Danio rerio

0 known processes

kpna2

karyopherin alpha 2 (RAG cohort 1, importin alpha 1)

(Aliases: MGC113902,zgc:113902,hm:zeh0389r,hm:zeh0389,zgc:86945)

kpna2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
establishment of localizationGO:00512342440.446
Human Mouse Worm
regulation of nucleocytoplasmic transportGO:004682220.400
cytoskeleton organizationGO:0007010960.391
spindle assembly involved in mitosisGO:009030710.384
single organism organelle organizationGO:19025891990.379
regulation of chromosome segregationGO:005198310.375
spindle assemblyGO:005122520.293
hematopoietic or lymphoid organ developmentGO:00485341910.282
regulation of establishment of protein localizationGO:007020140.280
regulation of protein modification by small protein conjugation or removalGO:190332030.274
nuclear transportGO:005116940.269
Human Mouse Worm
cellular component assemblyGO:00226071700.260
transportGO:00068102200.259
Human Mouse Worm
protein localization to nucleusGO:003450430.258
Human Mouse Worm
modification dependent protein catabolic processGO:001994130.255
regulation of protein targetingGO:190353320.247
cytoskeleton dependent cytokinesisGO:006164030.246
regulation of protein import into nucleusGO:004230620.240
regulation of cytoplasmic transportGO:190364940.239
mitotic cell cycle processGO:1903047480.237
protein complex disassemblyGO:004324110.214
centrosome duplicationGO:005129810.211
protein targeting to nucleusGO:004474430.210
Human Mouse Worm
maintenance of locationGO:005123540.207
cytokinesisGO:000091030.204
single organism transportGO:00447652060.204
Human Mouse Worm
regulation of meiotic cell cycleGO:005144510.203
regulation of protein localization to nucleusGO:190018020.202
embryo development ending in birth or egg hatchingGO:00097922710.200
Worm
regulation of mitotic cell cycleGO:0007346250.164
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.155
nuclear importGO:005117030.154
Human Mouse Worm
negative regulation of protein localization to nucleusGO:190018120.154
mitotic cytokinesisGO:000028130.152
cellular component disassemblyGO:002241110.152
protein depolymerizationGO:005126110.148
meiotic cell cycle processGO:190304630.147
negative regulation of cellular processGO:00485232830.142
positive regulation of transportGO:005105020.140
protein import into nucleusGO:000660630.138
Human Mouse Worm
regulation of multicellular organismal processGO:00512392770.136
multicellular organism growthGO:003526440.135
ubiquitin dependent protein catabolic processGO:000651130.135
single organism nuclear importGO:190259330.132
Human Mouse Worm
meiosis iGO:000712710.131
proteasomal protein catabolic processGO:001049820.130
apoptotic processGO:00069151160.130
proteolysis involved in cellular protein catabolic processGO:005160330.128
negative regulation of protein transportGO:005122430.123
regulation of protein transportGO:005122330.121
establishment of protein localization to organelleGO:007259440.119
Human Mouse Worm
protein importGO:001703830.119
Human Mouse Worm
macromolecular complex subunit organizationGO:0043933740.114
negative regulation of cellular catabolic processGO:003133030.113
regulation of protein catabolic processGO:004217610.112
histone phosphorylationGO:001657220.112
regulation of biological qualityGO:00650082630.112
negative regulation of catabolic processGO:000989530.111
microtubule organizing center organizationGO:003102310.110
regulation of proteolysisGO:0030162240.110
positive regulation of cell cycleGO:004578730.109
cell cycleGO:0007049930.107
cytokinetic processGO:003250620.106
mitotic cell cycleGO:0000278640.104
cleavage furrow formationGO:003608920.103
macromolecular complex disassemblyGO:003298410.097
negative regulation of cell cycle processGO:001094890.097
larval developmentGO:000216420.097
regulation of protein depolymerizationGO:190187910.095
negative regulation of nuclear divisionGO:005178430.095
microtubule cytoskeleton organization involved in mitosisGO:190285010.094
