developmentGO:00485683810.018
response to hydrogen peroxideGO:004254230.018
neuronal stem cell maintenanceGO:009715020.018
response to uvGO:000941130.018
positive regulation of cellular amine metabolic processGO:003324000.018
carboxylic acid metabolic processGO:0019752220.018
organelle assemblyGO:00709251100.018
embryo development ending in birth or egg hatchingGO:00097922710.018
neuron projection developmentGO:00311751800.017
negative regulation of cellular processGO:00485232830.017
meiotic nuclear divisionGO:000712640.017
nucleobase containing compound metabolic processGO:00061392740.017
adult behaviorGO:003053420.017
immune system processGO:00023762410.017
organic acid metabolic processGO:0006082310.017
reactive oxygen species metabolic processGO:007259360.017
adherens junction organizationGO:003433240.017
negative regulation of catabolic processGO:000989530.017
regulation of bindingGO:005109830.017
synaptic growth at neuromuscular junctionGO:005112420.017
muscle structure developmentGO:00610611960.017
response to amphetamineGO:000197510.017
establishment of protein localization to organelleGO:007259440.017
regulation of signalingGO:00230512350.017
membrane lipid biosynthetic processGO:004646720.017
nucleocytoplasmic transportGO:000691340.016
regulation of dendrite developmentGO:005077330.016
axonogenesisGO:00074091520.016
protein acylationGO:004354330.016
somatic muscle developmentGO:000752540.016
cellular response to starvationGO:000926710.016
protein localization to plasma membraneGO:007265910.016
cilium assemblyGO:0042384580.016
exocytosisGO:000688710.016
cellular aromatic compound metabolic processGO:00067252950.016
meiotic cell cycle processGO:190304630.016
positive regulation of cell deathGO:0010942290.016
regulation of nitrogen compound metabolic processGO:00511712510.016
mesenchyme developmentGO:00604851270.016
regulation of neurotransmitter transportGO:005158810.016
cellular response to methanolGO:007140540.016
regulation of cytoplasmic transportGO:190364940.016
positive regulation of gtpase activityGO:004354710.016
regulation of synapse organizationGO:005080730.016
cellular response to hormone stimulusGO:0032870390.016
blood vessel developmentGO:00015682460.016
determination of bilateral symmetryGO:00098552040.016
metal ion transportGO:0030001580.016
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.016
connective tissue developmentGO:0061448990.016
regulation of peptidyl tyrosine phosphorylationGO:005073010.016
regulation of dendrite morphogenesisGO:004881430.016
regulation of reactive oxygen species metabolic processGO:200037720.016
organic cyclic compound metabolic processGO:19013603010.016
rna metabolic processGO:00160702190.016
glial cell proliferationGO:001400940.015
actin filament based movementGO:003004810.015
positive regulation of cell cycleGO:004578730.015
muscle cell differentiationGO:00426921390.015
regulation of extrinsic apoptotic signaling pathwayGO:200123630.015
cellular protein metabolic processGO:00442671290.015
single organism metabolic processGO:00447102170.015
regulation of intracellular protein transportGO:003315730.015
regulation of i kappab kinase nf kappab signalingGO:004312240.015
regulation of blood vessel sizeGO:005088020.015
b cell activationGO:004211320.015
peptide transportGO:001583310.015
cilium organizationGO:0044782710.015
endocrine system developmentGO:0035270650.015
regulation of nucleotide catabolic processGO:003081120.015
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.015
cytoskeleton dependent cytokinesisGO:006164030.015
erk1 and erk2 cascadeGO:007037140.015
gastrulationGO:00073692080.015
response to stressGO:00069502630.015
mitochondrial transportGO:000683920.015
signal transduction in absence of ligandGO:003803410.015
membrane invaginationGO:001032410.015
localization of cellGO:00516742440.015
regulation of cellular ketone metabolic processGO:001056570.015
stem cell proliferationGO:007208940.015
leukocyte proliferationGO:007066110.015
positive regulation of cytoskeleton organizationGO:005149530.015
