Danio rerio

0 known processes

optc

opticin

(Aliases: zgc:101047,wu:fb81a05)

optc biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of nucleotide catabolic processGO:003081120.489
organophosphate metabolic processGO:0019637370.430
regulation of metabolic processGO:00192223590.361
regulation of primary metabolic processGO:00800903110.337
positive regulation of biological processGO:00485182530.318
organic cyclic compound metabolic processGO:19013603010.276
chordate embryonic developmentGO:00430092710.268
nitrogen compound metabolic processGO:00068073190.266
nucleoside phosphate metabolic processGO:0006753280.249
nucleobase containing small molecule metabolic processGO:0055086320.243
nucleobase containing compound metabolic processGO:00061392740.238
cellular biosynthetic processGO:00442492860.235
small molecule metabolic processGO:0044281770.231
alpha amino acid metabolic processGO:190160530.227
nucleotide metabolic processGO:0009117280.217
embryonic organ developmentGO:00485683810.212
agingGO:000756820.210
maintenance of locationGO:005123540.209
muscle structure developmentGO:00610611960.202
neuron differentiationGO:00301823530.181
positive regulation of cellular processGO:00485222010.177
cellular amino acid biosynthetic processGO:000865220.176
embryo development ending in birth or egg hatchingGO:00097922710.167
cellular aromatic compound metabolic processGO:00067252950.164
regulation of nucleoside metabolic processGO:000911820.164
negative regulation of nuclear divisionGO:005178430.160
regulation of gtp catabolic processGO:003312420.155
gtp metabolic processGO:004603940.153
regulation of nucleotide metabolic processGO:0006140170.144
regulation of molecular functionGO:0065009700.141
cellular nitrogen compound metabolic processGO:00346412900.138
organic substance biosynthetic processGO:19015762890.131
organonitrogen compound metabolic processGO:1901564740.128
regulation of mrna splicing via spliceosomeGO:004802430.126
cellular macromolecule biosynthetic processGO:00346452240.123
notochord developmentGO:0030903540.121
regulation of response to stimulusGO:00485832690.117
alternative mrna splicing via spliceosomeGO:000038010.117
response to organic substanceGO:00100331530.114
regulation of macromolecule metabolic processGO:00602553170.114
regulation of signalingGO:00230512350.112
generation of neuronsGO:00486993850.111
larval developmentGO:000216420.107
regulation of purine nucleotide catabolic processGO:003312120.107
rna biosynthetic processGO:00327741810.107
phosphorus metabolic processGO:00067931090.105
anterior posterior pattern specificationGO:00099521520.104
carboxylic acid catabolic processGO:004639530.097
organic acid metabolic processGO:0006082310.088
regionalizationGO:00030022740.088
cellular macromolecule metabolic processGO:00442603910.088
regulation of multicellular organismal developmentGO:20000262230.087
Mouse
somitogenesisGO:0001756870.085
regulation of nitrogen compound metabolic processGO:00511712510.083
hepatocyte proliferationGO:007257420.080
regulation of biological qualityGO:00650082630.080
positive regulation of transportGO:005105020.080
regulation of nucleobase containing compound metabolic processGO:00192192500.078
purine containing compound metabolic processGO:0072521290.078
vasculature developmentGO:00019442780.076
Mouse
oxidation reduction processGO:0055114410.076
regulation of alternative mrna splicing via spliceosomeGO:000038110.075
heterocycle metabolic processGO:00464832900.075
mediolateral intercalationGO:006003130.074
purine ribonucleotide metabolic processGO:0009150270.074
regulation of catalytic activityGO:0050790550.073
apoptotic process involved in morphogenesisGO:006056120.071
epithelial cell differentiationGO:00308551160.069
embryonic cranial skeleton morphogenesisGO:0048701900.069
optic placode formationGO:000174340.068
macromolecule methylationGO:0043414190.068
positive regulation of catabolic processGO:000989640.068
lipid storageGO:001991510.067
neuron developmentGO:00486662620.065
regulation of multicellular organismal processGO:00512392770.062
Mouse
multicellular organism growthGO:003526440.062
regulation of signal transductionGO:00099662250.061
guanosine containing compound catabolic processGO:190106920.061
