Danio rerio

17 known processes

mlphb

melanophilin b

(Aliases: MGC154096,zgc:154096,si:ch211-186m12.3)

mlphb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular pigmentationGO:0033059300.763
pigmentationGO:0043473850.424
epithelial cell differentiationGO:00308551160.234
Mouse
tissue remodelingGO:004877140.193
developmental pigmentationGO:0048066480.192
Mouse
regulation of primary metabolic processGO:00800903110.180
hemopoiesisGO:00300971830.175
establishment of pigment granule localizationGO:0051905220.172
regulation of gene expressionGO:00104682650.169
cellular aromatic compound metabolic processGO:00067252950.152
nitrogen compound metabolic processGO:00068073190.114
cellular component assemblyGO:00226071700.113
cellular nitrogen compound metabolic processGO:00346412900.110
organic substance biosynthetic processGO:19015762890.110
melanocyte differentiationGO:0030318260.108
Mouse
negative regulation of cellular processGO:00485232830.108
transcription dna templatedGO:00063511810.107
cellular macromolecule metabolic processGO:00442603910.106
macromolecule biosynthetic processGO:00090592270.106
organic cyclic compound metabolic processGO:19013603010.100
biosynthetic processGO:00090582940.099
neuroepithelial cell differentiationGO:0060563260.093
Mouse
regulation of transcription dna templatedGO:00063552130.092
nucleobase containing compound biosynthetic processGO:00346542050.092
cellular macromolecule biosynthetic processGO:00346452240.091
heterocycle metabolic processGO:00464832900.091
organic cyclic compound biosynthetic processGO:19013622230.089
nucleobase containing compound metabolic processGO:00061392740.088
larval developmentGO:000216420.088
actin filament based movementGO:003004810.088
regulation of macromolecule biosynthetic processGO:00105562250.085
establishment of organelle localizationGO:0051656450.083
rna biosynthetic processGO:00327741810.083
canonical wnt signaling pathwayGO:0060070480.082
positive regulation of nitrogen compound metabolic processGO:0051173690.082
regulation of biosynthetic processGO:00098892500.082
sensory organ developmentGO:00074233930.082
regulation of cellular macromolecule biosynthetic processGO:20001122220.079
regulation of endocrine processGO:004406020.077
ion transmembrane transportGO:0034220910.077
gene expressionGO:00104672520.074
chordate embryonic developmentGO:00430092710.072
columnar cuboidal epithelial cell differentiationGO:0002065380.072
Mouse
regulation of nucleobase containing compound metabolic processGO:00192192500.071
immune system developmentGO:00025201910.069
skeletal system developmentGO:00015011810.068
regulation of cellular biosynthetic processGO:00313262450.068
cell surface receptor signaling pathwayGO:00071663250.068
heterocycle biosynthetic processGO:00181302150.067
transmembrane transportGO:00550851200.066
nucleic acid templated transcriptionGO:00976591810.065
rna metabolic processGO:00160702190.063
regulation of nucleic acid templated transcriptionGO:19035062130.062
regulation of nitrogen compound metabolic processGO:00511712510.061
aromatic compound biosynthetic processGO:00194382170.061
regulation of macromolecule metabolic processGO:00602553170.060
apoptotic processGO:00069151160.059
camera type eye developmentGO:00430102220.059
positive regulation of biological processGO:00485182530.058
protein secretionGO:000930610.055
regulation of metabolic processGO:00192223590.054
pigment granule localizationGO:0051875250.054
regulation of rna metabolic processGO:00512522240.054
ear developmentGO:00435831270.053
embryonic organ developmentGO:00485683810.053
agingGO:000756820.053
establishment of vesicle localizationGO:0051650240.052
inner ear developmentGO:00488391260.050
wnt signaling pathwayGO:0016055800.050
positive regulation of cellular biosynthetic processGO:0031328680.048
nucleic acid metabolic processGO:00903042440.047
maintenance of locationGO:005123540.046
regulation of cell shapeGO:000836010.046
adult behaviorGO:003053420.046
cellular biosynthetic processGO:00442492860.045
positive regulation of catabolic processGO:000989640.044
gtp metabolic processGO:004603940.044
leukocyte differentiationGO:0002521250.041
regulation of rna biosynthetic processGO:20011412130.041
organonitrogen compound metabolic processGO:1901564740.040
vesicle localizationGO:0051648270.039
regulation of protein transportGO:005122330.039
secondary metabolic processGO:001974830.039
embryonic organ morphogenesisGO:00485622740.039
guanosine containing compound catabolic processGO:190106920.039
positive regulation of cellular catabolic processGO:003133130.039
