Danio rerio

36 known processes

gsk3b

glycogen synthase kinase 3 beta

(Aliases: wu:fk80d11,fk80d11,GSK-3[b],GSK3,wu:fb68h05)

gsk3b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of transportGO:005105020.248
cellular macromolecule metabolic processGO:00442603910.216
cellular component movementGO:00069283350.168
larval developmentGO:000216420.160
regulation of cellular metabolic processGO:00313233200.144
rna biosynthetic processGO:00327741810.138
single organism localizationGO:19025782250.133
response to chemicalGO:00422213200.122
regulation of protein complex assemblyGO:004325430.119
segmentationGO:0035282970.115
cell morphogenesis involved in neuron differentiationGO:00486671630.108
organic cyclic compound metabolic processGO:19013603010.101
response to drugGO:004249330.099
endosomal transportGO:001619720.099
regulation of protein polymerizationGO:003227120.095
actin polymerization or depolymerizationGO:000815420.092
meiotic nuclear divisionGO:000712640.089
regulation of developmental processGO:00507932470.089
multicellular organism growthGO:003526440.088
cellular component morphogenesisGO:00329893360.087
cell motilityGO:00488702440.087
protein metabolic processGO:00195381830.085
transportGO:00068102200.084
regulation of multicellular organismal developmentGO:20000262230.082
neuron differentiationGO:00301823530.082
response to external stimulusGO:00096052640.081
cellular aromatic compound metabolic processGO:00067252950.080
regulation of macromolecule biosynthetic processGO:00105562250.080
positive regulation of biological processGO:00485182530.079
neuron developmentGO:00486662620.079
protein import into nucleusGO:000660630.078
cell part morphogenesisGO:00329902460.077
cell migrationGO:00164772370.076
protein polymerizationGO:005125840.075
single organism metabolic processGO:00447102170.074
transcription from rna polymerase ii promoterGO:0006366800.074
positive regulation of cell cycleGO:004578730.073
positive regulation of protein complex assemblyGO:003133420.071
heart developmentGO:00075073130.071
single organism transportGO:00447652060.071
positive regulation of catabolic processGO:000989640.070
regulation of multicellular organism growthGO:004001440.070
actin filament polymerizationGO:003004120.070
autophagyGO:000691440.070
anterior posterior pattern specificationGO:00099521520.068
regulation of synapse assemblyGO:005196330.067
nucleobase containing compound biosynthetic processGO:00346542050.067
nuclear transportGO:005116940.067
regulation of metabolic processGO:00192223590.066
small molecule metabolic processGO:0044281770.066
exocytosisGO:000688710.065
positive regulation of secretion by cellGO:190353210.065
cell morphogenesisGO:00009022890.065
organic substance biosynthetic processGO:19015762890.064
synaptic vesicle localizationGO:009747910.064
lamellipodium organizationGO:009758110.063
axonogenesisGO:00074091520.062
locomotionGO:00400113130.062
cellular nitrogen compound metabolic processGO:00346412900.061
macromolecule biosynthetic processGO:00090592270.059
regulation of nitrogen compound metabolic processGO:00511712510.059
regulation of primary metabolic processGO:00800903110.058
nitrogen compound metabolic processGO:00068073190.058
chemotaxisGO:00069351040.057
regulation of nucleobase containing compound metabolic processGO:00192192500.056
cellular response to chemical stimulusGO:00708871570.055
phagocytosis engulfmentGO:000691110.054
synaptic vesicle transportGO:004848910.054
nucleic acid templated transcriptionGO:00976591810.054
membrane invaginationGO:001032410.053
agingGO:000756820.053
regulation of synapse organizationGO:005080730.053
cytokinesisGO:000091030.053
regulation of cellular amino acid metabolic processGO:000652100.053
neuron projection morphogenesisGO:00488121610.052
aromatic compound biosynthetic processGO:00194382170.052
gtp catabolic processGO:000618420.052
embryo development ending in birth or egg hatchingGO:00097922710.052
neuron projection developmentGO:00311751800.052
regulation of macromolecule metabolic processGO:00602553170.051
vesicle localizationGO:0051648270.051
guanosine containing compound catabolic processGO:190106920.051
