Danio rerio

32 known processes

orai1

ORAI calcium release-activated calcium modulator 1

(Aliases: FLJ14466,zgc:109721,im:7146264,tmem142a)

orai1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.226
positive regulation of transportGO:005105020.089
cellular macromolecule metabolic processGO:00442603910.086
signal transductionGO:00071654550.080
heterocycle metabolic processGO:00464832900.078
agingGO:000756820.074
small molecule metabolic processGO:0044281770.070
negative regulation of cellular processGO:00485232830.068
multicellular organism growthGO:003526440.063
nitrogen compound metabolic processGO:00068073190.062
single organism metabolic processGO:00447102170.062
cellular component morphogenesisGO:00329893360.062
nuclear transportGO:005116940.060
cell morphogenesisGO:00009022890.057
biosynthetic processGO:00090582940.056
cellular aromatic compound metabolic processGO:00067252950.056
regulation of protein transportGO:005122330.055
single organism transportGO:00447652060.055
morphogenesis of an epitheliumGO:00020093330.054
cell projection morphogenesisGO:00488582440.054
embryonic organ developmentGO:00485683810.054
cellular nitrogen compound metabolic processGO:00346412900.052
glucose homeostasisGO:004259310.052
lipid storageGO:001991510.052
regulation of metabolic processGO:00192223590.051
regulation of establishment of protein localizationGO:007020140.051
nucleobase containing compound metabolic processGO:00061392740.051
regulation of nitrogen compound metabolic processGO:00511712510.049
cell projection organizationGO:00300302840.049
positive regulation of catabolic processGO:000989640.048
regulation of cellular metabolic processGO:00313233200.048
response to stressGO:00069502630.047
organonitrogen compound metabolic processGO:1901564740.047
oxoacid metabolic processGO:0043436310.047
positive regulation of cellular component biogenesisGO:004408930.047
regulation of primary metabolic processGO:00800903110.046
autophagyGO:000691440.046
single organism localizationGO:19025782250.045
response to chemicalGO:00422213200.045
response to drugGO:004249330.044
digestive system developmentGO:00551232890.044
organic cyclic compound metabolic processGO:19013603010.044
cognitionGO:005089010.044
generation of neuronsGO:00486993850.044
phagocytosisGO:000690930.044
negative regulation of protein phosphorylationGO:000193340.043
embryonic organ morphogenesisGO:00485622740.043
gland developmentGO:00487321430.043
digestive tract morphogenesisGO:00485462310.043
regulation of multicellular organism growthGO:004001440.043
cell migrationGO:00164772370.043
establishment of protein localization to organelleGO:007259440.042
regulation of biological qualityGO:00650082630.042
organic substance biosynthetic processGO:19015762890.042
cellular amino acid metabolic processGO:000652070.042
protein localization to nucleusGO:003450430.041
cell part morphogenesisGO:00329902460.041
regulation of protein complex assemblyGO:004325430.041
heart developmentGO:00075073130.040
regulation of response to nutrient levelsGO:003210710.040
maintenance of locationGO:005123540.040
positive regulation of protein complex assemblyGO:003133420.040
stem cell maintenanceGO:001982740.040
regulation of cellular amino acid metabolic processGO:000652100.038
sensory organ developmentGO:00074233930.038
cell substrate adhesionGO:003158940.038
regulation of macromolecule metabolic processGO:00602553170.038
regulation of response to stimulusGO:00485832690.038
response to carbohydrateGO:000974330.038
rna metabolic processGO:00160702190.038
cellular macromolecule biosynthetic processGO:00346452240.038
regulation of synaptic plasticityGO:004816710.038
positive regulation of biological processGO:00485182530.038
negative regulation of kinase activityGO:003367340.037
locomotionGO:00400113130.037
positive regulation of cellular catabolic processGO:003133130.037
negative regulation of biological processGO:00485193040.037
cellular component movementGO:00069283350.037
positive regulation of secretion by cellGO:190353210.037
protein targeting to nucleusGO:004474430.037
nucleobase containing compound biosynthetic processGO:00346542050.036
