Danio rerio

2 known processes

shmt1

serine hydroxymethyltransferase 1 (soluble)

(Aliases: zgc:66171,MGC66171,zgc:77524)

shmt1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.151
embryonic organ developmentGO:00485683810.131
response to nutrientGO:000758430.118
embryonic organ morphogenesisGO:00485622740.112
heart developmentGO:00075073130.110
nucleobase containing compound biosynthetic processGO:00346542050.100
central nervous system developmentGO:00074173870.093
head developmentGO:00603223030.081
embryo development ending in birth or egg hatchingGO:00097922710.077
vasculature developmentGO:00019442780.075
agingGO:000756820.074
regulation of multicellular organismal processGO:00512392770.069
regulation of mrna processingGO:005068430.068
digestive tract developmentGO:00485652650.067
lipid storageGO:001991510.063
digestive system developmentGO:00551232890.062
eye developmentGO:00016542770.062
chordate embryonic developmentGO:00430092710.062
maintenance of locationGO:005123540.059
regulation of nucleobase containing compound metabolic processGO:00192192500.058
regulation of neural precursor cell proliferationGO:200017730.058
aromatic compound biosynthetic processGO:00194382170.056
Human
brain developmentGO:00074202930.056
small molecule metabolic processGO:0044281770.056
Human
guanosine containing compound catabolic processGO:190106920.055
regulation of protein localization to nucleusGO:190018020.054
biosynthetic processGO:00090582940.052
Human
muscle cell differentiationGO:00426921390.052
cell motilityGO:00488702440.052
cellular aromatic compound metabolic processGO:00067252950.051
Human
sensory organ developmentGO:00074233930.051
hematopoietic or lymphoid organ developmentGO:00485341910.050
positive regulation of catabolic processGO:000989640.050
muscle structure developmentGO:00610611960.050
tube morphogenesisGO:00352393490.046
amine metabolic processGO:000930820.045
anterior posterior pattern specificationGO:00099521520.045
response to drugGO:004249330.045
cell part morphogenesisGO:00329902460.045
regulation of developmental processGO:00507932470.044
response to vitaminGO:003327330.044
blood vessel morphogenesisGO:00485142160.044
generation of neuronsGO:00486993850.044
single organism metabolic processGO:00447102170.044
Human
cellular nitrogen compound metabolic processGO:00346412900.043
Human
heterocycle metabolic processGO:00464832900.043
Human
ear developmentGO:00435831270.042
establishment of protein localization to organelleGO:007259440.042
morphogenesis of an epitheliumGO:00020093330.042
regulation of gene expressionGO:00104682650.042
cellular biosynthetic processGO:00442492860.041
Human
organic cyclic compound metabolic processGO:19013603010.041
Human
immune system processGO:00023762410.041
nitrogen compound metabolic processGO:00068073190.041
Human
cell proliferationGO:0008283800.040
nucleobase containing compound metabolic processGO:00061392740.040
Human
response to external stimulusGO:00096052640.040
organic substance biosynthetic processGO:19015762890.039
Human
blood vessel developmentGO:00015682460.039
cellular response to external stimulusGO:007149620.039
protein importGO:001703830.039
response to chemicalGO:00422213200.039
striated muscle tissue developmentGO:00147061100.039
determination of left right symmetryGO:00073681790.039
apoptotic processGO:00069151160.038
heterocycle biosynthetic processGO:00181302150.038
Human
cellular nitrogen compound biosynthetic processGO:00442712180.038
Human
rna biosynthetic processGO:00327741810.037
alpha amino acid metabolic processGO:190160530.037
Human
regulation of cell activationGO:005086510.037
multicellular organism growthGO:003526440.036
organic cyclic compound biosynthetic processGO:19013622230.036
Human
xenobiotic metabolic processGO:000680540.036
determination of heart left right asymmetryGO:00613711170.036
regulation of protein targetingGO:190353320.036
positive regulation of cellular catabolic processGO:003133130.035
positive regulation of transportGO:005105020.035
guanosine containing compound metabolic processGO:190106840.035
positive regulation of purine nucleotide catabolic processGO:003312310.035
