Danio rerio

0 known processes

lck

lymphocyte-specific protein tyrosine kinase

(Aliases: MGC194004,zgc:136695,MGC194043,MGC136695)

lck biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
t cell differentiationGO:003021760.100
Human Mouse
regulation of synapse assemblyGO:005196330.084
Fly
nitrogen compound metabolic processGO:00068073190.078
morphogenesis of an epitheliumGO:00020093330.077
Zebrafish Fly
cellular component movementGO:00069283350.072
Worm Fly
cell fate commitmentGO:0045165990.071
Worm
rna metabolic processGO:00160702190.065
tube morphogenesisGO:00352393490.060
Zebrafish Worm
larval developmentGO:000216420.056
agingGO:000756820.056
ameboidal type cell migrationGO:00016671430.053
maintenance of locationGO:005123540.052
Mouse
endosomal transportGO:001619720.050
locomotionGO:00400113130.047
Worm Fly
muscle structure developmentGO:00610611960.047
cellular nitrogen compound metabolic processGO:00346412900.045
rna localizationGO:000640340.045
regulation of synapse organizationGO:005080730.044
Fly
cellular ketone metabolic processGO:0042180110.043
oocyte anterior posterior axis specificationGO:000731440.043
small molecule metabolic processGO:0044281770.042
neuron differentiationGO:00301823530.041
Fly
immune system developmentGO:00025201910.040
Human Mouse
endoderm developmentGO:0007492490.040
Worm
organic cyclic compound biosynthetic processGO:19013622230.040
heterocycle biosynthetic processGO:00181302150.040
cellular aromatic compound metabolic processGO:00067252950.039
hemopoiesisGO:00300971830.039
Human Mouse
skeletal muscle organ developmentGO:0060538780.038
calcium mediated signalingGO:001972220.038
nucleobase containing compound metabolic processGO:00061392740.037
regulation of synaptic growth at neuromuscular junctionGO:000858210.037
Fly
olfactory lobe developmentGO:002198840.037
brain developmentGO:00074202930.035
Fly
pole plasm assemblyGO:000731540.035
cell motilityGO:00488702440.034
Worm
stem cell maintenanceGO:001982740.034
positive regulation of camp biosynthetic processGO:003081920.034
cytoplasm organizationGO:000702840.033
dorsal ventral pattern formationGO:00099531250.032
central nervous system developmentGO:00074173870.032
Fly
cell morphogenesisGO:00009022890.032
Fly
determination of bilateral symmetryGO:00098552040.031
regulation of tyrosine phosphorylation of stat proteinGO:004250910.031
Mouse
mesenchymal cell differentiationGO:0048762870.031
regulation of cellular amino acid metabolic processGO:000652100.031
aromatic compound biosynthetic processGO:00194382170.031
gastrulationGO:00073692080.030
Zebrafish Worm
specification of symmetryGO:00097992040.030
embryonic heart tube developmentGO:00350501330.030
response to virusGO:0009615210.029
muscle cell differentiationGO:00426921390.029
multi organism processGO:00517041340.029
Zebrafish Fly
cell projection morphogenesisGO:00488582440.028
Fly
phagocytosisGO:000690930.028
striated muscle tissue developmentGO:00147061100.028
phosphatidylinositol mediated signalingGO:004801520.028
chemosensory behaviorGO:000763510.027
Fly
intracellular mrna localizationGO:000829810.027
secondary metabolic processGO:001974830.027
cell migration involved in gastrulationGO:0042074790.027
guanosine containing compound metabolic processGO:190106840.026
tyrosine phosphorylation of stat proteinGO:000726010.026
Mouse
muscle organ developmentGO:00075171010.026
adherens junction organizationGO:003433240.026
Fly
organic cyclic compound metabolic processGO:19013603010.026
stem cell developmentGO:0048864820.026
heart developmentGO:00075073130.025
sleepGO:003043110.025
digestive tract morphogenesisGO:00485462310.025
Zebrafish Worm
digestive tract developmentGO:00485652650.025
Zebrafish Worm
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.025
regulation of reproductive processGO:200024140.025
melanin metabolic processGO:000658220.025
lamellipodium assemblyGO:003003210.024
cell migrationGO:00164772370.024
Worm
response to external biotic stimulusGO:0043207970.024
Zebrafish
organonitrogen compound metabolic processGO:1901564740.024
nucleic acid metabolic processGO:00903042440.024
cell part morphogenesisGO:00329902460.023
Fly
regionalizationGO:00030022740.023
Zebrafish
response to other organismGO:0051707970.023
Zebrafish
phosphatidylinositol 3 kinase signalingGO:001406520.023
maternal determination of anterior posterior axis embryoGO:000835840.023
regulation of rna metabolic processGO:00512522240.022
regulation of cellular biosynthetic processGO:00313262450.022
cell morphogenesis involved in differentiationGO:00009041950.022
Fly
phagocytosis engulfmentGO:000691110.022
