Danio rerio

23 known processes

dyrk1b

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B

(Aliases: si:ch211-225p5.1)

dyrk1b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
convergent extension involved in gastrulationGO:0060027710.303
rna metabolic processGO:00160702190.204
Human
regulation of gene expressionGO:00104682650.181
Human
signal transductionGO:00071654550.169
cellular nitrogen compound metabolic processGO:00346412900.167
Human
cell surface receptor signaling pathwayGO:00071663250.165
regulation of multicellular organism growthGO:004001440.149
regionalizationGO:00030022740.135
multicellular organism growthGO:003526440.133
specification of symmetryGO:00097992040.126
negative regulation of biological processGO:00485193040.121
central nervous system developmentGO:00074173870.121
brain developmentGO:00074202930.109
digestive tract developmentGO:00485652650.106
tube morphogenesisGO:00352393490.103
convergent extensionGO:00600261180.102
head developmentGO:00603223030.101
regulation of metabolic processGO:00192223590.101
Human
gene expressionGO:00104672520.099
Human
sensory organ developmentGO:00074233930.097
regulation of signalingGO:00230512350.097
gastrulationGO:00073692080.097
wnt signaling pathwayGO:0016055800.095
determination of bilateral symmetryGO:00098552040.094
stem cell maintenanceGO:001982740.094
morphogenesis of an epitheliumGO:00020093330.088
cellular macromolecule metabolic processGO:00442603910.087
Human Yeast
regulation of multicellular organismal developmentGO:20000262230.087
regulation of signal transductionGO:00099662250.087
developmental growthGO:00485891660.084
regulation of macromolecule metabolic processGO:00602553170.084
Human
heterocycle biosynthetic processGO:00181302150.082
Human
digestive tract morphogenesisGO:00485462310.082
regulation of biosynthetic processGO:00098892500.082
Human
response to chemicalGO:00422213200.077
heterocycle metabolic processGO:00464832900.075
Human
cellular component movementGO:00069283350.074
localization of cellGO:00516742440.073
epithelial cell differentiationGO:00308551160.072
determination of left right symmetryGO:00073681790.072
cell projection morphogenesisGO:00488582440.072
microtubule based movementGO:0007018330.071
negative regulation of cellular processGO:00485232830.071
positive regulation of cellular processGO:00485222010.070
Human
larval developmentGO:000216420.070
regulation of rna biosynthetic processGO:20011412130.069
Human
locomotionGO:00400113130.069
Worm
rna biosynthetic processGO:00327741810.066
Human
maintenance of locationGO:005123540.065
organic cyclic compound biosynthetic processGO:19013622230.064
Human
regulation of developmental processGO:00507932470.064
cellular nitrogen compound biosynthetic processGO:00442712180.063
Human
regulation of multicellular organismal processGO:00512392770.063
extrinsic apoptotic signaling pathwayGO:009719130.063
generation of neuronsGO:00486993850.062
dorsal ventral pattern formationGO:00099531250.061
nucleobase containing compound metabolic processGO:00061392740.060
Human
nucleobase containing compound biosynthetic processGO:00346542050.060
Human
cell motilityGO:00488702440.059
regulation of cell communicationGO:00106462320.059
nucleic acid metabolic processGO:00903042440.058
Human
cell morphogenesisGO:00009022890.057
positive regulation of cell cycleGO:004578730.056
cellular component morphogenesisGO:00329893360.056
regulation of cytokine productionGO:000181730.056
compound eye developmentGO:004874920.055
ameboidal type cell migrationGO:00016671430.055
positive regulation of cell activationGO:005086710.055
eye developmentGO:00016542770.055
digestive system developmentGO:00551232890.055
cell cycleGO:0007049930.055
response to external stimulusGO:00096052640.053
protein localization to nucleusGO:003450430.053
positive regulation of cellular component biogenesisGO:004408930.053
cell migrationGO:00164772370.053
organic cyclic compound metabolic processGO:19013603010.053
Human
cellular macromolecule biosynthetic processGO:00346452240.052
Human
cognitionGO:005089010.052
anterior posterior pattern specificationGO:00099521520.051
regulation of nucleic acid templated transcriptionGO:19035062130.051
Human
