Danio rerio

19 known processes

pnn

pinin, desmosome associated protein

(Aliases: wu:fb24d03)

pnn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
alternative mrna splicing via spliceosomeGO:000038010.546
cellular macromolecule metabolic processGO:00442603910.134
immune system processGO:00023762410.132
positive regulation of cellular component biogenesisGO:004408930.115
larval developmentGO:000216420.111
regulation of mrna splicing via spliceosomeGO:004802430.103
negative regulation of gene expressionGO:0010629650.099
regulation of mrna processingGO:005068430.087
embryo development ending in birth or egg hatchingGO:00097922710.085
regulation of rna metabolic processGO:00512522240.079
proteolysis involved in cellular protein catabolic processGO:005160330.076
regulation of cellular metabolic processGO:00313233200.075
stem cell maintenanceGO:001982740.073
regulation of alternative mrna splicing via spliceosomeGO:000038110.069
regulation of nucleobase containing compound metabolic processGO:00192192500.067
gene expressionGO:00104672520.065
regulation of nitrogen compound metabolic processGO:00511712510.065
meiotic nuclear divisionGO:000712640.065
heterocycle biosynthetic processGO:00181302150.063
organic cyclic compound biosynthetic processGO:19013622230.063
cellular protein catabolic processGO:004425740.059
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377100.059
regulation of gene expressionGO:00104682650.058
protein metabolic processGO:00195381830.057
rna biosynthetic processGO:00327741810.057
cellular aromatic compound metabolic processGO:00067252950.056
regulation of primary metabolic processGO:00800903110.055
organic cyclic compound metabolic processGO:19013603010.054
cellular macromolecule biosynthetic processGO:00346452240.052
regulation of cellular biosynthetic processGO:00313262450.052
adult behaviorGO:003053420.051
agingGO:000756820.048
multicellular organism growthGO:003526440.046
regulation of meiotic cell cycleGO:005144510.045
maintenance of locationGO:005123540.045
nucleic acid metabolic processGO:00903042440.044
regulation of mrna metabolic processGO:190331160.043
hematopoietic or lymphoid organ developmentGO:00485341910.043
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.042
ubiquitin dependent protein catabolic processGO:000651130.041
embryonic organ morphogenesisGO:00485622740.039
transcription from rna polymerase ii promoterGO:0006366800.039
regulation of rna splicingGO:004348480.039
organic substance biosynthetic processGO:19015762890.038
synaptic growth at neuromuscular junctionGO:005112420.038
establishment of protein localization to organelleGO:007259440.037
nucleobase containing compound metabolic processGO:00061392740.037
macromolecule biosynthetic processGO:00090592270.037
cellular nitrogen compound biosynthetic processGO:00442712180.036
rna metabolic processGO:00160702190.035
stem cell developmentGO:0048864820.035
chordate embryonic developmentGO:00430092710.034
negative regulation of ras protein signal transductionGO:004658010.034
negative regulation of metabolic processGO:0009892860.034
positive regulation of cell cycleGO:004578730.034
immune system developmentGO:00025201910.033
response to drugGO:004249330.033
cellular biosynthetic processGO:00442492860.033
regulation of developmental processGO:00507932470.031
regulation of macromolecule metabolic processGO:00602553170.031
regulation of transcription dna templatedGO:00063552130.031
rna splicing via transesterification reactionsGO:0000375100.030
negative regulation of cellular processGO:00485232830.030
rna splicingGO:0008380160.030
skeletal system developmentGO:00015011810.029
transportGO:00068102200.029
macromolecule methylationGO:0043414190.029
regulation of multicellular organism growthGO:004001440.029
negative regulation of macromolecule metabolic processGO:0010605760.029
locomotionGO:00400113130.028
striated muscle cell differentiationGO:00511461290.028
cellular protein metabolic processGO:00442671290.028
central nervous system neuron differentiationGO:0021953740.028
regulation of biological qualityGO:00650082630.028
spliceosomal complex assemblyGO:000024510.027
heterocycle metabolic processGO:00464832900.027
positive regulation of chromatin modificationGO:190331010.027
protein importGO:001703830.027
transcription dna templatedGO:00063511810.027
nuclear importGO:005117030.027
stem cell proliferationGO:007208940.026
carboxylic acid metabolic processGO:0019752220.026
cellular component morphogenesisGO:00329893360.026
proteasomal protein catabolic processGO:001049820.026
regulation of metabolic processGO:00192223590.026
regulation of rna biosynthetic processGO:20011412130.025
regulation of histone methylationGO:003106030.025
positive regulation of biological processGO:00485182530.025
positive regulation of synapse assemblyGO:005196510.024
negative regulation of biological processGO:00485193040.024
histone h4 k20 methylationGO:003477020.024
aromatic compound biosynthetic processGO:00194382170.024