positive regulation of catabolic processGO:000989640.022
internal protein amino acid acetylationGO:000647520.022
organic substance biosynthetic processGO:19015762890.022
positive regulation of camp metabolic processGO:003081620.022
embryonic organ developmentGO:00485683810.022
protein acetylationGO:000647320.022
regulation of multicellular organism growthGO:004001440.021
multicellular organism growthGO:003526440.021
b cell differentiationGO:003018310.021
heterocycle metabolic processGO:00464832900.021
gene expressionGO:00104672520.021
Human Mouse
cellular response to external stimulusGO:007149620.021
regulation of nucleobase containing compound metabolic processGO:00192192500.021
regulation of cell shapeGO:000836010.021
cellular macromolecule metabolic processGO:00442603910.020
Human Zebrafish Mouse Worm Fly
positive regulation of purine nucleotide biosynthetic processGO:190037380.020
protein localization to nucleusGO:003450430.020
energy homeostasisGO:009700930.020
actin polymerization or depolymerizationGO:000815420.020
Fly
gtp metabolic processGO:004603940.020
transcription from rna polymerase ii promoterGO:0006366800.020
positive regulation of myeloid cell differentiationGO:004563920.020
hematopoietic or lymphoid organ developmentGO:00485341910.019
Human Mouse
immune system processGO:00023762410.019
Human Mouse
lamellipodium organizationGO:009758110.019
regulation of bindingGO:005109830.019
positive regulation of reproductive processGO:200024320.019
mesenchyme developmentGO:00604851270.019
negative regulation of synapse assemblyGO:005196420.019
Fly
regulation of biosynthetic processGO:00098892500.019
regulation of cellular amine metabolic processGO:003323800.019
neuron projection developmentGO:00311751800.019
Fly
regulation of metabolic processGO:00192223590.018
Human Zebrafish Mouse Fly
cellular biosynthetic processGO:00442492860.018
multicellular organismal homeostasisGO:0048871290.018
regulation of inflammatory responseGO:005072720.018
regulation of cyclic nucleotide biosynthetic processGO:0030802150.018
cell projection organizationGO:00300302840.018
Fly
internal peptidyl lysine acetylationGO:001839320.018
energy reserve metabolic processGO:000611220.018
determination of dorsal ventral asymmetryGO:0048262340.017
centrosome cycleGO:000709810.017
lipid homeostasisGO:005508830.017
cell agingGO:000756920.017
regulation of cell activationGO:005086510.017
Human Mouse
cellular component morphogenesisGO:00329893360.017
Fly
cyclic nucleotide biosynthetic processGO:0009190180.017
positive regulation of nucleobase containing compound metabolic processGO:0045935690.017
rna biosynthetic processGO:00327741810.017
meiotic cell cycle processGO:190304630.017
regulation of cell substrate adhesionGO:001081010.017
rna transportGO:005065820.017
spermatid differentiationGO:004851520.017
head developmentGO:00603223030.017
Fly
nuclear transportGO:005116940.017
regulation of cellular ketone metabolic processGO:001056570.016
regulation of signalingGO:00230512350.016
Human Zebrafish Mouse
neuron projection morphogenesisGO:00488121610.016
Fly
positive regulation of cytosolic calcium ion concentrationGO:000720440.016
Mouse
neuroblast proliferationGO:000740520.016
protein localization to cell surfaceGO:003439430.016
cortical actin cytoskeleton organizationGO:003086610.016
negative regulation of defense responseGO:003134820.016
cellular amine metabolic processGO:004410620.016
positive regulation of cellular processGO:00485222010.016
Human Mouse Fly
regulation of circadian sleep wake cycle sleepGO:004518710.016
glial cell migrationGO:000834730.016
regulation of transcription from rna polymerase ii promoterGO:00063571140.016
hormone secretionGO:004687920.016
eye developmentGO:00016542770.016
protein complex disassemblyGO:004324110.016
cytokinesisGO:000091030.015
regulation of signal transductionGO:00099662250.015
Human Zebrafish Mouse
mononuclear cell proliferationGO:003294310.015
regulation of establishment of protein localizationGO:007020140.015
compound eye developmentGO:004874920.015
regulation of nitrogen compound metabolic processGO:00511712510.015
positive regulation of cellular catabolic processGO:003133130.015
regulation of tyrosine phosphorylation of stat3 proteinGO:004251610.015
peptidyl lysine acetylationGO:001839420.015
centrosome organizationGO:005129710.015
response to stressGO:00069502630.015
positive regulation of protein polymerizationGO:003227320.015
developmental maturationGO:0021700340.015
regulation of macromolecule metabolic processGO:00602553170.015
Human Zebrafish Mouse Fly
striated muscle cell differentiationGO:00511461290.015
positive regulation of macromolecule biosynthetic processGO:0010557590.015