stem cell divisionGO:001714510.051
sensory organ morphogenesisGO:00905962000.051
regulation of cell differentiationGO:00455951420.051
cell part morphogenesisGO:00329902460.051
carboxylic acid metabolic processGO:0019752220.050
aromatic compound biosynthetic processGO:00194382170.050
Human
vasculature developmentGO:00019442780.049
positive regulation of biological processGO:00485182530.049
Human
female sex differentiationGO:004666040.048
blood vessel developmentGO:00015682460.048
cilium movementGO:0003341260.048
heart loopingGO:0001947940.048
microtubule based processGO:0007017600.048
positive regulation of nitrogen compound metabolic processGO:0051173690.048
Human
adult behaviorGO:003053420.048
regulation of reactive oxygen species metabolic processGO:200037720.047
cilium assemblyGO:0042384580.047
regulation of peptidyl tyrosine phosphorylationGO:005073010.046
cellular protein catabolic processGO:004425740.046
somitogenesisGO:0001756870.046
non canonical wnt signaling pathwayGO:0035567130.046
cellular protein metabolic processGO:00442671290.046
Human Yeast
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.046
embryonic organ developmentGO:00485683810.045
cell projection organizationGO:00300302840.045
regulation of cellular ketone metabolic processGO:001056570.045
regulation of cellular amino acid metabolic processGO:000652100.044
cellular amino acid metabolic processGO:000652070.044
embryonic heart tube morphogenesisGO:00031431080.044
single organism localizationGO:19025782250.043
enzyme linked receptor protein signaling pathwayGO:00071671060.043
inner ear developmentGO:00488391260.043
regulation of nitrogen compound metabolic processGO:00511712510.043
Human
regulation of response to nutrient levelsGO:003210710.043
positive regulation of canonical wnt signaling pathwayGO:009026340.042
regulation of response to stimulusGO:00485832690.042
transcription from rna polymerase ii promoterGO:0006366800.042
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.042
organic substance biosynthetic processGO:19015762890.041
Human
cilium morphogenesisGO:0060271850.041
hematopoietic or lymphoid organ developmentGO:00485341910.041
transcription dna templatedGO:00063511810.041
Human
regulation of cellular amine metabolic processGO:003323800.041
oxoacid metabolic processGO:0043436310.041
neuron differentiationGO:00301823530.041
nitrogen compound metabolic processGO:00068073190.041
Human
neuron projection morphogenesisGO:00488121610.040
growthGO:00400071740.040
cellular amine metabolic processGO:004410620.040
positive regulation of transportGO:005105020.040
heart developmentGO:00075073130.040
proteolysis involved in cellular protein catabolic processGO:005160330.039
hemopoiesisGO:00300971830.039
pigment granule transportGO:0051904190.039
nucleic acid templated transcriptionGO:00976591810.039
Human
somatic muscle developmentGO:000752540.039
positive regulation of biosynthetic processGO:0009891680.039
Human
amine metabolic processGO:000930820.038
macromolecule biosynthetic processGO:00090592270.038
Human
pigmentationGO:0043473850.038
neuroblast proliferationGO:000740520.038
phagocytosisGO:000690930.038
positive regulation of cellular metabolic processGO:0031325940.038
Human
nuclear transportGO:005116940.038
regulation of epithelial cell proliferationGO:005067830.038
regulation of anatomical structure morphogenesisGO:00226031300.037
cellular ketone metabolic processGO:0042180110.037
neuron projection developmentGO:00311751800.036
regulation of cellular metabolic processGO:00313233200.036
Human
b cell differentiationGO:003018310.036
intracellular signal transductionGO:0035556850.036
cell morphogenesis involved in differentiationGO:00009041950.036
segmentationGO:0035282970.036
epithelial tube morphogenesisGO:00605621480.036
positive regulation of cellular amine metabolic processGO:003324000.036
regulation of cell activationGO:005086510.036
single organism organelle organizationGO:19025891990.035
regulation of macromolecule biosynthetic processGO:00105562250.035
Human
regulation of nucleobase containing compound metabolic processGO:00192192500.035
Human
embryonic heart tube developmentGO:00350501330.035
response to carbohydrateGO:000974330.035
