Danio rerio

0 known processes

cotl1

coactosin-like 1 (Dictyostelium)

(Aliases: zgc:63983,wu:fb08h08)

cotl1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of protein polymerizationGO:003227120.933
actin polymerization or depolymerizationGO:000815420.884
actin filament polymerizationGO:003004120.862
regulation of cell projection assemblyGO:006049140.614
regulation of filopodium assemblyGO:005148920.576
regulation of actin cytoskeleton organizationGO:003295680.573
regulation of protein complex assemblyGO:004325430.534
regulation of actin filament based processGO:003297090.502
positive regulation of protein polymerizationGO:003227320.487
positive regulation of protein complex assemblyGO:003133420.445
cellular component movementGO:00069283350.444
actin filament based processGO:0030029640.407
actin filament organizationGO:0007015150.406
positive regulation of cellular component biogenesisGO:004408930.395
protein polymerizationGO:005125840.371
positive regulation of cytoskeleton organizationGO:005149530.267
cell adhesion mediated by integrinGO:003362710.247
single organism organelle organizationGO:19025891990.243
regulation of cytoskeleton organizationGO:0051493110.242
actin cytoskeleton organizationGO:0030036630.217
larval developmentGO:000216420.213
protein complex assemblyGO:0006461300.212
biological adhesionGO:0022610400.176
cellular component biogenesisGO:00440851780.173
transportGO:00068102200.173
superoxide metabolic processGO:000680120.164
cellular component assemblyGO:00226071700.160
gtp metabolic processGO:004603940.151
macromolecular complex assemblyGO:0065003350.146
organelle organizationGO:00069962270.133
cellular protein complex assemblyGO:0043623190.131
response to drugGO:004249330.131
negative regulation of protein complex assemblyGO:003133310.128
positive regulation of cellular catabolic processGO:003133130.127
regulation of biological qualityGO:00650082630.123
establishment of protein localization to organelleGO:007259440.121
sensory organ developmentGO:00074233930.118
phagocytosisGO:000690930.116
positive regulation of apoptotic signaling pathwayGO:200123510.114
small molecule metabolic processGO:0044281770.111
single organism metabolic processGO:00447102170.107
cell projection assemblyGO:0030031640.106
eye developmentGO:00016542770.106
regulation of peptidyl tyrosine phosphorylationGO:005073010.105
tube morphogenesisGO:00352393490.105
positive regulation of notch signaling pathwayGO:004574730.103
localization of cellGO:00516742440.102
apoptotic processGO:00069151160.102
guanosine containing compound catabolic processGO:190106920.101
regulation of interferon beta productionGO:003264810.098
macromolecular complex subunit organizationGO:0043933740.091
cytoskeleton organizationGO:0007010960.089
single organism transportGO:00447652060.089
pole plasm assemblyGO:000731540.087
maintenance of locationGO:005123540.086
agingGO:000756820.085
digestive system developmentGO:00551232890.083
response to chemicalGO:00422213200.083
positive regulation of biological processGO:00485182530.082
organonitrogen compound metabolic processGO:1901564740.078
sphingolipid biosynthetic processGO:003014820.076
cellular component disassemblyGO:002241110.076
negative regulation of sequestering of calcium ionGO:005128340.074
protein complex subunit organizationGO:0071822460.069
morphogenesis of an epitheliumGO:00020093330.068
nuclear transportGO:005116940.068
lamellipodium assemblyGO:003003210.067
protein complex biogenesisGO:0070271300.066
stem cell maintenanceGO:001982740.065
negative regulation of kinase activityGO:003367340.065
chromosome organizationGO:0051276310.064
regulation of i kappab kinase nf kappab signalingGO:004312240.062
regulation of cellular component organizationGO:0051128860.062
protein complex disassemblyGO:004324110.060
release of sequestered calcium ion into cytosolGO:005120930.059
signal transductionGO:00071654550.057
mononuclear cell proliferationGO:003294310.057
nitrogen compound metabolic processGO:00068073190.057
response to external biotic stimulusGO:0043207970.057
Mouse
cellular component morphogenesisGO:00329893360.055
organic substance biosynthetic processGO:19015762890.055
cellular localizationGO:0051641970.055
phagocytosis engulfmentGO:000691110.054
leukocyte proliferationGO:007066110.054
synaptic vesicle endocytosisGO:004848810.053
gastrulation with mouth forming secondGO:0001702440.052
regulation of cell communicationGO:00106462320.051
cell cycleGO:0007049930.051
carbohydrate derivative metabolic processGO:1901135610.050
regulation of multicellular organism growthGO:004001440.050
positive regulation of catabolic processGO:000989640.050
