Danio rerio

5 known processes

col1a2

collagen, type I, alpha 2

(Aliases: wu:fa98d05,wu:fb04c08,zehn2357,wu:fa99g10,alpha2(I),wu:fb11d06,hm:zehn2357)

col1a2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ossificationGO:0001503230.984
Zebrafish
collagen metabolic processGO:003296320.981
response to amino acidGO:004320020.979
Mouse
protein trimerizationGO:007020640.978
Mouse
multicellular organismal macromolecule metabolic processGO:004425920.971
collagen fibril organizationGO:003019910.950
Human
pectoral fin developmentGO:0033339500.936
Zebrafish
response to abiotic stimulusGO:00096281220.899
collagen biosynthetic processGO:003296420.893
extracellular matrix organizationGO:0030198270.887
Human
intramembranous ossificationGO:000195730.882
response to mechanical stimulusGO:0009612240.877
cellular response to retinoic acidGO:007130010.873
Rat
regulation of epithelial to mesenchymal transitionGO:001071730.834
cartilage morphogenesisGO:0060536130.832
Zebrafish
vasculature developmentGO:00019442780.787
Human
multicellular organismal metabolic processGO:004423620.780
extracellular structure organizationGO:0043062270.727
Human
direct ossificationGO:003607230.713
cartilage developmentGO:0051216960.705
Zebrafish
response to nutrientGO:000758430.703
notochord developmentGO:0030903540.677
Zebrafish
response to vitaminGO:003327330.663
response to woundingGO:00096111160.661
Zebrafish
response to corticosteroidGO:003196010.644
response to external stimulusGO:00096052640.623
trabecula formationGO:006034320.621
fin regenerationGO:0031101510.620
Zebrafish
cell migrationGO:00164772370.593
regulation of ossificationGO:003027850.563
Zebrafish
head morphogenesisGO:006032380.562
bone morphogenesisGO:0060349110.529
endochondral bone morphogenesisGO:006035080.508
mesenchyme developmentGO:00604851270.499
chondrocyte developmentGO:000206340.468
fin developmentGO:0033333770.463
Zebrafish
positive regulation of canonical wnt signaling pathwayGO:009026340.453
cell adhesionGO:0007155400.444
skin morphogenesisGO:004358970.437
Human
cell substrate adhesionGO:003158940.435
stem cell differentiationGO:00488631170.430
regulation of cell substrate adhesionGO:001081010.427
sensory perception of mechanical stimulusGO:0050954160.403
visual perceptionGO:0007601170.401
extracellular matrix constituent secretionGO:007027830.371
cellular response to acid chemicalGO:007122980.367
Mouse Rat
proteoglycan metabolic processGO:0006029140.350
regulation of multicellular organismal processGO:00512392770.348
Zebrafish
skin developmentGO:0043588540.343
Human
single organism metabolic processGO:00447102170.331
appendage morphogenesisGO:0035107560.316
Zebrafish
cellular response to external stimulusGO:007149620.312
embryonic organ developmentGO:00485683810.309
Zebrafish
regulation of stem cell differentiationGO:200073640.307
odontogenesisGO:004247690.303
cell motilityGO:00488702440.296
regulation of response to stimulusGO:00485832690.281
regenerationGO:0031099910.278
Zebrafish
cellular response to vitaminGO:007129510.276
digestive system developmentGO:00551232890.259
tissue regenerationGO:0042246740.258
Zebrafish
mesenchymal cell differentiationGO:0048762870.254
canonical wnt signaling pathwayGO:0060070480.252
epithelial to mesenchymal transitionGO:0001837210.250
chordate embryonic developmentGO:00430092710.242
growthGO:00400071740.237
Zebrafish
cellular component assemblyGO:00226071700.237
Mouse
bone developmentGO:0060348140.230
regulation of metabolic processGO:00192223590.228
regulation of signalingGO:00230512350.228
skeletal muscle organ developmentGO:0060538780.226
regulation of signal transductionGO:00099662250.218
response to acid chemicalGO:0001101170.210
Mouse Rat
system processGO:00030081850.203
Human
cell morphogenesisGO:00009022890.198
response to hydrogen peroxideGO:004254230.197
mesoderm developmentGO:0007498880.188
fin morphogenesisGO:0033334530.188
Zebrafish
regulation of developmental processGO:00507932470.186
regulation of mesoderm developmentGO:2000380110.185
sensory perception of soundGO:000760590.177