negative regulation of wnt signaling pathwayGO:0030178300.035
cellular response to organic substanceGO:00713101050.034
lipid storageGO:001991510.034
phosphate containing compound metabolic processGO:00067961080.034
Human Yeast
regulation of wnt signaling pathwayGO:0030111530.033
embryonic organ morphogenesisGO:00485622740.033
regulation of cellular macromolecule biosynthetic processGO:20001122220.033
Human
cellular component biogenesisGO:00440851780.032
positive regulation of cellular amino acid metabolic processGO:004576400.032
regulation of cellular biosynthetic processGO:00313262450.032
Human
adherens junction organizationGO:003433240.032
cellular biosynthetic processGO:00442492860.032
Human
mononuclear cell proliferationGO:003294310.032
modification dependent protein catabolic processGO:001994130.032
regulation of stem cell differentiationGO:200073640.032
response to endogenous stimulusGO:0009719830.032
angiogenesisGO:00015251580.031
nucleocytoplasmic transportGO:000691340.031
regulation of primary metabolic processGO:00800903110.031
Human
protein targeting to nucleusGO:004474430.031
positive regulation of developmental processGO:0051094500.031
inner ear morphogenesisGO:0042472630.030
regulation of nervous system developmentGO:0051960900.030
regulation of protein transportGO:005122330.030
stem cell differentiationGO:00488631170.030
regulation of tube sizeGO:003515020.030
ubiquitin dependent protein catabolic processGO:000651130.030
organelle localizationGO:0051640490.030
positive regulation of epithelial cell differentiationGO:003085820.029
melanosome transportGO:0032402190.029
negative regulation of response to stimulusGO:00485851040.029
axonogenesisGO:00074091520.029
regulation of rna metabolic processGO:00512522240.029
Human
response to organic substanceGO:00100331530.029
female gonad developmentGO:000858540.029
regulation of extrinsic apoptotic signaling pathwayGO:200123630.029
determination of heart left right asymmetryGO:00613711170.029
regulation of cell developmentGO:00602841000.029
response to stressGO:00069502630.029
protein metabolic processGO:00195381830.028
Human Yeast
positive regulation of map kinase activityGO:004340630.028
nonmotile primary cilium assemblyGO:003505820.028
canonical wnt signaling pathwayGO:0060070480.028
ear developmentGO:00435831270.028
tube closureGO:006060610.028
agingGO:000756820.028
regulation of transcription dna templatedGO:00063552130.028
Human
transportGO:00068102200.028
system processGO:00030081850.028
mediolateral intercalationGO:006003130.027
modification dependent macromolecule catabolic processGO:004363230.027
cellular component assemblyGO:00226071700.027
embryonic pattern specificationGO:0009880440.027
periodic partitioningGO:000736510.027
regulation of transcription from rna polymerase ii promoterGO:00063571140.027
regulation of synapse organizationGO:005080730.027
response to monosaccharideGO:003428430.027
response to drugGO:004249330.027
hepaticobiliary system developmentGO:0061008980.027
ovulation cycleGO:004269820.027
regulation of biological qualityGO:00650082630.027
development of primary female sexual characteristicsGO:004654540.026
stem cell developmentGO:0048864820.026
neuron developmentGO:00486662620.026
cilium organizationGO:0044782710.026
chemosensory behaviorGO:000763510.026
negative regulation of signal transductionGO:0009968940.026
biosynthetic processGO:00090582940.026
Human
positive regulation of transcription dna templatedGO:0045893570.026
Human
lateral line system developmentGO:0048925760.026
smooth muscle contractionGO:000693920.026
positive regulation of rna metabolic processGO:0051254590.026
Human
positive regulation of protein kinase b signalingGO:005189710.026
gland developmentGO:00487321430.025
positive regulation of cytosolic calcium ion concentrationGO:000720440.025
chordate embryonic developmentGO:00430092710.025
regulation of synapse assemblyGO:005196330.025
regulation of axonogenesisGO:0050770320.025
leukocyte proliferationGO:007066110.025
organic acid metabolic processGO:0006082310.025
cytokinesisGO:000091030.025
notch signaling pathwayGO:0007219350.025
synaptic target recognitionGO:000803910.025
blood vessel morphogenesisGO:00485142160.025
