Danio rerio

73 known processes

fktn

fukutin

(Aliases: im:7163166,zgc:162828,fcmd,MGC162828)

fktn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
glycosylationGO:0070085110.988
macromolecule glycosylationGO:004341390.961
protein glycosylationGO:000648690.943
carbohydrate derivative biosynthetic processGO:1901137430.903
protein o linked glycosylationGO:000649340.833
regulation of protein glycosylationGO:006004930.824
glycoprotein biosynthetic processGO:0009101210.779
striated muscle cell differentiationGO:00511461290.622
mannosylationGO:009750230.529
regulation of biological qualityGO:00650082630.327
homeostatic processGO:00425921420.266
determination of heart left right asymmetryGO:00613711170.241
determination of bilateral symmetryGO:00098552040.232
anatomical structure homeostasisGO:0060249360.228
regulation of carbohydrate metabolic processGO:000610940.201
single organism carbohydrate metabolic processGO:0044723120.198
blood vessel developmentGO:00015682460.167
carbohydrate metabolic processGO:0005975120.163
regulation of glycoprotein biosynthetic processGO:001055930.154
glycoprotein metabolic processGO:0009100230.139
regulation of biosynthetic processGO:00098892500.136
organic substance biosynthetic processGO:19015762890.131
extracellular matrix organizationGO:0030198270.130
muscle structure developmentGO:00610611960.128
muscle tissue developmentGO:00605371100.126
cellular component movementGO:00069283350.124
morphogenesis of an epitheliumGO:00020093330.120
regulation of synaptic growth at neuromuscular junctionGO:000858210.118
positive regulation of cytokine productionGO:000181920.118
determination of left right symmetryGO:00073681790.114
cellular macromolecule biosynthetic processGO:00346452240.109
regulation of primary metabolic processGO:00800903110.107
regulation of cellular carbohydrate metabolic processGO:001067540.104
regulation of synapse organizationGO:005080730.090
macromolecule biosynthetic processGO:00090592270.087
cell growthGO:0016049570.086
striated muscle cell developmentGO:00550021080.085
cellular biosynthetic processGO:00442492860.085
ameboidal type cell migrationGO:00016671430.085
response to stressGO:00069502630.084
cognitionGO:005089010.083
cellular carbohydrate metabolic processGO:004426240.082
regulation of cellular macromolecule biosynthetic processGO:20001122220.082
response to chemicalGO:00422213200.081
embryonic heart tube morphogenesisGO:00031431080.080
protein metabolic processGO:00195381830.079
erythrocyte developmentGO:0048821240.078
negative regulation of kinase activityGO:003367340.078
regulation of cell developmentGO:00602841000.076
polarized epithelial cell differentiationGO:003085940.074
regionalizationGO:00030022740.073
muscle cell differentiationGO:00426921390.072
regulation of synapse assemblyGO:005196330.072
retina morphogenesis in camera type eyeGO:0060042790.071
heterocycle metabolic processGO:00464832900.069
somitogenesisGO:0001756870.066
cellular component morphogenesisGO:00329893360.063
mononuclear cell proliferationGO:003294310.060
muscle cell developmentGO:00550011150.059
embryonic skeletal system developmentGO:0048706970.059
response to hexoseGO:000974630.058
cellular protein metabolic processGO:00442671290.058
striated muscle tissue developmentGO:00147061100.058
kidney developmentGO:0001822920.057
organelle organizationGO:00069962270.056
cellular macromolecule metabolic processGO:00442603910.054
protein mannosylationGO:003526830.054
positive regulation of biological processGO:00485182530.052
regulation of cellular protein metabolic processGO:0032268520.052
regulation of cell morphogenesisGO:0022604420.051
cellular protein modification processGO:00064641000.050
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.050
chordate embryonic developmentGO:00430092710.049
axon extensionGO:0048675450.048
nuclear transportGO:005116940.045
regulation of cellular amine metabolic processGO:003323800.045
specification of symmetryGO:00097992040.044
response to oxygen levelsGO:0070482250.044
regulation of extent of cell growthGO:0061387290.043
dorsal ventral pattern formationGO:00099531250.042
negative regulation of catabolic processGO:000989530.042
positive regulation of cell activationGO:005086710.042
peptidyl threonine modificationGO:001821010.041
negative regulation of nuclear divisionGO:005178430.040