mitochondrion organizationGO:000700540.035
organonitrogen compound metabolic processGO:1901564740.035
Human
cell migrationGO:00164772370.035
negative regulation of biological processGO:00485193040.034
hemopoiesisGO:00300971830.034
tissue remodelingGO:004877140.034
signal transductionGO:00071654550.034
protein localization to nucleusGO:003450430.034
organelle organizationGO:00069962270.033
stem cell proliferationGO:007208940.033
regulation of multicellular organism growthGO:004001440.033
response to stressGO:00069502630.033
positive regulation of metabolic processGO:00098931080.033
regulation of cell developmentGO:00602841000.033
negative regulation of macromolecule metabolic processGO:0010605760.033
nucleocytoplasmic transportGO:000691340.032
lipid catabolic processGO:001604240.032
determination of bilateral symmetryGO:00098552040.032
deathGO:00162651210.032
cellular component movementGO:00069283350.031
regionalizationGO:00030022740.031
cellular response to chemical stimulusGO:00708871570.031
cellular macromolecule biosynthetic processGO:00346452240.031
muscle tissue developmentGO:00605371100.030
protein import into nucleusGO:000660630.030
regulation of metal ion transportGO:001095940.030
rna metabolic processGO:00160702190.030
protein targeting to nucleusGO:004474430.030
oxoacid metabolic processGO:0043436310.030
Human
regulation of protein import into nucleusGO:004230620.029
single organism transportGO:00447652060.029
single organism nuclear importGO:190259330.029
regulation of protein transportGO:005122330.029
leukocyte proliferationGO:007066110.029
response to carbohydrateGO:000974330.029
meiotic nuclear divisionGO:000712640.029
specification of symmetryGO:00097992040.029
regulation of nucleic acid templated transcriptionGO:19035062130.029
liver developmentGO:0001889960.028
regulation of establishment of protein localizationGO:007020140.028
cellular amine metabolic processGO:004410620.028
immune system developmentGO:00025201910.028
cell projection morphogenesisGO:00488582440.028
positive regulation of cell activationGO:005086710.028
adult behaviorGO:003053420.028
regulation of biological qualityGO:00650082630.028
nuclear transportGO:005116940.027
cellular response to extracellular stimulusGO:003166820.027
regulation of stem cell proliferationGO:007209120.027
regulation of purine nucleotide catabolic processGO:003312120.027
cognitionGO:005089010.027
regulation of cell differentiationGO:00455951420.026
locomotionGO:00400113130.026
angiogenesisGO:00015251580.026
regulation of macromolecule metabolic processGO:00602553170.026
muscle cell developmentGO:00550011150.026
regulation of nitrogen compound metabolic processGO:00511712510.026
regulation of meiotic cell cycleGO:005144510.026
regulation of reproductive processGO:200024140.026
regulation of apoptotic processGO:0042981980.026
regulation of nucleoside metabolic processGO:000911820.025
cell projection organizationGO:00300302840.025
regulation of protein modification by small protein conjugation or removalGO:190332030.025
negative regulation of cytokine productionGO:000181810.025
negative regulation of cellular processGO:00485232830.025
regulation of cytoplasmic transportGO:190364940.025
b cell activationGO:004211320.025
regulation of anatomical structure morphogenesisGO:00226031300.025
regulation of cellular amine metabolic processGO:003323800.025
mononuclear cell proliferationGO:003294310.025
cellular component biogenesisGO:00440851780.025
Human
cellular response to nutrient levelsGO:003166920.025
positive regulation of cell cycleGO:004578730.025
somite developmentGO:0061053960.025
regulation of cytokine productionGO:000181730.024
skeletal muscle organ developmentGO:0060538780.024
cellular component assemblyGO:00226071700.024
Human
purine containing compound metabolic processGO:0072521290.024
Human
nuclear importGO:005117030.024
neuroblast proliferationGO:000740520.024
regulation of metabolic processGO:00192223590.024
regulation of intracellular protein transportGO:003315730.024
cellular amino acid metabolic processGO:000652070.024
Human
regulation of cellular biosynthetic processGO:00313262450.023
neuron developmentGO:00486662620.023