dicarboxylic acid transportGO:000683510.015
positive regulation of multi organism processGO:004390230.015
female gonad developmentGO:000858540.015
gtp catabolic processGO:000618420.014
defense response to fungusGO:005083220.014
regulation of cell projection assemblyGO:006049140.014
actin filament polymerizationGO:003004120.014
positive regulation of nitrogen compound metabolic processGO:0051173690.014
ventricular cardiac muscle tissue morphogenesisGO:005501020.014
lens fiber cell morphogenesisGO:007030930.014
positive regulation of cytoskeleton organizationGO:005149530.014
regulation of cytokine productionGO:000181730.014
protein importGO:001703830.014
response to biotic stimulusGO:0009607970.014
Zebrafish
macromolecular complex disassemblyGO:003298410.014
apoptotic process involved in developmentGO:190274220.014
synaptic growth at neuromuscular junctionGO:005112420.014
Fly
rhombomere 5 developmentGO:002157140.014
regulation of cell developmentGO:00602841000.014
regulation of gene expressionGO:00104682650.014
Mouse
adherens junction maintenanceGO:003433420.014
endocrine processGO:005088620.014
retinal rod cell developmentGO:004654840.014
somatic cell dna recombinationGO:001644410.014
spindle assemblyGO:005122520.013
biosynthetic processGO:00090582940.013
sensory perception of chemical stimulusGO:000760630.013
negative regulation of reproductive processGO:200024230.013
modification dependent macromolecule catabolic processGO:004363230.013
regulation of neural precursor cell proliferationGO:200017730.013
membrane fusionGO:006102520.013
proteolysis involved in cellular protein catabolic processGO:005160330.013
macromolecule biosynthetic processGO:00090592270.013
response to alkaloidGO:004327920.013
carbohydrate derivative metabolic processGO:1901135610.013
regulation of blood pressureGO:000821710.013
striated muscle cell developmentGO:00550021080.013
atp catabolic processGO:000620040.013
regulation of histone methylationGO:003106030.013
adult behaviorGO:003053420.013
embryonic heart tube morphogenesisGO:00031431080.013
central nervous system neuron differentiationGO:0021953740.013
regulation of peptidyl tyrosine phosphorylationGO:005073010.013
Mouse
meiotic nuclear divisionGO:000712640.013
cell morphogenesis involved in neuron differentiationGO:00486671630.013
Fly
establishment of rna localizationGO:005123630.013
positive regulation of histone modificationGO:003105810.013
segmentationGO:0035282970.013
meiotic chromosome segregationGO:004513230.013
cellular response to extracellular stimulusGO:003166820.013
organelle assemblyGO:00709251100.013
regulation of rna biosynthetic processGO:20011412130.013
regulation of cellular component organizationGO:0051128860.013
Fly
regulation of dendrite morphogenesisGO:004881430.013
response to uvGO:000941130.013
regulation of mrna processingGO:005068430.013
purine ribonucleoside monophosphate catabolic processGO:000916940.013
generation of neuronsGO:00486993850.013
Fly
dna catabolic processGO:000630810.013
ventricular cardiac muscle tissue developmentGO:000322930.012
tyrosine phosphorylation of stat3 proteinGO:004250310.012
epithelial cell morphogenesisGO:000338220.012
growthGO:00400071740.012
Fly
positive regulation of cellular amino acid metabolic processGO:004576400.012
b cell activationGO:004211320.012
protein localization to plasma membraneGO:007265910.012
positive regulation of transportGO:005105020.012
negative regulation of protein phosphorylationGO:000193340.012
g protein coupled receptor signaling pathwayGO:0007186740.012
olfactory bulb developmentGO:002177240.012
organelle organizationGO:00069962270.012
Worm Fly
positive regulation of translationGO:004572710.012
development of primary female sexual characteristicsGO:004654540.012
cellular monovalent inorganic cation homeostasisGO:003000420.012
protein acylationGO:004354330.012
response to drugGO:004249330.012
Human
embryo development ending in birth or egg hatchingGO:00097922710.012
Worm
nucleic acid templated transcriptionGO:00976591810.012
positive regulation of cyclic nucleotide biosynthetic processGO:003080480.012
ribosomal small subunit biogenesisGO:004227420.012
positive regulation of muscle organ developmentGO:004863610.012
centrosome duplicationGO:005129810.012
negative regulation of histone modificationGO:003105710.012
peptide transportGO:001583310.012
regulation of phGO:000688530.012
positive regulation of striated muscle cell differentiationGO:005115510.012
photoreceptor cell fate commitmentGO:004655210.012
embryonic organ morphogenesisGO:00485622740.012
ubiquitin dependent protein catabolic processGO:000651130.012