cellular component assemblyGO:00226071700.051
regulation of dendrite morphogenesisGO:004881430.051
lamellipodium assemblyGO:003003210.051
positive regulation of cell killingGO:003134320.051
meiotic cell cycle processGO:190304630.051
stem cell maintenanceGO:001982740.051
cell projection morphogenesisGO:00488582440.050
cell surface receptor signaling pathwayGO:00071663250.050
cellular carbohydrate metabolic processGO:004426240.050
cellular response to lipopolysaccharideGO:007122230.050
positive regulation of secretionGO:005104710.050
ubiquitin dependent protein catabolic processGO:000651130.049
somite developmentGO:0061053960.048
cell projection organizationGO:00300302840.048
regulation of natural killer cell mediated immunityGO:000271510.048
regulation of protein modification by small protein conjugation or removalGO:190332030.047
regulation of response to nutrient levelsGO:003210710.047
positive regulation of cellular component biogenesisGO:004408930.047
protein targeting to nucleusGO:004474430.047
cytoplasm organizationGO:000702840.047
regulation of gene expressionGO:00104682650.047
vacuolar transportGO:000703420.047
establishment of protein localization to organelleGO:007259440.046
post golgi vesicle mediated transportGO:000689210.046
muscle cell migrationGO:001481240.045
enzyme linked receptor protein signaling pathwayGO:00071671060.045
regulation of cellular response to growth factor stimulusGO:0090287350.045
cellular response to nutrient levelsGO:003166920.045
single organism organelle organizationGO:19025891990.045
regulation of rna metabolic processGO:00512522240.045
localization of cellGO:00516742440.044
cellular nitrogen compound biosynthetic processGO:00442712180.044
single organism nuclear importGO:190259330.044
organic acid metabolic processGO:0006082310.044
heterocycle biosynthetic processGO:00181302150.044
transcription dna templatedGO:00063511810.044
regulation of bindingGO:005109830.043
regulation of response to stimulusGO:00485832690.043
positive regulation of leukocyte mediated cytotoxicityGO:000191210.043
establishment of synaptic vesicle localizationGO:009748010.043
small molecule catabolic processGO:004428230.043
regulation of cellular carbohydrate metabolic processGO:001067540.042
oxoacid metabolic processGO:0043436310.042
positive regulation of lymphocyte mediated immunityGO:000270810.042
organonitrogen compound metabolic processGO:1901564740.042
protein localization to plasma membraneGO:007265910.042
somitogenesisGO:0001756870.042
heart contractionGO:0060047710.042
positive regulation of cellular processGO:00485222010.042
heart morphogenesisGO:00030071560.042
rna metabolic processGO:00160702190.042
modification dependent macromolecule catabolic processGO:004363230.041
gtp metabolic processGO:004603940.041
guanosine containing compound metabolic processGO:190106840.041
cellular component biogenesisGO:00440851780.041
development of primary female sexual characteristicsGO:004654540.040
regulation of exocytosisGO:001715710.040
i kappab kinase nf kappab signalingGO:000724940.040
neurotransmitter transportGO:000683620.039
axon guidanceGO:0007411860.039
centrosome organizationGO:005129710.039
female gonad developmentGO:000858540.039
synaptic growth at neuromuscular junctionGO:005112420.039
negative regulation of cellular processGO:00485232830.039
regulation of anatomical structure morphogenesisGO:00226031300.038
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.038
muscle structure developmentGO:00610611960.037
regulation of transcription dna templatedGO:00063552130.037
intracellular transportGO:0046907320.037
morphogenesis of an epitheliumGO:00020093330.037
immune system developmentGO:00025201910.037
negative regulation of protein phosphorylationGO:000193340.037
cellular biosynthetic processGO:00442492860.036
regulation of protein ubiquitinationGO:003139630.036
cellular response to starvationGO:000926710.036
regulation of rna biosynthetic processGO:20011412130.036
regulation of dendrite developmentGO:005077330.036
maintenance of locationGO:005123540.036
cellular response to molecule of bacterial originGO:007121930.035
microtubule organizing center organizationGO:003102310.035
phagocytosisGO:000690930.035