regulation of cellular metabolic processGO:00313233200.039
organelle organizationGO:00069962270.038
myeloid cell differentiationGO:0030099860.038
fin developmentGO:0033333770.038
guanosine containing compound metabolic processGO:190106840.037
regulation of tube sizeGO:003515020.037
deathGO:00162651210.037
generation of neuronsGO:00486993850.036
positive regulation of macromolecule biosynthetic processGO:0010557590.035
catechol containing compound metabolic processGO:000971220.035
cell fate commitmentGO:0045165990.035
transcription from rna polymerase ii promoterGO:0006366800.035
single organism transportGO:00447652060.035
Mouse
regulation of synaptic plasticityGO:004816710.035
eye developmentGO:00016542770.034
positive regulation of biosynthetic processGO:0009891680.034
regulation of multicellular organismal developmentGO:20000262230.034
positive regulation of rna metabolic processGO:0051254590.034
single organism organelle organizationGO:19025891990.033
lamellipodium assemblyGO:003003210.032
cell deathGO:00082191210.032
cellular localizationGO:0051641970.032
positive regulation of rna biosynthetic processGO:1902680570.032
melanin metabolic processGO:000658220.032
system processGO:00030081850.032
cell morphogenesisGO:00009022890.032
negative regulation of biological processGO:00485193040.032
positive regulation of nucleobase containing compound metabolic processGO:0045935690.032
hematopoietic or lymphoid organ developmentGO:00485341910.031
positive regulation of nucleic acid templated transcriptionGO:1903508570.031
connective tissue developmentGO:0061448990.031
establishment of localization in cellGO:0051649770.030
regulation of purine nucleotide catabolic processGO:003312120.030
appendage developmentGO:0048736800.030
positive regulation of cellular processGO:00485222010.030
regulation of nucleotide catabolic processGO:003081120.030
negative regulation of transcription dna templatedGO:0045892450.030
positive regulation of transcription dna templatedGO:0045893570.030
positive regulation of translationGO:004572710.030
embryo development ending in birth or egg hatchingGO:00097922710.029
stem cell maintenanceGO:001982740.029
lamellipodium organizationGO:009758110.029
establishment of localizationGO:00512342440.028
regulation of multicellular organism growthGO:004001440.028
digestive system developmentGO:00551232890.028
hindbrain developmentGO:0030902910.028
cellular component movementGO:00069283350.028
brain developmentGO:00074202930.027
myeloid leukocyte differentiationGO:0002573150.027
negative regulation of programmed cell deathGO:0043069580.027
positive regulation of gene expressionGO:0010628710.027
cellular component biogenesisGO:00440851780.026
regulation of cellular amine metabolic processGO:003323800.026
phagocytosisGO:000690930.026
cellular amine metabolic processGO:004410620.026
ribonucleoside monophosphate catabolic processGO:000915840.026
heart developmentGO:00075073130.025
small molecule metabolic processGO:0044281770.025
positive regulation of nucleoside metabolic processGO:004597910.025
gtp catabolic processGO:000618420.025
regulation of nucleoside metabolic processGO:000911820.025
regulation of apoptotic processGO:0042981980.025
action potentialGO:0001508190.025
retina development in camera type eyeGO:00600411460.025
regulation of transmembrane transportGO:0034762180.024
urogenital system developmentGO:0001655970.024
multicellular organism growthGO:003526440.024
lipid storageGO:001991510.024
morphogenesis of an epitheliumGO:00020093330.024
embryonic skeletal joint developmentGO:007249830.023
embryonic limb morphogenesisGO:003032620.023
regulation of membrane potentialGO:0042391230.023
purine nucleoside monophosphate catabolic processGO:000912840.023
regulation of transcription from rna polymerase ii promoterGO:00063571140.023
positive regulation of transportGO:005105020.023
nucleoside monophosphate catabolic processGO:000912540.023
digestive tract developmentGO:00485652650.023
bone remodelingGO:004684920.023
regulation of multicellular organismal processGO:00512392770.023
head developmentGO:00603223030.022
regulation of cell differentiationGO:00455951420.022
meiotic nuclear divisionGO:000712640.022
ubiquitin dependent protein catabolic processGO:000651130.022
stem cell proliferationGO:007208940.022
cation transmembrane transportGO:0098655650.022
cognitionGO:005089010.021
response to chemicalGO:00422213200.021
amine metabolic processGO:000930820.021
activation of mapk activityGO:000018730.021
response to topologically incorrect proteinGO:003596620.021
inorganic ion transmembrane transportGO:0098660570.021
