Danio rerio

14 known processes

otol1a

otolin 1a

(Aliases: zOtolin1,otol1,Gm414,si:dkey-119f1.2)

otol1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryonic organ developmentGO:00485683810.092
sensory organ developmentGO:00074233930.060
embryonic organ morphogenesisGO:00485622740.060
larval developmentGO:000216420.058
morphogenesis of an epitheliumGO:00020093330.041
agingGO:000756820.040
cellular protein catabolic processGO:004425740.038
chordate embryonic developmentGO:00430092710.036
tube morphogenesisGO:00352393490.035
positive regulation of transportGO:005105020.032
phagocytosisGO:000690930.031
cellular component movementGO:00069283350.030
regionalizationGO:00030022740.030
head developmentGO:00603223030.029
biosynthetic processGO:00090582940.029
cellular biosynthetic processGO:00442492860.028
proteolysis involved in cellular protein catabolic processGO:005160330.028
ear developmentGO:00435831270.028
regulation of multicellular organism growthGO:004001440.028
signal transductionGO:00071654550.027
skeletal system developmentGO:00015011810.027
cell surface receptor signaling pathwayGO:00071663250.027
embryonic skeletal system developmentGO:0048706970.027
eye developmentGO:00016542770.027
organic substance biosynthetic processGO:19015762890.027
multicellular organism growthGO:003526440.026
cellular response to external stimulusGO:007149620.026
regulation of protein transportGO:005122330.026
cell part morphogenesisGO:00329902460.026
maintenance of locationGO:005123540.026
organic cyclic compound biosynthetic processGO:19013622230.025
cellular nitrogen compound biosynthetic processGO:00442712180.025
protein import into nucleusGO:000660630.025
heterocycle biosynthetic processGO:00181302150.025
lateral line system developmentGO:0048925760.025
positive regulation of catabolic processGO:000989640.025
response to chemicalGO:00422213200.025
neuron differentiationGO:00301823530.025
cognitionGO:005089010.024
protein localization to nucleusGO:003450430.024
stem cell maintenanceGO:001982740.024
system processGO:00030081850.024
cellular nitrogen compound metabolic processGO:00346412900.024
locomotionGO:00400113130.024
cellular macromolecule metabolic processGO:00442603910.024
nitrogen compound metabolic processGO:00068073190.024
modification dependent macromolecule catabolic processGO:004363230.024
sensory organ morphogenesisGO:00905962000.024
cellular component morphogenesisGO:00329893360.024
camera type eye developmentGO:00430102220.023
response to drugGO:004249330.023
lipid storageGO:001991510.023
regulation of primary metabolic processGO:00800903110.023
regulation of establishment of protein localizationGO:007020140.023
regulation of cellular biosynthetic processGO:00313262450.022
establishment of protein localization to organelleGO:007259440.022
regulation of developmental processGO:00507932470.022
sensory system developmentGO:0048880760.022
organic cyclic compound metabolic processGO:19013603010.022
regulation of cellular amine metabolic processGO:003323800.022
cellular response to extracellular stimulusGO:003166820.022
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.022
response to monosaccharideGO:003428430.022
cellular ketone metabolic processGO:0042180110.022
single organism metabolic processGO:00447102170.021
ubiquitin dependent protein catabolic processGO:000651130.021
lipid catabolic processGO:001604240.021
olfactory lobe developmentGO:002198840.021
amine metabolic processGO:000930820.021
nucleocytoplasmic transportGO:000691340.021
blood vessel developmentGO:00015682460.021
regulation of cellular amino acid metabolic processGO:000652100.021
positive regulation of cellular catabolic processGO:003133130.021
generation of neuronsGO:00486993850.021
compound eye developmentGO:004874920.021
inner ear developmentGO:00488391260.020
heterocycle metabolic processGO:00464832900.020
nuclear transportGO:005116940.020
response to carbohydrateGO:000974330.020
brain developmentGO:00074202930.020
cellular carbohydrate metabolic processGO:004426240.020
cellular amine metabolic processGO:004410620.020
negative regulation of protein phosphorylationGO:000193340.020
cellular response to nutrient levelsGO:003166920.020
regulation of macromolecule metabolic processGO:00602553170.020
cell migrationGO:00164772370.020