cellular protein catabolic processGO:004425740.060
cell surface receptor signaling pathwayGO:00071663250.059
regulation of cellular macromolecule biosynthetic processGO:20001122220.059
cell projection organizationGO:00300302840.058
positive regulation of cellular catabolic processGO:003133130.058
negative regulation of biological processGO:00485193040.057
Mouse
regulation of cytokine productionGO:000181730.057
proteolysisGO:0006508380.056
gtp catabolic processGO:000618420.056
organelle organizationGO:00069962270.056
regulation of gtpase activityGO:004308720.056
aromatic compound biosynthetic processGO:00194382170.056
carbohydrate derivative metabolic processGO:1901135610.055
blood vessel morphogenesisGO:00485142160.055
Mouse
modification dependent protein catabolic processGO:001994130.053
biosynthetic processGO:00090582940.053
positive regulation of purine nucleotide catabolic processGO:003312310.051
innate immune response activating signal transductionGO:000275850.050
positive regulation of wound healingGO:009030310.050
cellular response to external stimulusGO:007149620.050
response to vitaminGO:003327330.049
blood vessel developmentGO:00015682460.049
Mouse
oxidoreduction coenzyme metabolic processGO:000673310.049
heart developmentGO:00075073130.048
skeletal system morphogenesisGO:00487051020.047
positive regulation of gtpase activityGO:004354710.047
ameboidal type cell migrationGO:00016671430.047
g protein coupled receptor signaling pathwayGO:0007186740.046
regulation of phosphate metabolic processGO:0019220430.044
cellular response to endogenous stimulusGO:0071495680.044
protein metabolic processGO:00195381830.044
regulation of protein ubiquitinationGO:003139630.043
cellular catabolic processGO:0044248270.043
response to other organismGO:0051707970.043
system processGO:00030081850.043
positive regulation of cell activationGO:005086710.042
cellular response to chemical stimulusGO:00708871570.042
embryonic skeletal system developmentGO:0048706970.041
fin developmentGO:0033333770.041
apoptotic process involved in developmentGO:190274220.041
cellular respirationGO:004533330.041
lens fiber cell developmentGO:007030730.040
cell adhesion mediated by integrinGO:003362710.040
regulation of cell communicationGO:00106462320.039
macromolecular complex subunit organizationGO:0043933740.038
positive regulation of nucleotide catabolic processGO:003081310.038
phosphate containing compound metabolic processGO:00067961080.038
muscle attachmentGO:001620390.038
modification dependent macromolecule catabolic processGO:004363230.038
regulation of hormone secretionGO:004688320.037
cell cycleGO:0007049930.037
regulation of phosphorus metabolic processGO:0051174430.037
neuroblast proliferationGO:000740520.036
signal transductionGO:00071654550.035
microtubule based processGO:0007017600.035
epithelial cell morphogenesisGO:000338220.035
positive regulation of blood circulationGO:190352420.034
cytoskeleton dependent cytokinesisGO:006164030.034
ubiquitin dependent protein catabolic processGO:000651130.034
catabolic processGO:0009056320.034
nucleic acid metabolic processGO:00903042440.034
protein modification processGO:00362111000.034
protein alkylationGO:0008213130.033
proteolysis involved in cellular protein catabolic processGO:005160330.033
positive regulation of protein kinase b signalingGO:005189710.032
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.032
ribonucleotide metabolic processGO:0009259270.032
chemotaxisGO:00069351040.032
neuron projection developmentGO:00311751800.032
positive regulation of gtp catabolic processGO:003312610.032
protein stabilizationGO:005082120.032
gene expressionGO:00104672520.032
response to chemicalGO:00422213200.032
regulation of cytokine biosynthetic processGO:004203510.031
negative regulation of mitosisGO:004583930.031
transportGO:00068102200.031
organic substance catabolic processGO:1901575280.030
methylationGO:0032259220.030
phagocytosisGO:000690930.030
somite developmentGO:0061053960.030
regulation of rna metabolic processGO:00512522240.029
neuronal action potentialGO:0019228180.029
positive regulation of cellular biosynthetic processGO:0031328680.029
cell maturationGO:0048469230.029