organelle localizationGO:0051640490.021
proteasomal protein catabolic processGO:001049820.021
mesenchyme developmentGO:00604851270.021
cellular amide metabolic processGO:004360340.020
positive regulation of purine nucleotide catabolic processGO:003312310.020
tube morphogenesisGO:00352393490.020
cellular component assembly involved in morphogenesisGO:00109271070.020
wound healingGO:0042060900.020
ion transportGO:00068111140.020
cell morphogenesis involved in differentiationGO:00009041950.020
regulation of signal transductionGO:00099662250.020
sensory perception of chemical stimulusGO:000760630.020
neural crest cell differentiationGO:0014033720.020
circulatory system processGO:0003013870.020
positive regulation of cellular metabolic processGO:0031325940.020
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.020
regulation of cell activationGO:005086510.020
regulation of circadian rhythmGO:004275240.020
regulation of establishment of protein localizationGO:007020140.020
cellular component morphogenesisGO:00329893360.020
localization of cellGO:00516742440.019
chemosensory behaviorGO:000763510.019
positive regulation of nucleotide catabolic processGO:003081310.019
regulation of gtp catabolic processGO:003312420.019
compound eye developmentGO:004874920.019
neuron differentiationGO:00301823530.019
digestive tract morphogenesisGO:00485462310.019
pigment granule transportGO:0051904190.019
regulation of blood pressureGO:000821710.019
positive regulation of apoptotic signaling pathwayGO:200123510.019
single organism localizationGO:19025782250.019
Mouse
positive regulation of gtpase activityGO:004354710.019
growthGO:00400071740.019
modification dependent macromolecule catabolic processGO:004363230.019
pigment granule aggregation in cell centerGO:005187780.019
regulation of muscle contractionGO:000693730.019
response to drugGO:004249330.019
post golgi vesicle mediated transportGO:000689210.018
cilium morphogenesisGO:0060271850.018
organelle assemblyGO:00709251100.018
developmental programmed cell deathGO:001062340.018
vasculature developmentGO:00019442780.018
regulation of cellular amino acid metabolic processGO:000652100.018
membrane invaginationGO:001032410.018
oxoacid metabolic processGO:0043436310.018
cellular amino acid metabolic processGO:000652070.018
regulation of gtpase activityGO:004308720.018
regulation of myeloid leukocyte differentiationGO:000276150.018
organelle fusionGO:004828430.018
cardiac muscle cell contractionGO:008600310.018
gastrulationGO:00073692080.018
regulation of systemic arterial blood pressureGO:000307310.018
inner ear morphogenesisGO:0042472630.018
central nervous system developmentGO:00074173870.018
sensory organ morphogenesisGO:00905962000.018
immune system processGO:00023762410.017
cilium assemblyGO:0042384580.017
neural crest cell developmentGO:0014032620.017
skeletal system morphogenesisGO:00487051020.017
cartilage developmentGO:0051216960.017
response to monosaccharideGO:003428430.017
ear morphogenesisGO:0042471640.017
cell projection organizationGO:00300302840.017
carboxylic acid metabolic processGO:0019752220.017
cell projection morphogenesisGO:00488582440.017
neuron neuron synaptic transmissionGO:000727010.017
regulation of cytokine productionGO:000181730.017
single organism metabolic processGO:00447102170.017
melanosome transportGO:0032402190.017
response to external stimulusGO:00096052640.017
microtubule based movementGO:0007018330.017
striated muscle cell differentiationGO:00511461290.017
muscle cell differentiationGO:00426921390.017
cellular response to topologically incorrect proteinGO:003596720.017
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.017
regulation of protein catabolic processGO:004217610.017
monovalent inorganic cation transportGO:0015672420.016
positive regulation of cell cycleGO:004578730.016
heart contractionGO:0060047710.016
developmental growthGO:00485891660.016
response to organic substanceGO:00100331530.016
startle responseGO:000196440.016
cell migrationGO:00164772370.016
striated muscle cell developmentGO:00550021080.016
periodic partitioningGO:000736510.016
protein polymerizationGO:005125840.016
cellular potassium ion transportGO:0071804100.016
protein stabilizationGO:005082120.016
nucleocytoplasmic transportGO:000691340.016
regulation of neural precursor cell proliferationGO:200017730.016
signal transductionGO:00071654550.015
macromolecular complex assemblyGO:0065003350.015
muscle structure developmentGO:00610611960.015
negative regulation of gene expressionGO:0010629650.015
gland developmentGO:00487321430.015