regulation of wound healingGO:006104120.023
regulation of macromolecule biosynthetic processGO:00105562250.023
protein complex localizationGO:003150310.023
nucleic acid templated transcriptionGO:00976591810.023
regulation of cellular macromolecule biosynthetic processGO:20001122220.023
extrinsic apoptotic signaling pathwayGO:009719130.023
regulation of cellular amino acid metabolic processGO:000652100.023
response to biotic stimulusGO:0009607970.023
regulation of response to stimulusGO:00485832690.023
myotube cell developmentGO:0014904350.023
inositol lipid mediated signalingGO:004801720.023
lymphocyte proliferationGO:004665110.023
cellular component morphogenesisGO:00329893360.022
regulation of transcription dna templatedGO:00063552130.022
regulation of signalingGO:00230512350.022
phagocytosisGO:000690930.022
cellular macromolecule metabolic processGO:00442603910.022
wound healingGO:0042060900.022
skeletal muscle fiber developmentGO:0048741350.022
regulation of rna metabolic processGO:00512522240.022
growthGO:00400071740.022
transmembrane transportGO:00550851200.022
muscle fiber developmentGO:0048747520.022
gtp metabolic processGO:004603940.022
organic acid metabolic processGO:0006082310.022
Human
neuron differentiationGO:00301823530.022
cell fate commitmentGO:0045165990.022
striated muscle cell developmentGO:00550021080.021
gene expressionGO:00104672520.021
positive regulation of biological processGO:00485182530.021
cell cycle g1 s phase transitionGO:004484310.020
positive regulation of nucleotide catabolic processGO:003081310.020
muscle organ developmentGO:00075171010.020
negative regulation of gene expressionGO:0010629650.020
regulation of gtp catabolic processGO:003312420.020
stem cell maintenanceGO:001982740.020
regulation of cellular metabolic processGO:00313233200.020
transcription from rna polymerase ii promoterGO:0006366800.019
gland developmentGO:00487321430.019
cell deathGO:00082191210.019
response to glucoseGO:000974930.019
regulation of transcription from rna polymerase ii promoterGO:00063571140.019
developmental growthGO:00485891660.019
skeletal system developmentGO:00015011810.019
programmed cell deathGO:00125011190.019
estrogen metabolic processGO:000821020.019
regulation of autophagyGO:001050630.019
cellular response to decreased oxygen levelsGO:003629410.019
regulation of rna biosynthetic processGO:20011412130.019
response to external biotic stimulusGO:0043207970.019
adherens junction organizationGO:003433240.019
meiotic cell cycle processGO:190304630.018
macromolecule biosynthetic processGO:00090592270.018
negative regulation of kinase activityGO:003367340.018
positive regulation of nucleoside metabolic processGO:004597910.018
cell substrate adhesionGO:003158940.018
epithelial tube morphogenesisGO:00605621480.018
cell morphogenesis involved in differentiationGO:00009041950.018
protein stabilizationGO:005082120.018
nucleobase containing small molecule metabolic processGO:0055086320.018
Human
regulation of tube sizeGO:003515020.018
regulation of cellular ketone metabolic processGO:001056570.018
regulation of bindingGO:005109830.018
regulation of inflammatory responseGO:005072720.018
cellular response to organic substanceGO:00713101050.018
response to monosaccharideGO:003428430.018
regulation of skeletal muscle fiber developmentGO:004874220.017
gtp catabolic processGO:000618420.017
positive regulation of gtp catabolic processGO:003312610.017
response to woundingGO:00096111160.017
transcription dna templatedGO:00063511810.017
carboxylic acid metabolic processGO:0019752220.017
Human
camera type eye developmentGO:00430102220.017
negative regulation of defense responseGO:003134820.017
regulation of nucleocytoplasmic transportGO:004682220.017
cellular response to starvationGO:000926710.017
rna localizationGO:000640340.017
response to xenobiotic stimulusGO:0009410450.017
nucleic acid metabolic processGO:00903042440.016
cellular ketone metabolic processGO:0042180110.016
regulation of mrna splicing via spliceosomeGO:004802430.016
cellular response to hypoxiaGO:007145610.016
digestive tract morphogenesisGO:00485462310.016
meiosis iGO:000712710.016
synaptic growth at neuromuscular junctionGO:005112420.016