oocyte maturationGO:000155640.093
response to stressGO:00069502630.092
mitotic nuclear divisionGO:0007067180.091
organelle organizationGO:00069962270.089
cellular component biogenesisGO:00440851780.088
negative regulation of mitosisGO:004583930.088
negative regulation of cytoplasmic transportGO:190365020.083
regulation of localizationGO:00328791040.082
negative regulation of chromosome organizationGO:200125110.082
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.080
chromosome organization involved in meiosisGO:007019210.076
immune system developmentGO:00025201910.075
centrosome cycleGO:000709810.075
deoxyribonucleotide biosynthetic processGO:000926310.072
negative regulation of protein import into nucleusGO:004230820.071
microtubule based processGO:0007017600.071
immune system processGO:00023762410.070
microtubule polymerization or depolymerizationGO:003110930.070
astral microtubule organizationGO:003095310.070
female meiotic divisionGO:000714320.069
cell deathGO:00082191210.066
gene expressionGO:00104672520.064
meiosis iiGO:000713510.063
positive regulation of catabolic processGO:000989640.062
protein complex subunit organizationGO:0071822460.062
negative regulation of protein maturationGO:1903318100.061
programmed cell deathGO:00125011190.061
protein secretionGO:000930610.060
nucleobase containing compound metabolic processGO:00061392740.059
cellular protein modification processGO:00064641000.059
regulation of multicellular organism growthGO:004001440.059
negative regulation of intracellular transportGO:003238730.058
sister chromatid segregationGO:000081960.058
deathGO:00162651210.058
regulation of microtubule depolymerizationGO:003111410.058
negative regulation of biological processGO:00485193040.058
nucleocytoplasmic transportGO:000691340.057
Human Mouse Worm
microtubule cytoskeleton organizationGO:0000226330.056
negative regulation of nucleocytoplasmic transportGO:004682320.055
positive regulation of biological processGO:00485182530.055
biosynthetic processGO:00090582940.055
macromolecule modificationGO:00434121110.054
regulation of intracellular protein transportGO:003315730.054
cellular biosynthetic processGO:00442492860.052
regulation of mitotic cell cycle phase transitionGO:190199080.052
microtubule depolymerizationGO:000701910.052
mitotic cell cycle checkpointGO:000709350.051
cellular macromolecule metabolic processGO:00442603910.051
negative regulation of intracellular protein transportGO:009031730.050
regulation of protein processingGO:0070613100.050
regulation of developmental processGO:00507932470.050
regulation of apoptotic processGO:0042981980.049
regulation of synapse organizationGO:005080730.049
cell proliferationGO:0008283800.049
regulation of cell cycleGO:0051726520.048
lateral inhibitionGO:004633110.048
cellular protein metabolic processGO:00442671290.048
hemopoiesisGO:00300971830.047
cell cycle processGO:0022402530.047
establishment of localization in cellGO:0051649770.047
Human Mouse Worm
cellular lipid catabolic processGO:004424230.047
cellular protein catabolic processGO:004425740.046
protein metabolic processGO:00195381830.046
protein modification processGO:00362111000.046
meiotic nuclear divisionGO:000712640.045
organelle assemblyGO:00709251100.044
positive regulation of cellular catabolic processGO:003133130.044
angiogenesisGO:00015251580.043
regulation of multicellular organismal developmentGO:20000262230.043
protein homooligomerizationGO:005126030.043
peptidyl serine modificationGO:001820920.042
positive regulation of chromosome segregationGO:005198410.042
regulation of macromolecule metabolic processGO:00602553170.042
negative regulation of mitotic cell cycle phase transitionGO:190199150.041
single organism localizationGO:19025782250.041
Human Mouse Worm
proteolysisGO:0006508380.041
fertilizationGO:000956630.040
negative regulation of kinase activityGO:003367340.040
regulation of primary metabolic processGO:00800903110.040
single organism intracellular transportGO:1902582250.040