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.015
specification of symmetryGO:00097992040.015
membrane fusionGO:006102520.015
mesenchymal cell developmentGO:0014031780.015
centrosome organizationGO:005129710.015
proteolysis involved in cellular protein catabolic processGO:005160330.015
cellular nitrogen compound biosynthetic processGO:00442712180.015
regulation of signalingGO:00230512350.015
single organism membrane fusionGO:004480120.015
positive regulation of cellular component biogenesisGO:004408930.015
negative regulation of macromolecule biosynthetic processGO:0010558480.015
cellular response to external stimulusGO:007149620.015
regulation of response to stimulusGO:00485832690.015
cellular protein metabolic processGO:00442671290.014
regulation of rho protein signal transductionGO:003502320.014
locomotor rhythmGO:004547530.014
endoplasmic reticulum unfolded protein responseGO:003096820.014
regulation of protein complex assemblyGO:004325430.014
inorganic cation transmembrane transportGO:0098662500.014
cellular component disassemblyGO:002241110.014
positive regulation of epithelial cell proliferationGO:005067910.014
synaptic vesicle recyclingGO:003646510.014
modification dependent protein catabolic processGO:001994130.014
regulation of localizationGO:00328791040.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
hormone secretionGO:004687920.014
nuclear importGO:005117030.014
production of molecular mediator of immune responseGO:000244020.014
regulation of bindingGO:005109830.014
regenerationGO:0031099910.014
organism emergence from protective structureGO:007168440.014
intracellular signal transductionGO:0035556850.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.014
atp catabolic processGO:000620040.014
positive regulation of secretionGO:005104710.014
neural crest formationGO:0014029140.014
hormone transportGO:000991420.014
sequestering of metal ionGO:005123830.014
meiotic cell cycle processGO:190304630.014
ectodermal placode developmentGO:0071696370.013
negative regulation of biosynthetic processGO:0009890550.013
regulation of meiotic cell cycleGO:005144510.013
neuromuscular process controlling balanceGO:005088530.013
glial cell migrationGO:000834730.013
cell motilityGO:00488702440.013
protein metabolic processGO:00195381830.013
positive regulation of gtp catabolic processGO:003312610.013
negative regulation of cytokine productionGO:000181810.013
negative regulation of cell deathGO:0060548600.013
alpha amino acid metabolic processGO:190160530.013
mesenchymal cell differentiationGO:0048762870.013
neuroblast proliferationGO:000740520.013
purine ribonucleoside monophosphate catabolic processGO:000916940.013
positive regulation of stress activated mapk cascadeGO:003287430.013
embryonic cranial skeleton morphogenesisGO:0048701900.013
regulation of jak stat cascadeGO:004642530.013
regulation of cellular ketone metabolic processGO:001056570.013
fin morphogenesisGO:0033334530.013
positive regulation of metabolic processGO:00098931080.013
golgi vesicle transportGO:004819330.013
neurological system processGO:0050877620.013
determination of bilateral symmetryGO:00098552040.013
regulation of cell deathGO:00109411030.013
peptidyl serine phosphorylationGO:001810510.013
phenol containing compound biosynthetic processGO:004618940.013
response to alkaloidGO:004327920.013
enzyme linked receptor protein signaling pathwayGO:00071671060.013
cell proliferationGO:0008283800.013
peptide transportGO:001583310.013
protein complex biogenesisGO:0070271300.013
i kappab kinase nf kappab signalingGO:000724940.013
response to woundingGO:00096111160.013
negative regulation of nucleobase containing compound metabolic processGO:0045934590.013
negative regulation of rna metabolic processGO:0051253480.012
embryonic skeletal system developmentGO:0048706970.012
regulation of sequestering of calcium ionGO:005128240.012
striated muscle tissue developmentGO:00147061100.012
positive regulation of notch signaling pathwayGO:004574730.012
phagocytosis engulfmentGO:000691110.012
cellular protein catabolic processGO:004425740.012
establishment of synaptic vesicle localizationGO:009748010.012
mechanosensory behaviorGO:000763820.012
establishment of melanosome localizationGO:0032401190.012
regulation of heart rateGO:000202750.012
mitochondrion organizationGO:000700540.012
cell part morphogenesisGO:00329902460.012
response to carbohydrateGO:000974330.012
regulation of reproductive processGO:200024140.012
cation transportGO:0006812810.012
development of primary female sexual characteristicsGO:004654540.012