convergent extension involved in gastrulationGO:0060027710.050
response to external stimulusGO:00096052640.050
Mouse
single organism biosynthetic processGO:0044711710.049
regulation of organelle organizationGO:0033043290.049
regulation of anatomical structure morphogenesisGO:00226031300.049
establishment of localizationGO:00512342440.049
regulation of nucleotide catabolic processGO:003081120.048
positive regulation of signalingGO:0023056560.047
guanosine containing compound metabolic processGO:190106840.047
cytoplasm organizationGO:000702840.046
cell migrationGO:00164772370.046
regulation of cell differentiationGO:00455951420.045
regulation of cellular component sizeGO:0032535300.045
cellular amino acid metabolic processGO:000652070.045
regulation of establishment of protein localizationGO:007020140.045
regulation of protein depolymerizationGO:190187910.045
positive regulation of cell communicationGO:0010647560.044
regulation of gtp catabolic processGO:003312420.044
cellular response to nutrient levelsGO:003166920.044
muscle structure developmentGO:00610611960.044
regulation of purine nucleotide catabolic processGO:003312120.044
negative regulation of protein serine threonine kinase activityGO:007190120.043
carboxylic acid metabolic processGO:0019752220.043
cell surface receptor signaling pathwayGO:00071663250.043
response to abiotic stimulusGO:00096281220.043
positive regulation of cellular processGO:00485222010.042
cellular biosynthetic processGO:00442492860.042
regulation of cell projection organizationGO:0031344440.042
negative regulation of biological processGO:00485193040.042
regulation of cell shapeGO:000836010.041
cellular response to external stimulusGO:007149620.040
somatic muscle developmentGO:000752540.040
organelle assemblyGO:00709251100.040
cellular protein metabolic processGO:00442671290.040
meiotic nuclear divisionGO:000712640.040
internal peptidyl lysine acetylationGO:001839320.040
cell adhesionGO:0007155400.040
regulation of cell activationGO:005086510.039
cell deathGO:00082191210.039
axonal fasciculationGO:0007413110.039
regulation of signalingGO:00230512350.039
oxoacid metabolic processGO:0043436310.039
regulation of protein complex disassemblyGO:004324410.038
cell morphogenesis involved in differentiationGO:00009041950.038
protein acetylationGO:000647320.038
multicellular organismal metabolic processGO:004423620.038
multi organism processGO:00517041340.037
Mouse
positive regulation of transportGO:005105020.037
regulation of gtpase activityGO:004308720.037
heterocycle metabolic processGO:00464832900.037
digestive tract developmentGO:00485652650.037
regulation of response to stimulusGO:00485832690.036
single organism localizationGO:19025782250.036
regulation of wound healingGO:006104120.036
cellular nitrogen compound metabolic processGO:00346412900.036
protein heterooligomerizationGO:005129110.036
peptidyl lysine acetylationGO:001839420.036
meiotic chromosome segregationGO:004513230.036
adherens junction organizationGO:003433240.036
digestive tract morphogenesisGO:00485462310.036
embryo development ending in birth or egg hatchingGO:00097922710.036
sequestering of metal ionGO:005123830.036
response to mechanical stimulusGO:0009612240.036
cellular amine metabolic processGO:004410620.035
regulation of protein localization to nucleusGO:190018020.035
regulation of cellular component biogenesisGO:0044087120.035
extrinsic apoptotic signaling pathwayGO:009719130.035
muscle cell differentiationGO:00426921390.035
convergent extensionGO:00600261180.035
negative regulation of mapk cascadeGO:004340940.034
regulation of signal transductionGO:00099662250.034
homeostatic processGO:00425921420.034
nuclear migrationGO:000709730.032
cellular protein modification processGO:00064641000.032
wound healingGO:0042060900.032
maternal determination of anterior posterior axis embryoGO:000835840.031
cellular macromolecule localizationGO:0070727210.031
regulation of stem cell differentiationGO:200073640.031
protein import into nucleusGO:000660630.031
autophagyGO:000691440.030
single organism nuclear importGO:190259330.030
gtp catabolic processGO:000618420.030
response to carbohydrateGO:000974330.030
cellular response to chemical stimulusGO:00708871570.030
cellular macromolecular complex assemblyGO:0034622240.030
organic acid metabolic processGO:0006082310.029
response to hydrogen peroxideGO:004254230.029
regulation of cell substrate adhesionGO:001081010.029
positive regulation of oocyte developmentGO:006028210.029
protein depolymerizationGO:005126110.029
multicellular organism growthGO:003526440.028
organic cyclic compound metabolic processGO:19013603010.028