regulation of peptidyl tyrosine phosphorylationGO:005073010.035
regulation of cellular biosynthetic processGO:00313262450.035
positive regulation of cellular catabolic processGO:003133130.035
regulation of biological qualityGO:00650082630.035
proteolysis involved in cellular protein catabolic processGO:005160330.035
taxisGO:00423301090.035
response to other organismGO:0051707970.035
golgi vesicle transportGO:004819330.035
nucleic acid metabolic processGO:00903042440.035
vasculature developmentGO:00019442780.035
negative regulation of response to stimulusGO:00485851040.034
generation of neuronsGO:00486993850.034
positive regulation of immune effector processGO:000269930.034
regulation of synaptic growth at neuromuscular junctionGO:000858210.034
developmental growth involved in morphogenesisGO:0060560860.034
cellular ketone metabolic processGO:0042180110.034
adult behaviorGO:003053420.034
female sex differentiationGO:004666040.033
regulation of localizationGO:00328791040.033
heterocycle metabolic processGO:00464832900.033
cell substrate adhesionGO:003158940.033
immune system processGO:00023762410.033
gene expressionGO:00104672520.033
cellular response to extracellular stimulusGO:003166820.032
regulation of inflammatory responseGO:005072720.032
positive regulation of cytoskeleton organizationGO:005149530.032
regulation of autophagyGO:001050630.032
response to external biotic stimulusGO:0043207970.032
regulation of signalingGO:00230512350.032
regulation of neurogenesisGO:0050767870.032
regulation of biosynthetic processGO:00098892500.032
negative regulation of chromosome organizationGO:200125110.032
natural killer cell mediated immunityGO:000222810.032
cognitionGO:005089010.032
nucleocytoplasmic transportGO:000691340.032
modification dependent protein catabolic processGO:001994130.032
positive regulation of lipid metabolic processGO:004583410.032
blood vessel developmentGO:00015682460.031
regulation of jak stat cascadeGO:004642530.031
cellular response to stressGO:0033554620.031
regulation of signal transductionGO:00099662250.031
developmental growthGO:00485891660.031
regulation of cell shapeGO:000836010.030
cellular pigmentationGO:0033059300.030
positive regulation of protein kinase b signalingGO:005189710.030
negative regulation of multicellular organismal processGO:0051241690.030
regulation of cytokine productionGO:000181730.030
protein localization to nucleusGO:003450430.030
blood circulationGO:0008015870.030
multicellular organismal reproductive processGO:0048609350.030
biosynthetic processGO:00090582940.029
establishment of vesicle localizationGO:0051650240.029
regulation of protein targetingGO:190353320.029
negative regulation of biological processGO:00485193040.029
skeletal muscle organ developmentGO:0060538780.029
regulation of metal ion transportGO:001095940.029
cellular macromolecule biosynthetic processGO:00346452240.029
cellular response to organic substanceGO:00713101050.029
regulation of multicellular organismal processGO:00512392770.029
response to stressGO:00069502630.029
carboxylic acid metabolic processGO:0019752220.028
cellular protein modification processGO:00064641000.028
circadian sleep wake cycle sleepGO:005080210.028
stem cell divisionGO:001714510.028
regulation of carbohydrate metabolic processGO:000610940.028
regulation of protein import into nucleusGO:004230620.028
regulation of cellular ketone metabolic processGO:001056570.028
positive regulation of protein polymerizationGO:003227320.028
olfactory bulb developmentGO:002177240.028
regulation of neurotransmitter transportGO:005158810.028
striated muscle cell developmentGO:00550021080.027
carbohydrate homeostasisGO:003350010.027
cell morphogenesis involved in differentiationGO:00009041950.027
neurotransmitter secretionGO:000726920.027
organelle assemblyGO:00709251100.027
brain developmentGO:00074202930.027
regulation of epithelial cell proliferationGO:005067830.027
negative regulation of synapse assemblyGO:005196420.027
negative regulation of protein kinase activityGO:000646940.027
organic cyclic compound biosynthetic processGO:19013622230.027
negative regulation of kinase activityGO:003367340.027