synaptic growth at neuromuscular junctionGO:005112420.012
cytoskeleton organizationGO:0007010960.012
melanosome localizationGO:0032400210.012
Mouse
negative regulation of rna biosynthetic processGO:1902679450.012
cell substrate junction assemblyGO:000704420.012
neuronal action potentialGO:0019228180.012
lateral inhibitionGO:004633110.012
regulation of cell communicationGO:00106462320.012
spermatid developmentGO:000728620.012
regulation of anatomical structure morphogenesisGO:00226031300.012
actin filament polymerizationGO:003004120.012
negative regulation of protein kinase activityGO:000646940.012
negative regulation of protein phosphorylationGO:000193340.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
positive regulation of cellular amine metabolic processGO:003324000.012
negative regulation of nitrogen compound metabolic processGO:0051172590.012
determination of left right symmetryGO:00073681790.011
extrinsic apoptotic signaling pathwayGO:009719130.011
centrosome cycleGO:000709810.011
cilium organizationGO:0044782710.011
negative regulation of macromolecule metabolic processGO:0010605760.011
cardiac atrium developmentGO:000323040.011
protein complex assemblyGO:0006461300.011
homeostatic processGO:00425921420.011
cellular response to extracellular stimulusGO:003166820.011
regulation of programmed cell deathGO:00430671010.011
positive regulation of secretion by cellGO:190353210.011
negative regulation of cellular biosynthetic processGO:0031327550.011
programmed cell deathGO:00125011190.011
regulation of stem cell proliferationGO:007209120.011
actomyosin structure organizationGO:0031032530.011
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.011
stem cell developmentGO:0048864820.011
establishment of protein localization to organelleGO:007259440.011
autophagyGO:000691440.011
cell projection assemblyGO:0030031640.011
negative regulation of signal transductionGO:0009968940.011
antimicrobial humoral responseGO:001973020.011
negative regulation of cellular metabolic processGO:0031324770.011
protein localization to nucleusGO:003450430.011
cellular response to xenobiotic stimulusGO:0071466350.011
peripheral nervous system developmentGO:0007422550.011
otic vesicle developmentGO:0071599420.011
spermatid differentiationGO:004851520.011
meiotic chromosome segregationGO:004513230.011
cell cycle g2 m phase transitionGO:004483940.011
muscle cell developmentGO:00550011150.011
apoptotic process involved in developmentGO:190274220.011
response to unfolded proteinGO:000698620.011
heart processGO:0003015710.011
carbohydrate homeostasisGO:003350010.011
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.011
stem cell differentiationGO:00488631170.011
rna localizationGO:000640340.011
regionalizationGO:00030022740.011
rna transportGO:005065820.011
polarized epithelial cell differentiationGO:003085940.011
epithelial tube morphogenesisGO:00605621480.011
negative regulation of defense responseGO:003134820.011
negative regulation of nucleic acid templated transcriptionGO:1903507450.011
protein complex disassemblyGO:004324110.011
organic substance transportGO:0071702580.011
Mouse
positive regulation of exocytosisGO:004592110.011
response to stressGO:00069502630.011
negative regulation of reproductive processGO:200024230.011
cellular response to estradiol stimulusGO:007139210.010
synaptic vesicle transportGO:004848910.010
regulation of protein polymerizationGO:003227120.010
embryonic skeletal joint morphogenesisGO:006027230.010
cellular response to radiationGO:007147840.010
locomotionGO:00400113130.010
macromolecular complex disassemblyGO:003298410.010
regulation of biological qualityGO:00650082630.010
embryonic hemopoiesisGO:0035162530.010
germ line stem cell maintenanceGO:003071820.010
response to hydrogen peroxideGO:004254230.010
regulation of cytoplasmic transportGO:190364940.010
synaptic vesicle localizationGO:009747910.010
cellular protein modification processGO:00064641000.010
actin polymerization or depolymerizationGO:000815420.010
negative regulation of multi organism processGO:004390130.010
transportGO:00068102200.010
Mouse
positive regulation of protein complex assemblyGO:003133420.010
response to uvGO:000941130.010
pigment cell differentiationGO:0050931380.010
Mouse
ameboidal type cell migrationGO:00016671430.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.010

mlphb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.041
disease of cellular proliferationDOID:1456600.016
nervous system diseaseDOID:86300.015
organ system cancerDOID:005068600.014
cancerDOID:16200.014
gastrointestinal system cancerDOID:311900.010