regulation of protein modification by small protein conjugation or removalGO:190332030.029
cytokine metabolic processGO:004210710.028
regulation of cellular protein metabolic processGO:0032268520.028
epithelial cell proliferation involved in liver morphogenesisGO:007257520.028
positive regulation of nucleoside metabolic processGO:004597910.028
regulation of cellular metabolic processGO:00313233200.027
regenerationGO:0031099910.027
optic placode formation involved in camera type eye formationGO:004661930.027
lateral line developmentGO:0048882660.027
response to bacteriumGO:0009617580.026
histone modificationGO:0016570200.026
cell substrate junction assemblyGO:000704420.026
single fertilizationGO:000733830.026
positive regulation of translationGO:004572710.026
cellular protein metabolic processGO:00442671290.026
regulation of neuron differentiationGO:0045664560.026
oocyte maturationGO:000155640.026
primary neural tube formationGO:001402010.026
regulation of wound healingGO:006104120.026
positive regulation of cell cycleGO:004578730.025
stem cell maintenanceGO:001982740.025
macromolecule modificationGO:00434121110.025
intracellular estrogen receptor signaling pathwayGO:003052030.025
growth plate cartilage developmentGO:000341720.025
cell part morphogenesisGO:00329902460.025
smoothened signaling pathwayGO:0007224300.025
positive regulation of cytokine productionGO:000181920.025
cilium movementGO:0003341260.025
synaptic target recognitionGO:000803910.024
notochord cell differentiationGO:0060034180.024
small molecule catabolic processGO:004428230.024
skin developmentGO:0043588540.024
regulation of hydrolase activityGO:0051336280.024
skeletal muscle organ developmentGO:0060538780.023
regulation of circadian rhythmGO:004275240.023
cellular response to fibroblast growth factor stimulusGO:0044344220.023
regulation of nucleic acid templated transcriptionGO:19035062130.023
endothelium developmentGO:0003158250.023
regulation of cellular response to growth factor stimulusGO:0090287350.023
response to biotic stimulusGO:0009607970.023
guanosine containing compound metabolic processGO:190106840.023
transmission of nerve impulseGO:0019226190.022
3 utr mediated mrna stabilizationGO:007093530.022
carboxylic acid metabolic processGO:0019752220.022
fibroblast growth factor receptor signaling pathwayGO:0008543220.022
nucleic acid templated transcriptionGO:00976591810.022
regulation of nervous system developmentGO:0051960900.022
positive regulation of multicellular organismal processGO:0051240520.022
alcohol biosynthetic processGO:004616520.022
striated muscle cell developmentGO:00550021080.022
developmental programmed cell deathGO:001062340.022
positive regulation of metabolic processGO:00098931080.022
regulation of sequestering of calcium ionGO:005128240.022
neural plate pattern specificationGO:0060896120.022
cyclic nucleotide metabolic processGO:0009187180.021
skeletal muscle tissue developmentGO:0007519670.021
muscle cell differentiationGO:00426921390.021
response to transition metal nanoparticleGO:1990267280.021
water homeostasisGO:003010440.021
regulation of fatty acid metabolic processGO:001921710.021
cell deathGO:00082191210.021
regulation of extrinsic apoptotic signaling pathwayGO:200123630.021
peptidyl lysine methylationGO:001802230.021
lymphatic endothelial cell differentiationGO:006083610.021
cellular response to molecule of bacterial originGO:007121930.021
immune system developmentGO:00025201910.021
negative regulation of cellular processGO:00485232830.020
actin filament based movementGO:003004810.020
positive regulation of i kappab kinase nf kappab signalingGO:004312330.020
tube closureGO:006060610.020
single organism metabolic processGO:00447102170.020
catecholamine metabolic processGO:000658420.020
ras protein signal transductionGO:000726570.020
regulation of cell shapeGO:000836010.020
cellular response to stressGO:0033554620.020
ribose phosphate metabolic processGO:0019693270.020
organic cyclic compound catabolic processGO:1901361150.019
response to growth factorGO:0070848390.019
proteasomal protein catabolic processGO:001049820.019
cellular component morphogenesisGO:00329893360.019
neural tube developmentGO:0021915620.019