regulation of protein catabolic processGO:004217610.020
cell projection morphogenesisGO:00488582440.020
modification dependent protein catabolic processGO:001994130.020
regulation of cytoplasmic transportGO:190364940.020
cellular response to starvationGO:000926710.020
cellular aromatic compound metabolic processGO:00067252950.020
heart developmentGO:00075073130.020
meiotic cell cycle processGO:190304630.019
regulation of nitrogen compound metabolic processGO:00511712510.019
proteasomal protein catabolic processGO:001049820.019
gland developmentGO:00487321430.019
cell morphogenesisGO:00009022890.019
anterior posterior pattern specificationGO:00099521520.019
regulation of synaptic plasticityGO:004816710.019
ventricular cardiac muscle tissue developmentGO:000322930.019
eye morphogenesisGO:00485921440.019
aromatic compound biosynthetic processGO:00194382170.019
regulation of cellular ketone metabolic processGO:001056570.019
protein targeting to nucleusGO:004474430.018
response to hexoseGO:000974630.018
regulation of mrna processingGO:005068430.018
digestive tract morphogenesisGO:00485462310.018
adult behaviorGO:003053420.018
digestive system developmentGO:00551232890.018
development of primary female sexual characteristicsGO:004654540.018
skeletal system morphogenesisGO:00487051020.018
positive regulation of cellular component biogenesisGO:004408930.018
negative regulation of biological processGO:00485193040.018
regulation of cell activationGO:005086510.018
epidermal cell fate specificationGO:000995740.018
water homeostasisGO:003010440.018
embryonic skeletal system morphogenesisGO:0048704930.018
regulation of reproductive processGO:200024140.018
regulation of multicellular organismal processGO:00512392770.018
rna metabolic processGO:00160702190.018
specification of symmetryGO:00097992040.018
nucleobase containing compound biosynthetic processGO:00346542050.017
chemosensory behaviorGO:000763510.017
protein importGO:001703830.017
regulation of peptidyl tyrosine phosphorylationGO:005073010.017
meiotic nuclear divisionGO:000712640.017
neuron neuron synaptic transmissionGO:000727010.017
regulation of synapse assemblyGO:005196330.017
regulation of biosynthetic processGO:00098892500.017
oxoacid metabolic processGO:0043436310.017
regulation of metal ion transportGO:001095940.017
golgi vesicle transportGO:004819330.017
olfactory bulb developmentGO:002177240.017
macromolecule biosynthetic processGO:00090592270.017
response to glucoseGO:000974930.017
regulation of protein targetingGO:190353320.017
determination of bilateral symmetryGO:00098552040.017
regulation of nucleocytoplasmic transportGO:004682220.017
vasculature developmentGO:00019442780.017
regulation of cell communicationGO:00106462320.017
autophagyGO:000691440.017
negative regulation of protein kinase activityGO:000646940.017
regulation of signalingGO:00230512350.017
central nervous system developmentGO:00074173870.017
regulation of stem cell differentiationGO:200073640.017
mesenchyme developmentGO:00604851270.017
epithelial tube morphogenesisGO:00605621480.017
positive regulation of cellular amine metabolic processGO:003324000.017
nucleic acid metabolic processGO:00903042440.016
regulation of neural precursor cell proliferationGO:200017730.016
fin morphogenesisGO:0033334530.016
cell projection organizationGO:00300302840.016
regulation of rna metabolic processGO:00512522240.016
regulation of blood vessel sizeGO:005088020.016
nuclear importGO:005117030.016
glucose homeostasisGO:004259310.016
regulation of synaptic growth at neuromuscular junctionGO:000858210.016
transcription from rna polymerase ii promoterGO:0006366800.016
digestive tract developmentGO:00485652650.016
synaptic growth at neuromuscular junctionGO:005112420.016
single organism localizationGO:19025782250.016
cellular macromolecule biosynthetic processGO:00346452240.016
regulation of metabolic processGO:00192223590.016
female sex differentiationGO:004666040.016
gene expressionGO:00104672520.016
negative regulation of map kinase activityGO:004340720.015
regulation of response to stimulusGO:00485832690.015
regulation of bindingGO:005109830.015
regulation of cytokine productionGO:000181730.015
gastrulationGO:00073692080.015
stem cell proliferationGO:007208940.015
regulation of intracellular protein transportGO:003315730.015
positive regulation of cytokine productionGO:000181920.015