cell agingGO:000756920.028
regulation of protein import into nucleusGO:004230620.028
response to biotic stimulusGO:0009607970.027
Mouse
regulation of apoptotic processGO:0042981980.027
response to monosaccharideGO:003428430.027
deathGO:00162651210.027
internal protein amino acid acetylationGO:000647520.027
negative regulation of cellular processGO:00485232830.027
nucleocytoplasmic transportGO:000691340.027
ameboidal type cell migrationGO:00016671430.027
response to xenobiotic stimulusGO:0009410450.027
regulation of bindingGO:005109830.027
cellular component assembly involved in morphogenesisGO:00109271070.027
cell morphogenesisGO:00009022890.026
histone modificationGO:0016570200.026
single organism cell adhesionGO:0098602290.026
amine metabolic processGO:000930820.026
lymphocyte proliferationGO:004665110.026
immune system processGO:00023762410.025
positive regulation of nucleotide catabolic processGO:003081310.025
stem cell proliferationGO:007208940.025
protein importGO:001703830.025
generation of neuronsGO:00486993850.025
cell projection morphogenesisGO:00488582440.025
regulation of nucleoside metabolic processGO:000911820.025
purine nucleoside monophosphate catabolic processGO:000912840.025
membrane lipid biosynthetic processGO:004646720.025
gene expressionGO:00104672520.025
regulation of anatomical structure sizeGO:0090066330.025
regulation of developmental processGO:00507932470.025
positive regulation of gtp catabolic processGO:003312610.024
signal transduction in absence of ligandGO:003803410.024
embryonic organ developmentGO:00485683810.024
synaptic vesicle localizationGO:009747910.024
cell substrate adhesionGO:003158940.024
protein acylationGO:004354330.024
phosphate containing compound metabolic processGO:00067961080.024
multicellular organismal macromolecule metabolic processGO:004425920.024
cell substrate junction assemblyGO:000704420.023
regulation of cell maturationGO:190342910.023
response to hexoseGO:000974630.023
cell motilityGO:00488702440.023
purine containing compound metabolic processGO:0072521290.023
hemopoiesisGO:00300971830.023
regulation of cell morphogenesisGO:0022604420.023
protein localization to nucleusGO:003450430.023
sleepGO:003043110.023
regulation of intracellular protein transportGO:003315730.023
cortical cytoskeleton organizationGO:003086510.023
programmed cell deathGO:00125011190.023
cellular response to organic substanceGO:00713101050.023
cell cycle processGO:0022402530.023
locomotionGO:00400113130.022
positive regulation of cellular component organizationGO:0051130130.022
ion transportGO:00068111140.022
negative regulation of protein kinase activityGO:000646940.022
regulation of cytoplasmic transportGO:190364940.022
regulation of glucose transportGO:001082710.022
nuclear importGO:005117030.022
positive regulation of glucose importGO:004632610.022
positive regulation of cell matrix adhesionGO:000195410.022
regulation of mrna processingGO:005068430.022
determination of left right symmetryGO:00073681790.022
sarcomere organizationGO:0045214260.022
negative regulation of map kinase activityGO:004340720.022
macromolecular complex disassemblyGO:003298410.022
type i interferon productionGO:003260620.021
reproductionGO:0000003400.021
positive regulation of defense response to virus by hostGO:000223000.021
i kappab kinase nf kappab signalingGO:000724940.021
organonitrogen compound biosynthetic processGO:1901566470.021
protein metabolic processGO:00195381830.021
peptidyl threonine phosphorylationGO:001810710.021
regulation of alternative mrna splicing via spliceosomeGO:000038110.021
regulation of calcium ion transportGO:005192420.021
positive regulation of cellular amine metabolic processGO:003324000.021
cellular ketone metabolic processGO:0042180110.021
cellular modified amino acid metabolic processGO:000657530.021
positive regulation of cytosolic calcium ion concentrationGO:000720440.020
cytosolic calcium ion transportGO:006040130.020
cellular aromatic compound metabolic processGO:00067252950.020
macromolecule localizationGO:0033036540.020
oocyte anterior posterior axis specificationGO:000731440.020
membrane invaginationGO:001032410.020
regulation of macromolecule metabolic processGO:00602553170.020
regulation of cardiac muscle contractionGO:005511720.019
regulation of ion transmembrane transporter activityGO:003241220.019
gastrulationGO:00073692080.019
neuroblast proliferationGO:000740520.019
cell matrix adhesionGO:000716040.019
phagolysosome assemblyGO:000184510.019
neuron projection developmentGO:00311751800.019
mitochondrion organizationGO:000700540.019
protein localization to plasma membraneGO:007265910.019
regulation of metal ion transportGO:001095940.018