axon midline choice point recognitionGO:001619940.039
erk1 and erk2 cascadeGO:007037140.038
regulation of cytokine productionGO:000181730.038
regulation of bindingGO:005109830.037
heterocycle biosynthetic processGO:00181302150.037
regulation of production of molecular mediator of immune responseGO:000270010.037
single organism metabolic processGO:00447102170.037
regulation of collateral sprouting in absence of injuryGO:004869640.037
phagocytosisGO:000690930.036
carbohydrate derivative metabolic processGO:1901135610.036
angiogenesisGO:00015251580.036
biosynthetic processGO:00090582940.035
establishment of localizationGO:00512342440.035
regulation of cell morphogenesis involved in differentiationGO:0010769380.035
nucleobase containing compound biosynthetic processGO:00346542050.034
ubiquitin dependent protein catabolic processGO:000651130.034
positive regulation of protein kinase b signalingGO:005189710.034
peptidyl serine phosphorylationGO:001810510.034
phosphatidylinositol 3 kinase signalingGO:001406520.034
regulation of tube sizeGO:003515020.034
gene expressionGO:00104672520.033
regulation of metabolic processGO:00192223590.033
protein localization to nucleusGO:003450430.033
camera type eye morphogenesisGO:00485931080.032
locomotionGO:00400113130.032
cartilage developmentGO:0051216960.031
negative regulation of chemotaxisGO:005092240.031
synaptic growth at neuromuscular junctionGO:005112420.031
positive regulation of cellular component movementGO:0051272110.030
transportGO:00068102200.030
cellular component assemblyGO:00226071700.030
positive regulation of cellular component biogenesisGO:004408930.030
positive regulation of epithelial cell differentiationGO:003085820.030
negative regulation of protein kinase activityGO:000646940.030
skin developmentGO:0043588540.030
blood vessel morphogenesisGO:00485142160.030
embryonic pattern specificationGO:0009880440.029
sequestering of metal ionGO:005123830.029
regulation of erk1 and erk2 cascadeGO:007037240.029
regulation of cellular metabolic processGO:00313233200.028
cell projection organizationGO:00300302840.028
cellular modified amino acid metabolic processGO:000657530.028
positive regulation of reproductive processGO:200024320.028
single organism localizationGO:19025782250.028
cellular component assembly involved in morphogenesisGO:00109271070.028
muscle fiber developmentGO:0048747520.028
cellular nitrogen compound metabolic processGO:00346412900.028
leukocyte proliferationGO:007066110.028
protein targeting to nucleusGO:004474430.028
stem cell maintenanceGO:001982740.027
membrane lipid biosynthetic processGO:004646720.027
inner ear developmentGO:00488391260.027
proteolysis involved in cellular protein catabolic processGO:005160330.027
interspecies interaction between organismsGO:004441940.027
developmental growth involved in morphogenesisGO:0060560860.027
immune system processGO:00023762410.027
nucleocytoplasmic transportGO:000691340.027
regulation of macromolecule metabolic processGO:00602553170.027
negative regulation of sequestering of calcium ionGO:005128340.027
somatic muscle developmentGO:000752540.026
regulation of cell communicationGO:00106462320.026
protein import into nucleusGO:000660630.026
tube morphogenesisGO:00352393490.026
adherens junction organizationGO:003433240.026
heart developmentGO:00075073130.026
positive regulation of catabolic processGO:000989640.026
regulation of cellular biosynthetic processGO:00313262450.026
negative regulation of nervous system developmentGO:0051961220.026
establishment of localization in cellGO:0051649770.025
regulation of reproductive processGO:200024140.025
viral processGO:001603210.025
ossificationGO:0001503230.025
negative regulation of phosphate metabolic processGO:0045936130.025
single organism behaviorGO:0044708240.025
segment specificationGO:0007379120.024
mesenchymal cell developmentGO:0014031780.024
cellular ion homeostasisGO:0006873170.024
negative regulation of mitosisGO:004583930.024
establishment of protein localization to organelleGO:007259440.024
regulation of nervous system developmentGO:0051960900.024
response to monosaccharideGO:003428430.024
negative regulation of protein phosphorylationGO:000193340.024
protein polymerizationGO:005125840.024
positive regulation of secretionGO:005104710.024