mesenchyme developmentGO:00604851270.016
negative regulation of protein phosphorylationGO:000193340.016
nucleoside monophosphate catabolic processGO:000912540.016
transportGO:00068102200.016
somitogenesisGO:0001756870.015
cell morphogenesis involved in neuron differentiationGO:00486671630.015
regulation of transmembrane transporter activityGO:002289820.015
ameboidal type cell migrationGO:00016671430.015
positive regulation of cytokine productionGO:000181920.015
organic acid catabolic processGO:001605430.015
Human
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.015
multi organism processGO:00517041340.015
regulation of nucleotide catabolic processGO:003081120.015
heart loopingGO:0001947940.015
compound eye developmentGO:004874920.015
cellular modified amino acid metabolic processGO:000657530.015
Human
regulation of i kappab kinase nf kappab signalingGO:004312240.015
regulation of cell deathGO:00109411030.015
catabolic processGO:0009056320.015
Human
negative regulation of protein kinase activityGO:000646940.015
positive regulation of cellular amine metabolic processGO:003324000.015
cellular response to xenobiotic stimulusGO:0071466350.015
regulation of skeletal muscle tissue developmentGO:004864140.015
cell cycleGO:0007049930.015
cell morphogenesisGO:00009022890.015
positive regulation of gtpase activityGO:004354710.015
oxidation reduction processGO:0055114410.015
negative regulation of rna metabolic processGO:0051253480.014
i kappab kinase nf kappab signalingGO:000724940.014
establishment of localizationGO:00512342440.014
regulation of gtpase activityGO:004308720.014
appendage developmentGO:0048736800.014
response to hexoseGO:000974630.014
regulation of myotube differentiationGO:001083020.014
regulation of cell communicationGO:00106462320.014
mrna metabolic processGO:0016071200.014
regulation of programmed cell deathGO:00430671010.014
localization of cellGO:00516742440.014
positive regulation of wound healingGO:009030310.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.014
phagocytosis engulfmentGO:000691110.014
purine ribonucleoside biosynthetic processGO:004612920.014
striated muscle cell differentiationGO:00511461290.014
production of molecular mediator of immune responseGO:000244020.014
cellular response to oxygen levelsGO:007145310.013
sleepGO:003043110.013
inner ear developmentGO:00488391260.013
purine nucleoside monophosphate catabolic processGO:000912840.013
proteolysis involved in cellular protein catabolic processGO:005160330.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
single organism localizationGO:19025782250.013
organonitrogen compound biosynthetic processGO:1901566470.013
Human
regulation of response to biotic stimulusGO:000283120.013
negative regulation of dna metabolic processGO:005105340.013
homeostasis of number of cellsGO:0048872620.013
purine ribonucleoside monophosphate catabolic processGO:000916940.013
response to organic substanceGO:00100331530.013
hepaticobiliary system developmentGO:0061008980.013
b cell mediated immunityGO:001972430.013
embryonic hemopoiesisGO:0035162530.013
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.013
regulation of oocyte developmentGO:006028130.013
proteasomal protein catabolic processGO:001049820.013
lipid oxidationGO:003444010.013
mitotic dna integrity checkpointGO:004477440.013
connective tissue developmentGO:0061448990.013
negative regulation of apoptotic processGO:0043066550.013
modification dependent macromolecule catabolic processGO:004363230.013
regulation of multicellular organismal developmentGO:20000262230.012
multicellular organismal metabolic processGO:004423620.012
protein homooligomerizationGO:005126030.012
gastrulationGO:00073692080.012
response to endogenous stimulusGO:0009719830.012
small molecule catabolic processGO:004428230.012
Human
regulation of microtubule cytoskeleton organizationGO:007050730.012
embryonic heart tube developmentGO:00350501330.012
regulation of primary metabolic processGO:00800903110.012
neurotransmitter secretionGO:000726920.012
sulfur compound biosynthetic processGO:004427290.012
immunoglobulin mediated immune responseGO:001606430.012