protein targeting to nucleusGO:004474430.024
heart developmentGO:00075073130.023
somitogenesisGO:0001756870.023
modification dependent macromolecule catabolic processGO:004363230.023
positive regulation of histone modificationGO:003105810.023
regulation of synapse organizationGO:005080730.023
negative regulation of catabolic processGO:000989530.023
signal transductionGO:00071654550.023
regulation of protein catabolic processGO:004217610.023
generation of neuronsGO:00486993850.022
regulation of synapse assemblyGO:005196330.022
positive regulation of chromosome organizationGO:200125210.022
negative regulation of cellular metabolic processGO:0031324770.022
hemopoiesisGO:00300971830.022
regulation of cellular macromolecule biosynthetic processGO:20001122220.022
nucleocytoplasmic transportGO:000691340.022
programmed cell deathGO:00125011190.022
regulation of nucleic acid templated transcriptionGO:19035062130.021
regulation of synaptic growth at neuromuscular junctionGO:000858210.021
stem cell differentiationGO:00488631170.021
regulation of cell deathGO:00109411030.021
protein stabilizationGO:005082120.020
positive regulation of dna metabolic processGO:005105410.020
nucleobase containing compound biosynthetic processGO:00346542050.020
positive regulation of cellular amino acid metabolic processGO:004576400.020
biosynthetic processGO:00090582940.019
rna processingGO:0006396250.019
modification of morphology or physiology of other organismGO:003582140.019
regulation of mrna catabolic processGO:006101330.019
neuron developmentGO:00486662620.019
regulation of intracellular protein transportGO:003315730.019
hematopoietic stem cell differentiationGO:0060218200.019
transcription from rna polymerase iii promoterGO:000638310.019
regulation of transcription from rna polymerase ii promoterGO:00063571140.019
compound eye developmentGO:004874920.019
erythrocyte maturationGO:004324980.019
cellular nitrogen compound metabolic processGO:00346412900.019
dorsal ventral pattern formationGO:00099531250.018
b cell mediated immunityGO:001972430.018
protein acylationGO:004354330.018
macromolecule localizationGO:0033036540.018
nitrogen compound metabolic processGO:00068073190.018
response to chemicalGO:00422213200.018
positive regulation of transportGO:005105020.018
histone h3 k4 methylationGO:005156820.018
growthGO:00400071740.018
nuclear transportGO:005116940.018
localization of cellGO:00516742440.018
cellular component assemblyGO:00226071700.018
protein import into nucleusGO:000660630.018
modification dependent protein catabolic processGO:001994130.017
lipid storageGO:001991510.017
regulation of macromolecule biosynthetic processGO:00105562250.017
positive regulation of rna metabolic processGO:0051254590.017
head developmentGO:00603223030.017
positive regulation of cellular amine metabolic processGO:003324000.017
somite developmentGO:0061053960.017
hepaticobiliary system developmentGO:0061008980.017
posterior lateral line system developmentGO:0048915460.017
negative regulation of dna templated transcription elongationGO:003278510.017
amine metabolic processGO:000930820.017
cell morphogenesisGO:00009022890.016
negative regulation of defense responseGO:003134820.016
cellular component assembly involved in morphogenesisGO:00109271070.016
positive regulation of developmental processGO:0051094500.016
intracellular estrogen receptor signaling pathwayGO:003052030.016
cellular component biogenesisGO:00440851780.016
negative regulation of rna splicingGO:003311910.016
rna export from nucleusGO:000640510.016
symbiosis encompassing mutualism through parasitismGO:004440340.016
primary neural tube formationGO:001402010.016
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.016
regulation of response to stimulusGO:00485832690.016
rna transportGO:005065820.016
myeloid cell differentiationGO:0030099860.015
regulation of gene expression epigeneticGO:0040029110.015
myeloid cell homeostasisGO:0002262560.015
positive regulation of metabolic processGO:00098931080.015
determination of bilateral symmetryGO:00098552040.015
digestive tract developmentGO:00485652650.015
embryonic skeletal joint morphogenesisGO:006027230.015
positive regulation of rna biosynthetic processGO:1902680570.015
epithelial cell differentiationGO:00308551160.015
peptidyl lysine monomethylationGO:001802610.015
embryonic skeletal system developmentGO:0048706970.015
regulation of establishment of protein localizationGO:007020140.015
neuron differentiationGO:00301823530.014
negative regulation of nucleocytoplasmic transportGO:004682320.014
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.014
erythrocyte homeostasisGO:0034101550.014
regulation of cellular amine metabolic processGO:003323800.014
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.014
mesenchymal cell differentiationGO:0048762870.014
positive regulation of gliogenesisGO:001401520.014
regulation of cellular protein catabolic processGO:190336210.014
peptidyl lysine methylationGO:001802230.014