muscle organ developmentGO:00075171010.176
muscle attachmentGO:001620390.174
morphogenesis of an epitheliumGO:00020093330.171
positive regulation of cell motilityGO:2000147110.171
face morphogenesisGO:006032560.169
biological adhesionGO:0022610400.167
positive regulation of biological processGO:00485182530.161
cellular response to organic substanceGO:00713101050.158
Human Mouse Rat
neurological system processGO:0050877620.156
regulation of canonical wnt signaling pathwayGO:0060828340.155
cellular macromolecule metabolic processGO:00442603910.148
inner ear developmentGO:00488391260.144
growth plate cartilage developmentGO:000341720.141
response to drugGO:004249330.133
angiogenesisGO:00015251580.129
tube morphogenesisGO:00352393490.128
muscle structure developmentGO:00610611960.127
negative regulation of biological processGO:00485193040.126
endodermal cell fate determinationGO:000749320.126
appendage developmentGO:0048736800.121
Zebrafish
cellular response to fibroblast growth factor stimulusGO:0044344220.121
heart contractionGO:0060047710.120
cartilage development involved in endochondral bone morphogenesisGO:006035180.117
response to inorganic substanceGO:0010035380.117
eye morphogenesisGO:00485921440.115
response to estradiolGO:003235560.113
positive regulation of metabolic processGO:00098931080.113
hematopoietic or lymphoid organ developmentGO:00485341910.111
formation of primary germ layerGO:0001704620.111
hatchingGO:003518840.110
cellular biosynthetic processGO:00442492860.108
sensory perceptionGO:0007600390.107
skeletal system developmentGO:00015011810.106
Human Zebrafish
embryonic skeletal system developmentGO:0048706970.105
protein heterooligomerizationGO:005129110.105
Mouse
biomineral tissue developmentGO:0031214130.104
regulation of nucleic acid templated transcriptionGO:19035062130.102
rna metabolic processGO:00160702190.099
cell morphogenesis involved in differentiationGO:00009041950.098
response to cytokineGO:003409770.097
eye developmentGO:00016542770.097
cellular response to oxygen containing compoundGO:1901701200.096
Mouse Rat
regulation of cell migrationGO:0030334400.095
gene expressionGO:00104672520.095
cellular response to extracellular stimulusGO:003166820.094
regulation of wnt signaling pathwayGO:0030111530.094
digestive tract developmentGO:00485652650.094
cellular response to growth factor stimulusGO:0071363390.094
Human
response to topologically incorrect proteinGO:003596620.093
wound healingGO:0042060900.091
Zebrafish
positive regulation of multicellular organismal processGO:0051240520.091
sensory organ developmentGO:00074233930.090
osteoblast differentiationGO:000164950.088
muscle cell developmentGO:00550011150.086
positive regulation of cellular component movementGO:0051272110.084
response to other organismGO:0051707970.082
regulation of macromolecule metabolic processGO:00602553170.081
sensory perception of light stimulusGO:0050953190.078
cellular response to organic cyclic compoundGO:0071407380.077
cellular response to endogenous stimulusGO:0071495680.077
Human Mouse Rat
heart morphogenesisGO:00030071560.071
medial fin morphogenesisGO:0035141140.071
cellular nitrogen compound biosynthetic processGO:00442712180.071
regulation of cell motilityGO:2000145460.070
negative regulation of cellular processGO:00485232830.070
cellular component morphogenesisGO:00329893360.070
developmental growth involved in morphogenesisGO:0060560860.070
regulation of protein ubiquitinationGO:003139630.067
cartilage condensationGO:000150230.067
positive regulation of mesenchymal cell proliferationGO:000205310.067
endodermal cell differentiationGO:0035987190.066
positive regulation of cell migrationGO:0030335110.065
regulation of cell morphogenesisGO:0022604420.065
embryonic limb morphogenesisGO:003032620.065
regulation of biosynthetic processGO:00098892500.064
regulation of cell communicationGO:00106462320.063
response to estrogenGO:0043627270.063
spermatid differentiationGO:004851520.061
embryo development ending in birth or egg hatchingGO:00097922710.061
stem cell developmentGO:0048864820.061