symbiosis encompassing mutualism through parasitismGO:004440340.012
cellular response to nutrient levelsGO:003166920.012
interspecies interaction between organismsGO:004441940.012
nucleocytoplasmic transportGO:000691340.012
regulation of cellular metabolic processGO:00313233200.012
Human Zebrafish Mouse Fly
amino acid transportGO:000686520.012
leukocyte activationGO:0045321120.011
Human Mouse
tissue remodelingGO:004877140.011
regulation of cytoplasmic transportGO:190364940.011
cortical cytoskeleton organizationGO:003086510.011
catechol containing compound metabolic processGO:000971220.011
single organism organelle organizationGO:19025891990.011
Worm Fly
regulation of skeletal muscle fiber developmentGO:004874220.011
cellular nitrogen compound biosynthetic processGO:00442712180.011
regulation of blood vessel sizeGO:005088020.011
rna 3 end processingGO:003112320.011
lateral inhibitionGO:004633110.011
single organism membrane fusionGO:004480120.011
modification dependent protein catabolic processGO:001994130.011
stem cell differentiationGO:00488631170.011
nuclear exportGO:005116810.011
regulation of nucleoside metabolic processGO:000911820.011
heart loopingGO:0001947940.011
leukocyte proliferationGO:007066110.011
cellular macromolecule biosynthetic processGO:00346452240.011
spermatid developmentGO:000728620.011
negative regulation of mrna processingGO:005068610.011
ribonucleoside monophosphate catabolic processGO:000915840.011
somatic muscle developmentGO:000752540.011
mitochondrion organizationGO:000700540.011
cell fate commitment involved in formation of primary germ layerGO:0060795260.011
Worm
nucleic acid transportGO:005065720.011
camp biosynthetic processGO:0006171110.011
glial cell proliferationGO:001400940.011
leukocyte homeostasisGO:000177620.011
transcription dna templatedGO:00063511810.011
single organism nuclear importGO:190259330.011
embryonic pattern specificationGO:0009880440.011
positive regulation of metabolic processGO:00098931080.011
Human Mouse Fly
sensory perception of smellGO:000760820.011
single organism metabolic processGO:00447102170.011
macroautophagyGO:001623610.011
establishment of protein localization to plasma membraneGO:009000210.011
regulation of dendrite developmentGO:005077330.011
positive regulation of nucleoside metabolic processGO:004597910.011
connective tissue developmentGO:0061448990.011
microtubule cytoskeleton organization involved in mitosisGO:190285010.011
dna biosynthetic processGO:007189730.011
regulation of protein transportGO:005122330.011
ketone biosynthetic processGO:004218120.011
regulation of meiotic cell cycleGO:005144510.011
carbohydrate homeostasisGO:003350010.011
regulation of muscle contractionGO:000693730.010
negative regulation of chromosome organizationGO:200125110.010
positive regulation of cell cycleGO:004578730.010
lymphocyte proliferationGO:004665110.010
negative regulation of protein complex assemblyGO:003133310.010
regulation of protein localization to nucleusGO:190018020.010
myofibril assemblyGO:0030239480.010
positive regulation of epithelial cell proliferationGO:005067910.010
organelle fusionGO:004828430.010
mesenchymal cell developmentGO:0014031780.010
stem cell proliferationGO:007208940.010
axon developmentGO:00615641660.010
Fly
regulation of wound healingGO:006104120.010
carboxylic acid metabolic processGO:0019752220.010
cellular component assembly involved in morphogenesisGO:00109271070.010
regulation of nucleic acid templated transcriptionGO:19035062130.010
golgi vesicle transportGO:004819330.010
negative regulation of multi organism processGO:004390130.010
positive regulation of cellular component biogenesisGO:004408930.010
response to carbohydrateGO:000974330.010
intracellular signal transductionGO:0035556850.010
Human Mouse
cell junction maintenanceGO:003433120.010
endocrine hormone secretionGO:006098620.010
developmental programmed cell deathGO:001062340.010
nucleoside monophosphate catabolic processGO:000912540.010
negative regulation of cytoplasmic transportGO:190365020.010
epidermis developmentGO:0008544480.010
negative regulation of protein kinase activityGO:000646940.010

lck disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.020
nervous system diseaseDOID:86300.020
eye diseaseDOID:561400.018
sensory system diseaseDOID:005015500.018
eye and adnexa diseaseDOID:149200.018
retinal degenerationDOID:846600.018
retinal diseaseDOID:567900.018
musculoskeletal system diseaseDOID:1700.012
connective tissue diseaseDOID:6500.012
bone diseaseDOID:008000100.012
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.011
organ system cancerDOID:005068600.011