protein importGO:001703830.036
regulation of cellular biosynthetic processGO:00313262450.036
digestive tract developmentGO:00485652650.036
stem cell proliferationGO:007208940.036
central nervous system developmentGO:00074173870.036
organic acid metabolic processGO:0006082310.036
cellular amine metabolic processGO:004410620.035
heterocycle biosynthetic processGO:00181302150.035
response to hexoseGO:000974630.035
response to monosaccharideGO:003428430.035
regulation of signal transductionGO:00099662250.035
establishment of localizationGO:00512342440.035
amine metabolic processGO:000930820.035
mitochondrion organizationGO:000700540.035
regulation of intracellular protein transportGO:003315730.035
tube morphogenesisGO:00352393490.035
hormone transportGO:000991420.034
regulation of macromolecule biosynthetic processGO:00105562250.034
transportGO:00068102200.034
meiotic nuclear divisionGO:000712640.034
cellular biosynthetic processGO:00442492860.034
negative regulation of protein kinase activityGO:000646940.034
protein import into nucleusGO:000660630.033
glucose importGO:004632320.033
positive regulation of cellular processGO:00485222010.033
organelle organizationGO:00069962270.033
cellular ketone metabolic processGO:0042180110.033
cell matrix adhesionGO:000716040.033
carboxylic acid metabolic processGO:0019752220.033
response to topologically incorrect proteinGO:003596620.033
positive regulation of cell cycleGO:004578730.032
ribonucleoside monophosphate catabolic processGO:000915840.032
cellular response to external stimulusGO:007149620.032
carbohydrate homeostasisGO:003350010.032
gastrulationGO:00073692080.032
growthGO:00400071740.032
cellular component biogenesisGO:00440851780.032
positive regulation of secretionGO:005104710.032
regulation of cytokine productionGO:000181730.032
regulation of cytoplasmic transportGO:190364940.032
nucleocytoplasmic transportGO:000691340.032
regulation of cellular amine metabolic processGO:003323800.032
cell motilityGO:00488702440.031
regionalizationGO:00030022740.031
macromolecule biosynthetic processGO:00090592270.031
neuron differentiationGO:00301823530.031
axonogenesisGO:00074091520.031
regulation of localizationGO:00328791040.031
regulation of stem cell proliferationGO:007209120.031
ear developmentGO:00435831270.030
localization of cellGO:00516742440.030
phosphate containing compound metabolic processGO:00067961080.030
regulation of protein modification by small protein conjugation or removalGO:190332030.030
response to external stimulusGO:00096052640.029
inner ear developmentGO:00488391260.029
regulation of cellular ketone metabolic processGO:001056570.029
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.029
g1 s transition of mitotic cell cycleGO:000008210.029
guanosine containing compound catabolic processGO:190106920.029
regulation of nucleobase containing compound metabolic processGO:00192192500.029
purine nucleoside monophosphate catabolic processGO:000912840.028
embryo development ending in birth or egg hatchingGO:00097922710.028
regulation of cell communicationGO:00106462320.028
nuclear importGO:005117030.028
response to nutrientGO:000758430.028
regulation of biosynthetic processGO:00098892500.028
regulation of nucleocytoplasmic transportGO:004682220.028
cell cycle g1 s phase transitionGO:004484310.027
adult behaviorGO:003053420.027
peptidyl serine phosphorylationGO:001810510.027
cell morphogenesis involved in differentiationGO:00009041950.027
regulation of cell differentiationGO:00455951420.027
regulation of protein targetingGO:190353320.027
cellular response to extracellular stimulusGO:003166820.026
intracellular signal transductionGO:0035556850.026
protein metabolic processGO:00195381830.026
cellular response to nutrient levelsGO:003166920.026
vasculature developmentGO:00019442780.026
regulation of protein ubiquitinationGO:003139630.026
establishment of protein localization to plasma membraneGO:009000210.026
cellular nitrogen compound biosynthetic processGO:00442712180.026
regulation of rna metabolic processGO:00512522240.026
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.025