system processGO:00030081850.026
protein importGO:001703830.026
establishment of localization in cellGO:0051649770.026
positive regulation of exocytosisGO:004592110.026
biological adhesionGO:0022610400.026
peptide transportGO:001583310.026
meiotic chromosome segregationGO:004513230.026
ovulation cycle processGO:002260220.025
striated muscle cell differentiationGO:00511461290.025
cellular protein catabolic processGO:004425740.025
neuron projection guidanceGO:0097485860.025
response to organic substanceGO:00100331530.025
positive regulation of cell adhesionGO:004578510.025
establishment of localizationGO:00512342440.025
circulatory system processGO:0003013870.025
regulation of neurotransmitter secretionGO:004692810.024
fertilizationGO:000956630.024
regulation of protein transportGO:005122330.024
regulation of synaptic plasticityGO:004816710.024
negative regulation of catabolic processGO:000989530.024
neuron neuron synaptic transmissionGO:000727010.024
regulation of protein metabolic processGO:0051246560.024
establishment of protein localization to plasma membraneGO:009000210.024
regulation of nucleic acid templated transcriptionGO:19035062130.024
locomotor rhythmGO:004547530.024
negative regulation of autophagyGO:001050710.024
regulation of protein localization to nucleusGO:190018020.024
regulation of cellular amine metabolic processGO:003323800.024
chordate embryonic developmentGO:00430092710.024
cell adhesionGO:0007155400.024
positive regulation of cellular amine metabolic processGO:003324000.024
regulation of nucleocytoplasmic transportGO:004682220.023
multicellular organismal signalingGO:0035637220.023
regulation of cellular component organizationGO:0051128860.023
dorsal motor nucleus of vagus nerve developmentGO:002174440.023
detection of mechanical stimulus involved in sensory perceptionGO:0050974110.023
cellular response to biotic stimulusGO:007121630.023
regulation of cytoplasmic transportGO:190364940.023
organelle organizationGO:00069962270.023
axon developmentGO:00615641660.023
negative regulation of map kinase activityGO:004340720.023
regulation of protein bindingGO:004339330.023
lateral inhibitionGO:004633110.023
convergent extensionGO:00600261180.023
regulation of cell projection assemblyGO:006049140.023
regulation of response to stressGO:0080134360.023
positive regulation of gtp catabolic processGO:003312610.023
lipid catabolic processGO:001604240.023
cellular protein complex assemblyGO:0043623190.023
protein acylationGO:004354330.023
cortical cytoskeleton organizationGO:003086510.022
regulation of cell killingGO:003134120.022
eye developmentGO:00016542770.022
developmental process involved in reproductionGO:0003006270.022
growthGO:00400071740.022
entrainment of circadian clockGO:000964920.022
regulation of transcription from rna polymerase ii promoterGO:00063571140.022
macromolecule modificationGO:00434121110.022
regionalizationGO:00030022740.022
cellular response to external stimulusGO:007149620.022
oocyte anterior posterior axis specificationGO:000731440.022
response to carbohydrateGO:000974330.022
negative regulation of histone modificationGO:003105710.022
synaptic vesicle recyclingGO:003646510.022
epithelial cell differentiationGO:00308551160.022
adherens junction organizationGO:003433240.022
regulation of cell substrate adhesionGO:001081010.022
glucose homeostasisGO:004259310.022
spermatid differentiationGO:004851520.022
neuromuscular process controlling balanceGO:005088530.022
embryonic organ developmentGO:00485683810.022
intracellular mrna localizationGO:000829810.022
transmission of nerve impulseGO:0019226190.022
germ line stem cell maintenanceGO:003071820.021
nucleobase containing compound metabolic processGO:00061392740.021
central nervous system developmentGO:00074173870.021
cellular component maintenanceGO:004395430.021
axon extensionGO:0048675450.021
pigmentationGO:0043473850.021
sulfur compound metabolic processGO:0006790130.021
negative regulation of protein transportGO:005122430.021
regulation of nucleoside metabolic processGO:000911820.021
head developmentGO:00603223030.021
cellular lipid catabolic processGO:004424230.021
negative regulation of mapk cascadeGO:004340940.021