cell morphogenesis involved in neuron differentiationGO:00486671630.025
segment polarity determinationGO:000736710.024
establishment of localizationGO:00512342440.024
regulation of jak stat cascadeGO:004642530.024
positive regulation of stress activated mapk cascadeGO:003287430.024
germ line stem cell maintenanceGO:003071820.024
regulation of response to extracellular stimulusGO:003210410.024
cellular modified amino acid metabolic processGO:000657530.024
microtubule organizing center organizationGO:003102310.024
positive regulation of gene expressionGO:0010628710.024
Human
cilium or flagellum dependent cell motilityGO:000153940.024
deathGO:00162651210.024
single organism nuclear importGO:190259330.024
positive regulation of immune effector processGO:000269930.024
regulation of inflammatory responseGO:005072720.024
regulation of canonical wnt signaling pathwayGO:0060828340.023
negative regulation of metabolic processGO:0009892860.023
regulation of neurogenesisGO:0050767870.023
fin regenerationGO:0031101510.023
positive regulation of cellular biosynthetic processGO:0031328680.023
Human
lymphocyte proliferationGO:004665110.023
response to woundingGO:00096111160.023
heart morphogenesisGO:00030071560.023
response to biotic stimulusGO:0009607970.023
response to glucoseGO:000974930.023
establishment of protein localization to organelleGO:007259440.023
cell migration involved in gastrulationGO:0042074790.023
regulation of localizationGO:00328791040.023
establishment of pigment granule localizationGO:0051905220.022
small molecule metabolic processGO:0044281770.022
cellular protein modification processGO:00064641000.022
Human Yeast
single organism transportGO:00447652060.022
wound healingGO:0042060900.022
connective tissue developmentGO:0061448990.022
Human
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.022
positive regulation of catabolic processGO:000989640.022
somatic stem cell maintenanceGO:003501910.022
regulation of apoptotic processGO:0042981980.022
organelle organizationGO:00069962270.022
regulation of protein modification by small protein conjugation or removalGO:190332030.022
negative regulation of cell communicationGO:0010648960.022
immune system developmentGO:00025201910.022
otic vesicle formationGO:0030916270.022
regulation of establishment of planar polarityGO:009017540.022
forebrain developmentGO:0030900960.022
kidney developmentGO:0001822920.022
response to hexoseGO:000974630.021
protein secretionGO:000930610.021
b cell activationGO:004211320.021
negative regulation of protein phosphorylationGO:000193340.021
rhombomere 5 developmentGO:002157140.021
superoxide metabolic processGO:000680120.021
regulation of neuron differentiationGO:0045664560.021
stem cell proliferationGO:007208940.021
somite developmentGO:0061053960.021
camera type eye developmentGO:00430102220.021
positive regulation of multicellular organismal processGO:0051240520.021
centrosome organizationGO:005129710.021
establishment of vesicle localizationGO:0051650240.021
gastrulation with mouth forming secondGO:0001702440.021
positive regulation of jnk cascadeGO:004633030.021
negative regulation of catabolic processGO:000989530.021
tissue remodelingGO:004877140.021
single organism metabolic processGO:00447102170.021
positive regulation of epithelial cell migrationGO:001063420.021
protein modification processGO:00362111000.021
Human Yeast
positive regulation of response to stimulusGO:0048584800.021
negative regulation of gene expressionGO:0010629650.020
regulation of establishment of protein localizationGO:007020140.020
cellular localizationGO:0051641970.020
dorsal convergenceGO:0060030140.020
cellular response to molecule of bacterial originGO:007121930.020
establishment of melanosome localizationGO:0032401190.020
regulation of bindingGO:005109830.020
ectodermal placode morphogenesisGO:0071697320.020
response to growth factorGO:0070848390.020
regulation of cell deathGO:00109411030.020
regulation of leukocyte mediated immunityGO:000270310.020
cellular response to endogenous stimulusGO:0071495680.020
protein importGO:001703830.020
programmed cell deathGO:00125011190.019
regulation of organ growthGO:004662030.019
positive regulation of macromolecule biosynthetic processGO:0010557590.019
Human