programmed cell deathGO:00125011190.025
neuron developmentGO:00486662620.025
gtp metabolic processGO:004603940.025
positive regulation of map kinase activityGO:004340630.025
cytokinesisGO:000091030.025
positive regulation of cell adhesionGO:004578510.025
cellular component assemblyGO:00226071700.025
locomotor rhythmGO:004547530.025
regulation of protein localization to nucleusGO:190018020.025
cellular protein catabolic processGO:004425740.025
cellular protein metabolic processGO:00442671290.025
cellular carbohydrate metabolic processGO:004426240.025
regulation of extrinsic apoptotic signaling pathwayGO:200123630.024
aromatic compound biosynthetic processGO:00194382170.024
positive regulation of cellular amine metabolic processGO:003324000.024
response to glucoseGO:000974930.024
hematopoietic or lymphoid organ developmentGO:00485341910.024
regulation of reactive oxygen species metabolic processGO:200037720.024
regulation of bindingGO:005109830.024
alpha amino acid metabolic processGO:190160530.024
system processGO:00030081850.024
somatic muscle developmentGO:000752540.024
regulation of protein import into nucleusGO:004230620.024
deathGO:00162651210.024
cellular response to starvationGO:000926710.024
gene expressionGO:00104672520.024
regulation of cell shapeGO:000836010.024
regulation of protein catabolic processGO:004217610.024
hepaticobiliary system developmentGO:0061008980.023
response to woundingGO:00096111160.023
regulation of peptidyl tyrosine phosphorylationGO:005073010.023
brain developmentGO:00074202930.023
axon developmentGO:00615641660.023
regulation of cell activationGO:005086510.023
regulation of gene expressionGO:00104682650.023
peptidyl serine modificationGO:001820920.023
negative regulation of map kinase activityGO:004340720.023
wnt signaling pathwayGO:0016055800.022
neuron projection developmentGO:00311751800.022
hormone secretionGO:004687920.022
protein dephosphorylationGO:000647030.022
immune system processGO:00023762410.022
gtp catabolic processGO:000618420.022
actin polymerization or depolymerizationGO:000815420.022
negative regulation of protein serine threonine kinase activityGO:007190120.022
atp catabolic processGO:000620040.022
germ line stem cell maintenanceGO:003071820.021
single organism nuclear importGO:190259330.021
macromolecule modificationGO:00434121110.021
cellular amide metabolic processGO:004360340.021
negative regulation of catabolic processGO:000989530.021
cellular response to chemical stimulusGO:00708871570.021
chemosensory behaviorGO:000763510.021
extrinsic apoptotic signaling pathwayGO:009719130.021
head developmentGO:00603223030.021
developmental growthGO:00485891660.021
immune system developmentGO:00025201910.021
regulation of autophagyGO:001050630.021
multi organism processGO:00517041340.021
determination of bilateral symmetryGO:00098552040.021
neuron projection morphogenesisGO:00488121610.021
regulation of programmed cell deathGO:00430671010.021
regulation of protein polymerizationGO:003227120.021
single organism organelle organizationGO:19025891990.021
fin developmentGO:0033333770.021
cellular response to lipopolysaccharideGO:007122230.021
rna biosynthetic processGO:00327741810.020
positive regulation of nitrogen compound metabolic processGO:0051173690.020
neuron neuron synaptic transmissionGO:000727010.020
heart morphogenesisGO:00030071560.020
blood vessel developmentGO:00015682460.020
response to uvGO:000941130.020
cell morphogenesis involved in neuron differentiationGO:00486671630.020
regulation of nucleoside metabolic processGO:000911820.020
modification dependent protein catabolic processGO:001994130.020
protein modification processGO:00362111000.020
adherens junction organizationGO:003433240.020
guanosine containing compound metabolic processGO:190106840.020
protein polymerizationGO:005125840.020
negative regulation of cellular catabolic processGO:003133030.019
protein stabilizationGO:005082120.019
regulation of cell substrate adhesionGO:001081010.019
nucleic acid metabolic processGO:00903042440.019
transcription dna templatedGO:00063511810.019
liver developmentGO:0001889960.019