macromolecule biosynthetic processGO:00090592270.060
regulation of gene expressionGO:00104682650.058
response to fibroblast growth factorGO:0071774220.058
response to oxygen levelsGO:0070482250.055
spermatid developmentGO:000728620.055
skeletal system morphogenesisGO:00487051020.054
positive regulation of epithelial cell migrationGO:001063420.053
mucopolysaccharide metabolic processGO:190351020.053
negative regulation of epithelial cell proliferationGO:005068010.050
embryonic organ morphogenesisGO:00485622740.049
cellular response to organonitrogen compoundGO:007141750.048
Mouse
response to steroid hormoneGO:0048545350.048
cellular aromatic compound metabolic processGO:00067252950.048
basement membrane assemblyGO:007083130.047
response to glucocorticoidGO:005138410.046
mesenchymal cell developmentGO:0014031780.046
agingGO:000756820.045
negative regulation of protein processingGO:0010955100.045
inner ear morphogenesisGO:0042472630.045
blood vessel morphogenesisGO:00485142160.045
regulation of multicellular organismal developmentGO:20000262230.044
locomotionGO:00400113130.044
regulation of cell morphogenesis involved in differentiationGO:0010769380.043
eye photoreceptor cell developmentGO:0042462300.043
nitrogen compound metabolic processGO:00068073190.043
regulation of cellular metabolic processGO:00313233200.043
leukocyte homeostasisGO:000177620.042
cellular response to chemical stimulusGO:00708871570.042
Human Mouse Rat
regulation of chondrocyte differentiationGO:003233010.042
blood vessel developmentGO:00015682460.042
Human
nucleobase containing compound metabolic processGO:00061392740.042
regulation of nitrogen compound metabolic processGO:00511712510.041
connective tissue developmentGO:0061448990.041
Zebrafish
cellular response to lipidGO:0071396390.041
Rat
bone mineralizationGO:003028290.039
regulation of protein modification by small protein conjugation or removalGO:190332030.039
positive regulation of cell activationGO:005086710.038
organic cyclic compound metabolic processGO:19013603010.038
regulation of cellular macromolecule biosynthetic processGO:20001122220.037
cell aggregationGO:009874330.037
regulation of endodermal cell differentiationGO:1903224150.037
cellular component movementGO:00069283350.036
cellular response to nutrientGO:003167010.036
regulation of notch signaling pathwayGO:0008593160.036
positive regulation of cell adhesionGO:004578510.036
positive regulation of macromolecule metabolic processGO:0010604930.036
regulation of endothelial cell proliferationGO:000193610.035
lipid digestionGO:004424130.034
endoderm formationGO:0001706290.033
regulation of rna metabolic processGO:00512522240.033
striated muscle cell developmentGO:00550021080.033
anatomical structure homeostasisGO:0060249360.032
macrophage chemotaxisGO:004824630.032
positive regulation of locomotionGO:0040017140.032
regulation of cytokine productionGO:000181730.031
face developmentGO:006032480.031
immune system developmentGO:00025201910.031
response to biotic stimulusGO:0009607970.030
regulation of cysteine type endopeptidase activityGO:2000116210.030
organic substance biosynthetic processGO:19015762890.030
negative regulation of metabolic processGO:0009892860.029
response to organic substanceGO:00100331530.029
Human Mouse Rat
regulation of locomotionGO:0040012550.029
body morphogenesisGO:0010171160.029
positive regulation of response to stimulusGO:0048584800.029
regulation of primary metabolic processGO:00800903110.029
response to lipidGO:0033993600.028
Rat
developmental growthGO:00485891660.028
Zebrafish
response to chemicalGO:00422213200.028
Human Mouse Rat
response to external biotic stimulusGO:0043207970.028
nucleoside monophosphate catabolic processGO:000912540.028
regulation of cellular biosynthetic processGO:00313262450.027
neuron differentiationGO:00301823530.027
response to growth factorGO:0070848390.027
Human
positive regulation of gene expressionGO:0010628710.027
positive regulation of apoptotic processGO:0043065290.027
tissue remodelingGO:004877140.027