purine ribonucleoside monophosphate catabolic processGO:000916940.015
embryonic heart tube developmentGO:00350501330.015
organic acid metabolic processGO:0006082310.015
single organism nuclear importGO:190259330.015
regulation of nucleic acid templated transcriptionGO:19035062130.015
transportGO:00068102200.015
ribonucleoside monophosphate catabolic processGO:000915840.015
cell motilityGO:00488702440.015
retina development in camera type eyeGO:00600411460.015
positive regulation of secretionGO:005104710.015
internal peptidyl lysine acetylationGO:001839320.015
neuron projection developmentGO:00311751800.015
hormone secretionGO:004687920.015
regulation of meiotic cell cycleGO:005144510.015
synaptic vesicle localizationGO:009747910.015
regulation of tube sizeGO:003515020.015
regulation of protein complex assemblyGO:004325430.015
positive regulation of blood circulationGO:190352420.015
energy reserve metabolic processGO:000611220.015
embryonic cranial skeleton morphogenesisGO:0048701900.015
rna biosynthetic processGO:00327741810.015
regulation of blood pressureGO:000821710.015
negative regulation of kinase activityGO:003367340.014
peptidyl lysine acetylationGO:001839420.014
actin polymerization or depolymerizationGO:000815420.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
positive regulation of cellular amino acid metabolic processGO:004576400.014
ear morphogenesisGO:0042471640.014
circulatory system processGO:0003013870.014
regulation of biological qualityGO:00650082630.014
regulation of multicellular organismal developmentGO:20000262230.014
meiotic chromosome segregationGO:004513230.014
regulation of cell shapeGO:000836010.014
response to topologically incorrect proteinGO:003596620.014
atp catabolic processGO:000620040.014
regulation of cellular metabolic processGO:00313233200.014
adherens junction organizationGO:003433240.014
b cell activationGO:004211320.014
cell substrate adhesionGO:003158940.014
regulation of circadian rhythmGO:004275240.014
extrinsic apoptotic signaling pathwayGO:009719130.014
nucleic acid templated transcriptionGO:00976591810.014
inositol lipid mediated signalingGO:004801720.014
epithelial cell differentiationGO:00308551160.014
regulation of signal transductionGO:00099662250.014
protein acetylationGO:000647320.014
regulation of ion transmembrane transporter activityGO:003241220.014
regulation of synapse organizationGO:005080730.014
cellular component disassemblyGO:002241110.014
mitochondrion organizationGO:000700540.014
carbohydrate homeostasisGO:003350010.014
axon developmentGO:00615641660.014
cell morphogenesis involved in differentiationGO:00009041950.014
sensory perception of chemical stimulusGO:000760630.014
internal protein amino acid acetylationGO:000647520.014
regulation of reactive oxygen species metabolic processGO:200037720.014
protein acylationGO:004354330.014
neuromast developmentGO:0048884460.014
negative regulation of stem cell differentiationGO:200073720.014
nucleoside monophosphate catabolic processGO:000912540.014
organonitrogen compound metabolic processGO:1901564740.014
hormone transportGO:000991420.014
small molecule metabolic processGO:0044281770.014
embryo development ending in birth or egg hatchingGO:00097922710.014
cellular component assembly involved in morphogenesisGO:00109271070.014
blood circulationGO:0008015870.014
regulation of protein localization to nucleusGO:190018020.013
positive regulation of cell cycleGO:004578730.013
inner ear morphogenesisGO:0042472630.013
nucleobase containing compound metabolic processGO:00061392740.013
carbohydrate biosynthetic processGO:001605110.013
regulation of cellular carbohydrate metabolic processGO:001067540.013
central nervous system myelinationGO:002201020.013
cellular amino acid metabolic processGO:000652070.013
localization of cellGO:00516742440.013
negative regulation of protein serine threonine kinase activityGO:007190120.013
hemopoiesisGO:00300971830.013
regulation of nucleobase containing compound metabolic processGO:00192192500.013
otic vesicle developmentGO:0071599420.013
regulation of cell substrate adhesionGO:001081010.013
production of molecular mediator of immune responseGO:000244020.013
regulation of transcription dna templatedGO:00063552130.013
protein stabilizationGO:005082120.013