tissue regenerationGO:0042246740.019
exocytosisGO:000688710.019
negative regulation of protein serine threonine kinase activityGO:007190120.019
immune system processGO:00023762410.019
taxisGO:00423301090.019
protein heterooligomerizationGO:005129110.018
homeostatic processGO:00425921420.018
negative regulation of developmental processGO:0051093650.018
regulation of reproductive processGO:200024140.018
positive regulation of nucleobase containing compound metabolic processGO:0045935690.018
Human
macromolecule modificationGO:00434121110.018
Human Yeast
regulation of cell projection assemblyGO:006049140.018
sensory system developmentGO:0048880760.018
myeloid cell differentiationGO:0030099860.018
startle responseGO:000196440.018
signal transduction in absence of ligandGO:003803410.018
regulation of dna replicationGO:000627530.018
negative regulation of epithelial cell proliferationGO:005068010.018
cellular aromatic compound metabolic processGO:00067252950.018
Human
neuromast developmentGO:0048884460.018
primary neural tube formationGO:001402010.018
cell deathGO:00082191210.017
mitotic cell cycle processGO:1903047480.017
pigment granule localizationGO:0051875250.017
positive regulation of cell adhesionGO:004578510.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.017
negative regulation of kinase activityGO:003367340.017
liver developmentGO:0001889960.017
positive regulation of cytokine productionGO:000181920.017
formation of primary germ layerGO:0001704620.017
regulation of cytoplasmic transportGO:190364940.017
positive regulation of cell communicationGO:0010647560.017
regulation of wound healingGO:006104120.017
regulation of meiotic cell cycleGO:005144510.017
positive regulation of cellular catabolic processGO:003133130.017
mitotic cell cycleGO:0000278640.017
cellular carbohydrate metabolic processGO:004426240.017
inositol lipid mediated signalingGO:004801720.017
apoptotic processGO:00069151160.017
regulation of protein catabolic processGO:004217610.017
jak stat cascadeGO:000725950.017
determination of ventral identityGO:0048264210.017
developmental pigmentationGO:0048066480.017
negative regulation of nuclear divisionGO:005178430.017
response to abiotic stimulusGO:00096281220.016
phosphatidylinositol 3 kinase signalingGO:001406520.016
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.016
sequestering of metal ionGO:005123830.016
erythrocyte homeostasisGO:0034101550.016
nuclear importGO:005117030.016
cellular response to lipopolysaccharideGO:007122230.016
pancreas developmentGO:0031016840.016
osteoclast differentiationGO:003031610.016
positive regulation of leukocyte mediated immunityGO:000270510.016
negative regulation of protein kinase activityGO:000646940.016
response to virusGO:0009615210.016
sensory perception of chemical stimulusGO:000760630.016
regulation of programmed cell deathGO:00430671010.016
cellular response to chemical stimulusGO:00708871570.016
axon developmentGO:00615641660.016
regulation of purine nucleotide catabolic processGO:003312120.016
telencephalon developmentGO:0021537140.016
endosomal transportGO:001619720.016
release of sequestered calcium ion into cytosolGO:005120930.016
rhombomere 6 developmentGO:002157240.016
phosphatidylinositol mediated signalingGO:004801520.015
regulation of cell morphogenesis involved in differentiationGO:0010769380.015
positive regulation of cell divisionGO:005178120.015
positive regulation of jun kinase activityGO:004350720.015
muscle structure developmentGO:00610611960.015
Mouse
tyrosine phosphorylation of stat proteinGO:000726010.015
regenerationGO:0031099910.015
macromolecular complex disassemblyGO:003298410.015
positive regulation of jak stat cascadeGO:004642720.015
negative regulation of synapse assemblyGO:005196420.015
regulation of cell motilityGO:2000145460.015
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.015
response to other organismGO:0051707970.015
positive regulation of notch signaling pathwayGO:004574730.015
positive regulation of blood circulationGO:190352420.015
positive regulation of cell killingGO:003134320.015
negative regulation of cellular catabolic processGO:003133030.015
skeletal system developmentGO:00015011810.015
oocyte maturationGO:000155640.015