nucleobase containing compound metabolic processGO:00061392740.018
regulation of cellular ketone metabolic processGO:001056570.018
rna 3 end processingGO:003112320.018
regulation of protein targetingGO:190353320.018
collagen metabolic processGO:003296320.018
regulation of extrinsic apoptotic signaling pathwayGO:200123630.018
b cell activationGO:004211320.018
very long chain fatty acid metabolic processGO:000003840.018
ion transmembrane transportGO:0034220910.018
lamellipodium organizationGO:009758110.018
positive regulation of response to stimulusGO:0048584800.018
cellular macromolecule metabolic processGO:00442603910.018
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.018
trabecula formationGO:006034320.018
regulation of purine nucleotide metabolic processGO:1900542170.018
zymogen activationGO:003163830.017
regulation of rho protein signal transductionGO:003502320.017
leukocyte homeostasisGO:000177620.017
response to other organismGO:0051707970.017
Mouse
atrioventricular valve developmentGO:0003171110.017
negative regulation of nuclear divisionGO:005178430.017
cytokinesisGO:000091030.017
spermatid differentiationGO:004851520.017
notch signaling pathwayGO:0007219350.017
synaptic vesicle transportGO:004848910.017
cell morphogenesis involved in neuron differentiationGO:00486671630.016
intracellular signal transductionGO:0035556850.016
regulation of synaptic growth at neuromuscular junctionGO:000858210.016
peptide transportGO:001583310.016
regulation of cellular protein metabolic processGO:0032268520.016
cortical actin cytoskeleton organizationGO:003086610.016
neutrophil mediated immunityGO:000244610.016
regulation of nitrogen compound metabolic processGO:00511712510.016
segmentationGO:0035282970.016
cardiac muscle cell contractionGO:008600310.016
regulation of epithelial cell proliferationGO:005067830.016
neurotransmitter transportGO:000683620.016
interferon beta productionGO:003260810.016
spermatid developmentGO:000728620.016
neuron developmentGO:00486662620.016
protein targeting to nucleusGO:004474430.016
response to stressGO:00069502630.016
Mouse
organelle fusionGO:004828430.016
regulation of nucleocytoplasmic transportGO:004682220.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
negative regulation of defense responseGO:003134820.015
positive regulation of gtpase activityGO:004354710.015
regulation of transporter activityGO:003240920.015
meiotic cell cycle processGO:190304630.015
chordate embryonic developmentGO:00430092710.015
medulla oblongata developmentGO:002155040.015
nucleoside monophosphate catabolic processGO:000912540.015
positive regulation of purine nucleotide catabolic processGO:003312310.015
response to glucoseGO:000974930.015
membrane fusionGO:006102520.015
melanin metabolic processGO:000658220.015
positive regulation of secretion by cellGO:190353210.015
regulation of epithelial to mesenchymal transitionGO:001071730.015
single organismal cell cell adhesionGO:0016337290.015
head developmentGO:00603223030.015
ribonucleoside monophosphate catabolic processGO:000915840.015
membrane organizationGO:0061024210.014
digestive tract mesoderm developmentGO:000750210.014
biosynthetic processGO:00090582940.014
amino acid transportGO:000686520.014
negative regulation of cell projection organizationGO:003134590.014
reactive oxygen species metabolic processGO:007259360.014
establishment of synaptic vesicle localizationGO:009748010.014
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.014
cell projection organizationGO:00300302840.014
establishment of organelle localizationGO:0051656450.014
regulation of ras gtpase activityGO:003231820.014
striated muscle cell differentiationGO:00511461290.014
regulation of transmembrane transporter activityGO:002289820.014
blood vessel morphogenesisGO:00485142160.014
germ line stem cell maintenanceGO:003071820.014
positive regulation of cell activationGO:005086710.014
positive regulation of map kinase activityGO:004340630.014
regulation of glucose importGO:004632410.014
sequestering of calcium ionGO:005120830.014
axon developmentGO:00615641660.014
rho protein signal transductionGO:000726650.014
trabecula morphogenesisGO:006138320.014
vasculature developmentGO:00019442780.014
cellular protein complex disassemblyGO:004362410.014
protein dephosphorylationGO:000647030.014
organic substance transportGO:0071702580.014
negative regulation of protein phosphorylationGO:000193340.014
smooth muscle contractionGO:000693920.013
positive regulation of cell adhesionGO:004578510.013
regulation of cell deathGO:00109411030.013
macromolecule modificationGO:00434121110.013
positive regulation of nucleoside metabolic processGO:004597910.013