regulation of extrinsic apoptotic signaling pathwayGO:200123630.013
female gonad developmentGO:000858540.013
regulation of rna biosynthetic processGO:20011412130.013
stem cell differentiationGO:00488631170.013
regulation of sodium ion transportGO:000202820.013
pectoral fin developmentGO:0033339500.013
negative regulation of cellular processGO:00485232830.013
determination of left right symmetryGO:00073681790.013
positive regulation of secretion by cellGO:190353210.013
establishment of localizationGO:00512342440.013
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.013
regulation of gene expressionGO:00104682650.013
transcription dna templatedGO:00063511810.013
response to alkaloidGO:004327920.013
neurotransmitter transportGO:000683620.013
phagocytosis engulfmentGO:000691110.013
positive regulation of epithelial cell differentiationGO:003085820.013
regulation of dendrite developmentGO:005077330.013
small molecule catabolic processGO:004428230.013
amino acid transportGO:000686520.013
protein dephosphorylationGO:000647030.013
heart loopingGO:0001947940.013
cellular response to chemical stimulusGO:00708871570.013
synaptic vesicle transportGO:004848910.013
mesenchymal cell developmentGO:0014031780.013
regulation of inflammatory responseGO:005072720.013
protein secretionGO:000930610.012
immune system processGO:00023762410.012
muscle structure developmentGO:00610611960.012
protein localization to plasma membraneGO:007265910.012
sequestering of metal ionGO:005123830.012
cellular amide metabolic processGO:004360340.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
positive regulation of immune effector processGO:000269930.012
heart morphogenesisGO:00030071560.012
hatchingGO:003518840.012
membrane invaginationGO:001032410.012
epidermis developmentGO:0008544480.012
response to uvGO:000941130.012
peptide transportGO:001583310.012
regulation of transporter activityGO:003240920.012
regulation of transmembrane transporter activityGO:002289820.012
neurological system processGO:0050877620.012
response to external stimulusGO:00096052640.012
negative regulation of reproductive processGO:200024230.012
single organism biosynthetic processGO:0044711710.012
guanosine containing compound metabolic processGO:190106840.012
locomotor rhythmGO:004547530.012
regulation of protein modification by small protein conjugation or removalGO:190332030.012
negative regulation of cytoplasmic transportGO:190365020.012
positive regulation of cytoskeleton organizationGO:005149530.012
somite developmentGO:0061053960.012
regulation of hormone secretionGO:004688320.012
protein metabolic processGO:00195381830.012
negative regulation of catabolic processGO:000989530.012
regulation of stem cell proliferationGO:007209120.012
germ line stem cell maintenanceGO:003071820.012
sleepGO:003043110.012
regulation of cell differentiationGO:00455951420.012
cell deathGO:00082191210.012
single organism transportGO:00447652060.012
positive regulation of dna metabolic processGO:005105410.012
connective tissue developmentGO:0061448990.012
neural crest cell differentiationGO:0014033720.012
endocrine processGO:005088620.011
hematopoietic or lymphoid organ developmentGO:00485341910.011
regulation of carbohydrate metabolic processGO:000610940.011
interspecies interaction between organismsGO:004441940.011
regulation of calcium ion transportGO:005192420.011
cartilage developmentGO:0051216960.011
secondary metabolic processGO:001974830.011
rna localizationGO:000640340.011
cell matrix adhesionGO:000716040.011
immune system developmentGO:00025201910.011
wnt signaling pathwayGO:0016055800.011
organelle assemblyGO:00709251100.011
peptidyl serine modificationGO:001820920.011
cranial ganglion developmentGO:006155030.011
tissue remodelingGO:004877140.011
spermatid developmentGO:000728620.011
positive regulation of reproductive processGO:200024320.011
carboxylic acid metabolic processGO:0019752220.011
cellular component biogenesisGO:00440851780.011
cellular response to molecule of bacterial originGO:007121930.011
establishment of synaptic vesicle localizationGO:009748010.011
cellular response to reactive oxygen speciesGO:003461420.011
gtp catabolic processGO:000618420.011
cytoplasm organizationGO:000702840.011
regulation of macromolecule biosynthetic processGO:00105562250.011
protein heterooligomerizationGO:005129110.011