regulation of extrinsic apoptotic signaling pathwayGO:200123630.024
cell cycle g1 s phase transitionGO:004484310.024
rna metabolic processGO:00160702190.024
embryonic heart tube developmentGO:00350501330.023
production of molecular mediator of immune responseGO:000244020.023
blood circulationGO:0008015870.023
cellular component biogenesisGO:00440851780.023
cellular homeostasisGO:0019725260.023
cell morphogenesis involved in differentiationGO:00009041950.023
carboxylic acid metabolic processGO:0019752220.023
hemopoiesisGO:00300971830.023
alpha amino acid metabolic processGO:190160530.022
regulation of nucleic acid templated transcriptionGO:19035062130.022
immune system developmentGO:00025201910.022
skin morphogenesisGO:004358970.022
negative regulation of mapk cascadeGO:004340940.022
modification dependent macromolecule catabolic processGO:004363230.022
regulation of protein catabolic processGO:004217610.022
cell motilityGO:00488702440.022
cellular response to lipopolysaccharideGO:007122230.021
regenerationGO:0031099910.021
regulation of cytoplasmic transportGO:190364940.021
regulation of sequestering of calcium ionGO:005128240.021
regulation of protein import into nucleusGO:004230620.021
amine metabolic processGO:000930820.021
macromolecule modificationGO:00434121110.021
regulation of signalingGO:00230512350.021
response to external biotic stimulusGO:0043207970.021
regulation of cellular ketone metabolic processGO:001056570.021
nuclear importGO:005117030.021
skeletal system developmentGO:00015011810.020
nitrogen compound metabolic processGO:00068073190.020
cell morphogenesisGO:00009022890.020
regulation of organ growthGO:004662030.020
female sex differentiationGO:004666040.020
regulation of cell differentiationGO:00455951420.020
negative regulation of synapse assemblyGO:005196420.020
organelle localizationGO:0051640490.020
protein importGO:001703830.020
regulation of response to biotic stimulusGO:000283120.019
negative regulation of neurogenesisGO:0050768200.019
regulation of developmental processGO:00507932470.019
response to glucoseGO:000974930.019
neuron projection extensionGO:1990138450.019
regulation of protein ubiquitinationGO:003139630.019
neuron developmentGO:00486662620.019
regulation of cellular amino acid metabolic processGO:000652100.019
regulation of protein localization to nucleusGO:190018020.019
filopodium assemblyGO:004684750.019
cell part morphogenesisGO:00329902460.019
cellular amine metabolic processGO:004410620.019
protein complex localizationGO:003150310.019
cell migrationGO:00164772370.019
transcription dna templatedGO:00063511810.018
positive regulation of immune effector processGO:000269930.018
organonitrogen compound metabolic processGO:1901564740.018
symbiosis encompassing mutualism through parasitismGO:004440340.018
establishment of organelle localizationGO:0051656450.018
developmental cell growthGO:0048588520.018
regulation of protein modification by small protein conjugation or removalGO:190332030.018
positive regulation of transportGO:005105020.018
regulation of cellular response to growth factor stimulusGO:0090287350.018
positive regulation of cytosolic calcium ion concentrationGO:000720440.018
agingGO:000756820.018
regulation of mrna splicing via spliceosomeGO:004802430.017
modification dependent protein catabolic processGO:001994130.017
sequestering of calcium ionGO:005120830.017
positive regulation of cellular catabolic processGO:003133130.017
determination of dorsal ventral asymmetryGO:0048262340.017
circulatory system processGO:0003013870.017
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.017
nucleobase containing compound metabolic processGO:00061392740.017
camera type eye developmentGO:00430102220.017
growthGO:00400071740.017
regulation of axonogenesisGO:0050770320.017
heart morphogenesisGO:00030071560.017
nucleic acid transportGO:005065720.017
organic cyclic compound metabolic processGO:19013603010.017
single organism nuclear importGO:190259330.017
response to drugGO:004249330.016
multi organism processGO:00517041340.016
regulation of rna biosynthetic processGO:20011412130.016
hormone transportGO:000991420.016
regulation of cell activationGO:005086510.016
cell projection morphogenesisGO:00488582440.016
regulation of transcription dna templatedGO:00063552130.016
fin developmentGO:0033333770.016
renal system developmentGO:0072001940.016