negative regulation of nucleocytoplasmic transportGO:004682320.019
ubiquitin dependent protein catabolic processGO:000651130.019
regulation of synapse organizationGO:005080730.019
synaptic vesicle localizationGO:009747910.019
homeostatic processGO:00425921420.019
hemopoiesisGO:00300971830.019
golgi vesicle transportGO:004819330.019
peptide transportGO:001583310.019
response to organic substanceGO:00100331530.019
regulation of neural precursor cell proliferationGO:200017730.019
outflow tract morphogenesisGO:000315110.019
response to other organismGO:0051707970.019
stem cell divisionGO:001714510.019
phosphorus metabolic processGO:00067931090.019
regulation of developmental processGO:00507932470.019
segmentationGO:0035282970.019
regulation of organelle assemblyGO:190211540.019
macroautophagyGO:001623610.018
negative regulation of protein complex assemblyGO:003133310.018
regulation of cell deathGO:00109411030.018
mitochondrial transportGO:000683920.018
positive regulation of apoptotic signaling pathwayGO:200123510.018
regulation of response to extracellular stimulusGO:003210410.018
neuroblast proliferationGO:000740520.018
regulation of nucleotide catabolic processGO:003081120.018
regulation of nucleic acid templated transcriptionGO:19035062130.018
organic cyclic compound biosynthetic processGO:19013622230.018
synaptic growth at neuromuscular junctionGO:005112420.018
tissue remodelingGO:004877140.018
apoptotic processGO:00069151160.018
regulation of jak stat cascadeGO:004642530.018
regulation of erk1 and erk2 cascadeGO:007037240.018
phagocytosis engulfmentGO:000691110.018
negative regulation of protein transportGO:005122430.018
chordate embryonic developmentGO:00430092710.018
regenerationGO:0031099910.018
regulation of reproductive processGO:200024140.018
protein secretionGO:000930610.018
cell projection assemblyGO:0030031640.018
cellular component disassemblyGO:002241110.018
positive regulation of macromolecule metabolic processGO:0010604930.018
heart contractionGO:0060047710.018
regulation of purine nucleotide catabolic processGO:003312120.017
regulation of transcription dna templatedGO:00063552130.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
neurotransmitter transportGO:000683620.017
regulation of glucose transportGO:001082710.017
membrane fusionGO:006102520.017
regulation of inflammatory responseGO:005072720.017
regulation of wound healingGO:006104120.017
regulation of dna replicationGO:000627530.017
centrosome organizationGO:005129710.017
negative regulation of metabolic processGO:0009892860.017
positive regulation of cell activationGO:005086710.017
regulation of epithelial cell proliferationGO:005067830.017
proteolysis involved in cellular protein catabolic processGO:005160330.017
neurotransmitter secretionGO:000726920.017
regulation of apoptotic processGO:0042981980.017
regulation of cell developmentGO:00602841000.017
organelle assemblyGO:00709251100.017
proteasomal protein catabolic processGO:001049820.017
cellular localizationGO:0051641970.017
cellular protein modification processGO:00064641000.017
response to hormoneGO:0009725480.017
regulation of multicellular organismal developmentGO:20000262230.017
compound eye developmentGO:004874920.017
exocytosisGO:000688710.017
modification dependent macromolecule catabolic processGO:004363230.017
positive regulation of nucleotide catabolic processGO:003081310.017
positive regulation of cytoskeleton organizationGO:005149530.017
energy reserve metabolic processGO:000611220.017
cell deathGO:00082191210.016
regulation of cell matrix adhesionGO:000195210.016
positive regulation of nucleoside metabolic processGO:004597910.016
spermatid developmentGO:000728620.016
regulation of cellular component organizationGO:0051128860.016
wound healingGO:0042060900.016
negative regulation of cell communicationGO:0010648960.016
leukocyte proliferationGO:007066110.016
sensory organ morphogenesisGO:00905962000.016
synaptic vesicle transportGO:004848910.016
regulation of skeletal muscle tissue developmentGO:004864140.016
female sex differentiationGO:004666040.016
negative regulation of mapk cascadeGO:004340940.016