mesenchymal cell differentiationGO:0048762870.011
epidermal cell differentiationGO:0009913360.011
regulation of autophagyGO:001050630.011
leukocyte proliferationGO:007066110.011
spermatid differentiationGO:004851520.011
protein polymerizationGO:005125840.011
angiogenesisGO:00015251580.011
growthGO:00400071740.011
somatic muscle developmentGO:000752540.011
response to nutrientGO:000758430.011
fin developmentGO:0033333770.011
ameboidal type cell migrationGO:00016671430.011
response to other organismGO:0051707970.011
cytokinesisGO:000091030.011
symbiosis encompassing mutualism through parasitismGO:004440340.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
neuron projection morphogenesisGO:00488121610.011
somatic stem cell maintenanceGO:003501910.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
regulation of i kappab kinase nf kappab signalingGO:004312240.011
er nucleus signaling pathwayGO:000698420.011
regulation of alternative mrna splicing via spliceosomeGO:000038110.011
lymphocyte proliferationGO:004665110.011
mesoderm developmentGO:0007498880.011
regulation of production of molecular mediator of immune responseGO:000270010.011
smooth muscle contractionGO:000693920.011
neurotransmitter secretionGO:000726920.011
notochord developmentGO:0030903540.011
regulation of cellular protein catabolic processGO:190336210.011
regulation of mrna splicing via spliceosomeGO:004802430.011
maternal determination of anterior posterior axis embryoGO:000835840.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.011
regulation of skeletal muscle tissue developmentGO:004864140.011
exocytosisGO:000688710.011
guanosine containing compound catabolic processGO:190106920.011
blood vessel morphogenesisGO:00485142160.011
hatching gland developmentGO:004878530.011
endosomal transportGO:001619720.011
response to corticosteroidGO:003196010.011
negative regulation of synapse assemblyGO:005196420.011
cranial nerve developmentGO:0021545420.011
negative regulation of protein localization to nucleusGO:190018120.011
axonogenesisGO:00074091520.011
regulation of apoptotic processGO:0042981980.011
negative regulation of protein transportGO:005122430.011
phosphatidylinositol 3 kinase signalingGO:001406520.010
macroautophagyGO:001623610.010
regulation of protein import into nucleusGO:004230620.010
protein homooligomerizationGO:005126030.010
outflow tract morphogenesisGO:000315110.010
peptidyl threonine phosphorylationGO:001810710.010
regulation of protein polymerizationGO:003227120.010
mononuclear cell proliferationGO:003294310.010
macromolecular complex disassemblyGO:003298410.010
regulation of cellular macromolecule biosynthetic processGO:20001122220.010
organism emergence from protective structureGO:007168440.010
er to golgi vesicle mediated transportGO:000688810.010
fertilizationGO:000956630.010
lateral line developmentGO:0048882660.010
retina morphogenesis in camera type eyeGO:0060042790.010
antimicrobial humoral responseGO:001973020.010
negative regulation of defense responseGO:003134820.010
regulation of systemic arterial blood pressureGO:000307310.010
negative regulation of mapk cascadeGO:004340940.010
sequestering of calcium ionGO:005120830.010
sympathetic nervous system developmentGO:004848530.010
cellular response to radiationGO:007147840.010
post embryonic organ developmentGO:004856940.010
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.010
dorsal ventral pattern formationGO:00099531250.010
positive regulation of cell activationGO:005086710.010
embryonic heart tube morphogenesisGO:00031431080.010
regulation of neuronal synaptic plasticityGO:004816810.010
regulation of endocrine processGO:004406020.010
somitogenesisGO:0001756870.010
response to stressGO:00069502630.010
response to organic substanceGO:00100331530.010
response to unfolded proteinGO:000698620.010
cellular lipid catabolic processGO:004424230.010
lateral inhibitionGO:004633110.010

otol1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
musculoskeletal system diseaseDOID:1700.023
disease of metabolismDOID:001466700.017
nervous system diseaseDOID:86300.013
cardiovascular system diseaseDOID:128700.013
cancerDOID:16200.012
disease of cellular proliferationDOID:1456600.012
muscular diseaseDOID:008000000.011
immune system diseaseDOID:291400.011
connective tissue diseaseDOID:6500.011