release of sequestered calcium ion into cytosolGO:005120930.021
positive regulation of i kappab kinase nf kappab signalingGO:004312330.021
fatty acid transportGO:001590810.021
regulation of response to extracellular stimulusGO:003210410.020
ovulation cycleGO:004269820.020
regulation of organelle assemblyGO:190211540.020
single fertilizationGO:000733830.020
positive regulation of nucleoside metabolic processGO:004597910.020
positive regulation of myeloid cell differentiationGO:004563920.020
regulation of filopodium assemblyGO:005148920.020
regulation of erythrocyte differentiationGO:004564620.020
sensory perception of touchGO:005097520.020
regulation of cell activationGO:005086510.020
long chain fatty acid transportGO:001590910.020
cellular protein metabolic processGO:00442671290.020
positive regulation of muscle cell differentiationGO:005114910.020
eye morphogenesisGO:00485921440.020
negative regulation of protein import into nucleusGO:004230820.020
blood vessel morphogenesisGO:00485142160.020
protein modification processGO:00362111000.020
positive regulation of cell activationGO:005086710.020
regulation of cell morphogenesisGO:0022604420.020
regulation of establishment of protein localizationGO:007020140.019
regulation of nervous system developmentGO:0051960900.019
heart processGO:0003015710.019
muscle organ developmentGO:00075171010.019
nuclear importGO:005117030.019
negative regulation of cytoplasmic transportGO:190365020.019
response to biotic stimulusGO:0009607970.019
multi organism processGO:00517041340.019
cellular amine metabolic processGO:004410620.019
regulation of purine nucleotide catabolic processGO:003312120.019
cell deathGO:00082191210.019
cellular response to endogenous stimulusGO:0071495680.019
cellular localizationGO:0051641970.019
leukocyte mediated cytotoxicityGO:000190910.019
myeloid cell developmentGO:0061515320.019
spermatid developmentGO:000728620.019
cytoskeleton organizationGO:0007010960.018
forebrain cell migrationGO:002188510.018
synaptic target recognitionGO:000803910.018
sexual reproductionGO:0019953360.018
somatic stem cell maintenanceGO:003501910.018
stem cell developmentGO:0048864820.018
calcium ion importGO:007050940.018
cell cycleGO:0007049930.018
cell cycle arrestGO:000705010.018
somatic muscle developmentGO:000752540.018
cellular response to oxygen levelsGO:007145310.018
cellular catabolic processGO:0044248270.017
macroautophagyGO:001623610.017
hormone transportGO:000991420.017
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.017
muscle cell developmentGO:00550011150.017
amine metabolic processGO:000930820.017
stem cell proliferationGO:007208940.017
camera type eye developmentGO:00430102220.017
regulation of meiotic cell cycleGO:005144510.017
regulation of calcium ion transportGO:005192420.017
natural killer cell mediated cytotoxicityGO:004226710.017
rna localizationGO:000640340.017
calcium ion dependent exocytosisGO:001715610.017
central nervous system neuron axonogenesisGO:0021955180.017
cellular component disassemblyGO:002241110.017
camera type eye morphogenesisGO:00485931080.017
regulation of i kappab kinase nf kappab signalingGO:004312240.017
macromolecular complex subunit organizationGO:0043933740.017
regulation of gtpase activityGO:004308720.017
negative regulation of protein serine threonine kinase activityGO:007190120.017
positive regulation of leukocyte mediated immunityGO:000270510.017
regulation of skeletal muscle tissue developmentGO:004864140.017
outflow tract morphogenesisGO:000315110.017
energy reserve metabolic processGO:000611220.017
macromolecular complex assemblyGO:0065003350.017
lipid storageGO:001991510.016
regulation of cellular macromolecule biosynthetic processGO:20001122220.016
regulation of intracellular protein transportGO:003315730.016
regulation of erk1 and erk2 cascadeGO:007037240.016
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.016
regulation of cell morphogenesis involved in differentiationGO:0010769380.016
response to metal ionGO:0010038340.016
regulation of molecular functionGO:0065009700.016
cellular component assembly involved in morphogenesisGO:00109271070.016
signal transductionGO:00071654550.016