i kappab kinase nf kappab signalingGO:000724940.016
regulation of cell shapeGO:000836010.015
regulation of oocyte developmentGO:006028130.015
regulation of intracellular protein transportGO:003315730.015
nucleobase containing compound transportGO:001593120.015
cellular localizationGO:0051641970.015
aromatic compound biosynthetic processGO:00194382170.015
positive regulation of cell adhesionGO:004578510.015
response to carbohydrateGO:000974330.015
cellular ketone metabolic processGO:0042180110.015
negative regulation of signal transduction in absence of ligandGO:190109910.015
eye morphogenesisGO:00485921440.015
cellular amino acid metabolic processGO:000652070.015
cellular response to fibroblast growth factor stimulusGO:0044344220.015
membrane invaginationGO:001032410.015
intracellular signal transductionGO:0035556850.015
behaviorGO:0007610740.015
negative regulation of cell cycle processGO:001094890.015
positive regulation of erk1 and erk2 cascadeGO:007037420.015
microtubule cytoskeleton organizationGO:0000226330.015
lymphocyte proliferationGO:004665110.015
phagocytosis engulfmentGO:000691110.015
cellular amino acid biosynthetic processGO:000865220.015
developmental growthGO:00485891660.015
multi organism cellular processGO:004476420.015
myeloid cell differentiationGO:0030099860.014
positive regulation of multi organism processGO:004390230.014
regulation of filopodium assemblyGO:005148920.014
regulation of nucleocytoplasmic transportGO:004682220.014
regulation of dendrite developmentGO:005077330.014
regulation of cytokine biosynthetic processGO:004203510.014
cell surface receptor signaling pathwayGO:00071663250.014
urogenital system developmentGO:0001655970.014
negative regulation of mrna splicing via spliceosomeGO:004802510.014
localization of cellGO:00516742440.014
synaptic transmissionGO:0007268350.014
embryonic organ developmentGO:00485683810.014
generation of neuronsGO:00486993850.014
ion homeostasisGO:0050801410.014
immunoglobulin mediated immune responseGO:001606430.014
positive regulation of stress activated mapk cascadeGO:003287430.014
regulation of macromolecule biosynthetic processGO:00105562250.013
regulation of dna replicationGO:000627530.013
response to alkaloidGO:004327920.013
negative regulation of locomotionGO:0040013180.013
cellular component disassemblyGO:002241110.013
retina layer formationGO:0010842240.013
regulation of anatomical structure morphogenesisGO:00226031300.013
cellular response to starvationGO:000926710.013
epithelial cell differentiationGO:00308551160.013
epithelial cell proliferation involved in liver morphogenesisGO:007257520.013
embryonic organ morphogenesisGO:00485622740.013
regulation of cell migrationGO:0030334400.013
positive regulation of neuron differentiationGO:0045666120.013
single organism transportGO:00447652060.013
immunoglobulin productionGO:000237710.013
cellular response to organic substanceGO:00713101050.013
peptidyl threonine phosphorylationGO:001810710.013
taurine metabolic processGO:001953010.013
larval developmentGO:000216420.013
dna templated transcription initiationGO:000635210.013
post anal tail morphogenesisGO:0036342190.013
positive regulation of secretion by cellGO:190353210.013
segmentationGO:0035282970.013
stem cell differentiationGO:00488631170.013
organic cyclic compound biosynthetic processGO:19013622230.013
inner ear receptor cell differentiationGO:0060113290.013
regulation of locomotionGO:0040012550.013
cytoskeleton organizationGO:0007010960.013
regulation of cellular component movementGO:0051270550.013
heart joggingGO:0003146400.012
posterior lateral line neuromast developmentGO:0048919200.012
regulation of nitrogen compound metabolic processGO:00511712510.012
regulation of endothelial cell differentiationGO:004560130.012
sarcomere organizationGO:0045214260.012
signal transductionGO:00071654550.012
peptidyl serine modificationGO:001820920.012
response to external stimulusGO:00096052640.012
g1 s transition of mitotic cell cycleGO:000008210.012
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.012
response to growth factorGO:0070848390.012
negative regulation of cell communicationGO:0010648960.012
negative regulation of cellular processGO:00485232830.012
positive regulation of lipid metabolic processGO:004583410.012
neural crest cell developmentGO:0014032620.012
