| cellular response to topologically incorrect protein | GO:0035967 | 2 | 0.906 | Worm |
| endoplasmic reticulum unfolded protein response | GO:0030968 | 2 | 0.776 | Worm |
| response to topologically incorrect protein | GO:0035966 | 2 | 0.734 | Worm |
| response to unfolded protein | GO:0006986 | 2 | 0.581 | Worm |
| response to endoplasmic reticulum stress | GO:0034976 | 6 | 0.574 | Worm |
| cellular protein catabolic process | GO:0044257 | 4 | 0.491 | Mouse |
| cellular response to unfolded protein | GO:0034620 | 2 | 0.472 | Worm |
| er nucleus signaling pathway | GO:0006984 | 2 | 0.402 | Worm |
| aging | GO:0007568 | 2 | 0.375 | |
| proteasomal protein catabolic process | GO:0010498 | 2 | 0.322 | |
| modification dependent protein catabolic process | GO:0019941 | 3 | 0.297 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 3 | 0.240 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 2 | 0.202 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 3 | 0.162 | |
| larval development | GO:0002164 | 2 | 0.135 | |
| cellular macromolecule metabolic process | GO:0044260 | 391 | 0.126 | Mouse |
| positive regulation of secretion by cell | GO:1903532 | 1 | 0.126 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 3 | 0.096 | Mouse |
| response to chemical | GO:0042221 | 320 | 0.096 | Worm |
| cell substrate junction assembly | GO:0007044 | 2 | 0.086 | |
| signal transduction | GO:0007165 | 455 | 0.082 | Worm |
| proteolysis | GO:0006508 | 38 | 0.076 | Mouse |
| hormone transport | GO:0009914 | 2 | 0.075 | |
| embryonic organ development | GO:0048568 | 381 | 0.070 | |
| response to stress | GO:0006950 | 263 | 0.069 | Worm |
| transmembrane transport | GO:0055085 | 120 | 0.069 | |
| multicellular organism growth | GO:0035264 | 4 | 0.065 | |
| hormone secretion | GO:0046879 | 2 | 0.065 | |
| cellular protein metabolic process | GO:0044267 | 129 | 0.064 | Mouse |
| regulation of multicellular organism growth | GO:0040014 | 4 | 0.060 | |
| cellular response to chemical stimulus | GO:0070887 | 157 | 0.058 | Worm |
| single organism localization | GO:1902578 | 225 | 0.055 | |
| protein metabolic process | GO:0019538 | 183 | 0.054 | Mouse |
| lipid storage | GO:0019915 | 1 | 0.053 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 1 | 0.051 | |
| protein import | GO:0017038 | 3 | 0.047 | |
| response to heat | GO:0009408 | 6 | 0.042 | |
| cellular response to stress | GO:0033554 | 62 | 0.040 | Worm |
| central nervous system development | GO:0007417 | 387 | 0.040 | |
| locomotion | GO:0040011 | 313 | 0.038 | |
| positive regulation of transport | GO:0051050 | 2 | 0.038 | |
| amine metabolic process | GO:0009308 | 2 | 0.037 | |
| regulation of blood pressure | GO:0008217 | 1 | 0.037 | |
| cell morphogenesis | GO:0000902 | 289 | 0.037 | |
| cell death | GO:0008219 | 121 | 0.034 | |
| maintenance of location | GO:0051235 | 4 | 0.034 | |
| regulation of blood vessel size | GO:0050880 | 2 | 0.034 | |
| response to antibiotic | GO:0046677 | 1 | 0.034 | |
| regulation of hormone secretion | GO:0046883 | 2 | 0.034 | |
| neuron differentiation | GO:0030182 | 353 | 0.034 | |
| neuron projection development | GO:0031175 | 180 | 0.033 | |
| establishment of protein localization to organelle | GO:0072594 | 4 | 0.033 | |
| regulation of cytokine production | GO:0001817 | 3 | 0.032 | |
| protein n linked glycosylation | GO:0006487 | 1 | 0.031 | |
| regulation of cellular amine metabolic process | GO:0033238 | 0 | 0.030 | |
| chordate embryonic development | GO:0043009 | 271 | 0.030 | |
| response to abiotic stimulus | GO:0009628 | 122 | 0.030 | |
| regulation of apoptotic process | GO:0042981 | 98 | 0.029 | |
| cellular response to organic substance | GO:0071310 | 105 | 0.029 | Worm |
| regulation of cell activation | GO:0050865 | 1 | 0.029 | |
| cellular amine metabolic process | GO:0044106 | 2 | 0.028 | |
| cellular biosynthetic process | GO:0044249 | 286 | 0.028 | |
| regulation of signaling | GO:0023051 | 235 | 0.027 | |
| regulation of signal transduction | GO:0009966 | 225 | 0.027 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 0 | 0.027 | |