cellular response to growth factor stimulusGO:0071363390.015
organonitrogen compound metabolic processGO:1901564740.015
histone deacetylationGO:001657520.015
regulation of blood pressureGO:000821710.015
glial cell migrationGO:000834730.015
otic vesicle morphogenesisGO:0071600340.015
erk1 and erk2 cascadeGO:007037140.015
myeloid leukocyte differentiationGO:0002573150.015
regulation of dendrite developmentGO:005077330.015
developmental growth involved in morphogenesisGO:0060560860.015
cell proliferationGO:0008283800.015
wnt signaling pathway planar cell polarity pathwayGO:006007140.015
calcium ion transport into cytosolGO:006040230.015
astrocyte differentiationGO:004870810.014
urogenital system developmentGO:0001655970.014
negative regulation of stem cell differentiationGO:200073720.014
regulation of cellular component organizationGO:0051128860.014
spermatid developmentGO:000728620.014
regulation of developmental growthGO:0048638380.014
positive regulation of dna metabolic processGO:005105410.014
negative regulation of multicellular organismal processGO:0051241690.014
maternal determination of anterior posterior axis embryoGO:000835840.014
axis elongationGO:0003401310.014
protein import into nucleusGO:000660630.014
carbohydrate biosynthetic processGO:001605110.014
fin developmentGO:0033333770.014
specification of organ identityGO:001009220.014
regulation of cell shapeGO:000836010.014
cartilage developmentGO:0051216960.014
protein kinase b signalingGO:004349190.014
spermatid differentiationGO:004851520.014
regulation of jun kinase activityGO:004350630.014
establishment of localization in cellGO:0051649770.014
cilium movement involved in cell motilityGO:006029430.014
post embryonic organ developmentGO:004856940.014
negative regulation of cellular metabolic processGO:0031324770.014
cell killingGO:000190620.014
negative regulation of programmed cell deathGO:0043069580.014
negative regulation of nitrogen compound metabolic processGO:0051172590.014
epithelial cell developmentGO:0002064420.014
lipid metabolic processGO:0006629520.014
cytoskeleton organizationGO:0007010960.014
negative regulation of map kinase activityGO:004340720.013
regulation of protein bindingGO:004339330.013
regulation of mrna processingGO:005068430.013
lateral inhibitionGO:004633110.013
regulation of nucleotide catabolic processGO:003081120.013
establishment of organelle localizationGO:0051656450.013
positive regulation of purine nucleotide catabolic processGO:003312310.013
muscle cell migrationGO:001481240.013
negative regulation of mesodermal cell fate specificationGO:004266230.013
cellular response to biotic stimulusGO:007121630.013
cell cycle processGO:0022402530.013
otic vesicle developmentGO:0071599420.013
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.013
determination of dorsal ventral asymmetryGO:0048262340.013
regulation of cell morphogenesisGO:0022604420.013
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.013
bmp signaling pathwayGO:0030509520.013
cellular response to extracellular stimulusGO:003166820.013
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.013
eye morphogenesisGO:00485921440.013
ras protein signal transductionGO:000726570.013
myeloid cell developmentGO:0061515320.013
ear morphogenesisGO:0042471640.013
regulation of wnt signaling pathway planar cell polarity pathwayGO:200009520.013
negative regulation of dna metabolic processGO:005105340.013
positive regulation of rna biosynthetic processGO:1902680570.013
Human
regulation of sequestering of calcium ionGO:005128240.013
regulation of alternative mrna splicing via spliceosomeGO:000038110.013
response to oxygen containing compoundGO:1901700550.013
regulation of neuron projection developmentGO:0010975400.013
gtp metabolic processGO:004603940.013
otic placode formationGO:0043049230.013

dyrk1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
bone diseaseDOID:008000100.041
connective tissue diseaseDOID:6500.041
disease of anatomical entityDOID:700.041
Human
musculoskeletal system diseaseDOID:1700.041
disease of cellular proliferationDOID:1456600.028
cancerDOID:16200.028
organ system cancerDOID:005068600.028
disease of metabolismDOID:001466700.017
bone development diseaseDOID:008000600.015