regulation of phosphate metabolic processGO:0019220430.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
regulation of epithelial to mesenchymal transitionGO:001071730.012
negative regulation of protein serine threonine kinase activityGO:007190120.012
extracellular structure organizationGO:0043062270.012
positive regulation of striated muscle tissue developmentGO:004584410.012
negative regulation of rna splicingGO:003311910.012
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.012
single organism cell adhesionGO:0098602290.012
exocrine pancreas developmentGO:0031017280.012
positive regulation of multicellular organismal processGO:0051240520.012
regulation of cardiac muscle contractionGO:005511720.011
actin cytoskeleton organizationGO:0030036630.011
positive regulation of cytoskeleton organizationGO:005149530.011
regulation of multicellular organismal processGO:00512392770.011
positive regulation of i kappab kinase nf kappab signalingGO:004312330.011
chemical homeostasisGO:0048878490.011
primitive hemopoiesisGO:0060215270.011
cellular response to biotic stimulusGO:007121630.011
b cell activationGO:004211320.011
muscle cell migrationGO:001481240.011
protein modification processGO:00362111000.011
fin morphogenesisGO:0033334530.011
positive regulation of epithelial cell migrationGO:001063420.011
protein heterooligomerizationGO:005129110.011
pericardium developmentGO:006003910.011
phosphatidylinositol mediated signalingGO:004801520.011
positive regulation of gene expressionGO:0010628710.011
negative regulation of axon extension involved in axon guidanceGO:004884310.011
hormone secretionGO:004687920.011
negative regulation of map kinase activityGO:004340720.011
negative regulation of developmental processGO:0051093650.011
cellular response to chemical stimulusGO:00708871570.011
cellular protein catabolic processGO:004425740.011
regulation of transmembrane transporter activityGO:002289820.011
response to biotic stimulusGO:0009607970.011
regulation of calcium ion transportGO:005192420.011
signal transduction by phosphorylationGO:0023014180.011
epithelial tube formationGO:0072175190.011
organelle assemblyGO:00709251100.011
extrinsic apoptotic signaling pathwayGO:009719130.011
stem cell developmentGO:0048864820.011
hormone biosynthetic processGO:004244630.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
internal protein amino acid acetylationGO:000647520.011
negative regulation of cytokine productionGO:000181810.010
regulation of multicellular organismal developmentGO:20000262230.010
protein acylationGO:004354330.010
negative regulation of neuron projection developmentGO:001097790.010
cellular aromatic compound metabolic processGO:00067252950.010
embryonic skeletal joint developmentGO:007249830.010
regulation of neuron projection developmentGO:0010975400.010
regulation of i kappab kinase nf kappab signalingGO:004312240.010
vasculature developmentGO:00019442780.010
regulation of developmental growthGO:0048638380.010
vasculogenesisGO:0001570410.010
interaction with hostGO:005170140.010
lipid catabolic processGO:001604240.010
regulation of dna damage response signal transduction by p53 class mediatorGO:004351640.010
system processGO:00030081850.010
response to fibroblast growth factorGO:0071774220.010
calcium ion transport into cytosolGO:006040230.010
inositol lipid mediated signalingGO:004801720.010
protein acetylationGO:000647320.010
regulation of glycoprotein metabolic processGO:190301830.010
coagulationGO:0050817130.010
rna localizationGO:000640340.010
regulation of neuron differentiationGO:0045664560.010
neuron projection regenerationGO:0031102160.010
phosphate containing compound metabolic processGO:00067961080.010

fktn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.444
disease of anatomical entityDOID:700.444
muscular diseaseDOID:008000000.444
muscle tissue diseaseDOID:6600.304
myopathyDOID:42300.304
muscular dystrophyDOID:988400.027
disease of cellular proliferationDOID:1456600.025
cancerDOID:16200.022
disease of metabolismDOID:001466700.019
inherited metabolic disorderDOID:65500.019
congenital muscular dystrophyDOID:005055700.017
organ system cancerDOID:005068600.015
colorectal cancerDOID:925600.013
intestinal cancerDOID:1015500.013
gastrointestinal system cancerDOID:311900.013
large intestine cancerDOID:567200.013