limb bud formationGO:006017420.027
meiotic nuclear divisionGO:000712640.027
regulation of cellular component organizationGO:0051128860.026
positive regulation of immune system processGO:0002684170.026
striated muscle cell differentiationGO:00511461290.026
heart developmentGO:00075073130.026
regulation of cell activationGO:005086510.026
cell projection organizationGO:00300302840.025
glial cell migrationGO:000834730.025
transcription dna templatedGO:00063511810.025
regulation of cellular component movementGO:0051270550.024
response to carbohydrateGO:000974330.024
negative regulation of cell adhesionGO:000716260.024
striated muscle tissue developmentGO:00147061100.024
cell growthGO:0016049570.023
regionalizationGO:00030022740.023
negative regulation of multicellular organismal processGO:0051241690.023
gastrulationGO:00073692080.023
sensory organ morphogenesisGO:00905962000.023
embryonic eye morphogenesisGO:0048048300.023
eye photoreceptor cell differentiationGO:0001754450.022
positive regulation of nucleic acid templated transcriptionGO:1903508570.022
negative regulation of embryonic developmentGO:0045992110.021
positive regulation of rna biosynthetic processGO:1902680570.021
response to extracellular stimulusGO:0009991100.021
positive regulation of cell differentiationGO:0045597300.021
positive regulation of cell deathGO:0010942290.021
camera type eye developmentGO:00430102220.021
heterocycle biosynthetic processGO:00181302150.021
proteolysis involved in cellular protein catabolic processGO:005160330.021
cellular response to cytokine stimulusGO:007134570.020
dendrite guidanceGO:007098300.020
positive regulation of cellular biosynthetic processGO:0031328680.020
muscle tissue developmentGO:00605371100.020
regulation of cell projection assemblyGO:006049140.020
organic acid metabolic processGO:0006082310.020
positive regulation of stress activated mapk cascadeGO:003287430.019
response to stressGO:00069502630.019
Zebrafish
regulation of cell adhesionGO:0030155150.019
positive regulation of signalingGO:0023056560.019
endodermal digestive tract morphogenesisGO:006103120.019
long chain fatty acid transportGO:001590910.019
camera type eye morphogenesisGO:00485931080.018
cellular response to nitrogen compoundGO:190169960.018
Mouse
biosynthetic processGO:00090582940.018
regulation of nucleobase containing compound metabolic processGO:00192192500.018
regulation of cell differentiationGO:00455951420.018
somitogenesisGO:0001756870.017
er nucleus signaling pathwayGO:000698420.017
signal transductionGO:00071654550.017
Human
phagocytosisGO:000690930.017
aromatic compound biosynthetic processGO:00194382170.017
negative regulation of mesoderm developmentGO:200038150.016
positive regulation of leukocyte differentiationGO:190210710.016
nucleic acid templated transcriptionGO:00976591810.016
positive regulation of developmental processGO:0051094500.016
positive regulation of lipase activityGO:006019310.016
blood circulationGO:0008015870.016
Human
nitric oxide biosynthetic processGO:000680920.016
nucleobase containing compound biosynthetic processGO:00346542050.015
positive regulation of programmed cell deathGO:0043068290.015
single organism biosynthetic processGO:0044711710.015
smoothened signaling pathwayGO:0007224300.015
negative regulation of wound healingGO:006104510.015
rna biosynthetic processGO:00327741810.015
ear morphogenesisGO:0042471640.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.015
Human
negative regulation of cytokine productionGO:000181810.015
mitochondrion organizationGO:000700540.015
membrane invaginationGO:001032410.014
positive regulation of cellular processGO:00485222010.014
negative regulation of macromolecule metabolic processGO:0010605760.014
glycoprotein metabolic processGO:0009100230.014
cardioblast migrationGO:000326070.014
actin filament based processGO:0030029640.014
positive regulation of cytokine productionGO:000181920.014
protein localizationGO:0008104400.014
organism emergence from protective structureGO:007168440.014
cell surface receptor signaling pathwayGO:00071663250.014