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124010.019
microtubule cytoskeleton organizationGO:0000226330.019
single organism organelle organizationGO:19025891990.019
axon regenerationGO:0031103140.019
regulation of mrna processingGO:005068430.018
eye field cell fate commitment involved in camera type eye formationGO:006089830.018
cellular amino acid metabolic processGO:000652070.018
positive regulation of nucleobase containing compound metabolic processGO:0045935690.018
positive regulation of molecular functionGO:0044093330.018
fin morphogenesisGO:0033334530.018
cellular component assemblyGO:00226071700.018
regulation of autophagyGO:001050630.017
sensory perception of chemical stimulusGO:000760630.017
tube morphogenesisGO:00352393490.017
regulation of bindingGO:005109830.017
signal transduction in absence of ligandGO:003803410.017
regulation of protein metabolic processGO:0051246560.017
response to axon injuryGO:0048678140.017
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377100.017
growthGO:00400071740.017
regulation of ras gtpase activityGO:003231820.017
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.017
membrane invaginationGO:001032410.017
head developmentGO:00603223030.016
cellular response to starvationGO:000926710.016
posterior lateral line neuromast primordium migrationGO:0048920120.016
segmentationGO:0035282970.016
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.016
ribonucleoside metabolic processGO:0009119110.016
extrinsic apoptotic signaling pathwayGO:009719130.016
regulation of cell matrix adhesionGO:000195210.016
anterior commissure morphogenesisGO:002196030.016
i kappab kinase nf kappab signalingGO:000724940.016
cellular nitrogen compound catabolic processGO:0044270150.016
heterocycle biosynthetic processGO:00181302150.016
cell morphogenesis involved in differentiationGO:00009041950.016
embryonic neurocranium morphogenesisGO:0048702150.016
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.015
regulation of organelle organizationGO:0033043290.015
cellular response to hormone stimulusGO:0032870390.015
positive regulation of cell adhesionGO:004578510.015
regulation of macromolecule biosynthetic processGO:00105562250.015
brain developmentGO:00074202930.015
cell matrix adhesionGO:000716040.015
developmental maturationGO:0021700340.015
cellular response to oxygen levelsGO:007145310.015
intracellular signal transductionGO:0035556850.015
lipid homeostasisGO:005508830.015
positive regulation of apoptotic signaling pathwayGO:200123510.015
striated muscle cell differentiationGO:00511461290.015
regulation of cell activationGO:005086510.015
nitric oxide biosynthetic processGO:000680920.015
lens morphogenesis in camera type eyeGO:000208970.015
cellular response to growth factor stimulusGO:0071363390.015
organic acid catabolic processGO:001605430.015
regulation of chemotaxisGO:0050920180.015
axon ensheathment in central nervous systemGO:003229120.014
ventral midline developmentGO:0007418130.014
cell migrationGO:00164772370.014
regulation of cellular biosynthetic processGO:00313262450.014
regulation of cellular ketone metabolic processGO:001056570.014
cognitionGO:005089010.014
endochondral bone growthGO:000341620.014
sensory system developmentGO:0048880760.014
positive regulation of ras gtpase activityGO:003232010.014
anterior head developmentGO:009706520.014
macromolecule biosynthetic processGO:00090592270.014
lens fiber cell morphogenesisGO:007030930.014
regulation of localizationGO:00328791040.014
cell projection morphogenesisGO:00488582440.014
dopamine biosynthetic processGO:004241620.014
endocardium morphogenesisGO:000316040.014
transcription from rna polymerase iii promoterGO:000638310.013
digestive system developmentGO:00551232890.013
rostrocaudal neural tube patterningGO:0021903290.013
regulation of blood vessel sizeGO:005088020.013
transcription dna templatedGO:00063511810.013
protein complex subunit organizationGO:0071822460.013
regulation of hemostasisGO:190004610.013
regulation of microtubule cytoskeleton organizationGO:007050730.013
purine nucleotide metabolic processGO:0006163270.013
protein localization to plasma membraneGO:007265910.013
rna metabolic processGO:00160702190.013