atp catabolic processGO:000620040.013
cell proliferationGO:0008283800.013
cellular extravasationGO:004512310.013
dicarboxylic acid transportGO:000683510.013
regulation of cellular amine metabolic processGO:003323800.013
filopodium assemblyGO:004684750.013
camera type eye developmentGO:00430102220.013
cell substrate adherens junction assemblyGO:000704510.013
response to organic substanceGO:00100331530.013
positive regulation of secretionGO:005104710.013
positive regulation of ras gtpase activityGO:003232010.013
dorsal motor nucleus of vagus nerve developmentGO:002174440.013
endocardial cushion formationGO:000327220.013
protein localizationGO:0008104400.013
energy reserve metabolic processGO:000611220.013
developmental growthGO:00485891660.013
regulation of reactive oxygen species metabolic processGO:200037720.013
single organism membrane fusionGO:004480120.013
regulation of neurotransmitter secretionGO:004692810.013
response to inorganic substanceGO:0010035380.012
regulation of blood coagulationGO:003019310.012
positive regulation of erk1 and erk2 cascadeGO:007037420.012
regulation of synapse organizationGO:005080730.012
estrogen metabolic processGO:000821020.012
regulation of striated muscle contractionGO:000694220.012
anterior posterior pattern specificationGO:00099521520.012
cellular macromolecule biosynthetic processGO:00346452240.012
cognitionGO:005089010.012
cellular response to extracellular stimulusGO:003166820.012
determination of bilateral symmetryGO:00098552040.012
cellular response to retinoic acidGO:007130010.012
coagulationGO:0050817130.012
positive regulation of signal transductionGO:0009967560.012
regulation of metabolic processGO:00192223590.012
kidney developmentGO:0001822920.012
regulation of nucleobase containing compound metabolic processGO:00192192500.012
membrane lipid metabolic processGO:0006643100.012
brain developmentGO:00074202930.012
neuron projection morphogenesisGO:00488121610.012
regulation of cellular amino acid metabolic processGO:000652100.012
cellular response to endogenous stimulusGO:0071495680.012
cell recognitionGO:0008037190.012
positive regulation of embryonic developmentGO:004001930.012
regulation of defense response to virus by hostGO:005069110.012
regulation of protein transportGO:005122330.012
negative regulation of i kappab kinase nf kappab signalingGO:004312410.011
cellular response to starvationGO:000926710.011
central nervous system projection neuron axonogenesisGO:0021952150.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
hormone secretionGO:004687920.011
regulation of rho gtpase activityGO:003231910.011
system processGO:00030081850.011
cellular component maintenanceGO:004395430.011
calcium ion transport into cytosolGO:006040230.011
regulation of programmed cell deathGO:00430671010.011
myeloid cell homeostasisGO:0002262560.011
regulation of sequestering of calcium ionGO:005128240.011
regulation of primary metabolic processGO:00800903110.011
central nervous system developmentGO:00074173870.011
carbohydrate derivative biosynthetic processGO:1901137430.011
positive regulation of cell projection organizationGO:003134690.011
neuron differentiationGO:00301823530.011
hemostasisGO:0007599130.011
organophosphate metabolic processGO:0019637370.011
positive regulation of cell substrate adhesionGO:001081110.011
lipid catabolic processGO:001604240.011
muscle system processGO:0003012200.011
regulation of release of sequestered calcium ion into cytosolGO:005127910.011
cation transmembrane transportGO:0098655650.011
long chain fatty acid biosynthetic processGO:004275910.011
regulation of mrna catabolic processGO:006101330.011
muscle cell developmentGO:00550011150.011
female meiotic divisionGO:000714320.011
epithelial cell migrationGO:0010631250.011
chromatin organizationGO:0006325220.010
sensory system developmentGO:0048880760.010
striated muscle cell developmentGO:00550021080.010
positive regulation of canonical wnt signaling pathwayGO:009026340.010
regulation of localizationGO:00328791040.010
compound eye developmentGO:004874920.010
fatty acid biosynthetic processGO:000663340.010
synaptic vesicle recyclingGO:003646510.010
immune responseGO:0006955280.010
regulation of cellular component movementGO:0051270550.010
regulation of notch signaling pathwayGO:0008593160.010
regulation of type i interferon productionGO:003247920.010
peptidyl serine modificationGO:001820920.010

cotl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.099
immune system diseaseDOID:291400.025
primary immunodeficiency diseaseDOID:61200.025
disease of metabolismDOID:001466700.017
nervous system diseaseDOID:86300.017