negative regulation of histone modificationGO:003105710.014
regulation of response to cytokine stimulusGO:006075930.014
embryonic heart tube developmentGO:00350501330.014
adherens junction organizationGO:003433240.014
negative regulation of chromosome organizationGO:200125110.014
dna biosynthetic processGO:007189730.014
positive regulation of cellular catabolic processGO:003133130.014
regulation of stem cell differentiationGO:200073640.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.013
regulation of histone h3 k9 methylationGO:005157020.013
regulation of glial cell differentiationGO:004568540.013
single organism nuclear importGO:190259330.013
regulation of nucleocytoplasmic transportGO:004682220.013
morphogenesis of an epitheliumGO:00020093330.013
positive regulation of catabolic processGO:000989640.013
cell projection organizationGO:00300302840.013
negative regulation of dna metabolic processGO:005105340.013
embryonic cranial skeleton morphogenesisGO:0048701900.013
cell deathGO:00082191210.013
negative regulation of dna replicationGO:000815620.013
positive regulation of nitrogen compound metabolic processGO:0051173690.013
sex determinationGO:000753010.013
phagocytosisGO:000690930.013
sensory organ developmentGO:00074233930.013
peptidyl lysine acetylationGO:001839420.013
heart morphogenesisGO:00030071560.013
regionalizationGO:00030022740.012
regulation of cytoplasmic transportGO:190364940.012
regulation of dna templated transcription elongationGO:003278430.012
cellular response to external stimulusGO:007149620.012
oxoacid metabolic processGO:0043436310.012
determination of heart left right asymmetryGO:00613711170.012
negative regulation of biosynthetic processGO:0009890550.012
homeostasis of number of cellsGO:0048872620.012
nucleic acid templated transcriptionGO:00976591810.012
response to hexoseGO:000974630.012
regulation of cytokine mediated signaling pathwayGO:000195930.012
skeletal system morphogenesisGO:00487051020.012
mitotic cell cycle embryonicGO:004544820.012
regulation of cell activationGO:005086510.012
protein acetylationGO:000647320.012
response to corticosteroidGO:003196010.012
protein polyubiquitinationGO:000020940.012
cilium morphogenesisGO:0060271850.012
single organism organelle organizationGO:19025891990.012
interspecies interaction between organismsGO:004441940.012
central nervous system developmentGO:00074173870.012
germ line stem cell maintenanceGO:003071820.011
regulation of protein complex assemblyGO:004325430.011
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.011
regulation of skeletal muscle tissue developmentGO:004864140.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
mesenchyme developmentGO:00604851270.011
rna localizationGO:000640340.011
regulation of multicellular organismal developmentGO:20000262230.011
viral processGO:001603210.011
positive regulation of carbohydrate metabolic processGO:004591310.011
positive regulation of dna templated transcription elongationGO:003278610.011
negative regulation of cellular catabolic processGO:003133030.011
specification of symmetryGO:00097992040.011
muscle tissue developmentGO:00605371100.011
b cell activationGO:004211320.011
nucleic acid transportGO:005065720.011
pharyngeal muscle developmentGO:004328240.011
small gtpase mediated signal transductionGO:000726480.011
embryonic skeletal system morphogenesisGO:0048704930.011
cellular amine metabolic processGO:004410620.011
neuronal stem cell maintenanceGO:009715020.011
mesenchymal cell developmentGO:0014031780.011
establishment of rna localizationGO:005123630.011
positive regulation of mrna metabolic processGO:190331320.011
anterior posterior pattern specificationGO:00099521520.011
ras protein signal transductionGO:000726570.011
cellular protein modification processGO:00064641000.011
cell cycleGO:0007049930.011
posterior lateral line developmentGO:0048916380.011
nuclear migrationGO:000709730.011
dna templated transcription elongationGO:000635430.011
cell motilityGO:00488702440.011
gland developmentGO:00487321430.011
positive regulation of small gtpase mediated signal transductionGO:005105710.010
deathGO:00162651210.010
regulation of epidermis developmentGO:004568220.010
positive regulation of macromolecule metabolic processGO:0010604930.010
hematopoietic progenitor cell differentiationGO:0002244230.010
cellular component disassemblyGO:002241110.010
regulation of multicellular organismal processGO:00512392770.010
neuroblast proliferationGO:000740520.010
negative regulation of multi organism processGO:004390130.010
regulation of growth rateGO:004000910.010
mrna metabolic processGO:0016071200.010
regulation of programmed cell deathGO:00430671010.010

pnn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.044
motor neuron diseaseDOID:23100.025
neurodegenerative diseaseDOID:128900.025
nervous system diseaseDOID:86300.025
amyotrophic lateral sclerosisDOID:33200.025
central nervous system diseaseDOID:33100.025
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011