cellular response to radiationGO:007147840.016
membrane invaginationGO:001032410.016
positive regulation of cellular metabolic processGO:0031325940.016
meiotic cell cycle processGO:190304630.016
response to biotic stimulusGO:0009607970.016
response to external biotic stimulusGO:0043207970.016
regulation of meiotic cell cycleGO:005144510.016
regulation of blood pressureGO:000821710.016
negative regulation of cytoplasmic transportGO:190365020.016
single organism membrane fusionGO:004480120.016
striated muscle cell developmentGO:00550021080.016
positive regulation of canonical wnt signaling pathwayGO:009026340.016
regulation of synapse assemblyGO:005196330.016
cellular component assembly involved in morphogenesisGO:00109271070.016
negative regulation of response to stimulusGO:00485851040.016
eye developmentGO:00016542770.015
regulation of neuronal synaptic plasticityGO:004816810.015
cilium morphogenesisGO:0060271850.015
positive regulation of immune effector processGO:000269930.015
carbohydrate derivative metabolic processGO:1901135610.015
negative regulation of nitrogen compound metabolic processGO:0051172590.015
regulation of stem cell differentiationGO:200073640.015
cell surface receptor signaling pathwayGO:00071663250.015
regulation of glucose importGO:004632410.015
protein localization to plasma membraneGO:007265910.015
olfactory bulb developmentGO:002177240.015
cellular modified amino acid metabolic processGO:000657530.015
erk1 and erk2 cascadeGO:007037140.015
positive regulation of wound healingGO:009030310.015
meiotic chromosome segregationGO:004513230.015
regulation of dendrite developmentGO:005077330.015
response to corticosteroidGO:003196010.015
protein acylationGO:004354330.015
negative regulation of macromolecule metabolic processGO:0010605760.015
positive regulation of metabolic processGO:00098931080.015
entrainment of circadian clockGO:000964920.015
nucleoside monophosphate catabolic processGO:000912540.015
post embryonic organ developmentGO:004856940.015
response to unfolded proteinGO:000698620.015
pigmentationGO:0043473850.015
lateral inhibitionGO:004633110.015
cell agingGO:000756920.015
long chain fatty acid metabolic processGO:000167610.015
secondary metabolic processGO:001974830.015
internal peptidyl lysine acetylationGO:001839320.015
regulation of signalingGO:00230512350.015
positive regulation of cytokine productionGO:000181920.015
regulation of protein bindingGO:004339330.015
regulation of muscle contractionGO:000693730.015
cellular respirationGO:004533330.015
lipid metabolic processGO:0006629520.015
regulation of dendrite morphogenesisGO:004881430.015
negative regulation of intracellular protein transportGO:009031730.015
regulation of circadian rhythmGO:004275240.015
rna localizationGO:000640340.015
regulation of cellular macromolecule biosynthetic processGO:20001122220.015
negative regulation of protein localization to nucleusGO:190018120.014
nuclear exportGO:005116810.014
regulation of metal ion transportGO:001095940.014
post golgi vesicle mediated transportGO:000689210.014
epithelial tube morphogenesisGO:00605621480.014
multicellular organismal response to stressGO:003355520.014
heart processGO:0003015710.014
negative regulation of multicellular organismal processGO:0051241690.014
specification of symmetryGO:00097992040.014
dorsal ventral pattern formationGO:00099531250.014
cilium assemblyGO:0042384580.014
cell proliferationGO:0008283800.014
regulation of mrna processingGO:005068430.014
regulation of translational initiationGO:000644610.014
protein acetylationGO:000647320.014
negative regulation of dna metabolic processGO:005105340.014
olfactory lobe developmentGO:002198840.014
negative regulation of cytokine productionGO:000181810.014
response to abiotic stimulusGO:00096281220.014
internal protein amino acid acetylationGO:000647520.014
circulatory system processGO:0003013870.014
cellular response to organic substanceGO:00713101050.014
negative regulation of intracellular transportGO:003238730.014
negative regulation of immune responseGO:005077720.014
development of primary female sexual characteristicsGO:004654540.014