| regulation of programmed cell death | GO:0043067 | 101 | 0.027 | |
| regulation of response to stimulus | GO:0048583 | 269 | 0.027 | |
| death | GO:0016265 | 121 | 0.027 | |
| regulation of tube size | GO:0035150 | 2 | 0.026 | |
| multicellular organismal metabolic process | GO:0044236 | 2 | 0.025 | |
| peptide transport | GO:0015833 | 1 | 0.025 | |
| toxin transport | GO:1901998 | 2 | 0.025 | |
| positive regulation of cytokine production | GO:0001819 | 2 | 0.025 | |
| macromolecule biosynthetic process | GO:0009059 | 227 | 0.025 | |
| brain development | GO:0007420 | 293 | 0.025 | |
| regulation of organ growth | GO:0046620 | 3 | 0.024 | |
| positive regulation of secretion | GO:0051047 | 1 | 0.024 | |
| cellular response to biotic stimulus | GO:0071216 | 3 | 0.024 | |
| regulation of biological quality | GO:0065008 | 263 | 0.024 | |
| response to external biotic stimulus | GO:0043207 | 97 | 0.024 | |
| cellular component morphogenesis | GO:0032989 | 336 | 0.023 | |
| cellular ketone metabolic process | GO:0042180 | 11 | 0.022 | |
| positive regulation of translation | GO:0045727 | 1 | 0.022 | |
| positive regulation of nuclease activity | GO:0032075 | 1 | 0.022 | |
| response to biotic stimulus | GO:0009607 | 97 | 0.022 | |
| head development | GO:0060322 | 303 | 0.022 | |
| negative regulation of cellular catabolic process | GO:0031330 | 3 | 0.022 | |
| developmental growth | GO:0048589 | 166 | 0.021 | |
| negative regulation of cell death | GO:0060548 | 60 | 0.021 | |
| programmed cell death | GO:0012501 | 119 | 0.021 | |
| response to steroid hormone | GO:0048545 | 35 | 0.020 | |
| cellular protein modification process | GO:0006464 | 100 | 0.020 | |
| response to temperature stimulus | GO:0009266 | 15 | 0.020 | |
| single organism carbohydrate metabolic process | GO:0044723 | 12 | 0.020 | |
| regulation of protein transport | GO:0051223 | 3 | 0.020 | |
| regulation of binding | GO:0051098 | 3 | 0.020 | |
| hindbrain development | GO:0030902 | 91 | 0.020 | |
| skeletal system development | GO:0001501 | 181 | 0.019 | |
| regulation of multicellular organismal process | GO:0051239 | 277 | 0.019 | |
| regulation of localization | GO:0032879 | 104 | 0.019 | |
| protein modification by small protein removal | GO:0070646 | 1 | 0.018 | |
| cation transmembrane transport | GO:0098655 | 65 | 0.018 | |
| positive regulation of cell activation | GO:0050867 | 1 | 0.018 | |
| cell surface receptor signaling pathway | GO:0007166 | 325 | 0.018 | |
| cell fate commitment | GO:0045165 | 99 | 0.018 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 106 | 0.018 | |
| intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | GO:0070059 | 3 | 0.018 | |
| symbiosis encompassing mutualism through parasitism | GO:0044403 | 4 | 0.018 | |
| regulation of transporter activity | GO:0032409 | 2 | 0.018 | |
| membrane lipid biosynthetic process | GO:0046467 | 2 | 0.018 | |
| inositol lipid mediated signaling | GO:0048017 | 2 | 0.018 | |
| regulation of systemic arterial blood pressure | GO:0003073 | 1 | 0.018 | |
| ion transport | GO:0006811 | 114 | 0.017 | |
| endodermal digestive tract morphogenesis | GO:0061031 | 2 | 0.017 | |
| carbohydrate homeostasis | GO:0033500 | 1 | 0.017 | |
| regulation of cell death | GO:0010941 | 103 | 0.017 | |
| cellular response to toxic substance | GO:0097237 | 1 | 0.017 | |
| organic substance biosynthetic process | GO:1901576 | 289 | 0.017 | |
| biosynthetic process | GO:0009058 | 294 | 0.017 | |
| response to estrogen | GO:0043627 | 27 | 0.017 | |
| sphingolipid biosynthetic process | GO:0030148 | 2 | 0.017 | |
| golgi vesicle transport | GO:0048193 | 3 | 0.016 | |
| regulation of protein catabolic process | GO:0042176 | 1 | 0.016 | |
| protein glycosylation | GO:0006486 | 9 | 0.016 | |
| negative regulation of cellular process | GO:0048523 | 283 | 0.016 | |
| phosphatidylinositol 3 kinase signaling | GO:0014065 | 2 | 0.016 | |
| embryonic skeletal system morphogenesis | GO:0048704 | 93 | 0.016 | |
| system process | GO:0003008 | 185 | 0.016 | |
| exocrine pancreas development | GO:0031017 | 28 | 0.016 | |
| water homeostasis | GO:0030104 | 4 | 0.016 | |