regulation of nucleotide catabolic processGO:003081120.016
response to monosaccharideGO:003428430.016
negative regulation of cellular catabolic processGO:003133030.016
regulation of cell sizeGO:0008361290.016
negative regulation of intracellular transportGO:003238730.016
organic acid catabolic processGO:001605430.016
macromolecular complex disassemblyGO:003298410.016
protein secretionGO:000930610.016
regulation of membrane potentialGO:0042391230.016
multi organism reproductive processGO:0044703360.016
regulation of cell developmentGO:00602841000.016
protein dephosphorylationGO:000647030.016
regulation of skeletal muscle fiber developmentGO:004874220.016
digestive tract developmentGO:00485652650.016
cellular response to growth factor stimulusGO:0071363390.016
regulation of blood vessel sizeGO:005088020.016
single organism cellular localizationGO:1902580460.015
regulation of response to oxidative stressGO:190288220.015
astrocyte differentiationGO:004870810.015
regulation of stem cell differentiationGO:200073640.015
catabolic processGO:0009056320.015
negative regulation of dna metabolic processGO:005105340.015
protein complex localizationGO:003150310.015
regulation of locomotionGO:0040012550.015
medulla oblongata developmentGO:002155040.015
negative regulation of epithelial cell proliferationGO:005068010.015
negative regulation of metabolic processGO:0009892860.015
positive regulation of gtpase activityGO:004354710.015
neuron remodelingGO:001632210.015
regulation of neuron differentiationGO:0045664560.015
macromolecule localizationGO:0033036540.015
regulation of hormone secretionGO:004688320.015
developmental pigmentationGO:0048066480.015
cortical actin cytoskeleton organizationGO:003086610.015
cardiac cell fate commitmentGO:006091110.015
regulation of blood circulationGO:1903522320.015
regulation of wound healingGO:006104120.015
hormone secretionGO:004687920.015
positive regulation of cell divisionGO:005178120.015
regulation of system processGO:0044057400.015
regulation of reactive oxygen species metabolic processGO:200037720.015
protein heterooligomerizationGO:005129110.015
macromolecule deacylationGO:009873230.015
regulation of mrna splicing via spliceosomeGO:004802430.015
sensory organ morphogenesisGO:00905962000.015
protein complex disassemblyGO:004324110.015
positive regulation of defense responseGO:003134990.014
olfactory lobe developmentGO:002198840.014
regulation of immune system processGO:0002682340.014
regulation of tube sizeGO:003515020.014
negative regulation of ras protein signal transductionGO:004658010.014
neutrophil migrationGO:1990266100.014
regulation of circadian rhythmGO:004275240.014
tube closureGO:006060610.014
response to glucoseGO:000974930.014
sensory organ developmentGO:00074233930.014
positive regulation of nucleotide catabolic processGO:003081310.014
angiogenesisGO:00015251580.014
defense responseGO:0006952470.014
regulation of natural killer cell mediated cytotoxicityGO:004226910.014
myotube differentiationGO:0014902450.014
actin filament based processGO:0030029640.014
phosphate containing compound metabolic processGO:00067961080.014
regulation of neuron projection developmentGO:0010975400.014
protein complex biogenesisGO:0070271300.014
phosphorus metabolic processGO:00067931090.014
establishment or maintenance of cell polarityGO:0007163290.014
negative regulation of cell communicationGO:0010648960.014
positive regulation of inflammatory responseGO:005072910.014
regulation of reproductive processGO:200024140.014
neuromuscular synaptic transmissionGO:000727420.014
negative regulation of cellular response to growth factor stimulusGO:009028890.014
programmed cell deathGO:00125011190.014
response to endogenous stimulusGO:0009719830.014
dna templated transcription elongationGO:000635430.014
peptidyl lysine acetylationGO:001839420.014
action potentialGO:0001508190.014
positive regulation of epithelial cell migrationGO:001063420.014

gsk3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.032
cardiovascular system diseaseDOID:128700.020
musculoskeletal system diseaseDOID:1700.016
connective tissue diseaseDOID:6500.016
bone diseaseDOID:008000100.016
nervous system diseaseDOID:86300.016