lymphocyte proliferationGO:004665110.014
antimicrobial humoral responseGO:001973020.014
lamellipodium organizationGO:009758110.014
single organism biosynthetic processGO:0044711710.014
stem cell developmentGO:0048864820.014
regulation of receptor mediated endocytosisGO:004825940.014
translational initiationGO:000641330.014
negative regulation of protein import into nucleusGO:004230820.014
transcription from rna polymerase ii promoterGO:0006366800.014
anterior posterior pattern specificationGO:00099521520.014
positive regulation of protein polymerizationGO:003227320.014
canonical wnt signaling pathwayGO:0060070480.014
muscle structure developmentGO:00610611960.013
regulation of anatomical structure morphogenesisGO:00226031300.013
regulation of cellular carbohydrate metabolic processGO:001067540.013
forebrain cell migrationGO:002188510.013
negative regulation of signal transductionGO:0009968940.013
macromolecule localizationGO:0033036540.013
positive regulation of stem cell proliferationGO:200064810.013
spindle assemblyGO:005122520.013
regulation of multicellular organismal processGO:00512392770.013
inorganic ion transmembrane transportGO:0098660570.013
regulation of locomotionGO:0040012550.013
regulation of carbohydrate metabolic processGO:000610940.013
dicarboxylic acid metabolic processGO:004364810.013
response to superoxideGO:000030320.013
nucleic acid templated transcriptionGO:00976591810.013
circadian sleep wake cycle sleepGO:005080210.013
organophosphate metabolic processGO:0019637370.013
endosomal transportGO:001619720.013
convergent extensionGO:00600261180.013
positive regulation of blood circulationGO:190352420.013
negative regulation of synapse assemblyGO:005196420.013
activation of mapk activityGO:000018730.013
response to ketoneGO:190165410.013
actin filament polymerizationGO:003004120.013
positive regulation of purine nucleotide catabolic processGO:003312310.013
regulation of tube sizeGO:003515020.013
embryonic limb morphogenesisGO:003032620.013
positive regulation of dna metabolic processGO:005105410.013
oxidation reduction processGO:0055114410.013
positive regulation of nucleobase containing compound metabolic processGO:0045935690.013
mononuclear cell proliferationGO:003294310.013
regulation of cell projection assemblyGO:006049140.013
response to hydrogen peroxideGO:004254230.013
purine ribonucleoside monophosphate catabolic processGO:000916940.013
er nucleus signaling pathwayGO:000698420.013
sleepGO:003043110.013
neurological system processGO:0050877620.013
pectoral fin developmentGO:0033339500.013
establishment of synaptic vesicle localizationGO:009748010.013
muscle cell migrationGO:001481240.013
reactive oxygen species biosynthetic processGO:190340910.013
actin filament based processGO:0030029640.013
negative regulation of defense responseGO:003134820.013
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.013
cell cell signalingGO:0007267520.013
response to inorganic substanceGO:0010035380.013
camera type eye developmentGO:00430102220.013
negative regulation of stem cell differentiationGO:200073720.013
organelle fusionGO:004828430.013
regulation of cellular component movementGO:0051270550.013
cell substrate junction assemblyGO:000704420.013
startle responseGO:000196440.013
cellular response to hormone stimulusGO:0032870390.013
blood circulationGO:0008015870.013
skin developmentGO:0043588540.013
positive regulation of i kappab kinase nf kappab signalingGO:004312330.013
regulation of response to biotic stimulusGO:000283120.013
regulation of canonical wnt signaling pathwayGO:0060828340.013
somite developmentGO:0061053960.012
negative regulation of signalingGO:0023057960.012
purine containing compound metabolic processGO:0072521290.012
positive regulation of cellular biosynthetic processGO:0031328680.012

orai1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035
disease of metabolismDOID:001466700.023
cancerDOID:16200.023
disease of cellular proliferationDOID:1456600.023
organ system cancerDOID:005068600.022
musculoskeletal system diseaseDOID:1700.018
inherited metabolic disorderDOID:65500.016
nervous system diseaseDOID:86300.014