Human Mouse Worm
response to drugGO:004249330.039
centrosome organizationGO:005129710.039
negative regulation of protein phosphorylationGO:000193340.038
negative regulation of protein kinase activityGO:000646940.038
regulation of cellular component organizationGO:0051128860.038
modification dependent macromolecule catabolic processGO:004363230.038
pyrimidine containing compound metabolic processGO:007252730.038
negative regulation of proteolysisGO:0045861100.037
establishment of organelle localizationGO:0051656450.037
organelle localizationGO:0051640490.037
cellular component movementGO:00069283350.037
protein polymerizationGO:005125840.037
intracellular signal transductionGO:0035556850.036
regulation of protein maturationGO:1903317100.036
phagocytosisGO:000690930.036
negative regulation of mitotic cell cycleGO:0045930110.036
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.036
cell surface receptor signaling pathwayGO:00071663250.035
cell migrationGO:00164772370.035
negative regulation of gene expressionGO:0010629650.035
regulation of cellular metabolic processGO:00313233200.035
positive regulation of macromolecule metabolic processGO:0010604930.034
cell cycle g2 m phase transitionGO:004483940.034
vasculature developmentGO:00019442780.034
single fertilizationGO:000733830.034
regulation of programmed cell deathGO:00430671010.034
negative regulation of protein processingGO:0010955100.033
positive regulation of chromosome organizationGO:200125210.033
regulation of protein complex disassemblyGO:004324410.032
positive regulation of cellular processGO:00485222010.032
meiotic chromosome segregationGO:004513230.032
neuron projection developmentGO:00311751800.032
mitotic metaphase plate congressionGO:000708010.032
phosphate containing compound metabolic processGO:00067961080.031
regulation of dendrite developmentGO:005077330.031
positive regulation of cellular metabolic processGO:0031325940.031
single organism metabolic processGO:00447102170.031
developmental growthGO:00485891660.030
female meiosis iiGO:000714710.030
regulation of transportGO:0051049450.030
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.030
regulation of cell proliferationGO:0042127370.030
positive regulation of chromatin modificationGO:190331010.030
response to antibioticGO:004667710.030
blood vessel developmentGO:00015682460.030
regulation of cell differentiationGO:00455951420.029
amine metabolic processGO:000930820.029
cellular amino acid metabolic processGO:000652070.029
protein phosphorylationGO:0006468470.029
mitotic cell cycle embryonicGO:004544820.028
negative regulation of apoptotic processGO:0043066550.028
nucleus localizationGO:005164780.027
peptidyl serine phosphorylationGO:001810510.027
signal transductionGO:00071654550.027
dna catabolic processGO:000630810.026
digestive tract developmentGO:00485652650.026
monovalent inorganic cation transportGO:0015672420.026
growthGO:00400071740.026
regulation of cellular amine metabolic processGO:003323800.026
cellular response to external stimulusGO:007149620.025
response to woundingGO:00096111160.025
protein catabolic processGO:003016370.025
cellular nitrogen compound metabolic processGO:00346412900.025
meiotic spindle organizationGO:000021210.024
neuron developmentGO:00486662620.024
regulation of microtubule polymerization or depolymerizationGO:003111030.024
cellular amine metabolic processGO:004410620.023
regulation of mitosisGO:000708890.023
cell cycle g1 s phase transitionGO:004484310.023
negative regulation of cellular component organizationGO:0051129160.023
nuclear migrationGO:000709730.023
negative regulation of macromolecule metabolic processGO:0010605760.023
negative regulation of cell divisionGO:005178240.023
regulation of molecular functionGO:0065009700.023
reproductionGO:0000003400.023
regulation of microtubule cytoskeleton organizationGO:007050730.023
positive regulation of cell divisionGO:005178120.022
intracellular transportGO:0046907320.022
Human Mouse Worm