regulation of extrinsic apoptotic signaling pathwayGO:200123630.012
negative regulation of catabolic processGO:000989530.012
negative regulation of multicellular organismal processGO:0051241690.012
response to lipidGO:0033993600.012
tissue regenerationGO:0042246740.012
g1 s transition of mitotic cell cycleGO:000008210.012
negative regulation of metabolic processGO:0009892860.012
regulation of biosynthetic processGO:00098892500.012
cell surface receptor signaling pathwayGO:00071663250.012
regulation of organ growthGO:004662030.012
organophosphate metabolic processGO:0019637370.012
positive regulation of developmental processGO:0051094500.012
cellular lipid catabolic processGO:004424230.012
mitochondrial transportGO:000683920.012
single organism organelle organizationGO:19025891990.012
cellular protein catabolic processGO:004425740.012
negative regulation of protein transportGO:005122430.012
autophagyGO:000691440.012
zymogen activationGO:003163830.012
positive regulation of cellular metabolic processGO:0031325940.012
lipid metabolic processGO:0006629520.012
regulation of blood vessel sizeGO:005088020.012
blood circulationGO:0008015870.012
positive regulation of cellular component biogenesisGO:004408930.012
positive regulation of nitrogen compound metabolic processGO:0051173690.011
positive regulation of i kappab kinase nf kappab signalingGO:004312330.011
regulation of dna replicationGO:000627530.011
chemotaxisGO:00069351040.011
response to alkaloidGO:004327920.011
pigmentationGO:0043473850.011
regulation of protein bindingGO:004339330.011
intracellular signal transductionGO:0035556850.011
protein polymerizationGO:005125840.011
axonogenesisGO:00074091520.011
response to other organismGO:0051707970.011
retina morphogenesis in camera type eyeGO:0060042790.011
ubiquitin dependent protein catabolic processGO:000651130.011
myotube differentiationGO:0014902450.011
mesoderm developmentGO:0007498880.011
nuclear migrationGO:000709730.011
water homeostasisGO:003010440.011
regulation of circadian rhythmGO:004275240.011
cellular monovalent inorganic cation homeostasisGO:003000420.011
negative regulation of cellular metabolic processGO:0031324770.011
peptide transportGO:001583310.011
nucleoside biosynthetic processGO:000916320.011
nuclear exportGO:005116810.011
positive regulation of chromatin modificationGO:190331010.011
positive regulation of chromosome organizationGO:200125210.011
protein metabolic processGO:00195381830.011
positive regulation of neural precursor cell proliferationGO:200017910.011
ribonucleoside biosynthetic processGO:004245520.011
neuron projection morphogenesisGO:00488121610.011
intracellular mrna localizationGO:000829810.011
homeostatic processGO:00425921420.011
multi organism cellular processGO:004476420.011
sulfur compound metabolic processGO:0006790130.011
peptidyl serine modificationGO:001820920.010
negative regulation of multi organism processGO:004390130.010
stem cell fate commitmentGO:004886510.010
cellular protein metabolic processGO:00442671290.010
negative regulation of transcription dna templatedGO:0045892450.010
fatty acid oxidationGO:001939510.010
embryonic heart tube morphogenesisGO:00031431080.010
regulation of signal transductionGO:00099662250.010
carboxylic acid catabolic processGO:004639530.010
Human
positive regulation of small gtpase mediated signal transductionGO:005105710.010
response to abiotic stimulusGO:00096281220.010
response to transition metal nanoparticleGO:1990267280.010
neuroblast fate commitmentGO:001401710.010
regulation of calcium ion transportGO:005192420.010
axis specificationGO:0009798430.010
positive regulation of cytoskeleton organizationGO:005149530.010
embryonic skeletal system morphogenesisGO:0048704930.010
response to uvGO:000941130.010
neurotransmitter transportGO:000683620.010
regulation of neurotransmitter transportGO:005158810.010

shmt1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.049
inherited metabolic disorderDOID:65500.029
disease of metabolismDOID:001466700.029
nervous system diseaseDOID:86300.017
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.013
organ system cancerDOID:005068600.013
cardiovascular system diseaseDOID:128700.013