regulation of purine nucleotide catabolic processGO:003312120.015
regulation of reproductive processGO:200024140.015
proteasomal protein catabolic processGO:001049820.015
response to woundingGO:00096111160.015
regulation of gtpase activityGO:004308720.014
gland developmentGO:00487321430.014
golgi vesicle transportGO:004819330.014
meiotic chromosome segregationGO:004513230.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
olfactory bulb developmentGO:002177240.014
regulation of cell activationGO:005086510.014
glucose homeostasisGO:004259310.014
regulation of blood pressureGO:000821710.014
modification dependent protein catabolic processGO:001994130.014
cell matrix adhesionGO:000716040.014
regulation of stem cell proliferationGO:007209120.014
phagocytosis engulfmentGO:000691110.014
hydrogen peroxide metabolic processGO:004274320.014
immune system developmentGO:00025201910.014
internal protein amino acid acetylationGO:000647520.014
post embryonic morphogenesisGO:000988640.014
determination of left right symmetryGO:00073681790.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
regulation of gtp catabolic processGO:003312420.014
cellular component disassemblyGO:002241110.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.014
carbohydrate homeostasisGO:003350010.014
positive regulation of nucleoside metabolic processGO:004597910.014
internal peptidyl lysine acetylationGO:001839320.014
regulation of systemic arterial blood pressureGO:000307310.014
ear developmentGO:00435831270.014
regulation of response to stimulusGO:00485832690.014
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.014
regulation of inflammatory responseGO:005072720.014
regulation of cell deathGO:00109411030.014
cellular response to extracellular stimulusGO:003166820.014
lateral inhibitionGO:004633110.014
positive regulation of cellular component biogenesisGO:004408930.014
regulation of mrna processingGO:005068430.014
hormone secretionGO:004687920.013
positive regulation of epithelial cell differentiationGO:003085820.013
germ line stem cell maintenanceGO:003071820.013
locomotor rhythmGO:004547530.013
cell surface receptor signaling pathwayGO:00071663250.013
regulation of apoptotic processGO:0042981980.013
response to hormoneGO:0009725480.013
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
ubiquitin dependent protein catabolic processGO:000651130.013
camera type eye developmentGO:00430102220.013
cell projection assemblyGO:0030031640.013
neuron projection morphogenesisGO:00488121610.013
lipid storageGO:001991510.013
i kappab kinase nf kappab signalingGO:000724940.013
glial cell migrationGO:000834730.013
somite developmentGO:0061053960.013
mitotic dna integrity checkpointGO:004477440.013
tissue remodelingGO:004877140.013
defense response to fungusGO:005083220.013
digestive tract developmentGO:00485652650.013
multi organism processGO:00517041340.013
regulation of epithelial cell proliferationGO:005067830.013
cellular macromolecule biosynthetic processGO:00346452240.013
regulation of multicellular organism growthGO:004001440.013
regulation of protein transportGO:005122330.013
stem cell differentiationGO:00488631170.013
macromolecular complex disassemblyGO:003298410.013
regulation of cellular protein catabolic processGO:190336210.013
embryonic skeletal system morphogenesisGO:0048704930.013
regulation of metabolic processGO:00192223590.013
regulation of signal transductionGO:00099662250.013
b cell differentiationGO:003018310.013
lymphocyte proliferationGO:004665110.013
actin polymerization or depolymerizationGO:000815420.013
negative regulation of protein phosphorylationGO:000193340.013
response to topologically incorrect proteinGO:003596620.013
regulation of cell shapeGO:000836010.013
regulation of neurogenesisGO:0050767870.013
anterior posterior pattern specificationGO:00099521520.013
multi organism cellular processGO:004476420.013
system processGO:00030081850.013
organic cyclic compound biosynthetic processGO:19013622230.013
gene expressionGO:00104672520.013