regulation of cellular protein catabolic processGO:190336210.022
regulation of synaptic plasticityGO:004816710.022
g1 s transition of mitotic cell cycleGO:000008210.022
neuroblast proliferationGO:000740520.022
cellular localizationGO:0051641970.021
Human Mouse Worm
negative regulation of meiotic cell cycleGO:005144710.021
cellular catabolic processGO:0044248270.021
behaviorGO:0007610740.021
embryonic digestive tract morphogenesisGO:004855730.021
macromolecular complex assemblyGO:0065003350.021
regulation of establishment of planar polarityGO:009017540.021
phosphorus metabolic processGO:00067931090.020
single organism reproductive processGO:0044702400.020
regulation of heart growthGO:006042020.020
g2 m transition of mitotic cell cycleGO:000008640.020
microtubule based movementGO:0007018330.020
nuclear divisionGO:0000280230.020
regulation of protein ubiquitinationGO:003139630.020
carboxylic acid metabolic processGO:0019752220.019
catabolic processGO:0009056320.019
mitotic g2 m transition checkpointGO:004481830.019
peptidyl threonine phosphorylationGO:001810710.019
cell proliferation in forebrainGO:002184630.019
cellular response to retinoic acidGO:007130010.019
double strand break repair via homologous recombinationGO:000072410.019
vesicle mediated transportGO:0016192220.019
organic substance biosynthetic processGO:19015762890.019
pronuclear migrationGO:003504610.019
central nervous system developmentGO:00074173870.018
response to biotic stimulusGO:0009607970.018
negative regulation of cellular metabolic processGO:0031324770.018
organic substance transportGO:0071702580.018
Human Mouse Worm
cellular response to dna damage stimulusGO:0006974240.018
negative regulation of organelle organizationGO:001063940.018
deoxyribonucleotide metabolic processGO:000926210.018
blood vessel morphogenesisGO:00485142160.018
adult behaviorGO:003053420.018
positive regulation of histone modificationGO:003105810.018
positive regulation of cellular amine metabolic processGO:003324000.018
protein processingGO:0016485120.018
cellular response to stressGO:0033554620.018
regulation of gene expressionGO:00104682650.017
cellular response to extracellular stimulusGO:003166820.017
dna biosynthetic processGO:007189730.017
generation of neuronsGO:00486993850.017
cation transportGO:0006812810.017
organic acid metabolic processGO:0006082310.017
locomotionGO:00400113130.017
ribonucleoside monophosphate catabolic processGO:000915840.017
mitotic dna integrity checkpointGO:004477440.017
recombinational repairGO:000072510.017
heterocycle metabolic processGO:00464832900.017
regulation of cytoskeleton organizationGO:0051493110.017
urogenital system developmentGO:0001655970.016
wnt signaling pathway planar cell polarity pathwayGO:006007140.016
positive regulation of dna metabolic processGO:005105410.016
nucleic acid metabolic processGO:00903042440.016
regulation of response to stimulusGO:00485832690.016
positive regulation of rna metabolic processGO:0051254590.016
localization of cellGO:00516742440.016
cell cycle arrestGO:000705010.016
homeostatic processGO:00425921420.016
positive regulation of transcription dna templatedGO:0045893570.016
regulation of transferase activityGO:0051338160.016
regulation of blood pressureGO:000821710.016
i kappab kinase nf kappab signalingGO:000724940.016
regulation of endopeptidase activityGO:0052548230.016
regulation of protein metabolic processGO:0051246560.015
wound healingGO:0042060900.015
cellular aromatic compound metabolic processGO:00067252950.015
protein maturationGO:0051604120.015
cellular ketone metabolic processGO:0042180110.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
epithelial tube morphogenesisGO:00605621480.015
digestive system developmentGO:00551232890.015
rna metabolic processGO:00160702190.015
negative regulation of cell deathGO:0060548600.015
protein dephosphorylationGO:000647030.015
positive regulation of cytoskeleton organizationGO:005149530.015
positive regulation of metabolic processGO:00098931080.015