positive regulation of secretionGO:005104710.013
endothelial cell differentiationGO:0045446200.013
regulation of tube sizeGO:003515020.013
oxoacid metabolic processGO:0043436310.013
lymphangiogenesisGO:0001946250.013
negative regulation of signal transduction in absence of ligandGO:190109910.013
regulation of coagulationGO:005081820.013
ectodermal placode developmentGO:0071696370.012
positive regulation of hydrolase activityGO:0051345130.012
stem cell proliferationGO:007208940.012
regulation of carbohydrate metabolic processGO:000610940.012
embryonic organ morphogenesisGO:00485622740.012
positive regulation of cell communicationGO:0010647560.012
sequestering of calcium ionGO:005120830.012
regulation of erk1 and erk2 cascadeGO:007037240.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.012
negative regulation of organelle organizationGO:001063940.012
phagocytosis engulfmentGO:000691110.012
muscle cell developmentGO:00550011150.012
regulation of extent of cell growthGO:0061387290.012
determination of bilateral symmetryGO:00098552040.012
negative regulation of protein kinase b signalingGO:005189820.012
regulation of purine nucleotide metabolic processGO:1900542170.012
response to endogenous stimulusGO:0009719830.012
hematopoietic or lymphoid organ developmentGO:00485341910.011
cellular ketone metabolic processGO:0042180110.011
negative regulation of sequestering of calcium ionGO:005128340.011
endothelial cell fate commitmentGO:006083930.011
sensory organ developmentGO:00074233930.011
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.011
regulation of biosynthetic processGO:00098892500.011
covalent chromatin modificationGO:0016569200.011
single organism membrane fusionGO:004480120.011
extracellular matrix organizationGO:0030198270.011
single organism biosynthetic processGO:0044711710.011
negative regulation of intracellular signal transductionGO:1902532220.011
deathGO:00162651210.011
organic cyclic compound biosynthetic processGO:19013622230.011
positive regulation of multi organism processGO:004390230.011
basement membrane assemblyGO:007083130.011
response to stressGO:00069502630.011
regulation of chromosome segregationGO:005198310.011
cell proliferationGO:0008283800.011
phosphorylationGO:0016310690.011
locomotionGO:00400113130.011
regulation of cellular carbohydrate metabolic processGO:001067540.011
cellular component movementGO:00069283350.011
regulation of transcription from rna polymerase iii promoterGO:000635910.011
modulation by virus of host morphology or physiologyGO:001904810.011
specification of symmetryGO:00097992040.011
muscle tissue developmentGO:00605371100.011
embryonic skeletal system morphogenesisGO:0048704930.011
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.011
regulation of receptor activityGO:001046920.010
positive regulation of cytokine biosynthetic processGO:004210810.010
negative regulation of apoptotic processGO:0043066550.010
somatic muscle developmentGO:000752540.010
neurotransmitter secretionGO:000726920.010
regulation of cellular amine metabolic processGO:003323800.010
cell cycle processGO:0022402530.010
sprouting angiogenesisGO:0002040530.010
epithelial cell morphogenesis involved in gastrulationGO:000338110.010
regulation of endothelial cell proliferationGO:000193610.010
posterior lateral line developmentGO:0048916380.010
carbohydrate homeostasisGO:003350010.010
nuclear divisionGO:0000280230.010
small gtpase mediated signal transductionGO:000726480.010
positive regulation of nitrogen compound metabolic processGO:0051173690.010
positive regulation of macromolecule metabolic processGO:0010604930.010
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.010
ossificationGO:0001503230.010
response to fibroblast growth factorGO:0071774220.010
regulation of rna splicingGO:004348480.010
protein methylationGO:0006479130.010

optc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.027
bone diseaseDOID:008000100.027
disease of anatomical entityDOID:700.027
connective tissue diseaseDOID:6500.027
bone development diseaseDOID:008000600.027
nervous system diseaseDOID:86300.020
eye and adnexa diseaseDOID:149200.015
sensory system diseaseDOID:005015500.015
eye diseaseDOID:561400.015
dysostosisDOID:193400.011