| regulation of metal ion transport | GO:0010959 | 4 | 0.016 | |
| cellular response to antibiotic | GO:0071236 | 1 | 0.015 | |
| cellular macromolecule catabolic process | GO:0044265 | 12 | 0.015 | Mouse |
| response to external stimulus | GO:0009605 | 264 | 0.015 | |
| negative regulation of signaling | GO:0023057 | 96 | 0.015 | |
| protein secretion | GO:0009306 | 1 | 0.014 | |
| embryonic cranial skeleton morphogenesis | GO:0048701 | 90 | 0.014 | |
| growth | GO:0040007 | 174 | 0.014 | |
| response to organic substance | GO:0010033 | 153 | 0.014 | Worm |
| protein modification process | GO:0036211 | 100 | 0.014 | |
| hepatocyte proliferation | GO:0072574 | 2 | 0.014 | |
| neuron development | GO:0048666 | 262 | 0.014 | |
| negative regulation of protein kinase activity | GO:0006469 | 4 | 0.014 | |
| protein targeting to membrane | GO:0006612 | 1 | 0.014 | |
| regulation of cell communication | GO:0010646 | 232 | 0.014 | |
| multicellular organismal macromolecule metabolic process | GO:0044259 | 2 | 0.013 | |
| renal absorption | GO:0070293 | 1 | 0.013 | |
| b cell activation | GO:0042113 | 2 | 0.013 | |
| regulation of neurotransmitter secretion | GO:0046928 | 1 | 0.013 | |
| collagen metabolic process | GO:0032963 | 2 | 0.013 | |
| lateral inhibition | GO:0046331 | 1 | 0.013 | |
| positive regulation of multicellular organismal process | GO:0051240 | 52 | 0.013 | |
| mesenchyme development | GO:0060485 | 127 | 0.013 | |
| iron ion transmembrane transport | GO:0034755 | 3 | 0.013 | |
| collagen biosynthetic process | GO:0032964 | 2 | 0.013 | |
| negative regulation of catabolic process | GO:0009895 | 3 | 0.012 | |
| establishment of localization | GO:0051234 | 244 | 0.012 | |
| cellular macromolecule biosynthetic process | GO:0034645 | 224 | 0.012 | |
| response to amino acid | GO:0043200 | 2 | 0.012 | |
| glucose homeostasis | GO:0042593 | 1 | 0.012 | |
| myeloid cell differentiation | GO:0030099 | 86 | 0.012 | |
| cellular response to nutrient levels | GO:0031669 | 2 | 0.012 | |
| inorganic ion transmembrane transport | GO:0098660 | 57 | 0.012 | |
| fatty acid catabolic process | GO:0009062 | 1 | 0.012 | |
| regulation of epithelial cell proliferation | GO:0050678 | 3 | 0.012 | |
| negative regulation of protein phosphorylation | GO:0001933 | 4 | 0.012 | |
| regulation of blood coagulation | GO:0030193 | 1 | 0.012 | |
| positive regulation of embryonic development | GO:0040019 | 3 | 0.012 | |
| cellular response to estrogen stimulus | GO:0071391 | 24 | 0.012 | |
| positive regulation of catabolic process | GO:0009896 | 4 | 0.012 | |
| response to decreased oxygen levels | GO:0036293 | 25 | 0.012 | |
| negative regulation of defense response | GO:0031348 | 2 | 0.011 | |
| regulation of production of molecular mediator of immune response | GO:0002700 | 1 | 0.011 | |
| glycoprotein metabolic process | GO:0009100 | 23 | 0.011 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 7 | 0.011 | |
| generation of neurons | GO:0048699 | 385 | 0.011 | |
| cellular response to organic cyclic compound | GO:0071407 | 38 | 0.011 | |
| apoptotic process | GO:0006915 | 116 | 0.011 | |
| oligopeptide transport | GO:0006857 | 1 | 0.011 | |
| positive regulation of extrinsic apoptotic signaling pathway | GO:2001238 | 1 | 0.011 | |
| neurotransmitter transport | GO:0006836 | 2 | 0.011 | |
| otolith development | GO:0048840 | 32 | 0.011 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 3 | 0.011 | |
| macromolecule modification | GO:0043412 | 111 | 0.011 | |
| production of molecular mediator of immune response | GO:0002440 | 2 | 0.011 | |
| negative regulation of programmed cell death | GO:0043069 | 58 | 0.011 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 271 | 0.011 | |
| regulation of protein ubiquitination | GO:0031396 | 3 | 0.010 | |
| single organism metabolic process | GO:0044710 | 217 | 0.010 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 3 | 0.010 | |
| regulation of autophagy | GO:0010506 | 3 | 0.010 | |
| negative regulation of multi organism process | GO:0043901 | 3 | 0.010 | |
| response to alkaloid | GO:0043279 | 2 | 0.010 | |