double strand break repairGO:000630230.015
response to external stimulusGO:00096052640.014
regulation of systemic arterial blood pressureGO:000307310.014
negative regulation of metabolic processGO:0009892860.014
regulation of cellular protein metabolic processGO:0032268520.014
cellular protein complex disassemblyGO:004362410.014
single organism membrane fusionGO:004480120.014
organelle fusionGO:004828430.014
regulation of cell migrationGO:0030334400.014
response to organic substanceGO:00100331530.014
pyrimidine nucleotide metabolic processGO:000622010.014
stem cell maintenanceGO:001982740.014
phosphorylationGO:0016310690.014
protein modification by small protein conjugation or removalGO:0070647140.014
cytoplasmic transportGO:0016482110.014
Human Mouse Worm
regulation of cellular ketone metabolic processGO:001056570.014
cell cell signalingGO:0007267520.014
regulation of cell projection organizationGO:0031344440.013
nitrogen compound metabolic processGO:00068073190.013
organelle fissionGO:0048285230.013
transcription dna templatedGO:00063511810.013
positive regulation of nitrogen compound metabolic processGO:0051173690.013
regulation of dna replicationGO:000627530.013
negative regulation of cellular protein metabolic processGO:0032269160.013
cardiac atrium developmentGO:000323040.013
gene silencing by rnaGO:003104740.013
reciprocal dna recombinationGO:003582510.013
protein oligomerizationGO:005125970.013
regulation of cell deathGO:00109411030.013
cellular nitrogen compound biosynthetic processGO:00442712180.012
regulation of neural precursor cell proliferationGO:200017730.012
cell cycle phase transitionGO:004477090.012
gland developmentGO:00487321430.012
ameboidal type cell migrationGO:00016671430.012
regulation of nitrogen compound metabolic processGO:00511712510.012
cellular macromolecular complex assemblyGO:0034622240.012
cellular protein localizationGO:0034613200.012
Human Mouse Worm
sensory organ developmentGO:00074233930.012
lipid catabolic processGO:001604240.012
cell agingGO:000756920.012
g2 dna damage checkpointGO:003157230.012
aromatic compound biosynthetic processGO:00194382170.012
atp catabolic processGO:000620040.012
regulation of growthGO:0040008420.012
regulation of protein modification processGO:0031399290.012
protein complex biogenesisGO:0070271300.012
action potentialGO:0001508190.011
regulation of protein bindingGO:004339330.011
regulation of microtubule based processGO:003288660.011
male meiosisGO:000714020.011
posttranscriptional gene silencing by rnaGO:003519430.011
cell projection organizationGO:00300302840.011
mitotic spindle organizationGO:000705250.011
germ line stem cell maintenanceGO:003071820.011
response to hypoxiaGO:0001666250.011
golgi organizationGO:000703010.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280100.011
response to chemicalGO:00422213200.011
cellular component assembly involved in morphogenesisGO:00109271070.011
extrinsic apoptotic signaling pathwayGO:009719130.011
response to hormoneGO:0009725480.011
chromosome segregationGO:0007059120.011
spermatid differentiationGO:004851520.011
regulation of peptidyl tyrosine phosphorylationGO:005073010.011
microtubule polymerizationGO:004678520.011
negative regulation of programmed cell deathGO:0043069580.011
oxoacid metabolic processGO:0043436310.010
nucleoside monophosphate catabolic processGO:000912540.010
cell substrate adhesionGO:003158940.010
negative regulation of catalytic activityGO:0043086210.010
regulation of metabolic processGO:00192223590.010
heart developmentGO:00075073130.010
spindle organizationGO:000705150.010
multi organism processGO:00517041340.010
regulation of protein complex assemblyGO:004325430.010
regulation of stem cell proliferationGO:007209120.010
macromolecule catabolic processGO:0009057150.010

kpna2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
gastrointestinal system cancerDOID:311900.015
organ system cancerDOID:005068600.015
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.015