sleepGO:003043110.013
nephron morphogenesisGO:007202820.013
single organism nuclear importGO:190259330.013
interspecies interaction between organismsGO:004441940.013
cell killingGO:000190620.012
synaptic vesicle endocytosisGO:004848810.012
hormone transportGO:000991420.012
cellular ketone metabolic processGO:0042180110.012
regulation of cellular biosynthetic processGO:00313262450.012
cytoplasm organizationGO:000702840.012
protein targeting to nucleusGO:004474430.012
regulation of nucleocytoplasmic transportGO:004682220.012
embryonic cranial skeleton morphogenesisGO:0048701900.012
regulation of protein complex assemblyGO:004325430.012
pigment granule localizationGO:0051875250.012
regulation of transmembrane transporter activityGO:002289820.012
regulation of ion transmembrane transporter activityGO:003241220.012
reflexGO:006000420.012
regulation of cell differentiationGO:00455951420.012
phosphatidylinositol 3 kinase signalingGO:001406520.012
mononuclear cell proliferationGO:003294310.012
negative regulation of sequestering of calcium ionGO:005128340.012
positive regulation of gtp catabolic processGO:003312610.012
generation of neuronsGO:00486993850.012
inner ear developmentGO:00488391260.012
rna localizationGO:000640340.012
specification of symmetryGO:00097992040.012
axon developmentGO:00615641660.012
response to other organismGO:0051707970.012
regulation of transcription from rna polymerase ii promoterGO:00063571140.012
regulation of cell communicationGO:00106462320.012
regulation of cell projection assemblyGO:006049140.012
regulation of phGO:000688530.012
organic anion transportGO:0015711150.012
skeletal system morphogenesisGO:00487051020.012
dorsal ventral pattern formationGO:00099531250.012
mesenchymal cell developmentGO:0014031780.012
production of molecular mediator of immune responseGO:000244020.012
regulation of macromolecule metabolic processGO:00602553170.012
symbiosis encompassing mutualism through parasitismGO:004440340.012
monocarboxylic acid transportGO:001571850.012
atp catabolic processGO:000620040.012
carboxylic acid transportGO:004694280.012
positive regulation of nucleotide catabolic processGO:003081310.012
skeletal system developmentGO:00015011810.012
mitochondrion morphogenesisGO:007058420.012
stem cell developmentGO:0048864820.012
mesenchymal cell differentiationGO:0048762870.012
embryonic skeletal system developmentGO:0048706970.012
monoamine transportGO:001584410.012
protein polymerizationGO:005125840.012
olfactory lobe developmentGO:002198840.012
sequestering of metal ionGO:005123830.012
outflow tract morphogenesisGO:000315110.012
organic acid transportGO:001584990.012
negative regulation of kinase activityGO:003367340.012
regulation of glial cell differentiationGO:004568540.012
smooth muscle contractionGO:000693920.012
positive regulation of heart contractionGO:004582320.012
rna biosynthetic processGO:00327741810.012
cellular response to molecule of bacterial originGO:007121930.012
myeloid cell differentiationGO:0030099860.012
positive regulation of protein polymerizationGO:003227320.011
positive regulation of cytokine productionGO:000181920.011
secondary metabolic processGO:001974830.011
wound healingGO:0042060900.011
protein import into nucleusGO:000660630.011
actin mediated cell contractionGO:007025210.011
nucleobase containing compound biosynthetic processGO:00346542050.011
hatching gland developmentGO:004878530.011
neural crest cell differentiationGO:0014033720.011
regulation of jak stat cascadeGO:004642530.011
positive regulation of dna metabolic processGO:005105410.011
purine ribonucleoside monophosphate catabolic processGO:000916940.011
heart developmentGO:00075073130.011
regulation of rna metabolic processGO:00512522240.011
regulation of protein depolymerizationGO:190187910.011
striated muscle cell differentiationGO:00511461290.011
carbohydrate biosynthetic processGO:001605110.011
positive regulation of secretionGO:005104710.011
regulation of wound healingGO:006104120.011
histone h3 k4 methylationGO:005156820.011