Human
protein complex subunit organizationGO:0071822460.014
Human Mouse
regulation of gastrulationGO:0010470240.014
negative regulation of developmental processGO:0051093650.014
endomembrane system organizationGO:0010256130.013
regulation of cell deathGO:00109411030.013
epithelial cell morphogenesisGO:000338220.013
positive regulation of biosynthetic processGO:0009891680.013
cellular component biogenesisGO:00440851780.013
Mouse
cell projection assemblyGO:0030031640.013
cellular response to abiotic stimulusGO:007121440.013
cardiac chamber morphogenesisGO:0003206120.013
positive regulation of cellular metabolic processGO:0031325940.013
response to monosaccharideGO:003428430.013
positive regulation of signal transductionGO:0009967560.013
positive regulation of wnt signaling pathwayGO:0030177130.013
regulation of macromolecule biosynthetic processGO:00105562250.013
ameboidal type cell migrationGO:00016671430.013
cell fate specificationGO:0001708680.013
regulation of mrna splicing via spliceosomeGO:004802430.013
ear developmentGO:00435831270.013
positive regulation of immune effector processGO:000269930.012
heart processGO:0003015710.012
cellular response to xenobiotic stimulusGO:0071466350.012
alternative mrna splicing via spliceosomeGO:000038010.012
response to hormoneGO:0009725480.012
Rat
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.012
cell projection morphogenesisGO:00488582440.012
fatty acid transportGO:001590810.012
response to peptideGO:190165260.012
nitric oxide metabolic processGO:004620920.012
regulation of rna biosynthetic processGO:20011412130.011
regulation of extrinsic apoptotic signaling pathwayGO:200123630.011
positive regulation of lipid metabolic processGO:004583410.011
protein localization to nucleusGO:003450430.011
positive regulation of leukocyte migrationGO:000268720.011
response to endogenous stimulusGO:0009719830.011
Human Mouse Rat
positive regulation of endopeptidase activityGO:0010950100.011
foregut morphogenesisGO:000744040.011
negative regulation of gastrulationGO:2000542110.011
renal system vasculature developmentGO:006143720.011
small molecule metabolic processGO:0044281770.011
regulation of immune system processGO:0002682340.011
regulation of multicellular organism growthGO:004001440.011
zymogen activationGO:003163830.011
cranial suture morphogenesisGO:006036310.011
embryonic digestive tract morphogenesisGO:004855730.011
cellular nitrogen compound metabolic processGO:00346412900.011
glomerulus vasculature developmentGO:007201220.011
cellular component assembly involved in morphogenesisGO:00109271070.011
negative regulation of mesodermal cell fate specificationGO:004266230.011
regulation of mrna processingGO:005068430.010
axonogenesis involved in innervationGO:006038510.010
cellular protein catabolic processGO:004425740.010
cardiac atrium developmentGO:000323040.010
transportGO:00068102200.010
beta amyloid metabolic processGO:005043510.010
positive regulation of cell communicationGO:0010647560.010
regulation of wound healingGO:006104120.010
circulatory system processGO:0003013870.010
Human
cell proliferationGO:0008283800.010
regulation of anatomical structure morphogenesisGO:00226031300.010

col1a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.968
Human
musculoskeletal system diseaseDOID:1700.968
Human
osteochondrodysplasiaDOID:225600.968
Human
bone diseaseDOID:008000100.968
Human
bone development diseaseDOID:008000600.968
Human
connective tissue diseaseDOID:6500.968
Human
bone resorption diseaseDOID:008001100.903
Human
bone remodeling diseaseDOID:008000500.903
Human
osteoporosisDOID:1147600.726
Human
osteogenesis imperfectaDOID:1234700.410
Human
charcot marie tooth diseaseDOID:1059500.039
nervous system diseaseDOID:86300.039
neuromuscular diseaseDOID:44000.039
neuropathyDOID:87000.039
charcot marie tooth disease type 4DOID:005054100.039
cancerDOID:16200.023
organ system cancerDOID:005068600.023
gastrointestinal system cancerDOID:311900.023
disease of cellular proliferationDOID:1456600.023
reproductive organ cancerDOID:19300.010