post embryonic organ developmentGO:004856940.011
hormone metabolic processGO:0042445190.011
developmental growth involved in morphogenesisGO:0060560860.011
small molecule metabolic processGO:0044281770.011
regulation of organ growthGO:004662030.011
heterocycle biosynthetic processGO:00181302150.011
ovulation cycle processGO:002260220.011
regulation of protein ubiquitinationGO:003139630.011
regulation of meiotic cell cycleGO:005144510.011
nucleic acid templated transcriptionGO:00976591810.011
positive regulation of purine nucleotide catabolic processGO:003312310.011
heart morphogenesisGO:00030071560.011
neurotransmitter secretionGO:000726920.011
cell deathGO:00082191210.011
ovarian follicle developmentGO:000154120.011
actin filament based processGO:0030029640.011
embryonic viscerocranium morphogenesisGO:0048703520.011
regulation of autophagyGO:001050630.011
blood circulationGO:0008015870.011
positive regulation of synapse assemblyGO:005196510.011
regulation of cellular phGO:003064110.011
positive regulation of cell adhesionGO:004578510.011
negative regulation of cellular catabolic processGO:003133030.011
cellular nitrogen compound biosynthetic processGO:00442712180.011
positive regulation of histone modificationGO:003105810.011
macromolecule modificationGO:00434121110.011
neuromuscular process controlling balanceGO:005088530.011
inositol lipid mediated signalingGO:004801720.011
digestive system developmentGO:00551232890.011
development of primary female sexual characteristicsGO:004654540.011
synaptic transmission cholinergicGO:000727140.011
synaptic target recognitionGO:000803910.011
cellular protein complex disassemblyGO:004362410.011
embryonic pattern specificationGO:0009880440.011
single organism membrane fusionGO:004480120.011
sensory perception of painGO:001923310.011
eye developmentGO:00016542770.011
positive regulation of i kappab kinase nf kappab signalingGO:004312330.010
adherens junction assemblyGO:003433310.010
protein depolymerizationGO:005126110.010
lymphangiogenesisGO:0001946250.010
regulation of neurotransmitter secretionGO:004692810.010
positive regulation of nitrogen compound metabolic processGO:0051173690.010
cellular pigmentationGO:0033059300.010
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.010
entrainment of circadian clockGO:000964920.010
negative regulation of mapk cascadeGO:004340940.010
positive regulation of stem cell proliferationGO:200064810.010
vesicle localizationGO:0051648270.010
negative regulation of protein transportGO:005122430.010
polarized epithelial cell differentiationGO:003085940.010
mechanosensory behaviorGO:000763820.010
negative regulation of protein serine threonine kinase activityGO:007190120.010
protein homooligomerizationGO:005126030.010
leukocyte mediated cytotoxicityGO:000190910.010
neuromuscular synaptic transmissionGO:000727420.010
regulation of protein import into nucleusGO:004230620.010
protein modification processGO:00362111000.010
antimicrobial humoral responseGO:001973020.010
protein importGO:001703830.010
positive regulation of immune effector processGO:000269930.010
nucleoside monophosphate catabolic processGO:000912540.010
lamellipodium organizationGO:009758110.010
apoptotic processGO:00069151160.010
viral processGO:001603210.010
modulation by virus of host morphology or physiologyGO:001904810.010
central nervous system neuron differentiationGO:0021953740.010
regulation of macromolecule biosynthetic processGO:00105562250.010
negative regulation of mitosisGO:004583930.010
regulation of transporter activityGO:003240920.010
deathGO:00162651210.010
notochord developmentGO:0030903540.010

tshr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.120
endocrine system diseaseDOID:2800.040
hypothyroidismDOID:145900.040
thyroid gland diseaseDOID:5000.040
cardiovascular system diseaseDOID:128700.020
disease of cellular proliferationDOID:1456600.017
cancerDOID:16200.017
organ system cancerDOID:005068600.017
immune system diseaseDOID:291400.015
hematopoietic system diseaseDOID:7400.011